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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for MAF_NRL
Z-value: 0.84
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Transcription factors associated with MAF_NRL
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| MAF | hg19_v2_chr16_-_79634595_79634620 | 0.46 | 3.6e-01 | Click! |
| NRL | hg19_v2_chr14_-_24584138_24584223 | 0.42 | 4.1e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr11_-_2924720 Show fit | 0.66 |
ENST00000455942.2
|
solute carrier family 22 (organic cation transporter), member 18 antisense |
|
| chr20_-_18774614 Show fit | 0.43 |
ENST00000412553.1
|
long intergenic non-protein coding RNA 652 |
|
| chrX_-_63005405 Show fit | 0.41 |
ENST00000374878.1
ENST00000437457.2 |
Cdc42 guanine nucleotide exchange factor (GEF) 9 |
|
| chr17_-_39769005 Show fit | 0.39 |
ENST00000301653.4
ENST00000593067.1 |
keratin 16 |
|
| chr19_+_38880695 Show fit | 0.38 |
ENST00000587947.1
ENST00000338502.4 |
sprouty-related, EVH1 domain containing 3 |
|
| chr11_-_45928830 Show fit | 0.37 |
ENST00000449465.1
|
chromosome 11 open reading frame 94 |
|
| chr20_-_35274548 Show fit | 0.37 |
ENST00000262866.4
|
Src-like-adaptor 2 |
|
| chr22_+_42196666 Show fit | 0.35 |
ENST00000402061.3
ENST00000255784.5 |
coiled-coil domain containing 134 |
|
| chr22_-_31688381 Show fit | 0.35 |
ENST00000487265.2
|
phosphoinositide-3-kinase interacting protein 1 |
|
| chr14_-_57197224 Show fit | 0.35 |
ENST00000554597.1
ENST00000556696.1 |
Uncharacterized protein |
Network of associatons between targets according to the STRING database.
First level regulatory network of MAF_NRL
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.6 | GO:2000194 | regulation of female gonad development(GO:2000194) |
| 0.1 | 0.5 | GO:0043553 | negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) |
| 0.0 | 0.5 | GO:0051546 | keratinocyte migration(GO:0051546) |
| 0.0 | 0.4 | GO:0050849 | negative regulation of calcium-mediated signaling(GO:0050849) |
| 0.0 | 0.4 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.0 | 0.4 | GO:0007130 | synaptonemal complex assembly(GO:0007130) |
| 0.1 | 0.3 | GO:0031448 | regulation of twitch skeletal muscle contraction(GO:0014724) regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448) |
| 0.0 | 0.3 | GO:2000809 | positive regulation of synaptic vesicle clustering(GO:2000809) |
| 0.0 | 0.3 | GO:0018317 | protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406) |
| 0.0 | 0.3 | GO:0006477 | protein sulfation(GO:0006477) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.5 | GO:0030056 | hemidesmosome(GO:0030056) |
| 0.0 | 0.4 | GO:0031095 | platelet dense tubular network membrane(GO:0031095) |
| 0.0 | 0.3 | GO:0045323 | interleukin-1 receptor complex(GO:0045323) |
| 0.0 | 0.2 | GO:0070931 | Golgi-associated vesicle lumen(GO:0070931) |
| 0.0 | 0.2 | GO:0030905 | retromer, tubulation complex(GO:0030905) |
| 0.0 | 0.2 | GO:0000172 | ribonuclease MRP complex(GO:0000172) |
| 0.0 | 0.2 | GO:0005916 | fascia adherens(GO:0005916) |
| 0.0 | 0.2 | GO:0097433 | dense body(GO:0097433) |
| 0.0 | 0.1 | GO:0072517 | viral factory(GO:0039713) cytoplasmic viral factory(GO:0039714) host cell viral assembly compartment(GO:0072517) |
| 0.0 | 0.1 | GO:0030689 | Noc complex(GO:0030689) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 0.5 | GO:0036313 | phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313) |
| 0.0 | 0.5 | GO:0030506 | ankyrin binding(GO:0030506) |
| 0.0 | 0.4 | GO:0000030 | mannosyltransferase activity(GO:0000030) |
| 0.1 | 0.3 | GO:0005150 | interleukin-1, Type I receptor binding(GO:0005150) |
| 0.0 | 0.3 | GO:0050119 | N-acetylglucosamine deacetylase activity(GO:0050119) |
| 0.0 | 0.3 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 0.0 | 0.2 | GO:1990460 | leptin receptor binding(GO:1990460) |
| 0.0 | 0.2 | GO:0004345 | glucose-6-phosphate dehydrogenase activity(GO:0004345) |
| 0.0 | 0.2 | GO:0004614 | phosphoglucomutase activity(GO:0004614) |
| 0.0 | 0.2 | GO:0008798 | beta-aspartyl-peptidase activity(GO:0008798) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | SA CASPASE CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | REACTOME GABA A RECEPTOR ACTIVATION | Genes involved in GABA A receptor activation |
| 0.0 | 0.1 | REACTOME BINDING AND ENTRY OF HIV VIRION | Genes involved in Binding and entry of HIV virion |