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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for GGCUCAG
Z-value: 1.34
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miRNA associated with seed GGCUCAG
| Name | miRBASE accession |
|---|---|
|
hsa-miR-24-3p
|
MIMAT0000080 |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr7_-_74867509 Show fit | 0.81 |
ENST00000426327.3
|
GATS protein-like 2 |
|
| chr11_+_61447845 Show fit | 0.69 |
ENST00000257215.5
|
diacylglycerol lipase, alpha |
|
| chr16_+_67927147 Show fit | 0.67 |
ENST00000291041.5
|
protein serine kinase H1 |
|
| chr5_+_149887672 Show fit | 0.66 |
ENST00000261797.6
|
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 |
|
| chr17_+_19281034 Show fit | 0.66 |
ENST00000308406.5
ENST00000299612.7 |
mitogen-activated protein kinase 7 |
|
| chr12_-_56652111 Show fit | 0.62 |
ENST00000267116.7
|
ankyrin repeat domain 52 |
|
| chr22_+_42196666 Show fit | 0.58 |
ENST00000402061.3
ENST00000255784.5 |
coiled-coil domain containing 134 |
|
| chr17_-_79885576 Show fit | 0.55 |
ENST00000574686.1
ENST00000357736.4 |
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
|
| chr20_+_1875110 Show fit | 0.55 |
ENST00000400068.3
|
signal-regulatory protein alpha |
|
| chr3_+_150126101 Show fit | 0.55 |
ENST00000361875.3
ENST00000361136.2 |
TSC22 domain family, member 2 |
Network of associatons between targets according to the STRING database.
First level regulatory network of GGCUCAG
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 0.7 | GO:0070376 | regulation of ERK5 cascade(GO:0070376) negative regulation of ERK5 cascade(GO:0070377) |
| 0.2 | 0.7 | GO:0046340 | diacylglycerol catabolic process(GO:0046340) |
| 0.1 | 0.7 | GO:0006477 | protein sulfation(GO:0006477) |
| 0.0 | 0.7 | GO:0006509 | membrane protein ectodomain proteolysis(GO:0006509) |
| 0.1 | 0.6 | GO:0070309 | lens fiber cell morphogenesis(GO:0070309) |
| 0.2 | 0.5 | GO:0006419 | alanyl-tRNA aminoacylation(GO:0006419) |
| 0.1 | 0.5 | GO:0090625 | mRNA cleavage involved in gene silencing by siRNA(GO:0090625) |
| 0.1 | 0.5 | GO:0072675 | multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675) |
| 0.1 | 0.5 | GO:1990834 | response to odorant(GO:1990834) |
| 0.0 | 0.5 | GO:0060385 | axonogenesis involved in innervation(GO:0060385) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.7 | GO:0043196 | varicosity(GO:0043196) |
| 0.0 | 0.5 | GO:0044352 | pinosome(GO:0044352) macropinosome(GO:0044354) |
| 0.0 | 0.5 | GO:0043240 | Fanconi anaemia nuclear complex(GO:0043240) |
| 0.0 | 0.5 | GO:0035068 | micro-ribonucleoprotein complex(GO:0035068) |
| 0.0 | 0.5 | GO:0017119 | Golgi transport complex(GO:0017119) |
| 0.0 | 0.4 | GO:0001673 | male germ cell nucleus(GO:0001673) |
| 0.0 | 0.4 | GO:0097443 | sorting endosome(GO:0097443) |
| 0.0 | 0.4 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
| 0.0 | 0.4 | GO:0010369 | chromocenter(GO:0010369) |
| 0.1 | 0.3 | GO:0044393 | microspike(GO:0044393) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.8 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
| 0.1 | 0.7 | GO:0050119 | N-acetylglucosamine deacetylase activity(GO:0050119) |
| 0.0 | 0.7 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
| 0.0 | 0.7 | GO:0004707 | MAP kinase activity(GO:0004707) |
| 0.2 | 0.5 | GO:0004813 | alanine-tRNA ligase activity(GO:0004813) |
| 0.0 | 0.5 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
| 0.0 | 0.5 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
| 0.0 | 0.5 | GO:0035198 | miRNA binding(GO:0035198) |
| 0.0 | 0.5 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 0.0 | 0.5 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.9 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.0 | 0.8 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 0.0 | 0.8 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.0 | 0.7 | ST GA12 PATHWAY | G alpha 12 Pathway |
| 0.0 | 0.7 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.0 | 0.7 | PID IL3 PATHWAY | IL3-mediated signaling events |
| 0.0 | 0.4 | PID S1P S1P1 PATHWAY | S1P1 pathway |
| 0.0 | 0.3 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
| 0.0 | 0.2 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.0 | REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
| 0.0 | 0.7 | REACTOME ERKS ARE INACTIVATED | Genes involved in ERKs are inactivated |
| 0.0 | 0.7 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.0 | 0.7 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.0 | 0.6 | REACTOME HS GAG BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.0 | 0.6 | REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS | Genes involved in Signal regulatory protein (SIRP) family interactions |
| 0.0 | 0.6 | REACTOME EFFECTS OF PIP2 HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
| 0.0 | 0.5 | REACTOME MITOCHONDRIAL TRNA AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
| 0.0 | 0.5 | REACTOME FANCONI ANEMIA PATHWAY | Genes involved in Fanconi Anemia pathway |
| 0.0 | 0.5 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |