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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for NFKB1

Z-value: 1.10

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Transcription factors associated with NFKB1

Gene Symbol Gene ID Gene Info
NFKB1
ENSG00000109320.7 nuclear factor kappa B subunit 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFKB1hg19_v2_chr4_+_103423055_1034231120.749.6e-02Click!

Activity profile of NFKB1 motif

Sorted Z-values of NFKB1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_74212073 1.32 ENST00000441217.1
AC073046.25
AC073046.25
chr11_-_64570624 1.30 ENST00000439069.1
MAP4K2
mitogen-activated protein kinase kinase kinase kinase 2
chr15_+_76352178 0.95 ENST00000388942.3
C15orf27
chromosome 15 open reading frame 27
chr5_+_35852797 0.93 ENST00000508941.1
IL7R
interleukin 7 receptor
chr3_-_111852061 0.89 ENST00000488580.1
ENST00000460387.2
ENST00000484193.1
ENST00000487901.1
GCSAM
germinal center-associated, signaling and motility
chr12_-_62997214 0.88 ENST00000408887.2
C12orf61
chromosome 12 open reading frame 61
chr14_-_103589246 0.87 ENST00000558224.1
ENST00000560742.1
LINC00677
long intergenic non-protein coding RNA 677
chr20_+_1115821 0.86 ENST00000435720.1
PSMF1
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr19_+_41222998 0.82 ENST00000263370.2
ITPKC
inositol-trisphosphate 3-kinase C
chr10_+_104154229 0.76 ENST00000428099.1
ENST00000369966.3
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr19_+_10527449 0.76 ENST00000592685.1
ENST00000380702.2
PDE4A
phosphodiesterase 4A, cAMP-specific
chr11_+_19799327 0.72 ENST00000540292.1
NAV2
neuron navigator 2
chr7_+_69064566 0.70 ENST00000403018.2
AUTS2
autism susceptibility candidate 2
chr16_+_29823427 0.70 ENST00000358758.7
ENST00000567659.1
ENST00000572820.1
PRRT2
proline-rich transmembrane protein 2
chr16_-_66959429 0.66 ENST00000420652.1
ENST00000299759.6
RRAD
Ras-related associated with diabetes
chr9_-_140115775 0.63 ENST00000391553.1
ENST00000392827.1
RNF208
ring finger protein 208
chr4_-_122085469 0.62 ENST00000057513.3
TNIP3
TNFAIP3 interacting protein 3
chr19_-_41222775 0.62 ENST00000324464.3
ENST00000450541.1
ENST00000594720.1
ADCK4
aarF domain containing kinase 4
chr15_+_85923856 0.59 ENST00000560302.1
ENST00000394518.2
ENST00000361243.2
ENST00000560256.1
AKAP13
A kinase (PRKA) anchor protein 13
chr18_-_72920372 0.58 ENST00000581620.1
ENST00000582437.1
ZADH2
zinc binding alcohol dehydrogenase domain containing 2
chr11_+_19798964 0.53 ENST00000527559.2
NAV2
neuron navigator 2
chr1_+_110453462 0.52 ENST00000488198.1
CSF1
colony stimulating factor 1 (macrophage)
chr11_+_118478313 0.51 ENST00000356063.5
PHLDB1
pleckstrin homology-like domain, family B, member 1
chr11_+_113930955 0.50 ENST00000535700.1
ZBTB16
zinc finger and BTB domain containing 16
chr7_+_69064300 0.50 ENST00000342771.4
AUTS2
autism susceptibility candidate 2
chr7_-_155601766 0.50 ENST00000430104.1
SHH
sonic hedgehog
chr17_+_38024417 0.50 ENST00000348931.4
ENST00000583811.1
ENST00000584588.1
ENST00000377940.3
ZPBP2
zona pellucida binding protein 2
chr6_+_31540056 0.49 ENST00000418386.2
LTA
lymphotoxin alpha
chr1_+_89990378 0.49 ENST00000449440.1
LRRC8B
leucine rich repeat containing 8 family, member B
chr1_-_21978312 0.48 ENST00000359708.4
ENST00000290101.4
RAP1GAP
RAP1 GTPase activating protein
chr17_-_1419941 0.48 ENST00000498390.1
INPP5K
inositol polyphosphate-5-phosphatase K
chr12_-_46121554 0.47 ENST00000609803.1
LINC00938
long intergenic non-protein coding RNA 938
chr15_+_85923797 0.46 ENST00000559362.1
AKAP13
A kinase (PRKA) anchor protein 13
chr19_-_47734448 0.45 ENST00000439096.2
BBC3
BCL2 binding component 3
chr19_-_4338783 0.45 ENST00000601482.1
ENST00000600324.1
STAP2
signal transducing adaptor family member 2
chr20_+_44746939 0.43 ENST00000372276.3
CD40
CD40 molecule, TNF receptor superfamily member 5
chr5_+_170846640 0.42 ENST00000274625.5
FGF18
fibroblast growth factor 18
chr3_-_187455680 0.42 ENST00000438077.1
BCL6
B-cell CLL/lymphoma 6
chr14_-_69262947 0.42 ENST00000557086.1
ZFP36L1
ZFP36 ring finger protein-like 1
chr7_-_100881041 0.40 ENST00000412417.1
ENST00000414035.1
CLDN15
claudin 15
chr3_+_9691117 0.40 ENST00000353332.5
ENST00000420925.1
ENST00000296003.4
ENST00000351233.5
MTMR14
myotubularin related protein 14
chr10_-_105437909 0.40 ENST00000540321.1
SH3PXD2A
SH3 and PX domains 2A
chr19_-_39390440 0.39 ENST00000249396.7
ENST00000414941.1
ENST00000392081.2
SIRT2
sirtuin 2
chr11_-_64570706 0.39 ENST00000294066.2
ENST00000377350.3
MAP4K2
mitogen-activated protein kinase kinase kinase kinase 2
chr1_+_201979743 0.39 ENST00000446188.1
ELF3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr17_+_40440481 0.39 ENST00000590726.2
ENST00000452307.2
ENST00000444283.1
ENST00000588868.1
STAT5A
signal transducer and activator of transcription 5A
chr16_+_29823552 0.39 ENST00000300797.6
PRRT2
proline-rich transmembrane protein 2
chr1_+_110453203 0.39 ENST00000357302.4
ENST00000344188.5
ENST00000329608.6
CSF1
colony stimulating factor 1 (macrophage)
chr15_-_89438742 0.39 ENST00000562281.1
ENST00000562889.1
ENST00000359595.3
HAPLN3
hyaluronan and proteoglycan link protein 3
chr5_-_150467221 0.38 ENST00000522226.1
TNIP1
TNFAIP3 interacting protein 1
chrX_-_30595959 0.38 ENST00000378962.3
CXorf21
chromosome X open reading frame 21
chrX_-_63005405 0.38 ENST00000374878.1
ENST00000437457.2
ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr19_-_39390350 0.38 ENST00000447739.1
ENST00000358931.5
ENST00000407552.1
SIRT2
sirtuin 2
chr17_-_61777090 0.37 ENST00000578061.1
LIMD2
LIM domain containing 2
chr19_+_42363917 0.37 ENST00000598742.1
RPS19
ribosomal protein S19
chr2_+_208394658 0.37 ENST00000421139.1
CREB1
cAMP responsive element binding protein 1
chr7_-_56101826 0.37 ENST00000421626.1
PSPH
phosphoserine phosphatase
chr9_-_117267717 0.36 ENST00000374057.3
DFNB31
deafness, autosomal recessive 31
chr1_+_201979645 0.36 ENST00000367284.5
ENST00000367283.3
ELF3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr20_+_35090150 0.35 ENST00000340491.4
DLGAP4
discs, large (Drosophila) homolog-associated protein 4
chr7_-_100881109 0.35 ENST00000308344.5
CLDN15
claudin 15
chr17_+_21191341 0.35 ENST00000526076.2
ENST00000361818.5
ENST00000316920.6
MAP2K3
mitogen-activated protein kinase kinase 3
chr17_-_61776522 0.34 ENST00000582055.1
LIMD2
LIM domain containing 2
chr2_-_206950996 0.34 ENST00000414320.1
INO80D
INO80 complex subunit D
chr14_+_32798547 0.34 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
AKAP6
A kinase (PRKA) anchor protein 6
chr1_+_159796534 0.34 ENST00000289707.5
SLAMF8
SLAM family member 8
chr19_-_39390212 0.34 ENST00000437828.1
SIRT2
sirtuin 2
chr4_-_146859623 0.33 ENST00000379448.4
ENST00000513320.1
ZNF827
zinc finger protein 827
chr14_+_24439148 0.33 ENST00000543805.1
ENST00000534993.1
DHRS4L2
dehydrogenase/reductase (SDR family) member 4 like 2
chr1_+_67632083 0.33 ENST00000347310.5
ENST00000371002.1
IL23R
interleukin 23 receptor
chr12_-_58131931 0.33 ENST00000547588.1
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr10_-_29923893 0.32 ENST00000355867.4
SVIL
supervillin
chr10_+_12391685 0.32 ENST00000378845.1
CAMK1D
calcium/calmodulin-dependent protein kinase ID
chr11_+_118307179 0.31 ENST00000534358.1
ENST00000531904.2
ENST00000389506.5
ENST00000354520.4
KMT2A
lysine (K)-specific methyltransferase 2A
chr4_+_185395947 0.31 ENST00000605834.1
RP11-326I11.3
RP11-326I11.3
chr17_+_25799008 0.31 ENST00000583370.1
ENST00000398988.3
ENST00000268763.6
KSR1
kinase suppressor of ras 1
chr11_-_66313699 0.31 ENST00000526986.1
ENST00000310442.3
ZDHHC24
zinc finger, DHHC-type containing 24
chrX_-_100129320 0.31 ENST00000372966.3
NOX1
NADPH oxidase 1
chr7_+_100273736 0.31 ENST00000412215.1
ENST00000393924.1
GNB2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr5_-_150466692 0.31 ENST00000315050.7
ENST00000523338.1
ENST00000522100.1
TNIP1
TNFAIP3 interacting protein 1
chr6_-_33160231 0.30 ENST00000395194.1
ENST00000457788.1
ENST00000341947.2
ENST00000357486.1
ENST00000374714.1
ENST00000374713.1
ENST00000395197.1
ENST00000374712.1
ENST00000361917.1
ENST00000374708.4
COL11A2
collagen, type XI, alpha 2
chr19_+_42381173 0.30 ENST00000221972.3
CD79A
CD79a molecule, immunoglobulin-associated alpha
chr1_+_110453514 0.30 ENST00000369802.3
ENST00000420111.2
CSF1
colony stimulating factor 1 (macrophage)
chr19_+_39574945 0.30 ENST00000331256.5
PAPL
Iron/zinc purple acid phosphatase-like protein
chr6_-_32122106 0.30 ENST00000428778.1
PRRT1
proline-rich transmembrane protein 1
chr17_-_56065540 0.30 ENST00000583932.1
VEZF1
vascular endothelial zinc finger 1
chr16_+_88636789 0.29 ENST00000301011.5
ENST00000452588.2
ZC3H18
zinc finger CCCH-type containing 18
chr2_+_38893208 0.29 ENST00000410063.1
GALM
galactose mutarotase (aldose 1-epimerase)
chr11_+_35639735 0.29 ENST00000317811.4
FJX1
four jointed box 1 (Drosophila)
chrX_-_100129128 0.29 ENST00000372960.4
ENST00000372964.1
ENST00000217885.5
NOX1
NADPH oxidase 1
chr1_+_28285973 0.29 ENST00000373884.5
XKR8
XK, Kell blood group complex subunit-related family, member 8
chr11_+_72525353 0.28 ENST00000321297.5
ENST00000534905.1
ENST00000540567.1
ATG16L2
autophagy related 16-like 2 (S. cerevisiae)
chr12_-_9913489 0.28 ENST00000228434.3
ENST00000536709.1
CD69
CD69 molecule
chr1_+_26872324 0.28 ENST00000531382.1
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr17_-_1419914 0.28 ENST00000397335.3
ENST00000574561.1
INPP5K
inositol polyphosphate-5-phosphatase K
chr19_+_51728316 0.28 ENST00000436584.2
ENST00000421133.2
ENST00000391796.3
ENST00000262262.4
CD33
CD33 molecule
chr10_+_89124746 0.28 ENST00000465545.1
NUTM2D
NUT family member 2D
chr12_+_57623907 0.28 ENST00000553529.1
ENST00000554310.1
SHMT2
serine hydroxymethyltransferase 2 (mitochondrial)
chr1_-_161279749 0.28 ENST00000533357.1
ENST00000360451.6
ENST00000336559.4
MPZ
myelin protein zero
chr22_-_28490123 0.28 ENST00000442232.1
TTC28
tetratricopeptide repeat domain 28
chr20_+_44746885 0.28 ENST00000372285.3
CD40
CD40 molecule, TNF receptor superfamily member 5
chr19_+_2476116 0.28 ENST00000215631.4
ENST00000587345.1
GADD45B
growth arrest and DNA-damage-inducible, beta
chr17_-_1420006 0.27 ENST00000320345.6
ENST00000406424.4
INPP5K
inositol polyphosphate-5-phosphatase K
chr1_-_153935983 0.27 ENST00000537590.1
ENST00000356205.4
SLC39A1
solute carrier family 39 (zinc transporter), member 1
chr1_-_153588334 0.27 ENST00000476873.1
S100A14
S100 calcium binding protein A14
chr9_+_127054217 0.27 ENST00000394199.2
ENST00000546191.1
NEK6
NIMA-related kinase 6
chr12_+_11802753 0.27 ENST00000396373.4
ETV6
ets variant 6
chr12_+_57624059 0.27 ENST00000557427.1
SHMT2
serine hydroxymethyltransferase 2 (mitochondrial)
chr12_+_57623477 0.27 ENST00000557487.1
ENST00000555634.1
ENST00000556689.1
SHMT2
serine hydroxymethyltransferase 2 (mitochondrial)
chr19_-_46145696 0.27 ENST00000588172.1
EML2
echinoderm microtubule associated protein like 2
chr12_+_50690489 0.27 ENST00000598429.1
AC140061.12
Uncharacterized protein
chr19_+_42364460 0.26 ENST00000593863.1
RPS19
ribosomal protein S19
chr19_-_4182530 0.26 ENST00000601571.1
ENST00000601488.1
ENST00000305232.6
ENST00000381935.3
ENST00000337491.2
SIRT6
sirtuin 6
chr11_-_72853267 0.26 ENST00000409418.4
FCHSD2
FCH and double SH3 domains 2
chr17_-_4852332 0.26 ENST00000572383.1
PFN1
profilin 1
chr6_-_33168391 0.26 ENST00000374685.4
ENST00000413614.2
ENST00000374680.3
RXRB
retinoid X receptor, beta
chr19_-_4182497 0.25 ENST00000597896.1
SIRT6
sirtuin 6
chr5_-_137090028 0.25 ENST00000314940.4
HNRNPA0
heterogeneous nuclear ribonucleoprotein A0
chr19_+_45504688 0.25 ENST00000221452.8
ENST00000540120.1
ENST00000505236.1
RELB
v-rel avian reticuloendotheliosis viral oncogene homolog B
chr3_+_52279902 0.25 ENST00000457454.1
PPM1M
protein phosphatase, Mg2+/Mn2+ dependent, 1M
chr8_+_72755367 0.25 ENST00000537896.1
RP11-383H13.1
Protein LOC100132891; cDNA FLJ53548
chr9_-_136344197 0.25 ENST00000414172.1
ENST00000371897.4
SLC2A6
solute carrier family 2 (facilitated glucose transporter), member 6
chr19_+_42364313 0.25 ENST00000601492.1
ENST00000600467.1
ENST00000221975.2
RPS19
ribosomal protein S19
chr8_-_9008206 0.25 ENST00000310455.3
PPP1R3B
protein phosphatase 1, regulatory subunit 3B
chr16_+_28834531 0.24 ENST00000570200.1
ATXN2L
ataxin 2-like
chr14_-_74226961 0.24 ENST00000286523.5
ENST00000435371.1
ELMSAN1
ELM2 and Myb/SANT-like domain containing 1
chr11_-_61596753 0.24 ENST00000448607.1
ENST00000421879.1
FADS1
fatty acid desaturase 1
chr12_+_57624085 0.24 ENST00000553474.1
SHMT2
serine hydroxymethyltransferase 2 (mitochondrial)
chr1_+_183441600 0.24 ENST00000367537.3
SMG7
SMG7 nonsense mediated mRNA decay factor
chr2_-_61108449 0.24 ENST00000439412.1
ENST00000452343.1
AC010733.4
AC010733.4
chr4_-_76957214 0.24 ENST00000306621.3
CXCL11
chemokine (C-X-C motif) ligand 11
chr5_-_150460914 0.24 ENST00000389378.2
TNIP1
TNFAIP3 interacting protein 1
chr19_-_40324255 0.24 ENST00000593685.1
ENST00000600611.1
DYRK1B
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
chr4_-_185395672 0.24 ENST00000393593.3
IRF2
interferon regulatory factor 2
chr1_-_16302608 0.24 ENST00000375743.4
ENST00000375733.2
ZBTB17
zinc finger and BTB domain containing 17
chr7_+_44663908 0.23 ENST00000543843.1
OGDH
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr4_-_122148620 0.23 ENST00000509841.1
TNIP3
TNFAIP3 interacting protein 3
chr12_-_49259643 0.23 ENST00000309739.5
RND1
Rho family GTPase 1
chr16_+_57126428 0.23 ENST00000290776.8
CPNE2
copine II
chr14_-_69262916 0.23 ENST00000553375.1
ZFP36L1
ZFP36 ring finger protein-like 1
chr1_-_153935938 0.22 ENST00000368621.1
ENST00000368623.3
SLC39A1
solute carrier family 39 (zinc transporter), member 1
chr12_+_7053228 0.22 ENST00000540506.2
C12orf57
chromosome 12 open reading frame 57
chr14_-_69446034 0.22 ENST00000193403.6
ACTN1
actinin, alpha 1
chr12_+_57623869 0.22 ENST00000414700.3
ENST00000557703.1
SHMT2
serine hydroxymethyltransferase 2 (mitochondrial)
chr7_-_44530479 0.22 ENST00000355451.7
NUDCD3
NudC domain containing 3
chr14_-_61190754 0.22 ENST00000216513.4
SIX4
SIX homeobox 4
chr14_+_73704201 0.22 ENST00000340738.5
ENST00000427855.1
ENST00000381166.3
PAPLN
papilin, proteoglycan-like sulfated glycoprotein
chr15_+_75041184 0.22 ENST00000343932.4
CYP1A2
cytochrome P450, family 1, subfamily A, polypeptide 2
chr12_+_7052974 0.22 ENST00000544681.1
ENST00000537087.1
C12orf57
chromosome 12 open reading frame 57
chr6_-_31613280 0.21 ENST00000453833.1
BAG6
BCL2-associated athanogene 6
chr11_+_560956 0.21 ENST00000397582.3
ENST00000344375.4
ENST00000397583.3
RASSF7
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
chr9_+_134103496 0.21 ENST00000498010.1
ENST00000476004.1
ENST00000528406.1
NUP214
nucleoporin 214kDa
chr20_+_57430162 0.21 ENST00000450130.1
ENST00000349036.3
ENST00000423897.1
GNAS
GNAS complex locus
chr10_+_13141585 0.21 ENST00000378764.2
OPTN
optineurin
chr17_-_7154984 0.21 ENST00000574322.1
CTDNEP1
CTD nuclear envelope phosphatase 1
chr2_-_157189180 0.21 ENST00000539077.1
ENST00000424077.1
ENST00000426264.1
ENST00000339562.4
ENST00000421709.1
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr12_+_57624119 0.21 ENST00000555773.1
ENST00000554975.1
ENST00000449049.3
ENST00000393827.4
SHMT2
serine hydroxymethyltransferase 2 (mitochondrial)
chr1_-_151299842 0.21 ENST00000438243.2
ENST00000489223.2
ENST00000368873.1
ENST00000430800.1
ENST00000368872.1
PI4KB
phosphatidylinositol 4-kinase, catalytic, beta
chr3_+_9439400 0.21 ENST00000450326.1
ENST00000402198.1
ENST00000402466.1
SETD5
SET domain containing 5
chr11_-_72852958 0.21 ENST00000458644.2
FCHSD2
FCH and double SH3 domains 2
chr6_+_106534192 0.21 ENST00000369091.2
ENST00000369096.4
PRDM1
PR domain containing 1, with ZNF domain
chr8_-_145582118 0.21 ENST00000455319.2
ENST00000331890.5
FBXL6
F-box and leucine-rich repeat protein 6
chr9_+_82187630 0.20 ENST00000265284.6
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr2_+_176957619 0.20 ENST00000392539.3
HOXD13
homeobox D13
chr6_+_292253 0.20 ENST00000603453.1
ENST00000605315.1
ENST00000603881.1
DUSP22
dual specificity phosphatase 22
chr17_-_17740287 0.20 ENST00000355815.4
ENST00000261646.5
SREBF1
sterol regulatory element binding transcription factor 1
chr14_-_51297360 0.20 ENST00000496749.1
NIN
ninein (GSK3B interacting protein)
chr20_-_2451395 0.20 ENST00000339610.6
ENST00000381342.2
ENST00000438552.2
SNRPB
small nuclear ribonucleoprotein polypeptides B and B1
chr4_+_103422499 0.20 ENST00000511926.1
ENST00000507079.1
NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr17_+_40440094 0.20 ENST00000546010.2
STAT5A
signal transducer and activator of transcription 5A
chr10_+_13142075 0.20 ENST00000378757.2
ENST00000430081.1
ENST00000378752.3
ENST00000378748.3
OPTN
optineurin
chr2_-_242447732 0.20 ENST00000439101.1
ENST00000424537.1
ENST00000401869.1
ENST00000436402.1
STK25
serine/threonine kinase 25
chr22_-_39151434 0.20 ENST00000439339.1
SUN2
Sad1 and UNC84 domain containing 2
chr10_+_99609996 0.20 ENST00000370602.1
GOLGA7B
golgin A7 family, member B
chr16_+_67571351 0.20 ENST00000428437.2
ENST00000569253.1
FAM65A
family with sequence similarity 65, member A
chr11_+_73000449 0.19 ENST00000535931.1
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr17_-_39968406 0.19 ENST00000393928.1
LEPREL4
leprecan-like 4
chr17_+_40996590 0.19 ENST00000253799.3
ENST00000452774.2
AOC2
amine oxidase, copper containing 2 (retina-specific)
chr3_+_159557637 0.19 ENST00000445224.2
SCHIP1
schwannomin interacting protein 1
chr16_-_28223166 0.19 ENST00000304658.5
XPO6
exportin 6
chr16_+_57126482 0.19 ENST00000537605.1
ENST00000535318.2
CPNE2
copine II
chr11_+_119056178 0.19 ENST00000525131.1
ENST00000531114.1
ENST00000355547.5
ENST00000322712.4
PDZD3
PDZ domain containing 3
chr5_+_139781393 0.19 ENST00000360839.2
ENST00000297183.6
ENST00000421134.1
ENST00000394723.3
ENST00000511151.1
ANKHD1
ankyrin repeat and KH domain containing 1
chr1_+_156096336 0.19 ENST00000504687.1
ENST00000473598.2
LMNA
lamin A/C
chr19_-_4831701 0.19 ENST00000248244.5
TICAM1
toll-like receptor adaptor molecule 1
chr15_+_40731920 0.18 ENST00000561234.1
BAHD1
bromo adjacent homology domain containing 1
chr1_-_153935791 0.18 ENST00000429040.1
SLC39A1
solute carrier family 39 (zinc transporter), member 1
chr17_+_79373540 0.18 ENST00000307745.7
RP11-1055B8.7
BAH and coiled-coil domain-containing protein 1
chr11_-_96076334 0.18 ENST00000524717.1
MAML2
mastermind-like 2 (Drosophila)
chr20_-_36156125 0.18 ENST00000397135.1
ENST00000397137.1
BLCAP
bladder cancer associated protein
chr1_-_206671061 0.18 ENST00000367119.1
C1orf147
chromosome 1 open reading frame 147
chr17_-_1419878 0.18 ENST00000449479.1
ENST00000477910.1
ENST00000542125.1
ENST00000575172.1
INPP5K
inositol polyphosphate-5-phosphatase K
chr2_-_74669009 0.18 ENST00000272430.5
RTKN
rhotekin
chr14_-_70040339 0.18 ENST00000599174.1
CCDC177
Homo sapiens coiled-coil domain containing 177 (CCDC177), mRNA.
chr2_-_240230890 0.17 ENST00000446876.1
HDAC4
histone deacetylase 4
chr1_-_153935738 0.17 ENST00000417348.1
SLC39A1
solute carrier family 39 (zinc transporter), member 1
chr3_+_9773409 0.17 ENST00000433861.2
ENST00000424362.1
ENST00000383829.2
ENST00000302054.3
ENST00000420291.1
BRPF1
bromodomain and PHD finger containing, 1
chr17_+_7590734 0.17 ENST00000457584.2
WRAP53
WD repeat containing, antisense to TP53
chr20_-_42815733 0.17 ENST00000342272.3
JPH2
junctophilin 2
chr1_-_16302565 0.17 ENST00000537142.1
ENST00000448462.2
ZBTB17
zinc finger and BTB domain containing 17

Network of associatons between targets according to the STRING database.

First level regulatory network of NFKB1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0070446 cellular response to caloric restriction(GO:0061433) negative regulation of oligodendrocyte progenitor proliferation(GO:0070446)
0.3 1.2 GO:0098582 innate vocalization behavior(GO:0098582)
0.2 1.4 GO:2001151 regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
0.2 0.9 GO:0060266 positive regulation of respiratory burst involved in inflammatory response(GO:0060265) negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.2 0.7 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2 1.1 GO:0044501 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.2 0.9 GO:1904139 mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139) positive regulation of microglial cell migration(GO:1904141)
0.2 1.1 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.2 0.5 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245) positive regulation of chondrocyte proliferation(GO:1902732) histone H3-K9 deacetylation(GO:1990619)
0.2 0.5 GO:0060738 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908) positive regulation of immature T cell proliferation in thymus(GO:0033092) right lung development(GO:0060458) primary prostatic bud elongation(GO:0060516) epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.2 0.5 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874) positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.2 0.5 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.1 1.5 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.1 0.6 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.1 0.6 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.1 0.4 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.1 1.2 GO:0021564 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025) vagus nerve development(GO:0021564)
0.1 0.6 GO:0097403 cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545)
0.1 0.4 GO:0045083 negative regulation of interleukin-12 biosynthetic process(GO:0045083)
0.1 0.6 GO:0036343 psychomotor behavior(GO:0036343)
0.1 0.4 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
0.1 0.3 GO:0090222 centrosome-templated microtubule nucleation(GO:0090222)
0.1 0.3 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.1 0.9 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.1 0.4 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.1 0.6 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.1 0.6 GO:0046449 allantoin metabolic process(GO:0000255) creatinine metabolic process(GO:0046449)
0.1 0.3 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894)
0.1 0.7 GO:0033590 response to cobalamin(GO:0033590) response to erythropoietin(GO:0036017) cellular response to erythropoietin(GO:0036018)
0.1 0.8 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.1 0.5 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.1 0.2 GO:1903093 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.1 0.9 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915) positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.1 0.5 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 0.3 GO:0060023 soft palate development(GO:0060023)
0.1 0.4 GO:1904849 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.1 0.2 GO:0051866 general adaptation syndrome(GO:0051866)
0.1 0.2 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.1 0.1 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.1 0.2 GO:0032203 telomere formation via telomerase(GO:0032203)
0.1 2.0 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 1.1 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.1 0.4 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.1 0.2 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.1 0.2 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.1 0.3 GO:2001038 regulation of cellular response to drug(GO:2001038)
0.1 0.2 GO:0018315 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.0 0.3 GO:0039689 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.0 0.1 GO:1990922 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.0 0.1 GO:2000330 positive regulation of T-helper 17 cell lineage commitment(GO:2000330)
0.0 0.1 GO:0060129 regulation of calcium-independent cell-cell adhesion(GO:0051040) thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0 0.3 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.1 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.0 0.1 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.7 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.2 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.3 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.1 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.0 0.3 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.2 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.0 0.4 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.2 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.0 0.2 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.2 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.4 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.3 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 0.3 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.3 GO:0035897 proteolysis in other organism(GO:0035897)
0.0 0.1 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.0 0.3 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.2 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.0 0.5 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.5 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.2 GO:0060263 regulation of respiratory burst(GO:0060263)
0.0 0.5 GO:2001197 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0 0.2 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.0 0.2 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.2 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.1 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.2 GO:2000828 post-embryonic body morphogenesis(GO:0040032) regulation of parathyroid hormone secretion(GO:2000828)
0.0 0.1 GO:0002636 positive regulation of germinal center formation(GO:0002636)
0.0 1.1 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.7 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:2000328 peptidyl-lysine oxidation(GO:0018057) regulation of T-helper 17 cell lineage commitment(GO:2000328) negative regulation of T-helper 17 cell lineage commitment(GO:2000329)
0.0 0.4 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.1 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.3 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.8 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.2 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.1 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.1 GO:0046967 cytosol to ER transport(GO:0046967)
0.0 0.2 GO:0045359 positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.0 0.3 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.0 0.1 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.1 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.2 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.2 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.1 GO:0060696 regulation of phospholipid catabolic process(GO:0060696)
0.0 0.4 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.4 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 0.1 GO:0002829 T-helper 1 cell lineage commitment(GO:0002296) negative regulation of type 2 immune response(GO:0002829)
0.0 0.2 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:0034670 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 0.2 GO:0071374 cellular response to parathyroid hormone stimulus(GO:0071374)
0.0 0.0 GO:0050760 thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758) negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.0 0.6 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.0 0.1 GO:0003057 regulation of the force of heart contraction by chemical signal(GO:0003057) vein smooth muscle contraction(GO:0014826)
0.0 0.0 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.2 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.2 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.3 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.2 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.0 0.1 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.0 0.3 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.1 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.0 0.1 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.3 GO:0098743 cell aggregation(GO:0098743)
0.0 0.1 GO:0072553 terminal button organization(GO:0072553)
0.0 0.4 GO:0001702 gastrulation with mouth forming second(GO:0001702)
0.0 0.1 GO:0042940 D-amino acid transport(GO:0042940)
0.0 0.0 GO:0046521 sphingoid catabolic process(GO:0046521)
0.0 0.6 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 1.5 GO:0070552 BRISC complex(GO:0070552)
0.1 0.6 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.1 0.5 GO:0031933 telomeric heterochromatin(GO:0031933)
0.1 0.3 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.1 1.4 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 0.7 GO:0043196 varicosity(GO:0043196)
0.1 0.8 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1 0.3 GO:0045160 myosin I complex(GO:0045160)
0.0 0.3 GO:0019815 B cell receptor complex(GO:0019815)
0.0 1.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.6 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.7 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.2 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 0.4 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.5 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.4 GO:0042587 glycogen granule(GO:0042587)
0.0 0.5 GO:0045180 basal cortex(GO:0045180)
0.0 0.9 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.3 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.2 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.3 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.1 GO:0035101 FACT complex(GO:0035101)
0.0 0.2 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.2 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.2 GO:0005638 lamin filament(GO:0005638)
0.0 0.2 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.3 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.5 GO:0031143 pseudopodium(GO:0031143)
0.0 0.0 GO:1990761 growth cone lamellipodium(GO:1990761)
0.0 2.7 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.1 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.1 GO:0042825 TAP complex(GO:0042825)
0.0 0.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.3 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.2 0.9 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.2 1.4 GO:0042577 lipid phosphatase activity(GO:0042577)
0.2 0.5 GO:0046969 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.1 1.5 GO:0004793 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.1 0.9 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 0.3 GO:0042019 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.1 0.6 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.1 1.4 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 0.6 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.1 0.3 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.1 0.3 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 0.8 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1 0.2 GO:0045485 omega-6 fatty acid desaturase activity(GO:0045485)
0.1 0.4 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 0.3 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 1.7 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 0.9 GO:0045159 myosin II binding(GO:0045159)
0.1 0.2 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.1 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.5 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.4 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.1 0.2 GO:0061598 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.0 0.2 GO:0052593 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.0 0.1 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.0 0.2 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.6 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.2 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.2 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 1.1 GO:0070628 proteasome binding(GO:0070628)
0.0 0.3 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.2 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.0 0.2 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.0 0.2 GO:0010851 cyclase regulator activity(GO:0010851) guanylate cyclase regulator activity(GO:0030249)
0.0 0.1 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.0 0.4 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 1.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.9 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.4 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.5 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.2 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.2 GO:0032810 sterol response element binding(GO:0032810)
0.0 0.4 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.2 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.3 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.4 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.2 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.2 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.1 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.0 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0043532 angiostatin binding(GO:0043532)
0.0 1.1 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.1 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.7 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.4 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.2 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.6 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.1 GO:0001224 RNA polymerase II transcription cofactor binding(GO:0001224) RNA polymerase II transcription coactivator binding(GO:0001225)
0.0 0.1 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 0.2 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.5 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.5 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.1 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.1 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.2 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.3 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.1 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.6 PID IL5 PATHWAY IL5-mediated signaling events
0.0 1.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.9 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.8 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.4 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.4 PID FGF PATHWAY FGF signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 1.7 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 1.1 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.4 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.6 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.8 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.6 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.1 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 0.8 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.6 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.3 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.6 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.5 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.2 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.2 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.9 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.6 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling