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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for FOXQ1

Z-value: 1.30

Motif logo

Transcription factors associated with FOXQ1

Gene Symbol Gene ID Gene Info
ENSG00000164379.4 forkhead box Q1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXQ1hg19_v2_chr6_+_1312675_1312701-0.029.7e-01Click!

Activity profile of FOXQ1 motif

Sorted Z-values of FOXQ1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_27998689 4.76 ENST00000339145.4
ENST00000362020.4
ENST00000361157.6
interferon, alpha-inducible protein 6
chr11_-_615942 2.05 ENST00000397562.3
ENST00000330243.5
ENST00000397570.1
ENST00000397574.2
interferon regulatory factor 7
chr11_-_615570 1.92 ENST00000525445.1
ENST00000348655.6
ENST00000397566.1
interferon regulatory factor 7
chr2_-_37374876 1.22 ENST00000405334.1
eukaryotic translation initiation factor 2-alpha kinase 2
chr4_-_111120334 1.17 ENST00000503885.1
ELOVL fatty acid elongase 6
chr3_+_136649311 1.04 ENST00000469404.1
ENST00000467911.1
NCK adaptor protein 1
chr15_+_63188009 1.01 ENST00000557900.1
RP11-1069G10.2
chr3_+_164924716 0.89 ENST00000470138.1
ENST00000498616.1
RP11-85M11.2
chrM_+_10464 0.88 ENST00000361335.1
mitochondrially encoded NADH dehydrogenase 4L
chr7_-_81635106 0.85 ENST00000443883.1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr15_+_49715449 0.85 ENST00000560979.1
fibroblast growth factor 7
chr6_-_32083106 0.84 ENST00000442721.1
tenascin XB
chr17_+_45771420 0.82 ENST00000578982.1
TBK1 binding protein 1
chr4_-_111120132 0.82 ENST00000506625.1
ELOVL fatty acid elongase 6
chr5_+_94982435 0.80 ENST00000511684.1
ENST00000380005.4
Rieske (Fe-S) domain containing
chr10_-_36813162 0.79 ENST00000440465.1
nicotinamide phosphoribosyltransferase-like
chr2_-_188419078 0.73 ENST00000437725.1
ENST00000409676.1
ENST00000339091.4
ENST00000420747.1
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr2_+_173955327 0.72 ENST00000422149.1
Mitogen-activated protein kinase kinase kinase MLT
chr4_+_86749045 0.71 ENST00000514229.1
Rho GTPase activating protein 24
chr8_+_142264664 0.70 ENST00000518520.1
Uncharacterized protein
chr2_-_61389240 0.70 ENST00000606876.1
RP11-493E12.1
chr17_-_39341594 0.69 ENST00000398472.1
keratin associated protein 4-1
chr14_+_51026926 0.68 ENST00000557735.1
atlastin GTPase 1
chr21_-_16254231 0.67 ENST00000412426.1
ENST00000418954.1
AF127936.7
chr17_+_68164752 0.63 ENST00000535240.1
potassium inwardly-rectifying channel, subfamily J, member 2
chr4_-_159094194 0.63 ENST00000592057.1
ENST00000585682.1
ENST00000393807.5
family with sequence similarity 198, member B
chr3_-_148939598 0.62 ENST00000455472.3
ceruloplasmin (ferroxidase)
chr7_-_64023441 0.61 ENST00000309683.6
zinc finger protein 680
chr21_-_33975547 0.61 ENST00000431599.1
chromosome 21 open reading frame 59
chr17_+_70036164 0.60 ENST00000602013.1
Uncharacterized protein
chr12_-_76478386 0.59 ENST00000535020.2
nucleosome assembly protein 1-like 1
chr3_+_172468749 0.59 ENST00000366254.2
ENST00000415665.1
ENST00000438041.1
epithelial cell transforming sequence 2 oncogene
chr1_+_92632542 0.58 ENST00000409154.4
ENST00000370378.4
KIAA1107
chr7_-_124569991 0.57 ENST00000446993.1
ENST00000357628.3
ENST00000393329.1
protection of telomeres 1
chr19_+_44455368 0.57 ENST00000591168.1
ENST00000587682.1
ENST00000251269.5
zinc finger protein 221
chr2_-_188419200 0.57 ENST00000233156.3
ENST00000426055.1
ENST00000453013.1
ENST00000417013.1
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr10_-_94301107 0.55 ENST00000436178.1
insulin-degrading enzyme
chr5_-_24645078 0.54 ENST00000264463.4
cadherin 10, type 2 (T2-cadherin)
chrM_+_10758 0.54 ENST00000361381.2
mitochondrially encoded NADH dehydrogenase 4
chr1_+_70820451 0.53 ENST00000361764.4
ENST00000359875.5
ENST00000370940.5
ENST00000531950.1
ENST00000432224.1
HERV-H LTR-associating 3
chr1_+_151739131 0.53 ENST00000400999.1
ornithine decarboxylase antizyme 3
chr1_+_95616933 0.52 ENST00000604203.1
TMEM56-RWDD3 readthrough
chr4_+_17578815 0.52 ENST00000226299.4
leucine aminopeptidase 3
chr3_+_98699880 0.51 ENST00000473756.1
long intergenic non-protein coding RNA 973
chr1_+_215747118 0.51 ENST00000448333.1
potassium channel tetramerization domain containing 3
chrM_+_5824 0.50 ENST00000361624.2
mitochondrially encoded cytochrome c oxidase I
chr14_+_51026844 0.50 ENST00000554886.1
atlastin GTPase 1
chr8_+_94767072 0.50 ENST00000452276.1
ENST00000453321.3
ENST00000498673.1
ENST00000518319.1
transmembrane protein 67
chr12_-_8803128 0.49 ENST00000543467.1
microfibrillar associated protein 5
chr6_+_123038689 0.49 ENST00000354275.2
ENST00000368446.1
protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr4_+_155484155 0.49 ENST00000509493.1
fibrinogen beta chain
chr16_-_90096309 0.49 ENST00000408886.2
chromosome 16 open reading frame 3
chr4_-_103266626 0.48 ENST00000356736.4
solute carrier family 39 (zinc transporter), member 8
chr9_-_3469181 0.48 ENST00000366116.2
Uncharacterized protein
chr7_+_7196565 0.48 ENST00000429911.1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr12_-_76461249 0.48 ENST00000551524.1
nucleosome assembly protein 1-like 1
chr4_+_79567362 0.47 ENST00000512322.1
long intergenic non-protein coding RNA 1094
chr19_-_48823332 0.47 ENST00000315396.7
coiled-coil domain containing 114
chr1_-_54405773 0.46 ENST00000371376.1
heat shock protein family B (small), member 11
chr14_-_35591156 0.46 ENST00000554361.1
protein phosphatase 2, regulatory subunit B'', gamma
chr3_-_96337000 0.46 ENST00000600213.2
MT-RNR2-like 12 (pseudogene)
chr8_-_17752912 0.45 ENST00000398054.1
ENST00000381840.2
fibrinogen-like 1
chr3_+_69811858 0.45 ENST00000433517.1
microphthalmia-associated transcription factor
chr4_-_70626430 0.45 ENST00000310613.3
sulfotransferase family, cytosolic, 1B, member 1
chr15_+_57891609 0.45 ENST00000569089.1
myocardial zonula adherens protein
chr1_+_240177627 0.45 ENST00000447095.1
formin 2
chr12_-_76478417 0.45 ENST00000552342.1
nucleosome assembly protein 1-like 1
chr8_+_110551925 0.45 ENST00000395785.2
estrogen receptor binding site associated, antigen, 9
chr11_+_34654011 0.43 ENST00000531794.1
ets homologous factor
chr9_-_123812542 0.43 ENST00000223642.1
complement component 5
chr4_+_95174445 0.43 ENST00000509418.1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr4_-_111119804 0.43 ENST00000394607.3
ENST00000302274.3
ELOVL fatty acid elongase 6
chr20_+_12989596 0.42 ENST00000434210.1
ENST00000399002.2
serine palmitoyltransferase, long chain base subunit 3
chr3_+_157154578 0.42 ENST00000295927.3
pentraxin 3, long
chr2_-_150444116 0.42 ENST00000428879.1
ENST00000422782.2
methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
chr4_-_74853897 0.41 ENST00000296028.3
pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
chr14_+_52456327 0.41 ENST00000556760.1
chromosome 14 open reading frame 166
chr12_-_102133191 0.41 ENST00000392924.1
ENST00000266743.2
ENST00000392927.3
synaptonemal complex protein 3
chr6_-_133084580 0.40 ENST00000525270.1
ENST00000530536.1
ENST00000524919.1
vanin 2
chr14_+_56078695 0.40 ENST00000416613.1
kinectin 1 (kinesin receptor)
chr18_+_61445007 0.40 ENST00000447428.1
ENST00000546027.1
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr3_-_178976996 0.40 ENST00000485523.1
potassium large conductance calcium-activated channel, subfamily M beta member 3
chrX_+_49020882 0.40 ENST00000454342.1
MAGI family member, X-linked
chr10_+_94594351 0.39 ENST00000371552.4
exocyst complex component 6
chr14_-_23288930 0.39 ENST00000554517.1
ENST00000285850.7
ENST00000397529.2
ENST00000555702.1
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr5_+_65440032 0.39 ENST00000334121.6
splicing regulatory glutamine/lysine-rich protein 1
chr5_+_64920543 0.38 ENST00000399438.3
ENST00000510585.2
trafficking protein particle complex 13
CDNA FLJ26957 fis, clone SLV00486; Uncharacterized protein
chr1_+_16083098 0.38 ENST00000496928.2
ENST00000508310.1
filamin binding LIM protein 1
chr12_-_76462713 0.38 ENST00000552056.1
nucleosome assembly protein 1-like 1
chr6_+_151358048 0.38 ENST00000450635.1
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr12_-_76478446 0.38 ENST00000393263.3
ENST00000548044.1
ENST00000547704.1
ENST00000431879.3
ENST00000549596.1
ENST00000550934.1
ENST00000551600.1
ENST00000547479.1
ENST00000547773.1
ENST00000544816.1
ENST00000542344.1
ENST00000548273.1
nucleosome assembly protein 1-like 1
chr2_-_150444300 0.38 ENST00000303319.5
methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
chr3_-_145940214 0.37 ENST00000481701.1
phospholipid scramblase 4
chr9_+_79792410 0.37 ENST00000357409.5
vacuolar protein sorting 13 homolog A (S. cerevisiae)
chr6_-_114194483 0.37 ENST00000434296.2
RP1-249H1.4
chr15_-_59041768 0.37 ENST00000402627.1
ENST00000396140.2
ENST00000559053.1
ENST00000561288.1
ADAM metallopeptidase domain 10
chr6_+_12008986 0.36 ENST00000491710.1
human immunodeficiency virus type I enhancer binding protein 1
chr8_+_109455845 0.36 ENST00000220853.3
ER membrane protein complex subunit 2
chr3_+_190333097 0.36 ENST00000412080.1
interleukin 1 receptor accessory protein
chr9_+_67977438 0.36 ENST00000456982.1
Protein LOC644249
chr9_+_82267508 0.35 ENST00000490347.1
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr18_-_57027194 0.35 ENST00000251047.5
lectin, mannose-binding, 1
chr19_+_35899569 0.35 ENST00000600405.1
AC002511.1
chr7_+_135611542 0.35 ENST00000416501.1
AC015987.2
chr3_+_184529948 0.35 ENST00000436792.2
ENST00000446204.2
ENST00000422105.1
vacuolar protein sorting 8 homolog (S. cerevisiae)
chr2_-_225434538 0.34 ENST00000409096.1
cullin 3
chr2_+_170440844 0.34 ENST00000260970.3
ENST00000433207.1
ENST00000409714.3
ENST00000462903.1
peptidylprolyl isomerase G (cyclophilin G)
chr8_-_103884640 0.34 ENST00000520402.1
antizyme inhibitor 1
chr8_+_110552046 0.34 ENST00000529931.1
estrogen receptor binding site associated, antigen, 9
chr6_+_21666633 0.34 ENST00000606851.1
cancer susceptibility candidate 15 (non-protein coding)
chr3_+_184529929 0.33 ENST00000287546.4
ENST00000437079.3
vacuolar protein sorting 8 homolog (S. cerevisiae)
chr9_-_119162885 0.33 ENST00000445861.2
PAPPA antisense RNA 1
chr5_-_159846066 0.33 ENST00000519349.1
ENST00000520664.1
SLU7 splicing factor homolog (S. cerevisiae)
chr11_-_14521379 0.33 ENST00000249923.3
ENST00000529866.1
ENST00000439561.2
ENST00000534771.1
coatomer protein complex, subunit beta 1
chr8_-_30013748 0.32 ENST00000607315.1
RP11-51J9.5
chr5_+_64920826 0.32 ENST00000438419.2
ENST00000231526.4
ENST00000505553.1
ENST00000545191.1
trafficking protein particle complex 13
chr10_-_52008313 0.32 ENST00000329428.6
ENST00000395526.4
ENST00000447815.1
N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
chr4_+_155484103 0.32 ENST00000302068.4
fibrinogen beta chain
chr1_+_84629976 0.32 ENST00000446538.1
ENST00000370684.1
ENST00000436133.1
protein kinase, cAMP-dependent, catalytic, beta
chr2_+_143635222 0.32 ENST00000375773.2
ENST00000409512.1
ENST00000410015.2
kynureninase
chr4_-_147443043 0.32 ENST00000394059.4
ENST00000502607.1
ENST00000335472.7
ENST00000432059.2
ENST00000394062.3
solute carrier family 10, member 7
chr8_-_55014018 0.32 ENST00000521352.1
lysophospholipase I
chr3_+_122513642 0.32 ENST00000261038.5
disrupted in renal carcinoma 2
chr5_-_41510725 0.32 ENST00000328457.3
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr14_+_56127989 0.31 ENST00000555573.1
kinectin 1 (kinesin receptor)
chr17_+_9745786 0.31 ENST00000304773.5
glucagon-like peptide 2 receptor
chr12_-_51418549 0.31 ENST00000548150.1
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chr2_+_105050794 0.31 ENST00000429464.1
ENST00000414442.1
ENST00000447380.1
long intergenic non-protein coding RNA 1102
chr15_+_80351977 0.31 ENST00000559157.1
ENST00000561012.1
ENST00000564367.1
ENST00000558494.1
zinc finger, AN1-type domain 6
chr11_+_6947647 0.31 ENST00000278319.5
zinc finger protein 215
chr8_-_82644562 0.31 ENST00000520604.1
ENST00000521742.1
ENST00000520635.1
zinc finger, AN1-type domain 1
chr3_-_57233966 0.31 ENST00000473921.1
ENST00000295934.3
HESX homeobox 1
chr1_+_63989004 0.31 ENST00000371088.4
EF-hand calcium binding domain 7
chr8_+_94767109 0.31 ENST00000409623.3
ENST00000453906.1
ENST00000521517.1
transmembrane protein 67
chr1_+_120839412 0.30 ENST00000355228.4
family with sequence similarity 72, member B
chr14_+_96722539 0.30 ENST00000553356.1
bradykinin receptor B1
chr2_+_190306159 0.30 ENST00000314761.4
WD repeat domain 75
chr11_-_107328527 0.30 ENST00000282251.5
ENST00000433523.1
CWF19-like 2, cell cycle control (S. pombe)
chr3_-_156840776 0.30 ENST00000471357.1
long intergenic non-protein coding RNA 880
chr1_+_172422026 0.30 ENST00000367725.4
chromosome 1 open reading frame 105
chr12_-_10588539 0.29 ENST00000381902.2
ENST00000381901.1
ENST00000539033.1
killer cell lectin-like receptor subfamily C, member 2
Uncharacterized protein
chr15_-_56757329 0.29 ENST00000260453.3
meiosis-specific nuclear structural 1
chr9_-_15472730 0.29 ENST00000481862.1
PC4 and SFRS1 interacting protein 1
chr14_+_56127960 0.29 ENST00000553624.1
kinectin 1 (kinesin receptor)
chr6_+_88182643 0.29 ENST00000369556.3
ENST00000544441.1
ENST00000369552.4
ENST00000369557.5
solute carrier family 35 (CMP-sialic acid transporter), member A1
chr2_+_201450591 0.29 ENST00000374700.2
aldehyde oxidase 1
chr10_-_21661870 0.29 ENST00000433460.1
RP11-275N1.1
chr2_+_143635067 0.29 ENST00000264170.4
kynureninase
chr8_+_125486939 0.28 ENST00000303545.3
ring finger protein 139
chr4_-_147442817 0.28 ENST00000507030.1
solute carrier family 10, member 7
chr19_+_11466062 0.28 ENST00000251473.5
ENST00000591329.1
ENST00000586380.1
Lipid phosphate phosphatase-related protein type 2
chrX_-_71525742 0.28 ENST00000450875.1
ENST00000417400.1
ENST00000431381.1
ENST00000445983.1
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
chr6_+_136172820 0.28 ENST00000308191.6
phosphodiesterase 7B
chrX_+_9880412 0.28 ENST00000418909.2
shroom family member 2
chr5_+_136070614 0.28 ENST00000502421.1
CTB-1I21.1
chr5_+_93954039 0.28 ENST00000265140.5
ankyrin repeat domain 32
chr18_-_52626622 0.28 ENST00000591504.1
coiled-coil domain containing 68
chr4_-_185694872 0.28 ENST00000505492.1
acyl-CoA synthetase long-chain family member 1
chr14_+_67831576 0.28 ENST00000555876.1
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr14_+_73563735 0.28 ENST00000532192.1
RNA binding motif protein 25
chr17_-_29233769 0.27 ENST00000581216.1
transcription elongation factor, mitochondrial
chr1_+_104159999 0.27 ENST00000414303.2
ENST00000423678.1
amylase, alpha 2A (pancreatic)
chr1_-_182360498 0.27 ENST00000417584.2
glutamate-ammonia ligase
chr4_+_95916947 0.26 ENST00000506363.1
bone morphogenetic protein receptor, type IB
chrX_-_99891796 0.26 ENST00000373020.4
tetraspanin 6
chr3_-_19975665 0.26 ENST00000295824.9
ENST00000389256.4
EF-hand domain family, member B
chr4_+_26578293 0.26 ENST00000512840.1
TBC1 domain family, member 19
chr8_-_95487331 0.25 ENST00000336148.5
RAD54 homolog B (S. cerevisiae)
chr1_+_24645807 0.25 ENST00000361548.4
grainyhead-like 3 (Drosophila)
chr6_-_28554977 0.25 ENST00000452236.2
SCAN domain containing 3
chr12_+_28410128 0.25 ENST00000381259.1
ENST00000381256.1
coiled-coil domain containing 91
chrM_+_10053 0.25 ENST00000361227.2
mitochondrially encoded NADH dehydrogenase 3
chr2_+_183582774 0.25 ENST00000537515.1
DnaJ (Hsp40) homolog, subfamily C, member 10
chr14_+_51026743 0.25 ENST00000358385.6
ENST00000357032.3
ENST00000354525.4
atlastin GTPase 1
chr1_+_24645865 0.25 ENST00000342072.4
grainyhead-like 3 (Drosophila)
chr5_-_111091948 0.25 ENST00000447165.2
neuronal regeneration related protein
chr10_-_73848086 0.24 ENST00000536168.1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr15_-_55489097 0.24 ENST00000260443.4
ribosomal L24 domain containing 1
chr2_-_55459294 0.24 ENST00000407122.1
ENST00000406437.2
clathrin heavy chain linker domain containing 1
chr5_+_102201722 0.24 ENST00000274392.9
ENST00000455264.2
peptidylglycine alpha-amidating monooxygenase
chr4_+_86396321 0.24 ENST00000503995.1
Rho GTPase activating protein 24
chr17_-_38574169 0.24 ENST00000423485.1
topoisomerase (DNA) II alpha 170kDa
chr5_+_118690466 0.24 ENST00000503646.1
tumor necrosis factor, alpha-induced protein 8
chr12_+_19928380 0.24 ENST00000535764.1
RP11-405A12.2
chr5_-_159846399 0.24 ENST00000297151.4
SLU7 splicing factor homolog (S. cerevisiae)
chr10_+_35484793 0.23 ENST00000488741.1
ENST00000474931.1
ENST00000468236.1
ENST00000344351.5
ENST00000490511.1
cAMP responsive element modulator
chr7_+_95115210 0.23 ENST00000428113.1
ENST00000325885.5
ankyrin repeat and SOCS box containing 4
chr5_+_140625147 0.23 ENST00000231173.3
protocadherin beta 15
chr1_+_24646002 0.23 ENST00000356046.2
grainyhead-like 3 (Drosophila)
chr13_+_33160553 0.23 ENST00000315596.10
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr14_-_34420259 0.23 ENST00000250457.3
ENST00000547327.2
egl-9 family hypoxia-inducible factor 3
chr1_-_115259337 0.22 ENST00000369535.4
neuroblastoma RAS viral (v-ras) oncogene homolog
chr2_+_170440902 0.22 ENST00000448752.2
ENST00000418888.1
ENST00000414307.1
peptidylprolyl isomerase G (cyclophilin G)
chr15_+_89182178 0.22 ENST00000559876.1
interferon stimulated exonuclease gene 20kDa
chr7_-_140624499 0.22 ENST00000288602.6
v-raf murine sarcoma viral oncogene homolog B
chr12_+_72233487 0.22 ENST00000482439.2
ENST00000550746.1
ENST00000491063.1
ENST00000319106.8
ENST00000485960.2
ENST00000393309.3
TBC1 domain family, member 15
chr15_+_89182156 0.22 ENST00000379224.5
interferon stimulated exonuclease gene 20kDa
chr10_+_13652047 0.22 ENST00000601460.1
Uncharacterized protein
chr16_-_25122735 0.22 ENST00000563176.1
RP11-449H11.1
chr16_-_71323617 0.22 ENST00000563876.1
cap methyltransferase 2

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXQ1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 4.0 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.4 4.8 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.3 1.0 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.2 2.4 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.2 0.6 GO:0060382 regulation of DNA strand elongation(GO:0060382)
0.2 1.3 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.2 1.0 GO:0060437 lung growth(GO:0060437)
0.2 0.6 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.1 0.4 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.1 0.6 GO:1901143 insulin catabolic process(GO:1901143)
0.1 0.4 GO:0008057 eye pigment granule organization(GO:0008057)
0.1 0.4 GO:0036451 cap mRNA methylation(GO:0036451)
0.1 0.6 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.1 1.2 GO:0051834 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1 0.5 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 0.5 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.1 0.5 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.1 0.8 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.1 0.5 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.1 0.5 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.1 0.5 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.1 0.4 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.1 0.3 GO:1902267 polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267)
0.1 0.4 GO:0001878 response to yeast(GO:0001878)
0.1 0.4 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.1 0.4 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.1 0.8 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.4 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.1 0.3 GO:0046110 xanthine metabolic process(GO:0046110)
0.1 0.2 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.1 0.3 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.1 0.3 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.1 0.5 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.1 0.4 GO:0002001 renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure(GO:0001999) renin secretion into blood stream(GO:0002001)
0.1 0.4 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
0.1 0.7 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.1 0.5 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 0.3 GO:0044245 polysaccharide digestion(GO:0044245)
0.1 0.2 GO:0002188 translation reinitiation(GO:0002188)
0.1 0.4 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.1 0.6 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.1 0.2 GO:0006433 glutamyl-tRNA aminoacylation(GO:0006424) prolyl-tRNA aminoacylation(GO:0006433)
0.0 0.3 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.2 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.0 0.5 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
0.0 0.5 GO:0097338 response to clozapine(GO:0097338)
0.0 0.2 GO:0006726 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0 0.2 GO:0032207 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.0 0.2 GO:0018032 protein amidation(GO:0018032)
0.0 0.2 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.4 GO:0000821 regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
0.0 0.3 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.2 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.2 GO:0002005 angiotensin catabolic process in blood(GO:0002005)
0.0 0.2 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.0 0.3 GO:0071105 response to interleukin-9(GO:0071104) response to interleukin-11(GO:0071105)
0.0 0.5 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.0 0.8 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.1 GO:0036071 N-glycan fucosylation(GO:0036071)
0.0 0.2 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.5 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.3 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.3 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0 0.6 GO:0010826 negative regulation of centrosome duplication(GO:0010826)
0.0 0.8 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.2 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.7 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 0.2 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.0 0.2 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.4 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.6 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.4 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.2 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.2 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.0 0.6 GO:0006825 copper ion transport(GO:0006825)
0.0 0.2 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.5 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.0 0.6 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.2 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.1 GO:0010157 response to chlorate(GO:0010157)
0.0 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.2 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0 0.4 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.3 GO:0034201 response to oleic acid(GO:0034201)
0.0 0.3 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.1 GO:0060529 ectoderm and mesoderm interaction(GO:0007499) squamous basal epithelial stem cell differentiation involved in prostate gland acinus development(GO:0060529)
0.0 0.1 GO:1990637 response to prolactin(GO:1990637)
0.0 0.1 GO:0070340 detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.0 0.1 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.2 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.0 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0 0.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.4 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0006203 dGTP catabolic process(GO:0006203)
0.0 0.4 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.4 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.3 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.0 0.2 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.1 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.5 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.1 GO:1904977 lymphatic endothelial cell migration(GO:1904977)
0.0 0.3 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 1.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.3 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.5 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.1 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.1 GO:0042126 nitrate metabolic process(GO:0042126)
0.0 0.5 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.0 0.2 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.0 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.2 GO:1902365 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.0 0.1 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
0.0 0.0 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.5 GO:0072662 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.2 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 0.0 GO:1903217 regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
0.0 0.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.4 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.2 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.3 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.1 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 2.2 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.1 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.0 GO:0006533 aspartate catabolic process(GO:0006533)
0.0 0.1 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.2 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.1 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.0 GO:0051866 general adaptation syndrome(GO:0051866)
0.0 0.4 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.0 GO:0044029 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.1 GO:0060160 negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.0 0.2 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 0.4 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.6 GO:0097149 centralspindlin complex(GO:0097149)
0.1 0.3 GO:0043614 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993) astrocyte end-foot(GO:0097450) glial limiting end-foot(GO:0097451)
0.1 1.3 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.2 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.1 0.2 GO:1990716 axonemal central apparatus(GO:1990716)
0.1 1.0 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 0.8 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.5 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.1 0.6 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 0.3 GO:0070826 paraferritin complex(GO:0070826)
0.1 0.2 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.1 1.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.7 GO:0070187 telosome(GO:0070187)
0.0 0.4 GO:0030430 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 0.5 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.5 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.4 GO:0033263 CORVET complex(GO:0033263)
0.0 0.5 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.8 GO:0036038 MKS complex(GO:0036038)
0.0 0.3 GO:0005827 polar microtubule(GO:0005827)
0.0 0.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.2 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.2 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.4 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.2 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.1 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.0 0.5 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.1 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.3 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.4 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.2 GO:0097452 GAIT complex(GO:0097452)
0.0 0.3 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 1.4 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.4 GO:0000800 lateral element(GO:0000800)
0.0 0.2 GO:0055028 cortical microtubule(GO:0055028)
0.0 0.3 GO:0097386 glial cell projection(GO:0097386)
0.0 0.5 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.0 GO:0031430 M band(GO:0031430)
0.0 0.4 GO:0031045 dense core granule(GO:0031045)
0.0 0.9 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.1 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.0 2.4 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.1 GO:0044294 dendrite terminus(GO:0044292) dendritic growth cone(GO:0044294)
0.0 0.1 GO:0042641 actomyosin(GO:0042641)
0.0 0.3 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.2 1.0 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.2 1.2 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.2 2.4 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.2 0.6 GO:0031626 beta-endorphin binding(GO:0031626)
0.2 0.5 GO:0008859 exoribonuclease II activity(GO:0008859)
0.1 0.4 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.1 0.5 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.1 0.5 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 0.5 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.1 0.6 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.1 0.5 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 0.6 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.1 0.3 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 0.6 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.1 0.5 GO:0030291 cAMP-dependent protein kinase inhibitor activity(GO:0004862) protein serine/threonine kinase inhibitor activity(GO:0030291)
0.1 0.2 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1 0.3 GO:0004967 glucagon receptor activity(GO:0004967)
0.1 0.6 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.4 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.1 0.3 GO:0031208 POZ domain binding(GO:0031208)
0.1 0.3 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 0.4 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 0.5 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.3 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.4 GO:0033989 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
0.1 0.2 GO:0072545 tyrosine binding(GO:0072545)
0.1 0.4 GO:0001849 complement component C1q binding(GO:0001849)
0.1 0.2 GO:0030350 iron-responsive element binding(GO:0030350)
0.1 0.3 GO:0015087 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 0.4 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.1 0.2 GO:0004827 glutamate-tRNA ligase activity(GO:0004818) proline-tRNA ligase activity(GO:0004827)
0.0 0.1 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.0 0.2 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.0 0.4 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.0 0.1 GO:0070260 tyrosyl-RNA phosphodiesterase activity(GO:0036317) 5'-tyrosyl-DNA phosphodiesterase activity(GO:0070260)
0.0 0.2 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0 1.2 GO:0031005 filamin binding(GO:0031005)
0.0 0.3 GO:0042979 ornithine decarboxylase regulator activity(GO:0042979)
0.0 0.2 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.0 0.2 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.2 GO:0016429 tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.0 1.1 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.3 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.6 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.7 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0 0.1 GO:0046921 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.0 0.1 GO:0035539 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.0 0.5 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.9 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.9 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.0 1.6 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.0 0.6 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.3 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.2 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.3 GO:0097100 supercoiled DNA binding(GO:0097100)
0.0 0.3 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.4 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 3.0 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.5 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.2 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.0 0.1 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 0.2 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.4 GO:0005537 mannose binding(GO:0005537)
0.0 0.5 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.4 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.5 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.3 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.6 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.2 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.1 GO:0005119 smoothened binding(GO:0005119)
0.0 0.3 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.1 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 0.5 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.0 0.4 GO:0008009 chemokine activity(GO:0008009)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.2 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.0 GO:0008184 nucleobase binding(GO:0002054) purine nucleobase binding(GO:0002060) glycogen phosphorylase activity(GO:0008184)
0.0 0.2 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0 0.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.0 GO:0047708 biotinidase activity(GO:0047708)
0.0 0.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.2 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.7 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.1 GO:0048020 CCR chemokine receptor binding(GO:0048020)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 4.3 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 1.1 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 1.3 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.4 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.8 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.2 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.2 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.1 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.5 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.3 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.4 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 2.7 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 5.4 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 1.1 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 2.2 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.5 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 1.0 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.3 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.7 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 1.1 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.3 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.3 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.5 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.4 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.3 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.9 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.6 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.2 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 1.4 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.3 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors