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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for FOXA1

Z-value: 0.79

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Transcription factors associated with FOXA1

Gene Symbol Gene ID Gene Info
FOXA1
ENSG00000129514.4 forkhead box A1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXA1hg19_v2_chr14_-_38064198_380642390.424.1e-01Click!

Activity profile of FOXA1 motif

Sorted Z-values of FOXA1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_162101247 0.92 ENST00000439050.1
ENST00000436506.1
AC009299.3
AC009299.3
chr4_-_103940791 0.65 ENST00000510559.1
ENST00000394789.3
ENST00000296422.7
SLC9B1
solute carrier family 9, subfamily B (NHA1, cation proton antiporter 1), member 1
chr4_-_155533787 0.62 ENST00000407946.1
ENST00000405164.1
ENST00000336098.3
ENST00000393846.2
ENST00000404648.3
ENST00000443553.1
FGG
fibrinogen gamma chain
chr22_-_40929812 0.54 ENST00000422851.1
MKL1
megakaryoblastic leukemia (translocation) 1
chr9_-_4859260 0.49 ENST00000599351.1
AL158147.2
HCG2011465; Uncharacterized protein
chr10_+_91092241 0.48 ENST00000371811.4
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr3_-_148939598 0.47 ENST00000455472.3
CP
ceruloplasmin (ferroxidase)
chr4_+_55095428 0.46 ENST00000508170.1
ENST00000512143.1
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr1_+_116654376 0.45 ENST00000369500.3
MAB21L3
mab-21-like 3 (C. elegans)
chr3_-_148939835 0.44 ENST00000264613.6
CP
ceruloplasmin (ferroxidase)
chr12_-_89746264 0.41 ENST00000548755.1
DUSP6
dual specificity phosphatase 6
chr13_-_86373536 0.40 ENST00000400286.2
SLITRK6
SLIT and NTRK-like family, member 6
chr12_-_12714025 0.40 ENST00000539940.1
DUSP16
dual specificity phosphatase 16
chr5_+_40841410 0.39 ENST00000381677.3
CARD6
caspase recruitment domain family, member 6
chr8_-_131028869 0.38 ENST00000518283.1
ENST00000519110.1
FAM49B
family with sequence similarity 49, member B
chr17_-_46035187 0.36 ENST00000300557.2
PRR15L
proline rich 15-like
chr14_+_64970662 0.35 ENST00000556965.1
ENST00000554015.1
ZBTB1
zinc finger and BTB domain containing 1
chr1_-_1356719 0.34 ENST00000520296.1
ANKRD65
ankyrin repeat domain 65
chr12_-_92536433 0.33 ENST00000551563.2
ENST00000546975.1
ENST00000549802.1
C12orf79
chromosome 12 open reading frame 79
chr3_-_145878954 0.33 ENST00000282903.5
ENST00000360060.3
PLOD2
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr1_-_1356628 0.32 ENST00000442470.1
ENST00000537107.1
ANKRD65
ankyrin repeat domain 65
chr17_-_26694979 0.31 ENST00000438614.1
VTN
vitronectin
chr5_+_150157860 0.31 ENST00000600109.1
AC010441.1
AC010441.1
chr14_+_38065052 0.31 ENST00000556845.1
TTC6
tetratricopeptide repeat domain 6
chr14_+_56127960 0.31 ENST00000553624.1
KTN1
kinectin 1 (kinesin receptor)
chr14_+_56127989 0.30 ENST00000555573.1
KTN1
kinectin 1 (kinesin receptor)
chr5_+_32531893 0.30 ENST00000512913.1
SUB1
SUB1 homolog (S. cerevisiae)
chr8_+_126442563 0.29 ENST00000311922.3
TRIB1
tribbles pseudokinase 1
chr5_+_150157444 0.29 ENST00000526627.1
SMIM3
small integral membrane protein 3
chr2_-_165424973 0.26 ENST00000543549.1
GRB14
growth factor receptor-bound protein 14
chr5_+_169011033 0.26 ENST00000513795.1
SPDL1
spindle apparatus coiled-coil protein 1
chr1_+_35225339 0.26 ENST00000339480.1
GJB4
gap junction protein, beta 4, 30.3kDa
chr12_-_89746173 0.25 ENST00000308385.6
DUSP6
dual specificity phosphatase 6
chr4_+_165675197 0.25 ENST00000515485.1
RP11-294O2.2
RP11-294O2.2
chr14_+_64971292 0.25 ENST00000358738.3
ENST00000394712.2
ZBTB1
zinc finger and BTB domain containing 1
chr5_+_102201430 0.24 ENST00000438793.3
ENST00000346918.2
PAM
peptidylglycine alpha-amidating monooxygenase
chr3_-_25706368 0.24 ENST00000424225.1
TOP2B
topoisomerase (DNA) II beta 180kDa
chr3_+_142315225 0.23 ENST00000457734.2
ENST00000483373.1
ENST00000475296.1
ENST00000495744.1
ENST00000476044.1
ENST00000461644.1
PLS1
plastin 1
chr5_+_102201509 0.23 ENST00000348126.2
ENST00000379787.4
PAM
peptidylglycine alpha-amidating monooxygenase
chr6_+_26251835 0.23 ENST00000356350.2
HIST1H2BH
histone cluster 1, H2bh
chr11_+_65851443 0.23 ENST00000533756.1
PACS1
phosphofurin acidic cluster sorting protein 1
chr8_-_74495065 0.23 ENST00000523533.1
STAU2
staufen double-stranded RNA binding protein 2
chr16_+_21608525 0.22 ENST00000567404.1
METTL9
methyltransferase like 9
chr10_-_32217717 0.22 ENST00000396144.4
ENST00000375245.4
ENST00000344936.2
ENST00000375250.5
ARHGAP12
Rho GTPase activating protein 12
chr5_-_41510725 0.22 ENST00000328457.3
PLCXD3
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr11_+_1151573 0.22 ENST00000534821.1
ENST00000356191.2
MUC5AC
mucin 5AC, oligomeric mucus/gel-forming
chr1_-_111743285 0.21 ENST00000357640.4
DENND2D
DENN/MADD domain containing 2D
chr3_-_45957088 0.21 ENST00000539217.1
LZTFL1
leucine zipper transcription factor-like 1
chr21_-_38445011 0.21 ENST00000464265.1
ENST00000399102.1
PIGP
phosphatidylinositol glycan anchor biosynthesis, class P
chr2_+_172950227 0.21 ENST00000341900.6
DLX1
distal-less homeobox 1
chr11_-_119247004 0.21 ENST00000531070.1
USP2
ubiquitin specific peptidase 2
chr2_-_183291741 0.20 ENST00000351439.5
ENST00000409365.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr8_+_95908041 0.20 ENST00000396113.1
ENST00000519136.1
NDUFAF6
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr18_+_70536215 0.20 ENST00000578967.1
RP11-676J15.1
RP11-676J15.1
chr17_-_57229155 0.20 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr17_+_70026795 0.19 ENST00000472655.2
ENST00000538810.1
RP11-84E24.3
long intergenic non-protein coding RNA 1152
chr3_+_142315294 0.19 ENST00000464320.1
PLS1
plastin 1
chr9_-_3525968 0.19 ENST00000382004.3
ENST00000302303.1
ENST00000449190.1
RFX3
regulatory factor X, 3 (influences HLA class II expression)
chr13_-_31038370 0.18 ENST00000399489.1
ENST00000339872.4
HMGB1
high mobility group box 1
chr1_+_199996702 0.18 ENST00000367362.3
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr7_-_112579869 0.18 ENST00000297145.4
C7orf60
chromosome 7 open reading frame 60
chr14_+_64971438 0.18 ENST00000555321.1
ZBTB1
zinc finger and BTB domain containing 1
chr11_+_57308979 0.18 ENST00000457912.1
SMTNL1
smoothelin-like 1
chr5_-_133510456 0.18 ENST00000520417.1
SKP1
S-phase kinase-associated protein 1
chr1_-_115301235 0.18 ENST00000525878.1
CSDE1
cold shock domain containing E1, RNA-binding
chr2_-_166810261 0.17 ENST00000243344.7
TTC21B
tetratricopeptide repeat domain 21B
chr3_+_148447887 0.17 ENST00000475347.1
ENST00000474935.1
ENST00000461609.1
AGTR1
angiotensin II receptor, type 1
chr7_+_106415457 0.17 ENST00000490162.2
ENST00000470135.1
RP5-884M6.1
RP5-884M6.1
chr2_+_238877424 0.17 ENST00000434655.1
UBE2F
ubiquitin-conjugating enzyme E2F (putative)
chr3_+_186692745 0.17 ENST00000438590.1
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr13_+_50589390 0.17 ENST00000360473.4
ENST00000312942.1
KCNRG
potassium channel regulator
chrX_-_47863348 0.17 ENST00000376943.3
ENST00000396965.1
ENST00000305127.6
ZNF182
zinc finger protein 182
chr5_+_179921344 0.17 ENST00000261951.4
CNOT6
CCR4-NOT transcription complex, subunit 6
chr15_-_55541227 0.17 ENST00000566877.1
RAB27A
RAB27A, member RAS oncogene family
chr3_+_160394940 0.16 ENST00000320767.2
ARL14
ADP-ribosylation factor-like 14
chrX_-_20237059 0.16 ENST00000457145.1
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr1_+_35734562 0.16 ENST00000314607.6
ENST00000373297.2
ZMYM4
zinc finger, MYM-type 4
chr19_-_56047661 0.16 ENST00000344158.3
SBK2
SH3 domain binding kinase family, member 2
chr2_+_47630108 0.15 ENST00000233146.2
ENST00000454849.1
ENST00000543555.1
MSH2
mutS homolog 2
chr1_-_11107280 0.15 ENST00000400897.3
ENST00000400898.3
MASP2
mannan-binding lectin serine peptidase 2
chr2_+_58655520 0.15 ENST00000455219.3
ENST00000449448.2
AC007092.1
long intergenic non-protein coding RNA 1122
chr18_-_52626622 0.15 ENST00000591504.1
CCDC68
coiled-coil domain containing 68
chr16_-_87970122 0.15 ENST00000309893.2
CA5A
carbonic anhydrase VA, mitochondrial
chr10_-_81708854 0.15 ENST00000372292.3
SFTPD
surfactant protein D
chr1_+_40810516 0.15 ENST00000435168.2
SMAP2
small ArfGAP2
chr8_+_119294456 0.15 ENST00000366457.2
AC023590.1
Uncharacterized protein
chr16_+_4666475 0.15 ENST00000591895.1
MGRN1
mahogunin ring finger 1, E3 ubiquitin protein ligase
chr2_+_196521845 0.15 ENST00000359634.5
ENST00000412905.1
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr21_+_17443521 0.15 ENST00000456342.1
LINC00478
long intergenic non-protein coding RNA 478
chr5_-_127674883 0.14 ENST00000507835.1
FBN2
fibrillin 2
chr3_-_129407535 0.14 ENST00000432054.2
TMCC1
transmembrane and coiled-coil domain family 1
chr8_-_131028782 0.14 ENST00000519020.1
FAM49B
family with sequence similarity 49, member B
chr6_+_101847105 0.14 ENST00000369137.3
ENST00000318991.6
GRIK2
glutamate receptor, ionotropic, kainate 2
chr2_+_47630255 0.14 ENST00000406134.1
MSH2
mutS homolog 2
chr10_-_73848086 0.14 ENST00000536168.1
SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr4_-_70080449 0.14 ENST00000446444.1
UGT2B11
UDP glucuronosyltransferase 2 family, polypeptide B11
chr12_+_27849378 0.14 ENST00000310791.2
REP15
RAB15 effector protein
chr12_+_10658489 0.14 ENST00000538173.1
EIF2S3L
Putative eukaryotic translation initiation factor 2 subunit 3-like protein
chr4_+_26321284 0.14 ENST00000506956.1
ENST00000512671.1
ENST00000345843.3
ENST00000342295.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr12_-_772901 0.14 ENST00000305108.4
NINJ2
ninjurin 2
chr14_-_31926701 0.13 ENST00000310850.4
DTD2
D-tyrosyl-tRNA deacylase 2 (putative)
chr2_+_196521903 0.13 ENST00000541054.1
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chrX_-_20236970 0.13 ENST00000379548.4
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr9_-_20622478 0.13 ENST00000355930.6
ENST00000380338.4
MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr6_-_90024967 0.13 ENST00000602399.1
GABRR2
gamma-aminobutyric acid (GABA) A receptor, rho 2
chr2_-_192711968 0.13 ENST00000304141.4
SDPR
serum deprivation response
chr9_+_82186872 0.13 ENST00000376544.3
ENST00000376520.4
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr3_+_189349162 0.12 ENST00000264731.3
ENST00000382063.4
ENST00000418709.2
ENST00000320472.5
ENST00000392460.3
ENST00000440651.2
TP63
tumor protein p63
chr1_-_177939041 0.12 ENST00000308284.6
SEC16B
SEC16 homolog B (S. cerevisiae)
chr6_-_165989936 0.12 ENST00000354448.4
PDE10A
phosphodiesterase 10A
chr4_-_111119804 0.12 ENST00000394607.3
ENST00000302274.3
ELOVL6
ELOVL fatty acid elongase 6
chr1_+_199996733 0.12 ENST00000236914.3
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr4_+_56719782 0.12 ENST00000381295.2
ENST00000346134.7
ENST00000349598.6
EXOC1
exocyst complex component 1
chr10_+_51549498 0.11 ENST00000358559.2
ENST00000298239.6
MSMB
microseminoprotein, beta-
chr1_+_24646002 0.11 ENST00000356046.2
GRHL3
grainyhead-like 3 (Drosophila)
chr6_+_47666275 0.11 ENST00000327753.3
ENST00000283303.2
GPR115
G protein-coupled receptor 115
chr14_-_64971288 0.11 ENST00000394715.1
ZBTB25
zinc finger and BTB domain containing 25
chr13_+_78109804 0.11 ENST00000535157.1
SCEL
sciellin
chr5_+_138209688 0.11 ENST00000518381.1
CTNNA1
catenin (cadherin-associated protein), alpha 1, 102kDa
chr3_+_108321623 0.11 ENST00000497905.1
ENST00000463306.1
DZIP3
DAZ interacting zinc finger protein 3
chr10_+_115469134 0.11 ENST00000452490.2
CASP7
caspase 7, apoptosis-related cysteine peptidase
chr10_+_124739964 0.11 ENST00000406217.2
PSTK
phosphoseryl-tRNA kinase
chr5_-_41510656 0.11 ENST00000377801.3
PLCXD3
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr1_+_61547405 0.11 ENST00000371189.4
NFIA
nuclear factor I/A
chr2_+_152266604 0.11 ENST00000430328.2
RIF1
RAP1 interacting factor homolog (yeast)
chr7_-_107968921 0.11 ENST00000442580.1
NRCAM
neuronal cell adhesion molecule
chr1_+_24645865 0.10 ENST00000342072.4
GRHL3
grainyhead-like 3 (Drosophila)
chr5_+_179921430 0.10 ENST00000393356.1
CNOT6
CCR4-NOT transcription complex, subunit 6
chr4_-_174256276 0.10 ENST00000296503.5
HMGB2
high mobility group box 2
chr2_-_172017393 0.10 ENST00000442919.2
TLK1
tousled-like kinase 1
chr11_-_116663127 0.10 ENST00000433069.1
ENST00000542499.1
APOA5
apolipoprotein A-V
chr7_+_116165754 0.10 ENST00000405348.1
CAV1
caveolin 1, caveolae protein, 22kDa
chr6_-_31550192 0.10 ENST00000429299.2
ENST00000446745.2
LTB
lymphotoxin beta (TNF superfamily, member 3)
chr9_+_126131131 0.10 ENST00000373629.2
CRB2
crumbs homolog 2 (Drosophila)
chr15_+_96869165 0.10 ENST00000421109.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr6_-_90025011 0.10 ENST00000402938.3
GABRR2
gamma-aminobutyric acid (GABA) A receptor, rho 2
chr7_+_77469439 0.09 ENST00000450574.1
ENST00000416283.2
ENST00000248550.7
PHTF2
putative homeodomain transcription factor 2
chr19_+_16178317 0.09 ENST00000344824.6
ENST00000538887.1
TPM4
tropomyosin 4
chr3_+_141106643 0.09 ENST00000514251.1
ZBTB38
zinc finger and BTB domain containing 38
chr7_-_112579673 0.09 ENST00000432572.1
C7orf60
chromosome 7 open reading frame 60
chr4_+_187148556 0.09 ENST00000264690.6
ENST00000446598.2
ENST00000414291.1
ENST00000513864.1
KLKB1
kallikrein B, plasma (Fletcher factor) 1
chr17_-_40897043 0.09 ENST00000428826.2
ENST00000592492.1
ENST00000585893.1
ENST00000593214.1
ENST00000590078.1
ENST00000586382.1
ENST00000415827.2
ENST00000592743.1
ENST00000586089.1
ENST00000435174.1
EZH1
enhancer of zeste homolog 1 (Drosophila)
chr4_+_170581213 0.09 ENST00000507875.1
CLCN3
chloride channel, voltage-sensitive 3
chr21_+_17442799 0.09 ENST00000602580.1
ENST00000458468.1
ENST00000602935.1
LINC00478
long intergenic non-protein coding RNA 478
chr19_-_30199516 0.09 ENST00000591243.1
C19orf12
chromosome 19 open reading frame 12
chr21_+_33671264 0.09 ENST00000339944.4
MRAP
melanocortin 2 receptor accessory protein
chr5_-_142065612 0.09 ENST00000360966.5
ENST00000411960.1
FGF1
fibroblast growth factor 1 (acidic)
chr5_+_95998746 0.09 ENST00000508608.1
CAST
calpastatin
chr1_-_27240455 0.09 ENST00000254227.3
NR0B2
nuclear receptor subfamily 0, group B, member 2
chr3_-_45957534 0.09 ENST00000536047.1
LZTFL1
leucine zipper transcription factor-like 1
chr2_+_105050794 0.09 ENST00000429464.1
ENST00000414442.1
ENST00000447380.1
AC013402.2
long intergenic non-protein coding RNA 1102
chr14_-_31926623 0.08 ENST00000356180.4
DTD2
D-tyrosyl-tRNA deacylase 2 (putative)
chr4_+_86396265 0.08 ENST00000395184.1
ARHGAP24
Rho GTPase activating protein 24
chr2_-_182545603 0.08 ENST00000295108.3
NEUROD1
neuronal differentiation 1
chr7_-_84121858 0.08 ENST00000448879.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr1_+_24645807 0.08 ENST00000361548.4
GRHL3
grainyhead-like 3 (Drosophila)
chr5_+_95998673 0.08 ENST00000514845.1
CAST
calpastatin
chr14_-_38064198 0.08 ENST00000250448.2
FOXA1
forkhead box A1
chr20_-_55841398 0.08 ENST00000395864.3
BMP7
bone morphogenetic protein 7
chr11_-_102401469 0.08 ENST00000260227.4
MMP7
matrix metallopeptidase 7 (matrilysin, uterine)
chr2_-_172017343 0.08 ENST00000431350.2
ENST00000360843.3
TLK1
tousled-like kinase 1
chr13_+_78109884 0.08 ENST00000377246.3
ENST00000349847.3
SCEL
sciellin
chr11_+_107799118 0.08 ENST00000320578.2
RAB39A
RAB39A, member RAS oncogene family
chr9_+_6413317 0.08 ENST00000276893.5
ENST00000381373.3
UHRF2
ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase
chr2_+_152266392 0.08 ENST00000444746.2
ENST00000453091.2
ENST00000428287.2
ENST00000433166.2
ENST00000420714.3
ENST00000243326.5
ENST00000414861.2
RIF1
RAP1 interacting factor homolog (yeast)
chr1_+_246729724 0.08 ENST00000366513.4
ENST00000366512.3
CNST
consortin, connexin sorting protein
chr6_+_7107999 0.08 ENST00000491191.1
ENST00000379938.2
ENST00000471433.1
RREB1
ras responsive element binding protein 1
chr12_-_14849470 0.07 ENST00000261170.3
GUCY2C
guanylate cyclase 2C (heat stable enterotoxin receptor)
chr1_+_204839959 0.07 ENST00000404076.1
NFASC
neurofascin
chr22_+_21128167 0.07 ENST00000215727.5
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr2_-_69180083 0.07 ENST00000328895.4
GKN2
gastrokine 2
chr15_+_38964048 0.07 ENST00000560203.1
ENST00000557946.1
RP11-275I4.2
RP11-275I4.2
chr7_+_134576317 0.07 ENST00000424922.1
ENST00000495522.1
CALD1
caldesmon 1
chr20_-_45984401 0.07 ENST00000311275.7
ZMYND8
zinc finger, MYND-type containing 8
chr8_-_133772794 0.07 ENST00000519187.1
ENST00000523829.1
ENST00000356838.3
ENST00000377901.4
ENST00000519304.1
TMEM71
transmembrane protein 71
chrX_-_24665208 0.07 ENST00000356768.4
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr2_-_158345462 0.07 ENST00000439355.1
ENST00000540637.1
CYTIP
cytohesin 1 interacting protein
chr13_+_76334795 0.07 ENST00000526202.1
ENST00000465261.2
LMO7
LIM domain 7
chr2_-_158345341 0.06 ENST00000435117.1
CYTIP
cytohesin 1 interacting protein
chr2_+_179345173 0.06 ENST00000234453.5
PLEKHA3
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3
chrX_+_24167828 0.06 ENST00000379188.3
ENST00000419690.1
ENST00000379177.1
ENST00000304543.5
ZFX
zinc finger protein, X-linked
chr7_+_134576151 0.06 ENST00000393118.2
CALD1
caldesmon 1
chr5_+_96271141 0.06 ENST00000231368.5
LNPEP
leucyl/cystinyl aminopeptidase
chr3_+_72201910 0.06 ENST00000469178.1
ENST00000485404.1
LINC00870
long intergenic non-protein coding RNA 870
chr17_+_9728828 0.06 ENST00000262441.5
GLP2R
glucagon-like peptide 2 receptor
chr1_+_101361782 0.06 ENST00000357650.4
SLC30A7
solute carrier family 30 (zinc transporter), member 7
chr16_-_67517716 0.06 ENST00000290953.2
AGRP
agouti related protein homolog (mouse)
chr4_+_55095264 0.06 ENST00000257290.5
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr13_-_49975632 0.06 ENST00000457041.1
ENST00000355854.4
CAB39L
calcium binding protein 39-like
chr12_+_96588143 0.06 ENST00000228741.3
ENST00000547249.1
ELK3
ELK3, ETS-domain protein (SRF accessory protein 2)
chr13_+_76334567 0.06 ENST00000321797.8
LMO7
LIM domain 7
chr1_+_145883868 0.06 ENST00000447947.2
GPR89C
G protein-coupled receptor 89C
chr12_+_96588368 0.05 ENST00000547860.1
ELK3
ELK3, ETS-domain protein (SRF accessory protein 2)
chr14_-_70263979 0.05 ENST00000216540.4
SLC10A1
solute carrier family 10 (sodium/bile acid cotransporter), member 1
chrX_+_24167746 0.05 ENST00000428571.1
ENST00000539115.1
ZFX
zinc finger protein, X-linked
chr7_+_95115210 0.05 ENST00000428113.1
ENST00000325885.5
ASB4
ankyrin repeat and SOCS box containing 4
chr11_+_31833939 0.05 ENST00000530348.1
RCN1
reticulocalbin 1, EF-hand calcium binding domain
chr6_+_74405501 0.05 ENST00000437994.2
ENST00000422508.2
CD109
CD109 molecule
chr14_+_56585048 0.05 ENST00000267460.4
PELI2
pellino E3 ubiquitin protein ligase family member 2
chr16_-_68034470 0.05 ENST00000412757.2
DPEP2
dipeptidase 2

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXA1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:2000176 regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.1 0.7 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.1 0.4 GO:0045209 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.1 0.3 GO:1903567 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.1 0.3 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 0.5 GO:0018032 protein amidation(GO:0018032)
0.1 0.5 GO:2000567 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.1 0.5 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.1 0.5 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.1 0.2 GO:0021893 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.1 0.4 GO:0060005 vestibular reflex(GO:0060005)
0.1 0.4 GO:1902896 terminal web assembly(GO:1902896)
0.1 0.3 GO:1903613 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.1 0.3 GO:0010520 meiotic gene conversion(GO:0006311) regulation of reciprocal meiotic recombination(GO:0010520)
0.1 0.3 GO:0045659 eosinophil differentiation(GO:0030222) regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.1 0.5 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.2 GO:0035711 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) T-helper 1 cell activation(GO:0035711) negative regulation of apoptotic cell clearance(GO:2000426)
0.0 0.2 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 0.2 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 0.2 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.2 GO:0072560 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.0 0.3 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.5 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.1 GO:0010901 regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
0.0 0.1 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.0 0.1 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.0 0.1 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0 0.9 GO:0006825 copper ion transport(GO:0006825)
0.0 0.1 GO:0060730 regulation of intestinal epithelial structure maintenance(GO:0060730)
0.0 0.1 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.0 0.2 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0 0.2 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.1 GO:0060849 radial pattern formation(GO:0009956) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.0 0.2 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.6 GO:0031639 plasminogen activation(GO:0031639) negative regulation of platelet aggregation(GO:0090331)
0.0 0.1 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.3 GO:0042048 olfactory behavior(GO:0042048)
0.0 0.3 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.1 GO:0014028 notochord formation(GO:0014028)
0.0 0.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.3 GO:0006265 DNA topological change(GO:0006265)
0.0 0.2 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.1 GO:1901295 positive regulation of ephrin receptor signaling pathway(GO:1901189) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.3 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.1 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.1 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.3 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.1 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.1 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.1 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0 0.1 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.3 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 0.1 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0032302 MutSbeta complex(GO:0032302)
0.1 0.3 GO:0071062 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.6 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.2 GO:0070701 mucus layer(GO:0070701)
0.0 0.3 GO:1990357 terminal web(GO:1990357)
0.0 0.1 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.1 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.5 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.2 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0 0.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.6 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.2 GO:0001940 male pronucleus(GO:0001940)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.2 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.1 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0005018 platelet-derived growth factor alpha-receptor activity(GO:0005018)
0.1 0.9 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.3 GO:0032181 double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.1 0.5 GO:0023025 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.1 0.3 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.1 0.5 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.1 0.2 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1 0.2 GO:0051499 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.1 0.2 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.1 1.1 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.2 GO:0001855 complement component C4b binding(GO:0001855)
0.0 0.7 GO:0015385 sodium:proton antiporter activity(GO:0015385)
0.0 0.1 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.0 0.2 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.2 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.3 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.5 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.1 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.0 0.8 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.2 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.2 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.1 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.1 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.0 0.1 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.3 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.0 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.1 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.0 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.6 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.7 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 1.3 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.3 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide