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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for FOXO3_FOXD2

Z-value: 0.66

Motif logo

Transcription factors associated with FOXO3_FOXD2

Gene Symbol Gene ID Gene Info
ENSG00000118689.10 forkhead box O3
ENSG00000186564.5 forkhead box D2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXD2hg19_v2_chr1_+_47901689_47901689-0.651.7e-01Click!
FOXO3hg19_v2_chr6_+_108977520_108977549-0.612.0e-01Click!

Activity profile of FOXO3_FOXD2 motif

Sorted Z-values of FOXO3_FOXD2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_116654376 1.61 ENST00000369500.3
mab-21-like 3 (C. elegans)
chr3_+_172468749 0.99 ENST00000366254.2
ENST00000415665.1
ENST00000438041.1
epithelial cell transforming sequence 2 oncogene
chr5_+_40841410 0.84 ENST00000381677.3
caspase recruitment domain family, member 6
chr6_-_32083106 0.83 ENST00000442721.1
tenascin XB
chr8_+_31497271 0.77 ENST00000520407.1
neuregulin 1
chr4_+_95174445 0.73 ENST00000509418.1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr7_+_106809406 0.73 ENST00000468410.1
ENST00000478930.1
ENST00000464009.1
ENST00000222574.4
HMG-box transcription factor 1
chr6_+_89791507 0.72 ENST00000354922.3
proline-rich nuclear receptor coactivator 1
chr11_+_1151573 0.72 ENST00000534821.1
ENST00000356191.2
mucin 5AC, oligomeric mucus/gel-forming
chr4_+_76871883 0.68 ENST00000599764.1
Uncharacterized protein
chr3_+_172468472 0.61 ENST00000232458.5
ENST00000392692.3
epithelial cell transforming sequence 2 oncogene
chr3_+_172468505 0.60 ENST00000427830.1
ENST00000417960.1
ENST00000428567.1
ENST00000366090.2
ENST00000426894.1
epithelial cell transforming sequence 2 oncogene
chr17_-_8059638 0.58 ENST00000584202.1
ENST00000354903.5
ENST00000577253.1
period circadian clock 1
chr2_+_172309634 0.58 ENST00000339506.3
DDB1 and CUL4 associated factor 17
chr1_+_111682058 0.58 ENST00000545121.1
choline/ethanolamine phosphotransferase 1
chr7_-_95225768 0.57 ENST00000005178.5
pyruvate dehydrogenase kinase, isozyme 4
chr5_+_78532003 0.54 ENST00000396137.4
junction mediating and regulatory protein, p53 cofactor
chr10_-_98347063 0.53 ENST00000443638.1
transmembrane 9 superfamily member 3
chr8_+_26150628 0.53 ENST00000523925.1
ENST00000315985.7
protein phosphatase 2, regulatory subunit B, alpha
chr6_-_108278456 0.52 ENST00000429168.1
SEC63 homolog (S. cerevisiae)
chr3_-_57233966 0.51 ENST00000473921.1
ENST00000295934.3
HESX homeobox 1
chr3_+_136649311 0.49 ENST00000469404.1
ENST00000467911.1
NCK adaptor protein 1
chr8_+_71485681 0.49 ENST00000391684.1
AC120194.1
chr4_+_90032651 0.48 ENST00000603357.1
RP11-84C13.1
chr12_-_772901 0.47 ENST00000305108.4
ninjurin 2
chr14_-_58894223 0.46 ENST00000555593.1
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr3_-_148939598 0.45 ENST00000455472.3
ceruloplasmin (ferroxidase)
chr15_+_96897466 0.44 ENST00000558382.1
ENST00000558499.1
RP11-522B15.3
chr9_-_98269481 0.43 ENST00000418258.1
ENST00000553011.1
ENST00000551845.1
patched 1
chr1_+_207277590 0.43 ENST00000367070.3
complement component 4 binding protein, alpha
chr14_-_58893832 0.42 ENST00000556007.2
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr2_+_28974489 0.41 ENST00000455580.1
protein phosphatase 1, catalytic subunit, beta isozyme
chr1_+_84630574 0.41 ENST00000413538.1
ENST00000417530.1
protein kinase, cAMP-dependent, catalytic, beta
chr2_+_152266604 0.41 ENST00000430328.2
RAP1 interacting factor homolog (yeast)
chr11_+_46402482 0.41 ENST00000441869.1
midkine (neurite growth-promoting factor 2)
chr2_+_152266392 0.41 ENST00000444746.2
ENST00000453091.2
ENST00000428287.2
ENST00000433166.2
ENST00000420714.3
ENST00000243326.5
ENST00000414861.2
RAP1 interacting factor homolog (yeast)
chr11_+_117049910 0.41 ENST00000431081.2
ENST00000524842.1
SID1 transmembrane family, member 2
chr1_+_120839412 0.40 ENST00000355228.4
family with sequence similarity 72, member B
chr2_+_198380763 0.40 ENST00000448447.2
ENST00000409360.1
MOB family member 4, phocein
chr7_-_112579673 0.40 ENST00000432572.1
chromosome 7 open reading frame 60
chr14_-_65569244 0.40 ENST00000557277.1
ENST00000556892.1
MYC associated factor X
chr4_-_111120334 0.38 ENST00000503885.1
ELOVL fatty acid elongase 6
chr15_+_63188009 0.38 ENST00000557900.1
RP11-1069G10.2
chr7_-_81635106 0.38 ENST00000443883.1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr4_-_164534657 0.38 ENST00000339875.5
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr2_+_196521845 0.38 ENST00000359634.5
ENST00000412905.1
solute carrier family 39 (zinc transporter), member 10
chr2_+_161993465 0.38 ENST00000457476.1
TRAF family member-associated NFKB activator
chr7_-_140340576 0.38 ENST00000275884.6
ENST00000475837.1
DENN/MADD domain containing 2A
chr4_-_165305086 0.38 ENST00000507270.1
ENST00000514618.1
ENST00000503008.1
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr14_-_24584138 0.37 ENST00000558280.1
ENST00000561028.1
neural retina leucine zipper
chr20_+_62887139 0.36 ENST00000609764.1
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
chr12_-_127630534 0.36 ENST00000535022.1
RP11-575F12.2
chr5_-_146833803 0.35 ENST00000512722.1
dihydropyrimidinase-like 3
chr5_-_142782862 0.35 ENST00000415690.2
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr14_-_23288930 0.35 ENST00000554517.1
ENST00000285850.7
ENST00000397529.2
ENST00000555702.1
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr14_+_51026926 0.34 ENST00000557735.1
atlastin GTPase 1
chr16_+_290181 0.34 ENST00000417499.1
integrin alpha FG-GAP repeat containing 3
chr17_-_39150385 0.34 ENST00000391586.1
keratin associated protein 3-3
chr17_+_9745786 0.34 ENST00000304773.5
glucagon-like peptide 2 receptor
chr1_-_201096312 0.34 ENST00000449188.2
achaete-scute family bHLH transcription factor 5
chr14_-_58893876 0.34 ENST00000555097.1
ENST00000555404.1
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr15_-_52944231 0.34 ENST00000546305.2
family with sequence similarity 214, member A
chr8_-_40755333 0.33 ENST00000297737.6
ENST00000315769.7
zinc finger, matrin-type 4
chr20_-_22559211 0.33 ENST00000564492.1
long intergenic non-protein coding RNA 261
chr1_+_199996733 0.33 ENST00000236914.3
nuclear receptor subfamily 5, group A, member 2
chr13_-_41240717 0.33 ENST00000379561.5
forkhead box O1
chr15_-_70994612 0.33 ENST00000558758.1
ENST00000379983.2
ENST00000560441.1
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr5_+_64920543 0.32 ENST00000399438.3
ENST00000510585.2
trafficking protein particle complex 13
CDNA FLJ26957 fis, clone SLV00486; Uncharacterized protein
chr14_-_58894332 0.32 ENST00000395159.2
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr4_-_105416039 0.32 ENST00000394767.2
CXXC finger protein 4
chr2_-_202298268 0.31 ENST00000440597.1
trafficking protein, kinesin binding 2
chr12_-_76462713 0.31 ENST00000552056.1
nucleosome assembly protein 1-like 1
chr1_+_84630352 0.31 ENST00000450730.1
protein kinase, cAMP-dependent, catalytic, beta
chr4_-_111120132 0.31 ENST00000506625.1
ELOVL fatty acid elongase 6
chr17_-_7082668 0.31 ENST00000573083.1
ENST00000574388.1
asialoglycoprotein receptor 1
chrX_+_78003204 0.31 ENST00000435339.3
ENST00000514744.1
lysophosphatidic acid receptor 4
chr10_-_4720333 0.30 ENST00000430998.2
long intergenic non-protein coding RNA 704
chr8_+_95908041 0.30 ENST00000396113.1
ENST00000519136.1
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr6_+_21666633 0.30 ENST00000606851.1
cancer susceptibility candidate 15 (non-protein coding)
chr6_+_135502501 0.30 ENST00000527615.1
ENST00000420123.2
ENST00000525369.1
ENST00000528774.1
ENST00000534121.1
ENST00000534044.1
ENST00000533624.1
v-myb avian myeloblastosis viral oncogene homolog
chr8_+_86999516 0.30 ENST00000521564.1
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
chr1_+_198126093 0.30 ENST00000367385.4
ENST00000442588.1
ENST00000538004.1
NIMA-related kinase 7
chr1_-_1356628 0.30 ENST00000442470.1
ENST00000537107.1
ankyrin repeat domain 65
chr6_+_88299833 0.30 ENST00000392844.3
ENST00000257789.4
ENST00000546266.1
ENST00000417380.2
origin recognition complex, subunit 3
chr10_+_111985713 0.30 ENST00000239007.7
MAX interactor 1, dimerization protein
chr18_-_53303123 0.30 ENST00000569357.1
ENST00000565124.1
ENST00000398339.1
transcription factor 4
chr14_-_102605983 0.29 ENST00000334701.7
heat shock protein 90kDa alpha (cytosolic), class A member 1
chr12_-_31479045 0.28 ENST00000539409.1
ENST00000395766.1
family with sequence similarity 60, member A
chr3_+_158288942 0.28 ENST00000491767.1
ENST00000355893.5
myeloid leukemia factor 1
chr10_+_31610064 0.28 ENST00000446923.2
ENST00000559476.1
zinc finger E-box binding homeobox 1
chr15_-_44828838 0.28 ENST00000560750.1
EIF3J antisense RNA 1 (head to head)
chr1_-_115259337 0.28 ENST00000369535.4
neuroblastoma RAS viral (v-ras) oncogene homolog
chr6_+_62284008 0.28 ENST00000544932.1
MT-RNR2-like 9 (pseudogene)
chr2_-_152146385 0.28 ENST00000414946.1
ENST00000243346.5
N-myc (and STAT) interactor
chr3_+_148447887 0.27 ENST00000475347.1
ENST00000474935.1
ENST00000461609.1
angiotensin II receptor, type 1
chr14_+_71165292 0.27 ENST00000553682.1
RP6-65G23.1
chr12_-_102591604 0.27 ENST00000329406.4
pro-melanin-concentrating hormone
chrM_+_4431 0.27 ENST00000361453.3
mitochondrially encoded NADH dehydrogenase 2
chr12_-_42878101 0.27 ENST00000552108.1
prickle homolog 1 (Drosophila)
chr2_+_105050794 0.27 ENST00000429464.1
ENST00000414442.1
ENST00000447380.1
long intergenic non-protein coding RNA 1102
chr8_-_93978216 0.26 ENST00000517751.1
ENST00000524107.1
triple QxxK/R motif containing
chr12_-_71551868 0.26 ENST00000247829.3
tetraspanin 8
chr8_-_42358742 0.26 ENST00000517366.1
solute carrier family 20 (phosphate transporter), member 2
chr3_+_187930491 0.25 ENST00000443217.1
LIM domain containing preferred translocation partner in lipoma
chr7_-_112579869 0.25 ENST00000297145.4
chromosome 7 open reading frame 60
chr5_-_41510725 0.25 ENST00000328457.3
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr8_-_128231299 0.25 ENST00000500112.1
colon cancer associated transcript 1 (non-protein coding)
chr1_-_1356719 0.25 ENST00000520296.1
ankyrin repeat domain 65
chr2_-_71454185 0.25 ENST00000244221.8
poly(A) binding protein interacting protein 2B
chr7_-_14028488 0.25 ENST00000405358.4
ets variant 1
chr17_+_57642886 0.25 ENST00000251241.4
ENST00000451169.2
ENST00000425628.3
ENST00000584385.1
ENST00000580030.1
DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr3_+_178866199 0.25 ENST00000263967.3
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
chr13_-_31038370 0.25 ENST00000399489.1
ENST00000339872.4
high mobility group box 1
chr12_+_25348186 0.25 ENST00000555711.1
ENST00000556885.1
ENST00000554266.1
ENST00000556351.1
ENST00000556927.1
ENST00000556402.1
ENST00000553788.1
LYR motif containing 5
chr2_+_149402989 0.25 ENST00000397424.2
enhancer of polycomb homolog 2 (Drosophila)
chr14_-_91526922 0.25 ENST00000418736.2
ENST00000261991.3
ribosomal protein S6 kinase, 90kDa, polypeptide 5
chr12_+_12764773 0.24 ENST00000228865.2
cAMP responsive element binding protein-like 2
chr7_-_130598059 0.24 ENST00000432045.2
microRNA 29a
chr10_-_32217717 0.24 ENST00000396144.4
ENST00000375245.4
ENST00000344936.2
ENST00000375250.5
Rho GTPase activating protein 12
chr1_+_199996702 0.24 ENST00000367362.3
nuclear receptor subfamily 5, group A, member 2
chr1_+_84629976 0.24 ENST00000446538.1
ENST00000370684.1
ENST00000436133.1
protein kinase, cAMP-dependent, catalytic, beta
chr5_-_40755987 0.24 ENST00000337702.4
tetratricopeptide repeat domain 33
chr8_+_52730143 0.23 ENST00000415643.1
Uncharacterized protein
chr6_+_74405501 0.23 ENST00000437994.2
ENST00000422508.2
CD109 molecule
chr2_+_42104692 0.23 ENST00000398796.2
ENST00000442214.1
AC104654.1
chr3_+_187930719 0.23 ENST00000312675.4
LIM domain containing preferred translocation partner in lipoma
chr9_-_88896977 0.23 ENST00000311534.6
iron-sulfur cluster assembly 1
chr6_+_74405804 0.23 ENST00000287097.5
CD109 molecule
chr14_+_58894103 0.23 ENST00000354386.6
ENST00000556134.1
KIAA0586
chr2_-_27294500 0.23 ENST00000447619.1
ENST00000429985.1
ENST00000456793.1
oligosaccharyltransferase 4 homolog (S. cerevisiae)
chr3_+_138153451 0.22 ENST00000389567.4
ENST00000289135.4
extended synaptotagmin-like protein 3
chr13_+_50589390 0.22 ENST00000360473.4
ENST00000312942.1
potassium channel regulator
chr6_-_134638767 0.22 ENST00000524929.1
serum/glucocorticoid regulated kinase 1
chr12_-_71551652 0.22 ENST00000546561.1
tetraspanin 8
chr18_+_52258390 0.22 ENST00000321600.1
dynactin associated protein
chr7_+_30174574 0.22 ENST00000409688.1
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr4_+_74606223 0.22 ENST00000307407.3
ENST00000401931.1
interleukin 8
chr2_+_189157536 0.22 ENST00000409580.1
ENST00000409637.3
GULP, engulfment adaptor PTB domain containing 1
chr2_+_64068844 0.22 ENST00000337130.5
UDP-glucose pyrophosphorylase 2
chr3_-_129375556 0.22 ENST00000510323.1
transmembrane and coiled-coil domain family 1
chr14_+_32547434 0.21 ENST00000556191.1
ENST00000554090.1
Rho GTPase activating protein 5
chr21_+_30671690 0.21 ENST00000399921.1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr2_-_191878681 0.21 ENST00000409465.1
signal transducer and activator of transcription 1, 91kDa
chr14_-_65569186 0.21 ENST00000555932.1
ENST00000358664.4
ENST00000284165.6
ENST00000358402.4
ENST00000246163.2
ENST00000556979.1
ENST00000555667.1
ENST00000557746.1
ENST00000556443.1
MYC associated factor X
chr10_+_111985837 0.21 ENST00000393134.1
MAX interactor 1, dimerization protein
chr5_+_72251857 0.21 ENST00000507345.2
ENST00000512348.1
ENST00000287761.6
FCH domain only 2
chr3_+_186330712 0.21 ENST00000411641.2
ENST00000273784.5
alpha-2-HS-glycoprotein
chr14_+_56127960 0.21 ENST00000553624.1
kinectin 1 (kinesin receptor)
chrX_+_123094369 0.21 ENST00000455404.1
ENST00000218089.9
stromal antigen 2
chr8_-_33455268 0.21 ENST00000522982.1
dual specificity phosphatase 26 (putative)
chr9_-_3469181 0.20 ENST00000366116.2
Uncharacterized protein
chr7_+_91570240 0.20 ENST00000394564.1
A kinase (PRKA) anchor protein 9
chr2_+_161993412 0.20 ENST00000259075.2
ENST00000432002.1
TRAF family member-associated NFKB activator
chr17_-_26662464 0.20 ENST00000579419.1
ENST00000585313.1
ENST00000395418.3
ENST00000578985.1
ENST00000577498.1
ENST00000585089.1
ENST00000357896.3
intraflagellar transport 20 homolog (Chlamydomonas)
chrX_-_133792480 0.20 ENST00000359237.4
placenta-specific 1
chr5_+_65222500 0.20 ENST00000511297.1
ENST00000506030.1
erbb2 interacting protein
chr3_+_158288960 0.20 ENST00000484955.1
ENST00000359117.5
ENST00000498592.1
ENST00000477042.1
ENST00000471745.1
ENST00000469452.1
myeloid leukemia factor 1
chrX_-_20237059 0.20 ENST00000457145.1
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr14_+_56127989 0.20 ENST00000555573.1
kinectin 1 (kinesin receptor)
chr2_+_173955327 0.20 ENST00000422149.1
Mitogen-activated protein kinase kinase kinase MLT
chr2_+_196440692 0.20 ENST00000458054.1
solute carrier family 39 (zinc transporter), member 10
chr8_+_86121448 0.20 ENST00000520225.1
E2F transcription factor 5, p130-binding
chr12_-_48213735 0.20 ENST00000417902.1
ENST00000417107.1
histone deacetylase 7
chr8_-_117886563 0.20 ENST00000519837.1
ENST00000522699.1
RAD21 homolog (S. pombe)
chr3_+_186158169 0.20 ENST00000435548.1
ENST00000421006.1
RP11-78H24.1
chr12_+_20963647 0.20 ENST00000381545.3
solute carrier organic anion transporter family, member 1B3
chr1_+_206138884 0.20 ENST00000341209.5
ENST00000607379.1
family with sequence similarity 72, member A
chr17_-_46657473 0.20 ENST00000332503.5
homeobox B4
chr15_-_35280426 0.20 ENST00000559564.1
ENST00000356321.4
zinc finger protein 770
chr18_+_9475585 0.20 ENST00000585015.1
ralA binding protein 1
chr1_+_24645807 0.19 ENST00000361548.4
grainyhead-like 3 (Drosophila)
chr17_-_6947225 0.19 ENST00000574600.1
ENST00000308009.1
ENST00000447225.1
solute carrier family 16, member 11
chrX_+_591524 0.19 ENST00000554971.1
ENST00000381575.1
short stature homeobox
chr2_+_170440844 0.19 ENST00000260970.3
ENST00000433207.1
ENST00000409714.3
ENST00000462903.1
peptidylprolyl isomerase G (cyclophilin G)
chr14_-_35008861 0.19 ENST00000250454.3
E2F-associated phosphoprotein
chr12_+_69202975 0.19 ENST00000544561.1
ENST00000393410.1
ENST00000299252.4
ENST00000360430.2
ENST00000517852.1
ENST00000545204.1
ENST00000393413.3
ENST00000350057.5
ENST00000348801.2
ENST00000478070.1
MDM2 oncogene, E3 ubiquitin protein ligase
chr5_-_98262240 0.19 ENST00000284049.3
chromodomain helicase DNA binding protein 1
chr21_-_35899113 0.19 ENST00000492600.1
ENST00000481448.1
ENST00000381132.2
regulator of calcineurin 1
chr16_-_84150410 0.19 ENST00000569907.1
membrane-bound transcription factor peptidase, site 1
chr11_+_111410998 0.19 ENST00000533999.1
layilin
chr8_-_99954788 0.19 ENST00000523601.1
serine/threonine kinase 3
chr2_+_196521903 0.19 ENST00000541054.1
solute carrier family 39 (zinc transporter), member 10
chr2_-_39347524 0.19 ENST00000395038.2
ENST00000402219.2
son of sevenless homolog 1 (Drosophila)
chr9_-_88897426 0.18 ENST00000375991.4
ENST00000326094.4
iron-sulfur cluster assembly 1
chr18_-_73967160 0.18 ENST00000579714.1
RP11-94B19.7
chr15_-_99057551 0.18 ENST00000558256.1
family with sequence similarity 169, member B
chr7_+_30174426 0.18 ENST00000324453.8
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr10_+_63808970 0.18 ENST00000309334.5
AT rich interactive domain 5B (MRF1-like)
chr2_+_33661382 0.18 ENST00000402538.3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr6_+_144980954 0.18 ENST00000367525.3
utrophin
chr3_+_158288999 0.18 ENST00000482628.1
ENST00000478894.2
ENST00000392822.3
ENST00000466246.1
myeloid leukemia factor 1
chr21_+_17443521 0.18 ENST00000456342.1
long intergenic non-protein coding RNA 478
chr2_+_163175394 0.18 ENST00000446271.1
ENST00000429691.2
grancalcin, EF-hand calcium binding protein
chr5_+_32788945 0.18 ENST00000326958.1
AC026703.1
chr21_+_30671189 0.18 ENST00000286800.3
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr3_-_135915401 0.18 ENST00000491050.1
male-specific lethal 2 homolog (Drosophila)
chr3_+_122513642 0.18 ENST00000261038.5
disrupted in renal carcinoma 2
chr7_+_77469439 0.18 ENST00000450574.1
ENST00000416283.2
ENST00000248550.7
putative homeodomain transcription factor 2
chr9_-_20382446 0.18 ENST00000380321.1
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr16_-_3422283 0.18 ENST00000399974.3
MT-RNR2-like 4

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXO3_FOXD2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:1903615 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.2 0.5 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.2 0.5 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.2 0.8 GO:0010157 response to chlorate(GO:0010157)
0.2 1.5 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.4 GO:1904897 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.1 0.8 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.1 0.3 GO:0098972 dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
0.1 1.0 GO:0097338 response to clozapine(GO:0097338)
0.1 0.3 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 2.2 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.1 0.4 GO:0045872 regulation of rhodopsin gene expression(GO:0007468) positive regulation of rhodopsin gene expression(GO:0045872)
0.1 0.4 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.1 0.8 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.1 0.5 GO:0030421 defecation(GO:0030421)
0.1 0.3 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.1 0.2 GO:0044029 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 0.4 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.1 0.7 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.1 0.5 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 0.6 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.2 GO:0008057 eye pigment granule organization(GO:0008057)
0.1 0.6 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.3 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.1 0.6 GO:0030450 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.1 0.3 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.1 0.7 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.8 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.2 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.1 0.2 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.1 0.2 GO:2000426 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) T-helper 1 cell activation(GO:0035711) negative regulation of apoptotic cell clearance(GO:2000426)
0.1 0.8 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.4 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 0.3 GO:0043335 protein unfolding(GO:0043335)
0.1 0.2 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.1 0.3 GO:0035947 regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947)
0.1 0.2 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 0.3 GO:2000690 regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.1 0.6 GO:0097167 circadian regulation of translation(GO:0097167)
0.1 0.7 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 0.2 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.1 0.2 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.0 0.5 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.2 GO:0043987 histone H3-S10 phosphorylation(GO:0043987)
0.0 0.2 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.0 0.6 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.1 GO:0045081 negative regulation of interleukin-10 biosynthetic process(GO:0045081)
0.0 0.4 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.0 0.3 GO:0045349 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.0 0.3 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.6 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.0 0.3 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.2 GO:1901143 insulin catabolic process(GO:1901143)
0.0 0.1 GO:0006533 aspartate catabolic process(GO:0006533)
0.0 0.4 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.2 GO:0045208 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.0 0.3 GO:0051661 maintenance of centrosome location(GO:0051661)
0.0 0.3 GO:1904721 negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.0 0.1 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
0.0 0.2 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.2 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.1 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.0 0.2 GO:1904693 midbrain morphogenesis(GO:1904693)
0.0 0.2 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.3 GO:1990822 basic amino acid transmembrane transport(GO:1990822)
0.0 0.1 GO:0044830 modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254)
0.0 0.2 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.3 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.2 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.6 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.1 GO:0061030 elastin metabolic process(GO:0051541) epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0 0.4 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.2 GO:0048539 bone marrow development(GO:0048539)
0.0 0.1 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.1 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.0 0.2 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.5 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.1 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.2 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.0 0.7 GO:0090177 establishment of planar polarity involved in neural tube closure(GO:0090177)
0.0 0.1 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.4 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.2 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 0.1 GO:0002325 natural killer cell differentiation involved in immune response(GO:0002325) regulation of natural killer cell differentiation involved in immune response(GO:0032826)
0.0 0.3 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.1 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 0.1 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.1 GO:2001153 regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
0.0 0.1 GO:0015993 molecular hydrogen transport(GO:0015993)
0.0 0.0 GO:0010901 regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
0.0 0.1 GO:0032431 positive regulation of phospholipase A2 activity(GO:0032430) activation of phospholipase A2 activity(GO:0032431)
0.0 0.2 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.1 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.3 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.1 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.3 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.5 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.1 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.0 0.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.1 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.1 GO:0035026 leading edge cell differentiation(GO:0035026)
0.0 0.0 GO:2000852 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.0 0.2 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.1 GO:0019676 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) ammonia assimilation cycle(GO:0019676) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.0 0.5 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.1 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.0 0.1 GO:0070982 L-asparagine biosynthetic process(GO:0070981) L-asparagine metabolic process(GO:0070982)
0.0 0.1 GO:0007621 negative regulation of female receptivity(GO:0007621) female courtship behavior(GO:0008050)
0.0 0.2 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.4 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.0 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.1 GO:0002005 angiotensin catabolic process in blood(GO:0002005)
0.0 0.1 GO:0033685 negative regulation of luteinizing hormone secretion(GO:0033685)
0.0 0.1 GO:1903899 lung goblet cell differentiation(GO:0060480) lobar bronchus epithelium development(GO:0060481) positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.0 0.4 GO:0006825 copper ion transport(GO:0006825)
0.0 0.1 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.1 GO:0006447 regulation of translational initiation by iron(GO:0006447)
0.0 0.2 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.2 GO:1902570 protein localization to nucleolus(GO:1902570)
0.0 0.2 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.2 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.2 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.1 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.0 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.0 0.5 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.0 0.1 GO:0032099 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.0 0.1 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.1 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.5 GO:0072600 establishment of protein localization to Golgi(GO:0072600)
0.0 0.3 GO:0036315 cellular response to sterol(GO:0036315)
0.0 0.2 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.1 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.1 GO:0072092 ureteric bud invasion(GO:0072092) metanephric renal vesicle formation(GO:0072093)
0.0 0.1 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.1 GO:0033033 negative regulation of myeloid cell apoptotic process(GO:0033033)
0.0 0.4 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.1 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.2 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.2 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.0 0.0 GO:0001897 cytolysis by symbiont of host cells(GO:0001897)
0.0 0.1 GO:0071105 response to interleukin-9(GO:0071104) response to interleukin-11(GO:0071105)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 GO:0097149 centralspindlin complex(GO:0097149)
0.3 1.5 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1 0.7 GO:0070701 mucus layer(GO:0070701)
0.1 0.3 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.1 0.8 GO:0044294 dendritic growth cone(GO:0044294)
0.1 0.9 GO:0001940 male pronucleus(GO:0001940)
0.1 0.6 GO:0000798 nuclear cohesin complex(GO:0000798)
0.1 1.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.2 GO:1902636 kinociliary basal body(GO:1902636)
0.0 0.6 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.6 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.2 GO:1990923 PET complex(GO:1990923)
0.0 0.4 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.9 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.3 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0 0.1 GO:1902737 dendritic filopodium(GO:1902737)
0.0 0.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.1 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.2 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.2 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.4 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.1 GO:0044609 DBIRD complex(GO:0044609)
0.0 0.3 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.2 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.1 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.7 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0031673 H zone(GO:0031673)
0.0 0.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.0 GO:0097651 phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.0 0.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.0 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.0 0.7 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.3 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.1 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.7 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.1 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.2 GO:0032982 myosin filament(GO:0032982)
0.0 0.1 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.1 0.6 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.1 0.6 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.4 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.1 0.6 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 0.8 GO:0005119 smoothened binding(GO:0005119)
0.1 0.5 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 0.3 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.1 0.3 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.1 0.3 GO:0004967 glucagon receptor activity(GO:0004967)
0.1 0.6 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.5 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 0.8 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.2 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 0.4 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.1 0.7 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.2 GO:0031626 beta-endorphin binding(GO:0031626)
0.1 0.4 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.4 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.1 0.2 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.4 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.2 GO:0005018 platelet-derived growth factor alpha-receptor activity(GO:0005018)
0.0 1.0 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.2 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.1 GO:0004651 polynucleotide 5'-phosphatase activity(GO:0004651)
0.0 0.1 GO:0051500 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.0 0.2 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.2 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.2 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.3 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.3 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.3 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.3 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.2 GO:0002046 opsin binding(GO:0002046)
0.0 0.2 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.2 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.2 GO:0034584 piRNA binding(GO:0034584)
0.0 0.2 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.2 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.4 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.3 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.1 GO:0047708 biotinidase activity(GO:0047708)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.4 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.5 GO:0048156 tau protein binding(GO:0048156)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.1 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.4 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.3 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.1 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 1.0 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.9 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.1 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.2 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.1 GO:0004947 bradykinin receptor activity(GO:0004947)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.3 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.2 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.1 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.0 0.1 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.0 0.2 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.1 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.1 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.4 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.2 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.1 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.0 0.1 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.4 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.2 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 2.4 GO:0008565 protein transporter activity(GO:0008565)
0.0 2.7 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.1 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.4 GO:0008198 ferrous iron binding(GO:0008198)
0.0 0.1 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.0 GO:0051373 FATZ binding(GO:0051373)
0.0 0.7 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.1 GO:0036122 BMP binding(GO:0036122)
0.0 0.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.2 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.0 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
0.0 0.1 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.1 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.2 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.2 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.4 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 1.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.0 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.1 PID MYC PATHWAY C-MYC pathway
0.0 1.4 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.6 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 0.6 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.7 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.4 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.4 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.6 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 1.8 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.1 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.0 0.7 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.3 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.8 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 2.1 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.1 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.4 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.3 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.6 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.5 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.4 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.0 REACTOME G PROTEIN BETA GAMMA SIGNALLING Genes involved in G-protein beta:gamma signalling
0.0 0.4 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.1 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.5 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 1.2 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.3 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.0 0.2 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 1.3 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.4 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.2 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon