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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for MYOD1
Z-value: 0.82
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Transcription factors associated with MYOD1
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr22_-_21905120 Show fit | 1.87 |
ENST00000331505.5
|
RIMS binding protein 3C |
|
| chr12_-_68845417 Show fit | 0.66 |
ENST00000542875.1
|
RP11-81H14.2 |
|
| chr10_-_69991865 Show fit | 0.57 |
ENST00000373673.3
|
atonal homolog 7 (Drosophila) |
|
| chrX_+_53078465 Show fit | 0.48 |
ENST00000375466.2
|
G protein-coupled receptor 173 |
|
| chr17_+_38337491 Show fit | 0.47 |
ENST00000538981.1
|
Rap guanine nucleotide exchange factor (GEF)-like 1 |
|
| chr14_+_77582905 Show fit | 0.44 |
ENST00000557408.1
|
transmembrane protein 63C |
|
| chr7_-_130597935 Show fit | 0.43 |
ENST00000447307.1
ENST00000418546.1 |
microRNA 29a |
|
| chr3_-_52869205 Show fit | 0.38 |
ENST00000446157.2
|
musculoskeletal, embryonic nuclear protein 1 |
|
| chr8_-_41522779 Show fit | 0.32 |
ENST00000522231.1
ENST00000314214.8 ENST00000348036.4 ENST00000457297.1 ENST00000522543.1 |
ankyrin 1, erythrocytic |
|
| chr16_+_83932684 Show fit | 0.32 |
ENST00000262430.4
|
malonyl-CoA decarboxylase |
Network of associatons between targets according to the STRING database.
First level regulatory network of MYOD1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.0 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) |
| 0.0 | 0.6 | GO:0021554 | optic nerve development(GO:0021554) |
| 0.1 | 0.5 | GO:0097211 | response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211) |
| 0.0 | 0.5 | GO:0035988 | chondrocyte proliferation(GO:0035988) |
| 0.0 | 0.4 | GO:0045199 | maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199) |
| 0.0 | 0.4 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
| 0.1 | 0.3 | GO:0090273 | regulation of somatostatin secretion(GO:0090273) positive regulation of somatostatin secretion(GO:0090274) |
| 0.1 | 0.3 | GO:0032972 | regulation of muscle filament sliding speed(GO:0032972) |
| 0.1 | 0.3 | GO:0036115 | fatty-acyl-CoA catabolic process(GO:0036115) |
| 0.1 | 0.3 | GO:0090285 | negative regulation of protein glycosylation in Golgi(GO:0090285) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.7 | GO:0031430 | M band(GO:0031430) |
| 0.0 | 0.4 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
| 0.1 | 0.3 | GO:1990584 | cardiac Troponin complex(GO:1990584) |
| 0.0 | 0.3 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
| 0.0 | 0.3 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.0 | 0.3 | GO:0033093 | Weibel-Palade body(GO:0033093) |
| 0.1 | 0.2 | GO:0071821 | FANCM-MHF complex(GO:0071821) |
| 0.0 | 0.2 | GO:0008282 | ATP-sensitive potassium channel complex(GO:0008282) |
| 0.0 | 0.2 | GO:1990769 | proximal neuron projection(GO:1990769) |
| 0.0 | 0.2 | GO:0001940 | male pronucleus(GO:0001940) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.0 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
| 0.0 | 0.6 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.2 | 0.5 | GO:0004968 | gonadotropin-releasing hormone receptor activity(GO:0004968) |
| 0.0 | 0.4 | GO:0097493 | structural molecule activity conferring elasticity(GO:0097493) |
| 0.1 | 0.3 | GO:0071633 | dihydroceramidase activity(GO:0071633) |
| 0.0 | 0.3 | GO:0031013 | troponin I binding(GO:0031013) |
| 0.0 | 0.3 | GO:0043183 | vascular endothelial growth factor receptor 1 binding(GO:0043183) |
| 0.0 | 0.3 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
| 0.0 | 0.3 | GO:0045499 | chemorepellent activity(GO:0045499) |
| 0.0 | 0.2 | GO:0070579 | methylcytosine dioxygenase activity(GO:0070579) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.0 | 0.3 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 | Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1) |
| 0.0 | 0.2 | REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK | Genes involved in Negative regulation of the PI3K/AKT network |
| 0.0 | 0.2 | REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS | Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins |
| 0.0 | 0.2 | REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 | Genes involved in Signaling by activated point mutants of FGFR1 |