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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for PGR

Z-value: 0.67

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Transcription factors associated with PGR

Gene Symbol Gene ID Gene Info
PGR
ENSG00000082175.10 progesterone receptor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PGRhg19_v2_chr11_-_100999775_100999801-0.236.6e-01Click!

Activity profile of PGR motif

Sorted Z-values of PGR motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_615570 0.60 ENST00000525445.1
ENST00000348655.6
ENST00000397566.1
IRF7
interferon regulatory factor 7
chr1_+_209859510 0.50 ENST00000367028.2
ENST00000261465.1
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr7_-_127672146 0.47 ENST00000476782.1
LRRC4
leucine rich repeat containing 4
chr7_-_5821225 0.42 ENST00000416985.1
RNF216
ring finger protein 216
chr14_+_24641062 0.40 ENST00000311457.3
ENST00000557806.1
ENST00000559919.1
REC8
REC8 meiotic recombination protein
chr6_+_76330355 0.34 ENST00000483859.2
SENP6
SUMO1/sentrin specific peptidase 6
chr2_+_38177575 0.34 ENST00000407257.1
ENST00000417700.2
ENST00000234195.3
ENST00000442857.1
RMDN2
regulator of microtubule dynamics 2
chrX_+_38420623 0.32 ENST00000378482.2
TSPAN7
tetraspanin 7
chr17_+_39846114 0.32 ENST00000586699.1
EIF1
eukaryotic translation initiation factor 1
chr16_-_3350614 0.32 ENST00000268674.2
TIGD7
tigger transposable element derived 7
chr12_+_21654714 0.30 ENST00000542038.1
ENST00000540141.1
ENST00000229314.5
GOLT1B
golgi transport 1B
chr2_+_9778872 0.28 ENST00000478468.1
RP11-521D12.1
RP11-521D12.1
chr6_-_150212029 0.28 ENST00000529948.1
ENST00000357183.4
ENST00000367363.3
RAET1E
retinoic acid early transcript 1E
chr3_-_149051194 0.27 ENST00000470080.1
TM4SF18
transmembrane 4 L six family member 18
chr15_-_29745003 0.27 ENST00000560082.1
FAM189A1
family with sequence similarity 189, member A1
chr3_-_114035026 0.26 ENST00000570269.1
RP11-553L6.5
RP11-553L6.5
chr4_+_108815402 0.25 ENST00000503385.1
SGMS2
sphingomyelin synthase 2
chr3_-_49722523 0.25 ENST00000448220.1
MST1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr2_-_219925189 0.25 ENST00000295731.6
IHH
indian hedgehog
chr14_+_29299437 0.24 ENST00000550827.1
ENST00000548087.1
ENST00000551588.1
ENST00000550122.1
CTD-2384A14.1
CTD-2384A14.1
chr12_+_57849048 0.24 ENST00000266646.2
INHBE
inhibin, beta E
chr12_-_7244469 0.24 ENST00000538050.1
ENST00000536053.2
C1R
complement component 1, r subcomponent
chr10_-_94301107 0.23 ENST00000436178.1
IDE
insulin-degrading enzyme
chr11_+_35222629 0.23 ENST00000526553.1
CD44
CD44 molecule (Indian blood group)
chr5_+_148442844 0.21 ENST00000515519.1
CTC-529P8.1
CTC-529P8.1
chr6_+_27107053 0.21 ENST00000354348.2
HIST1H4I
histone cluster 1, H4i
chr4_-_89442940 0.21 ENST00000527353.1
PIGY
phosphatidylinositol glycan anchor biosynthesis, class Y
chr2_-_74776586 0.21 ENST00000420535.1
LOXL3
lysyl oxidase-like 3
chr9_+_127615733 0.21 ENST00000373574.1
WDR38
WD repeat domain 38
chr4_+_79567362 0.20 ENST00000512322.1
RP11-792D21.2
long intergenic non-protein coding RNA 1094
chr2_-_179315786 0.20 ENST00000457633.1
ENST00000438687.3
ENST00000325748.4
PRKRA
protein kinase, interferon-inducible double stranded RNA dependent activator
chr4_+_86525299 0.19 ENST00000512201.1
ARHGAP24
Rho GTPase activating protein 24
chr6_-_76203454 0.19 ENST00000237172.7
FILIP1
filamin A interacting protein 1
chr4_+_39699664 0.19 ENST00000261427.5
ENST00000510934.1
ENST00000295963.6
UBE2K
ubiquitin-conjugating enzyme E2K
chr7_+_22766766 0.19 ENST00000426291.1
ENST00000401651.1
ENST00000258743.5
ENST00000420258.2
ENST00000407492.1
ENST00000401630.3
ENST00000406575.1
IL6
interleukin 6 (interferon, beta 2)
chr13_-_52026730 0.19 ENST00000420668.2
INTS6
integrator complex subunit 6
chr13_-_52027134 0.18 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
INTS6
integrator complex subunit 6
chr4_-_146019693 0.18 ENST00000514390.1
ANAPC10
anaphase promoting complex subunit 10
chr18_+_61445007 0.18 ENST00000447428.1
ENST00000546027.1
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr12_-_125401885 0.18 ENST00000542416.1
UBC
ubiquitin C
chr3_-_149510553 0.18 ENST00000462519.2
ENST00000446160.1
ENST00000383050.3
ANKUB1
ankyrin repeat and ubiquitin domain containing 1
chr7_-_14026063 0.18 ENST00000443608.1
ENST00000438956.1
ETV1
ets variant 1
chr10_+_73156664 0.17 ENST00000398809.4
ENST00000398842.3
ENST00000461841.3
ENST00000299366.7
CDH23
cadherin-related 23
chr12_+_28410128 0.17 ENST00000381259.1
ENST00000381256.1
CCDC91
coiled-coil domain containing 91
chr2_-_99797390 0.17 ENST00000422537.2
MITD1
MIT, microtubule interacting and transport, domain containing 1
chr8_+_27184320 0.17 ENST00000522517.1
PTK2B
protein tyrosine kinase 2 beta
chr2_+_60983361 0.17 ENST00000238714.3
PAPOLG
poly(A) polymerase gamma
chr8_-_82644562 0.17 ENST00000520604.1
ENST00000521742.1
ENST00000520635.1
ZFAND1
zinc finger, AN1-type domain 1
chr1_+_172422026 0.17 ENST00000367725.4
C1orf105
chromosome 1 open reading frame 105
chr17_-_70053866 0.16 ENST00000540802.1
RP11-84E24.2
RP11-84E24.2
chr2_+_232135245 0.16 ENST00000446447.1
ARMC9
armadillo repeat containing 9
chr2_+_234601512 0.16 ENST00000305139.6
UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6
chr13_+_78315528 0.16 ENST00000496045.1
SLAIN1
SLAIN motif family, member 1
chr5_-_95018660 0.16 ENST00000395899.3
ENST00000274432.8
SPATA9
spermatogenesis associated 9
chr14_-_35182994 0.16 ENST00000341223.3
CFL2
cofilin 2 (muscle)
chr8_-_110346614 0.15 ENST00000239690.4
NUDCD1
NudC domain containing 1
chr1_+_154975258 0.15 ENST00000417934.2
ZBTB7B
zinc finger and BTB domain containing 7B
chr7_-_135433460 0.15 ENST00000415751.1
FAM180A
family with sequence similarity 180, member A
chr3_-_149051444 0.15 ENST00000296059.2
TM4SF18
transmembrane 4 L six family member 18
chr17_+_39411636 0.15 ENST00000394008.1
KRTAP9-9
keratin associated protein 9-9
chr6_-_113953705 0.15 ENST00000452675.1
RP11-367G18.1
RP11-367G18.1
chr4_+_79567057 0.15 ENST00000503259.1
ENST00000507802.1
RP11-792D21.2
long intergenic non-protein coding RNA 1094
chr11_-_113577014 0.14 ENST00000544634.1
ENST00000539732.1
ENST00000538770.1
ENST00000536856.1
ENST00000544476.1
TMPRSS5
transmembrane protease, serine 5
chrX_-_114953669 0.14 ENST00000449327.1
RP1-241P17.4
Uncharacterized protein
chr6_-_32157947 0.14 ENST00000375050.4
PBX2
pre-B-cell leukemia homeobox 2
chr5_-_79946820 0.14 ENST00000604882.1
MTRNR2L2
MT-RNR2-like 2
chr4_+_79567314 0.14 ENST00000503539.1
ENST00000504675.1
RP11-792D21.2
long intergenic non-protein coding RNA 1094
chr3_+_137906154 0.14 ENST00000466749.1
ENST00000358441.2
ENST00000489213.1
ARMC8
armadillo repeat containing 8
chr16_+_57680043 0.14 ENST00000569154.1
GPR56
G protein-coupled receptor 56
chrX_-_133792480 0.14 ENST00000359237.4
PLAC1
placenta-specific 1
chr1_+_42922173 0.14 ENST00000455780.1
ENST00000372560.3
ENST00000372561.3
ENST00000372556.3
PPCS
phosphopantothenoylcysteine synthetase
chr15_-_49255632 0.14 ENST00000332408.4
SHC4
SHC (Src homology 2 domain containing) family, member 4
chr11_-_10920838 0.14 ENST00000503469.2
CTD-2003C8.2
CTD-2003C8.2
chr1_+_212475148 0.13 ENST00000537030.3
PPP2R5A
protein phosphatase 2, regulatory subunit B', alpha
chr1_+_78470530 0.13 ENST00000370763.5
DNAJB4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr7_-_75241096 0.13 ENST00000420909.1
HIP1
huntingtin interacting protein 1
chr2_-_183387064 0.13 ENST00000536095.1
ENST00000331935.6
ENST00000358139.2
ENST00000456212.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr10_-_97200772 0.13 ENST00000371241.1
ENST00000354106.3
ENST00000371239.1
ENST00000361941.3
ENST00000277982.5
ENST00000371245.3
SORBS1
sorbin and SH3 domain containing 1
chr2_-_99797473 0.13 ENST00000409107.1
ENST00000289359.2
MITD1
MIT, microtubule interacting and transport, domain containing 1
chr10_+_80008505 0.12 ENST00000434974.1
ENST00000423770.1
ENST00000432742.1
LINC00856
long intergenic non-protein coding RNA 856
chr2_+_234602305 0.12 ENST00000406651.1
UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6
chr5_+_64064748 0.12 ENST00000381070.3
ENST00000508024.1
CWC27
CWC27 spliceosome-associated protein homolog (S. cerevisiae)
chr2_-_179315490 0.12 ENST00000487082.1
PRKRA
protein kinase, interferon-inducible double stranded RNA dependent activator
chr6_+_33551515 0.12 ENST00000374458.1
GGNBP1
gametogenetin binding protein 1 (pseudogene)
chr4_-_23735183 0.12 ENST00000507666.1
RP11-380P13.2
RP11-380P13.2
chr11_-_10530723 0.12 ENST00000536684.1
MTRNR2L8
MT-RNR2-like 8
chr11_+_111169565 0.12 ENST00000528846.1
COLCA2
colorectal cancer associated 2
chr4_-_71532339 0.12 ENST00000254801.4
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr2_-_216300784 0.12 ENST00000421182.1
ENST00000432072.2
ENST00000323926.6
ENST00000336916.4
ENST00000357867.4
ENST00000359671.1
ENST00000346544.3
ENST00000345488.5
ENST00000357009.2
ENST00000446046.1
ENST00000356005.4
ENST00000443816.1
ENST00000426059.1
ENST00000354785.4
FN1
fibronectin 1
chr3_+_149531607 0.12 ENST00000468648.1
ENST00000459632.1
RNF13
ring finger protein 13
chr3_+_149530836 0.11 ENST00000466478.1
ENST00000491086.1
ENST00000467977.1
RNF13
ring finger protein 13
chr4_-_87028478 0.11 ENST00000515400.1
ENST00000395157.3
MAPK10
mitogen-activated protein kinase 10
chr1_+_150229554 0.11 ENST00000369111.4
CA14
carbonic anhydrase XIV
chr19_+_13135731 0.11 ENST00000587260.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr11_+_134225909 0.11 ENST00000533324.1
GLB1L2
galactosidase, beta 1-like 2
chr6_-_76203345 0.11 ENST00000393004.2
FILIP1
filamin A interacting protein 1
chr7_+_30960915 0.11 ENST00000441328.2
ENST00000409899.1
ENST00000409611.1
AQP1
aquaporin 1 (Colton blood group)
chr6_-_10413112 0.11 ENST00000465858.1
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr1_+_1846519 0.11 ENST00000378604.3
CALML6
calmodulin-like 6
chr5_+_102201430 0.11 ENST00000438793.3
ENST00000346918.2
PAM
peptidylglycine alpha-amidating monooxygenase
chr9_-_15510989 0.11 ENST00000380715.1
ENST00000380716.4
ENST00000380738.4
ENST00000380733.4
PSIP1
PC4 and SFRS1 interacting protein 1
chr4_+_128802016 0.11 ENST00000270861.5
ENST00000515069.1
ENST00000513090.1
ENST00000507249.1
PLK4
polo-like kinase 4
chr7_+_99202003 0.11 ENST00000609449.1
GS1-259H13.2
GS1-259H13.2
chr6_-_128222103 0.11 ENST00000434358.1
ENST00000543064.1
ENST00000368248.2
THEMIS
thymocyte selection associated
chr4_+_79567233 0.11 ENST00000514130.1
RP11-792D21.2
long intergenic non-protein coding RNA 1094
chr13_+_102104980 0.11 ENST00000545560.2
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr7_-_14026123 0.11 ENST00000420159.2
ENST00000399357.3
ENST00000403527.1
ETV1
ets variant 1
chr4_-_71705027 0.11 ENST00000545193.1
GRSF1
G-rich RNA sequence binding factor 1
chr17_+_57642886 0.10 ENST00000251241.4
ENST00000451169.2
ENST00000425628.3
ENST00000584385.1
ENST00000580030.1
DHX40
DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr17_-_26903900 0.10 ENST00000395319.3
ENST00000581807.1
ENST00000584086.1
ENST00000395321.2
ALDOC
aldolase C, fructose-bisphosphate
chr4_-_105416039 0.10 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr9_+_131683174 0.10 ENST00000372592.3
ENST00000428610.1
PHYHD1
phytanoyl-CoA dioxygenase domain containing 1
chr19_+_41119794 0.10 ENST00000593463.1
LTBP4
latent transforming growth factor beta binding protein 4
chr2_-_165698521 0.10 ENST00000409184.3
ENST00000392717.2
ENST00000456693.1
COBLL1
cordon-bleu WH2 repeat protein-like 1
chr4_-_71705060 0.10 ENST00000514161.1
GRSF1
G-rich RNA sequence binding factor 1
chr2_-_179315453 0.10 ENST00000432031.2
PRKRA
protein kinase, interferon-inducible double stranded RNA dependent activator
chr2_-_165697717 0.10 ENST00000439313.1
COBLL1
cordon-bleu WH2 repeat protein-like 1
chr17_-_26694979 0.09 ENST00000438614.1
VTN
vitronectin
chr6_+_167412835 0.09 ENST00000349556.4
FGFR1OP
FGFR1 oncogene partner
chr13_+_102104952 0.09 ENST00000376180.3
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr6_-_32908792 0.09 ENST00000418107.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr2_+_74361599 0.09 ENST00000401851.1
MGC10955
MGC10955
chr8_+_40010989 0.09 ENST00000315792.3
C8orf4
chromosome 8 open reading frame 4
chr4_+_14113592 0.09 ENST00000502759.1
ENST00000511200.1
ENST00000512754.1
ENST00000506739.1
LINC01085
long intergenic non-protein coding RNA 1085
chr12_+_50146747 0.09 ENST00000547798.1
TMBIM6
transmembrane BAX inhibitor motif containing 6
chr11_-_113577052 0.09 ENST00000540540.1
ENST00000545579.1
ENST00000538955.1
ENST00000299882.5
TMPRSS5
transmembrane protease, serine 5
chr7_-_129845313 0.09 ENST00000397622.2
TMEM209
transmembrane protein 209
chr2_+_191045656 0.09 ENST00000443551.2
C2orf88
chromosome 2 open reading frame 88
chr7_+_138145145 0.09 ENST00000415680.2
TRIM24
tripartite motif containing 24
chr19_+_52264449 0.09 ENST00000599326.1
ENST00000598953.1
FPR2
formyl peptide receptor 2
chr12_+_58003935 0.09 ENST00000333972.7
ARHGEF25
Rho guanine nucleotide exchange factor (GEF) 25
chr13_+_78315466 0.08 ENST00000314070.5
ENST00000462234.1
SLAIN1
SLAIN motif family, member 1
chr20_+_33589048 0.08 ENST00000446156.1
ENST00000453028.1
ENST00000435272.1
ENST00000433934.2
ENST00000456649.1
MYH7B
myosin, heavy chain 7B, cardiac muscle, beta
chr17_+_46970127 0.08 ENST00000355938.5
ATP5G1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr17_+_22022437 0.08 ENST00000540040.1
MTRNR2L1
MT-RNR2-like 1
chr8_+_82644669 0.08 ENST00000297265.4
CHMP4C
charged multivesicular body protein 4C
chr2_-_188312971 0.08 ENST00000410068.1
ENST00000447403.1
ENST00000410102.1
CALCRL
calcitonin receptor-like
chr3_+_29323043 0.08 ENST00000452462.1
ENST00000456853.1
RBMS3
RNA binding motif, single stranded interacting protein 3
chr16_+_50582222 0.08 ENST00000268459.3
NKD1
naked cuticle homolog 1 (Drosophila)
chr8_+_35649365 0.08 ENST00000437887.1
AC012215.1
Uncharacterized protein
chr22_+_38219389 0.08 ENST00000249041.2
GALR3
galanin receptor 3
chr17_+_73997796 0.08 ENST00000586261.1
CDK3
cyclin-dependent kinase 3
chr12_-_71551652 0.08 ENST00000546561.1
TSPAN8
tetraspanin 8
chr3_+_137906109 0.08 ENST00000481646.1
ENST00000469044.1
ENST00000491704.1
ENST00000461600.1
ARMC8
armadillo repeat containing 8
chr8_+_10530155 0.08 ENST00000521818.1
C8orf74
chromosome 8 open reading frame 74
chrX_+_99899180 0.08 ENST00000373004.3
SRPX2
sushi-repeat containing protein, X-linked 2
chr5_+_52776449 0.08 ENST00000396947.3
FST
follistatin
chrX_-_48328631 0.08 ENST00000429543.1
ENST00000317669.5
SLC38A5
solute carrier family 38, member 5
chr6_-_88299678 0.07 ENST00000369536.5
RARS2
arginyl-tRNA synthetase 2, mitochondrial
chr3_+_125985620 0.07 ENST00000511512.1
ENST00000512435.1
RP11-71E19.1
RP11-71E19.1
chr7_-_129845188 0.07 ENST00000462753.1
ENST00000471077.1
ENST00000473456.1
ENST00000336804.8
TMEM209
transmembrane protein 209
chr15_+_93447675 0.07 ENST00000536619.1
CHD2
chromodomain helicase DNA binding protein 2
chr3_+_137906353 0.07 ENST00000461822.1
ENST00000485396.1
ENST00000471453.1
ENST00000470821.1
ENST00000471709.1
ENST00000538260.1
ENST00000393058.3
ENST00000463485.1
ARMC8
armadillo repeat containing 8
chr20_+_23016057 0.07 ENST00000255008.3
SSTR4
somatostatin receptor 4
chr2_+_130737223 0.07 ENST00000410061.2
RAB6C
RAB6C, member RAS oncogene family
chr1_+_155829341 0.07 ENST00000539162.1
SYT11
synaptotagmin XI
chr7_+_73442487 0.07 ENST00000380575.4
ENST00000380584.4
ENST00000458204.1
ENST00000357036.5
ENST00000417091.1
ENST00000429192.1
ENST00000442310.1
ENST00000380553.4
ENST00000380576.5
ENST00000428787.1
ENST00000320399.6
ELN
elastin
chr17_+_46970178 0.07 ENST00000393366.2
ENST00000506855.1
ATP5G1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr10_-_114206649 0.07 ENST00000369404.3
ENST00000369405.3
ZDHHC6
zinc finger, DHHC-type containing 6
chr5_+_102201687 0.07 ENST00000304400.7
PAM
peptidylglycine alpha-amidating monooxygenase
chr2_-_61244308 0.07 ENST00000407787.1
ENST00000398658.2
PUS10
pseudouridylate synthase 10
chrX_+_109602039 0.07 ENST00000520821.1
RGAG1
retrotransposon gag domain containing 1
chr7_+_130126165 0.07 ENST00000427521.1
ENST00000416162.2
ENST00000378576.4
MEST
mesoderm specific transcript
chr10_+_94352956 0.07 ENST00000260731.3
KIF11
kinesin family member 11
chr4_+_177241094 0.07 ENST00000503362.1
SPCS3
signal peptidase complex subunit 3 homolog (S. cerevisiae)
chr12_+_7456880 0.07 ENST00000399422.4
ACSM4
acyl-CoA synthetase medium-chain family member 4
chrX_-_48328551 0.06 ENST00000376876.3
SLC38A5
solute carrier family 38, member 5
chr12_+_79258547 0.06 ENST00000457153.2
SYT1
synaptotagmin I
chr17_-_4463856 0.06 ENST00000574584.1
ENST00000381550.3
ENST00000301395.3
GGT6
gamma-glutamyltransferase 6
chr17_-_26697304 0.06 ENST00000536498.1
VTN
vitronectin
chr12_+_56473628 0.06 ENST00000549282.1
ENST00000549061.1
ENST00000267101.3
ERBB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr11_-_71810258 0.06 ENST00000544594.1
LAMTOR1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
chr5_+_102201509 0.06 ENST00000348126.2
ENST00000379787.4
PAM
peptidylglycine alpha-amidating monooxygenase
chr2_-_183387430 0.06 ENST00000410103.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr11_-_10920714 0.06 ENST00000533941.1
CTD-2003C8.2
CTD-2003C8.2
chr19_-_42947121 0.06 ENST00000601181.1
CXCL17
chemokine (C-X-C motif) ligand 17
chrX_+_9880590 0.06 ENST00000452575.1
SHROOM2
shroom family member 2
chr17_+_38119216 0.06 ENST00000301659.4
GSDMA
gasdermin A
chr18_+_29171689 0.06 ENST00000237014.3
TTR
transthyretin
chr7_-_37026108 0.06 ENST00000396045.3
ELMO1
engulfment and cell motility 1
chr2_-_158182105 0.06 ENST00000409925.1
ERMN
ermin, ERM-like protein
chr20_-_60573188 0.06 ENST00000474089.1
TAF4
TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
chr19_+_42254885 0.06 ENST00000595740.1
CEACAM6
carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
chr8_-_26371608 0.06 ENST00000522362.2
PNMA2
paraneoplastic Ma antigen 2
chr1_+_204494618 0.06 ENST00000367180.1
ENST00000391947.2
MDM4
Mdm4 p53 binding protein homolog (mouse)
chr17_-_42988004 0.06 ENST00000586125.1
ENST00000591880.1
GFAP
glial fibrillary acidic protein
chr1_+_154975110 0.06 ENST00000535420.1
ENST00000368426.3
ZBTB7B
zinc finger and BTB domain containing 7B
chr1_+_202183200 0.05 ENST00000439764.2
LGR6
leucine-rich repeat containing G protein-coupled receptor 6
chr1_+_192778161 0.05 ENST00000235382.5
RGS2
regulator of G-protein signaling 2, 24kDa
chr2_+_64681219 0.05 ENST00000238875.5
LGALSL
lectin, galactoside-binding-like
chr3_+_44626359 0.05 ENST00000412641.1
ZNF197
zinc finger protein 197
chr7_+_130126012 0.05 ENST00000341441.5
MEST
mesoderm specific transcript
chr17_+_41150290 0.05 ENST00000589037.1
ENST00000253788.5
RPL27
ribosomal protein L27
chr11_-_17229480 0.05 ENST00000532035.1
ENST00000540361.1
PIK3C2A
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
chr17_+_46970134 0.05 ENST00000503641.1
ENST00000514808.1
ATP5G1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr1_-_145039771 0.05 ENST00000493130.2
ENST00000532801.1
ENST00000478649.2
PDE4DIP
phosphodiesterase 4D interacting protein
chr21_+_17791648 0.05 ENST00000602892.1
ENST00000418813.2
ENST00000435697.1
LINC00478
long intergenic non-protein coding RNA 478
chr1_-_166944652 0.05 ENST00000528703.1
ENST00000525740.1
ENST00000529387.1
ENST00000469934.2
ENST00000529071.1
ENST00000526687.1
ILDR2
immunoglobulin-like domain containing receptor 2
chr5_-_76935513 0.05 ENST00000306422.3
OTP
orthopedia homeobox
chr5_-_148442584 0.05 ENST00000394358.2
ENST00000512049.1
SH3TC2
SH3 domain and tetratricopeptide repeats 2

Network of associatons between targets according to the STRING database.

First level regulatory network of PGR

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.1 0.2 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.1 0.2 GO:1901143 insulin catabolic process(GO:1901143)
0.1 0.2 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.1 0.2 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.0 0.3 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 0.2 GO:0002384 hepatic immune response(GO:0002384) response to prolactin(GO:1990637)
0.0 0.1 GO:2000588 positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588)
0.0 0.2 GO:2000329 peptidyl-lysine oxidation(GO:0018057) negative regulation of T-helper 17 cell lineage commitment(GO:2000329)
0.0 0.1 GO:1904237 regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237)
0.0 0.1 GO:0030185 nitric oxide transport(GO:0030185) carbon dioxide transmembrane transport(GO:0035378)
0.0 0.2 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 0.1 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.0 0.1 GO:0008057 eye pigment granule organization(GO:0008057)
0.0 0.2 GO:2000537 regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.0 0.4 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.3 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.5 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.0 0.2 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.1 GO:1990927 calcium ion regulated lysosome exocytosis(GO:1990927)
0.0 0.1 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.0 0.1 GO:0003409 optic cup structural organization(GO:0003409) oculomotor nerve morphogenesis(GO:0021622) oculomotor nerve formation(GO:0021623)
0.0 0.4 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.3 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.1 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.0 0.1 GO:0018032 protein amidation(GO:0018032)
0.0 0.5 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.1 GO:0060620 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0 0.1 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.0 0.2 GO:0050957 equilibrioception(GO:0050957)
0.0 0.4 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 0.0 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.1 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.2 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.1 GO:1904714 chaperone-mediated autophagy(GO:0061684) regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.3 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.0 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.0 0.1 GO:0031438 negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.0 0.0 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812) B cell cytokine production(GO:0002368)
0.0 0.2 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.0 GO:0060699 regulation of endoribonuclease activity(GO:0060699)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:0010446 response to alkaline pH(GO:0010446)
0.0 0.3 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.1 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.1 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.0 0.1 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0 0.2 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.0 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) glomerular endothelium development(GO:0072011) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.0 0.2 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.2 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0020003 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.0 0.2 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.4 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.4 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.1 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.1 GO:0098536 deuterosome(GO:0098536)
0.0 0.2 GO:0071953 elastic fiber(GO:0071953)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.2 GO:0031597 cytosolic proteasome complex(GO:0031597)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 0.2 GO:0031626 beta-endorphin binding(GO:0031626)
0.0 0.4 GO:0070883 pre-miRNA binding(GO:0070883)
0.0 0.1 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.0 0.3 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.2 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.2 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.3 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.3 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.1 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.2 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.3 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.1 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.1 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.1 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.1 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.0 GO:0005151 interleukin-1, Type II receptor binding(GO:0005151)
0.0 0.1 GO:0015265 urea channel activity(GO:0015265)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.5 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation