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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for NR1I2

Z-value: 0.75

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Transcription factors associated with NR1I2

Gene Symbol Gene ID Gene Info
NR1I2
ENSG00000144852.12 nuclear receptor subfamily 1 group I member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR1I2hg19_v2_chr3_+_119499331_119499331-0.691.3e-01Click!

Activity profile of NR1I2 motif

Sorted Z-values of NR1I2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_12679171 0.79 ENST00000606790.1
RP11-474O21.5
RP11-474O21.5
chr9_-_139981121 0.57 ENST00000596585.1
AL807752.1
Uncharacterized protein
chr1_+_229440129 0.49 ENST00000366688.3
SPHAR
S-phase response (cyclin related)
chr8_-_1922789 0.42 ENST00000521498.1
RP11-439C15.4
RP11-439C15.4
chr10_+_77056181 0.42 ENST00000526759.1
ENST00000533822.1
ZNF503-AS1
ZNF503 antisense RNA 1
chr3_+_11267691 0.40 ENST00000413416.1
HRH1
histamine receptor H1
chr22_+_22676808 0.35 ENST00000390290.2
IGLV1-51
immunoglobulin lambda variable 1-51
chr1_+_15479054 0.34 ENST00000376014.3
ENST00000451326.2
TMEM51
transmembrane protein 51
chr16_+_83986827 0.33 ENST00000393306.1
ENST00000565123.1
OSGIN1
oxidative stress induced growth inhibitor 1
chr16_-_4164027 0.33 ENST00000572288.1
ADCY9
adenylate cyclase 9
chr14_+_73706308 0.33 ENST00000554301.1
ENST00000555445.1
PAPLN
papilin, proteoglycan-like sulfated glycoprotein
chr19_-_38878632 0.31 ENST00000586599.1
ENST00000334928.6
ENST00000587676.1
GGN
gametogenetin
chr19_-_44008863 0.30 ENST00000601646.1
PHLDB3
pleckstrin homology-like domain, family B, member 3
chr3_-_196065248 0.30 ENST00000446879.1
ENST00000273695.3
TM4SF19
transmembrane 4 L six family member 19
chr7_-_86848933 0.29 ENST00000423734.1
TMEM243
transmembrane protein 243, mitochondrial
chr4_+_22999152 0.29 ENST00000511453.1
RP11-412P11.1
RP11-412P11.1
chr9_-_140115775 0.29 ENST00000391553.1
ENST00000392827.1
RNF208
ring finger protein 208
chr19_-_36304201 0.29 ENST00000301175.3
PRODH2
proline dehydrogenase (oxidase) 2
chr17_-_46682321 0.29 ENST00000225648.3
ENST00000484302.2
HOXB6
homeobox B6
chr14_-_65769392 0.28 ENST00000555736.1
CTD-2509G16.5
CTD-2509G16.5
chr9_-_118417 0.28 ENST00000382500.2
FOXD4
forkhead box D4
chr19_-_39303576 0.28 ENST00000594209.1
LGALS4
lectin, galactoside-binding, soluble, 4
chr16_+_30710462 0.27 ENST00000262518.4
ENST00000395059.2
ENST00000344771.4
SRCAP
Snf2-related CREBBP activator protein
chr1_+_15479021 0.27 ENST00000428417.1
TMEM51
transmembrane protein 51
chr17_-_7531121 0.27 ENST00000573566.1
ENST00000269298.5
SAT2
spermidine/spermine N1-acetyltransferase family member 2
chr4_+_71600063 0.26 ENST00000513597.1
RUFY3
RUN and FYVE domain containing 3
chr6_+_147981838 0.26 ENST00000427015.1
ENST00000432506.1
RP11-307P5.1
RP11-307P5.1
chr19_-_3547305 0.26 ENST00000589063.1
MFSD12
major facilitator superfamily domain containing 12
chr2_+_114256661 0.26 ENST00000306507.5
FOXD4L1
forkhead box D4-like 1
chr6_+_73331918 0.26 ENST00000402622.2
ENST00000355635.3
ENST00000403813.2
ENST00000414165.2
KCNQ5
potassium voltage-gated channel, KQT-like subfamily, member 5
chr19_+_10947251 0.26 ENST00000592854.1
C19orf38
chromosome 19 open reading frame 38
chr16_-_4466565 0.25 ENST00000572467.1
ENST00000423908.2
ENST00000572044.1
ENST00000571052.1
CORO7-PAM16
CORO7
CORO7-PAM16 readthrough
coronin 7
chr11_+_117073850 0.25 ENST00000529622.1
TAGLN
transgelin
chr8_-_9009079 0.25 ENST00000519699.1
PPP1R3B
protein phosphatase 1, regulatory subunit 3B
chr16_-_88752889 0.25 ENST00000332281.5
SNAI3
snail family zinc finger 3
chr16_+_28875126 0.24 ENST00000359285.5
ENST00000538342.1
SH2B1
SH2B adaptor protein 1
chr5_+_139055055 0.24 ENST00000511457.1
CXXC5
CXXC finger protein 5
chr5_-_154230130 0.24 ENST00000519501.1
ENST00000518651.1
ENST00000517938.1
ENST00000520461.1
FAXDC2
fatty acid hydroxylase domain containing 2
chr16_+_28874345 0.24 ENST00000566209.1
SH2B1
SH2B adaptor protein 1
chr15_+_96876340 0.24 ENST00000453270.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr12_-_6665200 0.23 ENST00000336604.4
ENST00000396840.2
ENST00000356896.4
IFFO1
intermediate filament family orphan 1
chr9_+_21440440 0.23 ENST00000276927.1
IFNA1
interferon, alpha 1
chr1_+_43291220 0.23 ENST00000372514.3
ERMAP
erythroblast membrane-associated protein (Scianna blood group)
chr16_-_15950868 0.22 ENST00000396324.3
ENST00000452625.2
ENST00000576790.2
ENST00000300036.5
MYH11
myosin, heavy chain 11, smooth muscle
chr6_-_32977345 0.22 ENST00000450833.2
ENST00000374813.1
ENST00000229829.5
HLA-DOA
major histocompatibility complex, class II, DO alpha
chr13_+_24844857 0.22 ENST00000409126.1
ENST00000343003.6
SPATA13
spermatogenesis associated 13
chr3_+_193853927 0.22 ENST00000232424.3
HES1
hes family bHLH transcription factor 1
chr11_+_118478313 0.22 ENST00000356063.5
PHLDB1
pleckstrin homology-like domain, family B, member 1
chr13_+_24844819 0.21 ENST00000399949.2
SPATA13
spermatogenesis associated 13
chr21_-_44751903 0.21 ENST00000450205.1
LINC00322
long intergenic non-protein coding RNA 322
chr11_+_66624527 0.21 ENST00000393952.3
LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr6_+_12007963 0.21 ENST00000607445.1
RP11-456H18.2
RP11-456H18.2
chr17_-_33448468 0.21 ENST00000591723.1
ENST00000593039.1
ENST00000587405.1
RAD51L3-RFFL
RAD51D
Uncharacterized protein
RAD51 paralog D
chr3_-_9994021 0.21 ENST00000411976.2
ENST00000412055.1
PRRT3
proline-rich transmembrane protein 3
chr12_+_117176113 0.21 ENST00000319176.7
RNFT2
ring finger protein, transmembrane 2
chr7_-_150777920 0.21 ENST00000353841.2
ENST00000297532.6
FASTK
Fas-activated serine/threonine kinase
chr6_-_34664612 0.21 ENST00000374023.3
ENST00000374026.3
C6orf106
chromosome 6 open reading frame 106
chr6_-_152623231 0.21 ENST00000540663.1
ENST00000537033.1
SYNE1
spectrin repeat containing, nuclear envelope 1
chr19_-_43690674 0.21 ENST00000342951.6
ENST00000366175.3
PSG5
pregnancy specific beta-1-glycoprotein 5
chr4_+_71600144 0.21 ENST00000502653.1
RUFY3
RUN and FYVE domain containing 3
chr3_-_178969403 0.21 ENST00000314235.5
ENST00000392685.2
KCNMB3
potassium large conductance calcium-activated channel, subfamily M beta member 3
chr16_+_58498194 0.20 ENST00000561779.1
ENST00000565430.1
ENST00000567063.1
ENST00000566041.1
NDRG4
NDRG family member 4
chr19_-_51289374 0.20 ENST00000563228.1
CTD-2568A17.1
CTD-2568A17.1
chr1_-_55089191 0.20 ENST00000302250.2
ENST00000371304.2
FAM151A
family with sequence similarity 151, member A
chr12_+_120875910 0.20 ENST00000551806.1
AL021546.6
Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial
chr2_-_31440377 0.20 ENST00000444918.2
ENST00000403897.3
CAPN14
calpain 14
chr16_-_58328923 0.20 ENST00000567164.1
ENST00000219301.4
ENST00000569727.1
PRSS54
protease, serine, 54
chr1_+_12538594 0.20 ENST00000543710.1
VPS13D
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr16_-_28937027 0.19 ENST00000358201.4
RABEP2
rabaptin, RAB GTPase binding effector protein 2
chr10_-_103347883 0.19 ENST00000339310.3
ENST00000370158.3
ENST00000299206.4
ENST00000456836.2
ENST00000413344.1
ENST00000429502.1
ENST00000430045.1
ENST00000370172.1
ENST00000436284.2
ENST00000370162.3
POLL
polymerase (DNA directed), lambda
chr2_+_30455016 0.19 ENST00000401506.1
ENST00000407930.2
LBH
limb bud and heart development
chr20_+_62492566 0.19 ENST00000369916.3
ABHD16B
abhydrolase domain containing 16B
chr3_+_8543393 0.19 ENST00000157600.3
ENST00000415597.1
ENST00000535732.1
LMCD1
LIM and cysteine-rich domains 1
chr2_+_109223595 0.19 ENST00000410093.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr5_-_158757895 0.19 ENST00000231228.2
IL12B
interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
chr11_-_134095335 0.18 ENST00000534227.1
ENST00000532445.1
NCAPD3
non-SMC condensin II complex, subunit D3
chr18_+_3466248 0.18 ENST00000581029.1
ENST00000581442.1
ENST00000579007.1
RP11-838N2.4
RP11-838N2.4
chr11_+_107461948 0.18 ENST00000265840.7
ENST00000443271.2
ELMOD1
ELMO/CED-12 domain containing 1
chrX_-_30327495 0.18 ENST00000453287.1
NR0B1
nuclear receptor subfamily 0, group B, member 1
chr16_+_84209539 0.18 ENST00000569735.1
DNAAF1
dynein, axonemal, assembly factor 1
chr7_-_150777949 0.18 ENST00000482571.1
FASTK
Fas-activated serine/threonine kinase
chr7_-_56174161 0.18 ENST00000395422.3
CHCHD2
coiled-coil-helix-coiled-coil-helix domain containing 2
chr8_+_99956662 0.18 ENST00000523368.1
ENST00000297565.4
ENST00000435298.2
OSR2
odd-skipped related transciption factor 2
chr14_-_95236551 0.18 ENST00000238558.3
GSC
goosecoid homeobox
chr20_+_3776371 0.18 ENST00000245960.5
CDC25B
cell division cycle 25B
chr2_+_242127924 0.18 ENST00000402530.3
ENST00000274979.8
ENST00000402430.3
ANO7
anoctamin 7
chr3_+_8543533 0.17 ENST00000454244.1
LMCD1
LIM and cysteine-rich domains 1
chr22_+_50354104 0.17 ENST00000360612.4
PIM3
pim-3 oncogene
chr5_+_139055021 0.17 ENST00000502716.1
ENST00000503511.1
CXXC5
CXXC finger protein 5
chr19_+_39616410 0.17 ENST00000602004.1
ENST00000599470.1
ENST00000321944.4
ENST00000593480.1
ENST00000358301.3
ENST00000593690.1
ENST00000599386.1
PAK4
p21 protein (Cdc42/Rac)-activated kinase 4
chr14_+_23340822 0.17 ENST00000359591.4
LRP10
low density lipoprotein receptor-related protein 10
chr7_-_149158187 0.17 ENST00000247930.4
ZNF777
zinc finger protein 777
chr5_+_1801503 0.17 ENST00000274137.5
ENST00000469176.1
NDUFS6
NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase)
chr15_+_42696992 0.17 ENST00000561817.1
CAPN3
calpain 3, (p94)
chr6_+_158733692 0.17 ENST00000367094.2
ENST00000367097.3
TULP4
tubby like protein 4
chr3_-_185826286 0.17 ENST00000537818.1
ENST00000422039.1
ENST00000434744.1
ETV5
ets variant 5
chr12_-_124873357 0.16 ENST00000448614.1
NCOR2
nuclear receptor corepressor 2
chr16_+_29991673 0.16 ENST00000416441.2
TAOK2
TAO kinase 2
chr20_+_19870167 0.16 ENST00000440354.2
RIN2
Ras and Rab interactor 2
chr10_+_24755416 0.16 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217
KIAA1217
chr14_+_64565442 0.16 ENST00000553308.1
SYNE2
spectrin repeat containing, nuclear envelope 2
chr17_-_4852332 0.16 ENST00000572383.1
PFN1
profilin 1
chr1_+_156589051 0.16 ENST00000255039.1
HAPLN2
hyaluronan and proteoglycan link protein 2
chr2_+_109237717 0.16 ENST00000409441.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr6_+_43738444 0.16 ENST00000324450.6
ENST00000417285.2
ENST00000413642.3
ENST00000372055.4
ENST00000482630.2
ENST00000425836.2
ENST00000372064.4
ENST00000372077.4
ENST00000519767.1
VEGFA
vascular endothelial growth factor A
chr1_+_223101757 0.16 ENST00000284476.6
DISP1
dispatched homolog 1 (Drosophila)
chr8_+_99956759 0.16 ENST00000522510.1
ENST00000457907.2
OSR2
odd-skipped related transciption factor 2
chr1_+_156589198 0.16 ENST00000456112.1
HAPLN2
hyaluronan and proteoglycan link protein 2
chr1_-_151299842 0.16 ENST00000438243.2
ENST00000489223.2
ENST00000368873.1
ENST00000430800.1
ENST00000368872.1
PI4KB
phosphatidylinositol 4-kinase, catalytic, beta
chr22_+_46546406 0.16 ENST00000440343.1
ENST00000415785.1
PPARA
peroxisome proliferator-activated receptor alpha
chr7_-_131241361 0.16 ENST00000378555.3
ENST00000322985.9
ENST00000541194.1
ENST00000537928.1
PODXL
podocalyxin-like
chr2_-_75426183 0.16 ENST00000409848.3
TACR1
tachykinin receptor 1
chr2_-_200335983 0.16 ENST00000457245.1
SATB2
SATB homeobox 2
chr4_-_152682129 0.16 ENST00000512306.1
ENST00000508611.1
ENST00000515812.1
ENST00000263985.6
PET112
PET112 homolog (yeast)
chr4_-_110723134 0.16 ENST00000510800.1
ENST00000512148.1
CFI
complement factor I
chr2_-_69870835 0.16 ENST00000409085.4
ENST00000406297.3
AAK1
AP2 associated kinase 1
chr21_+_43823983 0.16 ENST00000291535.6
ENST00000450356.1
ENST00000319294.6
ENST00000398367.1
UBASH3A
ubiquitin associated and SH3 domain containing A
chr3_+_8543561 0.16 ENST00000397386.3
LMCD1
LIM and cysteine-rich domains 1
chr19_+_9251052 0.15 ENST00000247956.6
ENST00000360385.3
ZNF317
zinc finger protein 317
chr11_+_62649158 0.15 ENST00000539891.1
ENST00000536981.1
SLC3A2
solute carrier family 3 (amino acid transporter heavy chain), member 2
chrX_+_49832231 0.15 ENST00000376108.3
CLCN5
chloride channel, voltage-sensitive 5
chr9_-_14314066 0.15 ENST00000397575.3
NFIB
nuclear factor I/B
chr6_-_53013620 0.15 ENST00000259803.7
GCM1
glial cells missing homolog 1 (Drosophila)
chr16_-_2770216 0.15 ENST00000302641.3
PRSS27
protease, serine 27
chr3_-_196065374 0.15 ENST00000454715.1
TM4SF19
transmembrane 4 L six family member 19
chr22_-_43567750 0.15 ENST00000494035.1
TTLL12
tubulin tyrosine ligase-like family, member 12
chr7_-_105332084 0.15 ENST00000472195.1
ATXN7L1
ataxin 7-like 1
chr2_+_30454390 0.15 ENST00000395323.3
ENST00000406087.1
ENST00000404397.1
LBH
limb bud and heart development
chr19_+_36236514 0.15 ENST00000222266.2
PSENEN
presenilin enhancer gamma secretase subunit
chr2_+_233734994 0.15 ENST00000331342.2
C2orf82
chromosome 2 open reading frame 82
chr13_-_95364389 0.15 ENST00000376945.2
SOX21
SRY (sex determining region Y)-box 21
chr14_-_76447336 0.15 ENST00000556285.1
TGFB3
transforming growth factor, beta 3
chr4_+_113970772 0.15 ENST00000504454.1
ENST00000394537.3
ENST00000357077.4
ENST00000264366.6
ANK2
ankyrin 2, neuronal
chr1_-_54879140 0.15 ENST00000525990.1
SSBP3
single stranded DNA binding protein 3
chr15_-_89438742 0.15 ENST00000562281.1
ENST00000562889.1
ENST00000359595.3
HAPLN3
hyaluronan and proteoglycan link protein 3
chr6_-_138893661 0.15 ENST00000427025.2
NHSL1
NHS-like 1
chr4_-_120243545 0.14 ENST00000274024.3
FABP2
fatty acid binding protein 2, intestinal
chr16_+_1832902 0.14 ENST00000262302.9
ENST00000563136.1
ENST00000565987.1
ENST00000543305.1
ENST00000568287.1
ENST00000565134.1
NUBP2
nucleotide binding protein 2
chr1_-_229569834 0.14 ENST00000366684.3
ENST00000366683.2
ACTA1
actin, alpha 1, skeletal muscle
chr9_+_35829208 0.14 ENST00000439587.2
ENST00000377991.4
TMEM8B
transmembrane protein 8B
chr1_-_205091115 0.14 ENST00000264515.6
ENST00000367164.1
RBBP5
retinoblastoma binding protein 5
chr9_-_34620440 0.14 ENST00000421919.1
ENST00000378911.3
ENST00000477738.2
ENST00000341694.2
ENST00000259632.7
ENST00000378913.2
ENST00000378916.4
ENST00000447983.2
DCTN3
dynactin 3 (p22)
chr19_+_11039391 0.14 ENST00000270502.6
C19orf52
chromosome 19 open reading frame 52
chr9_-_73483926 0.14 ENST00000396283.1
ENST00000361823.5
TRPM3
transient receptor potential cation channel, subfamily M, member 3
chr7_+_97910962 0.14 ENST00000539286.1
BRI3
brain protein I3
chr1_+_201979645 0.14 ENST00000367284.5
ENST00000367283.3
ELF3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr10_-_76995675 0.14 ENST00000469299.1
COMTD1
catechol-O-methyltransferase domain containing 1
chr15_+_59730348 0.14 ENST00000288228.5
ENST00000559628.1
ENST00000557914.1
ENST00000560474.1
FAM81A
family with sequence similarity 81, member A
chr2_-_69870747 0.14 ENST00000409068.1
AAK1
AP2 associated kinase 1
chr16_-_79804435 0.14 ENST00000562921.1
ENST00000566729.1
RP11-345M22.2
RP11-345M22.2
chr1_+_36621174 0.14 ENST00000429533.2
MAP7D1
MAP7 domain containing 1
chr1_-_53387386 0.14 ENST00000467988.1
ENST00000358358.5
ENST00000371522.4
ECHDC2
enoyl CoA hydratase domain containing 2
chr4_-_110723194 0.14 ENST00000394635.3
CFI
complement factor I
chr3_-_123123407 0.14 ENST00000466617.1
ADCY5
adenylate cyclase 5
chr10_-_105677427 0.14 ENST00000369764.1
OBFC1
oligonucleotide/oligosaccharide-binding fold containing 1
chr12_-_52585765 0.14 ENST00000313234.5
ENST00000394815.2
KRT80
keratin 80
chr14_+_100532771 0.14 ENST00000557153.1
EVL
Enah/Vasp-like
chr8_+_21911054 0.13 ENST00000519850.1
ENST00000381470.3
DMTN
dematin actin binding protein
chr1_+_145209092 0.13 ENST00000362074.6
ENST00000344859.3
NOTCH2NL
notch 2 N-terminal like
chr2_-_74779744 0.13 ENST00000409249.1
LOXL3
lysyl oxidase-like 3
chr2_-_86790593 0.13 ENST00000263856.4
ENST00000409225.2
CHMP3
charged multivesicular body protein 3
chr15_-_43212836 0.13 ENST00000566931.1
ENST00000564431.1
ENST00000567274.1
TTBK2
tau tubulin kinase 2
chr19_-_45657028 0.13 ENST00000429338.1
ENST00000589776.1
NKPD1
NTPase, KAP family P-loop domain containing 1
chr9_+_139981513 0.13 ENST00000535144.1
ENST00000542372.1
MAN1B1
mannosidase, alpha, class 1B, member 1
chr1_-_144994840 0.13 ENST00000369351.3
ENST00000369349.3
PDE4DIP
phosphodiesterase 4D interacting protein
chr19_-_10946871 0.12 ENST00000589638.1
TMED1
transmembrane emp24 protein transport domain containing 1
chr17_-_14683517 0.12 ENST00000379640.1
AC005863.1
AC005863.1
chr1_+_201979743 0.12 ENST00000446188.1
ELF3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr5_-_158526756 0.12 ENST00000313708.6
ENST00000517373.1
EBF1
early B-cell factor 1
chr3_-_114343039 0.12 ENST00000481632.1
ZBTB20
zinc finger and BTB domain containing 20
chr13_-_30424821 0.12 ENST00000380680.4
UBL3
ubiquitin-like 3
chr12_+_57854274 0.12 ENST00000528432.1
GLI1
GLI family zinc finger 1
chr1_+_110754094 0.12 ENST00000369787.3
ENST00000413138.3
ENST00000438661.2
KCNC4
potassium voltage-gated channel, Shaw-related subfamily, member 4
chr19_-_12845467 0.12 ENST00000592273.1
ENST00000588213.1
C19orf43
chromosome 19 open reading frame 43
chr22_+_25003568 0.12 ENST00000447416.1
GGT1
gamma-glutamyltransferase 1
chr11_+_62648336 0.12 ENST00000338663.7
SLC3A2
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr1_+_24646263 0.12 ENST00000524724.1
GRHL3
grainyhead-like 3 (Drosophila)
chr1_-_149814478 0.12 ENST00000369161.3
HIST2H2AA3
histone cluster 2, H2aa3
chr1_+_32379174 0.12 ENST00000391369.1
AL136115.1
HCG2032337; PRO1848; Uncharacterized protein
chr9_-_130966497 0.12 ENST00000393608.1
ENST00000372948.3
CIZ1
CDKN1A interacting zinc finger protein 1
chr6_-_27782548 0.12 ENST00000333151.3
HIST1H2AJ
histone cluster 1, H2aj
chr19_-_12845550 0.12 ENST00000242784.4
C19orf43
chromosome 19 open reading frame 43
chr7_-_111424462 0.12 ENST00000437129.1
DOCK4
dedicator of cytokinesis 4
chr15_+_96875657 0.12 ENST00000559679.1
ENST00000394171.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr3_-_117716418 0.12 ENST00000484092.1
RP11-384F7.2
RP11-384F7.2
chr18_+_29027696 0.11 ENST00000257189.4
DSG3
desmoglein 3
chr17_-_2169425 0.11 ENST00000570606.1
ENST00000354901.4
SMG6
SMG6 nonsense mediated mRNA decay factor
chr6_+_37897735 0.11 ENST00000373389.5
ZFAND3
zinc finger, AN1-type domain 3
chr3_+_14989186 0.11 ENST00000435454.1
ENST00000323373.6
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr8_-_29120580 0.11 ENST00000524189.1
KIF13B
kinesin family member 13B
chr2_+_97426631 0.11 ENST00000377075.2
CNNM4
cyclin M4
chr17_-_9929581 0.11 ENST00000437099.2
ENST00000396115.2
GAS7
growth arrest-specific 7
chr11_-_111794446 0.11 ENST00000527950.1
CRYAB
crystallin, alpha B
chr3_+_69985734 0.11 ENST00000314557.6
ENST00000394351.3
MITF
microphthalmia-associated transcription factor
chr3_+_183894737 0.11 ENST00000432591.1
ENST00000431779.1
AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr9_+_139981379 0.11 ENST00000371589.4
MAN1B1
mannosidase, alpha, class 1B, member 1
chr6_+_45296048 0.11 ENST00000465038.2
ENST00000352853.5
ENST00000541979.1
ENST00000371438.1
RUNX2
runt-related transcription factor 2
chr5_+_73109339 0.11 ENST00000296799.4
ARHGEF28
Rho guanine nucleotide exchange factor (GEF) 28
chr8_+_86999516 0.11 ENST00000521564.1
ATP6V0D2
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
chr14_-_73493825 0.11 ENST00000318876.5
ENST00000556143.1
ZFYVE1
zinc finger, FYVE domain containing 1

Network of associatons between targets according to the STRING database.

First level regulatory network of NR1I2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.1 0.4 GO:0009447 putrescine catabolic process(GO:0009447)
0.1 0.4 GO:0009956 radial pattern formation(GO:0009956)
0.1 0.2 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.1 0.2 GO:0045632 negative regulation of auditory receptor cell differentiation(GO:0045608) negative regulation of mechanoreceptor differentiation(GO:0045632) negative regulation of inner ear receptor cell differentiation(GO:2000981)
0.1 0.2 GO:0072361 regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361)
0.1 0.2 GO:0014876 response to injury involved in regulation of muscle adaptation(GO:0014876)
0.1 0.2 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.1 0.3 GO:1904674 positive regulation of somatic stem cell population maintenance(GO:1904674)
0.1 0.2 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.1 0.2 GO:1903570 coronary vein morphogenesis(GO:0003169) regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.1 0.3 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.1 0.2 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1 0.2 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051)
0.0 0.3 GO:0060356 leucine import(GO:0060356)
0.0 0.1 GO:2000742 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.0 0.3 GO:0036022 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.0 0.2 GO:0036511 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.0 0.2 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536)
0.0 0.4 GO:0032962 positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.0 0.3 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.3 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 0.2 GO:0060018 astrocyte fate commitment(GO:0060018)
0.0 0.1 GO:0061009 common bile duct development(GO:0061009)
0.0 0.1 GO:1903762 regulation of heart looping(GO:1901207) positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903762) positive regulation of ventricular cardiac muscle cell action potential(GO:1903947) positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905026) positive regulation of membrane repolarization during cardiac muscle cell action potential(GO:1905033)
0.0 0.2 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.1 GO:0060032 notochord regression(GO:0060032)
0.0 0.1 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.1 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.0 0.1 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.0 0.1 GO:0018057 peptidyl-lysine oxidation(GO:0018057) negative regulation of T-helper 17 cell lineage commitment(GO:2000329)
0.0 0.1 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.2 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.3 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.0 0.1 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.0 0.1 GO:0071423 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.0 0.3 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.1 GO:0030240 skeletal muscle thin filament assembly(GO:0030240) mesenchyme migration(GO:0090131)
0.0 0.1 GO:0007346 regulation of mitotic cell cycle(GO:0007346)
0.0 0.2 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.2 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.1 GO:1903028 positive regulation of opsonization(GO:1903028)
0.0 0.2 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.0 0.2 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.2 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 0.2 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.1 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.3 GO:0007144 female meiosis I(GO:0007144)
0.0 0.1 GO:0006059 hexitol metabolic process(GO:0006059)
0.0 0.2 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.0 0.1 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.0 0.5 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.2 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.1 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.1 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.1 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.0 0.1 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894) cellular alkene metabolic process(GO:0043449)
0.0 0.2 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.3 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.1 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387) epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.0 0.2 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.1 GO:0070560 protein secretion by platelet(GO:0070560)
0.0 0.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.1 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.2 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 0.2 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0033686 positive regulation of luteinizing hormone secretion(GO:0033686)
0.0 0.2 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.2 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 0.0 GO:2001113 negative regulation of hepatocyte growth factor receptor signaling pathway(GO:1902203) regulation of cellular response to hepatocyte growth factor stimulus(GO:2001112) negative regulation of cellular response to hepatocyte growth factor stimulus(GO:2001113)
0.0 0.5 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.1 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0 0.1 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.0 0.1 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.2 GO:0030238 male sex determination(GO:0030238)
0.0 0.2 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.0 0.2 GO:0014029 neural crest formation(GO:0014029)
0.0 0.1 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.0 GO:0014846 esophagus smooth muscle contraction(GO:0014846)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.0 0.2 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.2 GO:0000799 nuclear condensin complex(GO:0000799)
0.0 0.2 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.1 GO:0070069 cytochrome complex(GO:0070069)
0.0 0.1 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.0 0.2 GO:0031906 late endosome lumen(GO:0031906)
0.0 0.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.3 GO:0042587 glycogen granule(GO:0042587)
0.0 0.2 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.0 GO:0098855 HCN channel complex(GO:0098855)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.4 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.4 GO:0071437 invadopodium(GO:0071437)
0.0 0.2 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.3 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.2 GO:0032982 myosin filament(GO:0032982)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.1 0.3 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.1 0.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 0.3 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.1 0.2 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 0.1 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.0 0.3 GO:0016936 galactoside binding(GO:0016936)
0.0 0.2 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.4 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.0 0.1 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.0 0.2 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.2 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.1 GO:0015131 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.0 0.1 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.1 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.2 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.3 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.3 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.2 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.2 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.2 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.2 GO:0035877 death effector domain binding(GO:0035877)
0.0 0.3 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.1 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.1 GO:0004945 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0004335 galactokinase activity(GO:0004335)
0.0 0.0 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.0 0.2 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.1 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.5 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.5 NABA PROTEOGLYCANS Genes encoding proteoglycans

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.6 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.3 REACTOME SIGNALING BY NOTCH2 Genes involved in Signaling by NOTCH2
0.0 0.4 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.3 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition