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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for NFE2L1

Z-value: 1.72

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Transcription factors associated with NFE2L1

Gene Symbol Gene ID Gene Info
NFE2L1
ENSG00000082641.11 nuclear factor, erythroid 2 like 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFE2L1hg19_v2_chr17_+_46131912_461319520.805.4e-02Click!

Activity profile of NFE2L1 motif

Sorted Z-values of NFE2L1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_128246769 1.72 ENST00000444226.1
MAPKAP1
mitogen-activated protein kinase associated protein 1
chr6_-_170151603 1.22 ENST00000366774.3
TCTE3
t-complex-associated-testis-expressed 3
chr2_+_159651821 1.13 ENST00000309950.3
ENST00000409042.1
DAPL1
death associated protein-like 1
chr1_-_183538319 1.12 ENST00000420553.1
ENST00000419402.1
NCF2
neutrophil cytosolic factor 2
chr11_+_63137251 1.04 ENST00000310969.4
ENST00000279178.3
SLC22A9
solute carrier family 22 (organic anion transporter), member 9
chr6_+_13272904 1.02 ENST00000379335.3
ENST00000379329.1
PHACTR1
phosphatase and actin regulator 1
chr3_-_172019686 1.00 ENST00000596321.1
AC092964.2
Uncharacterized protein
chr8_+_94752349 0.92 ENST00000391680.1
RBM12B-AS1
RBM12B antisense RNA 1
chr10_-_10504285 0.92 ENST00000602311.1
RP11-271F18.4
RP11-271F18.4
chr14_+_24779340 0.85 ENST00000533293.1
ENST00000543919.1
LTB4R2
leukotriene B4 receptor 2
chr5_+_127039075 0.82 ENST00000514853.2
CTC-228N24.1
CTC-228N24.1
chr3_-_12587055 0.81 ENST00000564146.3
C3orf83
chromosome 3 open reading frame 83
chr1_-_151319654 0.77 ENST00000430227.1
ENST00000412774.1
RFX5
regulatory factor X, 5 (influences HLA class II expression)
chr1_+_81106951 0.76 ENST00000443565.1
RP5-887A10.1
RP5-887A10.1
chr1_-_12679171 0.75 ENST00000606790.1
RP11-474O21.5
RP11-474O21.5
chr14_-_92247032 0.75 ENST00000556661.1
ENST00000553676.1
ENST00000554560.1
CATSPERB
catsper channel auxiliary subunit beta
chr3_-_27764190 0.74 ENST00000537516.1
EOMES
eomesodermin
chr17_-_77967433 0.72 ENST00000571872.1
TBC1D16
TBC1 domain family, member 16
chr8_+_22853345 0.71 ENST00000522948.1
RHOBTB2
Rho-related BTB domain containing 2
chr9_+_140083099 0.70 ENST00000322310.5
SSNA1
Sjogren syndrome nuclear autoantigen 1
chr14_+_29241910 0.68 ENST00000399387.4
ENST00000552957.1
ENST00000548213.1
C14orf23
chromosome 14 open reading frame 23
chr2_+_87755054 0.67 ENST00000423846.1
LINC00152
long intergenic non-protein coding RNA 152
chr12_-_11002063 0.66 ENST00000544994.1
ENST00000228811.4
ENST00000540107.1
PRR4
proline rich 4 (lacrimal)
chr22_+_38142235 0.65 ENST00000407319.2
ENST00000403663.2
ENST00000428075.1
TRIOBP
TRIO and F-actin binding protein
chr6_+_43027332 0.65 ENST00000347162.5
ENST00000453940.2
ENST00000479632.1
ENST00000470728.1
ENST00000458460.2
KLC4
kinesin light chain 4
chr12_+_48147699 0.65 ENST00000548498.1
SLC48A1
solute carrier family 48 (heme transporter), member 1
chr7_+_150811705 0.64 ENST00000335367.3
AGAP3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr12_-_123187890 0.64 ENST00000328880.5
HCAR2
hydroxycarboxylic acid receptor 2
chr19_-_12807422 0.63 ENST00000380339.3
ENST00000544494.1
ENST00000393261.3
FBXW9
F-box and WD repeat domain containing 9
chr16_+_31044413 0.61 ENST00000394998.1
STX4
syntaxin 4
chr7_-_34978980 0.61 ENST00000428054.1
DPY19L1
dpy-19-like 1 (C. elegans)
chr2_+_87808725 0.60 ENST00000413202.1
LINC00152
long intergenic non-protein coding RNA 152
chr9_-_34662651 0.60 ENST00000259631.4
CCL27
chemokine (C-C motif) ligand 27
chr11_+_65337901 0.58 ENST00000309328.3
ENST00000531405.1
ENST00000527920.1
ENST00000526877.1
ENST00000533115.1
ENST00000526433.1
SSSCA1
Sjogren syndrome/scleroderma autoantigen 1
chr19_-_36545649 0.57 ENST00000292894.1
THAP8
THAP domain containing 8
chr6_-_152623231 0.57 ENST00000540663.1
ENST00000537033.1
SYNE1
spectrin repeat containing, nuclear envelope 1
chr4_-_89442940 0.57 ENST00000527353.1
PIGY
phosphatidylinositol glycan anchor biosynthesis, class Y
chr11_+_126139005 0.57 ENST00000263578.5
ENST00000442061.2
ENST00000532125.1
FOXRED1
FAD-dependent oxidoreductase domain containing 1
chr4_+_139694701 0.57 ENST00000502606.1
RP11-98O2.1
RP11-98O2.1
chr18_-_2982869 0.56 ENST00000584915.1
LPIN2
lipin 2
chr2_-_98280383 0.56 ENST00000289228.5
ACTR1B
ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
chr19_+_41856816 0.55 ENST00000539627.1
TMEM91
transmembrane protein 91
chr6_+_41021027 0.55 ENST00000244669.2
APOBEC2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
chr10_-_69991865 0.55 ENST00000373673.3
ATOH7
atonal homolog 7 (Drosophila)
chr8_-_123139423 0.54 ENST00000523792.1
RP11-398G24.2
RP11-398G24.2
chr5_+_139055055 0.53 ENST00000511457.1
CXXC5
CXXC finger protein 5
chr2_-_220119280 0.53 ENST00000392088.2
TUBA4A
tubulin, alpha 4a
chr17_-_73663245 0.53 ENST00000584999.1
ENST00000317905.5
ENST00000420326.2
ENST00000340830.5
RECQL5
RecQ protein-like 5
chr6_+_131958436 0.52 ENST00000357639.3
ENST00000543135.1
ENST00000427148.2
ENST00000358229.5
ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr5_+_140248518 0.51 ENST00000398640.2
PCDHA11
protocadherin alpha 11
chr19_-_12807395 0.51 ENST00000587955.1
FBXW9
F-box and WD repeat domain containing 9
chr13_-_47471155 0.51 ENST00000543956.1
ENST00000542664.1
HTR2A
5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
chr19_-_44100275 0.51 ENST00000422989.1
ENST00000598324.1
IRGQ
immunity-related GTPase family, Q
chr3_-_47950745 0.51 ENST00000429422.1
MAP4
microtubule-associated protein 4
chr9_-_140082983 0.50 ENST00000323927.2
ANAPC2
anaphase promoting complex subunit 2
chr6_-_116447283 0.50 ENST00000452729.1
ENST00000243222.4
COL10A1
collagen, type X, alpha 1
chr5_+_139055021 0.50 ENST00000502716.1
ENST00000503511.1
CXXC5
CXXC finger protein 5
chr20_+_60174827 0.50 ENST00000543233.1
CDH4
cadherin 4, type 1, R-cadherin (retinal)
chr10_+_127661942 0.48 ENST00000417114.1
ENST00000445510.1
ENST00000368691.1
FANK1
fibronectin type III and ankyrin repeat domains 1
chr9_-_130477912 0.48 ENST00000543175.1
PTRH1
peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae)
chr22_+_30805086 0.48 ENST00000439838.1
ENST00000439023.3
RP4-539M6.19
Uncharacterized protein
chrX_+_47078069 0.48 ENST00000357227.4
ENST00000519758.1
ENST00000520893.1
ENST00000517426.1
CDK16
cyclin-dependent kinase 16
chr3_+_187957646 0.48 ENST00000457242.1
LPP
LIM domain containing preferred translocation partner in lipoma
chr6_+_159071015 0.46 ENST00000360448.3
SYTL3
synaptotagmin-like 3
chr1_+_45265897 0.46 ENST00000372201.4
PLK3
polo-like kinase 3
chr3_-_155011483 0.46 ENST00000489090.1
RP11-451G4.2
RP11-451G4.2
chr19_+_9361606 0.46 ENST00000456448.1
OR7E24
olfactory receptor, family 7, subfamily E, member 24
chr19_+_36545833 0.45 ENST00000401500.2
ENST00000270301.7
ENST00000427823.2
WDR62
WD repeat domain 62
chrX_+_107068959 0.45 ENST00000451923.1
MID2
midline 2
chr14_+_64680854 0.44 ENST00000458046.2
SYNE2
spectrin repeat containing, nuclear envelope 2
chrX_+_47077632 0.44 ENST00000457458.2
CDK16
cyclin-dependent kinase 16
chr17_-_3495644 0.44 ENST00000310522.5
ENST00000425167.2
ENST00000576351.1
TRPV1
transient receptor potential cation channel, subfamily V, member 1
chr9_-_95244781 0.44 ENST00000375544.3
ENST00000375543.1
ENST00000395538.3
ENST00000450139.2
ASPN
asporin
chr8_+_101349823 0.44 ENST00000519566.1
KB-1991G8.1
KB-1991G8.1
chr19_-_42721819 0.44 ENST00000336034.4
ENST00000598200.1
ENST00000598727.1
ENST00000596251.1
DEDD2
death effector domain containing 2
chr1_-_156265438 0.44 ENST00000362007.1
C1orf85
chromosome 1 open reading frame 85
chr7_+_872107 0.43 ENST00000405266.1
ENST00000401592.1
ENST00000403868.1
ENST00000425407.2
SUN1
Sad1 and UNC84 domain containing 1
chr9_+_131799213 0.43 ENST00000358369.4
ENST00000406926.2
ENST00000277475.5
ENST00000450073.1
FAM73B
family with sequence similarity 73, member B
chr9_+_131901710 0.43 ENST00000524946.2
PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chr7_-_7782204 0.42 ENST00000418534.2
AC007161.5
AC007161.5
chr1_-_219615984 0.42 ENST00000420762.1
RP11-95P13.1
RP11-95P13.1
chr15_+_80215113 0.42 ENST00000560255.1
C15orf37
chromosome 15 open reading frame 37
chr5_-_159797627 0.42 ENST00000393975.3
C1QTNF2
C1q and tumor necrosis factor related protein 2
chr11_+_2397418 0.42 ENST00000530648.1
CD81
CD81 molecule
chr12_+_21525818 0.42 ENST00000240652.3
ENST00000542023.1
ENST00000537593.1
IAPP
islet amyloid polypeptide
chr3_-_47934234 0.42 ENST00000420772.2
MAP4
microtubule-associated protein 4
chr19_+_18699599 0.42 ENST00000450195.2
C19orf60
chromosome 19 open reading frame 60
chr14_+_24779376 0.41 ENST00000530080.1
LTB4R2
leukotriene B4 receptor 2
chr19_+_8455077 0.41 ENST00000328024.6
RAB11B
RAB11B, member RAS oncogene family
chr1_-_151319318 0.41 ENST00000436271.1
ENST00000450506.1
ENST00000422595.1
RFX5
regulatory factor X, 5 (influences HLA class II expression)
chr17_-_73663168 0.41 ENST00000578201.1
ENST00000423245.2
RECQL5
RecQ protein-like 5
chr22_+_20861858 0.40 ENST00000414658.1
ENST00000432052.1
ENST00000425759.2
ENST00000292733.7
ENST00000542773.1
ENST00000263205.7
ENST00000406969.1
ENST00000382974.2
MED15
mediator complex subunit 15
chr10_-_123357910 0.40 ENST00000336553.6
ENST00000457416.2
ENST00000360144.3
ENST00000369059.1
ENST00000356226.4
ENST00000351936.6
FGFR2
fibroblast growth factor receptor 2
chr5_+_149877440 0.40 ENST00000518299.1
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr11_+_59522837 0.40 ENST00000437946.2
STX3
syntaxin 3
chr11_+_63742050 0.40 ENST00000314133.3
ENST00000535431.1
COX8A
AP000721.4
cytochrome c oxidase subunit VIIIA (ubiquitous)
Uncharacterized protein
chr6_-_3157760 0.40 ENST00000333628.3
TUBB2A
tubulin, beta 2A class IIa
chr11_+_64052294 0.40 ENST00000536667.1
GPR137
G protein-coupled receptor 137
chr2_-_161056762 0.39 ENST00000428609.2
ENST00000409967.2
ITGB6
integrin, beta 6
chr2_+_87754989 0.39 ENST00000409898.2
ENST00000419680.2
ENST00000414584.1
ENST00000455131.1
LINC00152
long intergenic non-protein coding RNA 152
chr14_-_69262947 0.39 ENST00000557086.1
ZFP36L1
ZFP36 ring finger protein-like 1
chr1_+_28586006 0.39 ENST00000253063.3
SESN2
sestrin 2
chr3_+_33331156 0.39 ENST00000542085.1
FBXL2
F-box and leucine-rich repeat protein 2
chr3_-_118753792 0.39 ENST00000480431.1
IGSF11
immunoglobulin superfamily, member 11
chr6_+_155585147 0.38 ENST00000367165.3
CLDN20
claudin 20
chr22_-_39928823 0.38 ENST00000334678.3
RPS19BP1
ribosomal protein S19 binding protein 1
chr16_+_3068393 0.38 ENST00000573001.1
TNFRSF12A
tumor necrosis factor receptor superfamily, member 12A
chr6_+_168434678 0.38 ENST00000496008.1
KIF25
kinesin family member 25
chr9_+_134065519 0.38 ENST00000531600.1
NUP214
nucleoporin 214kDa
chr18_+_11752783 0.38 ENST00000585642.1
GNAL
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr11_+_59480899 0.38 ENST00000300150.7
STX3
syntaxin 3
chr10_+_121410882 0.38 ENST00000369085.3
BAG3
BCL2-associated athanogene 3
chr4_+_185734773 0.38 ENST00000508020.1
RP11-701P16.2
Uncharacterized protein
chr20_-_33539655 0.37 ENST00000451957.2
GSS
glutathione synthetase
chr16_+_57662596 0.36 ENST00000567397.1
ENST00000568979.1
GPR56
G protein-coupled receptor 56
chr19_-_47616992 0.36 ENST00000253048.5
ZC3H4
zinc finger CCCH-type containing 4
chrX_+_53123314 0.36 ENST00000605526.1
ENST00000604062.1
ENST00000604369.1
ENST00000366185.2
ENST00000604849.1
RP11-258C19.5
long intergenic non-protein coding RNA 1155
chr11_+_35211511 0.36 ENST00000524922.1
CD44
CD44 molecule (Indian blood group)
chr1_+_159750776 0.36 ENST00000368107.1
DUSP23
dual specificity phosphatase 23
chr9_+_134065506 0.35 ENST00000483497.2
NUP214
nucleoporin 214kDa
chr7_+_149571045 0.35 ENST00000479613.1
ENST00000606024.1
ENST00000464662.1
ENST00000425642.2
ATP6V0E2
ATPase, H+ transporting V0 subunit e2
chr12_-_91573132 0.35 ENST00000550563.1
ENST00000546370.1
DCN
decorin
chr1_-_151319283 0.35 ENST00000392746.3
RFX5
regulatory factor X, 5 (influences HLA class II expression)
chr9_+_125027127 0.35 ENST00000441707.1
ENST00000373723.5
ENST00000373729.1
MRRF
mitochondrial ribosome recycling factor
chr1_+_43613566 0.35 ENST00000409396.1
FAM183A
family with sequence similarity 183, member A
chr6_-_31107127 0.35 ENST00000259845.4
PSORS1C2
psoriasis susceptibility 1 candidate 2
chr21_-_47738112 0.35 ENST00000417060.1
C21orf58
chromosome 21 open reading frame 58
chr6_-_44400720 0.34 ENST00000595057.1
AL133262.1
AL133262.1
chr9_-_100684769 0.34 ENST00000455506.1
ENST00000375117.4
C9orf156
chromosome 9 open reading frame 156
chr10_-_49860525 0.34 ENST00000435790.2
ARHGAP22
Rho GTPase activating protein 22
chr14_-_24768913 0.34 ENST00000288111.7
DHRS1
dehydrogenase/reductase (SDR family) member 1
chr1_-_23520755 0.34 ENST00000314113.3
HTR1D
5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
chr11_+_64052266 0.34 ENST00000539851.1
GPR137
G protein-coupled receptor 137
chr2_-_219524193 0.33 ENST00000450560.1
ENST00000449707.1
ENST00000432460.1
ENST00000411696.2
ZNF142
zinc finger protein 142
chr8_+_55466915 0.33 ENST00000522711.2
RP11-53M11.3
RP11-53M11.3
chr22_+_20862321 0.33 ENST00000541476.1
ENST00000438962.1
MED15
mediator complex subunit 15
chr19_-_45681482 0.33 ENST00000592647.1
ENST00000006275.4
ENST00000588062.1
ENST00000585934.1
TRAPPC6A
trafficking protein particle complex 6A
chr16_+_57662419 0.33 ENST00000388812.4
ENST00000538815.1
ENST00000456916.1
ENST00000567154.1
ENST00000388813.5
ENST00000562558.1
ENST00000566271.2
GPR56
G protein-coupled receptor 56
chr2_+_29001711 0.33 ENST00000418910.1
PPP1CB
protein phosphatase 1, catalytic subunit, beta isozyme
chr1_-_154178803 0.33 ENST00000368525.3
C1orf189
chromosome 1 open reading frame 189
chrX_-_48814810 0.33 ENST00000376488.3
ENST00000396743.3
ENST00000156084.4
OTUD5
OTU domain containing 5
chr2_-_161056802 0.33 ENST00000283249.2
ENST00000409872.1
ITGB6
integrin, beta 6
chr3_-_114790179 0.33 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr16_+_31044812 0.33 ENST00000313843.3
STX4
syntaxin 4
chr1_+_159750720 0.32 ENST00000368109.1
ENST00000368108.3
DUSP23
dual specificity phosphatase 23
chrX_+_47077680 0.32 ENST00000522883.1
CDK16
cyclin-dependent kinase 16
chr17_-_6524159 0.32 ENST00000589033.1
KIAA0753
KIAA0753
chr16_+_29819372 0.32 ENST00000568544.1
ENST00000569978.1
MAZ
MYC-associated zinc finger protein (purine-binding transcription factor)
chrX_+_15767971 0.32 ENST00000479740.1
ENST00000454127.2
CA5B
carbonic anhydrase VB, mitochondrial
chr7_+_871559 0.32 ENST00000421580.1
SUN1
Sad1 and UNC84 domain containing 1
chr1_+_206516200 0.32 ENST00000295713.5
SRGAP2
SLIT-ROBO Rho GTPase activating protein 2
chr9_-_39239171 0.32 ENST00000358144.2
CNTNAP3
contactin associated protein-like 3
chr22_-_39097527 0.32 ENST00000417712.1
JOSD1
Josephin domain containing 1
chr9_-_97356075 0.31 ENST00000375337.3
FBP2
fructose-1,6-bisphosphatase 2
chr6_-_31940065 0.31 ENST00000375349.3
ENST00000337523.5
DXO
decapping exoribonuclease
chr4_+_8442496 0.31 ENST00000389737.4
ENST00000504134.1
TRMT44
tRNA methyltransferase 44 homolog (S. cerevisiae)
chr5_-_176936844 0.31 ENST00000510380.1
ENST00000510898.1
ENST00000357198.4
DOK3
docking protein 3
chr5_+_173763250 0.31 ENST00000515513.1
ENST00000507361.1
ENST00000510234.1
RP11-267A15.1
RP11-267A15.1
chr11_+_65154070 0.31 ENST00000317568.5
ENST00000531296.1
ENST00000533782.1
ENST00000355991.5
ENST00000416776.2
ENST00000526201.1
FRMD8
FERM domain containing 8
chr1_-_94312706 0.31 ENST00000370244.1
BCAR3
breast cancer anti-estrogen resistance 3
chr17_+_42264395 0.31 ENST00000587989.1
ENST00000590235.1
TMUB2
transmembrane and ubiquitin-like domain containing 2
chr16_+_2286726 0.31 ENST00000382437.4
ENST00000569184.1
DNASE1L2
deoxyribonuclease I-like 2
chr1_-_106161540 0.31 ENST00000420901.1
ENST00000610126.1
ENST00000435253.2
RP11-251P6.1
RP11-251P6.1
chr11_+_64052454 0.31 ENST00000539833.1
GPR137
G protein-coupled receptor 137
chr1_-_198906528 0.31 ENST00000432296.1
MIR181A1HG
MIR181A1 host gene (non-protein coding)
chr1_+_67632083 0.31 ENST00000347310.5
ENST00000371002.1
IL23R
interleukin 23 receptor
chr3_-_49142504 0.31 ENST00000306125.6
ENST00000420147.2
QARS
glutaminyl-tRNA synthetase
chr3_-_105588231 0.30 ENST00000545639.1
ENST00000394027.3
ENST00000438603.1
ENST00000447441.1
ENST00000443752.1
CBLB
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr4_+_3344141 0.30 ENST00000306648.7
RGS12
regulator of G-protein signaling 12
chr6_+_63921399 0.30 ENST00000356170.3
FKBP1C
FK506 binding protein 1C
chr17_-_26220366 0.30 ENST00000460380.2
ENST00000508862.1
ENST00000379102.3
ENST00000582441.1
LYRM9
RP1-66C13.4
LYR motif containing 9
Uncharacterized protein
chr1_-_151319710 0.30 ENST00000290524.4
ENST00000437327.1
ENST00000452513.2
ENST00000368870.2
ENST00000452671.2
RFX5
regulatory factor X, 5 (influences HLA class II expression)
chr20_-_35274548 0.30 ENST00000262866.4
SLA2
Src-like-adaptor 2
chr10_-_23003460 0.30 ENST00000376573.4
PIP4K2A
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
chr3_-_52488048 0.30 ENST00000232975.3
TNNC1
troponin C type 1 (slow)
chr15_-_54267147 0.30 ENST00000558866.1
ENST00000558920.1
RP11-643A5.2
RP11-643A5.2
chrX_+_49126294 0.29 ENST00000466508.1
ENST00000438316.1
ENST00000055335.6
ENST00000495799.1
PPP1R3F
protein phosphatase 1, regulatory subunit 3F
chr14_-_95942173 0.29 ENST00000334258.5
ENST00000557275.1
ENST00000553340.1
SYNE3
spectrin repeat containing, nuclear envelope family member 3
chr1_+_100435986 0.29 ENST00000532693.1
SLC35A3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
chr1_+_17914907 0.29 ENST00000375420.3
ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr3_-_49142178 0.29 ENST00000452739.1
ENST00000414533.1
ENST00000417025.1
QARS
glutaminyl-tRNA synthetase
chr3_-_120365866 0.29 ENST00000475447.2
HGD
homogentisate 1,2-dioxygenase
chr1_+_112938803 0.29 ENST00000271277.6
CTTNBP2NL
CTTNBP2 N-terminal like
chr19_+_11546093 0.28 ENST00000591462.1
PRKCSH
protein kinase C substrate 80K-H
chr18_+_72166564 0.28 ENST00000583216.1
ENST00000581912.1
ENST00000582589.1
CNDP2
CNDP dipeptidase 2 (metallopeptidase M20 family)
chrX_-_148713440 0.28 ENST00000536359.1
ENST00000316916.8
TMEM185A
transmembrane protein 185A
chr2_-_68547061 0.28 ENST00000263655.3
CNRIP1
cannabinoid receptor interacting protein 1
chr19_+_40477062 0.28 ENST00000455878.2
PSMC4
proteasome (prosome, macropain) 26S subunit, ATPase, 4
chr20_+_44563267 0.28 ENST00000372409.3
PCIF1
PDX1 C-terminal inhibiting factor 1
chr3_+_112929850 0.28 ENST00000464546.1
BOC
BOC cell adhesion associated, oncogene regulated
chr1_+_154966058 0.27 ENST00000392487.1
LENEP
lens epithelial protein
chr17_-_71223839 0.27 ENST00000579872.1
ENST00000580032.1
FAM104A
family with sequence similarity 104, member A
chr16_-_75301886 0.27 ENST00000393422.2
BCAR1
breast cancer anti-estrogen resistance 1
chr19_+_44100727 0.27 ENST00000528387.1
ENST00000529930.1
ENST00000336564.4
ENST00000607544.1
ENST00000526798.1
ZNF576
SRRM5
zinc finger protein 576
serine/arginine repetitive matrix 5
chr1_-_158656488 0.27 ENST00000368147.4
SPTA1
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr2_+_74685413 0.27 ENST00000233615.2
WBP1
WW domain binding protein 1
chr1_+_62439037 0.26 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr20_+_327413 0.26 ENST00000609179.1
NRSN2
neurensin 2
chr1_+_11866270 0.26 ENST00000376497.3
ENST00000376487.3
ENST00000376496.3
CLCN6
chloride channel, voltage-sensitive 6
chr3_+_47422485 0.26 ENST00000431726.1
ENST00000456221.1
ENST00000265562.4
PTPN23
protein tyrosine phosphatase, non-receptor type 23

Network of associatons between targets according to the STRING database.

First level regulatory network of NFE2L1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.3 0.9 GO:0043309 regulation of eosinophil degranulation(GO:0043309) positive regulation of eosinophil degranulation(GO:0043311) regulation of eosinophil activation(GO:1902566) positive regulation of eosinophil activation(GO:1902568)
0.2 1.7 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.2 1.2 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.2 0.6 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.2 0.5 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.2 0.5 GO:0060915 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow(GO:0035602) fibroblast growth factor receptor signaling pathway involved in hemopoiesis(GO:0035603) fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow(GO:0035604) fibroblast growth factor receptor signaling pathway involved in mammary gland specification(GO:0060595) mammary gland bud formation(GO:0060615) branch elongation involved in salivary gland morphogenesis(GO:0060667) mesenchymal cell differentiation involved in lung development(GO:0060915)
0.2 0.5 GO:0007113 endomitotic cell cycle(GO:0007113)
0.1 0.4 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.1 1.0 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.7 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.1 1.0 GO:0015747 urate transport(GO:0015747)
0.1 0.5 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.1 0.7 GO:0060809 mesodermal to mesenchymal transition involved in gastrulation(GO:0060809)
0.1 0.4 GO:0050960 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.1 0.6 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.1 0.3 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.1 0.3 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.1 0.4 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 1.2 GO:0030473 nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration(GO:0021817) nuclear migration along microtubule(GO:0030473)
0.1 0.4 GO:1901804 beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.1 0.4 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.1 0.3 GO:1903248 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.1 0.6 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 0.3 GO:0003363 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.1 0.9 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.2 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.1 0.4 GO:0097403 cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545)
0.1 0.8 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.1 0.3 GO:0003335 corneocyte development(GO:0003335)
0.1 0.2 GO:0006533 aspartate catabolic process(GO:0006533)
0.1 0.3 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.1 0.2 GO:0090427 activation of meiosis(GO:0090427)
0.1 0.2 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.1 0.4 GO:0043128 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.1 0.3 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.1 0.3 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.1 0.7 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.1 0.4 GO:1903232 melanosome assembly(GO:1903232)
0.1 0.2 GO:0019860 uracil metabolic process(GO:0019860)
0.1 0.2 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.1 0.4 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 0.2 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
0.1 0.4 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.1 0.4 GO:0039689 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.1 0.2 GO:0014054 positive regulation of gamma-aminobutyric acid secretion(GO:0014054) NAD transport(GO:0043132)
0.1 0.2 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.1 0.2 GO:0018315 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.1 0.1 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.1 0.4 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.1 0.3 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.1 0.2 GO:1902856 negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.1 0.3 GO:0098502 DNA dephosphorylation(GO:0098502)
0.1 0.4 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1 0.2 GO:1903979 negative regulation of microglial cell activation(GO:1903979)
0.1 0.4 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.1 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.3 GO:0030047 actin modification(GO:0030047)
0.0 0.1 GO:0021814 cell motility involved in cerebral cortex radial glia guided migration(GO:0021814)
0.0 0.1 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713) cellular response to folic acid(GO:0071231)
0.0 0.3 GO:0055095 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.0 0.3 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.0 0.1 GO:0072737 response to diamide(GO:0072737) cellular response to diamide(GO:0072738)
0.0 0.2 GO:1903978 regulation of microglial cell activation(GO:1903978)
0.0 0.1 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002586)
0.0 0.3 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.2 GO:0045906 negative regulation of vasoconstriction(GO:0045906) regulation of G-protein coupled receptor internalization(GO:1904020)
0.0 0.4 GO:0018317 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.3 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.0 0.2 GO:0060578 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.0 0.3 GO:0014827 intestine smooth muscle contraction(GO:0014827)
0.0 0.2 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.3 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.4 GO:1904379 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.4 GO:0016075 rRNA catabolic process(GO:0016075)
0.0 0.3 GO:2000295 regulation of hydrogen peroxide catabolic process(GO:2000295)
0.0 0.6 GO:0015886 heme transport(GO:0015886)
0.0 0.2 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 0.4 GO:0045054 constitutive secretory pathway(GO:0045054)
0.0 0.6 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.4 GO:0006477 protein sulfation(GO:0006477)
0.0 0.2 GO:0019303 D-ribose catabolic process(GO:0019303)
0.0 1.1 GO:0045730 respiratory burst(GO:0045730)
0.0 0.3 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:0043308 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil activation(GO:0043307) eosinophil degranulation(GO:0043308)
0.0 0.1 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.0 0.4 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.4 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.2 GO:0090166 Golgi disassembly(GO:0090166)
0.0 0.3 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.2 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.5 GO:0021554 optic nerve development(GO:0021554)
0.0 0.4 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.5 GO:0071028 nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0 0.9 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.2 GO:0061141 lung ciliated cell differentiation(GO:0061141)
0.0 0.3 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.0 0.2 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.2 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.1 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.5 GO:0060326 cell chemotaxis(GO:0060326)
0.0 1.0 GO:0005979 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.0 0.3 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.7 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 1.1 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.0 0.5 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.2 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.3 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.6 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.7 GO:0090383 phagosome acidification(GO:0090383)
0.0 0.1 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.0 1.0 GO:0007099 centriole replication(GO:0007099)
0.0 0.6 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.1 GO:0042256 mature ribosome assembly(GO:0042256)
0.0 0.1 GO:0007249 I-kappaB kinase/NF-kappaB signaling(GO:0007249)
0.0 0.2 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.3 GO:0050849 negative regulation of calcium-mediated signaling(GO:0050849)
0.0 0.2 GO:0030091 protein repair(GO:0030091)
0.0 0.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.0 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 0.5 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.2 GO:0071670 smooth muscle cell chemotaxis(GO:0071670)
0.0 0.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.8 GO:0001919 regulation of receptor recycling(GO:0001919)
0.0 0.1 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.4 GO:0071625 vocalization behavior(GO:0071625)
0.0 0.4 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.0 0.1 GO:0009597 detection of virus(GO:0009597)
0.0 0.2 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.5 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.6 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.1 GO:0003383 apical constriction(GO:0003383)
0.0 0.2 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.0 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.0 GO:0014901 regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
0.0 0.1 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.1 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.0 0.4 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.1 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.0 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.2 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.1 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0 0.3 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.1 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.2 GO:0097264 self proteolysis(GO:0097264)
0.0 0.3 GO:0001946 lymphangiogenesis(GO:0001946)
0.0 0.4 GO:0036507 protein demannosylation(GO:0036507) protein alpha-1,2-demannosylation(GO:0036508) endoplasmic reticulum mannose trimming(GO:1904380)
0.0 0.2 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.2 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.4 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.2 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.2 0.8 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.1 0.7 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.1 1.1 GO:0032010 phagolysosome(GO:0032010)
0.1 0.3 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.1 0.3 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.7 GO:0036128 CatSper complex(GO:0036128)
0.1 0.2 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 2.1 GO:0031932 TORC2 complex(GO:0031932)
0.1 2.1 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.2 GO:0001534 radial spoke(GO:0001534)
0.1 0.2 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.1 0.9 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.1 0.2 GO:0033186 CAF-1 complex(GO:0033186)
0.1 0.5 GO:0070852 cell body fiber(GO:0070852)
0.1 0.3 GO:0043209 myelin sheath(GO:0043209)
0.1 0.4 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.2 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.3 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.2 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 0.2 GO:0097513 myosin II filament(GO:0097513)
0.0 0.6 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.5 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.6 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.3 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.2 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.2 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 0.3 GO:0032437 cuticular plate(GO:0032437)
0.0 0.3 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0 0.5 GO:0005869 dynactin complex(GO:0005869)
0.0 0.4 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.2 GO:0097452 GAIT complex(GO:0097452)
0.0 0.1 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.6 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.1 GO:0031045 dense core granule(GO:0031045)
0.0 0.1 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.8 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 0.1 GO:0031673 H zone(GO:0031673)
0.0 0.3 GO:0042587 glycogen granule(GO:0042587)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.3 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 1.2 GO:0030286 dynein complex(GO:0030286)
0.0 0.3 GO:0042584 chromaffin granule membrane(GO:0042584)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.3 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.3 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.9 GO:0016592 mediator complex(GO:0016592)
0.0 0.4 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.5 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.4 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.0 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.0 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.2 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.3 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 0.2 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0004974 leukotriene B4 receptor activity(GO:0001632) leukotriene receptor activity(GO:0004974)
0.2 0.9 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.2 0.6 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.2 0.5 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.1 0.6 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.1 1.2 GO:0009378 four-way junction helicase activity(GO:0009378)
0.1 1.0 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 0.4 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.1 0.5 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.1 0.3 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.1 0.3 GO:0042020 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.1 0.9 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1 0.6 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.3 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155)
0.1 0.3 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.1 0.3 GO:0030492 hemoglobin binding(GO:0030492)
0.1 0.3 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.1 0.8 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 0.3 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.4 GO:0004348 glucosylceramidase activity(GO:0004348)
0.1 0.6 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.3 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.1 0.2 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.1 0.3 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.1 0.3 GO:0051734 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.1 0.5 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.1 1.1 GO:0016176 superoxide-generating NADPH oxidase activity(GO:0016175) superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.4 GO:0031013 troponin I binding(GO:0031013)
0.1 0.4 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 0.2 GO:0070364 mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.1 1.1 GO:0070513 death domain binding(GO:0070513)
0.1 0.2 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 0.3 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.2 GO:0061598 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.1 0.3 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.1 0.4 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.1 0.4 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.1 0.2 GO:0019862 IgA binding(GO:0019862)
0.1 1.7 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.3 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.2 GO:0080130 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.1 0.7 GO:0045159 myosin II binding(GO:0045159)
0.0 0.6 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.1 GO:0061714 folic acid receptor activity(GO:0061714)
0.0 0.2 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.5 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.2 GO:0019976 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.0 0.7 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.5 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.3 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.1 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.0 0.6 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.2 GO:0004936 alpha-adrenergic receptor activity(GO:0004936)
0.0 0.4 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.2 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.2 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 1.3 GO:0005521 lamin binding(GO:0005521)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 1.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.0 0.1 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.0 0.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.2 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.4 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.4 GO:0016594 glycine binding(GO:0016594)
0.0 0.1 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.6 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.5 GO:0036442 hydrogen-exporting ATPase activity(GO:0036442) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.1 GO:0003955 NAD(P)H dehydrogenase (quinone) activity(GO:0003955)
0.0 0.1 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.0 0.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.4 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.2 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.6 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.2 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.4 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.2 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 0.4 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 1.0 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.2 GO:0005542 folic acid binding(GO:0005542)
0.0 0.2 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.5 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.4 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.4 GO:0031489 myosin V binding(GO:0031489)
0.0 0.4 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.1 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 2.0 GO:0003774 motor activity(GO:0003774)
0.0 0.0 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.1 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.8 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.8 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.7 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.7 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.5 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.3 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.2 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.4 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 1.3 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.1 2.1 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.7 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 1.2 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.5 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.0 1.3 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.4 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.4 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.6 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.6 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.2 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.4 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.4 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.4 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.3 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.5 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.4 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.2 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis