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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for MLX_USF2_USF1_PAX2

Z-value: 1.56

Motif logo

Transcription factors associated with MLX_USF2_USF1_PAX2

Gene Symbol Gene ID Gene Info
ENSG00000108788.7 MAX dimerization protein MLX
ENSG00000105698.11 upstream transcription factor 2, c-fos interacting
ENSG00000158773.10 upstream transcription factor 1
ENSG00000075891.17 paired box 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
USF1hg19_v2_chr1_-_161015663_161015694-0.911.3e-02Click!
MLXhg19_v2_chr17_+_40719073_40719092-0.711.1e-01Click!
USF2hg19_v2_chr19_+_35759968_35760042-0.602.1e-01Click!
PAX2hg19_v2_chr10_+_102505468_102505546-0.602.1e-01Click!

Activity profile of MLX_USF2_USF1_PAX2 motif

Sorted Z-values of MLX_USF2_USF1_PAX2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_87865262 2.01 ENST00000369577.3
ENST00000518845.1
ENST00000339907.4
ENST00000496806.2
zinc finger protein 292
chr12_-_49463620 1.92 ENST00000550675.1
Ras homolog enriched in brain like 1
chr6_+_151773583 1.77 ENST00000545879.1
chromosome 6 open reading frame 211
chr8_+_126103921 1.69 ENST00000523741.1
non-SMC element 2, MMS21 homolog (S. cerevisiae)
chr2_+_46926326 1.64 ENST00000394861.2
suppressor of cytokine signaling 5
chr14_-_54955721 1.63 ENST00000554908.1
glia maturation factor, beta
chr3_+_112280857 1.55 ENST00000492406.1
ENST00000468642.1
solute carrier family 35, member A5
chr4_-_47465666 1.48 ENST00000381571.4
COMM domain containing 8
chr11_-_18343725 1.48 ENST00000531848.1
Hermansky-Pudlak syndrome 5
chr1_+_150254936 1.44 ENST00000447007.1
ENST00000369095.1
ENST00000369094.1
chromosome 1 open reading frame 51
chr12_-_90103077 1.39 ENST00000551310.1
ATPase, Ca++ transporting, plasma membrane 1
chr2_+_46926048 1.35 ENST00000306503.5
suppressor of cytokine signaling 5
chr4_-_99850243 1.32 ENST00000280892.6
ENST00000511644.1
ENST00000504432.1
ENST00000505992.1
eukaryotic translation initiation factor 4E
chr1_-_113498616 1.25 ENST00000433570.4
ENST00000538576.1
ENST00000458229.1
solute carrier family 16 (monocarboxylate transporter), member 1
chr6_-_109703634 1.23 ENST00000324953.5
ENST00000310786.4
ENST00000275080.7
ENST00000413644.2
CD164 molecule, sialomucin
chr10_-_32217717 1.22 ENST00000396144.4
ENST00000375245.4
ENST00000344936.2
ENST00000375250.5
Rho GTPase activating protein 12
chr15_+_41913690 1.22 ENST00000563576.1
MGA, MAX dimerization protein
chr12_-_123849374 1.22 ENST00000602398.1
ENST00000602750.1
strawberry notch homolog 1 (Drosophila)
chr11_+_18343800 1.20 ENST00000453096.2
general transcription factor IIH, polypeptide 1, 62kDa
chr10_+_70883908 1.18 ENST00000263559.6
ENST00000395098.1
ENST00000546041.1
ENST00000541711.1
vacuolar protein sorting 26 homolog A (S. pombe)
chr11_-_85780086 1.17 ENST00000532317.1
ENST00000528256.1
ENST00000526033.1
phosphatidylinositol binding clathrin assembly protein
chr1_-_78149041 1.16 ENST00000414381.1
ENST00000370798.1
zinc finger, ZZ-type containing 3
chr1_-_222885770 1.16 ENST00000355727.2
ENST00000340020.6
axin interactor, dorsalization associated
chr1_-_154193091 1.15 ENST00000362076.4
ENST00000350592.3
ENST00000368516.1
chromosome 1 open reading frame 43
chr19_-_49137790 1.15 ENST00000599385.1
D site of albumin promoter (albumin D-box) binding protein
chr1_+_222885884 1.14 ENST00000340934.5
BRO1 domain and CAAX motif containing
chr5_+_41904431 1.12 ENST00000381647.2
chromosome 5 open reading frame 51
chr1_-_154193009 1.12 ENST00000368518.1
ENST00000368519.1
ENST00000368521.5
chromosome 1 open reading frame 43
chr1_-_68962805 1.09 ENST00000370966.5
DEP domain containing 1
chr5_+_133706865 1.08 ENST00000265339.2
ubiquitin-conjugating enzyme E2B
chrX_-_119693745 1.08 ENST00000371323.2
cullin 4B
chr1_-_68962744 1.07 ENST00000525124.1
DEP domain containing 1
chr3_+_113465866 1.06 ENST00000273398.3
ENST00000538620.1
ENST00000496747.1
ENST00000475322.1
ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
chr19_-_49137762 1.06 ENST00000593500.1
D site of albumin promoter (albumin D-box) binding protein
chr6_-_109703663 1.06 ENST00000368961.5
CD164 molecule, sialomucin
chr13_+_42846272 1.04 ENST00000025301.2
A kinase (PRKA) anchor protein 11
chr6_+_139349903 1.03 ENST00000461027.1
ABRA C-terminal like
chr11_-_85779786 1.03 ENST00000356360.5
phosphatidylinositol binding clathrin assembly protein
chr6_-_84937314 1.03 ENST00000257766.4
ENST00000403245.3
KIAA1009
chr9_+_96928516 1.02 ENST00000602703.1
RP11-2B6.3
chr11_-_85779971 1.01 ENST00000393346.3
phosphatidylinositol binding clathrin assembly protein
chr1_-_222886526 1.01 ENST00000541237.1
axin interactor, dorsalization associated
chr9_+_6758109 1.00 ENST00000536108.1
lysine (K)-specific demethylase 4C
chr8_+_109455830 1.00 ENST00000524143.1
ER membrane protein complex subunit 2
chr3_-_113464906 0.99 ENST00000477813.1
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr1_-_68962782 0.98 ENST00000456315.2
DEP domain containing 1
chr5_+_133707252 0.97 ENST00000506787.1
ENST00000507277.1
ubiquitin-conjugating enzyme E2B
chr8_+_71581565 0.97 ENST00000408926.3
ENST00000520030.1
XK, Kell blood group complex subunit-related family, member 9
chrX_-_102319092 0.96 ENST00000372728.3
brain expressed, X-linked 1
chrX_+_102469997 0.96 ENST00000372695.5
ENST00000372691.3
brain expressed, X-linked 4
chr1_-_26233423 0.95 ENST00000357865.2
stathmin 1
chr11_-_18343669 0.95 ENST00000396253.3
ENST00000349215.3
ENST00000438420.2
Hermansky-Pudlak syndrome 5
chr15_-_50978965 0.95 ENST00000560955.1
ENST00000313478.7
transient receptor potential cation channel, subfamily M, member 7
chr2_-_211036051 0.91 ENST00000418791.1
ENST00000452086.1
ENST00000281772.9
KAT8 regulatory NSL complex subunit 1-like
chr5_-_133706695 0.89 ENST00000521755.1
ENST00000523054.1
ENST00000435240.2
ENST00000609654.1
ENST00000536186.1
ENST00000609383.1
cyclin-dependent kinase-like 3
chr11_+_18344106 0.89 ENST00000534641.1
ENST00000525831.1
ENST00000265963.4
general transcription factor IIH, polypeptide 1, 62kDa
chr12_+_28343365 0.88 ENST00000545336.1
coiled-coil domain containing 91
chr21_+_38445539 0.88 ENST00000418766.1
ENST00000450533.1
ENST00000438055.1
ENST00000355666.1
ENST00000540756.1
ENST00000399010.1
tetratricopeptide repeat domain 3
chr6_+_127588020 0.87 ENST00000309649.3
ENST00000610162.1
ENST00000610153.1
ENST00000608991.1
ENST00000480444.1
ring finger protein 146
chr5_-_132299313 0.86 ENST00000265343.5
AF4/FMR2 family, member 4
chr14_+_64970427 0.85 ENST00000553583.1
zinc finger and BTB domain containing 1
chr2_-_148778323 0.85 ENST00000440042.1
ENST00000535373.1
ENST00000540442.1
ENST00000536575.1
origin recognition complex, subunit 4
chr11_+_126081662 0.85 ENST00000528985.1
ENST00000529731.1
ENST00000360194.4
ENST00000530043.1
family with sequence similarity 118, member B
chr19_-_49016847 0.85 ENST00000598924.1
CTC-273B12.10
chr1_+_154193643 0.82 ENST00000456325.1
ubiquitin associated protein 2-like
chr2_-_47572207 0.82 ENST00000441997.1
AC073283.4
chr9_-_37576333 0.81 ENST00000541607.1
F-box protein 10
chrX_-_34675391 0.80 ENST00000275954.3
transmembrane protein 47
chr12_-_90102594 0.80 ENST00000428670.3
ATPase, Ca++ transporting, plasma membrane 1
chr1_+_40627038 0.80 ENST00000372771.4
rearranged L-myc fusion
chr3_+_19988885 0.79 ENST00000422242.1
RAB5A, member RAS oncogene family
chr3_-_169899504 0.79 ENST00000474275.1
ENST00000484931.1
ENST00000494943.1
ENST00000497658.1
ENST00000465896.1
ENST00000475729.1
ENST00000495893.2
ENST00000481639.1
ENST00000467570.1
ENST00000466189.1
polyhomeotic homolog 3 (Drosophila)
chr13_+_49684445 0.78 ENST00000398316.3
fibronectin type III domain containing 3A
chr8_-_126103948 0.78 ENST00000523297.1
KIAA0196
chr3_-_170626376 0.77 ENST00000487522.1
ENST00000474417.1
eukaryotic translation initiation factor 5A2
chr1_+_11866270 0.77 ENST00000376497.3
ENST00000376487.3
ENST00000376496.3
chloride channel, voltage-sensitive 6
chr8_-_54755459 0.76 ENST00000524234.1
ENST00000521275.1
ENST00000396774.2
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr14_-_92572894 0.76 ENST00000532032.1
ENST00000506466.1
ENST00000555381.1
ENST00000557311.1
ENST00000554592.1
ENST00000554672.1
ENST00000553491.1
ENST00000556220.1
ENST00000502250.1
ENST00000503767.1
ENST00000393287.5
ENST00000340660.6
ENST00000545170.1
ENST00000429774.2
ataxin 3
chr8_+_109455845 0.75 ENST00000220853.3
ER membrane protein complex subunit 2
chr5_+_122110691 0.75 ENST00000379516.2
ENST00000505934.1
ENST00000514949.1
sorting nexin 2
chr1_-_78148324 0.75 ENST00000370801.3
ENST00000433749.1
zinc finger, ZZ-type containing 3
chr3_-_112280709 0.74 ENST00000402314.2
ENST00000283290.5
ENST00000492886.1
autophagy related 3
chr15_-_59041768 0.74 ENST00000402627.1
ENST00000396140.2
ENST00000559053.1
ENST00000561288.1
ADAM metallopeptidase domain 10
chr14_+_64970662 0.74 ENST00000556965.1
ENST00000554015.1
zinc finger and BTB domain containing 1
chr11_+_85339623 0.74 ENST00000358867.6
ENST00000534341.1
ENST00000393375.1
ENST00000531274.1
transmembrane protein 126B
chrX_+_100663243 0.73 ENST00000316594.5
heterogeneous nuclear ribonucleoprotein H2 (H')
chr21_-_38445470 0.73 ENST00000399098.1
phosphatidylinositol glycan anchor biosynthesis, class P
chr7_+_36429424 0.73 ENST00000396068.2
anillin, actin binding protein
chr9_-_103115135 0.72 ENST00000537512.1
testis expressed 10
chr1_-_113498943 0.72 ENST00000369626.3
solute carrier family 16 (monocarboxylate transporter), member 1
chr6_+_127587755 0.72 ENST00000368314.1
ENST00000476956.1
ENST00000609447.1
ENST00000356799.2
ENST00000477776.1
ENST00000609944.1
ring finger protein 146
chr9_-_100684769 0.71 ENST00000455506.1
ENST00000375117.4
chromosome 9 open reading frame 156
chr6_+_64345698 0.70 ENST00000506783.1
ENST00000481385.2
ENST00000515594.1
ENST00000494284.2
ENST00000262043.3
PHD finger protein 3
chr15_+_82555125 0.69 ENST00000566205.1
ENST00000339465.5
ENST00000569120.1
ENST00000566861.1
family with sequence similarity 154, member B
chr3_-_134204815 0.69 ENST00000514612.1
ENST00000510994.1
ENST00000354910.5
anaphase promoting complex subunit 13
chr12_+_104359576 0.69 ENST00000392872.3
ENST00000436021.2
thymine-DNA glycosylase
chr1_+_154193325 0.68 ENST00000428931.1
ENST00000441890.1
ENST00000271877.7
ENST00000412596.1
ENST00000368504.1
ENST00000437652.1
ubiquitin associated protein 2-like
chr10_-_120514720 0.67 ENST00000369151.3
ENST00000340214.4
CDK2-associated, cullin domain 1
chr12_+_104359614 0.67 ENST00000266775.9
ENST00000544861.1
thymine-DNA glycosylase
chr12_+_105501487 0.67 ENST00000332180.5
KIAA1033
chr1_-_42921915 0.67 ENST00000372565.3
ENST00000433602.2
zinc finger, MYND-type containing 12
chrX_+_55744228 0.67 ENST00000262850.7
Ras-related GTP binding B
chr6_-_109703600 0.67 ENST00000512821.1
CD164 molecule, sialomucin
chr11_+_107879459 0.67 ENST00000393094.2
cullin 5
chrX_+_149737046 0.67 ENST00000370396.2
ENST00000542741.1
ENST00000543350.1
ENST00000424519.1
ENST00000413012.2
myotubularin 1
chr5_+_172483347 0.67 ENST00000522692.1
ENST00000296953.2
ENST00000540014.1
ENST00000520420.1
CREB3 regulatory factor
chr10_+_22605374 0.66 ENST00000448361.1
COMM domain containing 3
chr2_-_98612379 0.66 ENST00000425805.2
transmembrane protein 131
chr1_+_33116743 0.65 ENST00000414241.3
ENST00000373493.5
retinoblastoma binding protein 4
chr8_+_126104076 0.65 ENST00000517532.1
ENST00000287437.3
ENST00000518013.1
ENST00000522563.1
non-SMC element 2, MMS21 homolog (S. cerevisiae)
chr12_+_64845864 0.65 ENST00000538890.1
TANK-binding kinase 1
chr17_+_62503073 0.65 ENST00000580188.1
ENST00000581056.1
centrosomal protein 95kDa
chr3_+_140660634 0.64 ENST00000446041.2
ENST00000507429.1
ENST00000324194.6
solute carrier family 25 (pyrimidine nucleotide carrier ), member 36
chrX_+_55744166 0.64 ENST00000374941.4
ENST00000414239.1
Ras-related GTP binding B
chr9_+_74526384 0.64 ENST00000334731.2
ENST00000377031.3
chromosome 9 open reading frame 85
chr2_-_176866978 0.64 ENST00000392540.2
ENST00000409660.1
ENST00000544803.1
ENST00000272748.4
KIAA1715
chr17_+_74723031 0.64 ENST00000586200.1
methyltransferase like 23
chr12_+_104359641 0.63 ENST00000537100.1
thymine-DNA glycosylase
chrX_+_77166172 0.63 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATPase, Cu++ transporting, alpha polypeptide
chr18_+_9136758 0.63 ENST00000383440.2
ENST00000262126.4
ENST00000577992.1
ankyrin repeat domain 12
chr3_+_158519654 0.62 ENST00000415822.2
ENST00000392813.4
ENST00000264266.8
major facilitator superfamily domain containing 1
chr1_-_26232522 0.61 ENST00000399728.1
stathmin 1
chr14_-_35591433 0.61 ENST00000261475.5
ENST00000555644.1
protein phosphatase 2, regulatory subunit B'', gamma
chr2_-_148778258 0.61 ENST00000392857.5
ENST00000457954.1
ENST00000392858.1
ENST00000542387.1
origin recognition complex, subunit 4
chr10_+_112327425 0.61 ENST00000361804.4
structural maintenance of chromosomes 3
chr1_+_42921761 0.60 ENST00000372562.1
phosphopantothenoylcysteine synthetase
chr1_-_115259337 0.59 ENST00000369535.4
neuroblastoma RAS viral (v-ras) oncogene homolog
chr3_+_133292759 0.59 ENST00000431519.2
CDV3 homolog (mouse)
chr1_+_52521797 0.59 ENST00000313334.8
basic transcription factor 3-like 4
chr5_+_110074685 0.58 ENST00000355943.3
ENST00000447245.2
solute carrier family 25, member 46
chr1_-_186649543 0.58 ENST00000367468.5
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr7_+_36429409 0.58 ENST00000265748.2
anillin, actin binding protein
chr1_-_26232951 0.58 ENST00000426559.2
ENST00000455785.2
stathmin 1
chr8_-_126103969 0.57 ENST00000517845.1
KIAA0196
chr14_-_54955376 0.57 ENST00000553333.1
glia maturation factor, beta
chr8_+_98656693 0.57 ENST00000519934.1
metadherin
chr21_-_40720974 0.56 ENST00000380748.1
high mobility group nucleosome binding domain 1
chr14_-_54908043 0.56 ENST00000556113.1
ENST00000553660.1
ENST00000395573.4
ENST00000557690.1
ENST00000216416.4
cornichon family AMPA receptor auxiliary protein 1
chr1_+_186649754 0.56 ENST00000608917.1
RP5-973M2.2
chrX_+_30671476 0.56 ENST00000378946.3
ENST00000378943.3
ENST00000378945.3
ENST00000427190.1
ENST00000378941.3
glycerol kinase
chr12_+_64846129 0.56 ENST00000540417.1
ENST00000539810.1
TANK-binding kinase 1
chr1_-_202896310 0.56 ENST00000367261.3
kelch-like family member 12
chrX_-_102510120 0.56 ENST00000451678.1
transcription elongation factor A (SII)-like 8
chrX_-_100662881 0.55 ENST00000218516.3
galactosidase, alpha
chrX_+_131157322 0.55 ENST00000481105.1
ENST00000354719.6
ENST00000394335.2
Serine/threonine-protein kinase MST4
chr1_+_52521957 0.55 ENST00000472944.2
ENST00000484036.1
basic transcription factor 3-like 4
chr8_-_126104055 0.55 ENST00000318410.7
KIAA0196
chr6_-_106773291 0.54 ENST00000343245.3
autophagy related 5
chr2_-_198364581 0.54 ENST00000428204.1
heat shock 60kDa protein 1 (chaperonin)
chr12_+_51632508 0.54 ENST00000449723.3
DAZ associated protein 2
chr14_+_35591020 0.54 ENST00000603611.1
KIAA0391
chr9_-_125667618 0.54 ENST00000423239.2
ring finger and CCCH-type domains 2
chr4_-_83934078 0.54 ENST00000505397.1
lin-54 homolog (C. elegans)
chr3_-_53080644 0.53 ENST00000497586.1
Scm-like with four mbt domains 1
chr3_+_140660743 0.53 ENST00000453248.2
solute carrier family 25 (pyrimidine nucleotide carrier ), member 36
chrX_+_102883887 0.53 ENST00000372625.3
ENST00000372624.3
transcription elongation factor A (SII)-like 1
chrX_+_131157290 0.53 ENST00000394334.2
Serine/threonine-protein kinase MST4
chr5_-_131132614 0.53 ENST00000307968.7
ENST00000307954.8
folliculin interacting protein 1
chr18_+_9708162 0.52 ENST00000578921.1
RAB31, member RAS oncogene family
chr2_-_44223138 0.52 ENST00000260665.7
leucine-rich pentatricopeptide repeat containing
chr17_-_49337392 0.51 ENST00000376381.2
ENST00000586178.1
mbt domain containing 1
chr5_-_168006591 0.51 ENST00000239231.6
pantothenate kinase 3
chr1_-_31845914 0.51 ENST00000373713.2
fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
chr9_+_74526532 0.51 ENST00000486911.2
chromosome 9 open reading frame 85
chrX_+_146993534 0.51 ENST00000334557.6
ENST00000439526.2
ENST00000370475.4
fragile X mental retardation 1
chr4_-_15656923 0.51 ENST00000382358.4
ENST00000412094.2
ENST00000341285.3
F-box and leucine-rich repeat protein 5
chr8_+_74903580 0.51 ENST00000284818.2
ENST00000518893.1
lymphocyte antigen 96
chr2_+_27805880 0.50 ENST00000379717.1
ENST00000355467.4
ENST00000556601.1
ENST00000416005.2
zinc finger protein 512
chr6_-_7313381 0.50 ENST00000489567.1
ENST00000479365.1
ENST00000462112.1
ENST00000397511.2
ENST00000534851.1
ENST00000474597.1
ENST00000244763.4
signal sequence receptor, alpha
chr16_-_57219721 0.50 ENST00000562406.1
ENST00000568671.1
ENST00000567044.1
family with sequence similarity 192, member A
chr3_+_19988566 0.50 ENST00000273047.4
RAB5A, member RAS oncogene family
chrY_-_15591485 0.49 ENST00000382896.4
ENST00000537580.1
ENST00000540140.1
ENST00000545955.1
ENST00000538878.1
ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
chr12_+_64845660 0.49 ENST00000331710.5
TANK-binding kinase 1
chrX_-_102510126 0.49 ENST00000372685.3
transcription elongation factor A (SII)-like 8
chr5_-_94890648 0.49 ENST00000513823.1
ENST00000514952.1
ENST00000358746.2
tetratricopeptide repeat domain 37
chr9_+_6758024 0.49 ENST00000442236.2
lysine (K)-specific demethylase 4C
chr1_-_207226313 0.48 ENST00000367084.1
YOD1 deubiquitinase
chr7_+_92861653 0.48 ENST00000251739.5
ENST00000305866.5
ENST00000544910.1
ENST00000541136.1
ENST00000458530.1
ENST00000535481.1
ENST00000317751.6
coiled-coil domain containing 132
chr16_-_15736953 0.48 ENST00000548025.1
ENST00000551742.1
ENST00000602337.1
ENST00000344181.3
ENST00000396368.3
KIAA0430
chr8_-_54755789 0.48 ENST00000359530.2
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr12_+_101673872 0.48 ENST00000261637.4
UTP20, small subunit (SSU) processome component, homolog (yeast)
chr14_-_81687197 0.48 ENST00000553612.1
general transcription factor IIA, 1, 19/37kDa
chrX_-_102510045 0.48 ENST00000360000.4
transcription elongation factor A (SII)-like 8
chr2_+_216176761 0.48 ENST00000540518.1
ENST00000435675.1
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr6_-_33385823 0.48 ENST00000494751.1
ENST00000374496.3
cutA divalent cation tolerance homolog (E. coli)
chr19_+_32836499 0.47 ENST00000311921.4
ENST00000544431.1
ENST00000355898.5
zinc finger protein 507
chr17_+_17876127 0.47 ENST00000582416.1
ENST00000313838.8
ENST00000411504.2
ENST00000581264.1
ENST00000399187.1
ENST00000479684.2
ENST00000584166.1
ENST00000585108.1
ENST00000399182.1
ENST00000579977.1
leucine rich repeat containing 48
chr8_+_94929273 0.47 ENST00000518573.1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chrX_+_131157609 0.46 ENST00000496850.1
Serine/threonine-protein kinase MST4
chr5_-_132299290 0.46 ENST00000378595.3
AF4/FMR2 family, member 4
chr4_+_38665810 0.46 ENST00000261438.5
ENST00000514033.1
Kruppel-like factor 3 (basic)
chr2_-_197036289 0.46 ENST00000263955.4
serine/threonine kinase 17b
chr9_-_123476612 0.46 ENST00000426959.1
multiple EGF-like-domains 9
chr21_-_38445011 0.46 ENST00000464265.1
ENST00000399102.1
phosphatidylinositol glycan anchor biosynthesis, class P
chr18_-_29522989 0.46 ENST00000582539.1
ENST00000283351.4
ENST00000582513.1
trafficking protein particle complex 8
chr3_+_148847371 0.45 ENST00000296051.2
ENST00000460120.1
Hermansky-Pudlak syndrome 3
chr1_+_52521928 0.45 ENST00000489308.2
basic transcription factor 3-like 4
chr7_-_27135591 0.45 ENST00000343060.4
ENST00000355633.5
homeobox A1
chr11_-_126081532 0.45 ENST00000533628.1
ENST00000298317.4
ENST00000532674.1
RNA pseudouridylate synthase domain containing 4
chr18_+_77867177 0.45 ENST00000560752.1
ADNP homeobox 2

Network of associatons between targets according to the STRING database.

First level regulatory network of MLX_USF2_USF1_PAX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.7 2.0 GO:0051780 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
0.5 3.5 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.5 2.0 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.5 2.3 GO:0034184 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.4 1.3 GO:0000921 septin ring assembly(GO:0000921) septin ring organization(GO:0031106)
0.4 1.2 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.4 1.6 GO:2000176 regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.3 2.2 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.3 0.9 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.3 0.9 GO:0000961 negative regulation of mitochondrial RNA catabolic process(GO:0000961)
0.3 2.7 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.3 0.9 GO:1900075 regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
0.3 0.6 GO:0031394 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.3 2.2 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.3 1.9 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.2 1.7 GO:2000619 negative regulation of histone H4-K16 acetylation(GO:2000619)
0.2 0.7 GO:0044830 modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254)
0.2 2.2 GO:1990034 cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034)
0.2 0.9 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.2 0.7 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.2 1.7 GO:0044565 dendritic cell proliferation(GO:0044565)
0.2 1.5 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.2 0.8 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.2 1.0 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.2 0.5 GO:0002368 B cell cytokine production(GO:0002368) protein import into mitochondrial intermembrane space(GO:0045041)
0.2 1.7 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.2 0.7 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.2 1.1 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.2 0.5 GO:0000967 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.2 0.6 GO:0034756 regulation of iron ion transport(GO:0034756) regulation of iron ion transmembrane transport(GO:0034759) cellular response to lead ion(GO:0071284)
0.1 0.6 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.1 0.6 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.1 1.3 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.1 0.7 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 0.4 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.1 2.2 GO:0048262 determination of dorsal/ventral asymmetry(GO:0048262)
0.1 0.7 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 1.2 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
0.1 0.5 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
0.1 1.6 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.1 1.2 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.1 0.3 GO:1904761 negative regulation of myofibroblast differentiation(GO:1904761)
0.1 0.3 GO:1903676 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.1 0.3 GO:0051086 chaperone mediated protein folding independent of cofactor(GO:0051086)
0.1 0.8 GO:0044789 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.1 0.5 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.1 0.5 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.1 0.8 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.1 0.7 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 0.2 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.1 0.4 GO:0071230 cellular response to amino acid stimulus(GO:0071230)
0.1 0.1 GO:1902954 regulation of early endosome to recycling endosome transport(GO:1902954)
0.1 0.6 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 0.2 GO:0000960 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960) mitochondrial RNA 3'-end processing(GO:0000965)
0.1 2.2 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1 0.6 GO:2000973 regulation of pro-B cell differentiation(GO:2000973)
0.1 1.0 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.1 0.3 GO:0045872 regulation of rhodopsin gene expression(GO:0007468) positive regulation of rhodopsin gene expression(GO:0045872)
0.1 1.5 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1 0.2 GO:1903567 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.1 0.3 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.1 0.6 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 0.3 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1 2.2 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.1 0.3 GO:0006294 nucleotide-excision repair, preincision complex assembly(GO:0006294)
0.1 0.2 GO:0015917 aminophospholipid transport(GO:0015917)
0.1 1.7 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 0.8 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.1 0.8 GO:1904379 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.1 0.4 GO:0071344 diphosphate metabolic process(GO:0071344)
0.1 0.5 GO:0061055 myotome development(GO:0061055)
0.1 0.7 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.1 0.4 GO:0015670 carbon dioxide transport(GO:0015670)
0.1 0.8 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.1 0.8 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.1 0.2 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878) positive regulation of mitochondrial DNA metabolic process(GO:1901860) response to methionine(GO:1904640)
0.1 0.3 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.1 0.3 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.1 0.6 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 0.8 GO:0015074 DNA integration(GO:0015074)
0.1 0.2 GO:0002232 leukocyte chemotaxis involved in inflammatory response(GO:0002232)
0.1 0.2 GO:0007343 egg activation(GO:0007343)
0.1 0.3 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 0.6 GO:1901314 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.1 0.4 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 1.5 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 0.3 GO:1904933 regulation of cell proliferation in midbrain(GO:1904933)
0.1 0.3 GO:1904884 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.1 0.4 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.1 0.2 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.1 0.3 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.1 0.3 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 0.5 GO:0030242 pexophagy(GO:0030242)
0.1 0.3 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.1 0.2 GO:0071922 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922) negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.0 0.4 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0 0.4 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.2 GO:0009386 translational attenuation(GO:0009386)
0.0 0.1 GO:0044209 AMP salvage(GO:0044209)
0.0 0.7 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 1.0 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.7 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.2 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.0 0.2 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.0 0.2 GO:0043103 hypoxanthine salvage(GO:0043103)
0.0 0.4 GO:0021603 cranial nerve formation(GO:0021603)
0.0 0.4 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.8 GO:0030575 nuclear body organization(GO:0030575)
0.0 0.1 GO:0070101 positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.0 0.7 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.6 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.2 GO:0003165 Purkinje myocyte development(GO:0003165)
0.0 0.1 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.2 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.2 GO:0035350 FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350)
0.0 0.4 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.2 GO:1904764 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.0 0.2 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 1.2 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.1 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.2 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.0 0.2 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.0 0.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 2.8 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.2 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.0 0.1 GO:0051462 cortisol secretion(GO:0043400) regulation of cortisol secretion(GO:0051462)
0.0 0.3 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.0 0.9 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.7 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.0 0.3 GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway(GO:0007178)
0.0 0.3 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.3 GO:0097106 postsynaptic density organization(GO:0097106)
0.0 0.2 GO:0042695 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0 0.4 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0 0.5 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.1 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.0 0.1 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.0 0.4 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.8 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.0 0.2 GO:0048254 snoRNA localization(GO:0048254)
0.0 0.2 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.1 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.0 0.2 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.4 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.1 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.4 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.5 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.2 GO:0015798 myo-inositol transport(GO:0015798)
0.0 0.3 GO:0036337 Fas signaling pathway(GO:0036337) regulation of Fas signaling pathway(GO:1902044)
0.0 0.1 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.1 GO:0061290 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.0 0.2 GO:0002005 angiotensin catabolic process in blood(GO:0002005)
0.0 0.5 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.2 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.0 0.2 GO:0007135 meiosis II(GO:0007135)
0.0 0.2 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.1 GO:2000657 regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657)
0.0 0.3 GO:0021769 orbitofrontal cortex development(GO:0021769)
0.0 0.2 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 0.3 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 1.0 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0 0.1 GO:0061743 motor learning(GO:0061743)
0.0 0.3 GO:1902570 protein localization to nucleolus(GO:1902570)
0.0 0.2 GO:1903751 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.0 0.3 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.1 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.0 0.1 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.0 0.1 GO:0070980 biphenyl catabolic process(GO:0070980)
0.0 0.1 GO:1902908 regulation of melanosome transport(GO:1902908)
0.0 0.2 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.6 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.4 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.1 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.0 0.2 GO:1902741 interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.0 0.1 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.2 GO:2001235 positive regulation of apoptotic signaling pathway(GO:2001235)
0.0 0.1 GO:1990637 response to prolactin(GO:1990637)
0.0 0.1 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.0 0.1 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.5 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0042701 progesterone secretion(GO:0042701)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.3 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.0 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.0 1.3 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
0.0 0.7 GO:0016180 snRNA processing(GO:0016180)
0.0 0.3 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.6 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.1 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.0 0.4 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.1 GO:0002003 angiotensin maturation(GO:0002003)
0.0 0.1 GO:0002636 positive regulation of germinal center formation(GO:0002636)
0.0 0.1 GO:0036451 cap mRNA methylation(GO:0036451)
0.0 0.4 GO:1904816 positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
0.0 0.2 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.4 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 1.5 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.2 GO:2000643 positive regulation of early endosome to late endosome transport(GO:2000643)
0.0 0.3 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.5 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.3 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.1 GO:0042360 vitamin E metabolic process(GO:0042360)
0.0 0.7 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.2 GO:0097338 response to clozapine(GO:0097338)
0.0 0.4 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.8 GO:0070987 error-free translesion synthesis(GO:0070987)
0.0 0.1 GO:0051029 rRNA transport(GO:0051029)
0.0 0.3 GO:0014029 neural crest formation(GO:0014029)
0.0 0.1 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 0.0 GO:0043317 cytotoxic T cell degranulation(GO:0043316) regulation of cytotoxic T cell degranulation(GO:0043317) negative regulation of cytotoxic T cell degranulation(GO:0043318)
0.0 0.3 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.0 0.1 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 0.1 GO:0043201 response to leucine(GO:0043201)
0.0 0.1 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.3 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 0.6 GO:0072600 establishment of protein localization to Golgi(GO:0072600)
0.0 0.7 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.1 GO:0060382 regulation of DNA strand elongation(GO:0060382)
0.0 0.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.1 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.0 0.1 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.4 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.1 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.2 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:0007538 primary sex determination(GO:0007538)
0.0 0.6 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.5 GO:0070911 global genome nucleotide-excision repair(GO:0070911)
0.0 0.1 GO:0048478 replication fork protection(GO:0048478)
0.0 0.3 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0 0.2 GO:0000075 cell cycle checkpoint(GO:0000075)
0.0 1.1 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.0 0.1 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.2 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.0 0.2 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.1 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
0.0 1.7 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.1 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.0 1.9 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0 0.3 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.2 GO:0015820 leucine transport(GO:0015820)
0.0 0.1 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.0 0.1 GO:0006050 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.0 0.0 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.1 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 0.1 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0 0.2 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.3 GO:0016081 synaptic vesicle docking(GO:0016081)
0.0 0.1 GO:1990834 response to odorant(GO:1990834)
0.0 0.1 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 0.1 GO:0051013 microtubule severing(GO:0051013)
0.0 0.1 GO:0046668 regulation of retinal cell programmed cell death(GO:0046668)
0.0 0.1 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.2 GO:0072189 ureter development(GO:0072189)
0.0 0.1 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.0 0.0 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
0.0 0.3 GO:0060441 epithelial tube branching involved in lung morphogenesis(GO:0060441)
0.0 0.2 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.1 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.1 GO:0010767 regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010767)
0.0 0.2 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.1 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097)
0.0 0.0 GO:0002384 hepatic immune response(GO:0002384)
0.0 1.2 GO:0043297 apical junction assembly(GO:0043297)
0.0 0.1 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.0 0.1 GO:0006907 pinocytosis(GO:0006907)
0.0 0.1 GO:0030323 respiratory tube development(GO:0030323)
0.0 0.1 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.0 0.2 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.8 GO:0030317 sperm motility(GO:0030317)
0.0 0.1 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.0 0.1 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.0 0.0 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.1 GO:0036289 peptidyl-serine autophosphorylation(GO:0036289)
0.0 0.0 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 0.0 GO:0021571 rhombomere 5 development(GO:0021571)
0.0 0.0 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.0 0.1 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.3 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.1 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.1 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 1.0 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.1 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.0 0.1 GO:0019557 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.0 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 0.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.1 GO:0046823 negative regulation of protein import into nucleus(GO:0042308) negative regulation of nucleocytoplasmic transport(GO:0046823) negative regulation of protein import(GO:1904590)
0.0 0.1 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.3 GO:0001504 neurotransmitter uptake(GO:0001504)
0.0 0.1 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.2 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.0 0.0 GO:0010623 programmed cell death involved in cell development(GO:0010623)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.9 GO:0031084 BLOC-2 complex(GO:0031084)
0.6 3.6 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.3 1.9 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.3 1.7 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.3 2.3 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.2 0.7 GO:1902737 dendritic filopodium(GO:1902737)
0.2 1.2 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.2 1.3 GO:0005826 actomyosin contractile ring(GO:0005826)
0.2 2.1 GO:0033503 HULC complex(GO:0033503)
0.2 1.6 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.2 2.1 GO:0000439 core TFIIH complex(GO:0000439)
0.2 1.4 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.2 1.3 GO:0031415 NatA complex(GO:0031415)
0.1 3.4 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 2.1 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 1.5 GO:0016589 NURF complex(GO:0016589)
0.1 0.5 GO:0055087 Ski complex(GO:0055087)
0.1 0.1 GO:0032156 septin cytoskeleton(GO:0032156)
0.1 1.0 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.8 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 1.7 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 1.1 GO:0033263 CORVET complex(GO:0033263)
0.1 0.6 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.1 2.2 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 1.0 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 0.9 GO:0030905 retromer, tubulation complex(GO:0030905)
0.1 0.3 GO:0005960 glycine cleavage complex(GO:0005960)
0.1 0.9 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 0.9 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.1 0.3 GO:0032279 asymmetric synapse(GO:0032279) symmetric synapse(GO:0032280)
0.1 0.3 GO:0070985 TFIIK complex(GO:0070985)
0.1 1.0 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 1.3 GO:0033391 chromatoid body(GO:0033391)
0.1 0.4 GO:0000801 central element(GO:0000801)
0.1 0.9 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.1 0.3 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.1 0.8 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.6 GO:0005787 signal peptidase complex(GO:0005787)
0.1 0.4 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 0.5 GO:0070876 SOSS complex(GO:0070876)
0.1 1.1 GO:0016461 unconventional myosin complex(GO:0016461)
0.1 0.8 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 0.8 GO:0032039 integrator complex(GO:0032039)
0.1 1.9 GO:0005721 pericentric heterochromatin(GO:0005721)
0.1 1.0 GO:0097227 sperm annulus(GO:0097227)
0.1 0.2 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.9 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.5 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.5 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 1.8 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 1.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.3 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.1 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.0 0.1 GO:0033597 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
0.0 0.3 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.2 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.8 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.1 GO:0032797 SMN complex(GO:0032797)
0.0 0.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.7 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 1.2 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.1 GO:0034657 GID complex(GO:0034657)
0.0 0.3 GO:0036128 CatSper complex(GO:0036128)
0.0 0.4 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.3 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.1 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.4 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.1 GO:0043614 multi-eIF complex(GO:0043614)
0.0 0.2 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.1 GO:0005595 collagen type XII trimer(GO:0005595)
0.0 0.6 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.8 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.4 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.4 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.4 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 1.2 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.1 GO:0097232 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.0 1.1 GO:0090544 BAF-type complex(GO:0090544)
0.0 0.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.4 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0 0.1 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.0 1.3 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.1 GO:0034676 integrin alpha6-beta4 complex(GO:0034676)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940) mitotic spindle midzone(GO:1990023)
0.0 0.1 GO:0070701 mucus layer(GO:0070701)
0.0 0.6 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.5 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.6 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.2 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.1 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.4 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.1 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.0 0.7 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.4 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 0.1 GO:0000124 SAGA complex(GO:0000124)
0.0 0.2 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.0 GO:0001534 radial spoke(GO:0001534)
0.0 0.4 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.1 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.1 GO:0043196 varicosity(GO:0043196)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 0.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.2 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.1 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.3 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.0 1.8 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.3 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.1 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 0.1 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 0.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 1.1 GO:0005902 microvillus(GO:0005902)
0.0 0.4 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.2 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.0 0.1 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.7 2.0 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
0.4 1.2 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.4 2.1 GO:0019776 Atg8 ligase activity(GO:0019776)
0.3 3.6 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.2 1.6 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.2 0.7 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.2 2.6 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.2 2.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.2 0.5 GO:0070538 oleic acid binding(GO:0070538)
0.2 0.6 GO:0032767 copper-dependent protein binding(GO:0032767)
0.2 0.6 GO:0036033 mediator complex binding(GO:0036033)
0.1 0.4 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.1 0.7 GO:1990460 leptin receptor binding(GO:1990460)
0.1 0.4 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.1 1.4 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 0.4 GO:0033149 FFAT motif binding(GO:0033149)
0.1 0.5 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.1 0.9 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.8 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.4 GO:0032129 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.1 0.6 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473)
0.1 0.7 GO:0034046 poly(G) binding(GO:0034046)
0.1 1.8 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 2.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 0.5 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.1 0.9 GO:0019238 cyclohydrolase activity(GO:0019238)
0.1 2.8 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 0.3 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.1 0.2 GO:0098770 FBXO family protein binding(GO:0098770)
0.1 0.3 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 1.4 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 0.2 GO:0005365 myo-inositol transmembrane transporter activity(GO:0005365)
0.1 2.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.3 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.1 0.5 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.3 GO:0001601 peptide YY receptor activity(GO:0001601)
0.1 0.3 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 0.3 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1 0.8 GO:0097016 L27 domain binding(GO:0097016)
0.1 0.4 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.1 0.3 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.6 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 0.5 GO:0033592 RNA strand annealing activity(GO:0033592)
0.1 0.3 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.1 0.3 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.1 1.4 GO:0005351 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.1 3.2 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 0.9 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.3 GO:0016936 galactoside binding(GO:0016936)
0.0 0.4 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.3 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.1 GO:0004772 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.0 0.5 GO:0031386 protein tag(GO:0031386)
0.0 2.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.2 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.0 0.2 GO:0000248 C-5 sterol desaturase activity(GO:0000248) sterol desaturase activity(GO:0070704)
0.0 0.1 GO:0030984 kininogen binding(GO:0030984)
0.0 0.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.6 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.6 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.3 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.2 GO:0015230 FAD transmembrane transporter activity(GO:0015230)
0.0 0.6 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.2 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.2 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.4 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.1 GO:0001147 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.0 0.4 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 1.2 GO:0036442 hydrogen-exporting ATPase activity(GO:0036442)
0.0 2.0 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0 0.1 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.2 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.7 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.3 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.2 GO:0044594 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.0 0.1 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.0 0.2 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.2 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.2 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.4 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 1.9 GO:0050699 WW domain binding(GO:0050699)
0.0 0.3 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.3 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 1.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.9 GO:0043495 protein anchor(GO:0043495)
0.0 0.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.1 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.1 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.0 0.1 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
0.0 0.1 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.0 0.3 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.5 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.0 2.6 GO:0019003 GDP binding(GO:0019003)
0.0 0.3 GO:0015250 water channel activity(GO:0015250)
0.0 0.5 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.2 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.1 GO:0097677 STAT family protein binding(GO:0097677)
0.0 0.1 GO:0001129 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
0.0 1.0 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.3 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.0 0.3 GO:0015288 porin activity(GO:0015288)
0.0 0.1 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.0 0.1 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.1 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.0 0.2 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.1 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.4 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.0 0.7 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.5 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.1 GO:0004104 acetylcholinesterase activity(GO:0003990) cholinesterase activity(GO:0004104)
0.0 0.2 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.2 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.6 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.2 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.4 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.6 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.0 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.0 0.2 GO:0034452 dynactin binding(GO:0034452)
0.0 0.0 GO:0072545 tyrosine binding(GO:0072545)
0.0 0.0 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.0 0.3 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.6 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.0 0.0 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.0 0.8 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.4 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.1 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.0 0.0 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.0 0.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.8 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.1 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.0 0.1 GO:0050436 microfibril binding(GO:0050436)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.4 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.1 GO:0099600 transmembrane receptor activity(GO:0099600)
0.0 0.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.8 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 0.2 GO:0043047 single-stranded telomeric DNA binding(GO:0043047)
0.0 0.1 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.0 GO:0015229 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.1 GO:0050692 DBD domain binding(GO:0050692)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 1.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.8 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.1 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 3.1 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.4 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 1.2 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.1 PID IL5 PATHWAY IL5-mediated signaling events
0.0 1.7 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 2.9 PID CMYB PATHWAY C-MYB transcription factor network
0.0 2.4 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.0 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.5 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.2 PID MYC PATHWAY C-MYC pathway
0.0 1.8 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.9 PID E2F PATHWAY E2F transcription factor network
0.0 0.7 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.0 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.7 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.7 PID AURORA A PATHWAY Aurora A signaling
0.0 1.0 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.1 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 1.1 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.8 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.6 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 1.7 PID CDC42 PATHWAY CDC42 signaling events
0.0 1.2 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.6 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.2 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.3 PID RHOA PATHWAY RhoA signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 3.5 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.1 1.0 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 2.2 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1 0.1 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 1.5 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 1.6 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 2.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 2.3 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.1 0.3 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.9 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 1.4 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 4.1 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 1.4 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.5 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.7 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.6 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.8 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.1 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 0.2 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 1.7 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.6 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 2.4 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.1 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.4 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.2 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.9 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.7 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 1.7 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.9 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.0 0.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 1.1 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.2 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.1 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 4.6 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.2 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.1 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.6 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.3 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.2 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1