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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for NKX2-6

Z-value: 1.00

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Transcription factors associated with NKX2-6

Gene Symbol Gene ID Gene Info
NKX2-6
ENSG00000180053.6 NK2 homeobox 6

Activity profile of NKX2-6 motif

Sorted Z-values of NKX2-6 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_187367356 0.99 ENST00000595956.1
AC018867.2
AC018867.2
chr3_+_156807663 0.93 ENST00000467995.1
ENST00000474477.1
ENST00000471719.1
LINC00881
long intergenic non-protein coding RNA 881
chr7_-_91509972 0.69 ENST00000425936.1
MTERF
mitochondrial transcription termination factor
chr2_-_36779411 0.65 ENST00000406220.1
AC007401.2
Uncharacterized protein
chr22_-_38480100 0.60 ENST00000427592.1
SLC16A8
solute carrier family 16 (monocarboxylate transporter), member 8
chr11_+_65265141 0.58 ENST00000534336.1
MALAT1
metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
chr3_+_171561127 0.54 ENST00000334567.5
ENST00000450693.1
TMEM212
transmembrane protein 212
chr13_-_30951282 0.53 ENST00000420219.1
LINC00426
long intergenic non-protein coding RNA 426
chr2_-_112237835 0.51 ENST00000442293.1
ENST00000439494.1
MIR4435-1HG
MIR4435-1 host gene (non-protein coding)
chr21_+_38888740 0.48 ENST00000597817.1
AP001421.1
Uncharacterized protein
chr19_+_52076425 0.47 ENST00000436511.2
ZNF175
zinc finger protein 175
chr19_-_43835582 0.42 ENST00000595748.1
CTC-490G23.2
CTC-490G23.2
chr17_-_57229155 0.42 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr14_-_30766223 0.42 ENST00000549360.1
ENST00000508469.2
CTD-2251F13.1
CTD-2251F13.1
chr1_-_31902614 0.42 ENST00000596131.1
AC114494.1
HCG1787699; Uncharacterized protein
chr11_+_59705928 0.34 ENST00000398992.1
OOSP1
oocyte secreted protein 1
chr7_-_37382360 0.34 ENST00000455119.1
ELMO1
engulfment and cell motility 1
chr14_+_52164675 0.34 ENST00000555936.1
FRMD6
FERM domain containing 6
chr3_-_42003613 0.33 ENST00000414606.1
ULK4
unc-51 like kinase 4
chr7_+_141463897 0.32 ENST00000247879.2
TAS2R3
taste receptor, type 2, member 3
chr4_+_70916119 0.31 ENST00000246896.3
ENST00000511674.1
HTN1
histatin 1
chr1_-_146989697 0.30 ENST00000437831.1
LINC00624
long intergenic non-protein coding RNA 624
chr4_-_14889791 0.30 ENST00000509654.1
ENST00000515031.1
ENST00000505089.2
LINC00504
long intergenic non-protein coding RNA 504
chr14_+_65182395 0.30 ENST00000554088.1
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr13_+_110958124 0.29 ENST00000400163.2
COL4A2
collagen, type IV, alpha 2
chr11_-_104480019 0.29 ENST00000536529.1
ENST00000545630.1
ENST00000538641.1
RP11-886D15.1
RP11-886D15.1
chr6_-_32977345 0.28 ENST00000450833.2
ENST00000374813.1
ENST00000229829.5
HLA-DOA
major histocompatibility complex, class II, DO alpha
chr7_-_46736720 0.28 ENST00000451905.1
AC011294.3
Uncharacterized protein
chr1_-_17231271 0.26 ENST00000606899.1
RP11-108M9.6
RP11-108M9.6
chr12_-_15103621 0.25 ENST00000536592.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr3_+_42544084 0.25 ENST00000543411.1
ENST00000438259.2
ENST00000439731.1
ENST00000325123.4
VIPR1
vasoactive intestinal peptide receptor 1
chr17_-_7216939 0.23 ENST00000573684.1
GPS2
G protein pathway suppressor 2
chr22_-_37882395 0.22 ENST00000416983.3
ENST00000424765.2
ENST00000356998.3
MFNG
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr3_-_120365866 0.22 ENST00000475447.2
HGD
homogentisate 1,2-dioxygenase
chr15_+_84841242 0.22 ENST00000558195.1
RP11-182J1.16
ubiquitin-conjugating enzyme E2Q family member 2-like
chr17_-_29624343 0.21 ENST00000247271.4
OMG
oligodendrocyte myelin glycoprotein
chr14_+_50779029 0.21 ENST00000245448.6
ATP5S
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
chr3_-_42003479 0.21 ENST00000420927.1
ULK4
unc-51 like kinase 4
chr14_+_64680854 0.20 ENST00000458046.2
SYNE2
spectrin repeat containing, nuclear envelope 2
chr17_+_38334501 0.20 ENST00000541245.1
RAPGEFL1
Rap guanine nucleotide exchange factor (GEF)-like 1
chr1_-_198906528 0.19 ENST00000432296.1
MIR181A1HG
MIR181A1 host gene (non-protein coding)
chr2_+_87769459 0.19 ENST00000414030.1
ENST00000437561.1
LINC00152
long intergenic non-protein coding RNA 152
chr10_+_38717074 0.19 ENST00000423687.1
LINC00999
long intergenic non-protein coding RNA 999
chr12_-_86230315 0.18 ENST00000361228.3
RASSF9
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
chr19_-_51611623 0.17 ENST00000421832.2
CTU1
cytosolic thiouridylase subunit 1
chr11_-_64527425 0.17 ENST00000377432.3
PYGM
phosphorylase, glycogen, muscle
chr2_-_69870835 0.17 ENST00000409085.4
ENST00000406297.3
AAK1
AP2 associated kinase 1
chr17_+_44370099 0.17 ENST00000496930.1
LRRC37A
leucine rich repeat containing 37A
chr19_-_49843539 0.17 ENST00000602554.1
ENST00000358234.4
CTC-301O7.4
CTC-301O7.4
chr9_-_215744 0.16 ENST00000382387.2
C9orf66
chromosome 9 open reading frame 66
chr5_+_173763250 0.16 ENST00000515513.1
ENST00000507361.1
ENST00000510234.1
RP11-267A15.1
RP11-267A15.1
chr2_-_69870747 0.16 ENST00000409068.1
AAK1
AP2 associated kinase 1
chr12_+_14561422 0.16 ENST00000541056.1
ATF7IP
activating transcription factor 7 interacting protein
chr2_+_70142189 0.16 ENST00000264444.2
MXD1
MAX dimerization protein 1
chr9_+_35906176 0.15 ENST00000354323.2
HRCT1
histidine rich carboxyl terminus 1
chr11_-_66360548 0.15 ENST00000333861.3
CCDC87
coiled-coil domain containing 87
chr10_-_105437909 0.15 ENST00000540321.1
SH3PXD2A
SH3 and PX domains 2A
chr10_-_91403625 0.15 ENST00000322191.6
ENST00000342512.3
ENST00000371774.2
PANK1
pantothenate kinase 1
chr1_+_1243947 0.15 ENST00000379031.5
PUSL1
pseudouridylate synthase-like 1
chr17_-_47723943 0.15 ENST00000510476.1
ENST00000503676.1
SPOP
speckle-type POZ protein
chr8_+_42396712 0.14 ENST00000518574.1
ENST00000417410.2
ENST00000414154.2
SMIM19
small integral membrane protein 19
chr16_-_69373396 0.14 ENST00000562595.1
ENST00000562081.1
ENST00000306875.4
COG8
component of oligomeric golgi complex 8
chr11_+_65627974 0.14 ENST00000525768.1
MUS81
MUS81 structure-specific endonuclease subunit
chr12_+_120031264 0.14 ENST00000426426.1
TMEM233
transmembrane protein 233
chr19_-_49552363 0.14 ENST00000448456.3
ENST00000355414.2
CGB8
chorionic gonadotropin, beta polypeptide 8
chr1_-_227505289 0.13 ENST00000366765.3
CDC42BPA
CDC42 binding protein kinase alpha (DMPK-like)
chr16_+_58783542 0.13 ENST00000500117.1
ENST00000565722.1
RP11-410D17.2
RP11-410D17.2
chr1_-_21377383 0.13 ENST00000374935.3
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr8_+_99076750 0.13 ENST00000545282.1
C8orf47
chromosome 8 open reading frame 47
chr19_+_3178736 0.13 ENST00000246115.3
S1PR4
sphingosine-1-phosphate receptor 4
chr17_-_6524159 0.13 ENST00000589033.1
KIAA0753
KIAA0753
chr15_-_55563072 0.13 ENST00000567380.1
ENST00000565972.1
ENST00000569493.1
RAB27A
RAB27A, member RAS oncogene family
chr8_+_99076509 0.12 ENST00000318528.3
C8orf47
chromosome 8 open reading frame 47
chr22_+_23229960 0.12 ENST00000526893.1
ENST00000532223.2
ENST00000531372.1
IGLL5
immunoglobulin lambda-like polypeptide 5
chr13_-_26452679 0.12 ENST00000596729.1
AL138815.2
Uncharacterized protein
chr1_+_171217622 0.12 ENST00000433267.1
ENST00000367750.3
FMO1
flavin containing monooxygenase 1
chr2_+_102927962 0.11 ENST00000233954.1
ENST00000393393.3
ENST00000410040.1
IL1RL1
IL18R1
interleukin 1 receptor-like 1
interleukin 18 receptor 1
chr1_-_108231101 0.11 ENST00000544443.1
ENST00000415432.2
VAV3
vav 3 guanine nucleotide exchange factor
chrX_-_47341928 0.11 ENST00000313116.7
ZNF41
zinc finger protein 41
chr19_-_6459746 0.11 ENST00000301454.4
ENST00000334510.5
SLC25A23
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
chr7_-_56101826 0.11 ENST00000421626.1
PSPH
phosphoserine phosphatase
chr5_-_59481406 0.11 ENST00000546160.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr3_-_123339418 0.11 ENST00000583087.1
MYLK
myosin light chain kinase
chr18_+_39535239 0.11 ENST00000585528.1
PIK3C3
phosphatidylinositol 3-kinase, catalytic subunit type 3
chr1_-_21377447 0.10 ENST00000374937.3
ENST00000264211.8
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr11_-_129817356 0.10 ENST00000526082.1
PRDM10
PR domain containing 10
chr15_-_41120896 0.10 ENST00000299174.5
ENST00000427255.2
PPP1R14D
protein phosphatase 1, regulatory (inhibitor) subunit 14D
chr10_+_32735030 0.10 ENST00000277657.6
ENST00000362006.5
CCDC7
coiled-coil domain containing 7
chr4_+_113739244 0.10 ENST00000503271.1
ENST00000503423.1
ENST00000506722.1
ANK2
ankyrin 2, neuronal
chr7_+_100466433 0.10 ENST00000429658.1
TRIP6
thyroid hormone receptor interactor 6
chr12_+_32259696 0.10 ENST00000551848.1
BICD1
bicaudal D homolog 1 (Drosophila)
chr14_-_31856397 0.09 ENST00000538864.2
ENST00000550366.1
HEATR5A
HEAT repeat containing 5A
chr1_+_202431859 0.09 ENST00000391959.3
ENST00000367270.4
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr2_-_27545921 0.09 ENST00000402310.1
ENST00000405983.1
ENST00000403262.2
ENST00000428910.1
ENST00000402722.1
ENST00000399052.4
ENST00000380044.1
ENST00000405076.1
MPV17
MpV17 mitochondrial inner membrane protein
chr10_+_115939008 0.09 ENST00000369282.1
ENST00000251864.2
ENST00000369281.2
ENST00000422662.1
TDRD1
tudor domain containing 1
chr2_+_203776937 0.09 ENST00000402905.3
ENST00000414490.1
ENST00000431787.1
ENST00000444724.1
ENST00000414857.1
ENST00000430899.1
ENST00000445120.1
ENST00000441569.1
ENST00000432024.1
ENST00000443740.1
ENST00000414439.1
ENST00000428585.1
ENST00000545253.1
ENST00000545262.1
ENST00000447539.1
ENST00000456821.2
ENST00000434998.1
ENST00000320443.8
CARF
calcium responsive transcription factor
chr8_+_20054878 0.09 ENST00000276390.2
ENST00000519667.1
ATP6V1B2
ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
chr17_+_33914460 0.09 ENST00000537622.2
AP2B1
adaptor-related protein complex 2, beta 1 subunit
chr12_-_56236690 0.09 ENST00000322569.4
MMP19
matrix metallopeptidase 19
chr19_-_12708113 0.09 ENST00000440366.1
ZNF490
zinc finger protein 490
chr19_-_49552006 0.09 ENST00000391869.3
CGB1
chorionic gonadotropin, beta polypeptide 1
chr14_+_52164820 0.09 ENST00000554167.1
FRMD6
FERM domain containing 6
chr12_+_56075330 0.09 ENST00000394252.3
METTL7B
methyltransferase like 7B
chr9_+_96846740 0.09 ENST00000288976.3
PTPDC1
protein tyrosine phosphatase domain containing 1
chr15_-_65579177 0.09 ENST00000444347.2
ENST00000261888.6
PARP16
poly (ADP-ribose) polymerase family, member 16
chr19_-_56110859 0.09 ENST00000221665.3
ENST00000592585.1
FIZ1
FLT3-interacting zinc finger 1
chr7_-_150777920 0.08 ENST00000353841.2
ENST00000297532.6
FASTK
Fas-activated serine/threonine kinase
chr1_+_159796589 0.08 ENST00000368104.4
SLAMF8
SLAM family member 8
chr19_-_37663572 0.08 ENST00000588354.1
ENST00000292841.5
ENST00000355533.2
ENST00000356958.4
ZNF585A
zinc finger protein 585A
chr17_+_33914276 0.08 ENST00000592545.1
ENST00000538556.1
ENST00000312678.8
ENST00000589344.1
AP2B1
adaptor-related protein complex 2, beta 1 subunit
chr5_-_9903938 0.08 ENST00000511616.1
CTD-2143L24.1
CTD-2143L24.1
chr6_+_109169591 0.08 ENST00000368972.3
ENST00000392644.4
ARMC2
armadillo repeat containing 2
chr17_-_62493131 0.08 ENST00000539111.2
POLG2
polymerase (DNA directed), gamma 2, accessory subunit
chr1_+_205225319 0.08 ENST00000329800.7
TMCC2
transmembrane and coiled-coil domain family 2
chr9_-_70465758 0.08 ENST00000489273.1
CBWD5
COBW domain containing 5
chr14_+_50779071 0.08 ENST00000426751.2
ATP5S
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
chr6_-_15586238 0.08 ENST00000462989.2
DTNBP1
dystrobrevin binding protein 1
chr2_-_121624973 0.08 ENST00000603720.1
RP11-297J22.1
RP11-297J22.1
chr9_+_116263639 0.08 ENST00000343817.5
RGS3
regulator of G-protein signaling 3
chr4_-_186317034 0.08 ENST00000505916.1
LRP2BP
LRP2 binding protein
chr10_-_4720301 0.08 ENST00000449712.1
LINC00704
long intergenic non-protein coding RNA 704
chr3_+_132316081 0.07 ENST00000249887.2
ACKR4
atypical chemokine receptor 4
chr11_-_64684672 0.07 ENST00000377264.3
ENST00000421419.2
ATG2A
autophagy related 2A
chr9_-_4859260 0.07 ENST00000599351.1
AL158147.2
HCG2011465; Uncharacterized protein
chr6_+_155443048 0.07 ENST00000535583.1
TIAM2
T-cell lymphoma invasion and metastasis 2
chr8_+_42396936 0.07 ENST00000416469.2
SMIM19
small integral membrane protein 19
chr1_-_115259337 0.07 ENST00000369535.4
NRAS
neuroblastoma RAS viral (v-ras) oncogene homolog
chr4_-_175041663 0.07 ENST00000503140.1
RP11-148L24.1
RP11-148L24.1
chr17_+_34890807 0.07 ENST00000429467.2
ENST00000592983.1
PIGW
phosphatidylinositol glycan anchor biosynthesis, class W
chr19_+_42746927 0.07 ENST00000378108.1
AC006486.1
AC006486.1
chr8_+_136469684 0.07 ENST00000355849.5
KHDRBS3
KH domain containing, RNA binding, signal transduction associated 3
chr19_+_52074502 0.06 ENST00000545217.1
ENST00000262259.2
ENST00000596504.1
ZNF175
zinc finger protein 175
chr2_+_70142232 0.06 ENST00000540449.1
MXD1
MAX dimerization protein 1
chr3_-_113956425 0.06 ENST00000482457.2
ZNF80
zinc finger protein 80
chr13_+_27998681 0.06 ENST00000381140.4
GTF3A
general transcription factor IIIA
chr4_-_170924888 0.06 ENST00000502832.1
ENST00000393704.3
MFAP3L
microfibrillar-associated protein 3-like
chr12_-_76377795 0.06 ENST00000552856.1
RP11-114H23.1
RP11-114H23.1
chr7_-_6865826 0.06 ENST00000538180.1
CCZ1B
CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
chr11_+_64685026 0.06 ENST00000526559.1
PPP2R5B
protein phosphatase 2, regulatory subunit B', beta
chr1_+_110162448 0.06 ENST00000342115.4
ENST00000469039.2
ENST00000474459.1
ENST00000528667.1
AMPD2
adenosine monophosphate deaminase 2
chr5_+_74907284 0.06 ENST00000601380.2
ANKDD1B
ankyrin repeat and death domain containing 1B
chr3_-_39196049 0.06 ENST00000514182.1
CSRNP1
cysteine-serine-rich nuclear protein 1
chr7_+_121513143 0.06 ENST00000393386.2
PTPRZ1
protein tyrosine phosphatase, receptor-type, Z polypeptide 1
chr1_+_113009163 0.06 ENST00000256640.5
WNT2B
wingless-type MMTV integration site family, member 2B
chr14_+_91709103 0.06 ENST00000553725.1
CTD-2547L24.3
HCG1816139; Uncharacterized protein
chr8_-_95220775 0.05 ENST00000441892.2
ENST00000521491.1
ENST00000027335.3
CDH17
cadherin 17, LI cadherin (liver-intestine)
chr11_-_61687739 0.05 ENST00000531922.1
ENST00000301773.5
RAB3IL1
RAB3A interacting protein (rabin3)-like 1
chr19_+_56111680 0.05 ENST00000301073.3
ZNF524
zinc finger protein 524
chr3_+_100428316 0.05 ENST00000479672.1
ENST00000476228.1
ENST00000463568.1
TFG
TRK-fused gene
chr19_+_17186577 0.05 ENST00000595618.1
ENST00000594824.1
MYO9B
myosin IXB
chr11_-_8816375 0.05 ENST00000530580.1
ST5
suppression of tumorigenicity 5
chr11_+_27062860 0.05 ENST00000528583.1
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr7_+_128116783 0.05 ENST00000262432.8
ENST00000480046.1
METTL2B
methyltransferase like 2B
chr17_+_41150793 0.05 ENST00000586277.1
RPL27
ribosomal protein L27
chr4_+_186317133 0.05 ENST00000507753.1
ANKRD37
ankyrin repeat domain 37
chr11_-_129817448 0.05 ENST00000304538.6
PRDM10
PR domain containing 10
chr3_+_37035289 0.05 ENST00000455445.2
ENST00000441265.1
ENST00000435176.1
ENST00000429117.1
ENST00000536378.1
MLH1
mutL homolog 1
chr1_-_31538517 0.05 ENST00000440538.2
ENST00000423018.2
ENST00000424085.2
ENST00000426105.2
ENST00000257075.5
ENST00000373747.3
ENST00000525843.1
ENST00000373742.2
PUM1
pumilio RNA-binding family member 1
chr11_-_6640585 0.05 ENST00000533371.1
ENST00000528657.1
ENST00000436873.2
ENST00000299427.6
TPP1
tripeptidyl peptidase I
chr7_-_150777949 0.05 ENST00000482571.1
FASTK
Fas-activated serine/threonine kinase
chr5_+_140071011 0.05 ENST00000230771.3
ENST00000509299.1
ENST00000503873.1
ENST00000435019.2
ENST00000437649.2
ENST00000432671.2
HARS2
histidyl-tRNA synthetase 2, mitochondrial
chr6_-_80247105 0.05 ENST00000369846.4
LCA5
Leber congenital amaurosis 5
chr12_+_44152740 0.05 ENST00000440781.2
ENST00000431837.1
ENST00000550616.1
ENST00000448290.2
ENST00000551736.1
IRAK4
interleukin-1 receptor-associated kinase 4
chr2_-_202298268 0.05 ENST00000440597.1
TRAK2
trafficking protein, kinesin binding 2
chr14_-_60337684 0.05 ENST00000267484.5
RTN1
reticulon 1
chr6_+_42584847 0.04 ENST00000372883.3
UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr15_+_65843130 0.04 ENST00000569894.1
PTPLAD1
protein tyrosine phosphatase-like A domain containing 1
chr18_-_10791648 0.04 ENST00000583325.1
PIEZO2
piezo-type mechanosensitive ion channel component 2
chr12_+_70219052 0.04 ENST00000552032.2
ENST00000547771.2
MYRFL
myelin regulatory factor-like
chr19_+_58144529 0.04 ENST00000347302.3
ENST00000254182.7
ENST00000391703.3
ENST00000541801.1
ENST00000299871.5
ENST00000544273.1
ZNF211
zinc finger protein 211
chr11_+_118754475 0.04 ENST00000292174.4
CXCR5
chemokine (C-X-C motif) receptor 5
chr17_+_66521936 0.04 ENST00000592800.1
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr5_+_140723601 0.04 ENST00000253812.6
PCDHGA3
protocadherin gamma subfamily A, 3
chr20_-_36661826 0.04 ENST00000373448.2
ENST00000373447.3
TTI1
TELO2 interacting protein 1
chr21_-_43735628 0.04 ENST00000291525.10
ENST00000518498.1
TFF3
trefoil factor 3 (intestinal)
chr10_+_135204338 0.04 ENST00000468317.2
RP11-108K14.8
Mitochondrial GTPase 1
chr9_+_127023704 0.04 ENST00000373596.1
ENST00000425237.1
NEK6
NIMA-related kinase 6
chr12_-_57039739 0.03 ENST00000552959.1
ENST00000551020.1
ENST00000553007.2
ENST00000552919.1
ENST00000552104.1
ENST00000262030.3
ATP5B
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
chr7_+_5938386 0.03 ENST00000537980.1
CCZ1
CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
chr11_+_27062502 0.03 ENST00000263182.3
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr19_-_37663332 0.03 ENST00000392157.2
ZNF585A
zinc finger protein 585A
chr11_+_65627865 0.03 ENST00000308110.4
MUS81
MUS81 structure-specific endonuclease subunit
chr2_-_100721923 0.03 ENST00000356421.2
AFF3
AF4/FMR2 family, member 3
chr1_+_110163202 0.03 ENST00000531203.1
ENST00000256578.3
AMPD2
adenosine monophosphate deaminase 2
chr10_-_27529486 0.03 ENST00000375888.1
ACBD5
acyl-CoA binding domain containing 5
chr2_+_109335929 0.03 ENST00000283195.6
RANBP2
RAN binding protein 2
chr3_+_186435065 0.03 ENST00000287611.2
ENST00000265023.4
KNG1
kininogen 1
chr4_-_48082192 0.03 ENST00000507351.1
TXK
TXK tyrosine kinase
chr4_-_1685718 0.03 ENST00000472884.2
ENST00000489363.1
ENST00000308132.6
ENST00000463238.1
FAM53A
family with sequence similarity 53, member A
chr17_-_44896047 0.03 ENST00000225512.5
WNT3
wingless-type MMTV integration site family, member 3
chr1_+_19578033 0.03 ENST00000330263.4
MRTO4
mRNA turnover 4 homolog (S. cerevisiae)
chr5_-_177210399 0.03 ENST00000510276.1
FAM153A
family with sequence similarity 153, member A
chr9_+_97766469 0.03 ENST00000433691.2
C9orf3
chromosome 9 open reading frame 3
chr14_+_100531615 0.03 ENST00000392920.3
EVL
Enah/Vasp-like
chr15_+_43425672 0.03 ENST00000260403.2
TMEM62
transmembrane protein 62
chr3_-_15106747 0.02 ENST00000449354.2
ENST00000444840.2
ENST00000253686.2
MRPS25
mitochondrial ribosomal protein S25
chrX_-_128782722 0.02 ENST00000427399.1
APLN
apelin
chr11_+_27062272 0.02 ENST00000529202.1
ENST00000533566.1
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr9_+_134065506 0.02 ENST00000483497.2
NUP214
nucleoporin 214kDa
chr3_-_46249878 0.02 ENST00000296140.3
CCR1
chemokine (C-C motif) receptor 1

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX2-6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586)
0.0 0.4 GO:0003383 apical constriction(GO:0003383)
0.0 0.6 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 0.3 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.2 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.0 0.1 GO:1900276 regulation of proteinase activated receptor activity(GO:1900276) negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900737)
0.0 0.2 GO:0034227 tRNA thio-modification(GO:0034227)
0.0 0.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.2 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.1 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.1 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.1 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.2 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.1 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.3 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.0 GO:0098972 dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
0.0 0.5 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.0 0.1 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.1 GO:0035865 cellular response to potassium ion(GO:0035865)
0.0 0.1 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.0 0.3 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.1 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.1 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.3 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.1 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.3 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.1 GO:0001554 luteolysis(GO:0001554)
0.0 0.0 GO:0060061 Spemann organizer formation(GO:0060061)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.1 GO:0039714 viral factory(GO:0039713) cytoplasmic viral factory(GO:0039714) host cell viral assembly compartment(GO:0072517)
0.0 0.2 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.1 GO:0000229 cytoplasmic chromosome(GO:0000229)
0.0 0.1 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.3 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.0 GO:0072534 perineuronal net(GO:0072534)
0.0 0.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.0 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.0 0.1 GO:0071546 pi-body(GO:0071546)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0048257 3'-flap endonuclease activity(GO:0048257)
0.0 0.2 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.6 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.2 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.2 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.0 0.1 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.0 0.1 GO:0002113 interleukin-33 binding(GO:0002113)
0.0 0.1 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.3 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.3 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.1 GO:0005427 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
0.0 0.1 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters