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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for OLIG2_NEUROD1_ATOH1

Z-value: 1.18

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Transcription factors associated with OLIG2_NEUROD1_ATOH1

Gene Symbol Gene ID Gene Info
ENSG00000205927.4 oligodendrocyte transcription factor 2
ENSG00000162992.3 neuronal differentiation 1
ENSG00000172238.3 atonal bHLH transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NEUROD1hg19_v2_chr2_-_182545603_182545603-0.824.4e-02Click!
OLIG2hg19_v2_chr21_+_34398153_34398250-0.315.5e-01Click!

Activity profile of OLIG2_NEUROD1_ATOH1 motif

Sorted Z-values of OLIG2_NEUROD1_ATOH1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_58145889 2.14 ENST00000547853.1
cyclin-dependent kinase 4
chr8_-_135522425 2.02 ENST00000521673.1
zinc finger and AT hook domain containing
chr3_-_52486841 1.21 ENST00000496590.1
troponin C type 1 (slow)
chr5_-_159766528 1.20 ENST00000505287.2
cyclin J-like
chr12_-_13105081 1.18 ENST00000541128.1
G protein-coupled receptor, family C, group 5, member D
chr19_+_41222998 0.96 ENST00000263370.2
inositol-trisphosphate 3-kinase C
chr16_+_83932684 0.92 ENST00000262430.4
malonyl-CoA decarboxylase
chr3_-_52869205 0.92 ENST00000446157.2
musculoskeletal, embryonic nuclear protein 1
chr5_-_180632147 0.88 ENST00000274773.7
tripartite motif containing 7
chr17_+_45286706 0.86 ENST00000393450.1
ENST00000572303.1
myosin, light chain 4, alkali; atrial, embryonic
chr2_-_132589601 0.82 ENST00000437330.1
AC103564.7
chr14_-_75079294 0.80 ENST00000556359.1
latent transforming growth factor beta binding protein 2
chr10_-_105437909 0.73 ENST00000540321.1
SH3 and PX domains 2A
chr3_-_178789220 0.72 ENST00000414084.1
zinc finger, matrin-type 3
chr16_-_21289627 0.71 ENST00000396023.2
ENST00000415987.2
crystallin, mu
chr16_+_57438679 0.71 ENST00000219244.4
chemokine (C-C motif) ligand 17
chr1_+_19967014 0.70 ENST00000428975.1
neuroblastoma 1, DAN family BMP antagonist
chr6_-_26250835 0.69 ENST00000446824.2
histone cluster 1, H3f
chr1_+_12524965 0.68 ENST00000471923.1
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr1_+_180897269 0.65 ENST00000367587.1
KIAA1614
chr4_-_24914576 0.64 ENST00000502801.1
ENST00000428116.2
coiled-coil domain containing 149
chr19_+_36249044 0.63 ENST00000444637.2
ENST00000396908.4
ENST00000544099.1
chromosome 19 open reading frame 55
chr4_-_24914508 0.62 ENST00000504487.1
coiled-coil domain containing 149
chr19_+_19030497 0.61 ENST00000438170.2
DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
chr19_-_4338783 0.60 ENST00000601482.1
ENST00000600324.1
signal transducing adaptor family member 2
chr11_+_20044096 0.58 ENST00000533917.1
neuron navigator 2
chr8_-_133772870 0.57 ENST00000522334.1
ENST00000519016.1
transmembrane protein 71
chr1_+_110881945 0.57 ENST00000602849.1
ENST00000487146.2
RNA binding motif protein 15
chr19_+_19030478 0.57 ENST00000247003.4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
chr5_+_71475449 0.56 ENST00000504492.1
microtubule-associated protein 1B
chr20_-_52645231 0.56 ENST00000448484.1
breast carcinoma amplified sequence 1
chr1_+_226736446 0.56 ENST00000366788.3
ENST00000366789.4
chromosome 1 open reading frame 95
chr7_-_150777920 0.54 ENST00000353841.2
ENST00000297532.6
Fas-activated serine/threonine kinase
chrX_+_118108571 0.54 ENST00000304778.7
LON peptidase N-terminal domain and ring finger 3
chr11_-_72070206 0.53 ENST00000544382.1
ClpB caseinolytic peptidase B homolog (E. coli)
chr1_-_206945830 0.52 ENST00000423557.1
interleukin 10
chr2_+_74229812 0.52 ENST00000305799.7
tet methylcytosine dioxygenase 3
chrX_-_102565932 0.51 ENST00000372674.1
ENST00000372677.3
brain expressed X-linked 2
chr19_-_40772221 0.51 ENST00000441941.2
ENST00000580747.1
v-akt murine thymoma viral oncogene homolog 2
chr7_-_150777949 0.50 ENST00000482571.1
Fas-activated serine/threonine kinase
chr17_-_47286729 0.50 ENST00000300406.2
ENST00000511277.1
ENST00000511673.1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr12_+_79371565 0.50 ENST00000551304.1
synaptotagmin I
chr11_+_827553 0.49 ENST00000528542.2
ENST00000450448.1
EF-hand calcium binding domain 4A
chr8_-_41522779 0.49 ENST00000522231.1
ENST00000314214.8
ENST00000348036.4
ENST00000457297.1
ENST00000522543.1
ankyrin 1, erythrocytic
chr4_+_53525573 0.48 ENST00000503051.1
USP46 antisense RNA 1
chr18_-_56985776 0.48 ENST00000587244.1
complexin 4
chr1_+_12538594 0.48 ENST00000543710.1
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr12_+_107712173 0.48 ENST00000280758.5
ENST00000420571.2
BTB (POZ) domain containing 11
chr18_+_59415396 0.47 ENST00000567801.1
RP11-1096D5.1
chr19_-_19030157 0.46 ENST00000349893.4
ENST00000351079.4
ENST00000600932.1
ENST00000262812.4
coatomer protein complex, subunit epsilon
chr5_+_72509751 0.45 ENST00000515556.1
ENST00000513379.1
ENST00000427584.2
RP11-60A8.1
chr7_-_74867509 0.45 ENST00000426327.3
GATS protein-like 2
chr12_+_122150646 0.44 ENST00000449592.2
transmembrane protein 120B
chr19_-_1650666 0.44 ENST00000588136.1
transcription factor 3
chr6_+_155443048 0.44 ENST00000535583.1
T-cell lymphoma invasion and metastasis 2
chr22_-_37882395 0.43 ENST00000416983.3
ENST00000424765.2
ENST00000356998.3
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr5_+_139055055 0.43 ENST00000511457.1
CXXC finger protein 5
chr11_-_57417405 0.42 ENST00000524669.1
ENST00000300022.3
yippee-like 4 (Drosophila)
chr16_+_72142195 0.42 ENST00000563819.1
ENST00000567142.2
DEAH (Asp-Glu-Ala-His) box polypeptide 38
chr4_+_113970772 0.41 ENST00000504454.1
ENST00000394537.3
ENST00000357077.4
ENST00000264366.6
ankyrin 2, neuronal
chr7_+_143078652 0.41 ENST00000354434.4
ENST00000449423.2
zyxin
chr7_-_97881429 0.39 ENST00000420697.1
ENST00000379795.3
ENST00000415086.1
ENST00000542604.1
ENST00000447648.2
tectonin beta-propeller repeat containing 1
chr1_+_17559776 0.38 ENST00000537499.1
ENST00000413717.2
ENST00000536552.1
peptidyl arginine deiminase, type I
chrX_+_118108601 0.38 ENST00000371628.3
LON peptidase N-terminal domain and ring finger 3
chr7_+_143079000 0.37 ENST00000392910.2
zyxin
chr18_-_25739260 0.37 ENST00000413878.1
cadherin 2, type 1, N-cadherin (neuronal)
chr2_-_220117867 0.37 ENST00000456818.1
ENST00000447205.1
tubulin, alpha 4a
chr17_-_7216939 0.37 ENST00000573684.1
G protein pathway suppressor 2
chr19_-_44008863 0.36 ENST00000601646.1
pleckstrin homology-like domain, family B, member 3
chr4_+_114214125 0.36 ENST00000509550.1
ankyrin 2, neuronal
chr9_+_19408919 0.35 ENST00000380376.1
alkaline ceramidase 2
chr15_+_75940218 0.35 ENST00000308527.5
sorting nexin 33
chr10_-_15413035 0.35 ENST00000378116.4
ENST00000455654.1
family with sequence similarity 171, member A1
chr12_-_68845417 0.34 ENST00000542875.1
RP11-81H14.2
chr16_-_25026641 0.34 ENST00000289968.6
ENST00000303665.5
ENST00000455311.2
ENST00000441763.2
Rho GTPase activating protein 17
chr12_-_57634475 0.34 ENST00000393825.1
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr1_-_219615984 0.33 ENST00000420762.1
RP11-95P13.1
chr17_-_76713100 0.33 ENST00000585509.1
cytohesin 1
chr22_-_21905120 0.33 ENST00000331505.5
RIMS binding protein 3C
chr9_+_116298778 0.33 ENST00000462143.1
regulator of G-protein signaling 3
chr12_-_49319265 0.32 ENST00000552878.1
ENST00000453172.2
FK506 binding protein 11, 19 kDa
chr5_+_139055021 0.32 ENST00000502716.1
ENST00000503511.1
CXXC finger protein 5
chr15_-_40633101 0.32 ENST00000559313.1
chromosome 15 open reading frame 52
chr11_-_63933504 0.31 ENST00000255681.6
MACRO domain containing 1
chr9_+_131644388 0.31 ENST00000372600.4
leucine rich repeat containing 8 family, member A
chr14_+_93389425 0.31 ENST00000216492.5
ENST00000334654.4
chromogranin A (parathyroid secretory protein 1)
chr2_-_225811747 0.30 ENST00000409592.3
dedicator of cytokinesis 10
chr16_-_79633799 0.30 ENST00000569649.1
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
chr1_-_209792111 0.30 ENST00000455193.1
laminin, beta 3
chr7_+_5229819 0.30 ENST00000288828.4
ENST00000401525.3
ENST00000404704.3
WD repeat domain, phosphoinositide interacting 2
chr17_-_67057047 0.30 ENST00000495634.1
ENST00000453985.2
ENST00000585714.1
ATP-binding cassette, sub-family A (ABC1), member 9
chr9_+_2029019 0.30 ENST00000382194.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr11_+_44587141 0.30 ENST00000227155.4
ENST00000342935.3
ENST00000532544.1
CD82 molecule
chr17_-_39623681 0.29 ENST00000225899.3
keratin 32
chr11_-_1587166 0.29 ENST00000331588.4
dual specificity phosphatase 8
chr19_-_39368887 0.29 ENST00000340740.3
ENST00000591812.1
Ras and Rab interactor-like
chr9_+_135037334 0.29 ENST00000393229.3
ENST00000360670.3
ENST00000393228.4
ENST00000372179.3
netrin G2
chr1_-_154941350 0.28 ENST00000444179.1
ENST00000414115.1
SHC (Src homology 2 domain containing) transforming protein 1
chr15_-_75660919 0.28 ENST00000569482.1
ENST00000565683.1
ENST00000561615.1
ENST00000563622.1
ENST00000568374.1
ENST00000566256.1
ENST00000267978.5
mannosidase, alpha, class 2C, member 1
chr19_-_4454081 0.28 ENST00000591919.1
UBX domain protein 6
chr12_-_58145604 0.28 ENST00000552254.1
cyclin-dependent kinase 4
chr5_-_99870932 0.28 ENST00000504833.1
CTD-2001C12.1
chr16_+_67280799 0.28 ENST00000566345.2
solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
chr1_-_149812765 0.28 ENST00000369158.1
histone cluster 2, H3c
chr2_+_7005959 0.27 ENST00000442639.1
radical S-adenosyl methionine domain containing 2
chr9_+_131644398 0.27 ENST00000372599.3
leucine rich repeat containing 8 family, member A
chr15_-_42749711 0.27 ENST00000565611.1
ENST00000263805.4
ENST00000565948.1
zinc finger protein 106
chr19_-_56056888 0.27 ENST00000592464.1
ENST00000420723.3
SH3 domain binding kinase family, member 3
chr20_-_56284816 0.27 ENST00000395819.3
ENST00000341744.3
prostate transmembrane protein, androgen induced 1
chr11_+_76494253 0.27 ENST00000333090.4
tsukushi, small leucine rich proteoglycan
chr9_-_140351928 0.27 ENST00000339554.3
NMDA receptor synaptonuclear signaling and neuronal migration factor
chr12_+_116997186 0.26 ENST00000306985.4
microtubule-associated protein 1 light chain 3 beta 2
chr12_-_70093235 0.26 ENST00000266661.4
bestrophin 3
chr7_-_44105158 0.26 ENST00000297283.3
phosphoglycerate mutase 2 (muscle)
chr10_-_103347883 0.26 ENST00000339310.3
ENST00000370158.3
ENST00000299206.4
ENST00000456836.2
ENST00000413344.1
ENST00000429502.1
ENST00000430045.1
ENST00000370172.1
ENST00000436284.2
ENST00000370162.3
polymerase (DNA directed), lambda
chrX_-_153583257 0.26 ENST00000438732.1
filamin A, alpha
chr10_+_102759545 0.26 ENST00000454422.1
leucine zipper, putative tumor suppressor 2
chr19_-_6057282 0.26 ENST00000592281.1
regulatory factor X, 2 (influences HLA class II expression)
chr4_+_169633310 0.25 ENST00000510998.1
palladin, cytoskeletal associated protein
chr9_+_131174024 0.25 ENST00000420034.1
ENST00000372842.1
cerebral endothelial cell adhesion molecule
chr12_+_6833323 0.25 ENST00000544725.1
COP9 signalosome subunit 7A
chrX_-_63005405 0.25 ENST00000374878.1
ENST00000437457.2
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr11_+_117073850 0.25 ENST00000529622.1
transgelin
chr9_+_131644781 0.25 ENST00000259324.5
leucine rich repeat containing 8 family, member A
chr14_-_75078725 0.25 ENST00000556690.1
latent transforming growth factor beta binding protein 2
chr5_+_156887027 0.25 ENST00000435489.2
ENST00000311946.7
NIPA-like domain containing 4
chr1_+_236557569 0.25 ENST00000334232.4
EDAR-associated death domain
chr7_+_75931861 0.25 ENST00000248553.6
heat shock 27kDa protein 1
chr8_-_37594944 0.25 ENST00000330539.1
Uncharacterized protein
chr1_+_1567474 0.25 ENST00000356026.5
matrix metallopeptidase 23B
chr7_+_5229904 0.25 ENST00000382384.2
WD repeat domain, phosphoinositide interacting 2
chr19_+_45204630 0.24 ENST00000405314.2
carcinoembryonic antigen-related cell adhesion molecule 16
chr3_-_65583561 0.24 ENST00000460329.2
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr22_-_42342692 0.24 ENST00000404067.1
ENST00000402338.1
centromere protein M
chr12_+_57916466 0.24 ENST00000355673.3
methyl-CpG binding domain protein 6
chr12_+_49212514 0.24 ENST00000301050.2
ENST00000548279.1
ENST00000547230.1
calcium channel, voltage-dependent, beta 3 subunit
chr15_+_67547113 0.24 ENST00000512104.1
ENST00000358767.3
ENST00000546225.1
IQ motif containing H
chr1_-_243326612 0.24 ENST00000492145.1
ENST00000490813.1
ENST00000464936.1
centrosomal protein 170kDa
chr16_+_71660052 0.24 ENST00000567566.1
MARVEL domain containing 3
chr3_-_50383096 0.24 ENST00000442887.1
ENST00000360165.3
zinc finger, MYND-type containing 10
chrX_-_73512177 0.24 ENST00000603672.1
ENST00000418855.1
FTX transcript, XIST regulator (non-protein coding)
chr3_-_87040259 0.24 ENST00000383698.3
vestigial like 3 (Drosophila)
chr17_-_56492989 0.23 ENST00000583753.1
ring finger protein 43
chr3_+_35722424 0.23 ENST00000396481.2
cAMP-regulated phosphoprotein, 21kDa
chr17_+_7477040 0.23 ENST00000581384.1
ENST00000577929.1
eukaryotic translation initiation factor 4A1
chr10_-_99531709 0.23 ENST00000266066.3
secreted frizzled-related protein 5
chr19_-_46285736 0.23 ENST00000291270.4
ENST00000447742.2
ENST00000354227.5
dystrophia myotonica-protein kinase
chr11_+_45918092 0.23 ENST00000395629.2
mitogen-activated protein kinase 8 interacting protein 1
chr1_-_226111929 0.22 ENST00000343818.6
ENST00000432920.2
pyrroline-5-carboxylate reductase family, member 2
Uncharacterized protein
chr9_+_2017063 0.22 ENST00000457226.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr12_+_4714145 0.22 ENST00000545342.1
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
chr7_-_99869799 0.22 ENST00000436886.2
GATS, stromal antigen 3 opposite strand
chr3_+_118892411 0.22 ENST00000479520.1
ENST00000494855.1
uroplakin 1B
chr17_-_4689727 0.22 ENST00000328739.5
ENST00000354194.4
vitelline membrane outer layer 1 homolog (chicken)
chr16_+_28996416 0.22 ENST00000395456.2
ENST00000454369.2
linker for activation of T cells
chr12_+_32654965 0.22 ENST00000472289.1
FYVE, RhoGEF and PH domain containing 4
chr19_+_18111927 0.22 ENST00000379656.3
arrestin domain containing 2
chr17_-_3500392 0.21 ENST00000571088.1
ENST00000174621.6
transient receptor potential cation channel, subfamily V, member 1
chr12_+_58176525 0.21 ENST00000543727.1
ENST00000540550.1
ENST00000323833.8
ENST00000350762.5
ENST00000550559.1
ENST00000548851.1
ENST00000434359.1
ENST00000457189.1
Ts translation elongation factor, mitochondrial
chr6_+_29555683 0.21 ENST00000383640.2
olfactory receptor, family 2, subfamily H, member 2
chr19_+_17416457 0.21 ENST00000252602.1
mitochondrial ribosomal protein L34
chr6_-_131211534 0.20 ENST00000456097.2
erythrocyte membrane protein band 4.1-like 2
chr16_+_2510081 0.20 ENST00000361837.4
ENST00000569496.1
ENST00000567489.1
ENST00000563531.1
ENST00000483320.1
chromosome 16 open reading frame 59
chr13_+_49794474 0.20 ENST00000218721.1
ENST00000398307.1
motilin receptor
chr17_-_27405875 0.20 ENST00000359450.6
TGFB1-induced anti-apoptotic factor 1
chr6_+_30851840 0.20 ENST00000511510.1
ENST00000376569.3
ENST00000376575.3
ENST00000376570.4
ENST00000446312.1
ENST00000504927.1
discoidin domain receptor tyrosine kinase 1
chr11_+_7597639 0.20 ENST00000533792.1
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr22_-_36236265 0.20 ENST00000414461.2
ENST00000416721.2
ENST00000449924.2
ENST00000262829.7
ENST00000397305.3
RNA binding protein, fox-1 homolog (C. elegans) 2
chr1_+_223101757 0.20 ENST00000284476.6
dispatched homolog 1 (Drosophila)
chr12_+_53846612 0.20 ENST00000551104.1
poly(rC) binding protein 2
chr5_+_59783941 0.19 ENST00000506884.1
ENST00000504876.2
prostate androgen-regulated transcript 1 (non-protein coding)
chr2_-_27603582 0.19 ENST00000323703.6
ENST00000436006.1
zinc finger protein 513
chr18_-_59274139 0.19 ENST00000586949.1
RP11-879F14.2
chrX_+_70521584 0.19 ENST00000373829.3
ENST00000538820.1
integrin beta 1 binding protein (melusin) 2
chr7_-_150777874 0.19 ENST00000540185.1
Fas-activated serine/threonine kinase
chr16_-_30107491 0.19 ENST00000566134.1
ENST00000565110.1
ENST00000398841.1
ENST00000398838.4
yippee-like 3 (Drosophila)
chr7_-_86848933 0.19 ENST00000423734.1
transmembrane protein 243, mitochondrial
chr12_-_48152428 0.19 ENST00000449771.2
ENST00000395358.3
Rap guanine nucleotide exchange factor (GEF) 3
chr3_+_111393659 0.19 ENST00000477665.1
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr2_-_220083076 0.19 ENST00000295750.4
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr1_+_55013889 0.19 ENST00000343744.2
ENST00000371316.3
acyl-CoA thioesterase 11
chr11_-_59633951 0.19 ENST00000257264.3
transcobalamin I (vitamin B12 binding protein, R binder family)
chr9_+_12695702 0.19 ENST00000381136.2
tyrosinase-related protein 1
chr19_-_46285646 0.19 ENST00000458663.2
dystrophia myotonica-protein kinase
chr7_-_11871815 0.19 ENST00000423059.4
thrombospondin, type I, domain containing 7A
chr22_-_31885514 0.18 ENST00000397525.1
eukaryotic translation initiation factor 4E nuclear import factor 1
chr19_+_18794470 0.18 ENST00000321949.8
ENST00000338797.6
CREB regulated transcription coactivator 1
chr19_+_36249057 0.18 ENST00000301165.5
ENST00000536950.1
ENST00000537459.1
ENST00000421853.2
chromosome 19 open reading frame 55
chrX_-_73512411 0.18 ENST00000602576.1
ENST00000429124.1
FTX transcript, XIST regulator (non-protein coding)
chr19_-_19774473 0.18 ENST00000357324.6
ATPase type 13A1
chr12_+_6833437 0.18 ENST00000534947.1
ENST00000541866.1
ENST00000534877.1
ENST00000538753.1
COP9 signalosome subunit 7A
chr18_-_72920372 0.18 ENST00000581620.1
ENST00000582437.1
zinc binding alcohol dehydrogenase domain containing 2
chr7_+_66800928 0.18 ENST00000430244.1
RP11-166O4.5
chr8_+_22411931 0.18 ENST00000523402.1
sorbin and SH3 domain containing 3
chr17_-_77813186 0.18 ENST00000448310.1
ENST00000269397.4
chromobox homolog 4
chr17_-_1012305 0.18 ENST00000291107.2
active BCR-related
chr16_+_57847684 0.18 ENST00000335616.2
uncharacterized protein LOC388282
chr8_-_145018080 0.18 ENST00000354589.3
plectin
chrX_-_30993201 0.17 ENST00000288422.2
ENST00000378932.2
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr2_+_128177458 0.17 ENST00000409048.1
ENST00000422777.3
protein C (inactivator of coagulation factors Va and VIIIa)

Network of associatons between targets according to the STRING database.

First level regulatory network of OLIG2_NEUROD1_ATOH1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.7 GO:1904637 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.3 1.2 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.2 0.9 GO:0036115 fatty-acyl-CoA catabolic process(GO:0036115)
0.2 0.5 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.2 0.5 GO:0044727 DNA demethylation of male pronucleus(GO:0044727)
0.2 0.8 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 0.7 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.1 0.7 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.1 0.3 GO:1900738 dense core granule biogenesis(GO:0061110) positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738) positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of dense core granule biogenesis(GO:2000705)
0.1 0.4 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.1 0.3 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.1 0.5 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1 0.2 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.1 0.4 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.1 0.3 GO:0018277 protein deamination(GO:0018277)
0.1 0.5 GO:0097473 cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.1 0.5 GO:0061739 protein lipidation involved in autophagosome assembly(GO:0061739)
0.1 0.3 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.1 0.3 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.1 2.1 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.1 0.6 GO:0021564 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025) vagus nerve development(GO:0021564)
0.1 0.2 GO:0045083 negative regulation of interleukin-12 biosynthetic process(GO:0045083)
0.1 0.4 GO:0002326 B cell lineage commitment(GO:0002326)
0.1 0.2 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.1 0.7 GO:0002329 pre-B cell differentiation(GO:0002329)
0.1 0.3 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.1 0.2 GO:0021569 rhombomere 3 development(GO:0021569)
0.1 0.7 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.2 GO:0050960 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.0 0.1 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.0 0.2 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.2 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.4 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 0.3 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.0 0.1 GO:0043449 cellular alkene metabolic process(GO:0043449)
0.0 0.1 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.0 0.1 GO:0046521 sphingoid catabolic process(GO:0046521)
0.0 0.8 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.3 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.2 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.0 0.3 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.0 0.3 GO:0051511 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 0.1 GO:1990051 activation of protein kinase C activity(GO:1990051)
0.0 0.2 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.3 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.1 GO:0061193 sensory organ boundary specification(GO:0008052) formation of organ boundary(GO:0010160) taste bud development(GO:0061193)
0.0 0.1 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.0 0.7 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.1 GO:0046707 IDP metabolic process(GO:0046707) IDP catabolic process(GO:0046709)
0.0 0.0 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609)
0.0 0.2 GO:0052027 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.0 0.1 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.0 0.1 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.0 0.1 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.2 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.0 0.2 GO:0030822 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.0 0.2 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.0 0.1 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.0 0.1 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.0 0.4 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0 0.2 GO:0006824 cobalt ion transport(GO:0006824)
0.0 0.1 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
0.0 0.3 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.5 GO:0061339 establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.0 0.1 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.1 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877) negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.0 0.3 GO:0036089 cleavage furrow formation(GO:0036089)
0.0 0.6 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.1 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.0 0.1 GO:0034552 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.0 0.1 GO:0006601 creatine biosynthetic process(GO:0006601)
0.0 0.1 GO:0034970 histone H3-R2 methylation(GO:0034970)
0.0 0.5 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.1 GO:1902723 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0 0.1 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.1 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) positive regulation of interleukin-12 secretion(GO:2001184)
0.0 0.3 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.1 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 0.2 GO:0018108 peptidyl-tyrosine phosphorylation(GO:0018108) peptidyl-tyrosine modification(GO:0018212)
0.0 0.1 GO:0018057 peptidyl-lysine oxidation(GO:0018057) negative regulation of T-helper 17 cell lineage commitment(GO:2000329)
0.0 0.7 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.1 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.1 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.3 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.1 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.0 0.8 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 1.0 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.2 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 1.6 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.6 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.2 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.0 0.3 GO:0032869 insulin receptor signaling pathway(GO:0008286) cellular response to insulin stimulus(GO:0032869)
0.0 0.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.1 GO:0018198 peptidyl-cysteine modification(GO:0018198)
0.0 0.2 GO:1902414 protein localization to cell junction(GO:1902414)
0.0 0.1 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.0 0.4 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.9 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.0 0.2 GO:0006868 glutamine transport(GO:0006868) L-cystine transport(GO:0015811)
0.0 0.2 GO:0090343 positive regulation of cell aging(GO:0090343) positive regulation of cellular senescence(GO:2000774)
0.0 0.1 GO:0071362 cellular response to ether(GO:0071362) cellular response to rapamycin(GO:0072752)
0.0 0.4 GO:0015886 heme transport(GO:0015886)
0.0 0.1 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.1 GO:0019230 proprioception(GO:0019230)
0.0 0.4 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.3 GO:0097369 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.2 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.0 0.1 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0 0.3 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.0 0.1 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.0 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.0 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.1 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0 0.9 GO:0097435 fibril organization(GO:0097435)
0.0 0.0 GO:0090472 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.0 0.0 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.1 GO:0035803 egg coat formation(GO:0035803)
0.0 0.0 GO:0060809 mesodermal to mesenchymal transition involved in gastrulation(GO:0060809)
0.0 0.2 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.1 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.3 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.1 GO:0015825 L-serine transport(GO:0015825)
0.0 0.1 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.0 0.1 GO:0030047 actin modification(GO:0030047)
0.0 0.3 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.2 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.6 GO:0060412 ventricular septum morphogenesis(GO:0060412)
0.0 0.1 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 0.2 GO:0007144 female meiosis I(GO:0007144)
0.0 0.2 GO:0048023 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.0 0.2 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.3 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.2 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.0 GO:0036269 swimming behavior(GO:0036269)
0.0 0.3 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.2 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.0 GO:2000807 regulation of synaptic vesicle clustering(GO:2000807)
0.0 0.1 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.3 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:0060539 diaphragm development(GO:0060539)
0.0 0.2 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.1 GO:0032264 IMP salvage(GO:0032264)
0.0 0.0 GO:1904719 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.0 0.2 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.0 0.1 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.0 0.1 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.1 GO:0021678 third ventricle development(GO:0021678)
0.0 0.0 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.7 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.2 1.2 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 0.3 GO:0031523 Myb complex(GO:0031523)
0.0 0.4 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.5 GO:0001940 male pronucleus(GO:0001940)
0.0 0.1 GO:0000814 ESCRT II complex(GO:0000814)
0.0 0.2 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.3 GO:0070435 Shc-EGFR complex(GO:0070435)
0.0 0.1 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.2 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.3 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.1 GO:1990745 EARP complex(GO:1990745)
0.0 0.5 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.2 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.1 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.0 1.7 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 2.1 GO:0031672 A band(GO:0031672)
0.0 0.3 GO:0071953 elastic fiber(GO:0071953)
0.0 0.5 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.0 0.5 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.4 GO:0005916 fascia adherens(GO:0005916)
0.0 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:1990032 parallel fiber(GO:1990032)
0.0 0.3 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.5 GO:0071564 npBAF complex(GO:0071564)
0.0 0.6 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.2 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.7 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.2 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.1 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.2 GO:0000322 storage vacuole(GO:0000322)
0.0 0.2 GO:0030914 STAGA complex(GO:0030914)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.0 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.9 GO:0002102 podosome(GO:0002102)
0.0 0.3 GO:0097440 apical dendrite(GO:0097440)
0.0 0.2 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 0.2 GO:0008091 spectrin(GO:0008091)
0.0 0.1 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.2 0.7 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.1 0.5 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 0.8 GO:0031013 troponin I binding(GO:0031013)
0.1 0.3 GO:0071633 dihydroceramidase activity(GO:0071633)
0.1 0.9 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1 0.4 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.4 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.1 0.4 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 0.9 GO:0045159 myosin II binding(GO:0045159)
0.1 0.2 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.1 0.3 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 0.7 GO:0016015 morphogen activity(GO:0016015)
0.1 0.2 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.1 0.9 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 2.7 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 0.2 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.5 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.1 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0 0.4 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.3 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.7 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:0043849 Ras palmitoyltransferase activity(GO:0043849)
0.0 0.2 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0 0.8 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.2 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.3 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.1 GO:0015067 amidinotransferase activity(GO:0015067) glycine amidinotransferase activity(GO:0015068)
0.0 0.3 GO:0015315 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.1 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.3 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.2 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.1 GO:0031859 platelet activating factor receptor binding(GO:0031859)
0.0 0.3 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.2 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.0 0.2 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0 0.1 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.1 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
0.0 0.3 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.1 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.2 GO:0022858 L-alanine transmembrane transporter activity(GO:0015180) L-proline transmembrane transporter activity(GO:0015193) alanine transmembrane transporter activity(GO:0022858)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 1.5 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0019144 ADP-sugar diphosphatase activity(GO:0019144)
0.0 0.2 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.1 GO:0008193 tRNA guanylyltransferase activity(GO:0008193)
0.0 0.2 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.1 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 1.0 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.1 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 1.8 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.1 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.9 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 1.1 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.1 GO:0004515 nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.1 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.0 0.5 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.2 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.2 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.1 GO:0042835 BRE binding(GO:0042835)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.4 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 0.1 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.4 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.4 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.3 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.0 GO:0019808 polyamine binding(GO:0019808)
0.0 0.2 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.5 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.2 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.3 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.1 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.2 GO:0015197 peptide transporter activity(GO:0015197)
0.0 0.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.7 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.0 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 1.0 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.4 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.0 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.7 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.1 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.5 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.8 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 1.1 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.3 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.2 ST G ALPHA S PATHWAY G alpha s Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.8 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.2 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.5 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.5 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.4 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 1.7 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.4 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.5 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.5 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.6 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.2 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.4 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.7 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.4 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.6 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.5 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.0 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.4 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway