Project
A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)
Navigation
Downloads
Results for PAX7_NOBOX
Z-value: 1.27
Motif logo
Transcription factors associated with PAX7_NOBOX
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| PAX7 | hg19_v2_chr1_+_18958008_18958023 | 0.26 | 6.2e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr6_+_3259148 Show fit | 1.72 |
ENST00000419065.2
ENST00000473000.2 ENST00000451246.2 ENST00000454610.2 |
proteasome (prosome, macropain) assembly chaperone 4 |
|
| chr13_+_110958124 Show fit | 1.71 |
ENST00000400163.2
|
collagen, type IV, alpha 2 |
|
| chr6_-_170151603 Show fit | 1.43 |
ENST00000366774.3
|
t-complex-associated-testis-expressed 3 |
|
| chr22_-_32766972 Show fit | 1.15 |
ENST00000382084.4
ENST00000382086.2 |
RFPL3 antisense |
|
| chr5_+_35852797 Show fit | 0.99 |
ENST00000508941.1
|
interleukin 7 receptor |
|
| chr1_+_162336686 Show fit | 0.98 |
ENST00000420220.1
|
chromosome 1 open reading frame 226 |
|
| chr17_+_19091325 Show fit | 0.92 |
ENST00000584923.1
|
small nucleolar RNA, C/D box 3A |
|
| chr2_-_152118276 Show fit | 0.81 |
ENST00000409092.1
|
RNA binding motif protein 43 |
|
| chr19_-_3557570 Show fit | 0.79 |
ENST00000355415.2
|
major facilitator superfamily domain containing 12 |
|
| chr1_+_1260598 Show fit | 0.74 |
ENST00000488011.1
|
glycolipid transfer protein domain containing 1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of PAX7_NOBOX
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.5 | GO:0043248 | proteasome assembly(GO:0043248) |
| 0.1 | 1.7 | GO:0072643 | interferon-gamma secretion(GO:0072643) |
| 0.1 | 1.7 | GO:0038063 | collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) |
| 0.1 | 1.0 | GO:0001915 | negative regulation of T cell mediated cytotoxicity(GO:0001915) |
| 0.1 | 0.9 | GO:0090063 | positive regulation of microtubule nucleation(GO:0090063) |
| 0.2 | 0.8 | GO:0019747 | regulation of isoprenoid metabolic process(GO:0019747) |
| 0.0 | 0.8 | GO:0018345 | protein palmitoylation(GO:0018345) |
| 0.1 | 0.7 | GO:0002227 | innate immune response in mucosa(GO:0002227) |
| 0.1 | 0.7 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 0.0 | 0.7 | GO:0071539 | protein localization to centrosome(GO:0071539) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 1.7 | GO:0005587 | collagen type IV trimer(GO:0005587) |
| 0.0 | 1.7 | GO:0030286 | dynein complex(GO:0030286) |
| 0.2 | 0.7 | GO:0044301 | climbing fiber(GO:0044301) |
| 0.0 | 0.7 | GO:0005869 | dynactin complex(GO:0005869) |
| 0.0 | 0.7 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.0 | 0.7 | GO:0000786 | nucleosome(GO:0000786) |
| 0.0 | 0.6 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
| 0.0 | 0.6 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.0 | 0.6 | GO:0090665 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
| 0.2 | 0.5 | GO:1990597 | AIP1-IRE1 complex(GO:1990597) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.6 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.0 | 1.2 | GO:0030971 | receptor tyrosine kinase binding(GO:0030971) |
| 0.2 | 1.0 | GO:0004917 | interleukin-7 receptor activity(GO:0004917) |
| 0.0 | 0.8 | GO:0019706 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
| 0.0 | 0.8 | GO:0015485 | cholesterol binding(GO:0015485) |
| 0.0 | 0.7 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.0 | 0.7 | GO:0070840 | dynein complex binding(GO:0070840) |
| 0.0 | 0.7 | GO:0051539 | 4 iron, 4 sulfur cluster binding(GO:0051539) |
| 0.1 | 0.6 | GO:0004982 | N-formyl peptide receptor activity(GO:0004982) |
| 0.1 | 0.6 | GO:0044729 | hemi-methylated DNA-binding(GO:0044729) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.8 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.0 | 1.1 | PID CD40 PATHWAY | CD40/CD40L signaling |
| 0.0 | 1.0 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.0 | 0.8 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.0 | 0.6 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.0 | 0.4 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
| 0.0 | 0.3 | PID S1P S1P4 PATHWAY | S1P4 pathway |
| 0.0 | 0.2 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 0.0 | 0.2 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.7 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.0 | 1.0 | REACTOME IL 7 SIGNALING | Genes involved in Interleukin-7 signaling |
| 0.0 | 1.0 | REACTOME PACKAGING OF TELOMERE ENDS | Genes involved in Packaging Of Telomere Ends |
| 0.0 | 0.7 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
| 0.0 | 0.7 | REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
| 0.0 | 0.5 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
| 0.0 | 0.5 | REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS | Genes involved in Homologous recombination repair of replication-independent double-strand breaks |
| 0.0 | 0.5 | REACTOME PYRIMIDINE METABOLISM | Genes involved in Pyrimidine metabolism |
| 0.0 | 0.4 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.0 | 0.4 | REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |