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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for PAX4
Z-value: 0.99
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Transcription factors associated with PAX4
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr12_-_121476959 Show fit | 0.73 |
ENST00000339275.5
|
2'-5'-oligoadenylate synthetase-like |
|
| chr12_-_121477039 Show fit | 0.68 |
ENST00000257570.5
|
2'-5'-oligoadenylate synthetase-like |
|
| chr6_-_10694766 Show fit | 0.47 |
ENST00000460742.2
ENST00000259983.3 ENST00000379586.1 |
chromosome 6 open reading frame 52 |
|
| chr12_-_123717711 Show fit | 0.47 |
ENST00000537854.1
|
M-phase phosphoprotein 9 |
|
| chr6_-_32083106 Show fit | 0.43 |
ENST00000442721.1
|
tenascin XB |
|
| chr2_-_191878162 Show fit | 0.39 |
ENST00000540176.1
|
signal transducer and activator of transcription 1, 91kDa |
|
| chr5_+_146614579 Show fit | 0.38 |
ENST00000541094.1
ENST00000398521.3 |
serine/threonine kinase 32A |
|
| chr7_-_139763521 Show fit | 0.37 |
ENST00000263549.3
|
poly (ADP-ribose) polymerase family, member 12 |
|
| chr10_-_69991865 Show fit | 0.33 |
ENST00000373673.3
|
atonal homolog 7 (Drosophila) |
|
| chr11_-_96239990 Show fit | 0.32 |
ENST00000511243.2
|
JRKL antisense RNA 1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of PAX4
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.4 | GO:0045071 | negative regulation of viral genome replication(GO:0045071) |
| 0.0 | 0.6 | GO:1903861 | positive regulation of dendrite extension(GO:1903861) |
| 0.0 | 0.5 | GO:0071539 | protein localization to centrosome(GO:0071539) |
| 0.1 | 0.4 | GO:0046725 | negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) |
| 0.0 | 0.4 | GO:0048251 | elastic fiber assembly(GO:0048251) |
| 0.0 | 0.4 | GO:2000096 | positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096) |
| 0.0 | 0.3 | GO:0021554 | optic nerve development(GO:0021554) |
| 0.1 | 0.2 | GO:1903939 | negative regulation of histone H3-K9 dimethylation(GO:1900110) regulation of TORC2 signaling(GO:1903939) |
| 0.0 | 0.2 | GO:0006269 | DNA replication, synthesis of RNA primer(GO:0006269) |
| 0.0 | 0.2 | GO:0071279 | cellular response to cobalt ion(GO:0071279) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.5 | GO:0031313 | extrinsic component of endosome membrane(GO:0031313) |
| 0.0 | 0.4 | GO:0005583 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
| 0.0 | 0.3 | GO:0097255 | R2TP complex(GO:0097255) |
| 0.0 | 0.2 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
| 0.0 | 0.2 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
| 0.0 | 0.2 | GO:0005672 | transcription factor TFIIA complex(GO:0005672) |
| 0.0 | 0.2 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
| 0.0 | 0.2 | GO:0016461 | unconventional myosin complex(GO:0016461) |
| 0.0 | 0.1 | GO:0032449 | CBM complex(GO:0032449) |
| 0.0 | 0.1 | GO:0032302 | MutSbeta complex(GO:0032302) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.4 | GO:0001730 | 2'-5'-oligoadenylate synthetase activity(GO:0001730) |
| 0.0 | 0.6 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
| 0.0 | 0.2 | GO:0003896 | DNA primase activity(GO:0003896) |
| 0.0 | 0.2 | GO:0001165 | RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165) |
| 0.0 | 0.1 | GO:0004139 | deoxyribose-phosphate aldolase activity(GO:0004139) |
| 0.0 | 0.1 | GO:0004464 | leukotriene-C4 synthase activity(GO:0004464) |
| 0.0 | 0.1 | GO:0005019 | platelet-derived growth factor beta-receptor activity(GO:0005019) |
| 0.0 | 0.1 | GO:0000406 | double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181) |
| 0.0 | 0.1 | GO:0003875 | ADP-ribosylarginine hydrolase activity(GO:0003875) |
| 0.0 | 0.1 | GO:0030760 | nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.4 | ST INTERFERON GAMMA PATHWAY | Interferon gamma pathway. |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.4 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.0 | 0.4 | REACTOME IL 6 SIGNALING | Genes involved in Interleukin-6 signaling |