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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HOXC12_HOXD12

Z-value: 0.63

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Transcription factors associated with HOXC12_HOXD12

Gene Symbol Gene ID Gene Info
HOXC12
ENSG00000123407.3 homeobox C12
HOXD12
ENSG00000170178.5 homeobox D12

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXD12hg19_v2_chr2_+_176964458_1769645400.522.9e-01Click!
HOXC12hg19_v2_chr12_+_54348618_543486930.522.9e-01Click!

Activity profile of HOXC12_HOXD12 motif

Sorted Z-values of HOXC12_HOXD12 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_113354341 1.91 ENST00000553152.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr5_-_39270725 0.54 ENST00000512138.1
ENST00000512982.1
ENST00000540520.1
FYB
FYN binding protein
chr1_-_220219775 0.50 ENST00000609181.1
EPRS
glutamyl-prolyl-tRNA synthetase
chr1_+_219347203 0.46 ENST00000366927.3
LYPLAL1
lysophospholipase-like 1
chr11_-_7904464 0.40 ENST00000502624.2
ENST00000527565.1
RP11-35J10.5
RP11-35J10.5
chr19_-_23869999 0.36 ENST00000601935.1
ENST00000359788.4
ENST00000600313.1
ENST00000596211.1
ENST00000599168.1
ZNF675
zinc finger protein 675
chr13_+_53030107 0.35 ENST00000490903.1
ENST00000480747.1
CKAP2
cytoskeleton associated protein 2
chr1_-_220220000 0.34 ENST00000366923.3
EPRS
glutamyl-prolyl-tRNA synthetase
chr22_+_38035623 0.33 ENST00000336738.5
ENST00000442465.2
SH3BP1
SH3-domain binding protein 1
chr2_+_172778952 0.32 ENST00000392584.1
ENST00000264108.4
HAT1
histone acetyltransferase 1
chr1_+_156308403 0.32 ENST00000481479.1
ENST00000368252.1
ENST00000466306.1
ENST00000368251.1
TSACC
TSSK6 activating co-chaperone
chr18_-_812517 0.32 ENST00000584307.1
YES1
v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
chr5_+_158737824 0.31 ENST00000521472.1
AC008697.1
AC008697.1
chr16_+_9056563 0.31 ENST00000564485.1
RP11-77H9.8
RP11-77H9.8
chr13_+_53029564 0.30 ENST00000468284.1
ENST00000378034.3
ENST00000258607.5
ENST00000378037.5
CKAP2
cytoskeleton associated protein 2
chr7_+_64838712 0.30 ENST00000328747.7
ENST00000431504.1
ENST00000357512.2
ZNF92
zinc finger protein 92
chr12_+_104337515 0.30 ENST00000550595.1
HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr2_+_161993465 0.30 ENST00000457476.1
TANK
TRAF family member-associated NFKB activator
chr2_+_161993412 0.29 ENST00000259075.2
ENST00000432002.1
TANK
TRAF family member-associated NFKB activator
chr7_+_64838786 0.29 ENST00000450302.2
ZNF92
zinc finger protein 92
chr9_-_73029540 0.28 ENST00000377126.2
KLF9
Kruppel-like factor 9
chr12_-_88535747 0.28 ENST00000309041.7
CEP290
centrosomal protein 290kDa
chr17_+_19091325 0.26 ENST00000584923.1
SNORD3A
small nucleolar RNA, C/D box 3A
chr1_+_219347186 0.26 ENST00000366928.5
LYPLAL1
lysophospholipase-like 1
chr15_+_71185148 0.26 ENST00000443425.2
ENST00000560755.1
LRRC49
leucine rich repeat containing 49
chr12_-_66524482 0.26 ENST00000446587.2
ENST00000266604.2
LLPH
LLP homolog, long-term synaptic facilitation (Aplysia)
chr16_-_66907139 0.26 ENST00000561579.2
NAE1
NEDD8 activating enzyme E1 subunit 1
chr6_-_10694766 0.25 ENST00000460742.2
ENST00000259983.3
ENST00000379586.1
C6orf52
chromosome 6 open reading frame 52
chr15_-_71184724 0.25 ENST00000560604.1
THAP10
THAP domain containing 10
chr4_-_129491686 0.25 ENST00000514265.1
RP11-184M15.1
RP11-184M15.1
chr22_+_29168652 0.25 ENST00000249064.4
ENST00000444523.1
ENST00000448492.2
ENST00000421503.2
CCDC117
coiled-coil domain containing 117
chr4_-_39367949 0.24 ENST00000503784.1
ENST00000349703.2
ENST00000381897.1
RFC1
replication factor C (activator 1) 1, 145kDa
chr5_-_176433693 0.24 ENST00000507513.1
ENST00000511320.1
UIMC1
ubiquitin interaction motif containing 1
chr12_-_10007448 0.24 ENST00000538152.1
CLEC2B
C-type lectin domain family 2, member B
chr4_+_70894130 0.23 ENST00000526767.1
ENST00000530128.1
ENST00000381057.3
HTN3
histatin 3
chr11_-_104480019 0.23 ENST00000536529.1
ENST00000545630.1
ENST00000538641.1
RP11-886D15.1
RP11-886D15.1
chr15_+_71184931 0.23 ENST00000560369.1
ENST00000260382.5
LRRC49
leucine rich repeat containing 49
chr4_-_74964904 0.23 ENST00000508487.2
CXCL2
chemokine (C-X-C motif) ligand 2
chr5_+_169011033 0.23 ENST00000513795.1
SPDL1
spindle apparatus coiled-coil protein 1
chr11_-_107328527 0.22 ENST00000282251.5
ENST00000433523.1
CWF19L2
CWF19-like 2, cell cycle control (S. pombe)
chr12_+_28299014 0.22 ENST00000538586.1
ENST00000536154.1
CCDC91
coiled-coil domain containing 91
chr10_-_38146965 0.22 ENST00000395873.3
ENST00000357328.4
ENST00000395874.2
ZNF248
zinc finger protein 248
chr14_-_64846033 0.21 ENST00000556556.1
CTD-2555O16.1
CTD-2555O16.1
chr10_-_98347063 0.21 ENST00000443638.1
TM9SF3
transmembrane 9 superfamily member 3
chr3_-_179322436 0.21 ENST00000392659.2
ENST00000476781.1
MRPL47
mitochondrial ribosomal protein L47
chr2_+_173955327 0.20 ENST00000422149.1
MLTK
Mitogen-activated protein kinase kinase kinase MLT
chr2_+_201450591 0.20 ENST00000374700.2
AOX1
aldehyde oxidase 1
chr12_+_67663056 0.20 ENST00000545606.1
CAND1
cullin-associated and neddylation-dissociated 1
chr11_-_102668879 0.18 ENST00000315274.6
MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr5_+_93954358 0.18 ENST00000504099.1
ANKRD32
ankyrin repeat domain 32
chr19_+_21265028 0.18 ENST00000291770.7
ZNF714
zinc finger protein 714
chr1_+_63989004 0.18 ENST00000371088.4
EFCAB7
EF-hand calcium binding domain 7
chr11_+_111896090 0.18 ENST00000393051.1
DLAT
dihydrolipoamide S-acetyltransferase
chr1_+_178694300 0.18 ENST00000367635.3
RALGPS2
Ral GEF with PH domain and SH3 binding motif 2
chr22_+_38035459 0.17 ENST00000357436.4
SH3BP1
SH3-domain binding protein 1
chr3_+_99979828 0.17 ENST00000485687.1
ENST00000344949.5
ENST00000394144.4
TBC1D23
TBC1 domain family, member 23
chr1_-_246670614 0.17 ENST00000403792.3
SMYD3
SET and MYND domain containing 3
chr15_-_79576156 0.17 ENST00000560452.1
ENST00000560872.1
ENST00000560732.1
ENST00000559979.1
ENST00000560533.1
ENST00000559225.1
RP11-17L5.4
RP11-17L5.4
chr11_+_127140956 0.17 ENST00000608214.1
RP11-480C22.1
RP11-480C22.1
chr3_-_179322416 0.17 ENST00000259038.2
MRPL47
mitochondrial ribosomal protein L47
chr12_+_32832134 0.17 ENST00000452533.2
DNM1L
dynamin 1-like
chr2_-_201753717 0.17 ENST00000409264.2
PPIL3
peptidylprolyl isomerase (cyclophilin)-like 3
chr7_-_27169801 0.16 ENST00000511914.1
HOXA4
homeobox A4
chr3_-_19975665 0.16 ENST00000295824.9
ENST00000389256.4
EFHB
EF-hand domain family, member B
chr3_-_98241598 0.16 ENST00000513287.1
ENST00000514537.1
ENST00000508071.1
ENST00000507944.1
CLDND1
claudin domain containing 1
chr10_-_74856608 0.16 ENST00000307116.2
ENST00000373008.2
ENST00000412021.2
ENST00000394890.2
ENST00000263556.3
ENST00000440381.1
P4HA1
prolyl 4-hydroxylase, alpha polypeptide I
chr8_+_16884740 0.16 ENST00000318063.5
MICU3
mitochondrial calcium uptake family, member 3
chr7_+_138915102 0.15 ENST00000486663.1
UBN2
ubinuclein 2
chr3_-_25706368 0.15 ENST00000424225.1
TOP2B
topoisomerase (DNA) II beta 180kDa
chr11_-_3400442 0.15 ENST00000429541.2
ENST00000532539.1
ZNF195
zinc finger protein 195
chr1_+_149230680 0.15 ENST00000443018.1
RP11-403I13.5
RP11-403I13.5
chr5_+_138678131 0.15 ENST00000394795.2
ENST00000510080.1
PAIP2
poly(A) binding protein interacting protein 2
chr14_+_31028348 0.15 ENST00000550944.1
ENST00000438909.2
ENST00000553504.1
G2E3
G2/M-phase specific E3 ubiquitin protein ligase
chr3_+_179322573 0.14 ENST00000493866.1
ENST00000472629.1
ENST00000482604.1
NDUFB5
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa
chr14_-_50319482 0.14 ENST00000546046.1
ENST00000555970.1
ENST00000554626.1
ENST00000545773.1
ENST00000556672.1
NEMF
nuclear export mediator factor
chr8_+_33613265 0.14 ENST00000517292.1
RP11-317N12.1
RP11-317N12.1
chr14_-_35591156 0.14 ENST00000554361.1
PPP2R3C
protein phosphatase 2, regulatory subunit B'', gamma
chr18_+_9103957 0.14 ENST00000400033.1
NDUFV2
NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa
chr4_-_111120334 0.14 ENST00000503885.1
ELOVL6
ELOVL fatty acid elongase 6
chr3_+_179322481 0.14 ENST00000259037.3
NDUFB5
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa
chr1_+_158975744 0.14 ENST00000426592.2
IFI16
interferon, gamma-inducible protein 16
chr12_-_95945246 0.14 ENST00000258499.3
USP44
ubiquitin specific peptidase 44
chr1_-_101491319 0.14 ENST00000342173.7
ENST00000488176.1
ENST00000370109.3
DPH5
diphthamide biosynthesis 5
chr2_+_67624430 0.13 ENST00000272342.5
ETAA1
Ewing tumor-associated antigen 1
chr12_+_32832203 0.13 ENST00000553257.1
ENST00000549701.1
ENST00000358214.5
ENST00000266481.6
ENST00000551476.1
ENST00000550154.1
ENST00000547312.1
ENST00000414834.2
ENST00000381000.4
ENST00000548750.1
DNM1L
dynamin 1-like
chr2_+_234526272 0.13 ENST00000373450.4
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A8
chr12_+_123259063 0.13 ENST00000392441.4
ENST00000539171.1
CCDC62
coiled-coil domain containing 62
chr3_+_32737027 0.13 ENST00000454516.2
CNOT10
CCR4-NOT transcription complex, subunit 10
chr15_+_79166065 0.12 ENST00000559690.1
ENST00000559158.1
MORF4L1
mortality factor 4 like 1
chr12_-_13248598 0.12 ENST00000337630.6
ENST00000545699.1
GSG1
germ cell associated 1
chr17_-_79359154 0.12 ENST00000572077.1
RP11-1055B8.3
RP11-1055B8.3
chr2_+_55746746 0.12 ENST00000406691.3
ENST00000349456.4
ENST00000407816.3
ENST00000403007.3
CCDC104
coiled-coil domain containing 104
chr14_-_50319758 0.12 ENST00000298310.5
NEMF
nuclear export mediator factor
chr6_+_64281906 0.12 ENST00000370651.3
PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr17_+_56769924 0.12 ENST00000461271.1
ENST00000583539.1
ENST00000337432.4
ENST00000421782.2
RAD51C
RAD51 paralog C
chr5_-_65018834 0.12 ENST00000506816.1
SGTB
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr11_+_111896320 0.12 ENST00000531306.1
ENST00000537636.1
DLAT
dihydrolipoamide S-acetyltransferase
chr21_+_17214724 0.12 ENST00000449491.1
USP25
ubiquitin specific peptidase 25
chr9_-_124976185 0.12 ENST00000464484.2
LHX6
LIM homeobox 6
chr4_-_156298087 0.12 ENST00000311277.4
MAP9
microtubule-associated protein 9
chr1_+_199996702 0.12 ENST00000367362.3
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr1_+_100818009 0.12 ENST00000370125.2
ENST00000361544.6
ENST00000370124.3
CDC14A
cell division cycle 14A
chr12_+_104697504 0.12 ENST00000527879.1
EID3
EP300 interacting inhibitor of differentiation 3
chr20_-_44540686 0.11 ENST00000477313.1
ENST00000542937.1
ENST00000372431.3
ENST00000354050.4
ENST00000420868.2
PLTP
phospholipid transfer protein
chr1_+_199996733 0.11 ENST00000236914.3
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr22_+_22723969 0.11 ENST00000390295.2
IGLV7-46
immunoglobulin lambda variable 7-46 (gene/pseudogene)
chr7_+_94536514 0.11 ENST00000413325.1
PPP1R9A
protein phosphatase 1, regulatory subunit 9A
chr15_-_55657428 0.11 ENST00000568543.1
CCPG1
cell cycle progression 1
chr8_-_66701319 0.11 ENST00000379419.4
PDE7A
phosphodiesterase 7A
chr15_+_72410629 0.11 ENST00000340912.4
ENST00000544171.1
SENP8
SUMO/sentrin specific peptidase family member 8
chr3_-_131221790 0.11 ENST00000512877.1
ENST00000264995.3
ENST00000511168.1
ENST00000425847.2
MRPL3
mitochondrial ribosomal protein L3
chr7_-_112758665 0.11 ENST00000397764.3
LINC00998
long intergenic non-protein coding RNA 998
chr10_-_1071796 0.10 ENST00000277517.1
IDI2
isopentenyl-diphosphate delta isomerase 2
chr14_-_22005197 0.10 ENST00000541965.1
SALL2
spalt-like transcription factor 2
chr6_+_71122974 0.10 ENST00000418814.2
FAM135A
family with sequence similarity 135, member A
chr13_+_52586517 0.10 ENST00000523764.1
ENST00000521508.1
ALG11
ALG11, alpha-1,2-mannosyltransferase
chr5_-_176433582 0.10 ENST00000506128.1
UIMC1
ubiquitin interaction motif containing 1
chr4_+_110354928 0.10 ENST00000504968.2
ENST00000399100.2
ENST00000265175.5
SEC24B
SEC24 family member B
chr4_+_26585686 0.10 ENST00000505206.1
ENST00000511789.1
TBC1D19
TBC1 domain family, member 19
chr6_+_108616243 0.10 ENST00000421954.1
LACE1
lactation elevated 1
chr12_-_110939870 0.10 ENST00000447578.2
ENST00000546588.1
ENST00000360579.7
ENST00000549970.1
ENST00000549578.1
VPS29
vacuolar protein sorting 29 homolog (S. cerevisiae)
chr3_-_195310802 0.10 ENST00000421243.1
ENST00000453131.1
APOD
apolipoprotein D
chr13_+_78315528 0.10 ENST00000496045.1
SLAIN1
SLAIN motif family, member 1
chr2_+_234545092 0.10 ENST00000344644.5
UGT1A10
UDP glucuronosyltransferase 1 family, polypeptide A10
chr2_+_37571845 0.10 ENST00000537448.1
QPCT
glutaminyl-peptide cyclotransferase
chr15_+_66797455 0.10 ENST00000446801.2
ZWILCH
zwilch kinetochore protein
chr4_+_48833312 0.09 ENST00000508293.1
ENST00000513391.2
OCIAD1
OCIA domain containing 1
chr4_-_141348999 0.09 ENST00000325617.5
CLGN
calmegin
chr19_-_23941680 0.09 ENST00000402377.3
ZNF681
zinc finger protein 681
chr12_+_28605426 0.09 ENST00000542801.1
CCDC91
coiled-coil domain containing 91
chr8_-_82608409 0.09 ENST00000518568.1
SLC10A5
solute carrier family 10, member 5
chr19_+_21579908 0.09 ENST00000596302.1
ENST00000392288.2
ENST00000594390.1
ENST00000355504.4
ZNF493
zinc finger protein 493
chr12_+_10658201 0.09 ENST00000322446.3
EIF2S3L
Putative eukaryotic translation initiation factor 2 subunit 3-like protein
chr13_+_34392200 0.09 ENST00000434425.1
RFC3
replication factor C (activator 1) 3, 38kDa
chr4_-_70080449 0.09 ENST00000446444.1
UGT2B11
UDP glucuronosyltransferase 2 family, polypeptide B11
chr5_+_93954039 0.09 ENST00000265140.5
ANKRD32
ankyrin repeat domain 32
chr8_+_121925301 0.09 ENST00000517739.1
RP11-369K17.1
RP11-369K17.1
chr1_-_26231589 0.09 ENST00000374291.1
STMN1
stathmin 1
chr12_-_30848914 0.09 ENST00000256079.4
IPO8
importin 8
chr15_+_66797627 0.09 ENST00000565627.1
ENST00000564179.1
ZWILCH
zwilch kinetochore protein
chr19_+_7413835 0.09 ENST00000576789.1
CTB-133G6.1
CTB-133G6.1
chr5_+_56471592 0.09 ENST00000511209.1
GPBP1
GC-rich promoter binding protein 1
chr9_-_88896977 0.09 ENST00000311534.6
ISCA1
iron-sulfur cluster assembly 1
chr4_-_129208030 0.09 ENST00000503872.1
PGRMC2
progesterone receptor membrane component 2
chr9_+_125703282 0.09 ENST00000373647.4
ENST00000402311.1
RABGAP1
RAB GTPase activating protein 1
chr4_-_111120132 0.09 ENST00000506625.1
ELOVL6
ELOVL fatty acid elongase 6
chr10_+_31608054 0.09 ENST00000320985.10
ENST00000361642.5
ENST00000560721.2
ENST00000558440.1
ENST00000424869.1
ENST00000542815.3
ZEB1
zinc finger E-box binding homeobox 1
chr13_-_79233314 0.08 ENST00000282003.6
RNF219
ring finger protein 219
chr3_-_165555200 0.08 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
BCHE
butyrylcholinesterase
chr2_+_101869262 0.08 ENST00000289382.3
CNOT11
CCR4-NOT transcription complex, subunit 11
chr6_-_656963 0.08 ENST00000380907.2
HUS1B
HUS1 checkpoint homolog b (S. pombe)
chr4_-_129207942 0.08 ENST00000503588.1
PGRMC2
progesterone receptor membrane component 2
chr2_-_136594740 0.08 ENST00000264162.2
LCT
lactase
chr7_-_112758589 0.08 ENST00000413744.1
ENST00000439551.1
ENST00000441359.1
LINC00998
long intergenic non-protein coding RNA 998
chr5_+_145718587 0.08 ENST00000230732.4
POU4F3
POU class 4 homeobox 3
chr4_-_111119804 0.08 ENST00000394607.3
ENST00000302274.3
ELOVL6
ELOVL fatty acid elongase 6
chr8_-_80942061 0.08 ENST00000519386.1
MRPS28
mitochondrial ribosomal protein S28
chr13_-_29293058 0.08 ENST00000380814.4
SLC46A3
solute carrier family 46, member 3
chr6_-_28554977 0.08 ENST00000452236.2
SCAND3
SCAN domain containing 3
chr3_+_138327417 0.08 ENST00000338446.4
FAIM
Fas apoptotic inhibitory molecule
chr8_+_107738240 0.08 ENST00000449762.2
ENST00000297447.6
OXR1
oxidation resistance 1
chr2_+_61372226 0.08 ENST00000426997.1
C2orf74
chromosome 2 open reading frame 74
chr14_+_24702073 0.08 ENST00000399440.2
GMPR2
guanosine monophosphate reductase 2
chr19_+_42212526 0.08 ENST00000598976.1
ENST00000435837.2
ENST00000221992.6
ENST00000405816.1
CEA
CEACAM5
Uncharacterized protein
carcinoembryonic antigen-related cell adhesion molecule 5
chr4_+_122722466 0.08 ENST00000243498.5
ENST00000379663.3
ENST00000509800.1
EXOSC9
exosome component 9
chr5_+_140767452 0.08 ENST00000519479.1
PCDHGB4
protocadherin gamma subfamily B, 4
chr3_+_132036207 0.08 ENST00000336375.5
ENST00000495911.1
ACPP
acid phosphatase, prostate
chr6_-_106773491 0.08 ENST00000360666.4
ATG5
autophagy related 5
chr10_+_12238171 0.08 ENST00000378900.2
ENST00000442050.1
CDC123
cell division cycle 123
chr17_+_34890807 0.08 ENST00000429467.2
ENST00000592983.1
PIGW
phosphatidylinositol glycan anchor biosynthesis, class W
chr17_+_71228793 0.08 ENST00000426147.2
C17orf80
chromosome 17 open reading frame 80
chr3_-_196911002 0.08 ENST00000452595.1
DLG1
discs, large homolog 1 (Drosophila)
chr14_+_24702127 0.08 ENST00000557854.1
ENST00000348719.7
ENST00000559104.1
ENST00000456667.3
GMPR2
guanosine monophosphate reductase 2
chr10_+_6625733 0.07 ENST00000607982.1
ENST00000608526.1
PRKCQ-AS1
PRKCQ antisense RNA 1
chr12_+_90313394 0.07 ENST00000549551.1
RP11-654D12.2
RP11-654D12.2
chr17_+_71228740 0.07 ENST00000268942.8
ENST00000359042.2
C17orf80
chromosome 17 open reading frame 80
chr9_-_77502636 0.07 ENST00000449912.2
TRPM6
transient receptor potential cation channel, subfamily M, member 6
chr12_-_15114191 0.07 ENST00000541380.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr3_+_137906154 0.07 ENST00000466749.1
ENST00000358441.2
ENST00000489213.1
ARMC8
armadillo repeat containing 8
chr17_-_191188 0.07 ENST00000575634.1
RPH3AL
rabphilin 3A-like (without C2 domains)
chr11_+_36616044 0.07 ENST00000334307.5
ENST00000531554.1
ENST00000347206.4
ENST00000534635.1
ENST00000446510.2
ENST00000530697.1
ENST00000527108.1
C11orf74
chromosome 11 open reading frame 74
chr4_+_48833234 0.07 ENST00000510824.1
ENST00000425583.2
OCIAD1
OCIA domain containing 1
chr7_+_138145145 0.07 ENST00000415680.2
TRIM24
tripartite motif containing 24
chr13_+_113030658 0.07 ENST00000414180.1
ENST00000443541.1
SPACA7
sperm acrosome associated 7
chr6_-_110011718 0.07 ENST00000532976.1
AK9
adenylate kinase 9
chr13_+_34392185 0.07 ENST00000380071.3
RFC3
replication factor C (activator 1) 3, 38kDa
chr3_+_138327542 0.07 ENST00000360570.3
ENST00000393035.2
FAIM
Fas apoptotic inhibitory molecule
chr14_+_24701819 0.07 ENST00000560139.1
ENST00000559910.1
GMPR2
guanosine monophosphate reductase 2
chr1_+_156308245 0.07 ENST00000368253.2
ENST00000470342.1
ENST00000368254.1
TSACC
TSSK6 activating co-chaperone
chr4_-_114682224 0.06 ENST00000342666.5
ENST00000515496.1
ENST00000514328.1
ENST00000508738.1
ENST00000379773.2
CAMK2D
calcium/calmodulin-dependent protein kinase II delta
chr12_-_15114658 0.06 ENST00000542276.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr2_-_201753980 0.06 ENST00000443398.1
ENST00000286175.8
ENST00000409449.1
PPIL3
peptidylprolyl isomerase (cyclophilin)-like 3
chr10_-_12238071 0.06 ENST00000491614.1
ENST00000537776.1
NUDT5
nudix (nucleoside diphosphate linked moiety X)-type motif 5
chrX_-_133792480 0.06 ENST00000359237.4
PLAC1
placenta-specific 1
chr3_+_143690640 0.06 ENST00000315691.3
C3orf58
chromosome 3 open reading frame 58
chr13_+_49551020 0.06 ENST00000541916.1
FNDC3A
fibronectin type III domain containing 3A
chr4_-_69536346 0.06 ENST00000338206.5
UGT2B15
UDP glucuronosyltransferase 2 family, polypeptide B15
chr7_+_154720173 0.06 ENST00000397551.2
PAXIP1-AS2
PAXIP1 antisense RNA 2
chr17_-_26127525 0.06 ENST00000313735.6
NOS2
nitric oxide synthase 2, inducible
chr21_-_46359760 0.06 ENST00000330551.3
ENST00000397841.1
ENST00000380070.4
C21orf67
chromosome 21 open reading frame 67

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXC12_HOXD12

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0006433 glutamyl-tRNA aminoacylation(GO:0006424) prolyl-tRNA aminoacylation(GO:0006433)
0.1 0.3 GO:1900244 synaptic vesicle recycling via endosome(GO:0036466) positive regulation of synaptic vesicle endocytosis(GO:1900244) positive regulation of synaptic vesicle recycling(GO:1903423) positive regulation of synaptic vesicle exocytosis(GO:2000302)
0.1 0.3 GO:0031247 actin rod assembly(GO:0031247)
0.1 0.6 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.7 GO:0002084 protein depalmitoylation(GO:0002084)
0.1 0.2 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.0 0.2 GO:0046110 xanthine metabolic process(GO:0046110)
0.0 0.3 GO:0051414 response to cortisol(GO:0051414)
0.0 0.3 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 0.3 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.2 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.1 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.3 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.3 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.1 GO:0014016 neuroblast differentiation(GO:0014016)
0.0 0.1 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.0 0.1 GO:0070980 biphenyl catabolic process(GO:0070980)
0.0 0.1 GO:0050992 dimethylallyl diphosphate biosynthetic process(GO:0050992) dimethylallyl diphosphate metabolic process(GO:0050993)
0.0 0.3 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.3 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.0 0.1 GO:0051552 flavone metabolic process(GO:0051552)
0.0 0.1 GO:0061565 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.0 0.2 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.2 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.2 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.1 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0 2.0 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.3 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.1 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.1 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.1 GO:0019303 D-ribose catabolic process(GO:0019303)
0.0 0.1 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.0 0.1 GO:0051177 meiotic sister chromatid cohesion(GO:0051177)
0.0 0.1 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.1 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
0.0 0.2 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.6 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.1 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0 0.1 GO:0044034 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.2 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.0 GO:2000646 lipid transport involved in lipid storage(GO:0010877) regulation of Cdc42 protein signal transduction(GO:0032489) NMDA glutamate receptor clustering(GO:0097114) positive regulation of receptor catabolic process(GO:2000646)
0.0 0.2 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.0 GO:0021793 chemorepulsion of branchiomotor axon(GO:0021793)
0.0 0.1 GO:0042360 vitamin E metabolic process(GO:0042360)
0.0 0.0 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.1 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.3 GO:0043101 purine-containing compound salvage(GO:0043101)
0.0 0.1 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.1 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0097452 GAIT complex(GO:0097452)
0.1 0.3 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 0.4 GO:1902560 GMP reductase complex(GO:1902560)
0.0 0.2 GO:1990423 RZZ complex(GO:1990423)
0.0 0.4 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.2 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 0.3 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.1 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.1 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.3 GO:0036038 MKS complex(GO:0036038)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.1 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.0 GO:0034363 intermediate-density lipoprotein particle(GO:0034363) discoidal high-density lipoprotein particle(GO:0034365)
0.0 0.1 GO:0044326 dendritic spine neck(GO:0044326)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0004827 glutamate-tRNA ligase activity(GO:0004818) proline-tRNA ligase activity(GO:0004827)
0.2 1.9 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.3 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.1 0.3 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.1 0.6 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.2 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.1 0.4 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.1 0.2 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.7 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.4 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.3 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.1 GO:0033265 choline binding(GO:0033265)
0.0 0.3 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.1 GO:0004452 isopentenyl-diphosphate delta-isomerase activity(GO:0004452)
0.0 0.3 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.1 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.2 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.2 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.0 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.0 0.3 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.1 GO:0034617 nitric-oxide synthase activity(GO:0004517) tetrahydrobiopterin binding(GO:0034617)
0.0 0.0 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.0 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.3 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.0 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.1 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.3 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 1.9 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.8 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.5 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.2 REACTOME POL SWITCHING Genes involved in Polymerase switching