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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for PDX1

Z-value: 0.70

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Transcription factors associated with PDX1

Gene Symbol Gene ID Gene Info
PDX1
ENSG00000139515.5 pancreatic and duodenal homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PDX1hg19_v2_chr13_+_28494130_28494168-0.463.5e-01Click!

Activity profile of PDX1 motif

Sorted Z-values of PDX1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_86650077 0.65 ENST00000552808.2
ENST00000547225.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr8_-_1922789 0.64 ENST00000521498.1
RP11-439C15.4
RP11-439C15.4
chr22_-_28490123 0.56 ENST00000442232.1
TTC28
tetratricopeptide repeat domain 28
chr4_+_53525573 0.52 ENST00000503051.1
USP46-AS1
USP46 antisense RNA 1
chr1_+_62439037 0.50 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr11_+_115498761 0.49 ENST00000424313.2
AP000997.1
AP000997.1
chr14_+_59100774 0.48 ENST00000556859.1
ENST00000421793.1
DACT1
dishevelled-binding antagonist of beta-catenin 1
chr2_+_66918558 0.47 ENST00000435389.1
ENST00000428590.1
ENST00000412944.1
AC007392.3
AC007392.3
chr17_+_74846230 0.46 ENST00000592919.1
LINC00868
long intergenic non-protein coding RNA 868
chr14_+_39944025 0.43 ENST00000554328.1
ENST00000556620.1
ENST00000557197.1
RP11-111A21.1
RP11-111A21.1
chr14_+_100485712 0.43 ENST00000544450.2
EVL
Enah/Vasp-like
chr14_-_77889860 0.39 ENST00000555603.1
NOXRED1
NADP-dependent oxidoreductase domain containing 1
chr3_-_112127981 0.37 ENST00000486726.2
RP11-231E6.1
RP11-231E6.1
chr17_-_8301132 0.36 ENST00000399398.2
RNF222
ring finger protein 222
chr1_-_159832438 0.35 ENST00000368100.1
VSIG8
V-set and immunoglobulin domain containing 8
chr4_+_22999152 0.35 ENST00000511453.1
RP11-412P11.1
RP11-412P11.1
chr2_+_45168875 0.34 ENST00000260653.3
SIX3
SIX homeobox 3
chr11_-_8285405 0.34 ENST00000335790.3
ENST00000534484.1
LMO1
LIM domain only 1 (rhombotin 1)
chr1_-_219615984 0.32 ENST00000420762.1
RP11-95P13.1
RP11-95P13.1
chr5_+_66300464 0.32 ENST00000436277.1
MAST4
microtubule associated serine/threonine kinase family member 4
chr15_+_59910132 0.31 ENST00000559200.1
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr15_+_75080883 0.28 ENST00000567571.1
CSK
c-src tyrosine kinase
chr12_+_107712173 0.28 ENST00000280758.5
ENST00000420571.2
BTBD11
BTB (POZ) domain containing 11
chrX_+_10031499 0.28 ENST00000454666.1
WWC3
WWC family member 3
chr6_-_116833500 0.27 ENST00000356128.4
TRAPPC3L
trafficking protein particle complex 3-like
chr17_-_2117600 0.27 ENST00000572369.1
SMG6
SMG6 nonsense mediated mRNA decay factor
chr7_-_99716914 0.26 ENST00000431404.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr13_-_46716969 0.26 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr17_-_77924627 0.26 ENST00000572862.1
ENST00000573782.1
ENST00000574427.1
ENST00000570373.1
ENST00000340848.7
ENST00000576768.1
TBC1D16
TBC1 domain family, member 16
chr20_-_50418947 0.25 ENST00000371539.3
SALL4
spalt-like transcription factor 4
chr9_+_131037623 0.25 ENST00000495313.1
ENST00000372898.2
SWI5
SWI5 recombination repair homolog (yeast)
chr20_+_60174827 0.25 ENST00000543233.1
CDH4
cadherin 4, type 1, R-cadherin (retinal)
chr4_+_169013666 0.24 ENST00000359299.3
ANXA10
annexin A10
chr7_-_111424462 0.23 ENST00000437129.1
DOCK4
dedicator of cytokinesis 4
chr2_-_112237835 0.22 ENST00000442293.1
ENST00000439494.1
MIR4435-1HG
MIR4435-1 host gene (non-protein coding)
chr6_-_31107127 0.22 ENST00000259845.4
PSORS1C2
psoriasis susceptibility 1 candidate 2
chr8_+_77593474 0.22 ENST00000455469.2
ENST00000050961.6
ZFHX4
zinc finger homeobox 4
chr10_+_24497704 0.22 ENST00000376456.4
ENST00000458595.1
KIAA1217
KIAA1217
chr2_-_8715616 0.21 ENST00000418358.1
AC011747.3
AC011747.3
chr8_-_37594944 0.21 ENST00000330539.1
RP11-863K10.7
Uncharacterized protein
chr4_+_146402346 0.21 ENST00000514778.1
ENST00000507594.1
SMAD1
SMAD family member 1
chr15_+_62853562 0.21 ENST00000561311.1
TLN2
talin 2
chr8_+_9953061 0.21 ENST00000522907.1
ENST00000528246.1
MSRA
methionine sulfoxide reductase A
chr14_-_92247032 0.21 ENST00000556661.1
ENST00000553676.1
ENST00000554560.1
CATSPERB
catsper channel auxiliary subunit beta
chr17_-_27467418 0.21 ENST00000528564.1
MYO18A
myosin XVIIIA
chr5_+_172068232 0.20 ENST00000520919.1
ENST00000522853.1
ENST00000369800.5
NEURL1B
neuralized E3 ubiquitin protein ligase 1B
chrX_+_10126488 0.19 ENST00000380829.1
ENST00000421085.2
ENST00000454850.1
CLCN4
chloride channel, voltage-sensitive 4
chr7_+_114055052 0.18 ENST00000462331.1
ENST00000408937.3
ENST00000403559.4
ENST00000350908.4
ENST00000393498.2
ENST00000393495.3
ENST00000378237.3
ENST00000393489.3
FOXP2
forkhead box P2
chr7_+_129015484 0.18 ENST00000490911.1
AHCYL2
adenosylhomocysteinase-like 2
chr7_-_111424506 0.18 ENST00000450156.1
ENST00000494651.2
DOCK4
dedicator of cytokinesis 4
chr15_-_37393406 0.18 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
MEIS2
Meis homeobox 2
chr17_+_72427477 0.17 ENST00000342648.5
ENST00000481232.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr16_+_53133070 0.17 ENST00000565832.1
CHD9
chromodomain helicase DNA binding protein 9
chr4_-_139163491 0.17 ENST00000280612.5
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr19_-_56110859 0.17 ENST00000221665.3
ENST00000592585.1
FIZ1
FLT3-interacting zinc finger 1
chr9_-_13165457 0.17 ENST00000542239.1
ENST00000538841.1
ENST00000433359.2
MPDZ
multiple PDZ domain protein
chr14_+_61654271 0.17 ENST00000555185.1
ENST00000557294.1
ENST00000556778.1
PRKCH
protein kinase C, eta
chr2_+_87769459 0.16 ENST00000414030.1
ENST00000437561.1
LINC00152
long intergenic non-protein coding RNA 152
chrX_-_21676442 0.16 ENST00000379499.2
KLHL34
kelch-like family member 34
chr8_+_77593448 0.16 ENST00000521891.2
ZFHX4
zinc finger homeobox 4
chr8_+_9953214 0.16 ENST00000382490.5
MSRA
methionine sulfoxide reductase A
chr5_+_137722255 0.16 ENST00000542866.1
KDM3B
lysine (K)-specific demethylase 3B
chr14_-_95236551 0.16 ENST00000238558.3
GSC
goosecoid homeobox
chr20_-_50419055 0.16 ENST00000217086.4
SALL4
spalt-like transcription factor 4
chr20_-_56286479 0.15 ENST00000265626.4
PMEPA1
prostate transmembrane protein, androgen induced 1
chr3_+_69985734 0.15 ENST00000314557.6
ENST00000394351.3
MITF
microphthalmia-associated transcription factor
chr1_+_28586006 0.15 ENST00000253063.3
SESN2
sestrin 2
chr17_-_18430160 0.15 ENST00000392176.3
FAM106A
family with sequence similarity 106, member A
chr15_+_59279851 0.15 ENST00000348370.4
ENST00000434298.1
ENST00000559160.1
RNF111
ring finger protein 111
chr15_+_41913690 0.14 ENST00000563576.1
MGA
MGA, MAX dimerization protein
chr17_-_71223839 0.14 ENST00000579872.1
ENST00000580032.1
FAM104A
family with sequence similarity 104, member A
chr1_+_212965170 0.14 ENST00000532324.1
ENST00000366974.4
ENST00000530441.1
ENST00000526641.1
ENST00000531963.1
ENST00000366973.4
ENST00000526997.1
ENST00000488246.2
TATDN3
TatD DNase domain containing 3
chr16_-_30457048 0.14 ENST00000500504.2
ENST00000542752.1
SEPHS2
selenophosphate synthetase 2
chr8_+_22844995 0.14 ENST00000524077.1
RHOBTB2
Rho-related BTB domain containing 2
chrX_-_100129128 0.14 ENST00000372960.4
ENST00000372964.1
ENST00000217885.5
NOX1
NADPH oxidase 1
chr18_-_46784778 0.14 ENST00000582399.1
DYM
dymeclin
chr7_+_100860949 0.13 ENST00000305105.2
ZNHIT1
zinc finger, HIT-type containing 1
chr12_-_56321397 0.13 ENST00000557259.1
ENST00000549939.1
WIBG
within bgcn homolog (Drosophila)
chr4_-_103749179 0.13 ENST00000502690.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr5_-_36301984 0.13 ENST00000502994.1
ENST00000515759.1
ENST00000296604.3
RANBP3L
RAN binding protein 3-like
chr11_-_129062093 0.13 ENST00000310343.9
ARHGAP32
Rho GTPase activating protein 32
chr6_+_13272904 0.12 ENST00000379335.3
ENST00000379329.1
PHACTR1
phosphatase and actin regulator 1
chr1_+_198608146 0.12 ENST00000367376.2
ENST00000352140.3
ENST00000594404.1
ENST00000598951.1
ENST00000530727.1
ENST00000442510.2
ENST00000367367.4
ENST00000348564.6
ENST00000367364.1
ENST00000413409.2
PTPRC
protein tyrosine phosphatase, receptor type, C
chr13_-_99667960 0.12 ENST00000448493.2
DOCK9
dedicator of cytokinesis 9
chr10_+_24738355 0.12 ENST00000307544.6
KIAA1217
KIAA1217
chr11_+_130318869 0.12 ENST00000299164.2
ADAMTS15
ADAM metallopeptidase with thrombospondin type 1 motif, 15
chr3_-_98235962 0.12 ENST00000513873.1
CLDND1
claudin domain containing 1
chr4_-_41884620 0.12 ENST00000504870.1
LINC00682
long intergenic non-protein coding RNA 682
chr1_+_19967014 0.12 ENST00000428975.1
NBL1
neuroblastoma 1, DAN family BMP antagonist
chr5_+_98109322 0.12 ENST00000513185.1
RGMB
repulsive guidance molecule family member b
chr5_-_140998481 0.11 ENST00000518047.1
DIAPH1
diaphanous-related formin 1
chr17_-_39623681 0.11 ENST00000225899.3
KRT32
keratin 32
chr12_+_64798826 0.11 ENST00000540203.1
XPOT
exportin, tRNA
chr8_+_38831683 0.10 ENST00000302495.4
HTRA4
HtrA serine peptidase 4
chr9_-_117267717 0.10 ENST00000374057.3
DFNB31
deafness, autosomal recessive 31
chr9_-_123639600 0.10 ENST00000373896.3
PHF19
PHD finger protein 19
chr6_-_33160231 0.10 ENST00000395194.1
ENST00000457788.1
ENST00000341947.2
ENST00000357486.1
ENST00000374714.1
ENST00000374713.1
ENST00000395197.1
ENST00000374712.1
ENST00000361917.1
ENST00000374708.4
COL11A2
collagen, type XI, alpha 2
chr7_-_100860851 0.10 ENST00000223127.3
PLOD3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chrX_+_7137475 0.10 ENST00000217961.4
STS
steroid sulfatase (microsomal), isozyme S
chr17_-_33446735 0.10 ENST00000460118.2
ENST00000335858.7
RAD51D
RAD51 paralog D
chr7_-_99717463 0.10 ENST00000437822.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr5_+_66300446 0.10 ENST00000261569.7
MAST4
microtubule associated serine/threonine kinase family member 4
chr1_-_94147385 0.09 ENST00000260502.6
BCAR3
breast cancer anti-estrogen resistance 3
chr2_+_109204743 0.09 ENST00000332345.6
LIMS1
LIM and senescent cell antigen-like domains 1
chr4_-_119759795 0.09 ENST00000419654.2
SEC24D
SEC24 family member D
chr2_+_96331830 0.09 ENST00000425887.2
AC008268.1
AC008268.1
chr4_+_141445333 0.09 ENST00000507667.1
ELMOD2
ELMO/CED-12 domain containing 2
chr4_+_144354644 0.09 ENST00000512843.1
GAB1
GRB2-associated binding protein 1
chr3_+_69985792 0.09 ENST00000531774.1
MITF
microphthalmia-associated transcription factor
chr5_-_140998616 0.09 ENST00000389054.3
ENST00000398562.2
ENST00000389057.5
ENST00000398566.3
ENST00000398557.4
ENST00000253811.6
DIAPH1
diaphanous-related formin 1
chr15_+_69854027 0.09 ENST00000498938.2
RP11-279F6.1
RP11-279F6.1
chr2_-_208031943 0.09 ENST00000421199.1
ENST00000457962.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr1_-_232651312 0.09 ENST00000262861.4
SIPA1L2
signal-induced proliferation-associated 1 like 2
chr14_-_69261310 0.09 ENST00000336440.3
ZFP36L1
ZFP36 ring finger protein-like 1
chr1_-_151431647 0.08 ENST00000368863.2
ENST00000409503.1
ENST00000491586.1
ENST00000533351.1
ENST00000540984.1
POGZ
pogo transposable element with ZNF domain
chr10_-_21806759 0.08 ENST00000444772.3
SKIDA1
SKI/DACH domain containing 1
chr15_-_72563585 0.08 ENST00000287196.9
ENST00000260376.7
PARP6
poly (ADP-ribose) polymerase family, member 6
chr1_-_1710229 0.08 ENST00000341991.3
NADK
NAD kinase
chr13_-_67802549 0.08 ENST00000328454.5
ENST00000377865.2
PCDH9
protocadherin 9
chr20_-_31124186 0.08 ENST00000375678.3
C20orf112
chromosome 20 open reading frame 112
chr12_-_56321649 0.08 ENST00000454792.2
ENST00000408946.2
WIBG
within bgcn homolog (Drosophila)
chrX_-_19817869 0.08 ENST00000379698.4
SH3KBP1
SH3-domain kinase binding protein 1
chr7_+_129015671 0.08 ENST00000466993.1
AHCYL2
adenosylhomocysteinase-like 2
chr8_+_22844913 0.08 ENST00000519685.1
RHOBTB2
Rho-related BTB domain containing 2
chr4_+_77356248 0.08 ENST00000296043.6
SHROOM3
shroom family member 3
chr15_-_34875771 0.08 ENST00000267731.7
GOLGA8B
golgin A8 family, member B
chr20_-_271304 0.08 ENST00000400269.3
ENST00000360321.2
C20orf96
chromosome 20 open reading frame 96
chr1_-_151431909 0.08 ENST00000361398.3
ENST00000271715.2
POGZ
pogo transposable element with ZNF domain
chr20_+_43538692 0.08 ENST00000217074.4
ENST00000255136.3
PABPC1L
poly(A) binding protein, cytoplasmic 1-like
chr17_-_9929581 0.08 ENST00000437099.2
ENST00000396115.2
GAS7
growth arrest-specific 7
chr2_+_191208656 0.07 ENST00000458647.1
INPP1
inositol polyphosphate-1-phosphatase
chr19_-_12889226 0.07 ENST00000589400.1
ENST00000590839.1
ENST00000592079.1
HOOK2
hook microtubule-tethering protein 2
chr11_-_31531121 0.07 ENST00000532287.1
ENST00000526776.1
ENST00000534812.1
ENST00000529749.1
ENST00000278200.1
ENST00000530023.1
ENST00000533642.1
IMMP1L
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chrX_-_106146547 0.07 ENST00000276173.4
ENST00000411805.1
RIPPLY1
ripply transcriptional repressor 1
chr17_-_57229155 0.07 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr9_-_136933615 0.07 ENST00000371834.2
BRD3
bromodomain containing 3
chr8_-_37457350 0.07 ENST00000519691.1
RP11-150O12.3
RP11-150O12.3
chr15_-_55562479 0.07 ENST00000564609.1
RAB27A
RAB27A, member RAS oncogene family
chr1_-_1709845 0.07 ENST00000341426.5
ENST00000344463.4
NADK
NAD kinase
chr3_-_39321512 0.07 ENST00000399220.2
CX3CR1
chemokine (C-X3-C motif) receptor 1
chr9_-_123639304 0.07 ENST00000436309.1
PHF19
PHD finger protein 19
chr5_-_134735568 0.07 ENST00000510038.1
ENST00000304332.4
H2AFY
H2A histone family, member Y
chr5_+_174151536 0.07 ENST00000239243.6
ENST00000507785.1
MSX2
msh homeobox 2
chr7_+_116660246 0.06 ENST00000434836.1
ENST00000393443.1
ENST00000465133.1
ENST00000477742.1
ENST00000393447.4
ENST00000393444.3
ST7
suppression of tumorigenicity 7
chr14_-_78083112 0.06 ENST00000216484.2
SPTLC2
serine palmitoyltransferase, long chain base subunit 2
chr8_-_131399110 0.06 ENST00000521426.1
ASAP1
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
chr15_+_91416092 0.06 ENST00000559353.1
FURIN
furin (paired basic amino acid cleaving enzyme)
chr15_-_65407524 0.06 ENST00000559089.1
UBAP1L
ubiquitin associated protein 1-like
chr20_-_50418972 0.06 ENST00000395997.3
SALL4
spalt-like transcription factor 4
chr7_-_99716952 0.06 ENST00000523306.1
ENST00000344095.4
ENST00000417349.1
ENST00000493322.1
ENST00000520135.1
ENST00000418432.2
ENST00000460673.2
ENST00000452041.1
ENST00000452438.2
ENST00000451699.1
ENST00000453269.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr12_+_15699286 0.06 ENST00000442921.2
ENST00000542557.1
ENST00000445537.2
ENST00000544244.1
PTPRO
protein tyrosine phosphatase, receptor type, O
chr12_-_109221160 0.06 ENST00000326470.5
SSH1
slingshot protein phosphatase 1
chr18_+_3447572 0.06 ENST00000548489.2
TGIF1
TGFB-induced factor homeobox 1
chr1_+_36621174 0.06 ENST00000429533.2
MAP7D1
MAP7 domain containing 1
chr12_+_47610315 0.06 ENST00000548348.1
ENST00000549500.1
PCED1B
PC-esterase domain containing 1B
chr1_+_174844645 0.06 ENST00000486220.1
RABGAP1L
RAB GTPase activating protein 1-like
chrX_-_13835147 0.06 ENST00000493677.1
ENST00000355135.2
GPM6B
glycoprotein M6B
chr4_+_71587669 0.06 ENST00000381006.3
ENST00000226328.4
RUFY3
RUN and FYVE domain containing 3
chr3_-_121740969 0.05 ENST00000393631.1
ENST00000273691.3
ENST00000344209.5
ILDR1
immunoglobulin-like domain containing receptor 1
chr5_-_142780280 0.05 ENST00000424646.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr15_-_100882191 0.05 ENST00000268070.4
ADAMTS17
ADAM metallopeptidase with thrombospondin type 1 motif, 17
chr4_-_109541610 0.05 ENST00000510212.1
RPL34-AS1
RPL34 antisense RNA 1 (head to head)
chr5_-_115890554 0.05 ENST00000509665.1
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr11_-_85430163 0.05 ENST00000529581.1
ENST00000533577.1
SYTL2
synaptotagmin-like 2
chrX_-_46187069 0.05 ENST00000446884.1
RP1-30G7.2
RP1-30G7.2
chr12_-_57328187 0.05 ENST00000293502.1
SDR9C7
short chain dehydrogenase/reductase family 9C, member 7
chr2_+_48541776 0.05 ENST00000413569.1
ENST00000340553.3
FOXN2
forkhead box N2
chr4_+_151503077 0.05 ENST00000317605.4
MAB21L2
mab-21-like 2 (C. elegans)
chr15_+_28624878 0.05 ENST00000450328.2
GOLGA8F
golgin A8 family, member F
chr20_+_43538756 0.05 ENST00000537323.1
ENST00000217073.2
PABPC1L
poly(A) binding protein, cytoplasmic 1-like
chr1_-_151431674 0.05 ENST00000531094.1
POGZ
pogo transposable element with ZNF domain
chr9_-_123639445 0.04 ENST00000312189.6
PHF19
PHD finger protein 19
chr8_+_22424551 0.04 ENST00000523348.1
SORBS3
sorbin and SH3 domain containing 3
chr12_-_86650045 0.04 ENST00000604798.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr18_+_29027696 0.04 ENST00000257189.4
DSG3
desmoglein 3
chr10_-_21186144 0.04 ENST00000377119.1
NEBL
nebulette
chr12_-_56106060 0.04 ENST00000452168.2
ITGA7
integrin, alpha 7
chr15_+_67841330 0.04 ENST00000354498.5
MAP2K5
mitogen-activated protein kinase kinase 5
chr1_-_2458026 0.04 ENST00000435556.3
ENST00000378466.3
PANK4
pantothenate kinase 4
chr1_-_234667504 0.04 ENST00000421207.1
ENST00000435574.1
RP5-855F14.1
RP5-855F14.1
chr12_-_51611477 0.04 ENST00000389243.4
POU6F1
POU class 6 homeobox 1
chr15_+_93443419 0.04 ENST00000557381.1
ENST00000420239.2
CHD2
chromodomain helicase DNA binding protein 2
chr1_+_151735431 0.04 ENST00000321531.5
ENST00000315067.8
OAZ3
ornithine decarboxylase antizyme 3
chr3_+_35722487 0.04 ENST00000441454.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr7_-_73038867 0.04 ENST00000313375.3
ENST00000354613.1
ENST00000395189.1
ENST00000453275.1
MLXIPL
MLX interacting protein-like
chr1_+_84609944 0.04 ENST00000370685.3
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr4_-_152147579 0.04 ENST00000304527.4
ENST00000455740.1
ENST00000424281.1
ENST00000409598.4
SH3D19
SH3 domain containing 19
chr12_-_32908809 0.04 ENST00000324868.8
YARS2
tyrosyl-tRNA synthetase 2, mitochondrial
chr4_-_70518941 0.03 ENST00000286604.4
ENST00000505512.1
ENST00000514019.1
UGT2A1
UGT2A1
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
chr4_-_66536057 0.03 ENST00000273854.3
EPHA5
EPH receptor A5
chr5_+_156712372 0.03 ENST00000541131.1
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr11_-_85430088 0.03 ENST00000533057.1
ENST00000533892.1
SYTL2
synaptotagmin-like 2
chr9_-_136933134 0.03 ENST00000303407.7
BRD3
bromodomain containing 3
chr20_+_43990576 0.03 ENST00000372727.1
ENST00000414310.1
SYS1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr7_-_99716940 0.03 ENST00000440225.1
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr15_-_55563072 0.03 ENST00000567380.1
ENST00000565972.1
ENST00000569493.1
RAB27A
RAB27A, member RAS oncogene family
chr18_+_32558208 0.03 ENST00000436190.2
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr6_+_43968306 0.03 ENST00000442114.2
ENST00000336600.5
ENST00000439969.2
C6orf223
chromosome 6 open reading frame 223
chr9_+_131062367 0.03 ENST00000601297.1
AL359091.2
CDNA: FLJ21673 fis, clone COL09042; HCG2036511; Uncharacterized protein
chr3_-_141747950 0.03 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)

Network of associatons between targets according to the STRING database.

First level regulatory network of PDX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0014016 neuroblast differentiation(GO:0014016)
0.1 0.3 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.1 0.3 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.1 0.5 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.1 0.2 GO:1903028 positive regulation of opsonization(GO:1903028)
0.1 0.4 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.4 GO:0006561 proline biosynthetic process(GO:0006561)
0.0 0.1 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.0 0.2 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.2 GO:1904502 regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.0 0.3 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.1 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.0 0.1 GO:0051795 positive regulation of catagen(GO:0051795)
0.0 0.4 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.2 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.0 0.3 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.4 GO:0030091 protein repair(GO:0030091)
0.0 0.5 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.1 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.1 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.0 0.1 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
0.0 0.1 GO:1904815 negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
0.0 0.1 GO:0032904 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.0 0.1 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.3 GO:0000730 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.1 GO:0035701 immunoglobulin biosynthetic process(GO:0002378) hematopoietic stem cell migration(GO:0035701) bone marrow development(GO:0048539)
0.0 0.1 GO:0098976 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.0 0.3 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.2 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.1 GO:1901545 cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545)
0.0 0.2 GO:0034350 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.0 0.2 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.3 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.4 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.2 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.2 GO:0072718 response to cisplatin(GO:0072718)
0.0 0.3 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.0 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 0.1 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.1 0.3 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.2 GO:0036128 CatSper complex(GO:0036128)
0.0 0.5 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.5 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.3 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.1 GO:0033061 DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.1 0.7 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.4 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 0.4 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1 0.5 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.0 0.2 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.3 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.1 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) procollagen galactosyltransferase activity(GO:0050211)
0.0 0.5 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.2 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.1 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
0.0 0.1 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 0.4 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.0 0.3 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.0 GO:0072545 tyrosine binding(GO:0072545)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0016015 morphogen activity(GO:0016015)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.4 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains