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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for KLF15

Z-value: 0.87

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Transcription factors associated with KLF15

Gene Symbol Gene ID Gene Info
KLF15
ENSG00000163884.3 Kruppel like factor 15

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
KLF15hg19_v2_chr3_-_126076264_126076305-0.453.7e-01Click!

Activity profile of KLF15 motif

Sorted Z-values of KLF15 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_61602236 0.71 ENST00000514082.1
ENST00000407818.3
KIF2A
kinesin heavy chain member 2A
chr5_+_61601965 0.53 ENST00000401507.3
KIF2A
kinesin heavy chain member 2A
chr5_+_61602055 0.52 ENST00000381103.2
KIF2A
kinesin heavy chain member 2A
chr11_-_46142615 0.48 ENST00000529734.1
ENST00000323180.6
PHF21A
PHD finger protein 21A
chr14_+_32546145 0.44 ENST00000556611.1
ENST00000539826.2
ARHGAP5
Rho GTPase activating protein 5
chr1_+_203765437 0.42 ENST00000550078.1
ZBED6
zinc finger, BED-type containing 6
chr17_+_45771420 0.42 ENST00000578982.1
TBKBP1
TBK1 binding protein 1
chr19_-_11529225 0.38 ENST00000567431.1
RGL3
ral guanine nucleotide dissociation stimulator-like 3
chr19_+_55795493 0.35 ENST00000309383.1
BRSK1
BR serine/threonine kinase 1
chr12_+_19282643 0.34 ENST00000317589.4
ENST00000355397.3
ENST00000359180.3
ENST00000309364.4
ENST00000540972.1
ENST00000429027.2
PLEKHA5
pleckstrin homology domain containing, family A member 5
chr9_+_101867387 0.33 ENST00000374990.2
ENST00000552516.1
TGFBR1
transforming growth factor, beta receptor 1
chr3_-_185826718 0.31 ENST00000413301.1
ENST00000421809.1
ETV5
ets variant 5
chr8_+_109455830 0.31 ENST00000524143.1
EMC2
ER membrane protein complex subunit 2
chr14_+_32546274 0.31 ENST00000396582.2
ARHGAP5
Rho GTPase activating protein 5
chr11_-_77531752 0.31 ENST00000440064.2
ENST00000528095.1
RSF1
remodeling and spacing factor 1
chr10_+_35416223 0.30 ENST00000489321.1
ENST00000427847.2
ENST00000345491.3
ENST00000395895.2
ENST00000374728.3
ENST00000487132.1
CREM
cAMP responsive element modulator
chr21_-_27107198 0.30 ENST00000400094.1
ATP5J
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chr4_+_184426147 0.30 ENST00000302327.3
ING2
inhibitor of growth family, member 2
chr13_-_52026730 0.30 ENST00000420668.2
INTS6
integrator complex subunit 6
chr21_-_27107344 0.28 ENST00000457143.2
ATP5J
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chr2_+_48757278 0.28 ENST00000404752.1
ENST00000406226.1
STON1
stonin 1
chr9_-_6015607 0.27 ENST00000259569.5
RANBP6
RAN binding protein 6
chr1_-_93426998 0.27 ENST00000370310.4
FAM69A
family with sequence similarity 69, member A
chr21_-_27107283 0.27 ENST00000284971.3
ENST00000400099.1
ATP5J
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
chr3_-_113415441 0.27 ENST00000491165.1
ENST00000316407.4
KIAA2018
KIAA2018
chr14_+_32546485 0.26 ENST00000345122.3
ENST00000432921.1
ENST00000433497.1
ARHGAP5
Rho GTPase activating protein 5
chr8_+_109455845 0.26 ENST00000220853.3
EMC2
ER membrane protein complex subunit 2
chr2_+_46926326 0.26 ENST00000394861.2
SOCS5
suppressor of cytokine signaling 5
chr11_-_110167331 0.25 ENST00000534683.1
RDX
radixin
chr7_-_92157747 0.24 ENST00000428214.1
ENST00000438045.1
PEX1
peroxisomal biogenesis factor 1
chr2_-_9143786 0.24 ENST00000462696.1
ENST00000305997.3
MBOAT2
membrane bound O-acyltransferase domain containing 2
chr1_+_174128704 0.23 ENST00000457696.1
RABGAP1L
RAB GTPase activating protein 1-like
chr13_+_95364963 0.23 ENST00000438290.2
SOX21-AS1
SOX21 antisense RNA 1 (head to head)
chr1_+_174128536 0.23 ENST00000357444.6
ENST00000367689.3
RABGAP1L
RAB GTPase activating protein 1-like
chr21_+_27107672 0.23 ENST00000400075.3
GABPA
GA binding protein transcription factor, alpha subunit 60kDa
chr12_+_57522692 0.23 ENST00000554174.1
LRP1
low density lipoprotein receptor-related protein 1
chr19_-_1237990 0.23 ENST00000382477.2
ENST00000215376.6
ENST00000590083.1
C19orf26
chromosome 19 open reading frame 26
chr7_-_143991230 0.23 ENST00000543357.1
ARHGEF35
Rho guanine nucleotide exchange factor (GEF) 35
chr3_+_73045936 0.22 ENST00000356692.5
ENST00000488810.1
ENST00000394284.3
ENST00000295862.9
ENST00000495566.1
PPP4R2
protein phosphatase 4, regulatory subunit 2
chrX_+_53078465 0.22 ENST00000375466.2
GPR173
G protein-coupled receptor 173
chr16_+_2521500 0.22 ENST00000293973.1
NTN3
netrin 3
chr11_-_82782952 0.22 ENST00000534141.1
RAB30
RAB30, member RAS oncogene family
chr21_-_40685477 0.22 ENST00000342449.3
BRWD1
bromodomain and WD repeat domain containing 1
chr11_-_82782861 0.21 ENST00000524635.1
ENST00000526205.1
ENST00000527633.1
ENST00000533486.1
ENST00000533276.2
RAB30
RAB30, member RAS oncogene family
chr11_-_65641044 0.21 ENST00000527378.1
EFEMP2
EGF containing fibulin-like extracellular matrix protein 2
chr3_-_149688502 0.21 ENST00000481767.1
ENST00000475518.1
PFN2
profilin 2
chr5_+_139505520 0.21 ENST00000333305.3
IGIP
IgA-inducing protein
chr11_-_110167352 0.21 ENST00000533991.1
ENST00000528498.1
ENST00000405097.1
ENST00000528900.1
ENST00000530301.1
ENST00000343115.4
RDX
radixin
chr10_+_28822236 0.20 ENST00000347934.4
ENST00000354911.4
WAC
WW domain containing adaptor with coiled-coil
chr12_-_30907862 0.20 ENST00000541765.1
ENST00000537108.1
CAPRIN2
caprin family member 2
chr13_+_98628886 0.19 ENST00000490680.1
ENST00000539640.1
ENST00000403772.3
IPO5
importin 5
chr11_+_64058820 0.19 ENST00000422670.2
KCNK4
potassium channel, subfamily K, member 4
chr19_+_36706024 0.19 ENST00000443387.2
ZNF146
zinc finger protein 146
chr11_+_117015024 0.19 ENST00000530272.1
PAFAH1B2
platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
chr2_-_230786679 0.19 ENST00000543084.1
ENST00000343290.5
ENST00000389044.4
ENST00000283943.5
TRIP12
thyroid hormone receptor interactor 12
chr7_-_151107106 0.19 ENST00000334493.6
WDR86
WD repeat domain 86
chr10_+_127585118 0.19 ENST00000449042.2
FANK1
fibronectin type III and ankyrin repeat domains 1
chr5_-_141257954 0.19 ENST00000456271.1
ENST00000394536.3
ENST00000503492.1
ENST00000287008.3
PCDH1
protocadherin 1
chr9_+_101867359 0.19 ENST00000374994.4
TGFBR1
transforming growth factor, beta receptor 1
chr2_+_242254679 0.18 ENST00000428282.1
ENST00000360051.3
SEPT2
septin 2
chr6_-_18265050 0.18 ENST00000397239.3
DEK
DEK oncogene
chr16_+_23847339 0.18 ENST00000303531.7
PRKCB
protein kinase C, beta
chr10_-_15210615 0.18 ENST00000378150.1
NMT2
N-myristoyltransferase 2
chr6_+_149638876 0.18 ENST00000392282.1
TAB2
TGF-beta activated kinase 1/MAP3K7 binding protein 2
chr10_+_21823079 0.18 ENST00000377100.3
ENST00000377072.3
ENST00000446906.2
MLLT10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr7_-_92157760 0.18 ENST00000248633.4
PEX1
peroxisomal biogenesis factor 1
chr11_-_65640325 0.18 ENST00000307998.6
EFEMP2
EGF containing fibulin-like extracellular matrix protein 2
chr21_-_45681765 0.18 ENST00000431166.1
DNMT3L
DNA (cytosine-5-)-methyltransferase 3-like
chr17_-_46178527 0.18 ENST00000393408.3
CBX1
chromobox homolog 1
chr7_+_77166592 0.18 ENST00000248594.6
PTPN12
protein tyrosine phosphatase, non-receptor type 12
chr21_-_40685504 0.18 ENST00000380800.3
BRWD1
bromodomain and WD repeat domain containing 1
chr20_+_44650348 0.18 ENST00000454036.2
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr14_-_55738788 0.18 ENST00000556183.1
RP11-665C16.6
RP11-665C16.6
chr7_+_89841000 0.17 ENST00000287908.3
STEAP2
STEAP family member 2, metalloreductase
chr13_-_52027134 0.17 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
INTS6
integrator complex subunit 6
chr2_-_61697862 0.17 ENST00000398571.2
USP34
ubiquitin specific peptidase 34
chr11_-_46142948 0.17 ENST00000257821.4
PHF21A
PHD finger protein 21A
chr10_+_28822417 0.17 ENST00000428935.1
ENST00000420266.1
WAC
WW domain containing adaptor with coiled-coil
chr10_+_76871229 0.17 ENST00000372690.3
SAMD8
sterile alpha motif domain containing 8
chr2_-_165477971 0.17 ENST00000446413.2
GRB14
growth factor receptor-bound protein 14
chr9_-_14693417 0.17 ENST00000380916.4
ZDHHC21
zinc finger, DHHC-type containing 21
chr14_+_102228123 0.17 ENST00000422945.2
ENST00000554442.1
ENST00000556260.2
ENST00000328724.5
ENST00000557268.1
PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr13_-_49107205 0.17 ENST00000544904.1
ENST00000430805.2
ENST00000544492.1
RCBTB2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr14_+_58765103 0.16 ENST00000355431.3
ENST00000348476.3
ENST00000395168.3
ARID4A
AT rich interactive domain 4A (RBP1-like)
chr2_+_28974489 0.16 ENST00000455580.1
PPP1CB
protein phosphatase 1, catalytic subunit, beta isozyme
chr10_+_27793257 0.16 ENST00000375802.3
RAB18
RAB18, member RAS oncogene family
chr16_-_89008211 0.16 ENST00000569464.1
ENST00000569443.1
CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr7_-_94285402 0.16 ENST00000428696.2
ENST00000445866.2
SGCE
sarcoglycan, epsilon
chr9_+_131451480 0.16 ENST00000322030.8
SET
SET nuclear oncogene
chr7_-_143059780 0.16 ENST00000409578.1
ENST00000409346.1
FAM131B
family with sequence similarity 131, member B
chr6_-_80247140 0.16 ENST00000392959.1
ENST00000467898.3
LCA5
Leber congenital amaurosis 5
chr7_-_100493744 0.16 ENST00000428317.1
ENST00000441605.1
ACHE
acetylcholinesterase (Yt blood group)
chr10_+_76871353 0.16 ENST00000542569.1
SAMD8
sterile alpha motif domain containing 8
chr2_-_39347524 0.16 ENST00000395038.2
ENST00000402219.2
SOS1
son of sevenless homolog 1 (Drosophila)
chr6_-_18264706 0.16 ENST00000244776.7
ENST00000503715.1
DEK
DEK oncogene
chr1_+_97187318 0.16 ENST00000609116.1
ENST00000370198.1
ENST00000370197.1
ENST00000426398.2
ENST00000394184.3
PTBP2
polypyrimidine tract binding protein 2
chr17_-_73179046 0.16 ENST00000314523.7
ENST00000420826.2
SUMO2
small ubiquitin-like modifier 2
chr2_+_242254753 0.15 ENST00000428524.1
ENST00000445030.1
ENST00000407017.1
SEPT2
septin 2
chr22_+_29469100 0.15 ENST00000327813.5
ENST00000407188.1
KREMEN1
kringle containing transmembrane protein 1
chr4_+_39046615 0.15 ENST00000261425.3
ENST00000508137.2
KLHL5
kelch-like family member 5
chr1_-_110933611 0.15 ENST00000472422.2
ENST00000437429.2
SLC16A4
solute carrier family 16, member 4
chr2_+_173940668 0.15 ENST00000375213.3
MLTK
Mitogen-activated protein kinase kinase kinase MLT
chr17_-_73178599 0.15 ENST00000578238.1
SUMO2
small ubiquitin-like modifier 2
chr10_+_181418 0.15 ENST00000403354.1
ENST00000381607.4
ENST00000402736.1
ZMYND11
zinc finger, MYND-type containing 11
chr13_-_108867846 0.15 ENST00000442234.1
LIG4
ligase IV, DNA, ATP-dependent
chr3_-_88108192 0.15 ENST00000309534.6
CGGBP1
CGG triplet repeat binding protein 1
chr12_+_120933904 0.15 ENST00000550178.1
ENST00000550845.1
ENST00000549989.1
ENST00000552870.1
DYNLL1
dynein, light chain, LC8-type 1
chr14_-_67981870 0.15 ENST00000555994.1
TMEM229B
transmembrane protein 229B
chr19_-_47975106 0.15 ENST00000539381.1
ENST00000594353.1
ENST00000542837.1
SLC8A2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr1_+_33283246 0.14 ENST00000526230.1
ENST00000531256.1
ENST00000482212.1
S100PBP
S100P binding protein
chrX_-_153881842 0.14 ENST00000369585.3
ENST00000247306.4
CTAG2
cancer/testis antigen 2
chr10_+_27793197 0.14 ENST00000356940.6
ENST00000535776.1
RAB18
RAB18, member RAS oncogene family
chr5_+_131593364 0.14 ENST00000253754.3
ENST00000379018.3
PDLIM4
PDZ and LIM domain 4
chr12_+_120933859 0.14 ENST00000242577.6
ENST00000548214.1
ENST00000392508.2
DYNLL1
dynein, light chain, LC8-type 1
chr2_+_149402989 0.14 ENST00000397424.2
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr7_-_150675372 0.14 ENST00000262186.5
KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr2_-_32236002 0.14 ENST00000404530.1
MEMO1
mediator of cell motility 1
chr10_-_69991865 0.14 ENST00000373673.3
ATOH7
atonal homolog 7 (Drosophila)
chr7_-_94285472 0.14 ENST00000437425.2
ENST00000447873.1
ENST00000415788.2
SGCE
sarcoglycan, epsilon
chr6_-_18264406 0.14 ENST00000515742.1
DEK
DEK oncogene
chr6_+_44238203 0.13 ENST00000451188.2
TMEM151B
transmembrane protein 151B
chr4_+_74702214 0.13 ENST00000226317.5
ENST00000515050.1
CXCL6
chemokine (C-X-C motif) ligand 6
chr1_+_39547082 0.13 ENST00000602421.1
MACF1
microtubule-actin crosslinking factor 1
chrX_-_1572629 0.13 ENST00000534940.1
ASMTL
acetylserotonin O-methyltransferase-like
chr1_-_113498943 0.13 ENST00000369626.3
SLC16A1
solute carrier family 16 (monocarboxylate transporter), member 1
chr21_+_30671189 0.13 ENST00000286800.3
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr3_-_167452298 0.13 ENST00000475915.2
ENST00000462725.2
ENST00000461494.1
PDCD10
programmed cell death 10
chr7_-_92463210 0.13 ENST00000265734.4
CDK6
cyclin-dependent kinase 6
chr1_-_243418344 0.13 ENST00000366542.1
CEP170
centrosomal protein 170kDa
chr1_-_42800860 0.13 ENST00000445886.1
ENST00000361346.1
ENST00000361776.1
FOXJ3
forkhead box J3
chr6_+_12012170 0.13 ENST00000487103.1
HIVEP1
human immunodeficiency virus type I enhancer binding protein 1
chr17_-_4545170 0.13 ENST00000576394.1
ENST00000574640.1
ALOX15
arachidonate 15-lipoxygenase
chr1_-_110933663 0.13 ENST00000369781.4
ENST00000541986.1
ENST00000369779.4
SLC16A4
solute carrier family 16, member 4
chr11_-_77531858 0.13 ENST00000360355.2
RSF1
remodeling and spacing factor 1
chrX_+_119495934 0.13 ENST00000218008.3
ENST00000361319.3
ENST00000539306.1
ATP1B4
ATPase, Na+/K+ transporting, beta 4 polypeptide
chr17_-_27332931 0.13 ENST00000442608.3
ENST00000335960.6
SEZ6
seizure related 6 homolog (mouse)
chr12_-_123849374 0.13 ENST00000602398.1
ENST00000602750.1
SBNO1
strawberry notch homolog 1 (Drosophila)
chr2_+_242254507 0.13 ENST00000391973.2
SEPT2
septin 2
chr10_+_21823243 0.13 ENST00000307729.7
ENST00000377091.2
MLLT10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr16_+_23847355 0.13 ENST00000498058.1
PRKCB
protein kinase C, beta
chr2_-_176866978 0.13 ENST00000392540.2
ENST00000409660.1
ENST00000544803.1
ENST00000272748.4
KIAA1715
KIAA1715
chr19_-_55866104 0.13 ENST00000326529.4
COX6B2
cytochrome c oxidase subunit VIb polypeptide 2 (testis)
chr7_-_28220354 0.13 ENST00000283928.5
JAZF1
JAZF zinc finger 1
chr2_+_201170999 0.12 ENST00000439395.1
ENST00000444012.1
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr2_+_242255275 0.12 ENST00000391971.2
SEPT2
septin 2
chr10_-_112064665 0.12 ENST00000369603.5
SMNDC1
survival motor neuron domain containing 1
chr14_+_58765305 0.12 ENST00000445108.1
ARID4A
AT rich interactive domain 4A (RBP1-like)
chr17_-_27333163 0.12 ENST00000360295.9
SEZ6
seizure related 6 homolog (mouse)
chr4_-_39640513 0.12 ENST00000511809.1
ENST00000505729.1
SMIM14
small integral membrane protein 14
chr10_+_76871454 0.12 ENST00000372687.4
SAMD8
sterile alpha motif domain containing 8
chr11_-_62457371 0.12 ENST00000317449.4
LRRN4CL
LRRN4 C-terminal like
chr20_-_45280091 0.12 ENST00000396360.1
ENST00000435032.1
ENST00000413164.2
ENST00000372121.1
ENST00000339636.3
SLC13A3
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
chr7_-_105029329 0.12 ENST00000393651.3
ENST00000460391.1
SRPK2
SRSF protein kinase 2
chr9_+_130911723 0.12 ENST00000277480.2
ENST00000373013.2
ENST00000540948.1
LCN2
lipocalin 2
chr2_-_220173685 0.12 ENST00000423636.2
ENST00000442029.1
ENST00000412847.1
PTPRN
protein tyrosine phosphatase, receptor type, N
chr6_-_80247105 0.12 ENST00000369846.4
LCA5
Leber congenital amaurosis 5
chr3_-_156272924 0.12 ENST00000467789.1
ENST00000265044.2
SSR3
signal sequence receptor, gamma (translocon-associated protein gamma)
chr15_-_43910438 0.12 ENST00000432436.1
STRC
stereocilin
chr18_+_19321281 0.12 ENST00000261537.6
MIB1
mindbomb E3 ubiquitin protein ligase 1
chr17_-_42276574 0.12 ENST00000589805.1
ATXN7L3
ataxin 7-like 3
chr3_+_88108381 0.12 ENST00000473136.1
RP11-159G9.5
Uncharacterized protein
chr19_-_42636543 0.12 ENST00000528894.4
ENST00000560804.2
ENST00000560558.1
ENST00000560398.1
ENST00000526816.2
POU2F2
POU class 2 homeobox 2
chr4_+_74735102 0.12 ENST00000395761.3
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr14_+_59655369 0.12 ENST00000360909.3
ENST00000351081.1
ENST00000556135.1
DAAM1
dishevelled associated activator of morphogenesis 1
chr9_+_140772226 0.12 ENST00000277551.2
ENST00000371372.1
ENST00000277549.5
ENST00000371363.1
ENST00000371357.1
ENST00000371355.4
CACNA1B
calcium channel, voltage-dependent, N type, alpha 1B subunit
chrX_-_65859096 0.12 ENST00000456230.2
EDA2R
ectodysplasin A2 receptor
chr14_-_67982146 0.11 ENST00000557779.1
ENST00000557006.1
TMEM229B
transmembrane protein 229B
chr2_-_165697717 0.11 ENST00000439313.1
COBLL1
cordon-bleu WH2 repeat protein-like 1
chr19_-_49362621 0.11 ENST00000594195.1
ENST00000595867.1
PLEKHA4
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4
chr1_+_61548225 0.11 ENST00000371187.3
NFIA
nuclear factor I/A
chr7_+_89841024 0.11 ENST00000394626.1
STEAP2
STEAP family member 2, metalloreductase
chr8_-_494824 0.11 ENST00000427263.2
ENST00000324079.6
TDRP
testis development related protein
chr6_-_143832820 0.11 ENST00000002165.6
FUCA2
fucosidase, alpha-L- 2, plasma
chr11_-_102323740 0.11 ENST00000398136.2
TMEM123
transmembrane protein 123
chr17_+_65821780 0.11 ENST00000321892.4
ENST00000335221.5
ENST00000306378.6
BPTF
bromodomain PHD finger transcription factor
chr4_+_39640754 0.11 ENST00000529094.1
ENST00000533736.1
RP11-539G18.2
RP11-539G18.2
chr3_-_167452262 0.11 ENST00000487947.2
PDCD10
programmed cell death 10
chr22_-_50970506 0.11 ENST00000428989.2
ENST00000403326.1
ODF3B
outer dense fiber of sperm tails 3B
chr6_-_79787902 0.11 ENST00000275034.4
PHIP
pleckstrin homology domain interacting protein
chr4_+_56719782 0.11 ENST00000381295.2
ENST00000346134.7
ENST00000349598.6
EXOC1
exocyst complex component 1
chr15_+_45003675 0.11 ENST00000558401.1
ENST00000559916.1
ENST00000544417.1
B2M
beta-2-microglobulin
chr9_-_20621834 0.11 ENST00000429426.2
MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr17_-_73043046 0.11 ENST00000301587.4
ENST00000344546.4
ATP5H
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d
chr4_-_114682719 0.11 ENST00000394522.3
CAMK2D
calcium/calmodulin-dependent protein kinase II delta
chr19_-_11689752 0.11 ENST00000592659.1
ENST00000592828.1
ENST00000218758.5
ENST00000412435.2
ACP5
acid phosphatase 5, tartrate resistant
chr10_+_112631547 0.11 ENST00000280154.7
ENST00000393104.2
PDCD4
programmed cell death 4 (neoplastic transformation inhibitor)
chr2_+_139259324 0.11 ENST00000280098.4
SPOPL
speckle-type POZ protein-like
chr2_-_172017393 0.10 ENST00000442919.2
TLK1
tousled-like kinase 1
chr12_+_12966250 0.10 ENST00000352940.4
ENST00000358007.3
ENST00000544400.1
DDX47
DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
chr11_-_31839422 0.10 ENST00000423822.2
PAX6
paired box 6
chr15_-_27018175 0.10 ENST00000311550.5
GABRB3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr22_+_42470289 0.10 ENST00000419475.1
FAM109B
family with sequence similarity 109, member B
chr18_-_57364588 0.10 ENST00000439986.4
CCBE1
collagen and calcium binding EGF domains 1
chr12_-_54982300 0.10 ENST00000547431.1
PPP1R1A
protein phosphatase 1, regulatory (inhibitor) subunit 1A
chr1_+_33283043 0.10 ENST00000373476.1
ENST00000373475.5
ENST00000529027.1
ENST00000398243.3
S100PBP
S100P binding protein
chr17_-_60142609 0.10 ENST00000397786.2
MED13
mediator complex subunit 13
chr2_+_242255297 0.10 ENST00000401990.1
ENST00000407971.1
ENST00000436795.1
ENST00000411484.1
ENST00000434955.1
ENST00000402092.2
ENST00000441533.1
ENST00000443492.1
ENST00000437066.1
ENST00000429791.1
SEPT2
septin 2
chr21_-_40685536 0.10 ENST00000341322.4
BRWD1
bromodomain and WD repeat domain containing 1
chr1_-_243418621 0.10 ENST00000366544.1
ENST00000366543.1
CEP170
centrosomal protein 170kDa
chr8_-_68255912 0.10 ENST00000262215.3
ENST00000519436.1
ARFGEF1
ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF15

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0060151 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.1 0.5 GO:1905075 occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.1 0.4 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.1 0.4 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.1 0.3 GO:0050976 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976)
0.1 0.6 GO:0098728 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1 0.2 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.1 0.1 GO:0003032 detection of oxygen(GO:0003032)
0.1 0.3 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.1 0.2 GO:0018008 N-terminal peptidyl-glycine N-myristoylation(GO:0018008)
0.1 0.4 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.1 0.2 GO:0040040 thermosensory behavior(GO:0040040)
0.1 0.2 GO:1904761 negative regulation of myofibroblast differentiation(GO:1904761)
0.1 0.2 GO:0021919 BMP signaling pathway involved in spinal cord dorsal/ventral patterning(GO:0021919)
0.1 0.2 GO:0051102 DNA ligation involved in DNA recombination(GO:0051102)
0.0 0.3 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.2 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.0 0.1 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.0 0.1 GO:0015728 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
0.0 0.4 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.4 GO:0033216 ferric iron import(GO:0033216)
0.0 0.1 GO:0035963 response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963)
0.0 0.2 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.0 0.2 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.0 0.3 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.1 GO:1990502 dense core granule maturation(GO:1990502)
0.0 0.4 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.2 GO:1904693 midbrain morphogenesis(GO:1904693)
0.0 1.1 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.1 GO:0019085 early viral transcription(GO:0019085)
0.0 0.2 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.3 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.2 GO:0002225 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.0 0.2 GO:0071422 tricarboxylic acid transport(GO:0006842) succinate transport(GO:0015744) citrate transport(GO:0015746) succinate transmembrane transport(GO:0071422)
0.0 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.1 GO:0035668 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.0 0.5 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.5 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0 0.2 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.6 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.1 GO:0090222 centrosome-templated microtubule nucleation(GO:0090222)
0.0 0.4 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.1 GO:0006597 spermine biosynthetic process(GO:0006597)
0.0 0.3 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.2 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 0.1 GO:0050894 determination of affect(GO:0050894)
0.0 0.2 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.1 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.0 0.1 GO:1904501 glial cell fate determination(GO:0007403) negative regulation of mitotic cell cycle, embryonic(GO:0045976) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.0 0.1 GO:0002778 antimicrobial peptide production(GO:0002775) antibacterial peptide production(GO:0002778)
0.0 0.2 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.2 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.0 0.1 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.0 0.1 GO:1901490 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748) regulation of lymphangiogenesis(GO:1901490)
0.0 0.1 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.0 0.1 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 1.8 GO:0090307 mitotic spindle assembly(GO:0090307)
0.0 0.1 GO:0034436 glycoprotein transport(GO:0034436)
0.0 0.2 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.1 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.0 0.1 GO:0072240 ascending thin limb development(GO:0072021) DCT cell differentiation(GO:0072069) metanephric ascending thin limb development(GO:0072218) metanephric DCT cell differentiation(GO:0072240)
0.0 0.0 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.1 GO:0010459 negative regulation of heart rate(GO:0010459)
0.0 0.1 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.0 0.1 GO:0001923 B-1 B cell differentiation(GO:0001923)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.1 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.4 GO:0016180 snRNA processing(GO:0016180)
0.0 0.2 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.0 0.4 GO:0060074 synapse maturation(GO:0060074)
0.0 0.3 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.0 GO:0036216 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.0 0.2 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 0.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.2 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.0 0.2 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.1 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.0 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.0 0.2 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.0 0.0 GO:0003192 mitral valve formation(GO:0003192)
0.0 0.3 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.0 GO:0061083 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0031213 RSF complex(GO:0031213)
0.1 1.1 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 0.1 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.1 0.5 GO:0051286 cell tip(GO:0051286)
0.0 0.5 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.2 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.0 0.4 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 1.8 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.6 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.7 GO:0097227 sperm annulus(GO:0097227)
0.0 0.4 GO:0042587 glycogen granule(GO:0042587)
0.0 0.5 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.2 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.2 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.3 GO:0001939 female pronucleus(GO:0001939)
0.0 0.2 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.0 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.1 GO:0032449 CBM complex(GO:0032449)
0.0 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.2 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.1 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.7 GO:1990391 DNA repair complex(GO:1990391)
0.0 0.0 GO:0048179 activin receptor complex(GO:0048179)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.1 0.4 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.1 0.3 GO:0098782 mechanically-gated potassium channel activity(GO:0098782)
0.1 0.4 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.1 0.2 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.1 0.2 GO:0019107 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.1 0.4 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.2 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.5 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
0.0 0.4 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.3 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.1 GO:0047977 hepoxilin-epoxide hydrolase activity(GO:0047977)
0.0 0.2 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 0.1 GO:0016768 spermine synthase activity(GO:0016768)
0.0 0.1 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.0 0.2 GO:0017153 citrate transmembrane transporter activity(GO:0015137) succinate transmembrane transporter activity(GO:0015141) tricarboxylic acid transmembrane transporter activity(GO:0015142) sodium:dicarboxylate symporter activity(GO:0017153)
0.0 0.2 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.2 GO:0034711 inhibin binding(GO:0034711)
0.0 0.1 GO:0050436 microfibril binding(GO:0050436)
0.0 0.3 GO:0031386 protein tag(GO:0031386)
0.0 0.3 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.1 GO:0031877 somatostatin receptor binding(GO:0031877)
0.0 0.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.0 0.1 GO:0035276 ethanol binding(GO:0035276)
0.0 0.1 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.1 GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 0.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.3 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.2 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.1 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0 0.2 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 1.0 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.2 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 1.9 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.0 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.0 0.1 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.1 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.0 0.1 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.2 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 0.1 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.0 0.0 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.4 GO:0000993 RNA polymerase II core binding(GO:0000993)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.3 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.4 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.5 PID ALK1 PATHWAY ALK1 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 1.8 REACTOME KINESINS Genes involved in Kinesins
0.0 0.2 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.4 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.6 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.4 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.4 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors