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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for LMX1B_MNX1_RAX2

Z-value: 0.51

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Transcription factors associated with LMX1B_MNX1_RAX2

Gene Symbol Gene ID Gene Info
LMX1B
ENSG00000136944.13 LIM homeobox transcription factor 1 beta
MNX1
ENSG00000130675.10 motor neuron and pancreas homeobox 1
RAX2
ENSG00000173976.11 retina and anterior neural fold homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
LMX1Bhg19_v2_chr9_+_129376722_129376748-0.911.3e-02Click!
MNX1hg19_v2_chr7_-_156803329_156803362-0.711.1e-01Click!
RAX2hg19_v2_chr19_-_3772209_37722360.532.8e-01Click!

Activity profile of LMX1B_MNX1_RAX2 motif

Sorted Z-values of LMX1B_MNX1_RAX2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chrM_+_10464 0.93 ENST00000361335.1
MT-ND4L
mitochondrially encoded NADH dehydrogenase 4L
chr4_-_36245561 0.79 ENST00000506189.1
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr12_+_28410128 0.58 ENST00000381259.1
ENST00000381256.1
CCDC91
coiled-coil domain containing 91
chrM_+_10758 0.57 ENST00000361381.2
MT-ND4
mitochondrially encoded NADH dehydrogenase 4
chr14_-_51027838 0.45 ENST00000555216.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr16_+_53133070 0.45 ENST00000565832.1
CHD9
chromodomain helicase DNA binding protein 9
chr7_-_92777606 0.44 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L
sterile alpha motif domain containing 9-like
chr7_+_77428066 0.44 ENST00000422959.2
ENST00000307305.8
ENST00000424760.1
PHTF2
putative homeodomain transcription factor 2
chr1_-_101360331 0.40 ENST00000416479.1
ENST00000370113.3
EXTL2
exostosin-like glycosyltransferase 2
chr7_+_77428149 0.38 ENST00000415251.2
ENST00000275575.7
PHTF2
putative homeodomain transcription factor 2
chr2_+_172309634 0.37 ENST00000339506.3
DCAF17
DDB1 and CUL4 associated factor 17
chr2_-_61697862 0.32 ENST00000398571.2
USP34
ubiquitin specific peptidase 34
chr12_-_94673956 0.32 ENST00000551941.1
RP11-1105G2.3
Uncharacterized protein
chr6_+_105404899 0.32 ENST00000345080.4
LIN28B
lin-28 homolog B (C. elegans)
chr4_+_26324474 0.31 ENST00000514675.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr1_-_101360374 0.30 ENST00000535414.1
EXTL2
exostosin-like glycosyltransferase 2
chr6_+_130339710 0.29 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chr4_+_169013666 0.28 ENST00000359299.3
ANXA10
annexin A10
chrM_+_10053 0.26 ENST00000361227.2
MT-ND3
mitochondrially encoded NADH dehydrogenase 3
chr2_-_136678123 0.26 ENST00000422708.1
DARS
aspartyl-tRNA synthetase
chr7_-_77427676 0.25 ENST00000257663.3
TMEM60
transmembrane protein 60
chr13_-_86373536 0.23 ENST00000400286.2
SLITRK6
SLIT and NTRK-like family, member 6
chrM_+_7586 0.22 ENST00000361739.1
MT-CO2
mitochondrially encoded cytochrome c oxidase II
chr6_-_32157947 0.21 ENST00000375050.4
PBX2
pre-B-cell leukemia homeobox 2
chr2_+_216946589 0.20 ENST00000433112.1
ENST00000454545.1
ENST00000437356.2
ENST00000295658.4
ENST00000455479.1
ENST00000406027.2
TMEM169
transmembrane protein 169
chr1_-_242612726 0.19 ENST00000459864.1
PLD5
phospholipase D family, member 5
chr12_+_20963647 0.18 ENST00000381545.3
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr11_-_31531121 0.18 ENST00000532287.1
ENST00000526776.1
ENST00000534812.1
ENST00000529749.1
ENST00000278200.1
ENST00000530023.1
ENST00000533642.1
IMMP1L
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr5_-_126409159 0.17 ENST00000607731.1
ENST00000535381.1
ENST00000296662.5
ENST00000509733.3
C5orf63
chromosome 5 open reading frame 63
chr12_+_81110684 0.17 ENST00000228644.3
MYF5
myogenic factor 5
chr14_+_67831576 0.17 ENST00000555876.1
EIF2S1
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr17_-_39203519 0.16 ENST00000542137.1
ENST00000391419.3
KRTAP2-1
keratin associated protein 2-1
chrM_+_14741 0.16 ENST00000361789.2
MT-CYB
mitochondrially encoded cytochrome b
chr3_-_78719376 0.16 ENST00000495961.1
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chrX_-_106243451 0.16 ENST00000355610.4
ENST00000535534.1
MORC4
MORC family CW-type zinc finger 4
chr19_+_50016610 0.15 ENST00000596975.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr5_-_24645078 0.15 ENST00000264463.4
CDH10
cadherin 10, type 2 (T2-cadherin)
chr17_-_38821373 0.15 ENST00000394052.3
KRT222
keratin 222
chr5_-_145562147 0.15 ENST00000545646.1
ENST00000274562.9
ENST00000510191.1
ENST00000394434.2
LARS
leucyl-tRNA synthetase
chr17_-_64225508 0.15 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr7_-_27169801 0.14 ENST00000511914.1
HOXA4
homeobox A4
chr12_+_20963632 0.14 ENST00000540853.1
ENST00000261196.2
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chrM_+_8527 0.14 ENST00000361899.2
MT-ATP6
mitochondrially encoded ATP synthase 6
chr4_-_39979576 0.14 ENST00000303538.8
ENST00000503396.1
PDS5A
PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chr17_+_56833184 0.14 ENST00000308249.2
PPM1E
protein phosphatase, Mg2+/Mn2+ dependent, 1E
chr15_+_69452959 0.14 ENST00000261858.2
GLCE
glucuronic acid epimerase
chr8_+_107460147 0.13 ENST00000442977.2
OXR1
oxidation resistance 1
chr12_-_110937351 0.13 ENST00000552130.2
VPS29
vacuolar protein sorting 29 homolog (S. cerevisiae)
chr5_+_136070614 0.13 ENST00000502421.1
CTB-1I21.1
CTB-1I21.1
chr3_-_108248169 0.13 ENST00000273353.3
MYH15
myosin, heavy chain 15
chr13_-_88323218 0.12 ENST00000436290.2
ENST00000453832.2
ENST00000606590.1
MIR4500HG
MIR4500 host gene (non-protein coding)
chrX_-_106243294 0.12 ENST00000255495.7
MORC4
MORC family CW-type zinc finger 4
chr1_-_101360205 0.12 ENST00000450240.1
EXTL2
exostosin-like glycosyltransferase 2
chrM_+_3299 0.12 ENST00000361390.2
MT-ND1
mitochondrially encoded NADH dehydrogenase 1
chr8_+_26150628 0.12 ENST00000523925.1
ENST00000315985.7
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr8_+_38831683 0.12 ENST00000302495.4
HTRA4
HtrA serine peptidase 4
chr1_+_183774240 0.11 ENST00000360851.3
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr15_+_80351910 0.11 ENST00000261749.6
ENST00000561060.1
ZFAND6
zinc finger, AN1-type domain 6
chr2_+_190541153 0.11 ENST00000313581.4
ENST00000438402.2
ENST00000431575.2
ENST00000281412.6
ANKAR
ankyrin and armadillo repeat containing
chr12_-_91546926 0.11 ENST00000550758.1
DCN
decorin
chr4_-_105416039 0.11 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr4_-_20985632 0.11 ENST00000359001.5
KCNIP4
Kv channel interacting protein 4
chr7_+_138145076 0.11 ENST00000343526.4
TRIM24
tripartite motif containing 24
chr3_-_141747950 0.11 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chrM_+_9207 0.10 ENST00000362079.2
MT-CO3
mitochondrially encoded cytochrome c oxidase III
chr3_-_33686925 0.10 ENST00000485378.2
ENST00000313350.6
ENST00000487200.1
CLASP2
cytoplasmic linker associated protein 2
chrX_-_71458802 0.10 ENST00000373657.1
ENST00000334463.3
ERCC6L
excision repair cross-complementing rodent repair deficiency, complementation group 6-like
chr1_+_180601139 0.10 ENST00000367590.4
ENST00000367589.3
XPR1
xenotropic and polytropic retrovirus receptor 1
chr2_-_207024134 0.10 ENST00000457011.1
ENST00000440274.1
ENST00000432169.1
NDUFS1
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chrX_-_46187069 0.10 ENST00000446884.1
RP1-30G7.2
RP1-30G7.2
chr18_-_33709268 0.10 ENST00000269187.5
ENST00000590986.1
ENST00000440549.2
SLC39A6
solute carrier family 39 (zinc transporter), member 6
chr19_-_7698599 0.10 ENST00000311069.5
PCP2
Purkinje cell protein 2
chrX_+_78003204 0.10 ENST00000435339.3
ENST00000514744.1
LPAR4
lysophosphatidic acid receptor 4
chr15_-_37393406 0.10 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
MEIS2
Meis homeobox 2
chr7_+_134464414 0.10 ENST00000361901.2
CALD1
caldesmon 1
chr17_-_38956205 0.09 ENST00000306658.7
KRT28
keratin 28
chrX_-_10851762 0.09 ENST00000380785.1
ENST00000380787.1
MID1
midline 1 (Opitz/BBB syndrome)
chr17_-_39150385 0.09 ENST00000391586.1
KRTAP3-3
keratin associated protein 3-3
chr8_-_25281747 0.09 ENST00000421054.2
GNRH1
gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
chr7_-_28220354 0.09 ENST00000283928.5
JAZF1
JAZF zinc finger 1
chr3_-_151034734 0.09 ENST00000260843.4
GPR87
G protein-coupled receptor 87
chr12_-_102591604 0.09 ENST00000329406.4
PMCH
pro-melanin-concentrating hormone
chrX_-_19988382 0.09 ENST00000356980.3
ENST00000379687.3
ENST00000379682.4
CXorf23
chromosome X open reading frame 23
chr8_-_99129338 0.09 ENST00000520507.1
HRSP12
heat-responsive protein 12
chr4_-_76944621 0.08 ENST00000306602.1
CXCL10
chemokine (C-X-C motif) ligand 10
chr6_-_39693111 0.08 ENST00000373215.3
ENST00000538893.1
ENST00000287152.7
ENST00000373216.3
KIF6
kinesin family member 6
chr19_-_51522955 0.08 ENST00000358789.3
KLK10
kallikrein-related peptidase 10
chr13_-_44735393 0.08 ENST00000400419.1
SMIM2
small integral membrane protein 2
chr4_-_25865159 0.08 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr17_+_79495397 0.08 ENST00000417245.2
ENST00000334850.7
FSCN2
fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus)
chr16_-_14109841 0.08 ENST00000576797.1
ENST00000575424.1
CTD-2135D7.5
CTD-2135D7.5
chr1_-_39347255 0.08 ENST00000454994.2
ENST00000357771.3
GJA9
gap junction protein, alpha 9, 59kDa
chr12_+_83080659 0.08 ENST00000321196.3
TMTC2
transmembrane and tetratricopeptide repeat containing 2
chr22_-_40929812 0.08 ENST00000422851.1
MKL1
megakaryoblastic leukemia (translocation) 1
chr14_+_88852059 0.08 ENST00000045347.7
SPATA7
spermatogenesis associated 7
chr12_-_10978957 0.07 ENST00000240619.2
TAS2R10
taste receptor, type 2, member 10
chr22_-_28490123 0.07 ENST00000442232.1
TTC28
tetratricopeptide repeat domain 28
chr13_+_78315348 0.07 ENST00000441784.1
SLAIN1
SLAIN motif family, member 1
chrX_+_134654540 0.07 ENST00000370752.4
DDX26B
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr8_+_52730143 0.07 ENST00000415643.1
AC090186.1
Uncharacterized protein
chrX_+_77166172 0.07 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATP7A
ATPase, Cu++ transporting, alpha polypeptide
chrX_+_123097014 0.07 ENST00000394478.1
STAG2
stromal antigen 2
chr14_+_65016620 0.07 ENST00000298705.1
PPP1R36
protein phosphatase 1, regulatory subunit 36
chr11_+_34664014 0.07 ENST00000527935.1
EHF
ets homologous factor
chr2_+_170440844 0.07 ENST00000260970.3
ENST00000433207.1
ENST00000409714.3
ENST00000462903.1
PPIG
peptidylprolyl isomerase G (cyclophilin G)
chr5_+_31193847 0.07 ENST00000514738.1
ENST00000265071.2
CDH6
cadherin 6, type 2, K-cadherin (fetal kidney)
chr4_-_74486109 0.07 ENST00000395777.2
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr15_-_55562451 0.07 ENST00000568803.1
RAB27A
RAB27A, member RAS oncogene family
chr7_-_5998714 0.07 ENST00000539903.1
RSPH10B
radial spoke head 10 homolog B (Chlamydomonas)
chr8_-_139926236 0.07 ENST00000303045.6
ENST00000435777.1
COL22A1
collagen, type XXII, alpha 1
chr2_+_105050794 0.07 ENST00000429464.1
ENST00000414442.1
ENST00000447380.1
AC013402.2
long intergenic non-protein coding RNA 1102
chrM_-_14670 0.06 ENST00000361681.2
MT-ND6
mitochondrially encoded NADH dehydrogenase 6
chr5_+_176811431 0.06 ENST00000512593.1
ENST00000324417.5
SLC34A1
solute carrier family 34 (type II sodium/phosphate contransporter), member 1
chr11_-_108093329 0.06 ENST00000278612.8
NPAT
nuclear protein, ataxia-telangiectasia locus
chr8_+_107738240 0.06 ENST00000449762.2
ENST00000297447.6
OXR1
oxidation resistance 1
chr7_-_78400598 0.06 ENST00000536571.1
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr13_+_78315295 0.06 ENST00000351546.3
SLAIN1
SLAIN motif family, member 1
chr11_+_35222629 0.06 ENST00000526553.1
CD44
CD44 molecule (Indian blood group)
chr7_-_37488547 0.06 ENST00000453399.1
ELMO1
engulfment and cell motility 1
chr1_-_242162375 0.06 ENST00000357246.3
MAP1LC3C
microtubule-associated protein 1 light chain 3 gamma
chr12_-_54653313 0.06 ENST00000550411.1
ENST00000439541.2
CBX5
chromobox homolog 5
chr8_-_99129384 0.06 ENST00000521560.1
ENST00000254878.3
HRSP12
heat-responsive protein 12
chr7_-_14029515 0.06 ENST00000430479.1
ENST00000405218.2
ENST00000343495.5
ETV1
ets variant 1
chr14_-_75083313 0.06 ENST00000556652.1
ENST00000555313.1
CTD-2207P18.2
CTD-2207P18.2
chr3_-_33686743 0.06 ENST00000333778.6
ENST00000539981.1
CLASP2
cytoplasmic linker associated protein 2
chr4_+_41614909 0.06 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIMCH1
LIM and calponin homology domains 1
chr19_+_1440838 0.06 ENST00000594262.1
AC027307.3
Uncharacterized protein
chr3_+_107364769 0.06 ENST00000449271.1
ENST00000425868.1
ENST00000449213.1
BBX
bobby sox homolog (Drosophila)
chr20_+_18447771 0.06 ENST00000377603.4
POLR3F
polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
chr15_+_80351977 0.06 ENST00000559157.1
ENST00000561012.1
ENST00000564367.1
ENST00000558494.1
ZFAND6
zinc finger, AN1-type domain 6
chr12_-_74686314 0.05 ENST00000551210.1
ENST00000515416.2
ENST00000549905.1
RP11-81H3.2
RP11-81H3.2
chr13_-_41593425 0.05 ENST00000239882.3
ELF1
E74-like factor 1 (ets domain transcription factor)
chr11_+_34663913 0.05 ENST00000532302.1
EHF
ets homologous factor
chr2_+_152214098 0.05 ENST00000243347.3
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr2_-_207023918 0.05 ENST00000455934.2
ENST00000449699.1
ENST00000454195.1
NDUFS1
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr2_-_207024233 0.05 ENST00000423725.1
ENST00000233190.6
NDUFS1
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
chr13_+_36050881 0.05 ENST00000537702.1
NBEA
neurobeachin
chr20_-_50722183 0.05 ENST00000371523.4
ZFP64
ZFP64 zinc finger protein
chr2_+_187454749 0.05 ENST00000261023.3
ENST00000374907.3
ITGAV
integrin, alpha V
chr2_+_149402989 0.05 ENST00000397424.2
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr12_-_118796971 0.05 ENST00000542902.1
TAOK3
TAO kinase 3
chr8_+_76452097 0.05 ENST00000396423.2
HNF4G
hepatocyte nuclear factor 4, gamma
chr8_-_42358742 0.05 ENST00000517366.1
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr3_+_16306837 0.05 ENST00000606098.1
OXNAD1
oxidoreductase NAD-binding domain containing 1
chr3_+_107364683 0.05 ENST00000413213.1
BBX
bobby sox homolog (Drosophila)
chr9_-_215744 0.05 ENST00000382387.2
C9orf66
chromosome 9 open reading frame 66
chr16_+_53412368 0.05 ENST00000565189.1
RP11-44F14.2
RP11-44F14.2
chr2_-_227050079 0.05 ENST00000423838.1
AC068138.1
AC068138.1
chr4_-_74486217 0.05 ENST00000335049.5
ENST00000307439.5
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr19_-_7697857 0.04 ENST00000598935.1
PCP2
Purkinje cell protein 2
chrX_+_591524 0.04 ENST00000554971.1
ENST00000381575.1
SHOX
short stature homeobox
chr14_-_38064198 0.04 ENST00000250448.2
FOXA1
forkhead box A1
chr1_-_227505289 0.04 ENST00000366765.3
CDC42BPA
CDC42 binding protein kinase alpha (DMPK-like)
chr19_+_30433372 0.04 ENST00000312051.6
URI1
URI1, prefoldin-like chaperone
chr8_-_40755333 0.04 ENST00000297737.6
ENST00000315769.7
ZMAT4
zinc finger, matrin-type 4
chr21_-_35284635 0.04 ENST00000429238.1
AP000304.12
AP000304.12
chr17_-_60142609 0.04 ENST00000397786.2
MED13
mediator complex subunit 13
chr7_-_14029283 0.04 ENST00000433547.1
ENST00000405192.2
ETV1
ets variant 1
chr14_+_21156915 0.04 ENST00000397990.4
ENST00000555597.1
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr15_-_54025300 0.04 ENST00000559418.1
WDR72
WD repeat domain 72
chr5_+_68860949 0.04 ENST00000507595.1
GTF2H2C
general transcription factor IIH, polypeptide 2C
chr10_-_115904361 0.04 ENST00000428953.1
ENST00000543782.1
C10orf118
chromosome 10 open reading frame 118
chr2_-_214017151 0.04 ENST00000452786.1
IKZF2
IKAROS family zinc finger 2 (Helios)
chr12_-_28123206 0.04 ENST00000542963.1
ENST00000535992.1
PTHLH
parathyroid hormone-like hormone
chr16_+_57279004 0.04 ENST00000219204.3
ARL2BP
ADP-ribosylation factor-like 2 binding protein
chr3_-_178984759 0.04 ENST00000349697.2
ENST00000497599.1
KCNMB3
potassium large conductance calcium-activated channel, subfamily M beta member 3
chr13_-_36788718 0.04 ENST00000317764.6
ENST00000379881.3
SOHLH2
spermatogenesis and oogenesis specific basic helix-loop-helix 2
chr2_+_179318295 0.04 ENST00000442710.1
DFNB59
deafness, autosomal recessive 59
chr12_-_52946923 0.04 ENST00000267119.5
KRT71
keratin 71
chr12_-_89746173 0.04 ENST00000308385.6
DUSP6
dual specificity phosphatase 6
chr14_+_104182061 0.04 ENST00000216602.6
ZFYVE21
zinc finger, FYVE domain containing 21
chr6_+_135502501 0.04 ENST00000527615.1
ENST00000420123.2
ENST00000525369.1
ENST00000528774.1
ENST00000534121.1
ENST00000534044.1
ENST00000533624.1
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr17_-_39211463 0.04 ENST00000542910.1
ENST00000398477.1
KRTAP2-2
keratin associated protein 2-2
chr3_-_114173530 0.04 ENST00000470311.1
ZBTB20
zinc finger and BTB domain containing 20
chr1_+_101003687 0.04 ENST00000315033.4
GPR88
G protein-coupled receptor 88
chr14_+_101359265 0.04 ENST00000599197.1
AL117190.3
Esophagus cancer-related gene-2 interaction susceptibility protein; Uncharacterized protein
chr3_+_130569429 0.04 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr8_+_107738343 0.04 ENST00000521592.1
OXR1
oxidation resistance 1
chr1_+_61548225 0.04 ENST00000371187.3
NFIA
nuclear factor I/A
chr4_+_175204865 0.04 ENST00000505124.1
CEP44
centrosomal protein 44kDa
chr5_+_61874562 0.04 ENST00000334994.5
ENST00000409534.1
LRRC70
IPO11
leucine rich repeat containing 70
importin 11
chr12_-_16760021 0.04 ENST00000540445.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr8_-_10512569 0.04 ENST00000382483.3
RP1L1
retinitis pigmentosa 1-like 1
chr1_+_160160346 0.04 ENST00000368078.3
CASQ1
calsequestrin 1 (fast-twitch, skeletal muscle)
chr3_-_100712292 0.04 ENST00000495063.1
ENST00000530539.1
ABI3BP
ABI family, member 3 (NESH) binding protein
chr5_+_67586465 0.03 ENST00000336483.5
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr21_+_35736302 0.03 ENST00000290310.3
KCNE2
potassium voltage-gated channel, Isk-related family, member 2
chr17_-_40337470 0.03 ENST00000293330.1
HCRT
hypocretin (orexin) neuropeptide precursor
chr17_+_39382900 0.03 ENST00000377721.3
ENST00000455970.2
KRTAP9-2
keratin associated protein 9-2
chr6_-_76072719 0.03 ENST00000370020.1
FILIP1
filamin A interacting protein 1
chr12_+_83080724 0.03 ENST00000548305.1
TMTC2
transmembrane and tetratricopeptide repeat containing 2
chr1_+_107683436 0.03 ENST00000370068.1
NTNG1
netrin G1
chr6_+_55192267 0.03 ENST00000340465.2
GFRAL
GDNF family receptor alpha like
chr19_-_51523412 0.03 ENST00000391805.1
ENST00000599077.1
KLK10
kallikrein-related peptidase 10
chr4_-_139163491 0.03 ENST00000280612.5
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr18_-_71959159 0.03 ENST00000494131.2
ENST00000397914.4
ENST00000340533.4
CYB5A
cytochrome b5 type A (microsomal)
chr3_-_27763803 0.03 ENST00000449599.1
EOMES
eomesodermin
chr4_+_95916947 0.03 ENST00000506363.1
BMPR1B
bone morphogenetic protein receptor, type IB
chr1_-_150738261 0.03 ENST00000448301.2
ENST00000368985.3
CTSS
cathepsin S
chr1_+_40713573 0.03 ENST00000372766.3
TMCO2
transmembrane and coiled-coil domains 2

Network of associatons between targets according to the STRING database.

First level regulatory network of LMX1B_MNX1_RAX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 0.3 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.1 0.2 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.0 0.1 GO:0006429 glutaminyl-tRNA aminoacylation(GO:0006425) leucyl-tRNA aminoacylation(GO:0006429)
0.0 0.2 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.2 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.0 0.3 GO:1901297 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.2 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.6 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.3 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 2.1 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.1 GO:1990637 response to prolactin(GO:1990637) regulation of ovarian follicle development(GO:2000354)
0.0 0.1 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.0 0.1 GO:0097187 dentinogenesis(GO:0097187) regulation of sodium-dependent phosphate transport(GO:2000118)
0.0 0.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.2 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.2 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0 0.0 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.0 0.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.1 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.2 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.1 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.0 GO:1990922 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.0 0.1 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.1 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.0 GO:0061743 motor learning(GO:0061743)
0.0 0.1 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.4 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.2 GO:0042693 muscle cell fate commitment(GO:0042693)
0.0 0.2 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0043614 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993) astrocyte end-foot(GO:0097450) glial limiting end-foot(GO:0097451)
0.1 0.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.2 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 1.8 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.3 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.4 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.1 GO:0034685 integrin alphav-beta6 complex(GO:0034685) integrin alphav-beta8 complex(GO:0034686)
0.0 0.2 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.1 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.2 GO:0005828 kinetochore microtubule(GO:0005828)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
0.0 0.1 GO:0004823 glutamine-tRNA ligase activity(GO:0004819) leucine-tRNA ligase activity(GO:0004823)
0.0 0.3 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.2 GO:0019770 IgG receptor activity(GO:0019770)
0.0 2.2 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.2 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.5 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.1 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532) copper-dependent protein binding(GO:0032767)
0.0 0.3 GO:0000150 recombinase activity(GO:0000150)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.3 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.4 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.8 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.1 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.1 GO:0034056 estrogen response element binding(GO:0034056)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway