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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for IRF9

Z-value: 7.23

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Transcription factors associated with IRF9

Gene Symbol Gene ID Gene Info
IRF9
ENSG00000213928.4 interferon regulatory factor 9

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IRF9hg19_v2_chr14_+_24630465_246305311.006.3e-06Click!

Activity profile of IRF9 motif

Sorted Z-values of IRF9 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr21_+_42798094 59.76 ENST00000398598.3
ENST00000455164.2
ENST00000424365.1
MX1
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)
chr1_+_948803 50.09 ENST00000379389.4
ISG15
ISG15 ubiquitin-like modifier
chr21_+_42798158 39.88 ENST00000441677.1
MX1
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)
chr21_+_42798124 38.95 ENST00000417963.1
MX1
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)
chr21_+_42797958 33.18 ENST00000419044.1
MX1
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)
chr11_-_615570 27.91 ENST00000525445.1
ENST00000348655.6
ENST00000397566.1
IRF7
interferon regulatory factor 7
chr11_-_615942 26.71 ENST00000397562.3
ENST00000330243.5
ENST00000397570.1
ENST00000397574.2
IRF7
interferon regulatory factor 7
chr9_-_32526184 20.02 ENST00000545044.1
ENST00000379868.1
DDX58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr14_+_24630465 19.86 ENST00000557894.1
ENST00000559284.1
ENST00000560275.1
IRF9
interferon regulatory factor 9
chr14_+_94577074 19.41 ENST00000444961.1
ENST00000448882.1
ENST00000557098.1
ENST00000554800.1
ENST00000556544.1
ENST00000298902.5
ENST00000555819.1
ENST00000557634.1
ENST00000555744.1
IFI27
interferon, alpha-inducible protein 27
chr3_-_122283079 17.65 ENST00000471785.1
ENST00000466126.1
PARP9
poly (ADP-ribose) polymerase family, member 9
chr1_+_79115503 17.29 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
IFI44
interferon-induced protein 44
chr3_-_122283100 17.06 ENST00000492382.1
ENST00000462315.1
PARP9
poly (ADP-ribose) polymerase family, member 9
chr3_-_122283424 16.48 ENST00000477522.2
ENST00000360356.2
PARP9
poly (ADP-ribose) polymerase family, member 9
chr12_-_121477039 16.45 ENST00000257570.5
OASL
2'-5'-oligoadenylate synthetase-like
chr12_-_121476959 16.25 ENST00000339275.5
OASL
2'-5'-oligoadenylate synthetase-like
chr4_-_169239921 15.25 ENST00000514995.1
ENST00000393743.3
DDX60
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr12_+_113344755 14.71 ENST00000550883.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr12_+_113344582 14.24 ENST00000202917.5
ENST00000445409.2
ENST00000452357.2
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr12_+_113344811 13.41 ENST00000551241.1
ENST00000553185.1
ENST00000550689.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr19_-_17516449 12.93 ENST00000252593.6
BST2
bone marrow stromal cell antigen 2
chr10_+_91092241 11.90 ENST00000371811.4
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr2_-_163175133 11.85 ENST00000421365.2
ENST00000263642.2
IFIH1
interferon induced with helicase C domain 1
chr9_-_32526299 11.15 ENST00000379882.1
ENST00000379883.2
DDX58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr2_-_7005785 11.05 ENST00000256722.5
ENST00000404168.1
ENST00000458098.1
CMPK2
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr3_+_122283175 10.14 ENST00000383661.3
DTX3L
deltex 3-like (Drosophila)
chr3_+_122283064 9.85 ENST00000296161.4
DTX3L
deltex 3-like (Drosophila)
chr12_+_113376157 9.72 ENST00000228928.7
OAS3
2'-5'-oligoadenylate synthetase 3, 100kDa
chr12_+_113376249 9.41 ENST00000551007.1
ENST00000548514.1
OAS3
2'-5'-oligoadenylate synthetase 3, 100kDa
chr3_-_146262365 8.27 ENST00000448787.2
PLSCR1
phospholipid scramblase 1
chr2_-_37384175 7.67 ENST00000411537.2
ENST00000233057.4
ENST00000395127.2
ENST00000390013.3
EIF2AK2
eukaryotic translation initiation factor 2-alpha kinase 2
chr3_-_146262352 6.59 ENST00000462666.1
PLSCR1
phospholipid scramblase 1
chr11_+_5646213 6.49 ENST00000429814.2
TRIM34
tripartite motif containing 34
chr1_+_79086088 6.27 ENST00000370751.5
ENST00000342282.3
IFI44L
interferon-induced protein 44-like
chr3_-_146262428 6.09 ENST00000486631.1
PLSCR1
phospholipid scramblase 1
chr3_-_146262293 5.68 ENST00000448205.1
PLSCR1
phospholipid scramblase 1
chr4_+_89378261 5.30 ENST00000264350.3
HERC5
HECT and RLD domain containing E3 ubiquitin protein ligase 5
chr3_-_146262488 5.29 ENST00000487389.1
PLSCR1
phospholipid scramblase 1
chr3_-_146262637 4.89 ENST00000472349.1
ENST00000342435.4
PLSCR1
phospholipid scramblase 1
chr4_-_169401628 4.85 ENST00000514748.1
ENST00000512371.1
ENST00000260184.7
ENST00000505890.1
ENST00000511577.1
DDX60L
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like
chr19_+_10196981 4.63 ENST00000591813.1
C19orf66
chromosome 19 open reading frame 66
chr10_+_91174486 4.33 ENST00000416601.1
IFIT5
interferon-induced protein with tetratricopeptide repeats 5
chr4_-_76944621 4.30 ENST00000306602.1
CXCL10
chemokine (C-X-C motif) ligand 10
chr10_+_91061712 4.08 ENST00000371826.3
IFIT2
interferon-induced protein with tetratricopeptide repeats 2
chr10_+_91174314 4.03 ENST00000371795.4
IFIT5
interferon-induced protein with tetratricopeptide repeats 5
chr17_-_54991395 4.00 ENST00000316881.4
TRIM25
tripartite motif containing 25
chr17_-_54991369 3.97 ENST00000537230.1
TRIM25
tripartite motif containing 25
chr3_+_122399444 3.95 ENST00000474629.2
PARP14
poly (ADP-ribose) polymerase family, member 14
chr13_+_50070491 3.87 ENST00000496612.1
ENST00000357596.3
ENST00000485919.1
ENST00000442195.1
PHF11
PHD finger protein 11
chr22_+_18632666 3.81 ENST00000215794.7
USP18
ubiquitin specific peptidase 18
chr13_+_50070077 3.72 ENST00000378319.3
ENST00000426879.1
PHF11
PHD finger protein 11
chr2_-_55920952 3.65 ENST00000447944.2
PNPT1
polyribonucleotide nucleotidyltransferase 1
chr1_+_158979680 3.65 ENST00000368131.4
ENST00000340979.6
IFI16
interferon, gamma-inducible protein 16
chr12_-_56753858 3.56 ENST00000314128.4
ENST00000557235.1
ENST00000418572.2
STAT2
signal transducer and activator of transcription 2, 113kDa
chr11_-_57335280 3.15 ENST00000287156.4
UBE2L6
ubiquitin-conjugating enzyme E2L 6
chr5_-_95297534 3.06 ENST00000513343.1
ENST00000431061.2
ELL2
elongation factor, RNA polymerase II, 2
chr1_+_158979686 2.90 ENST00000368132.3
ENST00000295809.7
IFI16
interferon, gamma-inducible protein 16
chr3_+_159706537 2.89 ENST00000305579.2
ENST00000480787.1
ENST00000466512.1
IL12A
interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
chr11_-_57334732 2.87 ENST00000526659.1
ENST00000527022.1
UBE2L6
ubiquitin-conjugating enzyme E2L 6
chr1_-_154580616 2.76 ENST00000368474.4
ADAR
adenosine deaminase, RNA-specific
chr1_+_158979792 2.76 ENST00000359709.3
ENST00000430894.2
IFI16
interferon, gamma-inducible protein 16
chr6_-_31324943 2.52 ENST00000412585.2
ENST00000434333.1
HLA-B
major histocompatibility complex, class I, B
chr1_-_150738261 2.33 ENST00000448301.2
ENST00000368985.3
CTSS
cathepsin S
chr1_+_66820058 2.13 ENST00000480109.2
PDE4B
phosphodiesterase 4B, cAMP-specific
chr12_-_121476750 2.06 ENST00000543677.1
OASL
2'-5'-oligoadenylate synthetase-like
chr4_-_147442817 1.90 ENST00000507030.1
SLC10A7
solute carrier family 10, member 7
chr9_+_102668915 1.83 ENST00000259400.6
ENST00000531035.1
ENST00000525640.1
ENST00000534052.1
ENST00000526607.1
STX17
syntaxin 17
chr15_+_74287035 1.78 ENST00000395132.2
ENST00000268059.6
ENST00000354026.6
ENST00000268058.3
ENST00000565898.1
ENST00000569477.1
ENST00000569965.1
ENST00000567543.1
ENST00000436891.3
ENST00000435786.2
ENST00000564428.1
ENST00000359928.4
PML
promyelocytic leukemia
chr6_+_126240442 1.66 ENST00000448104.1
ENST00000438495.1
ENST00000444128.1
NCOA7
nuclear receptor coactivator 7
chr3_+_122399697 1.62 ENST00000494811.1
PARP14
poly (ADP-ribose) polymerase family, member 14
chr9_-_107754034 1.58 ENST00000457720.1
RP11-217B7.3
RP11-217B7.3
chr17_+_6659153 1.47 ENST00000441631.1
ENST00000438512.1
ENST00000346752.4
ENST00000361842.3
XAF1
XIAP associated factor 1
chr11_-_4414880 1.28 ENST00000254436.7
ENST00000543625.1
TRIM21
tripartite motif containing 21
chr15_+_45003675 1.27 ENST00000558401.1
ENST00000559916.1
ENST00000544417.1
B2M
beta-2-microglobulin
chr2_-_152146385 1.22 ENST00000414946.1
ENST00000243346.5
NMI
N-myc (and STAT) interactor
chr3_-_130745403 1.16 ENST00000504725.1
ENST00000509060.1
ASTE1
asteroid homolog 1 (Drosophila)
chr3_-_142166796 1.16 ENST00000392981.2
XRN1
5'-3' exoribonuclease 1
chr10_-_25241499 1.09 ENST00000376378.1
ENST00000376376.3
ENST00000320152.6
PRTFDC1
phosphoribosyl transferase domain containing 1
chr9_+_33264861 1.00 ENST00000223500.8
CHMP5
charged multivesicular body protein 5
chr5_-_95297678 0.92 ENST00000237853.4
ELL2
elongation factor, RNA polymerase II, 2
chr3_-_28390120 0.78 ENST00000334100.6
AZI2
5-azacytidine induced 2
chr9_+_33265011 0.62 ENST00000419016.2
CHMP5
charged multivesicular body protein 5
chr9_+_74764340 0.55 ENST00000376986.1
ENST00000358399.3
GDA
guanine deaminase
chr5_-_137911049 0.54 ENST00000297185.3
HSPA9
heat shock 70kDa protein 9 (mortalin)
chr6_-_82462425 0.53 ENST00000369754.3
ENST00000320172.6
ENST00000369756.3
FAM46A
family with sequence similarity 46, member A
chr4_-_147442982 0.50 ENST00000511374.1
ENST00000264986.3
SLC10A7
solute carrier family 10, member 7
chr6_-_32806506 0.46 ENST00000374897.2
ENST00000452392.2
TAP2
TAP2
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
Uncharacterized protein
chr3_-_142166904 0.45 ENST00000264951.4
XRN1
5'-3' exoribonuclease 1
chr17_-_40264692 0.44 ENST00000591220.1
ENST00000251642.3
DHX58
DEXH (Asp-Glu-X-His) box polypeptide 58
chr5_-_142783365 0.43 ENST00000508760.1
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr6_-_8102714 0.42 ENST00000502429.1
ENST00000429723.2
ENST00000507463.1
ENST00000379715.5
EEF1E1
eukaryotic translation elongation factor 1 epsilon 1
chr2_-_152118352 0.34 ENST00000331426.5
RBM43
RNA binding motif protein 43
chr6_-_32806483 0.29 ENST00000374899.4
TAP2
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
chr7_-_84121858 0.29 ENST00000448879.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr2_+_33701707 0.28 ENST00000425210.1
ENST00000444784.1
ENST00000423159.1
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr3_-_141747459 0.23 ENST00000477292.1
ENST00000478006.1
ENST00000495310.1
ENST00000486111.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr2_-_166702601 0.23 ENST00000428888.1
AC009495.4
AC009495.4
chr10_+_115439699 0.17 ENST00000369315.1
CASP7
caspase 7, apoptosis-related cysteine peptidase
chr6_-_105584560 0.07 ENST00000336775.5
BVES
blood vessel epicardial substance
chr10_+_115439282 0.07 ENST00000369321.2
ENST00000345633.4
CASP7
caspase 7, apoptosis-related cysteine peptidase

Network of associatons between targets according to the STRING database.

First level regulatory network of IRF9

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
18.2 54.6 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
10.5 41.9 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
8.0 167.8 GO:0003374 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
5.1 61.4 GO:0032020 ISG15-protein conjugation(GO:0032020)
4.7 51.2 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
4.3 12.9 GO:1901253 negative regulation of dendritic cell cytokine production(GO:0002731) negative regulation of intracellular transport of viral material(GO:1901253)
3.7 36.8 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659) regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
2.8 11.0 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
2.6 15.7 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
1.6 19.1 GO:0060700 regulation of ribonuclease activity(GO:0060700)
1.2 16.0 GO:0035457 cellular response to interferon-alpha(GO:0035457)
1.2 3.7 GO:2000625 rRNA import into mitochondrion(GO:0035928) regulation of miRNA catabolic process(GO:2000625) positive regulation of miRNA catabolic process(GO:2000627)
1.0 90.3 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.7 4.3 GO:0010819 regulation of T cell chemotaxis(GO:0010819)
0.5 2.0 GO:0002428 antigen processing and presentation of peptide antigen via MHC class Ib(GO:0002428)
0.5 41.9 GO:0060337 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.5 10.0 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.4 1.8 GO:0016240 autophagosome docking(GO:0016240)
0.4 1.1 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.4 18.5 GO:0010390 histone monoubiquitination(GO:0010390)
0.4 2.9 GO:2000510 regulation of dendritic cell chemotaxis(GO:2000508) positive regulation of dendritic cell chemotaxis(GO:2000510)
0.2 1.2 GO:0045349 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.1 2.1 GO:1901078 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 1.6 GO:1904903 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.1 0.4 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.1 1.7 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 6.5 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.1 2.3 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.5 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.0 0.4 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.0 4.0 GO:0042795 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 14.5 GO:0009615 response to virus(GO:0009615)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.8 GO:0044530 supraspliceosomal complex(GO:0044530)
0.4 8.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.3 3.8 GO:0042612 MHC class I protein complex(GO:0042612)
0.3 2.3 GO:0036021 endolysosome lumen(GO:0036021)
0.3 190.6 GO:0031965 nuclear membrane(GO:0031965)
0.3 2.9 GO:0031906 late endosome lumen(GO:0031906)
0.3 3.7 GO:0042788 polysomal ribosome(GO:0042788)
0.2 12.9 GO:0005771 multivesicular body(GO:0005771)
0.2 1.8 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.1 31.2 GO:0032587 ruffle membrane(GO:0032587)
0.1 0.7 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 15.2 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.1 32.3 GO:0045121 membrane raft(GO:0045121)
0.1 2.1 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 4.0 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 32.3 GO:0010008 endosome membrane(GO:0010008)
0.0 212.5 GO:0005654 nucleoplasm(GO:0005654)
0.0 7.7 GO:0005840 ribosome(GO:0005840)
0.0 28.4 GO:0005739 mitochondrion(GO:0005739)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
8.0 96.3 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
3.6 46.9 GO:0031386 protein tag(GO:0031386)
2.8 11.0 GO:0009041 uridylate kinase activity(GO:0009041)
1.8 36.8 GO:0017128 phospholipid scramblase activity(GO:0017128)
1.7 50.1 GO:0070403 NAD+ binding(GO:0070403)
1.4 4.3 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
1.3 7.7 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
1.1 11.3 GO:0042296 ISG15 transferase activity(GO:0042296)
0.5 3.7 GO:0034046 poly(G) binding(GO:0034046)
0.5 19.4 GO:0005521 lamin binding(GO:0005521)
0.5 67.1 GO:0003727 single-stranded RNA binding(GO:0003727)
0.4 12.9 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.4 2.9 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.4 167.8 GO:0008017 microtubule binding(GO:0008017)
0.4 49.9 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.3 8.0 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.2 5.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 28.7 GO:0001047 core promoter binding(GO:0001047)
0.1 0.8 GO:0023029 MHC class Ib protein binding(GO:0023029)
0.1 2.1 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 20.0 GO:0042393 histone binding(GO:0042393)
0.1 2.3 GO:0043394 proteoglycan binding(GO:0043394)
0.1 0.4 GO:0002151 G-quadruplex RNA binding(GO:0002151) G-quadruplex DNA binding(GO:0051880)
0.0 0.7 GO:0032183 SUMO binding(GO:0032183)
0.0 1.1 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.0 1.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 3.8 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 4.8 GO:0004386 helicase activity(GO:0004386)
0.0 1.7 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 1.2 GO:0004518 nuclease activity(GO:0004518)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 23.4 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.3 54.2 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.2 7.6 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.1 19.4 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.1 7.7 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.1 2.9 PID IL27 PATHWAY IL27-mediated signaling events
0.1 5.5 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 4.3 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.7 PID MYC PATHWAY C-MYC pathway
0.0 1.3 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 1.7 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
5.0 105.6 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
4.1 371.5 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.9 3.6 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.2 11.3 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 4.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 7.7 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 19.1 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 0.8 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 1.6 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 2.1 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.4 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.7 REACTOME INTERFERON SIGNALING Genes involved in Interferon Signaling
0.0 0.4 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation