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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HIF1A

Z-value: 1.82

Motif logo

Transcription factors associated with HIF1A

Gene Symbol Gene ID Gene Info
ENSG00000100644.12 hypoxia inducible factor 1 subunit alpha

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HIF1Ahg19_v2_chr14_+_62164340_621644430.843.5e-02Click!

Activity profile of HIF1A motif

Sorted Z-values of HIF1A motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_150254936 4.72 ENST00000447007.1
ENST00000369095.1
ENST00000369094.1
chromosome 1 open reading frame 51
chr14_+_64970427 2.91 ENST00000553583.1
zinc finger and BTB domain containing 1
chr14_+_64970662 2.23 ENST00000556965.1
ENST00000554015.1
zinc finger and BTB domain containing 1
chr3_-_145878954 2.02 ENST00000282903.5
ENST00000360060.3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr12_+_112451222 1.74 ENST00000552052.1
endoplasmic reticulum protein 29
chr19_-_17622269 1.63 ENST00000595116.1
CTD-3131K8.2
chr14_+_56046990 1.54 ENST00000438792.2
ENST00000395314.3
ENST00000395308.1
kinectin 1 (kinesin receptor)
chr14_-_62217779 1.51 ENST00000554254.1
HIF1A antisense RNA 2
chr1_+_92495528 1.50 ENST00000370383.4
epoxide hydrolase 4
chr1_+_100436065 1.43 ENST00000370153.1
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
chr4_-_4291761 1.33 ENST00000513174.1
Ly1 antibody reactive
chr4_+_17578815 1.28 ENST00000226299.4
leucine aminopeptidase 3
chr6_+_89791507 1.25 ENST00000354922.3
proline-rich nuclear receptor coactivator 1
chr3_-_52719888 1.18 ENST00000458294.1
polybromo 1
chr14_+_56046914 1.16 ENST00000413890.2
ENST00000395309.3
ENST00000554567.1
ENST00000555498.1
kinectin 1 (kinesin receptor)
chr5_+_49962495 1.14 ENST00000515175.1
poly (ADP-ribose) polymerase family, member 8
chr1_+_100435535 1.03 ENST00000427993.2
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
chr8_+_26240666 1.01 ENST00000523949.1
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr1_-_8939265 1.00 ENST00000489867.1
enolase 1, (alpha)
chr8_-_97273807 1.00 ENST00000517720.1
ENST00000287025.3
ENST00000523821.1
MTERF domain containing 1
chr13_-_52027134 0.99 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
integrator complex subunit 6
chr4_-_104119528 0.99 ENST00000380026.3
ENST00000503705.1
ENST00000265148.3
centromere protein E, 312kDa
chr7_+_26331678 0.97 ENST00000446848.2
sorting nexin 10
chr8_+_26240414 0.95 ENST00000380629.2
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr8_+_109455845 0.95 ENST00000220853.3
ER membrane protein complex subunit 2
chr7_-_127032363 0.93 ENST00000393312.1
zinc finger protein 800
chr1_+_74663994 0.93 ENST00000472069.1
fucose-1-phosphate guanylyltransferase
chr7_-_27170352 0.93 ENST00000428284.2
ENST00000360046.5
homeobox A4
chr6_+_151773583 0.92 ENST00000545879.1
chromosome 6 open reading frame 211
chr8_-_125551278 0.91 ENST00000519232.1
ENST00000523888.1
ENST00000522810.1
ENST00000519548.1
ENST00000517678.1
ENST00000605953.1
ENST00000276692.6
TatD DNase domain containing 1
chr4_+_76649797 0.89 ENST00000538159.1
ENST00000514213.2
USO1 vesicle transport factor
chr16_-_81129951 0.89 ENST00000315467.3
glycine cleavage system protein H (aminomethyl carrier)
chr8_+_17354587 0.84 ENST00000494857.1
ENST00000522656.1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr1_-_26233423 0.82 ENST00000357865.2
stathmin 1
chr1_-_113498616 0.80 ENST00000433570.4
ENST00000538576.1
ENST00000458229.1
solute carrier family 16 (monocarboxylate transporter), member 1
chr7_+_96747030 0.79 ENST00000360382.4
ACN9 homolog (S. cerevisiae)
chr3_+_19988885 0.79 ENST00000422242.1
RAB5A, member RAS oncogene family
chr14_-_92572894 0.78 ENST00000532032.1
ENST00000506466.1
ENST00000555381.1
ENST00000557311.1
ENST00000554592.1
ENST00000554672.1
ENST00000553491.1
ENST00000556220.1
ENST00000502250.1
ENST00000503767.1
ENST00000393287.5
ENST00000340660.6
ENST00000545170.1
ENST00000429774.2
ataxin 3
chr18_+_56531584 0.78 ENST00000590287.1
zinc finger protein 532
chr8_+_17354617 0.77 ENST00000470360.1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr8_+_95908041 0.77 ENST00000396113.1
ENST00000519136.1
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr1_+_65613852 0.76 ENST00000327299.7
adenylate kinase 4
chr2_+_187350883 0.76 ENST00000337859.6
zinc finger CCCH-type containing 15
chr15_+_74218787 0.75 ENST00000261921.7
lysyl oxidase-like 1
chr1_+_186798073 0.75 ENST00000367466.3
ENST00000442353.2
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr15_+_52311398 0.74 ENST00000261845.5
mitogen-activated protein kinase 6
chr7_-_127032114 0.74 ENST00000436992.1
zinc finger protein 800
chr8_+_109455830 0.73 ENST00000524143.1
ER membrane protein complex subunit 2
chr3_+_100211412 0.72 ENST00000323523.4
ENST00000403410.1
ENST00000449609.1
transmembrane protein 45A
chr11_-_14665163 0.71 ENST00000418988.2
proteasome (prosome, macropain) subunit, alpha type, 1
chr2_+_187350973 0.70 ENST00000544130.1
zinc finger CCCH-type containing 15
chr6_-_56112235 0.70 ENST00000370817.3
collagen, type XXI, alpha 1
chr11_-_46141338 0.70 ENST00000529782.1
ENST00000532010.1
ENST00000525438.1
ENST00000533757.1
ENST00000527782.1
PHD finger protein 21A
chr1_-_6259641 0.69 ENST00000234875.4
ribosomal protein L22
chr5_+_61602236 0.68 ENST00000514082.1
ENST00000407818.3
kinesin heavy chain member 2A
chr7_+_86781677 0.68 ENST00000331242.7
ENST00000394702.3
ENST00000413276.2
ENST00000446796.2
ENST00000411766.2
ENST00000420131.1
ENST00000414630.2
ENST00000453049.1
ENST00000428819.1
ENST00000448598.1
ENST00000449088.3
ENST00000430405.3
cyclin D binding myb-like transcription factor 1
chr6_+_87865262 0.67 ENST00000369577.3
ENST00000518845.1
ENST00000339907.4
ENST00000496806.2
zinc finger protein 292
chr14_-_54908043 0.67 ENST00000556113.1
ENST00000553660.1
ENST00000395573.4
ENST00000557690.1
ENST00000216416.4
cornichon family AMPA receptor auxiliary protein 1
chr4_-_104119488 0.67 ENST00000514974.1
centromere protein E, 312kDa
chr18_-_45457478 0.67 ENST00000402690.2
ENST00000356825.4
SMAD family member 2
chr2_+_118846008 0.66 ENST00000245787.4
insulin induced gene 2
chr14_+_96968707 0.66 ENST00000216277.8
ENST00000557320.1
ENST00000557471.1
poly(A) polymerase alpha
chr1_-_92351666 0.65 ENST00000465892.2
ENST00000417833.2
transforming growth factor, beta receptor III
chr16_-_81129845 0.64 ENST00000569885.1
ENST00000566566.1
glycine cleavage system protein H (aminomethyl carrier)
chr12_+_131356582 0.64 ENST00000448750.3
ENST00000541630.1
ENST00000392369.2
ENST00000254675.3
ENST00000535090.1
ENST00000392367.3
RAN, member RAS oncogene family
chr12_+_28343365 0.62 ENST00000545336.1
coiled-coil domain containing 91
chr12_+_28343353 0.62 ENST00000539107.1
coiled-coil domain containing 91
chr17_-_67323305 0.61 ENST00000392677.2
ENST00000593153.1
ATP-binding cassette, sub-family A (ABC1), member 5
chr17_+_7608511 0.61 ENST00000226091.2
ephrin-B3
chr6_-_114292449 0.60 ENST00000519065.1
histone deacetylase 2
chr6_-_114292284 0.60 ENST00000520895.1
ENST00000521163.1
ENST00000524334.1
ENST00000368632.2
ENST00000398283.2
histone deacetylase 2
chr13_-_36788718 0.59 ENST00000317764.6
ENST00000379881.3
spermatogenesis and oogenesis specific basic helix-loop-helix 2
chr1_-_166136187 0.58 ENST00000338353.3
family with sequence similarity 78, member B
chr14_-_53162361 0.57 ENST00000395686.3
ERO1-like (S. cerevisiae)
chr3_-_195808952 0.56 ENST00000540528.1
ENST00000392396.3
ENST00000535031.1
ENST00000420415.1
transferrin receptor
chr3_-_149688971 0.56 ENST00000498307.1
ENST00000489155.1
profilin 2
chr1_-_113498943 0.55 ENST00000369626.3
solute carrier family 16 (monocarboxylate transporter), member 1
chr1_-_166135952 0.55 ENST00000354422.3
family with sequence similarity 78, member B
chr1_+_14026671 0.55 ENST00000484063.2
PR domain containing 2, with ZNF domain
chr6_+_64282447 0.55 ENST00000370650.2
ENST00000578299.1
protein tyrosine phosphatase type IVA, member 1
chr14_+_96968802 0.54 ENST00000556619.1
ENST00000392990.2
poly(A) polymerase alpha
chr10_-_93392811 0.54 ENST00000238994.5
protein phosphatase 1, regulatory subunit 3C
chr1_-_26232951 0.54 ENST00000426559.2
ENST00000455785.2
stathmin 1
chrX_+_16804544 0.54 ENST00000380122.5
ENST00000398155.4
taxilin gamma
chr1_-_6269448 0.53 ENST00000465335.1
ribosomal protein L22
chr15_+_76135622 0.53 ENST00000338677.4
ENST00000267938.4
ENST00000569423.1
ubiquitin-conjugating enzyme E2Q family member 2
chr8_+_6566206 0.53 ENST00000518327.1
1-acylglycerol-3-phosphate O-acyltransferase 5
chr20_-_44540686 0.52 ENST00000477313.1
ENST00000542937.1
ENST00000372431.3
ENST00000354050.4
ENST00000420868.2
phospholipid transfer protein
chr13_-_31038370 0.52 ENST00000399489.1
ENST00000339872.4
high mobility group box 1
chr4_+_76649753 0.52 ENST00000603759.1
USO1 vesicle transport factor
chr5_+_61601965 0.52 ENST00000401507.3
kinesin heavy chain member 2A
chr7_+_86781778 0.51 ENST00000432937.2
cyclin D binding myb-like transcription factor 1
chr3_-_149688896 0.51 ENST00000239940.7
profilin 2
chr11_-_73471655 0.50 ENST00000400470.2
RAB6A, member RAS oncogene family
chr8_+_98656693 0.50 ENST00000519934.1
metadherin
chr6_-_153304148 0.50 ENST00000229758.3
F-box protein 5
chr6_+_35265586 0.50 ENST00000542066.1
ENST00000316637.5
differentially expressed in FDCP 6 homolog (mouse)
chr2_+_216946589 0.50 ENST00000433112.1
ENST00000454545.1
ENST00000437356.2
ENST00000295658.4
ENST00000455479.1
ENST00000406027.2
transmembrane protein 169
chr10_-_75910789 0.50 ENST00000355264.4
adaptor-related protein complex 3, mu 1 subunit
chr1_-_235324530 0.49 ENST00000447801.1
ENST00000366606.3
ENST00000429912.1
RNA binding motif protein 34
chr7_+_26331541 0.49 ENST00000416246.1
ENST00000338523.4
ENST00000412416.1
sorting nexin 10
chr14_-_88459182 0.49 ENST00000544807.2
galactosylceramidase
chr6_+_127588020 0.49 ENST00000309649.3
ENST00000610162.1
ENST00000610153.1
ENST00000608991.1
ENST00000480444.1
ring finger protein 146
chr15_+_89181974 0.49 ENST00000306072.5
interferon stimulated exonuclease gene 20kDa
chr17_+_57642886 0.49 ENST00000251241.4
ENST00000451169.2
ENST00000425628.3
ENST00000584385.1
ENST00000580030.1
DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr8_-_54755459 0.48 ENST00000524234.1
ENST00000521275.1
ENST00000396774.2
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr10_-_44070016 0.48 ENST00000374446.2
ENST00000426961.1
ENST00000535642.1
zinc finger protein 239
chr5_+_138609441 0.48 ENST00000509990.1
ENST00000506147.1
ENST00000512107.1
matrin 3
chr1_-_26232522 0.48 ENST00000399728.1
stathmin 1
chr10_+_75910960 0.48 ENST00000539909.1
ENST00000286621.2
adenosine kinase
chr4_+_78079450 0.48 ENST00000395640.1
ENST00000512918.1
cyclin G2
chr3_-_19988462 0.47 ENST00000344838.4
EF-hand domain family, member B
chr2_+_171627597 0.47 ENST00000429172.1
ENST00000426475.1
AC007405.6
chr17_+_66287628 0.47 ENST00000581639.1
ENST00000452479.2
arylsulfatase G
chr1_-_167522982 0.47 ENST00000370509.4
cellular repressor of E1A-stimulated genes 1
chr5_+_78532003 0.46 ENST00000396137.4
junction mediating and regulatory protein, p53 cofactor
chr8_-_95908902 0.46 ENST00000520509.1
cyclin E2
chr18_+_9913977 0.46 ENST00000400000.2
ENST00000340541.4
VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
chr4_-_54930790 0.46 ENST00000263921.3
cysteine-rich hydrophobic domain 2
chr13_+_25875785 0.46 ENST00000381747.3
nucleoporin like 1
chr2_+_30370382 0.45 ENST00000402708.1
yippee-like 5 (Drosophila)
chr3_+_19988566 0.45 ENST00000273047.4
RAB5A, member RAS oncogene family
chr7_+_94536898 0.44 ENST00000433360.1
ENST00000340694.4
ENST00000424654.1
protein phosphatase 1, regulatory subunit 9A
chr5_+_61602055 0.44 ENST00000381103.2
kinesin heavy chain member 2A
chr6_+_64281906 0.44 ENST00000370651.3
protein tyrosine phosphatase type IVA, member 1
chr2_+_242254753 0.44 ENST00000428524.1
ENST00000445030.1
ENST00000407017.1
septin 2
chr3_-_195808980 0.44 ENST00000360110.4
transferrin receptor
chr12_-_50677255 0.44 ENST00000551691.1
ENST00000394943.3
ENST00000341247.4
LIM domain and actin binding 1
chr10_-_96122682 0.43 ENST00000371361.3
nucleolar complex associated 3 homolog (S. cerevisiae)
chr15_+_89182178 0.43 ENST00000559876.1
interferon stimulated exonuclease gene 20kDa
chr5_-_38845812 0.43 ENST00000513480.1
ENST00000512519.1
CTD-2127H9.1
chr2_+_242254679 0.43 ENST00000428282.1
ENST00000360051.3
septin 2
chr19_-_1237990 0.43 ENST00000382477.2
ENST00000215376.6
ENST00000590083.1
chromosome 19 open reading frame 26
chr17_+_76311791 0.42 ENST00000586321.1
AC061992.2
chr9_+_88556444 0.42 ENST00000376040.1
N(alpha)-acetyltransferase 35, NatC auxiliary subunit
chr8_-_30515693 0.41 ENST00000355904.4
general transcription factor IIE, polypeptide 2, beta 34kDa
chr9_-_94186131 0.41 ENST00000297689.3
nuclear factor, interleukin 3 regulated
chr2_+_242254507 0.41 ENST00000391973.2
septin 2
chr17_+_34890807 0.41 ENST00000429467.2
ENST00000592983.1
phosphatidylinositol glycan anchor biosynthesis, class W
chr2_+_170683979 0.40 ENST00000418381.1
ubiquitin protein ligase E3 component n-recognin 3 (putative)
chr3_+_49044765 0.40 ENST00000429900.2
WD repeat domain 6
chr22_+_41777927 0.40 ENST00000266304.4
thyrotrophic embryonic factor
chr12_+_72148614 0.40 ENST00000261263.3
RAB21, member RAS oncogene family
chr10_+_49514698 0.39 ENST00000432379.1
ENST00000429041.1
ENST00000374189.1
mitogen-activated protein kinase 8
chr3_-_156272924 0.39 ENST00000467789.1
ENST00000265044.2
signal sequence receptor, gamma (translocon-associated protein gamma)
chr14_+_23025534 0.39 ENST00000557595.1
Uncharacterized protein
chr12_-_21810726 0.39 ENST00000396076.1
lactate dehydrogenase B
chr10_+_76970379 0.38 ENST00000344036.4
voltage-dependent anion channel 2
chr19_-_49137762 0.38 ENST00000593500.1
D site of albumin promoter (albumin D-box) binding protein
chr8_-_54755789 0.38 ENST00000359530.2
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr1_+_74663896 0.38 ENST00000370898.3
ENST00000467578.2
ENST00000370894.5
ENST00000482102.2
ENST00000609362.1
ENST00000534056.1
ENST00000557284.2
ENST00000370899.3
ENST00000370895.1
ENST00000534632.1
ENST00000370893.1
ENST00000370891.2
fucose-1-phosphate guanylyltransferase
FPGT-TNNI3K readthrough
TNNI3 interacting kinase
chr12_-_21810765 0.38 ENST00000450584.1
ENST00000350669.1
lactate dehydrogenase B
chr20_+_10015678 0.38 ENST00000378392.1
ENST00000378380.3
ankyrin repeat and EF-hand domain containing 1
chr7_+_94537542 0.38 ENST00000433881.1
protein phosphatase 1, regulatory subunit 9A
chr7_+_86781847 0.38 ENST00000432366.2
ENST00000423590.2
ENST00000394703.5
cyclin D binding myb-like transcription factor 1
chr4_-_492891 0.38 ENST00000338977.5
ENST00000511833.2
zinc finger protein 721
chr3_+_133292759 0.37 ENST00000431519.2
CDV3 homolog (mouse)
chr2_+_28113583 0.37 ENST00000344773.2
ENST00000379624.1
ENST00000342045.2
ENST00000379632.2
ENST00000361704.2
brain and reproductive organ-expressed (TNFRSF1A modulator)
chr22_+_39853258 0.37 ENST00000341184.6
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr11_-_18343725 0.37 ENST00000531848.1
Hermansky-Pudlak syndrome 5
chr1_+_231376941 0.37 ENST00000436239.1
ENST00000366647.4
ENST00000366646.3
ENST00000416000.1
glyceronephosphate O-acyltransferase
chr13_-_28024681 0.36 ENST00000381116.1
ENST00000381120.3
ENST00000431572.2
mitochondrial translational initiation factor 3
chr7_-_102985035 0.36 ENST00000426036.2
ENST00000249270.7
ENST00000454277.1
ENST00000412522.1
DnaJ (Hsp40) homolog, subfamily C, member 2
chr1_+_204797749 0.36 ENST00000367172.4
ENST00000367171.4
ENST00000367170.4
ENST00000338515.6
ENST00000339876.6
ENST00000338586.6
ENST00000539706.1
ENST00000360049.4
ENST00000367169.4
ENST00000446412.1
ENST00000403080.1
neurofascin
chr11_+_76156045 0.36 ENST00000533988.1
ENST00000524490.1
ENST00000334736.3
ENST00000343878.3
ENST00000533972.1
chromosome 11 open reading frame 30
chr7_+_72848092 0.35 ENST00000344575.3
frizzled family receptor 9
chr9_+_4490394 0.35 ENST00000262352.3
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
chr22_+_29279552 0.34 ENST00000544604.2
zinc and ring finger 3
chr13_-_28024269 0.34 ENST00000405591.2
mitochondrial translational initiation factor 3
chr1_-_6259613 0.34 ENST00000465387.1
ribosomal protein L22
chr1_-_6269304 0.34 ENST00000471204.1
ribosomal protein L22
chr14_-_88459503 0.34 ENST00000393568.4
ENST00000261304.2
galactosylceramidase
chr2_+_173420697 0.33 ENST00000282077.3
ENST00000392571.2
ENST00000410055.1
pyruvate dehydrogenase kinase, isozyme 1
chr3_+_52719936 0.33 ENST00000418458.1
ENST00000394799.2
guanine nucleotide binding protein-like 3 (nucleolar)
chr16_+_53164956 0.33 ENST00000563410.1
chromodomain helicase DNA binding protein 9
chr4_-_76649546 0.33 ENST00000508510.1
ENST00000509561.1
ENST00000499709.2
ENST00000511868.1
GTPase activating protein (SH3 domain) binding protein 2
chr14_-_64010046 0.32 ENST00000337537.3
protein phosphatase 2, regulatory subunit B', epsilon isoform
chr5_-_158636512 0.32 ENST00000424310.2
ring finger protein 145
chr19_-_49137790 0.32 ENST00000599385.1
D site of albumin promoter (albumin D-box) binding protein
chr1_-_220101944 0.32 ENST00000366926.3
ENST00000536992.1
solute carrier family 30, member 10
chr3_+_113666748 0.32 ENST00000330212.3
ENST00000498275.1
zinc finger, DHHC-type containing 23
chr7_-_95951334 0.32 ENST00000265631.5
solute carrier family 25 (aspartate/glutamate carrier), member 13
chr19_+_5720666 0.32 ENST00000381624.3
ENST00000381614.2
catsper channel auxiliary subunit delta
chr17_-_67323232 0.32 ENST00000592568.1
ENST00000392676.3
ATP-binding cassette, sub-family A (ABC1), member 5
chr22_+_35653445 0.32 ENST00000420166.1
ENST00000444518.2
ENST00000455359.1
ENST00000216106.5
HMG box domain containing 4
chr6_-_83775489 0.31 ENST00000369747.3
ubiquitin protein ligase E3D
chr2_-_98612379 0.31 ENST00000425805.2
transmembrane protein 131
chr12_-_123849374 0.31 ENST00000602398.1
ENST00000602750.1
strawberry notch homolog 1 (Drosophila)
chr17_-_8059638 0.31 ENST00000584202.1
ENST00000354903.5
ENST00000577253.1
period circadian clock 1
chr5_+_134094461 0.31 ENST00000452510.2
ENST00000354283.4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
chr6_+_108487245 0.31 ENST00000368986.4
nuclear receptor subfamily 2, group E, member 1
chr4_+_78079570 0.31 ENST00000509972.1
cyclin G2
chr10_+_98592009 0.31 ENST00000540664.1
ENST00000371103.3
ligand dependent nuclear receptor corepressor
chrX_+_100663243 0.31 ENST00000316594.5
heterogeneous nuclear ribonucleoprotein H2 (H')
chr15_+_38544476 0.30 ENST00000299084.4
sprouty-related, EVH1 domain containing 1
chr5_+_174905532 0.30 ENST00000502393.1
ENST00000506963.1
sideroflexin 1
chr14_-_53162215 0.30 ENST00000554251.1
ERO1-like (S. cerevisiae)
chr4_-_39529049 0.29 ENST00000501493.2
ENST00000509391.1
ENST00000507089.1
UDP-glucose 6-dehydrogenase
chr5_+_49962772 0.29 ENST00000281631.5
ENST00000513738.1
ENST00000503665.1
ENST00000514067.2
ENST00000503046.1
poly (ADP-ribose) polymerase family, member 8
chrX_-_34675391 0.29 ENST00000275954.3
transmembrane protein 47

Network of associatons between targets according to the STRING database.

First level regulatory network of HIF1A

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 5.1 GO:2000176 regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.5 1.6 GO:0034226 lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine import into cell(GO:1903410)
0.5 2.0 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.5 2.5 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.4 1.3 GO:0051780 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
0.3 1.6 GO:0043335 protein unfolding(GO:0043335)
0.3 1.5 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.3 1.8 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.3 0.8 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057)
0.3 0.8 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.2 2.0 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.2 1.0 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.2 1.2 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.2 1.7 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.2 0.6 GO:0035281 pre-miRNA export from nucleus(GO:0035281)
0.2 1.0 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.2 0.8 GO:0018277 protein deamination(GO:0018277)
0.2 0.7 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.2 1.2 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.2 0.5 GO:0044209 AMP salvage(GO:0044209)
0.1 0.7 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.1 0.7 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.1 0.4 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.1 0.9 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.1 0.5 GO:2000426 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) T-helper 1 cell activation(GO:0035711) negative regulation of apoptotic cell clearance(GO:2000426)
0.1 0.8 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 0.5 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.1 0.5 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.5 GO:0042360 vitamin E metabolic process(GO:0042360)
0.1 0.3 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.1 0.5 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.1 1.1 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.8 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.1 2.1 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 0.4 GO:0035425 autocrine signaling(GO:0035425)
0.1 0.5 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 0.3 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 1.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 0.2 GO:0046103 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
0.1 1.1 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.1 0.8 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.1 0.6 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.1 0.8 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.1 0.8 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.1 0.4 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.1 1.2 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.1 0.4 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.1 0.4 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 0.2 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
0.1 0.2 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.1 0.2 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.1 0.6 GO:0016198 axon choice point recognition(GO:0016198)
0.1 0.2 GO:0015670 carbon dioxide transport(GO:0015670)
0.1 0.4 GO:1990523 bone regeneration(GO:1990523)
0.1 0.5 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 1.0 GO:0045780 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.1 1.3 GO:0006004 fucose metabolic process(GO:0006004)
0.1 0.2 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.1 0.2 GO:0040040 thermosensory behavior(GO:0040040)
0.1 0.2 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.1 0.2 GO:0032917 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.0 0.4 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.0 0.7 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.0 0.5 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.0 0.2 GO:0090031 positive regulation of steroid hormone biosynthetic process(GO:0090031)
0.0 0.2 GO:1904693 negative regulation of mitotic cell cycle, embryonic(GO:0045976) midbrain morphogenesis(GO:1904693)
0.0 0.5 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.0 0.3 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.0 0.8 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.2 GO:0072318 clathrin coat disassembly(GO:0072318) negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.0 0.3 GO:0034214 protein hexamerization(GO:0034214) microtubule severing(GO:0051013)
0.0 0.2 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.0 0.2 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 0.2 GO:2000301 response to antineoplastic agent(GO:0097327) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 1.0 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.1 GO:0048817 negative regulation of hair follicle maturation(GO:0048817)
0.0 0.9 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.3 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.5 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.0 0.2 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.5 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.6 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.4 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.1 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0 0.1 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.0 0.9 GO:0006308 DNA catabolic process(GO:0006308)
0.0 3.2 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.3 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.4 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.2 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.3 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.4 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.4 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.0 0.5 GO:0048490 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.2 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 1.7 GO:0090307 mitotic spindle assembly(GO:0090307)
0.0 0.3 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 1.7 GO:0042795 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.1 GO:0021592 fourth ventricle development(GO:0021592)
0.0 0.9 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 0.3 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.3 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.0 0.1 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0 0.8 GO:0000075 cell cycle checkpoint(GO:0000075)
0.0 0.1 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.1 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
0.0 0.3 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.6 GO:0031440 regulation of mRNA 3'-end processing(GO:0031440)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0005960 glycine cleavage complex(GO:0005960)
0.2 0.6 GO:0042565 RNA nuclear export complex(GO:0042565)
0.2 0.9 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.2 0.7 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.6 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 0.9 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.1 1.5 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 0.5 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.1 1.2 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.1 1.0 GO:0044326 dendritic spine neck(GO:0044326)
0.1 1.7 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 0.7 GO:0032444 activin responsive factor complex(GO:0032444)
0.1 1.7 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 0.5 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 0.3 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 0.4 GO:0031417 NatC complex(GO:0031417)
0.1 0.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 1.0 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 1.3 GO:0097227 sperm annulus(GO:0097227)
0.1 1.0 GO:0032039 integrator complex(GO:0032039)
0.1 0.7 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 0.4 GO:0070876 SOSS complex(GO:0070876)
0.1 2.3 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.1 0.7 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 2.0 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 2.0 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.2 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.8 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.9 GO:0046930 pore complex(GO:0046930)
0.0 0.2 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.7 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 0.3 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.3 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.2 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.2 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 1.6 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.1 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.4 GO:0033270 paranodal junction(GO:0033010) paranode region of axon(GO:0033270)
0.0 1.6 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.9 GO:0090544 BAF-type complex(GO:0090544)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.1 GO:0097513 myosin II filament(GO:0097513)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 1.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.1 GO:0071547 piP-body(GO:0071547)
0.0 1.2 GO:0015030 Cajal body(GO:0015030)
0.0 0.2 GO:0032433 filopodium tip(GO:0032433)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.4 GO:0031527 filopodium membrane(GO:0031527)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.0 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.5 2.5 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.4 1.3 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
0.4 1.5 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.3 1.0 GO:0008859 exoribonuclease II activity(GO:0008859)
0.3 1.0 GO:0072510 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.3 1.6 GO:0005292 high-affinity basic amino acid transmembrane transporter activity(GO:0005287) high-affinity arginine transmembrane transporter activity(GO:0005289) high-affinity lysine transmembrane transporter activity(GO:0005292)
0.3 0.9 GO:0070123 transforming growth factor beta receptor activity, type III(GO:0070123)
0.2 0.6 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.2 1.3 GO:0070568 guanylyltransferase activity(GO:0070568)
0.2 1.7 GO:0043515 kinetochore binding(GO:0043515)
0.2 0.6 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.4 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 0.8 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.1 0.4 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.1 0.8 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 5.1 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 0.7 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 0.5 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 1.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 1.4 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.2 GO:0004807 triose-phosphate isomerase activity(GO:0004807)
0.1 0.8 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 0.3 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.8 GO:0055104 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.1 0.2 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.1 0.5 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.1 0.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.9 GO:0015288 porin activity(GO:0015288)
0.1 0.8 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 0.4 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.1 0.9 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.1 1.4 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 0.4 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 0.2 GO:0004145 diamine N-acetyltransferase activity(GO:0004145) polyamine binding(GO:0019808)
0.1 0.6 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.4 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.5 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 1.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 1.4 GO:0005521 lamin binding(GO:0005521)
0.0 0.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.7 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.7 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 2.7 GO:0019894 kinesin binding(GO:0019894)
0.0 0.8 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.2 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 1.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 1.6 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 1.0 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.9 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.1 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.0 0.5 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.3 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.4 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.7 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.9 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.2 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.7 GO:0004707 MAP kinase activity(GO:0004707)
0.0 1.4 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.2 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.2 GO:0015250 water channel activity(GO:0015250)
0.0 0.3 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.5 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.1 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.2 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.2 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 1.3 GO:0019003 GDP binding(GO:0019003)
0.0 0.4 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.3 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.5 GO:0019206 nucleoside kinase activity(GO:0019206)
0.0 0.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.5 GO:0031489 myosin V binding(GO:0031489)
0.0 0.6 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.3 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.4 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 1.7 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0046527 glucosyltransferase activity(GO:0046527)
0.0 0.2 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.8 GO:0044390 ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0 0.8 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 4.2 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.2 PID ARF 3PATHWAY Arf1 pathway
0.0 0.6 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.9 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.0 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.8 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 1.2 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.1 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.1 PID ENDOTHELIN PATHWAY Endothelins
0.0 1.6 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.5 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.8 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 1.0 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.7 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.3 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.8 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.1 0.8 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 1.2 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 2.3 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.7 REACTOME KINESINS Genes involved in Kinesins
0.0 2.7 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.2 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.5 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.7 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.0 0.9 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.5 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.5 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.9 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.8 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.5 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.7 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 1.5 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 1.3 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.5 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.5 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.8 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.4 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.5 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 1.1 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 2.3 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 2.4 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.3 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.0 0.7 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 1.0 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.9 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0 0.5 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.7 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.2 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters