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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for NFATC2_NFATC3

Z-value: 1.21

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Transcription factors associated with NFATC2_NFATC3

Gene Symbol Gene ID Gene Info
NFATC2
ENSG00000101096.15 nuclear factor of activated T cells 2
NFATC3
ENSG00000072736.14 nuclear factor of activated T cells 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFATC3hg19_v2_chr16_+_68119440_681195610.671.5e-01Click!
NFATC2hg19_v2_chr20_-_50179368_501793920.167.7e-01Click!

Activity profile of NFATC2_NFATC3 motif

Sorted Z-values of NFATC2_NFATC3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_-_85969774 1.76 ENST00000598933.1
RP11-542M13.3
RP11-542M13.3
chr2_+_20650796 1.42 ENST00000448241.1
AC023137.2
AC023137.2
chrX_-_15683147 1.14 ENST00000380342.3
TMEM27
transmembrane protein 27
chr6_+_148593425 0.87 ENST00000367469.1
SASH1
SAM and SH3 domain containing 1
chr6_-_13290684 0.80 ENST00000606393.1
RP1-257A7.5
RP1-257A7.5
chr14_+_32476072 0.76 ENST00000556949.1
RP11-187E13.2
Uncharacterized protein
chrX_+_152683780 0.65 ENST00000338647.5
ZFP92
ZFP92 zinc finger protein
chr19_+_36346734 0.63 ENST00000586102.3
KIRREL2
kin of IRRE like 2 (Drosophila)
chr5_+_35852797 0.62 ENST00000508941.1
IL7R
interleukin 7 receptor
chr17_+_6900201 0.55 ENST00000480801.1
ALOX12
arachidonate 12-lipoxygenase
chr5_-_111093759 0.54 ENST00000509979.1
ENST00000513100.1
ENST00000508161.1
ENST00000455559.2
NREP
neuronal regeneration related protein
chr14_-_51863853 0.53 ENST00000556762.1
RP11-255G12.3
RP11-255G12.3
chr10_-_16563870 0.53 ENST00000298943.3
C1QL3
complement component 1, q subcomponent-like 3
chr1_+_209941942 0.52 ENST00000487271.1
ENST00000477431.1
TRAF3IP3
TRAF3 interacting protein 3
chr6_+_144665237 0.50 ENST00000421035.2
UTRN
utrophin
chr6_+_26183958 0.47 ENST00000356530.3
HIST1H2BE
histone cluster 1, H2be
chr5_-_78808617 0.47 ENST00000282260.6
ENST00000508576.1
ENST00000535690.1
HOMER1
homer homolog 1 (Drosophila)
chr3_-_111852061 0.44 ENST00000488580.1
ENST00000460387.2
ENST00000484193.1
ENST00000487901.1
GCSAM
germinal center-associated, signaling and motility
chr14_-_77889860 0.42 ENST00000555603.1
NOXRED1
NADP-dependent oxidoreductase domain containing 1
chr17_-_15469590 0.42 ENST00000312127.2
CDRT1
CMT duplicated region transcript 1; Uncharacterized protein
chr6_+_31105426 0.41 ENST00000547221.1
PSORS1C1
psoriasis susceptibility 1 candidate 1
chr2_+_120517717 0.41 ENST00000420482.1
ENST00000488279.2
PTPN4
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr9_+_35806082 0.40 ENST00000447210.1
NPR2
natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
chr17_+_44701402 0.40 ENST00000575068.1
NSF
N-ethylmaleimide-sensitive factor
chr7_-_139756791 0.39 ENST00000489809.1
PARP12
poly (ADP-ribose) polymerase family, member 12
chr12_-_109747023 0.38 ENST00000355216.1
ENST00000299162.5
FOXN4
forkhead box N4
chr7_+_28452130 0.38 ENST00000357727.2
CREB5
cAMP responsive element binding protein 5
chr15_+_93443419 0.37 ENST00000557381.1
ENST00000420239.2
CHD2
chromodomain helicase DNA binding protein 2
chr5_+_140480083 0.37 ENST00000231130.2
PCDHB3
protocadherin beta 3
chr15_+_84841242 0.37 ENST00000558195.1
RP11-182J1.16
ubiquitin-conjugating enzyme E2Q family member 2-like
chr5_-_108063949 0.36 ENST00000606054.1
LINC01023
long intergenic non-protein coding RNA 1023
chr22_-_28490123 0.35 ENST00000442232.1
TTC28
tetratricopeptide repeat domain 28
chr1_-_151319318 0.35 ENST00000436271.1
ENST00000450506.1
ENST00000422595.1
RFX5
regulatory factor X, 5 (influences HLA class II expression)
chr20_+_62369623 0.35 ENST00000467211.1
RP4-583P15.14
RP4-583P15.14
chr5_+_131993856 0.35 ENST00000304506.3
IL13
interleukin 13
chr11_+_101983176 0.34 ENST00000524575.1
YAP1
Yes-associated protein 1
chr9_-_13165457 0.34 ENST00000542239.1
ENST00000538841.1
ENST00000433359.2
MPDZ
multiple PDZ domain protein
chr6_+_106535455 0.34 ENST00000424894.1
PRDM1
PR domain containing 1, with ZNF domain
chr3_+_69812877 0.33 ENST00000457080.1
ENST00000328528.6
MITF
microphthalmia-associated transcription factor
chr3_-_161089289 0.33 ENST00000497137.1
SPTSSB
serine palmitoyltransferase, small subunit B
chr11_-_75062730 0.33 ENST00000420843.2
ENST00000360025.3
ARRB1
arrestin, beta 1
chr1_+_36038971 0.33 ENST00000373235.3
TFAP2E
transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon)
chr9_-_73483926 0.33 ENST00000396283.1
ENST00000361823.5
TRPM3
transient receptor potential cation channel, subfamily M, member 3
chr22_+_45680822 0.32 ENST00000216211.4
ENST00000396082.2
UPK3A
uroplakin 3A
chr16_+_86612112 0.32 ENST00000320241.3
FOXL1
forkhead box L1
chr13_-_46716969 0.32 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr12_+_6554021 0.32 ENST00000266557.3
CD27
CD27 molecule
chr18_-_33047039 0.32 ENST00000591141.1
ENST00000586741.1
RP11-322E11.5
RP11-322E11.5
chr9_+_129097520 0.31 ENST00000436593.3
MVB12B
multivesicular body subunit 12B
chr12_-_52585765 0.31 ENST00000313234.5
ENST00000394815.2
KRT80
keratin 80
chr6_+_31916733 0.30 ENST00000483004.1
CFB
complement factor B
chrX_+_133941218 0.30 ENST00000370784.4
ENST00000370785.3
FAM122C
family with sequence similarity 122C
chr11_-_75062829 0.30 ENST00000393505.4
ARRB1
arrestin, beta 1
chr1_+_81106951 0.29 ENST00000443565.1
RP5-887A10.1
RP5-887A10.1
chr6_+_138188351 0.29 ENST00000421450.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr7_-_41742697 0.29 ENST00000242208.4
INHBA
inhibin, beta A
chr17_-_28661065 0.29 ENST00000328886.4
ENST00000538566.2
TMIGD1
transmembrane and immunoglobulin domain containing 1
chr14_-_76447336 0.29 ENST00000556285.1
TGFB3
transforming growth factor, beta 3
chr6_-_15586238 0.28 ENST00000462989.2
DTNBP1
dystrobrevin binding protein 1
chr11_-_57089774 0.28 ENST00000527207.1
TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chr2_+_198570081 0.27 ENST00000282276.6
MARS2
methionyl-tRNA synthetase 2, mitochondrial
chr15_-_44069513 0.27 ENST00000433927.1
ELL3
elongation factor RNA polymerase II-like 3
chr18_+_43405471 0.27 ENST00000389474.3
SIGLEC15
sialic acid binding Ig-like lectin 15
chr2_+_177028805 0.27 ENST00000249440.3
HOXD3
homeobox D3
chr6_+_41021027 0.27 ENST00000244669.2
APOBEC2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
chr2_+_234580499 0.26 ENST00000354728.4
UGT1A9
UDP glucuronosyltransferase 1 family, polypeptide A9
chr2_-_40657397 0.26 ENST00000408028.2
ENST00000332839.4
ENST00000406391.2
ENST00000542024.1
ENST00000542756.1
ENST00000405901.3
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr6_-_136788001 0.26 ENST00000544465.1
MAP7
microtubule-associated protein 7
chr12_+_79357815 0.26 ENST00000547046.1
SYT1
synaptotagmin I
chr3_-_195310802 0.26 ENST00000421243.1
ENST00000453131.1
APOD
apolipoprotein D
chr14_-_54418598 0.26 ENST00000609748.1
ENST00000558961.1
BMP4
bone morphogenetic protein 4
chr12_-_88423164 0.26 ENST00000298699.2
ENST00000550553.1
C12orf50
chromosome 12 open reading frame 50
chr5_+_61708488 0.25 ENST00000505902.1
IPO11
importin 11
chr14_+_77582905 0.25 ENST00000557408.1
TMEM63C
transmembrane protein 63C
chr5_-_124081008 0.25 ENST00000306315.5
ZNF608
zinc finger protein 608
chr9_+_19049372 0.25 ENST00000380527.1
RRAGA
Ras-related GTP binding A
chr6_-_30685214 0.25 ENST00000425072.1
MDC1
mediator of DNA-damage checkpoint 1
chr9_-_136283156 0.25 ENST00000371942.3
REXO4
REX4, RNA exonuclease 4 homolog (S. cerevisiae)
chr14_-_23479331 0.24 ENST00000397377.1
ENST00000397379.3
ENST00000406429.2
ENST00000341470.4
ENST00000555998.1
ENST00000397376.2
ENST00000553675.1
ENST00000553931.1
ENST00000555575.1
ENST00000553958.1
ENST00000555098.1
ENST00000556419.1
ENST00000553606.1
ENST00000299088.6
ENST00000554179.1
ENST00000397382.4
C14orf93
chromosome 14 open reading frame 93
chr4_-_184243561 0.24 ENST00000514470.1
ENST00000541814.1
CLDN24
claudin 24
chr17_+_79953310 0.24 ENST00000582355.2
ASPSCR1
alveolar soft part sarcoma chromosome region, candidate 1
chr16_-_10868853 0.24 ENST00000572428.1
TVP23A
trans-golgi network vesicle protein 23 homolog A (S. cerevisiae)
chrX_-_154255143 0.23 ENST00000453950.1
ENST00000423959.1
F8
coagulation factor VIII, procoagulant component
chr2_+_232316906 0.23 ENST00000370380.2
AC017104.2
Uncharacterized protein
chr5_+_74011328 0.23 ENST00000513336.1
HEXB
hexosaminidase B (beta polypeptide)
chr18_-_24237339 0.23 ENST00000580191.1
KCTD1
potassium channel tetramerization domain containing 1
chr11_+_18417948 0.23 ENST00000542179.1
LDHA
lactate dehydrogenase A
chr2_-_190044480 0.23 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr4_-_140477353 0.22 ENST00000406354.1
ENST00000506866.2
SETD7
SET domain containing (lysine methyltransferase) 7
chr7_-_111424462 0.22 ENST00000437129.1
DOCK4
dedicator of cytokinesis 4
chr14_+_77642191 0.22 ENST00000555338.1
ENST00000556514.1
TMEM63C
transmembrane protein 63C
chr1_+_247579451 0.22 ENST00000391828.3
ENST00000366497.2
NLRP3
NLR family, pyrin domain containing 3
chr6_-_10415218 0.22 ENST00000466073.1
ENST00000498450.1
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr5_-_64777685 0.22 ENST00000536360.1
ADAMTS6
ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr15_+_96869165 0.22 ENST00000421109.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr11_-_119293903 0.21 ENST00000580275.1
THY1
Thy-1 cell surface antigen
chr8_-_13134045 0.21 ENST00000512044.2
DLC1
deleted in liver cancer 1
chr2_+_234580525 0.21 ENST00000609637.1
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A8
chr1_+_239882842 0.21 ENST00000448020.1
CHRM3
cholinergic receptor, muscarinic 3
chr17_+_59477233 0.21 ENST00000240328.3
TBX2
T-box 2
chr17_-_39041479 0.21 ENST00000167588.3
KRT20
keratin 20
chr5_-_131879205 0.21 ENST00000231454.1
IL5
interleukin 5 (colony-stimulating factor, eosinophil)
chr11_+_34663913 0.21 ENST00000532302.1
EHF
ets homologous factor
chr14_+_38065052 0.21 ENST00000556845.1
TTC6
tetratricopeptide repeat domain 6
chr17_-_15522826 0.21 ENST00000395906.3
CDRT1
CMT1A duplicated region transcript 1
chr12_-_67197760 0.21 ENST00000539540.1
ENST00000540433.1
ENST00000541947.1
ENST00000538373.1
GRIP1
glutamate receptor interacting protein 1
chr11_-_123065989 0.21 ENST00000448775.2
CLMP
CXADR-like membrane protein
chr11_+_123986069 0.20 ENST00000456829.2
ENST00000361352.5
ENST00000449321.1
ENST00000392748.1
ENST00000360334.4
ENST00000392744.4
VWA5A
von Willebrand factor A domain containing 5A
chr15_+_77713299 0.20 ENST00000559099.1
HMG20A
high mobility group 20A
chr14_+_78227105 0.20 ENST00000439131.2
ENST00000355883.3
ENST00000557011.1
ENST00000556047.1
C14orf178
chromosome 14 open reading frame 178
chr2_+_191334212 0.20 ENST00000444317.1
ENST00000535751.1
MFSD6
major facilitator superfamily domain containing 6
chr1_-_27226928 0.20 ENST00000361720.5
GPATCH3
G patch domain containing 3
chr1_+_86046433 0.20 ENST00000451137.2
CYR61
cysteine-rich, angiogenic inducer, 61
chr5_-_146461027 0.20 ENST00000394410.2
ENST00000508267.1
ENST00000504198.1
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr4_-_71532339 0.20 ENST00000254801.4
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr5_+_137722255 0.20 ENST00000542866.1
KDM3B
lysine (K)-specific demethylase 3B
chr1_+_206623784 0.20 ENST00000426388.1
SRGAP2
SLIT-ROBO Rho GTPase activating protein 2
chr2_-_37415690 0.20 ENST00000260637.3
ENST00000535679.1
ENST00000379149.2
SULT6B1
sulfotransferase family, cytosolic, 6B, member 1
chr8_+_94712895 0.20 ENST00000523453.1
ENST00000520955.1
FAM92A1
family with sequence similarity 92, member A1
chr11_-_119187826 0.19 ENST00000264036.4
MCAM
melanoma cell adhesion molecule
chr15_+_32933866 0.19 ENST00000300175.4
ENST00000413748.2
ENST00000494364.1
ENST00000497208.1
SCG5
secretogranin V (7B2 protein)
chr11_+_9482512 0.19 ENST00000396602.2
ENST00000530463.1
ENST00000533542.1
ENST00000532577.1
ENST00000396597.3
ZNF143
zinc finger protein 143
chr10_-_101825151 0.19 ENST00000441382.1
CPN1
carboxypeptidase N, polypeptide 1
chr6_-_26235206 0.19 ENST00000244534.5
HIST1H1D
histone cluster 1, H1d
chr20_+_58179582 0.19 ENST00000371015.1
ENST00000395639.4
PHACTR3
phosphatase and actin regulator 3
chr5_+_140186647 0.19 ENST00000512229.2
ENST00000356878.4
ENST00000530339.1
PCDHA4
protocadherin alpha 4
chr14_-_88200641 0.19 ENST00000556168.1
RP11-1152H15.1
RP11-1152H15.1
chr5_-_34043310 0.19 ENST00000231338.7
C1QTNF3
C1q and tumor necrosis factor related protein 3
chr18_+_61442629 0.19 ENST00000398019.2
ENST00000540675.1
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr16_-_1993124 0.19 ENST00000473663.1
ENST00000399753.2
ENST00000564908.1
MSRB1
methionine sulfoxide reductase B1
chr20_-_36156264 0.19 ENST00000445723.1
ENST00000414080.1
BLCAP
bladder cancer associated protein
chr9_+_133589333 0.19 ENST00000372348.2
ENST00000393293.4
ABL1
c-abl oncogene 1, non-receptor tyrosine kinase
chrX_-_41782592 0.18 ENST00000378158.1
CASK
calcium/calmodulin-dependent serine protein kinase (MAGUK family)
chr8_+_92114873 0.18 ENST00000343709.3
ENST00000448384.2
LRRC69
leucine rich repeat containing 69
chr17_-_61045902 0.18 ENST00000581596.1
RP11-180P8.3
RP11-180P8.3
chr17_-_47045949 0.18 ENST00000357424.2
GIP
gastric inhibitory polypeptide
chr12_+_96588368 0.18 ENST00000547860.1
ELK3
ELK3, ETS-domain protein (SRF accessory protein 2)
chr18_+_3451584 0.18 ENST00000551541.1
TGIF1
TGFB-induced factor homeobox 1
chr12_+_26348582 0.18 ENST00000535504.1
SSPN
sarcospan
chr5_-_36301984 0.18 ENST00000502994.1
ENST00000515759.1
ENST00000296604.3
RANBP3L
RAN binding protein 3-like
chr17_-_38256973 0.18 ENST00000246672.3
NR1D1
nuclear receptor subfamily 1, group D, member 1
chr12_-_50616382 0.17 ENST00000552783.1
LIMA1
LIM domain and actin binding 1
chr13_-_81801115 0.17 ENST00000567258.1
LINC00564
long intergenic non-protein coding RNA 564
chr16_-_3306587 0.17 ENST00000541159.1
ENST00000536379.1
ENST00000219596.1
ENST00000339854.4
MEFV
Mediterranean fever
chr11_-_8892464 0.17 ENST00000527347.1
ENST00000526241.1
ENST00000526126.1
ENST00000530938.1
ENST00000526057.1
ST5
suppression of tumorigenicity 5
chr17_+_79495397 0.17 ENST00000417245.2
ENST00000334850.7
FSCN2
fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus)
chr19_+_41281060 0.17 ENST00000594436.1
ENST00000597784.1
MIA
melanoma inhibitory activity
chr9_-_13175823 0.17 ENST00000545857.1
MPDZ
multiple PDZ domain protein
chr2_-_228244013 0.17 ENST00000304568.3
TM4SF20
transmembrane 4 L six family member 20
chr5_+_127039075 0.17 ENST00000514853.2
CTC-228N24.1
CTC-228N24.1
chr12_-_50616122 0.17 ENST00000552823.1
ENST00000552909.1
LIMA1
LIM domain and actin binding 1
chr3_-_156878482 0.17 ENST00000295925.4
CCNL1
cyclin L1
chr13_-_33924755 0.17 ENST00000439831.1
ENST00000567873.1
STARD13
StAR-related lipid transfer (START) domain containing 13
chr12_-_21910775 0.17 ENST00000539782.1
LDHB
lactate dehydrogenase B
chr11_+_13299186 0.16 ENST00000527998.1
ENST00000396441.3
ENST00000533520.1
ENST00000529825.1
ENST00000389707.4
ENST00000401424.1
ENST00000529388.1
ENST00000530357.1
ENST00000403290.1
ENST00000361003.4
ENST00000389708.3
ENST00000403510.3
ENST00000482049.1
ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr7_+_22766766 0.16 ENST00000426291.1
ENST00000401651.1
ENST00000258743.5
ENST00000420258.2
ENST00000407492.1
ENST00000401630.3
ENST00000406575.1
IL6
interleukin 6 (interferon, beta 2)
chrX_+_9431324 0.16 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
TBL1X
transducin (beta)-like 1X-linked
chr1_+_67632083 0.16 ENST00000347310.5
ENST00000371002.1
IL23R
interleukin 23 receptor
chr14_+_21569245 0.16 ENST00000556585.2
TMEM253
transmembrane protein 253
chr5_-_124082279 0.16 ENST00000513986.1
ZNF608
zinc finger protein 608
chr5_+_167718604 0.16 ENST00000265293.4
WWC1
WW and C2 domain containing 1
chr2_+_136343904 0.16 ENST00000436436.1
R3HDM1
R3H domain containing 1
chr11_-_72492903 0.16 ENST00000537947.1
STARD10
StAR-related lipid transfer (START) domain containing 10
chr6_+_106534192 0.16 ENST00000369091.2
ENST00000369096.4
PRDM1
PR domain containing 1, with ZNF domain
chr8_+_128748466 0.16 ENST00000524013.1
ENST00000520751.1
MYC
v-myc avian myelocytomatosis viral oncogene homolog
chr2_-_191885686 0.16 ENST00000432058.1
STAT1
signal transducer and activator of transcription 1, 91kDa
chr18_-_25739260 0.16 ENST00000413878.1
CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr2_-_207082748 0.16 ENST00000407325.2
ENST00000411719.1
GPR1
G protein-coupled receptor 1
chr14_-_103589246 0.16 ENST00000558224.1
ENST00000560742.1
LINC00677
long intergenic non-protein coding RNA 677
chr3_-_100565249 0.15 ENST00000495591.1
ENST00000383691.4
ENST00000466947.1
ABI3BP
ABI family, member 3 (NESH) binding protein
chr1_-_68698197 0.15 ENST00000370973.2
ENST00000370971.1
WLS
wntless Wnt ligand secretion mediator
chr17_+_20059358 0.15 ENST00000536879.1
ENST00000395522.2
ENST00000395525.3
SPECC1
sperm antigen with calponin homology and coiled-coil domains 1
chr3_+_111578131 0.15 ENST00000498699.1
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr12_+_26205496 0.15 ENST00000537946.1
ENST00000541218.1
ENST00000282884.9
ENST00000545413.1
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr6_+_144606817 0.15 ENST00000433557.1
UTRN
utrophin
chr12_-_122240792 0.15 ENST00000545885.1
ENST00000542933.1
ENST00000428029.2
ENST00000541694.1
ENST00000536662.1
ENST00000535643.1
ENST00000541657.1
AC084018.1
RHOF
AC084018.1
ras homolog family member F (in filopodia)
chr17_-_26127525 0.15 ENST00000313735.6
NOS2
nitric oxide synthase 2, inducible
chr13_-_33780133 0.15 ENST00000399365.3
STARD13
StAR-related lipid transfer (START) domain containing 13
chr16_+_67280799 0.15 ENST00000566345.2
SLC9A5
solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
chr22_-_29107919 0.15 ENST00000434810.1
ENST00000456369.1
CHEK2
checkpoint kinase 2
chr9_-_16705069 0.15 ENST00000471301.2
BNC2
basonuclin 2
chr3_-_124839648 0.15 ENST00000430155.2
SLC12A8
solute carrier family 12, member 8
chr18_-_24129367 0.15 ENST00000408011.3
KCTD1
potassium channel tetramerization domain containing 1
chr3_+_140981456 0.15 ENST00000504264.1
ACPL2
acid phosphatase-like 2
chr1_-_156675535 0.15 ENST00000368221.1
CRABP2
cellular retinoic acid binding protein 2
chr17_+_18647326 0.15 ENST00000395667.1
ENST00000395665.4
ENST00000308799.4
ENST00000301938.4
FBXW10
F-box and WD repeat domain containing 10
chr17_-_36981556 0.15 ENST00000536127.1
ENST00000225428.5
CWC25
CWC25 spliceosome-associated protein homolog (S. cerevisiae)
chrX_+_18725758 0.14 ENST00000472826.1
ENST00000544635.1
ENST00000496075.2
PPEF1
protein phosphatase, EF-hand calcium binding domain 1
chr11_-_62457371 0.14 ENST00000317449.4
LRRN4CL
LRRN4 C-terminal like
chr5_+_38148582 0.14 ENST00000508853.1
CTD-2207A17.1
CTD-2207A17.1
chr5_+_59783941 0.14 ENST00000506884.1
ENST00000504876.2
PART1
prostate androgen-regulated transcript 1 (non-protein coding)
chr2_+_162272605 0.14 ENST00000389554.3
TBR1
T-box, brain, 1
chr14_-_25479811 0.14 ENST00000550887.1
STXBP6
syntaxin binding protein 6 (amisyn)
chr11_-_46142948 0.14 ENST00000257821.4
PHF21A
PHD finger protein 21A
chr11_+_57531292 0.14 ENST00000524579.1
CTNND1
catenin (cadherin-associated protein), delta 1
chr17_-_46688334 0.14 ENST00000239165.7
HOXB7
homeobox B7
chr15_-_44969086 0.14 ENST00000434130.1
ENST00000560780.1
PATL2
protein associated with topoisomerase II homolog 2 (yeast)
chr12_+_113354341 0.14 ENST00000553152.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr22_-_36236265 0.14 ENST00000414461.2
ENST00000416721.2
ENST00000449924.2
ENST00000262829.7
ENST00000397305.3
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr11_+_111807863 0.14 ENST00000440460.2
DIXDC1
DIX domain containing 1

Network of associatons between targets according to the STRING database.

First level regulatory network of NFATC2_NFATC3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.2 0.5 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 0.6 GO:2001301 lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
0.1 0.4 GO:0070433 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of CD40 signaling pathway(GO:2000349)
0.1 0.9 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.1 0.6 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.1 0.3 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.1 0.3 GO:0042704 detection of oxygen(GO:0003032) uterine wall breakdown(GO:0042704)
0.1 0.7 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.1 1.3 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.1 0.4 GO:0072343 pancreatic stellate cell proliferation(GO:0072343) regulation of pancreatic stellate cell proliferation(GO:2000229)
0.1 0.5 GO:2000321 positive regulation of T-helper 17 cell differentiation(GO:2000321)
0.1 0.3 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.1 0.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.2 GO:1901207 regulation of heart looping(GO:1901207)
0.1 0.2 GO:0030070 insulin processing(GO:0030070)
0.1 0.3 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1 0.4 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1 0.2 GO:0060086 circadian temperature homeostasis(GO:0060086)
0.1 0.2 GO:0007341 penetration of zona pellucida(GO:0007341)
0.1 0.4 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 0.4 GO:0019075 virus maturation(GO:0019075)
0.1 0.6 GO:0051552 flavone metabolic process(GO:0051552)
0.1 0.6 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.1 0.4 GO:0035881 amacrine cell differentiation(GO:0035881)
0.1 0.2 GO:0009956 radial pattern formation(GO:0009956)
0.1 0.2 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.1 0.4 GO:0006561 proline biosynthetic process(GO:0006561)
0.1 0.3 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 0.3 GO:0072101 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.1 0.3 GO:1904528 positive regulation of microtubule binding(GO:1904528)
0.1 0.2 GO:0003363 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.0 0.1 GO:1903925 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.0 0.6 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.2 GO:0007402 ganglion mother cell fate determination(GO:0007402)
0.0 0.2 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.0 0.4 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.2 GO:0070843 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.0 0.2 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.1 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.0 0.2 GO:0021622 optic cup structural organization(GO:0003409) oculomotor nerve morphogenesis(GO:0021622) oculomotor nerve formation(GO:0021623)
0.0 0.2 GO:0030222 eosinophil differentiation(GO:0030222)
0.0 0.3 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.0 0.2 GO:0002384 hepatic immune response(GO:0002384) response to prolactin(GO:1990637)
0.0 0.2 GO:0090095 regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.0 0.2 GO:0072308 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.0 0.3 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.2 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 0.3 GO:0071313 cellular response to caffeine(GO:0071313)
0.0 0.3 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.0 0.1 GO:0035508 positive regulation of myosin-light-chain-phosphatase activity(GO:0035508)
0.0 0.7 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.2 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.0 0.3 GO:0015840 urea transport(GO:0015840)
0.0 0.2 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.0 0.1 GO:0046671 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.0 0.1 GO:1990828 response to putrescine(GO:1904585) cellular response to putrescine(GO:1904586) hepatocyte dedifferentiation(GO:1990828)
0.0 0.2 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.2 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.1 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.0 0.1 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.3 GO:0006216 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0 0.1 GO:0007506 gonadal mesoderm development(GO:0007506)
0.0 0.2 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
0.0 0.3 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.1 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.0 0.1 GO:0015783 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.0 0.3 GO:0070163 adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163)
0.0 0.1 GO:0033385 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.0 0.1 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.0 0.1 GO:0060151 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.0 0.1 GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process(GO:0046901)
0.0 0.1 GO:0030185 nitric oxide transport(GO:0030185)
0.0 0.4 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.2 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.1 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 0.3 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.1 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.0 0.1 GO:0021764 amygdala development(GO:0021764)
0.0 0.2 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.2 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.1 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.0 0.1 GO:0009386 translational attenuation(GO:0009386)
0.0 0.2 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.2 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.5 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.4 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.1 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.1 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.1 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.0 0.1 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.0 0.2 GO:2000809 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445) positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 0.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0090472 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.0 0.2 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.2 GO:0061042 vascular wound healing(GO:0061042)
0.0 0.1 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.0 0.1 GO:0010269 response to selenium ion(GO:0010269)
0.0 0.3 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.1 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.0 0.1 GO:0072658 positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.2 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.1 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0 0.1 GO:2000295 regulation of hydrogen peroxide catabolic process(GO:2000295)
0.0 0.1 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 0.0 GO:0061485 memory T cell proliferation(GO:0061485)
0.0 0.1 GO:0042823 pyridoxal phosphate biosynthetic process(GO:0042823)
0.0 0.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.1 GO:0051712 positive regulation of killing of cells of other organism(GO:0051712)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.1 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.0 0.1 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.1 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.1 GO:1903689 regulation of wound healing, spreading of epidermal cells(GO:1903689)
0.0 0.3 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.3 GO:0034116 positive regulation of heterotypic cell-cell adhesion(GO:0034116)
0.0 0.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.2 GO:0072718 response to cisplatin(GO:0072718)
0.0 0.3 GO:2001204 regulation of osteoclast development(GO:2001204)
0.0 0.0 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.0 GO:0038194 thyroid-stimulating hormone signaling pathway(GO:0038194)
0.0 0.1 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.0 0.2 GO:0030091 protein repair(GO:0030091)
0.0 0.2 GO:0032782 bile acid secretion(GO:0032782)
0.0 0.0 GO:0060722 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.0 0.0 GO:0070904 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 0.2 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.1 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.1 GO:0099612 protein localization to axon(GO:0099612)
0.0 0.1 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.1 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.2 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.0 0.1 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.3 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.0 0.2 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.1 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.1 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.0 GO:0070426 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.2 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.1 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.1 GO:0003344 pericardium morphogenesis(GO:0003344)
0.0 0.1 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.1 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.0 0.1 GO:0043387 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.0 0.0 GO:0046086 AMP catabolic process(GO:0006196) adenosine biosynthetic process(GO:0046086)
0.0 0.1 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.0 0.1 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
0.0 0.1 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.0 0.1 GO:0060536 cartilage morphogenesis(GO:0060536)
0.0 0.1 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.2 GO:0032279 asymmetric synapse(GO:0032279)
0.1 0.3 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.1 0.7 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.2 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.0 0.2 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0 0.4 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.2 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.7 GO:0070938 contractile ring(GO:0070938)
0.0 0.2 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.2 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.2 GO:1902560 GMP reductase complex(GO:1902560)
0.0 0.1 GO:0034681 integrin alpha11-beta1 complex(GO:0034681)
0.0 0.1 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.0 0.4 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.5 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.1 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.1 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.6 GO:0031143 pseudopodium(GO:0031143)
0.0 0.4 GO:0045180 basal cortex(GO:0045180)
0.0 0.2 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.1 GO:0017102 methionyl glutamyl tRNA synthetase complex(GO:0017102)
0.0 0.2 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.2 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.0 0.1 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.1 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.3 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.1 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.1 GO:0045160 myosin I complex(GO:0045160)
0.0 0.0 GO:0005899 insulin receptor complex(GO:0005899)
0.0 1.1 GO:0031526 brush border membrane(GO:0031526)
0.0 0.1 GO:1905202 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.0 0.0 GO:0005595 collagen type XII trimer(GO:0005595)
0.0 0.1 GO:0005593 FACIT collagen trimer(GO:0005593)
0.0 0.1 GO:0031906 late endosome lumen(GO:0031906)
0.0 0.7 GO:0043034 costamere(GO:0043034)
0.0 0.0 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.0 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.0 0.0 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.1 GO:0098642 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0 0.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.1 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.2 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.2 GO:0005916 fascia adherens(GO:0005916)
0.0 0.2 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.1 GO:0030057 desmosome(GO:0030057)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.2 1.1 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.2 0.6 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.1 0.6 GO:0047977 linoleate 13S-lipoxygenase activity(GO:0016165) hepoxilin-epoxide hydrolase activity(GO:0047977)
0.1 0.3 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.4 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 0.3 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.2 GO:0005174 CD40 receptor binding(GO:0005174)
0.1 0.2 GO:0042020 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.1 0.5 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.3 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.3 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.4 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.6 GO:0045159 myosin II binding(GO:0045159)
0.0 0.0 GO:1904713 beta-catenin destruction complex binding(GO:1904713)
0.0 0.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.4 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.2 GO:0003947 (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity(GO:0003947)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.4 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.9 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.3 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.1 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.2 GO:0034617 nitric-oxide synthase activity(GO:0004517) tetrahydrobiopterin binding(GO:0034617)
0.0 0.1 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.2 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0 0.2 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.3 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.2 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.4 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.0 0.1 GO:0005457 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.0 0.1 GO:0008841 tetrahydrofolylpolyglutamate synthase activity(GO:0004326) dihydrofolate synthase activity(GO:0008841)
0.0 0.3 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.2 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.1 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.0 0.2 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.2 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.0 0.6 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.2 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.2 GO:0004515 nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.4 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.1 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.0 0.1 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.1 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.2 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.3 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.1 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.8 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.1 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.2 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.0 0.1 GO:0080130 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 0.1 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.8 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.1 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.0 0.1 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.1 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.1 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.0 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.2 GO:0042731 PH domain binding(GO:0042731)
0.0 0.1 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.0 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.7 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.2 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.1 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.0 0.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.0 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.1 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.4 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.4 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.2 GO:0031628 opioid receptor binding(GO:0031628) mu-type opioid receptor binding(GO:0031852)
0.0 0.1 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.2 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0008934 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.2 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.7 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.2 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.5 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.1 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.4 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.7 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.6 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.2 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.7 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.4 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.3 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.6 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.1 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.4 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.7 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.3 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.8 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.6 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.5 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.3 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.5 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.1 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.2 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.4 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.3 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis