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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for GUAAACA
Z-value: 1.96
Motif logo
miRNA associated with seed GUAAACA
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr3_-_182698381 Show fit | 1.24 |
ENST00000292782.4
|
DCN1, defective in cullin neddylation 1, domain containing 1 |
|
| chr15_-_34502278 Show fit | 1.18 |
ENST00000559515.1
ENST00000256544.3 ENST00000560108.1 ENST00000559462.1 |
katanin p80 subunit B-like 1 |
|
| chr1_-_197169672 Show fit | 1.16 |
ENST00000367405.4
|
zinc finger and BTB domain containing 41 |
|
| chr8_+_48920960 Show fit | 1.11 |
ENST00000523111.2
ENST00000523432.1 ENST00000521346.1 ENST00000517630.1 |
ubiquitin-conjugating enzyme E2 variant 2 |
|
| chr18_-_19180681 Show fit | 1.10 |
ENST00000269214.5
|
establishment of sister chromatid cohesion N-acetyltransferase 1 |
|
| chr18_+_52495426 Show fit | 1.08 |
ENST00000262094.5
|
RAB27B, member RAS oncogene family |
|
| chr7_+_87505544 Show fit | 1.03 |
ENST00000265728.1
|
DBF4 homolog (S. cerevisiae) |
|
| chr5_-_59189545 Show fit | 1.03 |
ENST00000340635.6
|
phosphodiesterase 4D, cAMP-specific |
|
| chr2_-_61765315 Show fit | 0.98 |
ENST00000406957.1
ENST00000401558.2 |
exportin 1 (CRM1 homolog, yeast) |
|
| chr4_+_174089904 Show fit | 0.95 |
ENST00000265000.4
|
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7) |
Network of associatons between targets according to the STRING database.
First level regulatory network of GUAAACA
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.0 | GO:0070911 | global genome nucleotide-excision repair(GO:0070911) |
| 0.1 | 1.7 | GO:0045116 | protein neddylation(GO:0045116) |
| 0.0 | 1.5 | GO:0016266 | O-glycan processing(GO:0016266) |
| 0.0 | 1.3 | GO:0006270 | DNA replication initiation(GO:0006270) |
| 0.1 | 1.2 | GO:0090168 | Golgi reassembly(GO:0090168) |
| 0.0 | 1.2 | GO:0033173 | calcineurin-NFAT signaling cascade(GO:0033173) |
| 0.2 | 1.1 | GO:0034421 | post-translational protein acetylation(GO:0034421) |
| 0.1 | 1.1 | GO:0018103 | protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406) |
| 0.0 | 1.1 | GO:0006020 | inositol metabolic process(GO:0006020) |
| 0.0 | 1.1 | GO:0071985 | multivesicular body sorting pathway(GO:0071985) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.9 | GO:0042589 | zymogen granule membrane(GO:0042589) |
| 0.0 | 1.9 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.1 | 1.2 | GO:0071203 | WASH complex(GO:0071203) |
| 0.4 | 1.1 | GO:0031372 | UBC13-MMS2 complex(GO:0031372) |
| 0.0 | 1.1 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.0 | 1.1 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.1 | 1.0 | GO:0005642 | annulate lamellae(GO:0005642) |
| 0.0 | 0.9 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.0 | 0.9 | GO:0071004 | U2-type prespliceosome(GO:0071004) |
| 0.0 | 0.9 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.6 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 0.0 | 1.7 | GO:0019003 | GDP binding(GO:0019003) |
| 0.0 | 1.6 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.1 | 1.5 | GO:0031698 | beta-2 adrenergic receptor binding(GO:0031698) |
| 0.0 | 1.2 | GO:0000030 | mannosyltransferase activity(GO:0000030) |
| 0.0 | 1.2 | GO:0061733 | peptide-lysine-N-acetyltransferase activity(GO:0061733) |
| 0.1 | 1.0 | GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) |
| 0.1 | 1.0 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
| 0.0 | 1.0 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.0 | 0.9 | GO:0097602 | cullin family protein binding(GO:0097602) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.2 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.0 | 1.8 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.1 | 1.7 | PID THROMBIN PAR4 PATHWAY | PAR4-mediated thrombin signaling events |
| 0.1 | 1.1 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 0.0 | 1.1 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.0 | 0.9 | ST WNT CA2 CYCLIC GMP PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
| 0.0 | 0.9 | PID MAPK TRK PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
| 0.0 | 0.9 | PID HEDGEHOG GLI PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.0 | 0.7 | PID IL12 STAT4 PATHWAY | IL12 signaling mediated by STAT4 |
| 0.0 | 0.6 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.8 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
| 0.0 | 1.4 | REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR | Genes involved in Thromboxane signalling through TP receptor |
| 0.0 | 1.3 | REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.1 | 1.2 | REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA | Genes involved in Activation of Chaperones by ATF6-alpha |
| 0.0 | 1.2 | REACTOME O LINKED GLYCOSYLATION OF MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.0 | 1.1 | REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
| 0.0 | 1.0 | REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
| 0.0 | 1.0 | REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX | Genes involved in Activation of the pre-replicative complex |
| 0.0 | 1.0 | REACTOME RAP1 SIGNALLING | Genes involved in Rap1 signalling |
| 0.1 | 0.8 | REACTOME ACYL CHAIN REMODELLING OF PG | Genes involved in Acyl chain remodelling of PG |