Project
A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)
Navigation
Downloads
Results for IRX5
Z-value: 1.02
Motif logo
Transcription factors associated with IRX5
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| IRX5 | hg19_v2_chr16_+_54964740_54964789 | -0.27 | 6.0e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of IRX5
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.6 | GO:0061635 | regulation of protein complex stability(GO:0061635) |
| 0.0 | 0.7 | GO:0006825 | copper ion transport(GO:0006825) |
| 0.1 | 0.6 | GO:0007079 | mitotic chromosome movement towards spindle pole(GO:0007079) |
| 0.1 | 0.6 | GO:0045919 | positive regulation of cytolysis(GO:0045919) |
| 0.2 | 0.5 | GO:0071262 | regulation of eIF2 alpha phosphorylation by amino acid starvation(GO:0060733) regulation of translational initiation in response to starvation(GO:0071262) positive regulation of translational initiation in response to starvation(GO:0071264) |
| 0.1 | 0.5 | GO:0002740 | negative regulation of cytokine secretion involved in immune response(GO:0002740) Tie signaling pathway(GO:0048014) |
| 0.0 | 0.5 | GO:0034058 | endosomal vesicle fusion(GO:0034058) |
| 0.1 | 0.4 | GO:1990926 | short-term synaptic potentiation(GO:1990926) |
| 0.1 | 0.3 | GO:0009786 | regulation of asymmetric cell division(GO:0009786) |
| 0.1 | 0.3 | GO:0032053 | ciliary basal body organization(GO:0032053) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.9 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
| 0.0 | 0.9 | GO:0005844 | polysome(GO:0005844) |
| 0.1 | 0.7 | GO:0033588 | Elongator holoenzyme complex(GO:0033588) |
| 0.0 | 0.7 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.0 | 0.4 | GO:0070032 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) |
| 0.0 | 0.3 | GO:0072687 | meiotic spindle(GO:0072687) |
| 0.0 | 0.3 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
| 0.0 | 0.3 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
| 0.0 | 0.3 | GO:0031462 | Cul2-RING ubiquitin ligase complex(GO:0031462) |
| 0.0 | 0.3 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.9 | GO:0043515 | kinetochore binding(GO:0043515) |
| 0.2 | 0.7 | GO:0032767 | copper-dependent protein binding(GO:0032767) |
| 0.0 | 0.5 | GO:0008607 | phosphorylase kinase regulator activity(GO:0008607) |
| 0.0 | 0.4 | GO:0033592 | RNA strand annealing activity(GO:0033592) |
| 0.0 | 0.4 | GO:0004745 | retinol dehydrogenase activity(GO:0004745) |
| 0.1 | 0.3 | GO:0004822 | isoleucine-tRNA ligase activity(GO:0004822) |
| 0.0 | 0.3 | GO:0004359 | glutaminase activity(GO:0004359) |
| 0.0 | 0.3 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
| 0.0 | 0.3 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
| 0.0 | 0.3 | GO:0086007 | voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | PID CONE PATHWAY | Visual signal transduction: Cones |
| 0.0 | 0.1 | ST INTERFERON GAMMA PATHWAY | Interferon gamma pathway. |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.6 | REACTOME TIE2 SIGNALING | Genes involved in Tie2 Signaling |
| 0.0 | 0.4 | REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Acetylcholine Neurotransmitter Release Cycle |
| 0.0 | 0.3 | REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |