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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for NHLH1

Z-value: 1.05

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Transcription factors associated with NHLH1

Gene Symbol Gene ID Gene Info
NHLH1
ENSG00000171786.5 nescient helix-loop-helix 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NHLH1hg19_v2_chr1_+_160336851_1603368680.796.4e-02Click!

Activity profile of NHLH1 motif

Sorted Z-values of NHLH1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr22_-_21905120 1.39 ENST00000331505.5
RIMBP3C
RIMS binding protein 3C
chr4_+_89299994 0.71 ENST00000264346.7
HERC6
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr4_+_89299885 0.66 ENST00000380265.5
ENST00000273960.3
HERC6
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr2_-_7005785 0.65 ENST00000256722.5
ENST00000404168.1
ENST00000458098.1
CMPK2
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr17_-_39316983 0.63 ENST00000390661.3
KRTAP4-4
keratin associated protein 4-4
chr1_-_47134085 0.48 ENST00000371937.4
ENST00000574428.1
ENST00000329231.4
ATPAF1
ATP synthase mitochondrial F1 complex assembly factor 1
chr6_+_26156551 0.47 ENST00000304218.3
HIST1H1E
histone cluster 1, H1e
chr20_-_62493217 0.42 ENST00000601296.1
C20ORF135
C20ORF135
chr1_-_197744763 0.38 ENST00000422998.1
DENND1B
DENN/MADD domain containing 1B
chr11_-_1606513 0.38 ENST00000382171.2
KRTAP5-1
keratin associated protein 5-1
chr11_-_64764435 0.38 ENST00000534177.1
ENST00000301887.4
BATF2
basic leucine zipper transcription factor, ATF-like 2
chr6_+_31895467 0.37 ENST00000556679.1
ENST00000456570.1
CFB
CFB
complement factor B
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr1_-_47134101 0.36 ENST00000576409.1
ATPAF1
ATP synthase mitochondrial F1 complex assembly factor 1
chr6_+_126112001 0.34 ENST00000392477.2
NCOA7
nuclear receptor coactivator 7
chr3_-_133614297 0.33 ENST00000486858.1
ENST00000477759.1
RAB6B
RAB6B, member RAS oncogene family
chr1_+_206809113 0.33 ENST00000441486.1
ENST00000367106.1
DYRK3
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
chr17_-_54991369 0.32 ENST00000537230.1
TRIM25
tripartite motif containing 25
chr12_+_652294 0.31 ENST00000322843.3
B4GALNT3
beta-1,4-N-acetyl-galactosaminyl transferase 3
chr4_+_86749045 0.31 ENST00000514229.1
ARHGAP24
Rho GTPase activating protein 24
chr7_+_72848092 0.31 ENST00000344575.3
FZD9
frizzled family receptor 9
chr20_+_30193083 0.30 ENST00000376112.3
ENST00000376105.3
ID1
inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
chr12_-_74686314 0.30 ENST00000551210.1
ENST00000515416.2
ENST00000549905.1
RP11-81H3.2
RP11-81H3.2
chr1_+_28918712 0.28 ENST00000373826.3
RAB42
RAB42, member RAS oncogene family
chr1_+_161185032 0.27 ENST00000367992.3
ENST00000289902.1
FCER1G
Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
chr17_-_54991395 0.27 ENST00000316881.4
TRIM25
tripartite motif containing 25
chr6_+_31895480 0.26 ENST00000418949.2
ENST00000383177.3
ENST00000477310.1
C2
CFB
complement component 2
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr4_-_41216492 0.26 ENST00000503503.1
ENST00000509446.1
ENST00000503264.1
ENST00000508707.1
ENST00000508593.1
APBB2
amyloid beta (A4) precursor protein-binding, family B, member 2
chr4_-_41216619 0.26 ENST00000508676.1
ENST00000506352.1
ENST00000295974.8
APBB2
amyloid beta (A4) precursor protein-binding, family B, member 2
chr2_-_96811170 0.25 ENST00000288943.4
DUSP2
dual specificity phosphatase 2
chr19_-_12889226 0.25 ENST00000589400.1
ENST00000590839.1
ENST00000592079.1
HOOK2
hook microtubule-tethering protein 2
chr17_-_31620006 0.25 ENST00000225823.2
ASIC2
acid-sensing (proton-gated) ion channel 2
chr6_-_134861089 0.24 ENST00000606039.1
RP11-557H15.4
RP11-557H15.4
chr16_+_68771128 0.24 ENST00000261769.5
ENST00000422392.2
CDH1
cadherin 1, type 1, E-cadherin (epithelial)
chr19_+_17858547 0.24 ENST00000600676.1
ENST00000600209.1
ENST00000596309.1
ENST00000598539.1
ENST00000597474.1
ENST00000593385.1
ENST00000598067.1
ENST00000593833.1
FCHO1
FCH domain only 1
chr5_+_148737562 0.23 ENST00000274569.4
PCYOX1L
prenylcysteine oxidase 1 like
chrX_+_49126294 0.23 ENST00000466508.1
ENST00000438316.1
ENST00000055335.6
ENST00000495799.1
PPP1R3F
protein phosphatase 1, regulatory subunit 3F
chr6_+_126112074 0.23 ENST00000453302.1
ENST00000417494.1
ENST00000229634.9
NCOA7
nuclear receptor coactivator 7
chr1_-_92351666 0.22 ENST00000465892.2
ENST00000417833.2
TGFBR3
transforming growth factor, beta receptor III
chr7_-_100808843 0.22 ENST00000249330.2
VGF
VGF nerve growth factor inducible
chr5_-_1882858 0.22 ENST00000511126.1
ENST00000231357.2
IRX4
iroquois homeobox 4
chr17_+_39411636 0.22 ENST00000394008.1
KRTAP9-9
keratin associated protein 9-9
chr16_+_23847355 0.21 ENST00000498058.1
PRKCB
protein kinase C, beta
chr3_-_133614597 0.21 ENST00000285208.4
ENST00000460865.3
RAB6B
RAB6B, member RAS oncogene family
chr2_+_105471969 0.21 ENST00000361360.2
POU3F3
POU class 3 homeobox 3
chr16_+_19222479 0.21 ENST00000568433.1
SYT17
synaptotagmin XVII
chr12_-_6715808 0.21 ENST00000545584.1
CHD4
chromodomain helicase DNA binding protein 4
chr3_-_133614421 0.20 ENST00000543906.1
RAB6B
RAB6B, member RAS oncogene family
chr1_+_33352036 0.20 ENST00000373467.3
HPCA
hippocalcin
chr20_-_14318248 0.20 ENST00000378053.3
ENST00000341420.4
FLRT3
fibronectin leucine rich transmembrane protein 3
chr1_-_53387352 0.20 ENST00000541281.1
ECHDC2
enoyl CoA hydratase domain containing 2
chr4_+_75310851 0.20 ENST00000395748.3
ENST00000264487.2
AREG
amphiregulin
chr22_-_50964849 0.20 ENST00000543927.1
ENST00000423348.1
SCO2
SCO2 cytochrome c oxidase assembly protein
chr5_-_138739739 0.20 ENST00000514983.1
ENST00000507779.2
ENST00000451821.2
ENST00000450845.2
ENST00000509959.1
ENST00000302091.5
SPATA24
spermatogenesis associated 24
chr2_+_33359473 0.20 ENST00000432635.1
LTBP1
latent transforming growth factor beta binding protein 1
chr6_+_44095263 0.20 ENST00000532634.1
TMEM63B
transmembrane protein 63B
chr6_+_13615554 0.19 ENST00000451315.2
NOL7
nucleolar protein 7, 27kDa
chr4_+_75311019 0.19 ENST00000502307.1
AREG
amphiregulin
chr19_-_17366257 0.19 ENST00000594059.1
AC010646.3
Uncharacterized protein
chr16_+_23847267 0.19 ENST00000321728.7
PRKCB
protein kinase C, beta
chr17_+_80193644 0.19 ENST00000582946.1
SLC16A3
solute carrier family 16 (monocarboxylate transporter), member 3
chr1_+_32538492 0.19 ENST00000336294.5
TMEM39B
transmembrane protein 39B
chr12_+_122064673 0.18 ENST00000537188.1
ORAI1
ORAI calcium release-activated calcium modulator 1
chr2_-_19558373 0.18 ENST00000272223.2
OSR1
odd-skipped related transciption factor 1
chr14_-_24551195 0.18 ENST00000560550.1
NRL
neural retina leucine zipper
chr5_+_49962772 0.18 ENST00000281631.5
ENST00000513738.1
ENST00000503665.1
ENST00000514067.2
ENST00000503046.1
PARP8
poly (ADP-ribose) polymerase family, member 8
chr17_+_26369865 0.18 ENST00000582037.1
NLK
nemo-like kinase
chr1_+_206808918 0.18 ENST00000367108.3
DYRK3
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
chr3_-_45187843 0.18 ENST00000296129.1
ENST00000425231.2
CDCP1
CUB domain containing protein 1
chr7_-_73184588 0.18 ENST00000395145.2
CLDN3
claudin 3
chr5_+_118788182 0.17 ENST00000515320.1
ENST00000510025.1
HSD17B4
hydroxysteroid (17-beta) dehydrogenase 4
chr9_-_4679419 0.17 ENST00000609131.1
ENST00000607997.1
RP11-6J24.6
RP11-6J24.6
chrX_+_107068959 0.17 ENST00000451923.1
MID2
midline 2
chr17_-_27278304 0.17 ENST00000577226.1
PHF12
PHD finger protein 12
chr1_+_206808868 0.17 ENST00000367109.2
DYRK3
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
chr12_-_67197760 0.17 ENST00000539540.1
ENST00000540433.1
ENST00000541947.1
ENST00000538373.1
GRIP1
glutamate receptor interacting protein 1
chr11_-_67188642 0.17 ENST00000546202.1
ENST00000542876.1
PPP1CA
protein phosphatase 1, catalytic subunit, alpha isozyme
chr12_-_67072714 0.17 ENST00000545666.1
ENST00000398016.3
ENST00000359742.4
ENST00000286445.7
ENST00000538211.1
GRIP1
glutamate receptor interacting protein 1
chr14_+_31343951 0.17 ENST00000556908.1
ENST00000555881.1
ENST00000460581.2
COCH
cochlin
chr4_+_3768075 0.16 ENST00000509482.1
ENST00000330055.5
ADRA2C
adrenoceptor alpha 2C
chr6_-_30712313 0.16 ENST00000376377.2
ENST00000259874.5
IER3
immediate early response 3
chr14_+_24584056 0.16 ENST00000561001.1
DCAF11
DDB1 and CUL4 associated factor 11
chr11_-_63684316 0.16 ENST00000301459.4
RCOR2
REST corepressor 2
chr1_-_3713042 0.16 ENST00000378251.1
LRRC47
leucine rich repeat containing 47
chr12_-_6579808 0.16 ENST00000535180.1
ENST00000400911.3
VAMP1
vesicle-associated membrane protein 1 (synaptobrevin 1)
chr11_+_61276214 0.16 ENST00000378075.2
LRRC10B
leucine rich repeat containing 10B
chr5_+_118788261 0.16 ENST00000504811.1
HSD17B4
hydroxysteroid (17-beta) dehydrogenase 4
chr17_+_48638371 0.16 ENST00000360761.4
ENST00000352832.5
ENST00000354983.4
CACNA1G
calcium channel, voltage-dependent, T type, alpha 1G subunit
chr5_+_176237478 0.16 ENST00000329542.4
UNC5A
unc-5 homolog A (C. elegans)
chr4_-_80994210 0.16 ENST00000403729.2
ANTXR2
anthrax toxin receptor 2
chr12_+_107168418 0.16 ENST00000392839.2
ENST00000548914.1
ENST00000355478.2
ENST00000552619.1
ENST00000549643.1
RIC8B
RIC8 guanine nucleotide exchange factor B
chr14_+_62162258 0.16 ENST00000337138.4
ENST00000394997.1
HIF1A
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
chr12_-_31743901 0.15 ENST00000354285.4
DENND5B
DENN/MADD domain containing 5B
chrX_-_57163430 0.15 ENST00000374908.1
SPIN2A
spindlin family, member 2A
chr12_-_113658892 0.15 ENST00000299732.2
ENST00000416617.2
IQCD
IQ motif containing D
chr3_-_87039662 0.15 ENST00000494229.1
VGLL3
vestigial like 3 (Drosophila)
chr19_+_35521572 0.15 ENST00000262631.5
SCN1B
sodium channel, voltage-gated, type I, beta subunit
chr12_+_56137064 0.15 ENST00000257868.5
ENST00000546799.1
GDF11
growth differentiation factor 11
chr12_+_7055767 0.15 ENST00000447931.2
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr16_-_88772761 0.15 ENST00000567844.1
ENST00000312838.4
RNF166
ring finger protein 166
chr2_-_230135937 0.15 ENST00000392054.3
ENST00000409462.1
ENST00000392055.3
PID1
phosphotyrosine interaction domain containing 1
chr19_+_13228917 0.15 ENST00000586171.1
NACC1
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr22_-_50964558 0.15 ENST00000535425.1
ENST00000439934.1
SCO2
SCO2 cytochrome c oxidase assembly protein
chr16_+_69345243 0.15 ENST00000254950.11
VPS4A
vacuolar protein sorting 4 homolog A (S. cerevisiae)
chr5_-_138730817 0.14 ENST00000434752.2
PROB1
proline-rich basic protein 1
chr9_+_125703282 0.14 ENST00000373647.4
ENST00000402311.1
RABGAP1
RAB GTPase activating protein 1
chr19_+_48876300 0.14 ENST00000600863.1
ENST00000601610.1
ENST00000595322.1
SYNGR4
synaptogyrin 4
chr8_+_128748308 0.14 ENST00000377970.2
MYC
v-myc avian myelocytomatosis viral oncogene homolog
chr5_+_102201687 0.14 ENST00000304400.7
PAM
peptidylglycine alpha-amidating monooxygenase
chr8_-_125740514 0.14 ENST00000325064.5
ENST00000518547.1
MTSS1
metastasis suppressor 1
chr7_-_84816122 0.14 ENST00000444867.1
SEMA3D
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
chr6_-_43543702 0.14 ENST00000265351.7
XPO5
exportin 5
chr17_-_27278445 0.14 ENST00000268756.3
ENST00000584685.1
PHF12
PHD finger protein 12
chr5_+_102201722 0.14 ENST00000274392.9
ENST00000455264.2
PAM
peptidylglycine alpha-amidating monooxygenase
chr16_-_29910365 0.14 ENST00000346932.5
ENST00000350527.3
ENST00000537485.1
ENST00000568380.1
SEZ6L2
seizure related 6 homolog (mouse)-like 2
chr5_+_118788433 0.14 ENST00000414835.2
HSD17B4
hydroxysteroid (17-beta) dehydrogenase 4
chr7_-_100808394 0.13 ENST00000445482.2
VGF
VGF nerve growth factor inducible
chr14_+_31343747 0.13 ENST00000216361.4
ENST00000396618.3
ENST00000475087.1
COCH
cochlin
chr5_-_80689945 0.13 ENST00000307624.3
ACOT12
acyl-CoA thioesterase 12
chr1_+_113217309 0.13 ENST00000544796.1
ENST00000369644.1
MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr17_+_4981535 0.13 ENST00000318833.3
ZFP3
ZFP3 zinc finger protein
chr19_+_36346734 0.13 ENST00000586102.3
KIRREL2
kin of IRRE like 2 (Drosophila)
chrX_+_70521584 0.13 ENST00000373829.3
ENST00000538820.1
ITGB1BP2
integrin beta 1 binding protein (melusin) 2
chr4_+_95373037 0.13 ENST00000359265.4
ENST00000437932.1
ENST00000380180.3
ENST00000318007.5
ENST00000450793.1
ENST00000538141.1
ENST00000317968.4
ENST00000512274.1
ENST00000503974.1
ENST00000504489.1
ENST00000542407.1
PDLIM5
PDZ and LIM domain 5
chr7_-_148725733 0.13 ENST00000286091.4
PDIA4
protein disulfide isomerase family A, member 4
chr19_-_14316980 0.13 ENST00000361434.3
ENST00000340736.6
LPHN1
latrophilin 1
chr8_-_144897549 0.13 ENST00000356994.2
ENST00000320476.3
SCRIB
scribbled planar cell polarity protein
chr19_+_17858509 0.13 ENST00000594202.1
ENST00000252771.7
ENST00000389133.4
FCHO1
FCH domain only 1
chr6_-_43596899 0.13 ENST00000307126.5
ENST00000452781.1
GTPBP2
GTP binding protein 2
chr3_+_184056614 0.13 ENST00000453072.1
FAM131A
family with sequence similarity 131, member A
chr12_+_50017184 0.13 ENST00000548825.2
PRPF40B
PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
chr19_+_4304585 0.13 ENST00000221856.6
FSD1
fibronectin type III and SPRY domain containing 1
chr1_-_8075693 0.13 ENST00000467067.1
ERRFI1
ERBB receptor feedback inhibitor 1
chr9_+_108006880 0.12 ENST00000374723.1
ENST00000374720.3
ENST00000374724.1
SLC44A1
solute carrier family 44 (choline transporter), member 1
chr8_+_128747661 0.12 ENST00000259523.6
MYC
v-myc avian myelocytomatosis viral oncogene homolog
chr17_-_56606705 0.12 ENST00000317268.3
SEPT4
septin 4
chr4_-_2420357 0.12 ENST00000511071.1
ENST00000509171.1
ENST00000290974.2
ZFYVE28
zinc finger, FYVE domain containing 28
chr19_-_45737469 0.12 ENST00000413988.1
EXOC3L2
exocyst complex component 3-like 2
chr14_-_39901618 0.12 ENST00000554932.1
ENST00000298097.7
FBXO33
F-box protein 33
chr7_+_128784712 0.12 ENST00000289407.4
TSPAN33
tetraspanin 33
chr8_-_144897138 0.12 ENST00000377533.3
SCRIB
scribbled planar cell polarity protein
chr2_+_198570081 0.12 ENST00000282276.6
MARS2
methionyl-tRNA synthetase 2, mitochondrial
chr19_+_35521699 0.12 ENST00000415950.3
SCN1B
sodium channel, voltage-gated, type I, beta subunit
chr12_-_52887034 0.12 ENST00000330722.6
KRT6A
keratin 6A
chr6_-_75915757 0.12 ENST00000322507.8
COL12A1
collagen, type XII, alpha 1
chr12_+_110152033 0.12 ENST00000538780.1
FAM222A
family with sequence similarity 222, member A
chr20_-_31172598 0.12 ENST00000201961.2
C20orf112
chromosome 20 open reading frame 112
chr22_+_38054721 0.12 ENST00000215904.6
PDXP
pyridoxal (pyridoxine, vitamin B6) phosphatase
chr11_-_6341844 0.12 ENST00000303927.3
PRKCDBP
protein kinase C, delta binding protein
chr17_+_73512594 0.12 ENST00000333213.6
TSEN54
TSEN54 tRNA splicing endonuclease subunit
chr15_+_50474385 0.12 ENST00000267842.5
SLC27A2
solute carrier family 27 (fatty acid transporter), member 2
chr20_+_13202418 0.11 ENST00000262487.4
ISM1
isthmin 1, angiogenesis inhibitor
chr2_+_220436917 0.11 ENST00000243786.2
INHA
inhibin, alpha
chr4_-_71705027 0.11 ENST00000545193.1
GRSF1
G-rich RNA sequence binding factor 1
chr14_+_70346125 0.11 ENST00000361956.3
ENST00000381280.4
SMOC1
SPARC related modular calcium binding 1
chr2_+_47168313 0.11 ENST00000319190.5
ENST00000394850.2
ENST00000536057.1
TTC7A
tetratricopeptide repeat domain 7A
chr12_+_49212261 0.11 ENST00000547818.1
ENST00000547392.1
CACNB3
calcium channel, voltage-dependent, beta 3 subunit
chr5_+_118788138 0.11 ENST00000256216.6
HSD17B4
hydroxysteroid (17-beta) dehydrogenase 4
chr7_-_127672146 0.11 ENST00000476782.1
LRRC4
leucine rich repeat containing 4
chr11_-_65359947 0.11 ENST00000597463.1
AP001362.1
Uncharacterized protein
chr1_+_39456895 0.11 ENST00000432648.3
ENST00000446189.2
ENST00000372984.4
AKIRIN1
akirin 1
chr2_-_37899323 0.11 ENST00000295324.3
ENST00000457889.1
CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr4_+_48343339 0.11 ENST00000264313.6
SLAIN2
SLAIN motif family, member 2
chr2_+_232063436 0.11 ENST00000440107.1
ARMC9
armadillo repeat containing 9
chr16_-_88772670 0.11 ENST00000562544.1
RNF166
ring finger protein 166
chr8_+_128747757 0.11 ENST00000517291.1
MYC
v-myc avian myelocytomatosis viral oncogene homolog
chr2_+_105953972 0.11 ENST00000410049.1
C2orf49
chromosome 2 open reading frame 49
chr19_+_39989535 0.11 ENST00000356433.5
DLL3
delta-like 3 (Drosophila)
chr8_-_37594944 0.11 ENST00000330539.1
RP11-863K10.7
Uncharacterized protein
chr1_-_52344471 0.11 ENST00000352171.7
ENST00000354831.7
NRD1
nardilysin (N-arginine dibasic convertase)
chr15_+_79603479 0.11 ENST00000424155.2
ENST00000536821.1
TMED3
transmembrane emp24 protein transport domain containing 3
chr11_+_1049862 0.11 ENST00000534584.1
RP13-870H17.3
RP13-870H17.3
chr11_-_695162 0.11 ENST00000338675.6
DEAF1
DEAF1 transcription factor
chr11_+_22646739 0.11 ENST00000428556.2
AC103801.2
AC103801.2
chr12_-_118541692 0.11 ENST00000538357.1
VSIG10
V-set and immunoglobulin domain containing 10
chr2_-_40679148 0.11 ENST00000417271.1
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr14_-_24551137 0.11 ENST00000396995.1
NRL
neural retina leucine zipper
chr16_+_67465016 0.10 ENST00000326152.5
HSD11B2
hydroxysteroid (11-beta) dehydrogenase 2
chr7_-_148725544 0.10 ENST00000413966.1
PDIA4
protein disulfide isomerase family A, member 4
chrX_-_40036520 0.10 ENST00000406200.2
ENST00000378455.4
ENST00000342274.4
BCOR
BCL6 corepressor
chr3_-_196669298 0.10 ENST00000411704.1
ENST00000452404.2
NCBP2
nuclear cap binding protein subunit 2, 20kDa
chr19_-_39805976 0.10 ENST00000248668.4
LRFN1
leucine rich repeat and fibronectin type III domain containing 1
chr19_-_5340730 0.10 ENST00000372412.4
ENST00000357368.4
ENST00000262963.6
ENST00000348075.2
ENST00000353284.2
PTPRS
protein tyrosine phosphatase, receptor type, S
chr12_+_50017327 0.10 ENST00000261897.1
PRPF40B
PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
chr16_+_23847339 0.10 ENST00000303531.7
PRKCB
protein kinase C, beta
chr19_+_16187085 0.10 ENST00000300933.4
TPM4
tropomyosin 4
chr8_-_101963482 0.10 ENST00000419477.2
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr7_-_99766191 0.10 ENST00000423751.1
ENST00000360039.4
GAL3ST4
galactose-3-O-sulfotransferase 4
chr12_-_54813229 0.10 ENST00000293379.4
ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr8_+_86376081 0.10 ENST00000285379.5
CA2
carbonic anhydrase II
chr5_+_61602236 0.10 ENST00000514082.1
ENST00000407818.3
KIF2A
kinesin heavy chain member 2A
chr1_+_150293921 0.10 ENST00000324862.6
PRPF3
pre-mRNA processing factor 3
chr17_-_7216939 0.10 ENST00000573684.1
GPS2
G protein pathway suppressor 2
chr13_-_36705425 0.10 ENST00000255448.4
ENST00000360631.3
ENST00000379892.4
DCLK1
doublecortin-like kinase 1
chr3_-_165555200 0.10 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
BCHE
butyrylcholinesterase
chr11_-_10829851 0.10 ENST00000532082.1
EIF4G2
eukaryotic translation initiation factor 4 gamma, 2
chr4_-_74124502 0.10 ENST00000358602.4
ENST00000330838.6
ENST00000561029.1
ANKRD17
ankyrin repeat domain 17
chr17_-_18950310 0.10 ENST00000573099.1
GRAP
GRB2-related adaptor protein
chr14_+_100150622 0.10 ENST00000261835.3
CYP46A1
cytochrome P450, family 46, subfamily A, polypeptide 1
chrX_-_117250740 0.10 ENST00000371882.1
ENST00000540167.1
ENST00000545703.1
KLHL13
kelch-like family member 13
chr15_+_40544749 0.10 ENST00000559617.1
ENST00000560684.1
PAK6
p21 protein (Cdc42/Rac)-activated kinase 6

Network of associatons between targets according to the STRING database.

First level regulatory network of NHLH1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.2 0.6 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.1 0.7 GO:0035617 stress granule disassembly(GO:0035617)
0.1 0.5 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.1 0.6 GO:0072185 metanephric cap development(GO:0072185) metanephric cap morphogenesis(GO:0072186) metanephric cap mesenchymal cell proliferation involved in metanephros development(GO:0090094)
0.1 0.3 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
0.1 0.3 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
0.1 0.6 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
0.1 0.2 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.1 0.3 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.1 0.2 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.1 0.3 GO:0018032 protein amidation(GO:0018032)
0.1 0.3 GO:0034699 response to luteinizing hormone(GO:0034699)
0.1 0.3 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.1 0.5 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.1 0.2 GO:0070101 positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.1 0.3 GO:1990523 bone regeneration(GO:1990523)
0.1 0.2 GO:0046833 snRNA export from nucleus(GO:0006408) positive regulation of RNA export from nucleus(GO:0046833)
0.0 0.2 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.1 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.0 0.1 GO:0035281 pre-miRNA export from nucleus(GO:0035281)
0.0 0.2 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.0 0.2 GO:0048242 regulation of epinephrine secretion(GO:0014060) negative regulation of epinephrine secretion(GO:0032811) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625) epinephrine secretion(GO:0048242)
0.0 0.2 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.1 GO:0001897 cytolysis by symbiont of host cells(GO:0001897)
0.0 0.1 GO:0031247 actin rod assembly(GO:0031247)
0.0 0.4 GO:0042695 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0 0.2 GO:0070346 positive regulation of fat cell proliferation(GO:0070346)
0.0 0.6 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.2 GO:0072240 ascending thin limb development(GO:0072021) DCT cell differentiation(GO:0072069) metanephric ascending thin limb development(GO:0072218) metanephric DCT cell differentiation(GO:0072240)
0.0 0.1 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.0 0.1 GO:0042938 dipeptide transport(GO:0042938)
0.0 0.1 GO:0014016 neuroblast differentiation(GO:0014016)
0.0 0.2 GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
0.0 0.4 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.2 GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371)
0.0 0.8 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.2 GO:0072553 terminal button organization(GO:0072553)
0.0 0.2 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.0 0.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.1 GO:0045872 regulation of rhodopsin gene expression(GO:0007468) positive regulation of rhodopsin gene expression(GO:0045872)
0.0 0.1 GO:0046882 negative regulation of B cell differentiation(GO:0045578) negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.0 0.2 GO:1902075 cellular response to salt(GO:1902075)
0.0 0.2 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.0 0.1 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.2 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.6 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:0043309 regulation of eosinophil degranulation(GO:0043309) positive regulation of eosinophil degranulation(GO:0043311) regulation of eosinophil activation(GO:1902566) positive regulation of eosinophil activation(GO:1902568)
0.0 0.1 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0 0.1 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.1 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.0 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.1 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.0 0.1 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.0 0.2 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.2 GO:0003344 pericardium morphogenesis(GO:0003344)
0.0 0.0 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.0 0.1 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.1 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.1 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.0 0.2 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.1 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.3 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.0 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0 0.2 GO:0071680 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0 0.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.1 GO:0042426 choline catabolic process(GO:0042426)
0.0 0.1 GO:1902723 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0 0.0 GO:0008057 eye pigment granule organization(GO:0008057)
0.0 0.0 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057)
0.0 0.4 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.0 GO:0039533 regulation of MDA-5 signaling pathway(GO:0039533)
0.0 0.0 GO:0090472 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.0 0.1 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.1 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.1 GO:0085020 protein K6-linked ubiquitination(GO:0085020)
0.0 0.1 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.1 GO:0036115 fatty-acyl-CoA catabolic process(GO:0036115)
0.0 0.1 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.2 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.0 0.0 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.0 0.1 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.0 0.0 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.0 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.0 0.3 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.1 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.0 0.1 GO:0071313 cellular response to caffeine(GO:0071313)
0.0 0.3 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.2 GO:0005846 nuclear cap binding complex(GO:0005846)
0.0 0.1 GO:0042565 RNA nuclear export complex(GO:0042565)
0.0 0.1 GO:0005595 collagen type XII trimer(GO:0005595)
0.0 0.5 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.2 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.2 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.1 GO:0032173 septin ring(GO:0005940) septin collar(GO:0032173)
0.0 0.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0034457 Mpp10 complex(GO:0034457)
0.0 0.1 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.0 0.2 GO:0016600 flotillin complex(GO:0016600)
0.0 0.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.1 GO:0032044 DSIF complex(GO:0032044)
0.0 0.1 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.3 GO:0097227 sperm annulus(GO:0097227)
0.0 0.0 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.4 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.0 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.3 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.9 GO:0045095 keratin filament(GO:0045095)
0.0 0.2 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.3 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.2 GO:0042587 glycogen granule(GO:0042587)
0.0 0.1 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.0 GO:0030686 90S preribosome(GO:0030686)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0009041 uridylate kinase activity(GO:0009041)
0.1 0.5 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.1 0.6 GO:0044594 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.1 0.3 GO:0070123 transforming growth factor beta receptor activity, type III(GO:0070123)
0.1 0.3 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.5 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.1 0.3 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.1 0.4 GO:0050436 microfibril binding(GO:0050436)
0.1 0.3 GO:0019863 IgE binding(GO:0019863)
0.1 0.3 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.1 0.2 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.1 0.2 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.2 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.1 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.0 0.2 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.1 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.3 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.2 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.1 GO:0008193 tRNA guanylyltransferase activity(GO:0008193)
0.0 0.3 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.2 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0 0.6 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.1 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 0.1 GO:0001855 complement component C4b binding(GO:0001855)
0.0 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.4 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.1 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.7 GO:0031489 myosin V binding(GO:0031489)
0.0 0.7 GO:0001848 complement binding(GO:0001848)
0.0 0.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.1 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.0 0.3 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.1 GO:0034711 inhibin binding(GO:0034711)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.5 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.1 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.3 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.0 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.2 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.1 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.1 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.2 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.1 GO:0023025 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.1 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.1 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.2 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.1 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 0.1 GO:0003785 actin monomer binding(GO:0003785)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.6 ST G ALPHA S PATHWAY G alpha s Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.7 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.8 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.6 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.5 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.5 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.1 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.2 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.4 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat