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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for NR1I3

Z-value: 0.28

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Transcription factors associated with NR1I3

Gene Symbol Gene ID Gene Info
NR1I3
ENSG00000143257.7 nuclear receptor subfamily 1 group I member 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR1I3hg19_v2_chr1_-_161207953_161207975-0.522.9e-01Click!

Activity profile of NR1I3 motif

Sorted Z-values of NR1I3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_153330322 0.24 ENST00000368738.3
S100A9
S100 calcium binding protein A9
chr1_-_235116495 0.22 ENST00000549744.1
RP11-443B7.3
RP11-443B7.3
chr14_-_50506589 0.22 ENST00000553914.2
RP11-58E21.3
RP11-58E21.3
chr3_-_71802760 0.17 ENST00000295612.3
EIF4E3
eukaryotic translation initiation factor 4E family member 3
chr12_+_100594557 0.16 ENST00000546902.1
ENST00000552376.1
ENST00000551617.1
ACTR6
ARP6 actin-related protein 6 homolog (yeast)
chr5_-_138780159 0.15 ENST00000512473.1
ENST00000515581.1
ENST00000515277.1
DNAJC18
DnaJ (Hsp40) homolog, subfamily C, member 18
chr9_+_134001455 0.13 ENST00000531584.1
NUP214
nucleoporin 214kDa
chr19_+_2977444 0.12 ENST00000246112.4
ENST00000453329.1
ENST00000482627.1
ENST00000452088.1
TLE6
transducin-like enhancer of split 6 (E(sp1) homolog, Drosophila)
chr17_-_53499310 0.11 ENST00000262065.3
MMD
monocyte to macrophage differentiation-associated
chr1_+_44401479 0.10 ENST00000438616.3
ARTN
artemin
chr6_+_36097992 0.10 ENST00000211287.4
MAPK13
mitogen-activated protein kinase 13
chr5_-_39270725 0.09 ENST00000512138.1
ENST00000512982.1
ENST00000540520.1
FYB
FYN binding protein
chr14_+_53173890 0.09 ENST00000445930.2
PSMC6
proteasome (prosome, macropain) 26S subunit, ATPase, 6
chr14_-_22005062 0.08 ENST00000317492.5
SALL2
spalt-like transcription factor 2
chr14_-_22005197 0.08 ENST00000541965.1
SALL2
spalt-like transcription factor 2
chr4_-_82136114 0.08 ENST00000395578.1
ENST00000418486.2
PRKG2
protein kinase, cGMP-dependent, type II
chr2_+_177015950 0.07 ENST00000306324.3
HOXD4
homeobox D4
chr2_-_69180083 0.07 ENST00000328895.4
GKN2
gastrokine 2
chr12_-_118810688 0.07 ENST00000542532.1
ENST00000392533.3
TAOK3
TAO kinase 3
chr20_+_5987890 0.06 ENST00000378868.4
CRLS1
cardiolipin synthase 1
chr13_+_60971080 0.06 ENST00000377894.2
TDRD3
tudor domain containing 3
chr17_-_53499218 0.06 ENST00000571578.1
MMD
monocyte to macrophage differentiation-associated
chr17_-_62503015 0.06 ENST00000581806.1
DDX5
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr17_-_62502399 0.06 ENST00000450599.2
ENST00000585060.1
DDX5
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr17_+_32582293 0.06 ENST00000580907.1
ENST00000225831.4
CCL2
chemokine (C-C motif) ligand 2
chr1_+_59250815 0.05 ENST00000544621.1
ENST00000419531.2
RP4-794H19.2
long intergenic non-protein coding RNA 1135
chr3_+_122103014 0.05 ENST00000232125.5
ENST00000477892.1
ENST00000469967.1
FAM162A
family with sequence similarity 162, member A
chr17_-_62502639 0.05 ENST00000225792.5
ENST00000581697.1
ENST00000584279.1
ENST00000577922.1
DDX5
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr14_+_53173910 0.05 ENST00000606149.1
ENST00000555339.1
ENST00000556813.1
PSMC6
proteasome (prosome, macropain) 26S subunit, ATPase, 6
chr5_+_52856456 0.05 ENST00000296684.5
ENST00000506765.1
NDUFS4
NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
chr7_-_56160666 0.05 ENST00000297373.2
PHKG1
phosphorylase kinase, gamma 1 (muscle)
chr10_-_73848764 0.05 ENST00000317376.4
ENST00000412663.1
SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr7_-_56160625 0.05 ENST00000446428.1
ENST00000432123.1
ENST00000452681.2
ENST00000537360.1
PHKG1
phosphorylase kinase, gamma 1 (muscle)
chr2_-_209118974 0.05 ENST00000415913.1
ENST00000415282.1
ENST00000446179.1
IDH1
isocitrate dehydrogenase 1 (NADP+), soluble
chr9_-_80646374 0.05 ENST00000286548.4
GNAQ
guanine nucleotide binding protein (G protein), q polypeptide
chr8_-_53626974 0.05 ENST00000435644.2
ENST00000518710.1
ENST00000025008.5
ENST00000517963.1
RB1CC1
RB1-inducible coiled-coil 1
chr11_-_71781096 0.04 ENST00000535087.1
ENST00000535838.1
NUMA1
nuclear mitotic apparatus protein 1
chr15_+_43885252 0.04 ENST00000453782.1
ENST00000300283.6
ENST00000437924.1
ENST00000450086.2
CKMT1B
creatine kinase, mitochondrial 1B
chr10_+_47658234 0.04 ENST00000447511.2
ENST00000537271.1
ANTXRL
anthrax toxin receptor-like
chr19_-_49140692 0.04 ENST00000222122.5
DBP
D site of albumin promoter (albumin D-box) binding protein
chr11_-_61124266 0.04 ENST00000539890.1
CYB561A3
cytochrome b561 family, member A3
chr5_-_135528822 0.04 ENST00000607574.1
AC009014.3
AC009014.3
chr17_-_26695013 0.04 ENST00000555059.2
CTB-96E2.2
Homeobox protein SEBOX
chr1_-_33336414 0.03 ENST00000373471.3
ENST00000609187.1
FNDC5
fibronectin type III domain containing 5
chr6_+_32407619 0.03 ENST00000395388.2
ENST00000374982.5
HLA-DRA
major histocompatibility complex, class II, DR alpha
chr16_-_66968055 0.03 ENST00000568572.1
FAM96B
family with sequence similarity 96, member B
chr6_-_56258892 0.03 ENST00000370819.1
COL21A1
collagen, type XXI, alpha 1
chr17_-_8198636 0.03 ENST00000577745.1
ENST00000579192.1
ENST00000396278.1
SLC25A35
solute carrier family 25, member 35
chr1_-_155159748 0.03 ENST00000473363.2
RP11-201K10.3
RP11-201K10.3
chr12_-_54779511 0.03 ENST00000551109.1
ENST00000546970.1
ZNF385A
zinc finger protein 385A
chr1_+_145516252 0.03 ENST00000369306.3
PEX11B
peroxisomal biogenesis factor 11 beta
chr11_-_71753188 0.03 ENST00000543009.1
NUMA1
nuclear mitotic apparatus protein 1
chr18_-_23670546 0.03 ENST00000542743.1
ENST00000545952.1
ENST00000539849.1
ENST00000415083.2
SS18
synovial sarcoma translocation, chromosome 18
chr19_-_6604094 0.03 ENST00000597430.2
CD70
CD70 molecule
chr17_+_26833250 0.03 ENST00000577936.1
ENST00000579795.1
FOXN1
forkhead box N1
chr18_-_23671139 0.03 ENST00000579061.1
ENST00000542420.2
SS18
synovial sarcoma translocation, chromosome 18
chr1_-_225616515 0.03 ENST00000338179.2
ENST00000425080.1
LBR
lamin B receptor
chr22_+_42372764 0.03 ENST00000396426.3
ENST00000406029.1
SEPT3
septin 3
chr6_+_71276596 0.03 ENST00000370474.3
C6orf57
chromosome 6 open reading frame 57
chr13_-_20806440 0.03 ENST00000400066.3
ENST00000400065.3
ENST00000356192.6
GJB6
gap junction protein, beta 6, 30kDa
chr9_+_5450503 0.03 ENST00000381573.4
ENST00000381577.3
CD274
CD274 molecule
chr19_+_58920102 0.03 ENST00000599238.1
ENST00000322834.7
ZNF584
zinc finger protein 584
chrX_+_110924346 0.02 ENST00000371979.3
ENST00000251943.4
ENST00000486353.1
ENST00000394780.3
ENST00000495283.1
ALG13
ALG13, UDP-N-acetylglucosaminyltransferase subunit
chr9_-_75567962 0.02 ENST00000297785.3
ENST00000376939.1
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr8_-_143833918 0.02 ENST00000359228.3
LYPD2
LY6/PLAUR domain containing 2
chr3_-_58419537 0.02 ENST00000474765.1
ENST00000485460.1
ENST00000302746.6
ENST00000383714.4
PDHB
pyruvate dehydrogenase (lipoamide) beta
chr14_+_21525981 0.02 ENST00000308227.2
RNASE8
ribonuclease, RNase A family, 8
chr1_-_21625486 0.02 ENST00000481130.2
ECE1
endothelin converting enzyme 1
chr19_-_44306590 0.02 ENST00000377950.3
LYPD5
LY6/PLAUR domain containing 5
chr6_+_96969672 0.02 ENST00000369278.4
UFL1
UFM1-specific ligase 1
chr8_+_11351876 0.02 ENST00000529894.1
BLK
B lymphoid tyrosine kinase
chr10_+_47657581 0.02 ENST00000441923.2
ANTXRL
anthrax toxin receptor-like
chr6_+_108487245 0.02 ENST00000368986.4
NR2E1
nuclear receptor subfamily 2, group E, member 1
chr11_-_82611448 0.02 ENST00000393399.2
ENST00000313010.3
PRCP
prolylcarboxypeptidase (angiotensinase C)
chr19_-_46285646 0.02 ENST00000458663.2
DMPK
dystrophia myotonica-protein kinase
chr12_-_53729525 0.01 ENST00000303846.3
SP7
Sp7 transcription factor
chr1_+_82165350 0.01 ENST00000359929.3
LPHN2
latrophilin 2
chrX_+_118602363 0.01 ENST00000317881.8
SLC25A5
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
chr13_-_114107839 0.01 ENST00000375418.3
ADPRHL1
ADP-ribosylhydrolase like 1
chr14_-_22005018 0.01 ENST00000546363.1
SALL2
spalt-like transcription factor 2
chr13_+_24883703 0.01 ENST00000332018.4
C1QTNF9
C1q and tumor necrosis factor related protein 9
chr1_+_145516560 0.01 ENST00000537888.1
PEX11B
peroxisomal biogenesis factor 11 beta
chr15_+_43985084 0.01 ENST00000434505.1
ENST00000411750.1
CKMT1A
creatine kinase, mitochondrial 1A
chr19_-_48894104 0.01 ENST00000597017.1
KDELR1
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
chr1_-_20755140 0.01 ENST00000418743.1
ENST00000426428.1
RP4-749H3.1
long intergenic non-protein coding RNA 1141
chr7_-_99381884 0.01 ENST00000336411.2
CYP3A4
cytochrome P450, family 3, subfamily A, polypeptide 4
chr1_+_160097462 0.01 ENST00000447527.1
ATP1A2
ATPase, Na+/K+ transporting, alpha 2 polypeptide
chr5_-_176936817 0.01 ENST00000502885.1
ENST00000506493.1
DOK3
docking protein 3
chr1_+_32930647 0.01 ENST00000609129.1
ZBTB8B
zinc finger and BTB domain containing 8B
chr19_-_49140609 0.01 ENST00000601104.1
DBP
D site of albumin promoter (albumin D-box) binding protein
chr12_-_108991812 0.01 ENST00000392806.3
ENST00000547567.1
TMEM119
transmembrane protein 119
chr17_-_33390667 0.01 ENST00000378516.2
ENST00000268850.7
ENST00000394597.2
RFFL
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr22_+_39493268 0.01 ENST00000401756.1
APOBEC3H
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H
chr9_+_34179003 0.01 ENST00000545103.1
ENST00000543944.1
ENST00000536252.1
ENST00000540348.1
ENST00000297661.4
ENST00000379186.4
UBAP1
ubiquitin associated protein 1
chr4_-_57524061 0.00 ENST00000508121.1
HOPX
HOP homeobox
chrX_-_50386648 0.00 ENST00000460112.3
SHROOM4
shroom family member 4
chr17_-_26694979 0.00 ENST00000438614.1
VTN
vitronectin
chr3_-_116163830 0.00 ENST00000333617.4
LSAMP
limbic system-associated membrane protein
chr1_-_32210275 0.00 ENST00000440175.2
BAI2
brain-specific angiogenesis inhibitor 2
chr1_+_113217043 0.00 ENST00000413052.2
MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr12_-_75601778 0.00 ENST00000550433.1
ENST00000548513.1
KCNC2
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr1_-_205290865 0.00 ENST00000367157.3
NUAK2
NUAK family, SNF1-like kinase, 2
chr10_+_88414338 0.00 ENST00000241891.5
ENST00000443292.1
OPN4
opsin 4
chr16_-_16317321 0.00 ENST00000205557.7
ENST00000575728.1
ABCC6
ATP-binding cassette, sub-family C (CFTR/MRP), member 6
chrX_+_69674943 0.00 ENST00000542398.1
DLG3
discs, large homolog 3 (Drosophila)
chr19_-_9968816 0.00 ENST00000590841.1
OLFM2
olfactomedin 2
chr9_+_75766763 0.00 ENST00000456643.1
ENST00000415424.1
ANXA1
annexin A1
chr2_-_241075706 0.00 ENST00000607357.1
ENST00000307266.3
MYEOV2
myeloma overexpressed 2
chr1_+_15250596 0.00 ENST00000361144.5
KAZN
kazrin, periplakin interacting protein
chr6_-_127780510 0.00 ENST00000487331.2
ENST00000483725.3
KIAA0408
KIAA0408
chr8_-_52721975 0.00 ENST00000356297.4
ENST00000543296.1
PXDNL
peroxidasin homolog (Drosophila)-like
chr15_-_42343388 0.00 ENST00000399518.3
PLA2G4E
phospholipase A2, group IVE

Network of associatons between targets according to the STRING database.

First level regulatory network of NR1I3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.0 0.1 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.0 0.1 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.0 0.1 GO:0097021 lymphocyte migration into lymphoid organs(GO:0097021)
0.0 0.0 GO:0006097 glyoxylate cycle(GO:0006097)
0.0 0.1 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.1 GO:0031595 nuclear proteasome complex(GO:0031595)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.2 GO:0004672 protein kinase activity(GO:0004672)
0.0 0.1 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.0 0.2 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.0 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)