ISMARA results: HIVEP1

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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HIVEP1

Z-value: 1.00

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Transcription factors associated with HIVEP1

Gene Symbol	Gene ID	Gene Info
HIVEP1 Ensembl NCBI GeneCards UniProt	ENSG00000095951.12	HIVEP zinc finger 1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
HIVEP1	hg19_v2_chr6_+_12008986_12009016	-0.43	3.9e-01	Click!

Activity profile of HIVEP1 motif

Sorted Z-values of HIVEP1 motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr19_+_54135310 Show fit	0.73	ENST00000376650.1	DPRX Ensembl NCBI GeneCards UniProt Show fit	divergent-paired related homeobox
chr14_+_38065052 Show fit	0.53	ENST00000556845.1	TTC6 Ensembl NCBI GeneCards UniProt Show fit	tetratricopeptide repeat domain 6
chr12_-_106697974 Show fit	0.51	ENST00000553039.1	CKAP4 Ensembl NCBI GeneCards UniProt Show fit	cytoskeleton-associated protein 4
chr11_+_19799327 Show fit	0.46	ENST00000540292.1	NAV2 Ensembl NCBI GeneCards UniProt Show fit	neuron navigator 2
chr3_+_119814070 Show fit	0.46	ENST00000469070.1	RP11-18H7.1 Ensembl NCBI GeneCards UniProt Show fit	RP11-18H7.1
chr19_-_46272462 Show fit	0.41	ENST00000317578.6	SIX5 Ensembl NCBI GeneCards UniProt Show fit	SIX homeobox 5
chr18_-_2982869 Show fit	0.39	ENST00000584915.1	LPIN2 Ensembl NCBI GeneCards UniProt Show fit	lipin 2
chr9_+_97562440 Show fit	0.39	ENST00000395357.2	C9orf3 Ensembl NCBI GeneCards UniProt Show fit	chromosome 9 open reading frame 3
chr20_+_1115821 Show fit	0.37	ENST00000435720.1	PSMF1 Ensembl NCBI GeneCards UniProt Show fit	proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr9_-_130477912 Show fit	0.36	ENST00000543175.1	PTRH1 Ensembl NCBI GeneCards UniProt Show fit	peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae)

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of HIVEP1

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.9	GO:0019264	glycine biosynthetic process from serine(GO:0019264)
0.2	0.8	GO:1901545	cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545)
0.1	0.8	GO:0003025	regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
0.0	0.7	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
0.0	0.7	GO:0051639	actin filament network formation(GO:0051639)
0.2	0.5	GO:0070446	cellular response to caloric restriction(GO:0061433) negative regulation of oligodendrocyte progenitor proliferation(GO:0070446)
0.1	0.5	GO:0046449	allantoin metabolic process(GO:0000255) creatinine metabolic process(GO:0046449)
0.0	0.5	GO:2000002	negative regulation of DNA damage checkpoint(GO:2000002)
0.0	0.5	GO:0006701	progesterone biosynthetic process(GO:0006701)
0.0	0.5	GO:0006995	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)

Showing 1 to 10 of 113 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.9	GO:0070552	BRISC complex(GO:0070552)
0.1	0.9	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	0.9	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.8	GO:0032590	dendrite membrane(GO:0032590)
0.0	0.7	GO:0005916	fascia adherens(GO:0005916)
0.0	0.5	GO:0000445	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0	0.5	GO:0042599	lamellar body(GO:0042599)
0.0	0.5	GO:0005839	proteasome core complex(GO:0005839)
0.1	0.4	GO:1990682	CSF1-CSF1R complex(GO:1990682)
0.0	0.4	GO:0035631	CD40 receptor complex(GO:0035631)

Showing 1 to 10 of 39 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.0	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1	0.9	GO:0004372	glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.0	0.8	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.0	0.7	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.7	GO:0017166	vinculin binding(GO:0017166)
0.2	0.5	GO:0046970	NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.1	0.5	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.0	0.5	GO:0030957	Tat protein binding(GO:0030957)
0.0	0.5	GO:0017127	cholesterol transporter activity(GO:0017127)
0.0	0.5	GO:0070628	proteasome binding(GO:0070628)

Showing 1 to 10 of 65 entries

Gene overrepresentation in C2:CP category:

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Total log-likelihood	Term	Description
0.8	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.7	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.5	PID IL5 PATHWAY	IL5-mediated signaling events
0.4	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.3	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1	PID IL23 PATHWAY	IL23-mediated signaling events
0.0	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway

Showing 1 to 7 of 7 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Total log-likelihood	Term	Description
0.8	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.7	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.7	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.6	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.5	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.5	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.5	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.4	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.3	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.3	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors

Showing 1 to 10 of 14 entries

Results for HIVEP1

Z-value: 1.00

Motif logo

Transcription factors associated with HIVEP1

Activity-expression correlation:

Activity profile of HIVEP1 motif

Sorted Z-values of HIVEP1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of HIVEP1

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: