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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for MYB
Z-value: 1.15
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Transcription factors associated with MYB
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| MYB | hg19_v2_chr6_+_135502466_135502489 | -0.15 | 7.8e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr12_+_100967533 Show fit | 0.78 |
ENST00000550295.1
|
growth arrest-specific 2 like 3 |
|
| chr11_-_130184555 Show fit | 0.70 |
ENST00000525842.1
|
zinc finger and BTB domain containing 44 |
|
| chr5_+_98264867 Show fit | 0.67 |
ENST00000513175.1
|
CTD-2007H13.3 |
|
| chr3_-_88108192 Show fit | 0.67 |
ENST00000309534.6
|
CGG triplet repeat binding protein 1 |
|
| chr10_-_98347063 Show fit | 0.62 |
ENST00000443638.1
|
transmembrane 9 superfamily member 3 |
|
| chr2_-_61244550 Show fit | 0.59 |
ENST00000421319.1
|
pseudouridylate synthase 10 |
|
| chr11_+_130184888 Show fit | 0.57 |
ENST00000602376.1
ENST00000532116.3 ENST00000602310.1 |
RP11-121M22.1 |
|
| chr9_-_4679419 Show fit | 0.53 |
ENST00000609131.1
ENST00000607997.1 |
RP11-6J24.6 |
|
| chr7_-_127032363 Show fit | 0.52 |
ENST00000393312.1
|
zinc finger protein 800 |
|
| chr4_+_44019074 Show fit | 0.49 |
ENST00000512678.1
|
RP11-328N19.1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of MYB
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.1 | GO:0035735 | intraciliary transport involved in cilium morphogenesis(GO:0035735) |
| 0.1 | 1.0 | GO:0031119 | tRNA pseudouridine synthesis(GO:0031119) |
| 0.2 | 0.8 | GO:1903613 | regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615) |
| 0.0 | 0.8 | GO:0051131 | chaperone-mediated protein complex assembly(GO:0051131) |
| 0.0 | 0.8 | GO:0035036 | sperm-egg recognition(GO:0035036) |
| 0.0 | 0.7 | GO:0046602 | regulation of mitotic centrosome separation(GO:0046602) |
| 0.0 | 0.7 | GO:0035020 | regulation of Rac protein signal transduction(GO:0035020) |
| 0.1 | 0.6 | GO:0032485 | Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485) |
| 0.0 | 0.6 | GO:0019371 | cyclooxygenase pathway(GO:0019371) |
| 0.0 | 0.6 | GO:0061003 | positive regulation of dendritic spine morphogenesis(GO:0061003) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.4 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.0 | 0.9 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
| 0.0 | 0.8 | GO:0016461 | unconventional myosin complex(GO:0016461) |
| 0.0 | 0.8 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
| 0.0 | 0.7 | GO:0097227 | sperm annulus(GO:0097227) |
| 0.0 | 0.6 | GO:0005818 | astral microtubule(GO:0000235) aster(GO:0005818) |
| 0.0 | 0.6 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
| 0.0 | 0.6 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
| 0.1 | 0.5 | GO:0098536 | deuterosome(GO:0098536) |
| 0.0 | 0.5 | GO:0032039 | integrator complex(GO:0032039) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.4 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 0.1 | 1.0 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
| 0.0 | 0.8 | GO:0051959 | dynein light intermediate chain binding(GO:0051959) |
| 0.0 | 0.8 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
| 0.1 | 0.6 | GO:0050220 | prostaglandin-E synthase activity(GO:0050220) |
| 0.1 | 0.6 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
| 0.0 | 0.5 | GO:0004652 | polynucleotide adenylyltransferase activity(GO:0004652) |
| 0.1 | 0.4 | GO:0047057 | oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057) |
| 0.0 | 0.4 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
| 0.0 | 0.4 | GO:0046975 | histone methyltransferase activity (H3-K36 specific)(GO:0046975) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.6 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.0 | 0.3 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.6 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.0 | 0.8 | REACTOME PROCESSING OF INTRONLESS PRE MRNAS | Genes involved in Processing of Intronless Pre-mRNAs |
| 0.0 | 0.4 | REACTOME PURINE CATABOLISM | Genes involved in Purine catabolism |
| 0.0 | 0.4 | REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 0.0 | 0.4 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 0.0 | 0.4 | REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A | Genes involved in APC-Cdc20 mediated degradation of Nek2A |
| 0.0 | 0.4 | REACTOME DESTABILIZATION OF MRNA BY KSRP | Genes involved in Destabilization of mRNA by KSRP |
| 0.0 | 0.3 | REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY | Genes involved in Regulation of the Fanconi anemia pathway |
| 0.0 | 0.3 | REACTOME FANCONI ANEMIA PATHWAY | Genes involved in Fanconi Anemia pathway |
| 0.0 | 0.2 | REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR | Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |