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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for PBX1

Z-value: 0.98

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Transcription factors associated with PBX1

Gene Symbol Gene ID Gene Info
ENSG00000185630.14 PBX homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PBX1hg19_v2_chr1_+_164600184_164600218-0.815.0e-02Click!

Activity profile of PBX1 motif

Sorted Z-values of PBX1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_38821373 1.21 ENST00000394052.3
keratin 222
chr7_-_92747269 1.14 ENST00000446617.1
ENST00000379958.2
sterile alpha motif domain containing 9
chr3_-_129375556 0.93 ENST00000510323.1
transmembrane and coiled-coil domain family 1
chr18_+_44526786 0.85 ENST00000245121.5
ENST00000356157.7
katanin p60 subunit A-like 2
chrM_+_4431 0.83 ENST00000361453.3
mitochondrially encoded NADH dehydrogenase 2
chr6_+_27114861 0.83 ENST00000377459.1
histone cluster 1, H2ah
chr10_+_63422695 0.76 ENST00000330194.2
ENST00000389639.3
chromosome 10 open reading frame 107
chrM_+_14741 0.69 ENST00000361789.2
mitochondrially encoded cytochrome b
chr12_+_21679220 0.64 ENST00000256969.2
chromosome 12 open reading frame 39
chr16_-_63651939 0.56 ENST00000563855.1
ENST00000568932.1
ENST00000564290.1
RP11-368L12.1
chr22_+_50981079 0.52 ENST00000609268.1
CTA-384D8.34
chr13_-_48612067 0.50 ENST00000543413.1
succinate-CoA ligase, ADP-forming, beta subunit
chr5_+_65440032 0.48 ENST00000334121.6
splicing regulatory glutamine/lysine-rich protein 1
chr5_+_162864575 0.47 ENST00000512163.1
ENST00000393929.1
ENST00000340828.2
ENST00000511683.2
ENST00000510097.1
ENST00000511490.2
ENST00000510664.1
cyclin G1
chrM_-_14670 0.45 ENST00000361681.2
mitochondrially encoded NADH dehydrogenase 6
chr10_-_5638048 0.45 ENST00000478294.1
RP13-463N16.6
chr7_+_7196565 0.41 ENST00000429911.1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr1_-_238108575 0.41 ENST00000604646.1
MT-RNR2-like 11 (pseudogene)
chr8_-_42360015 0.40 ENST00000522707.1
solute carrier family 20 (phosphate transporter), member 2
chrM_+_9207 0.39 ENST00000362079.2
mitochondrially encoded cytochrome c oxidase III
chr11_+_95523621 0.38 ENST00000325542.5
ENST00000325486.5
ENST00000544522.1
ENST00000541365.1
centrosomal protein 57kDa
chr4_+_26324474 0.38 ENST00000514675.1
recombination signal binding protein for immunoglobulin kappa J region
chr17_+_58018269 0.38 ENST00000591035.1
Uncharacterized protein
chr4_+_83956237 0.37 ENST00000264389.2
COP9 signalosome subunit 4
chr12_+_21654714 0.37 ENST00000542038.1
ENST00000540141.1
ENST00000229314.5
golgi transport 1B
chr11_+_44117219 0.36 ENST00000532479.1
ENST00000527014.1
exostosin glycosyltransferase 2
chr14_+_38033252 0.35 ENST00000554829.1
RP11-356O9.1
chr10_-_18948208 0.35 ENST00000607346.1
ARL5B antisense RNA 1
chr9_-_88356789 0.35 ENST00000357081.3
ENST00000376081.4
ENST00000337006.4
ENST00000376109.3
ATP/GTP binding protein 1
chr4_+_83956312 0.35 ENST00000509317.1
ENST00000503682.1
ENST00000511653.1
COP9 signalosome subunit 4
chr7_+_120629653 0.35 ENST00000450913.2
ENST00000340646.5
cadherin-like and PC-esterase domain containing 1
chr14_-_64846033 0.34 ENST00000556556.1
CTD-2555O16.1
chr3_-_149510553 0.34 ENST00000462519.2
ENST00000446160.1
ENST00000383050.3
ankyrin repeat and ubiquitin domain containing 1
chr21_-_35014027 0.33 ENST00000399442.1
ENST00000413017.2
ENST00000445393.1
ENST00000417979.1
ENST00000426935.1
ENST00000381540.3
ENST00000361534.2
ENST00000381554.3
crystallin, zeta (quinone reductase)-like 1
chr7_+_23637763 0.33 ENST00000410069.1
coiled-coil domain containing 126
chr17_-_26694979 0.32 ENST00000438614.1
vitronectin
chr16_+_50059182 0.32 ENST00000562576.1
CTD nuclear envelope phosphatase 1 regulatory subunit 1
chr5_-_86708670 0.32 ENST00000504878.1
cyclin H
chr13_+_97928395 0.31 ENST00000445661.2
muscleblind-like splicing regulator 2
chr12_+_41136144 0.30 ENST00000548005.1
ENST00000552248.1
contactin 1
chr12_+_79258444 0.30 ENST00000261205.4
synaptotagmin I
chr9_+_106856831 0.29 ENST00000303219.8
ENST00000374787.3
structural maintenance of chromosomes 2
chr2_+_201997595 0.29 ENST00000470178.2
CASP8 and FADD-like apoptosis regulator
chr5_-_133702761 0.28 ENST00000521118.1
ENST00000265334.4
ENST00000435211.1
cyclin-dependent kinase-like 3
chr2_+_12857015 0.28 ENST00000155926.4
tribbles pseudokinase 2
chr6_+_27775899 0.27 ENST00000358739.3
histone cluster 1, H2ai
chr12_+_20968608 0.27 ENST00000381541.3
ENST00000540229.1
ENST00000553473.1
ENST00000554957.1
Putative solute carrier organic anion transporter family member 1B7; Uncharacterized protein
solute carrier organic anion transporter family, member 1B3
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr19_+_33072373 0.27 ENST00000586035.1
programmed cell death 5
chr8_-_6115044 0.27 ENST00000519555.1
RP11-124B13.1
chr11_-_34937858 0.26 ENST00000278359.5
APAF1 interacting protein
chr1_+_104159999 0.26 ENST00000414303.2
ENST00000423678.1
amylase, alpha 2A (pancreatic)
chr18_+_29171689 0.26 ENST00000237014.3
transthyretin
chr4_-_105416039 0.26 ENST00000394767.2
CXXC finger protein 4
chr13_+_95254085 0.25 ENST00000376958.4
G protein-coupled receptor 180
chr6_+_99282570 0.25 ENST00000328345.5
POU class 3 homeobox 2
chr8_-_108510224 0.25 ENST00000517746.1
ENST00000297450.3
angiopoietin 1
chr11_+_95523823 0.25 ENST00000538658.1
centrosomal protein 57kDa
chr10_-_18948156 0.25 ENST00000414939.1
ENST00000449529.1
ENST00000456217.1
ENST00000444660.1
ARL5B antisense RNA 1
chr3_+_150264458 0.25 ENST00000487799.1
ENST00000460851.1
eukaryotic translation initiation factor 2A, 65kDa
chr5_-_86708833 0.25 ENST00000256897.4
cyclin H
chr11_-_2162162 0.24 ENST00000381389.1
insulin-like growth factor 2 (somatomedin A)
chr7_-_120498357 0.24 ENST00000415871.1
ENST00000222747.3
ENST00000430985.1
tetraspanin 12
chr13_-_22033392 0.24 ENST00000320220.9
ENST00000415724.1
ENST00000422251.1
ENST00000382466.3
ENST00000542645.1
ENST00000400590.3
zinc finger, DHHC-type containing 20
chr22_-_29137771 0.24 ENST00000439200.1
ENST00000405598.1
ENST00000398017.2
ENST00000425190.2
ENST00000348295.3
ENST00000382578.1
ENST00000382565.1
ENST00000382566.1
ENST00000382580.2
ENST00000328354.6
checkpoint kinase 2
chr10_+_5238793 0.23 ENST00000263126.1
aldo-keto reductase family 1, member C4
chr9_-_6015607 0.23 ENST00000259569.5
RAN binding protein 6
chr14_-_36789783 0.23 ENST00000605579.1
ENST00000604336.1
ENST00000359527.7
ENST00000603139.1
ENST00000318473.7
MAP3K12 binding inhibitory protein 1
chr5_-_132073111 0.23 ENST00000403231.1
kinesin family member 3A
chr12_-_76478686 0.22 ENST00000261182.8
nucleosome assembly protein 1-like 1
chr14_+_50065376 0.22 ENST00000298288.6
leucine rich repeat protein 1
chr6_-_26032288 0.22 ENST00000244661.2
histone cluster 1, H3b
chr4_-_70626430 0.21 ENST00000310613.3
sulfotransferase family, cytosolic, 1B, member 1
chr14_+_88851874 0.21 ENST00000393545.4
ENST00000356583.5
ENST00000555401.1
ENST00000553885.1
spermatogenesis associated 7
chr6_-_7313381 0.21 ENST00000489567.1
ENST00000479365.1
ENST00000462112.1
ENST00000397511.2
ENST00000534851.1
ENST00000474597.1
ENST00000244763.4
signal sequence receptor, alpha
chr3_+_150264555 0.21 ENST00000406576.3
ENST00000482093.1
ENST00000273435.5
eukaryotic translation initiation factor 2A, 65kDa
chr19_-_58400148 0.21 ENST00000595048.1
ENST00000600634.1
ENST00000595295.1
ENST00000596604.1
ENST00000597342.1
ENST00000597807.1
zinc finger protein 814
chr11_-_34938039 0.21 ENST00000395787.3
APAF1 interacting protein
chrX_+_92929192 0.20 ENST00000332647.4
family with sequence similarity 133, member A
chr4_-_70080449 0.20 ENST00000446444.1
UDP glucuronosyltransferase 2 family, polypeptide B11
chrM_+_10053 0.20 ENST00000361227.2
mitochondrially encoded NADH dehydrogenase 3
chr4_+_69962185 0.20 ENST00000305231.7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr2_+_201997492 0.20 ENST00000494258.1
CASP8 and FADD-like apoptosis regulator
chr12_-_21654479 0.19 ENST00000421138.2
ENST00000444129.2
ENST00000539672.1
ENST00000542432.1
ENST00000536964.1
ENST00000536240.1
ENST00000396093.3
ENST00000314748.6
RecQ protein-like (DNA helicase Q1-like)
chrX_+_119737806 0.19 ENST00000371317.5
malignant T cell amplified sequence 1
chr2_+_201242715 0.19 ENST00000421573.1
spermatogenesis associated, serine-rich 2-like
chr2_+_234104079 0.19 ENST00000417661.1
inositol polyphosphate-5-phosphatase, 145kDa
chr15_+_36871983 0.19 ENST00000437989.2
ENST00000569302.1
chromosome 15 open reading frame 41
chr8_-_95487331 0.19 ENST00000336148.5
RAD54 homolog B (S. cerevisiae)
chr12_-_102455846 0.19 ENST00000545679.1
coiled-coil domain containing 53
chr3_+_186743261 0.19 ENST00000423451.1
ENST00000446170.1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr12_+_79258547 0.19 ENST00000457153.2
synaptotagmin I
chr5_+_68513622 0.18 ENST00000512880.1
ENST00000602380.1
mitochondrial ribosomal protein S36
chrX_+_95939638 0.18 ENST00000373061.3
ENST00000373054.4
ENST00000355827.4
diaphanous-related formin 2
chr17_+_43239191 0.18 ENST00000589230.1
hexamethylene bis-acetamide inducible 2
chr18_+_20494078 0.18 ENST00000579124.1
ENST00000577588.1
ENST00000582354.1
ENST00000581819.1
retinoblastoma binding protein 8
chr6_-_26199471 0.17 ENST00000341023.1
histone cluster 1, H2ad
chr3_+_179280668 0.17 ENST00000429709.2
ENST00000450518.2
ENST00000392662.1
ENST00000490364.1
actin-like 6A
chr3_-_143567262 0.17 ENST00000474151.1
ENST00000316549.6
solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
chr12_-_54653313 0.17 ENST00000550411.1
ENST00000439541.2
chromobox homolog 5
chr18_-_59854203 0.17 ENST00000589339.1
ENST00000357637.5
ENST00000585458.1
ENST00000400334.3
ENST00000587134.1
ENST00000585923.1
ENST00000590765.1
ENST00000589720.1
ENST00000588571.1
ENST00000585344.1
phosphatidylinositol glycan anchor biosynthesis, class N
chrX_+_1734051 0.17 ENST00000381229.4
ENST00000381233.3
acetylserotonin O-methyltransferase
chr5_-_43313574 0.17 ENST00000325110.6
ENST00000433297.2
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr22_+_29138013 0.16 ENST00000216027.3
ENST00000398941.2
HscB mitochondrial iron-sulfur cluster co-chaperone
chr18_+_44526744 0.16 ENST00000585469.1
katanin p60 subunit A-like 2
chr11_+_34938119 0.16 ENST00000227868.4
ENST00000430469.2
ENST00000533262.1
pyruvate dehydrogenase complex, component X
chr4_-_140005443 0.15 ENST00000510408.1
ENST00000420916.2
ENST00000358635.3
E74-like factor 2 (ets domain transcription factor)
chr1_-_54405773 0.15 ENST00000371376.1
heat shock protein family B (small), member 11
chr3_-_120461378 0.15 ENST00000273375.3
RAB, member of RAS oncogene family-like 3
chr19_+_35417939 0.14 ENST00000601142.1
ENST00000426813.2
zinc finger protein 30
chr15_-_54025300 0.13 ENST00000559418.1
WD repeat domain 72
chr14_-_64971893 0.13 ENST00000555220.1
zinc finger and BTB domain containing 25
chr4_+_69962212 0.13 ENST00000508661.1
UDP glucuronosyltransferase 2 family, polypeptide B7
chr11_+_61717336 0.13 ENST00000378042.3
bestrophin 1
chrX_+_95939711 0.13 ENST00000373049.4
ENST00000324765.8
diaphanous-related formin 2
chr11_+_47279155 0.13 ENST00000444396.1
ENST00000457932.1
ENST00000412937.1
nuclear receptor subfamily 1, group H, member 3
chr16_+_19222479 0.13 ENST00000568433.1
synaptotagmin XVII
chr5_-_179045199 0.13 ENST00000523921.1
heterogeneous nuclear ribonucleoprotein H1 (H)
chr14_+_104182105 0.13 ENST00000311141.2
zinc finger, FYVE domain containing 21
chr14_+_104182061 0.13 ENST00000216602.6
zinc finger, FYVE domain containing 21
chr3_-_129158676 0.13 ENST00000393278.2
methyl-CpG binding domain protein 4
chr12_-_15104040 0.12 ENST00000541644.1
ENST00000545895.1
Rho GDP dissociation inhibitor (GDI) beta
chr11_+_61717279 0.12 ENST00000378043.4
bestrophin 1
chr7_-_27142290 0.12 ENST00000222718.5
homeobox A2
chr16_-_49890016 0.12 ENST00000563137.2
zinc finger protein 423
chr3_-_129158850 0.12 ENST00000503197.1
ENST00000249910.1
ENST00000429544.2
ENST00000507208.1
methyl-CpG binding domain protein 4
chr2_+_201997676 0.12 ENST00000462763.1
ENST00000479953.2
CASP8 and FADD-like apoptosis regulator
chr6_+_83777374 0.12 ENST00000349129.2
ENST00000237163.5
ENST00000536812.1
dopey family member 1
chr4_-_48683188 0.12 ENST00000505759.1
FRY-like
chr11_+_114166536 0.12 ENST00000299964.3
nicotinamide N-methyltransferase
chr11_+_122753391 0.12 ENST00000307257.6
ENST00000227349.2
chromosome 11 open reading frame 63
chr13_+_98086445 0.11 ENST00000245304.4
RAP2A, member of RAS oncogene family
chr14_+_50065459 0.11 ENST00000318317.4
leucine rich repeat protein 1
chr5_+_177433406 0.11 ENST00000504530.1
family with sequence similarity 153, member C
chr7_-_38969150 0.11 ENST00000418457.2
vacuolar protein sorting 41 homolog (S. cerevisiae)
chr7_-_112430647 0.11 ENST00000312814.6
transmembrane protein 168
chr5_+_151151504 0.11 ENST00000356245.3
ENST00000507878.2
GTPase activating protein (SH3 domain) binding protein 1
chr10_+_60028818 0.11 ENST00000333926.5
CDGSH iron sulfur domain 1
chr14_-_55907334 0.11 ENST00000247219.5
TATA box binding protein like 2
chr8_+_99076509 0.11 ENST00000318528.3
chromosome 8 open reading frame 47
chr12_+_81471816 0.11 ENST00000261206.3
acyl-CoA synthetase short-chain family member 3
chr2_+_12857043 0.10 ENST00000381465.2
tribbles pseudokinase 2
chr2_-_158182105 0.10 ENST00000409925.1
ermin, ERM-like protein
chr19_-_3801789 0.10 ENST00000590849.1
ENST00000395045.2
megakaryocyte-associated tyrosine kinase
chr7_+_134331550 0.10 ENST00000344924.3
ENST00000418040.1
ENST00000393132.2
2,3-bisphosphoglycerate mutase
chr12_-_57472522 0.10 ENST00000379391.3
ENST00000300128.4
transmembrane protein 194A
chr4_-_69536346 0.10 ENST00000338206.5
UDP glucuronosyltransferase 2 family, polypeptide B15
chr19_+_5681153 0.10 ENST00000579559.1
ENST00000577222.1
hydroxysteroid (11-beta) dehydrogenase 1-like
ribosomal protein L36
chr7_+_77325738 0.10 ENST00000334955.8
round spermatid basic protein 1-like
chr14_+_24584372 0.10 ENST00000559396.1
ENST00000558638.1
ENST00000561041.1
ENST00000559288.1
ENST00000558408.1
DDB1 and CUL4 associated factor 11
chr18_-_48346415 0.10 ENST00000431965.2
ENST00000436348.2
maestro
chr8_-_101965559 0.10 ENST00000353245.3
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr21_-_16125773 0.10 ENST00000454128.2
AF127936.3
chr3_-_161090660 0.10 ENST00000359175.4
serine palmitoyltransferase, small subunit B
chr5_+_151151471 0.10 ENST00000394123.3
ENST00000543466.1
GTPase activating protein (SH3 domain) binding protein 1
chr2_+_20646824 0.10 ENST00000272233.4
ras homolog family member B
chr12_-_56848426 0.10 ENST00000257979.4
major intrinsic protein of lens fiber
chr10_+_69865866 0.10 ENST00000354393.2
myopalladin
chr9_+_113431029 0.10 ENST00000189978.5
ENST00000374448.4
ENST00000374440.3
muscle, skeletal, receptor tyrosine kinase
chr4_-_111536534 0.10 ENST00000503456.1
ENST00000513690.1
RP11-380D23.2
chr17_-_26695013 0.10 ENST00000555059.2
Homeobox protein SEBOX
chr1_+_104293028 0.09 ENST00000370079.3
amylase, alpha 1C (salivary)
chr8_-_101965146 0.09 ENST00000395957.2
ENST00000395948.2
ENST00000457309.1
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr5_-_42825983 0.09 ENST00000506577.1
selenoprotein P, plasma, 1
chr6_-_26199499 0.09 ENST00000377831.5
histone cluster 1, H3d
chr12_-_102455902 0.09 ENST00000240079.6
coiled-coil domain containing 53
chr21_+_27543175 0.08 ENST00000608591.1
ENST00000609365.1
AP000230.1
chr4_+_118349545 0.08 ENST00000422145.3
ENST00000437514.1
AC092661.1
chr12_+_56401268 0.08 ENST00000262032.5
IKAROS family zinc finger 4 (Eos)
chr3_-_72150076 0.08 ENST00000488545.1
ENST00000608654.1
long intergenic non-protein coding RNA 877
chr6_-_84417633 0.08 ENST00000521931.1
synaptosomal-associated protein, 91kDa
chr11_+_68228186 0.08 ENST00000393799.2
ENST00000393800.2
ENST00000528635.1
ENST00000533127.1
ENST00000529907.1
ENST00000529344.1
ENST00000534534.1
ENST00000524845.1
ENST00000265637.4
ENST00000524904.1
ENST00000393801.3
ENST00000265636.5
ENST00000529710.1
protein phosphatase 6, regulatory subunit 3
chr3_+_111451321 0.08 ENST00000393923.3
pleckstrin homology-like domain, family B, member 2
chr6_-_32784687 0.08 ENST00000447394.1
ENST00000438763.2
major histocompatibility complex, class II, DO beta
chr12_+_133657461 0.08 ENST00000412146.2
ENST00000544426.1
ENST00000440984.2
ENST00000319849.3
ENST00000440550.2
zinc finger protein 140
chr15_+_81591757 0.07 ENST00000558332.1
interleukin 16
chr2_+_264913 0.07 ENST00000439645.2
ENST00000405233.1
acid phosphatase 1, soluble
chr3_-_120461353 0.07 ENST00000483733.1
RAB, member of RAS oncogene family-like 3
chr12_-_96389702 0.07 ENST00000552509.1
histidine ammonia-lyase
chr10_-_105845674 0.07 ENST00000353479.5
ENST00000369733.3
collagen, type XVII, alpha 1
chr8_+_133909919 0.07 ENST00000518505.1
thyroglobulin
chr8_-_95487272 0.07 ENST00000297592.5
RAD54 homolog B (S. cerevisiae)
chr2_+_234600253 0.07 ENST00000373424.1
ENST00000441351.1
UDP glucuronosyltransferase 1 family, polypeptide A6
chr6_-_167040693 0.06 ENST00000366863.2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr14_-_69619823 0.06 ENST00000341516.5
DDB1 and CUL4 associated factor 5
chr2_-_154335300 0.06 ENST00000325926.3
reprimo, TP53 dependent G2 arrest mediator candidate
chr20_+_48909240 0.06 ENST00000371639.3
RP11-290F20.1
chrX_+_140084756 0.06 ENST00000449283.1
SPANX family, member B2
chr8_-_116681221 0.06 ENST00000395715.3
trichorhinophalangeal syndrome I
chr22_+_31795509 0.06 ENST00000331457.4
developmentally regulated GTP binding protein 1
chr2_-_27886676 0.06 ENST00000337768.5
suppressor of Ty 7 (S. cerevisiae)-like
chr2_+_44396000 0.06 ENST00000409895.4
ENST00000409432.3
ENST00000282412.4
ENST00000378551.2
ENST00000345249.4
protein phosphatase, Mg2+/Mn2+ dependent, 1B
chr21_+_27011899 0.06 ENST00000425221.2
junctional adhesion molecule 2
chr16_+_50059125 0.06 ENST00000427478.2
CTD nuclear envelope phosphatase 1 regulatory subunit 1
chr7_-_107883678 0.06 ENST00000417701.1
neuronal cell adhesion molecule
chr1_-_115323245 0.05 ENST00000060969.5
ENST00000369528.5
suppressor of IKBKE 1
chr12_+_123944070 0.05 ENST00000412157.2
small nuclear ribonucleoprotein 35kDa (U11/U12)
chr4_-_38784592 0.05 ENST00000502321.1
toll-like receptor 10
chr15_-_60695071 0.05 ENST00000557904.1
annexin A2
chr13_-_24895566 0.05 ENST00000422229.2
protein PCOTH isoform 1
chr6_-_84418432 0.05 ENST00000519825.1
ENST00000523484.2
synaptosomal-associated protein, 91kDa

Network of associatons between targets according to the STRING database.

First level regulatory network of PBX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0045081 negative regulation of interleukin-10 biosynthetic process(GO:0045081)
0.1 0.5 GO:0006781 succinyl-CoA pathway(GO:0006781)
0.1 0.4 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.1 1.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.5 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1 0.2 GO:1903925 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.3 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.1 0.2 GO:0002188 translation reinitiation(GO:0002188)
0.1 0.2 GO:0007231 osmosensory signaling pathway(GO:0007231)
0.1 0.2 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1 0.3 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.1 0.3 GO:0044245 polysaccharide digestion(GO:0044245)
0.1 0.5 GO:0070269 pyroptosis(GO:0070269)
0.1 0.6 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.4 GO:1905068 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.7 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.2 GO:0071684 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.6 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.3 GO:0019236 response to pheromone(GO:0019236)
0.0 0.1 GO:0035284 rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.4 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.2 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.0 0.3 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.3 GO:0002740 negative regulation of cytokine secretion involved in immune response(GO:0002740) Tie signaling pathway(GO:0048014)
0.0 0.7 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.2 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 0.1 GO:0032053 ciliary basal body organization(GO:0032053)
0.0 0.1 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.1 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586)
0.0 0.2 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 0.3 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.4 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.2 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.2 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.3 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.8 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.5 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.3 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.4 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 0.1 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.3 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.3 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.2 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 1.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.2 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.1 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.0 0.0 GO:0071400 carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) cellular response to oleic acid(GO:0071400) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718)
0.0 0.2 GO:0045008 depyrimidination(GO:0045008)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.0 0.2 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.2 GO:0009812 flavonoid metabolic process(GO:0009812)
0.0 0.8 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.0 GO:0060981 cell migration involved in coronary angiogenesis(GO:0060981)
0.0 0.1 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.0 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.0 0.9 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.0 GO:0071140 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0070985 TFIIK complex(GO:0070985)
0.1 0.3 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1 0.5 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 0.4 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.1 0.5 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 0.7 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 0.2 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.4 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.6 GO:0097342 ripoptosome(GO:0097342)
0.0 0.4 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.1 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 0.2 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.3 GO:0000796 condensin complex(GO:0000796)
0.0 0.2 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.0 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.0 0.2 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.1 GO:0033269 internode region of axon(GO:0033269)
0.0 0.1 GO:0033263 CORVET complex(GO:0033263)
0.0 1.1 GO:0070469 respiratory chain(GO:0070469)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.1 0.5 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.1 1.0 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.7 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 0.2 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.1 0.3 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 0.3 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.2 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1 0.7 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 0.3 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.2 GO:0008263 pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
0.0 0.5 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.2 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.0 0.4 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.1 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.3 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
0.0 0.3 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.1 GO:0030760 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.0 0.1 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0 0.1 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.2 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.2 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.2 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.1 GO:0004397 histidine ammonia-lyase activity(GO:0004397)
0.0 0.6 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.0 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.2 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.4 GO:0000150 recombinase activity(GO:0000150)
0.0 0.2 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 1.2 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.4 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.2 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.6 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.6 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0032810 sterol response element binding(GO:0032810)
0.0 0.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.0 GO:0004772 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.0 0.3 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.4 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.0 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.0 0.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.4 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.6 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.4 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.6 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.5 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.2 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.3 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.2 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.3 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines