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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for MAF_NRL

Z-value: 0.84

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Transcription factors associated with MAF_NRL

Gene Symbol Gene ID Gene Info
MAF
ENSG00000178573.6 MAF bZIP transcription factor
NRL
ENSG00000129535.8 neural retina leucine zipper

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MAFhg19_v2_chr16_-_79634595_796346200.463.6e-01Click!
NRLhg19_v2_chr14_-_24584138_245842230.424.1e-01Click!

Activity profile of MAF_NRL motif

Sorted Z-values of MAF_NRL motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_2924720 0.66 ENST00000455942.2
SLC22A18AS
solute carrier family 22 (organic cation transporter), member 18 antisense
chr20_-_18774614 0.43 ENST00000412553.1
LINC00652
long intergenic non-protein coding RNA 652
chrX_-_63005405 0.41 ENST00000374878.1
ENST00000437457.2
ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr17_-_39769005 0.39 ENST00000301653.4
ENST00000593067.1
KRT16
keratin 16
chr19_+_38880695 0.38 ENST00000587947.1
ENST00000338502.4
SPRED3
sprouty-related, EVH1 domain containing 3
chr11_-_45928830 0.37 ENST00000449465.1
C11orf94
chromosome 11 open reading frame 94
chr20_-_35274548 0.37 ENST00000262866.4
SLA2
Src-like-adaptor 2
chr22_+_42196666 0.35 ENST00000402061.3
ENST00000255784.5
CCDC134
coiled-coil domain containing 134
chr22_-_31688381 0.35 ENST00000487265.2
PIK3IP1
phosphoinositide-3-kinase interacting protein 1
chr14_-_57197224 0.35 ENST00000554597.1
ENST00000556696.1
RP11-1085N6.3
Uncharacterized protein
chr7_-_35013217 0.35 ENST00000446375.1
DPY19L1
dpy-19-like 1 (C. elegans)
chr5_-_159766528 0.34 ENST00000505287.2
CCNJL
cyclin J-like
chr16_+_77246337 0.34 ENST00000563157.1
SYCE1L
synaptonemal complex central element protein 1-like
chr11_-_2924970 0.30 ENST00000533594.1
SLC22A18AS
solute carrier family 22 (organic cation transporter), member 18 antisense
chr11_-_1330834 0.28 ENST00000525159.1
ENST00000317204.6
ENST00000542915.1
ENST00000527938.1
ENST00000530541.1
ENST00000263646.7
TOLLIP
toll interacting protein
chr16_+_777739 0.28 ENST00000563792.1
HAGHL
hydroxyacylglutathione hydrolase-like
chr4_+_22999152 0.27 ENST00000511453.1
RP11-412P11.1
RP11-412P11.1
chr8_-_145018905 0.27 ENST00000398774.2
PLEC
plectin
chr17_+_635786 0.27 ENST00000572018.1
ENST00000301324.8
FAM57A
family with sequence similarity 57, member A
chr16_-_28550320 0.26 ENST00000395641.2
NUPR1
nuclear protein, transcriptional regulator, 1
chr1_-_221509638 0.26 ENST00000439004.1
RP11-421L10.1
RP11-421L10.1
chr16_-_28550348 0.26 ENST00000324873.6
NUPR1
nuclear protein, transcriptional regulator, 1
chr11_+_64808675 0.25 ENST00000529996.1
SAC3D1
SAC3 domain containing 1
chr15_+_64428529 0.25 ENST00000560861.1
SNX1
sorting nexin 1
chr3_+_188664988 0.25 ENST00000433971.1
TPRG1
tumor protein p63 regulated 1
chr20_-_48530230 0.24 ENST00000422556.1
SPATA2
spermatogenesis associated 2
chr17_+_7341586 0.24 ENST00000575235.1
FGF11
fibroblast growth factor 11
chrX_-_153775426 0.23 ENST00000393562.2
G6PD
glucose-6-phosphate dehydrogenase
chr17_+_7253667 0.23 ENST00000570504.1
ENST00000574499.1
ACAP1
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chr9_+_70971815 0.23 ENST00000396392.1
ENST00000396396.1
PGM5
phosphoglucomutase 5
chr18_-_25616519 0.22 ENST00000399380.3
CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr1_+_24645915 0.22 ENST00000350501.5
GRHL3
grainyhead-like 3 (Drosophila)
chr8_+_145438870 0.21 ENST00000527931.1
FAM203B
family with sequence similarity 203, member B
chr5_-_156390230 0.21 ENST00000407087.3
ENST00000274532.2
TIMD4
T-cell immunoglobulin and mucin domain containing 4
chr16_+_85936295 0.21 ENST00000563180.1
ENST00000564617.1
ENST00000564803.1
IRF8
interferon regulatory factor 8
chr19_+_7445850 0.21 ENST00000593531.1
CTD-2207O23.3
Rho guanine nucleotide exchange factor 18
chr6_-_33297013 0.20 ENST00000453407.1
DAXX
death-domain associated protein
chr7_+_99816859 0.20 ENST00000317271.2
PVRIG
poliovirus receptor related immunoglobulin domain containing
chr21_-_16135411 0.20 ENST00000435315.2
AF127936.5
AF127936.5
chr14_+_77787227 0.20 ENST00000216465.5
ENST00000361389.4
ENST00000554279.1
ENST00000557639.1
ENST00000349555.3
ENST00000556627.1
ENST00000557053.1
GSTZ1
glutathione S-transferase zeta 1
chr1_-_149783914 0.19 ENST00000369167.1
ENST00000427880.2
ENST00000545683.1
HIST2H2BF
histone cluster 2, H2bf
chr16_+_28889801 0.19 ENST00000395503.4
ATP2A1
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr9_-_92020841 0.19 ENST00000433650.1
SEMA4D
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
chr1_-_1293904 0.19 ENST00000309212.6
ENST00000342753.4
ENST00000445648.2
MXRA8
matrix-remodelling associated 8
chr14_+_100485712 0.18 ENST00000544450.2
EVL
Enah/Vasp-like
chr17_-_73874654 0.18 ENST00000254816.2
TRIM47
tripartite motif containing 47
chr17_-_74489215 0.18 ENST00000585701.1
ENST00000591192.1
ENST00000589526.1
RHBDF2
rhomboid 5 homolog 2 (Drosophila)
chr11_-_133826852 0.17 ENST00000533871.2
ENST00000321016.8
IGSF9B
immunoglobulin superfamily, member 9B
chr7_+_127527965 0.17 ENST00000486037.1
SND1
staphylococcal nuclease and tudor domain containing 1
chr5_-_179227540 0.17 ENST00000520875.1
MGAT4B
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
chr16_-_4664382 0.17 ENST00000591113.1
UBALD1
UBA-like domain containing 1
chr16_+_83986827 0.17 ENST00000393306.1
ENST00000565123.1
OSGIN1
oxidative stress induced growth inhibitor 1
chr3_-_117716418 0.17 ENST00000484092.1
RP11-384F7.2
RP11-384F7.2
chr17_+_635652 0.17 ENST00000308278.8
FAM57A
family with sequence similarity 57, member A
chr1_-_45253377 0.16 ENST00000372207.3
BEST4
bestrophin 4
chr5_+_149877334 0.16 ENST00000523767.1
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr15_-_75248954 0.16 ENST00000499788.2
RPP25
ribonuclease P/MRP 25kDa subunit
chr19_+_50094866 0.16 ENST00000418929.2
PRR12
proline rich 12
chr3_+_193853927 0.16 ENST00000232424.3
HES1
hes family bHLH transcription factor 1
chr1_-_110306526 0.16 ENST00000361965.4
ENST00000361852.4
EPS8L3
EPS8-like 3
chr16_-_70712229 0.16 ENST00000562883.2
MTSS1L
metastasis suppressor 1-like
chr19_+_9361606 0.15 ENST00000456448.1
OR7E24
olfactory receptor, family 7, subfamily E, member 24
chr9_-_125240235 0.15 ENST00000259357.2
OR1J1
olfactory receptor, family 1, subfamily J, member 1
chr15_-_82338460 0.15 ENST00000558133.1
ENST00000329713.4
MEX3B
mex-3 RNA binding family member B
chr1_-_146082633 0.15 ENST00000605317.1
ENST00000604938.1
ENST00000339388.5
NBPF11
neuroblastoma breakpoint family, member 11
chr7_+_66800928 0.15 ENST00000430244.1
RP11-166O4.5
RP11-166O4.5
chr11_-_124632179 0.15 ENST00000278927.5
ENST00000442070.2
ENST00000444566.1
ENST00000435477.1
ESAM
endothelial cell adhesion molecule
chr14_-_77787198 0.15 ENST00000261534.4
POMT2
protein-O-mannosyltransferase 2
chr11_-_6495101 0.14 ENST00000528227.1
ENST00000359518.3
ENST00000345851.3
ENST00000537602.1
TRIM3
tripartite motif containing 3
chr9_-_97356075 0.14 ENST00000375337.3
FBP2
fructose-1,6-bisphosphatase 2
chr2_-_97536490 0.14 ENST00000449330.1
SEMA4C
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr3_-_138553779 0.14 ENST00000461451.1
PIK3CB
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
chr2_-_220083076 0.14 ENST00000295750.4
ABCB6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr2_+_87755054 0.14 ENST00000423846.1
LINC00152
long intergenic non-protein coding RNA 152
chr19_-_7812446 0.14 ENST00000394173.4
ENST00000301357.8
CD209
CD209 molecule
chr11_-_119599794 0.14 ENST00000264025.3
PVRL1
poliovirus receptor-related 1 (herpesvirus entry mediator C)
chr16_+_2802623 0.13 ENST00000576924.1
ENST00000575009.1
ENST00000576415.1
ENST00000571378.1
SRRM2
serine/arginine repetitive matrix 2
chr6_+_160693591 0.13 ENST00000419196.1
RP1-276N6.2
RP1-276N6.2
chr16_+_28889703 0.13 ENST00000357084.3
ATP2A1
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr21_+_35014829 0.13 ENST00000451686.1
ITSN1
intersectin 1 (SH3 domain protein)
chr3_-_151176497 0.13 ENST00000282466.3
IGSF10
immunoglobulin superfamily, member 10
chr16_+_12059091 0.13 ENST00000562385.1
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr17_-_38520067 0.13 ENST00000337376.4
ENST00000578689.1
GJD3
gap junction protein, delta 3, 31.9kDa
chr16_-_1429627 0.13 ENST00000248104.7
UNKL
unkempt family zinc finger-like
chr9_+_132597722 0.13 ENST00000372429.3
ENST00000315480.4
ENST00000358355.1
USP20
ubiquitin specific peptidase 20
chrX_-_49056635 0.13 ENST00000472598.1
ENST00000538567.1
ENST00000479808.1
ENST00000263233.4
SYP
synaptophysin
chr14_+_23067166 0.13 ENST00000216327.6
ENST00000542041.1
ABHD4
abhydrolase domain containing 4
chr20_-_48099182 0.13 ENST00000371741.4
KCNB1
potassium voltage-gated channel, Shab-related subfamily, member 1
chr4_+_154125565 0.13 ENST00000338700.5
TRIM2
tripartite motif containing 2
chr16_-_4164027 0.12 ENST00000572288.1
ADCY9
adenylate cyclase 9
chr12_+_48178706 0.12 ENST00000599515.1
AC004466.1
Uncharacterized protein
chr19_-_55895966 0.12 ENST00000444469.3
TMEM238
transmembrane protein 238
chrX_+_70364667 0.12 ENST00000536169.1
ENST00000395855.2
ENST00000374051.3
ENST00000358741.3
NLGN3
neuroligin 3
chr17_+_1666108 0.12 ENST00000570731.1
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr14_+_93118813 0.12 ENST00000556418.1
RIN3
Ras and Rab interactor 3
chr22_-_31688431 0.12 ENST00000402249.3
ENST00000443175.1
ENST00000215912.5
ENST00000441972.1
PIK3IP1
phosphoinositide-3-kinase interacting protein 1
chr5_+_149877440 0.12 ENST00000518299.1
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr8_-_66474884 0.12 ENST00000520902.1
CTD-3025N20.2
CTD-3025N20.2
chr10_+_99609996 0.12 ENST00000370602.1
GOLGA7B
golgin A7 family, member B
chr9_-_16276311 0.12 ENST00000380685.1
C9orf92
chromosome 9 open reading frame 92
chr5_+_132009675 0.12 ENST00000231449.2
ENST00000350025.2
IL4
interleukin 4
chr17_+_30089454 0.12 ENST00000577970.1
RP11-805L22.3
RP11-805L22.3
chr1_+_24646263 0.12 ENST00000524724.1
GRHL3
grainyhead-like 3 (Drosophila)
chr22_+_31489344 0.12 ENST00000404574.1
SMTN
smoothelin
chr12_+_47610315 0.12 ENST00000548348.1
ENST00000549500.1
PCED1B
PC-esterase domain containing 1B
chr12_+_32260085 0.12 ENST00000548411.1
ENST00000281474.5
ENST00000551086.1
BICD1
bicaudal D homolog 1 (Drosophila)
chr17_-_54893250 0.12 ENST00000397862.2
C17orf67
chromosome 17 open reading frame 67
chr16_+_3254247 0.12 ENST00000304646.2
OR1F1
olfactory receptor, family 1, subfamily F, member 1
chr14_+_23067146 0.11 ENST00000428304.2
ABHD4
abhydrolase domain containing 4
chr4_-_168155577 0.11 ENST00000541354.1
ENST00000509854.1
ENST00000512681.1
ENST00000421836.2
ENST00000510741.1
ENST00000510403.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr20_+_42187608 0.11 ENST00000373100.1
SGK2
serum/glucocorticoid regulated kinase 2
chr11_-_117166201 0.11 ENST00000510915.1
BACE1
beta-site APP-cleaving enzyme 1
chr2_-_74757066 0.11 ENST00000377526.3
AUP1
ancient ubiquitous protein 1
chr8_-_145025044 0.11 ENST00000322810.4
PLEC
plectin
chr22_-_38240412 0.11 ENST00000215941.4
ANKRD54
ankyrin repeat domain 54
chr19_-_46285736 0.11 ENST00000291270.4
ENST00000447742.2
ENST00000354227.5
DMPK
dystrophia myotonica-protein kinase
chr2_-_26251481 0.11 ENST00000599234.1
AC013449.1
Uncharacterized protein
chr5_+_42756903 0.11 ENST00000361970.5
ENST00000388827.4
CCDC152
coiled-coil domain containing 152
chr21_-_36421401 0.11 ENST00000486278.2
RUNX1
runt-related transcription factor 1
chr1_+_161691353 0.11 ENST00000367948.2
FCRLB
Fc receptor-like B
chr5_+_174151536 0.11 ENST00000239243.6
ENST00000507785.1
MSX2
msh homeobox 2
chr16_-_58004992 0.11 ENST00000564448.1
ENST00000251102.8
ENST00000311183.4
CNGB1
cyclic nucleotide gated channel beta 1
chr12_+_132628963 0.11 ENST00000330579.1
NOC4L
nucleolar complex associated 4 homolog (S. cerevisiae)
chr2_+_101591314 0.11 ENST00000450763.1
NPAS2
neuronal PAS domain protein 2
chr2_-_219134343 0.11 ENST00000447885.1
ENST00000420660.1
AAMP
angio-associated, migratory cell protein
chr14_+_57735636 0.11 ENST00000556995.1
AP5M1
adaptor-related protein complex 5, mu 1 subunit
chr2_+_74757050 0.11 ENST00000352222.3
ENST00000437202.1
HTRA2
HtrA serine peptidase 2
chr11_+_20044096 0.11 ENST00000533917.1
NAV2
neuron navigator 2
chr3_-_150264272 0.11 ENST00000491660.1
ENST00000487153.1
ENST00000239944.2
SERP1
stress-associated endoplasmic reticulum protein 1
chr3_-_47934234 0.11 ENST00000420772.2
MAP4
microtubule-associated protein 4
chr1_+_6105974 0.11 ENST00000378083.3
KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr20_-_22559211 0.10 ENST00000564492.1
LINC00261
long intergenic non-protein coding RNA 261
chr1_-_1297157 0.10 ENST00000477278.2
MXRA8
matrix-remodelling associated 8
chr17_+_50939459 0.10 ENST00000412360.1
AC102948.2
Uncharacterized protein
chr10_+_24755416 0.10 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217
KIAA1217
chr3_-_47484661 0.10 ENST00000495603.2
SCAP
SREBF chaperone
chr12_+_53662073 0.10 ENST00000553219.1
ENST00000257934.4
ESPL1
extra spindle pole bodies homolog 1 (S. cerevisiae)
chr7_+_2695726 0.10 ENST00000429448.1
TTYH3
tweety family member 3
chr7_+_151791074 0.10 ENST00000447796.1
GALNT11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr16_+_475599 0.10 ENST00000262305.4
ENST00000457159.1
RAB11FIP3
RAB11 family interacting protein 3 (class II)
chr16_+_85204882 0.10 ENST00000574293.1
CTC-786C10.1
CTC-786C10.1
chr15_-_72514866 0.10 ENST00000562997.1
PKM
pyruvate kinase, muscle
chr3_+_195447738 0.10 ENST00000447234.2
ENST00000320736.6
ENST00000436408.1
MUC20
mucin 20, cell surface associated
chr18_+_18943554 0.10 ENST00000580732.2
GREB1L
growth regulation by estrogen in breast cancer-like
chr7_+_95401877 0.10 ENST00000524053.1
ENST00000324972.6
ENST00000537881.1
ENST00000437599.1
ENST00000359388.4
ENST00000413338.1
DYNC1I1
dynein, cytoplasmic 1, intermediate chain 1
chr1_-_150978953 0.10 ENST00000493834.2
FAM63A
family with sequence similarity 63, member A
chr12_+_51318513 0.10 ENST00000332160.4
METTL7A
methyltransferase like 7A
chr11_+_107461948 0.10 ENST00000265840.7
ENST00000443271.2
ELMOD1
ELMO/CED-12 domain containing 1
chr2_-_179914760 0.10 ENST00000420890.2
ENST00000409284.1
ENST00000443758.1
ENST00000446116.1
CCDC141
coiled-coil domain containing 141
chr18_-_73967160 0.10 ENST00000579714.1
RP11-94B19.7
RP11-94B19.7
chr1_+_43148059 0.10 ENST00000321358.7
ENST00000332220.6
YBX1
Y box binding protein 1
chr20_-_45530365 0.10 ENST00000414085.1
RP11-323C15.2
RP11-323C15.2
chr20_+_1246908 0.10 ENST00000381873.3
ENST00000381867.1
SNPH
syntaphilin
chr4_-_99578776 0.10 ENST00000515287.1
TSPAN5
tetraspanin 5
chr4_+_39408470 0.10 ENST00000257408.4
KLB
klotho beta
chr6_-_656963 0.10 ENST00000380907.2
HUS1B
HUS1 checkpoint homolog b (S. pombe)
chr16_+_2510081 0.10 ENST00000361837.4
ENST00000569496.1
ENST00000567489.1
ENST00000563531.1
ENST00000483320.1
C16orf59
chromosome 16 open reading frame 59
chr6_+_32936942 0.10 ENST00000496118.2
BRD2
bromodomain containing 2
chr17_+_7836398 0.09 ENST00000565740.1
CNTROB
centrobin, centrosomal BRCA2 interacting protein
chr16_-_1429674 0.09 ENST00000403703.1
ENST00000397464.1
ENST00000402641.2
UNKL
unkempt family zinc finger-like
chr17_+_72667239 0.09 ENST00000402449.4
RAB37
RAB37, member RAS oncogene family
chr10_+_71389983 0.09 ENST00000373279.4
C10orf35
chromosome 10 open reading frame 35
chr17_-_74163159 0.09 ENST00000591615.1
RNF157
ring finger protein 157
chr8_+_145065705 0.09 ENST00000533044.1
GRINA
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr16_+_67261008 0.09 ENST00000304800.9
ENST00000563953.1
ENST00000565201.1
TMEM208
transmembrane protein 208
chr16_+_28962128 0.09 ENST00000564978.1
ENST00000320805.4
NFATC2IP
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein
chr14_+_101295948 0.09 ENST00000452514.2
MEG3
maternally expressed 3 (non-protein coding)
chr19_-_36545649 0.09 ENST00000292894.1
THAP8
THAP domain containing 8
chr6_+_32936353 0.09 ENST00000374825.4
BRD2
bromodomain containing 2
chr12_+_50366620 0.09 ENST00000315520.5
AQP6
aquaporin 6, kidney specific
chr22_-_45609315 0.09 ENST00000443310.3
ENST00000424508.1
KIAA0930
KIAA0930
chr4_+_8201091 0.09 ENST00000382521.3
ENST00000245105.3
ENST00000457650.2
ENST00000539824.1
SH3TC1
SH3 domain and tetratricopeptide repeats 1
chr1_-_110306562 0.09 ENST00000369805.3
EPS8L3
EPS8-like 3
chr15_-_72564906 0.09 ENST00000566844.1
PARP6
poly (ADP-ribose) polymerase family, member 6
chr16_-_68404908 0.09 ENST00000574662.1
SMPD3
sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
chr5_+_175298674 0.09 ENST00000514150.1
CPLX2
complexin 2
chr17_-_3495644 0.09 ENST00000310522.5
ENST00000425167.2
ENST00000576351.1
TRPV1
transient receptor potential cation channel, subfamily V, member 1
chr11_+_12108410 0.09 ENST00000527997.1
RP13-631K18.5
RP13-631K18.5
chr11_+_64808368 0.09 ENST00000531072.1
ENST00000398846.1
SAC3D1
SAC3 domain containing 1
chr17_+_55183261 0.09 ENST00000576295.1
AKAP1
A kinase (PRKA) anchor protein 1
chr3_+_171844762 0.09 ENST00000443501.1
FNDC3B
fibronectin type III domain containing 3B
chr4_+_160188306 0.09 ENST00000510510.1
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr1_+_39876151 0.09 ENST00000530275.1
KIAA0754
KIAA0754
chr3_-_53878644 0.09 ENST00000481668.1
ENST00000467802.1
CHDH
choline dehydrogenase
chr16_-_67700594 0.09 ENST00000602644.1
ENST00000243878.4
ENKD1
enkurin domain containing 1
chr9_-_140351928 0.09 ENST00000339554.3
NSMF
NMDA receptor synaptonuclear signaling and neuronal migration factor
chr19_-_55628700 0.09 ENST00000592993.1
PPP1R12C
protein phosphatase 1, regulatory subunit 12C
chr2_+_74881432 0.09 ENST00000453930.1
SEMA4F
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
chr9_+_125796806 0.09 ENST00000373642.1
GPR21
G protein-coupled receptor 21
chr22_-_21984282 0.09 ENST00000398873.3
ENST00000292778.6
YDJC
YdjC homolog (bacterial)
chr2_-_219134822 0.09 ENST00000444053.1
ENST00000248450.4
AAMP
angio-associated, migratory cell protein
chr19_-_46088068 0.08 ENST00000263275.4
ENST00000323060.3
OPA3
optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
chrX_+_64708615 0.08 ENST00000338957.4
ENST00000423889.3
ZC3H12B
zinc finger CCCH-type containing 12B
chr20_-_17511962 0.08 ENST00000377873.3
BFSP1
beaded filament structural protein 1, filensin
chr1_+_203256898 0.08 ENST00000433008.1
RP11-134P9.3
RP11-134P9.3
chr19_-_46145696 0.08 ENST00000588172.1
EML2
echinoderm microtubule associated protein like 2
chr13_-_47471155 0.08 ENST00000543956.1
ENST00000542664.1
HTR2A
5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
chr4_-_57976544 0.08 ENST00000295666.4
ENST00000537922.1
IGFBP7
insulin-like growth factor binding protein 7
chr6_-_24489842 0.08 ENST00000230036.1
GPLD1
glycosylphosphatidylinositol specific phospholipase D1
chr11_-_118122996 0.08 ENST00000525386.1
ENST00000527472.1
ENST00000278949.4
MPZL3
myelin protein zero-like 3

Network of associatons between targets according to the STRING database.

First level regulatory network of MAF_NRL

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0031448 regulation of twitch skeletal muscle contraction(GO:0014724) regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.1 0.5 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 0.2 GO:0072738 response to diamide(GO:0072737) cellular response to diamide(GO:0072738)
0.1 0.2 GO:0021919 BMP signaling pathway involved in spinal cord dorsal/ventral patterning(GO:0021919)
0.1 0.2 GO:2000981 negative regulation of auditory receptor cell differentiation(GO:0045608) negative regulation of mechanoreceptor differentiation(GO:0045632) negative regulation of inner ear receptor cell differentiation(GO:2000981)
0.0 0.2 GO:0046968 peptide antigen transport(GO:0046968)
0.0 0.1 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.0 0.2 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.3 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 0.1 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.2 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.0 0.2 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.1 GO:1900737 regulation of proteinase activated receptor activity(GO:1900276) negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900737)
0.0 0.1 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.0 0.2 GO:0010693 negative regulation of alkaline phosphatase activity(GO:0010693)
0.0 0.1 GO:0051795 positive regulation of catagen(GO:0051795) activation of meiosis(GO:0090427)
0.0 0.1 GO:0043311 regulation of eosinophil degranulation(GO:0043309) positive regulation of eosinophil degranulation(GO:0043311) regulation of eosinophil activation(GO:1902566) positive regulation of eosinophil activation(GO:1902568)
0.0 0.1 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.0 0.6 GO:2000194 regulation of female gonad development(GO:2000194)
0.0 0.1 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.0 0.1 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.0 0.3 GO:0018317 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.1 GO:0006624 vacuolar protein processing(GO:0006624)
0.0 0.0 GO:0035995 detection of muscle stretch(GO:0035995)
0.0 0.1 GO:0071288 cellular response to mercury ion(GO:0071288) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 0.1 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0 0.1 GO:2000980 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.1 GO:0061727 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.1 GO:1990258 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.0 0.1 GO:0061386 closure of optic fissure(GO:0061386)
0.0 0.1 GO:1904245 regulation of polynucleotide adenylyltransferase activity(GO:1904245)
0.0 0.1 GO:0046041 ITP metabolic process(GO:0046041)
0.0 0.5 GO:0051546 keratinocyte migration(GO:0051546)
0.0 0.1 GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process(GO:0046901)
0.0 0.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.0 0.3 GO:0006477 protein sulfation(GO:0006477)
0.0 0.1 GO:0003335 corneocyte development(GO:0003335)
0.0 0.0 GO:0060008 Sertoli cell differentiation(GO:0060008) Sertoli cell development(GO:0060009)
0.0 0.1 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.0 0.1 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.1 GO:1901594 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.0 0.0 GO:1990535 neuron projection maintenance(GO:1990535)
0.0 0.1 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.1 GO:0086092 regulation of the force of heart contraction by cardiac conduction(GO:0086092)
0.0 0.1 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.0 0.1 GO:0031455 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.0 0.0 GO:0036119 response to platelet-derived growth factor(GO:0036119) cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.0 0.1 GO:0021816 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.0 0.1 GO:0060380 regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381)
0.0 0.1 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.1 GO:0051389 inactivation of MAPKK activity(GO:0051389)
0.0 0.1 GO:1903028 positive regulation of opsonization(GO:1903028)
0.0 0.2 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.1 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.2 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0 0.0 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0 0.2 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.4 GO:0050849 negative regulation of calcium-mediated signaling(GO:0050849)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.0 GO:0048627 myoblast development(GO:0048627)
0.0 0.0 GO:0060029 convergent extension involved in organogenesis(GO:0060029)
0.0 0.0 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.0 0.3 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.2 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.3 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 0.1 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.0 0.1 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.2 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.1 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.2 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.2 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.4 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.1 GO:0051414 response to cortisol(GO:0051414)
0.0 0.1 GO:0021564 vagus nerve development(GO:0021564)
0.0 0.1 GO:1904685 positive regulation of metalloendopeptidase activity(GO:1904685)
0.0 0.2 GO:0010737 protein kinase A signaling(GO:0010737) regulation of protein kinase A signaling(GO:0010738)
0.0 0.1 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.1 GO:0001927 exocyst assembly(GO:0001927)
0.0 0.1 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.0 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.3 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.0 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.0 0.0 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.0 0.1 GO:0010728 positive regulation of hydrogen peroxide metabolic process(GO:0010726) regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.1 GO:0044800 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.1 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.1 GO:0033131 regulation of glucokinase activity(GO:0033131) regulation of hexokinase activity(GO:1903299)
0.0 0.1 GO:0097398 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.1 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.1 GO:2001222 regulation of neuron migration(GO:2001222)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.1 GO:0072517 viral factory(GO:0039713) cytoplasmic viral factory(GO:0039714) host cell viral assembly compartment(GO:0072517)
0.0 0.2 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.0 0.1 GO:0030689 Noc complex(GO:0030689)
0.0 0.2 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.1 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 0.1 GO:1902912 pyruvate kinase complex(GO:1902912)
0.0 0.2 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.1 GO:1990031 pinceau fiber(GO:1990031)
0.0 0.1 GO:0031523 Myb complex(GO:0031523)
0.0 0.5 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.0 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 0.0 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.4 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.2 GO:0005916 fascia adherens(GO:0005916)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.0 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.1 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.1 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.2 GO:0097433 dense body(GO:0097433)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 0.3 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.0 0.2 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.1 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0 0.1 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.0 0.2 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 0.3 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.2 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.1 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.0 0.1 GO:0036009 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.0 0.2 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.1 GO:0004326 tetrahydrofolylpolyglutamate synthase activity(GO:0004326) dihydrofolate synthase activity(GO:0008841)
0.0 0.1 GO:0004766 spermidine synthase activity(GO:0004766)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.1 GO:0019862 IgA binding(GO:0019862)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.0 0.1 GO:0086040 sodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086040)
0.0 0.1 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.1 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.1 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.1 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.2 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0 0.0 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.1 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.0 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0 0.0 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.0 0.0 GO:0030572 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.0 0.1 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.0 0.1 GO:0031386 protein tag(GO:0031386)
0.0 0.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.2 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.4 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.1 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.0 0.0 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.0 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.0 0.5 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.3 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation