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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for FOSB

Z-value: 0.80

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Transcription factors associated with FOSB

Gene Symbol Gene ID Gene Info
FOSB
ENSG00000125740.9 FosB proto-oncogene, AP-1 transcription factor subunit

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOSBhg19_v2_chr19_+_45971246_459712650.671.4e-01Click!

Activity profile of FOSB motif

Sorted Z-values of FOSB motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_51863853 0.66 ENST00000556762.1
RP11-255G12.3
RP11-255G12.3
chr4_+_159727272 0.58 ENST00000379346.3
FNIP2
folliculin interacting protein 2
chr9_-_34662651 0.58 ENST00000259631.4
CCL27
chemokine (C-C motif) ligand 27
chr17_-_39769005 0.51 ENST00000301653.4
ENST00000593067.1
KRT16
keratin 16
chr1_-_115880852 0.50 ENST00000369512.2
NGF
nerve growth factor (beta polypeptide)
chr1_-_21948906 0.47 ENST00000374761.2
ENST00000599760.1
RAP1GAP
RAP1 GTPase activating protein
chr10_+_17270214 0.47 ENST00000544301.1
VIM
vimentin
chr8_+_125283924 0.44 ENST00000517482.1
RP11-383J24.1
RP11-383J24.1
chr12_-_13105081 0.43 ENST00000541128.1
GPRC5D
G protein-coupled receptor, family C, group 5, member D
chr19_-_39264072 0.43 ENST00000599035.1
ENST00000378626.4
LGALS7
lectin, galactoside-binding, soluble, 7
chr1_-_223853425 0.43 ENST00000366873.2
ENST00000419193.2
CAPN8
calpain 8
chr3_-_196065248 0.42 ENST00000446879.1
ENST00000273695.3
TM4SF19
transmembrane 4 L six family member 19
chr1_-_6662919 0.41 ENST00000377658.4
ENST00000377663.3
KLHL21
kelch-like family member 21
chr6_-_44400720 0.41 ENST00000595057.1
AL133262.1
AL133262.1
chr15_+_41062159 0.40 ENST00000344320.6
C15orf62
chromosome 15 open reading frame 62
chr16_-_1429674 0.40 ENST00000403703.1
ENST00000397464.1
ENST00000402641.2
UNKL
unkempt family zinc finger-like
chr1_-_21059029 0.39 ENST00000444387.2
ENST00000375031.1
ENST00000518294.1
SH2D5
SH2 domain containing 5
chr16_-_4665023 0.39 ENST00000591897.1
UBALD1
UBA-like domain containing 1
chr18_+_21452804 0.39 ENST00000269217.6
LAMA3
laminin, alpha 3
chr19_-_56056888 0.37 ENST00000592464.1
ENST00000420723.3
SBK3
SH3 domain binding kinase family, member 3
chr3_-_52869205 0.37 ENST00000446157.2
MUSTN1
musculoskeletal, embryonic nuclear protein 1
chr17_+_75315654 0.37 ENST00000590595.1
SEPT9
septin 9
chr2_+_87755054 0.36 ENST00000423846.1
LINC00152
long intergenic non-protein coding RNA 152
chr17_+_25799008 0.35 ENST00000583370.1
ENST00000398988.3
ENST00000268763.6
KSR1
kinase suppressor of ras 1
chr17_+_79650962 0.35 ENST00000329138.4
HGS
hepatocyte growth factor-regulated tyrosine kinase substrate
chr7_+_871559 0.35 ENST00000421580.1
SUN1
Sad1 and UNC84 domain containing 1
chr7_+_134528635 0.34 ENST00000445569.2
CALD1
caldesmon 1
chr8_+_144821557 0.34 ENST00000534398.1
FAM83H-AS1
FAM83H antisense RNA 1 (head to head)
chr19_+_49377575 0.34 ENST00000600406.1
PPP1R15A
protein phosphatase 1, regulatory subunit 15A
chr4_-_122085469 0.34 ENST00000057513.3
TNIP3
TNFAIP3 interacting protein 3
chr2_+_87754989 0.33 ENST00000409898.2
ENST00000419680.2
ENST00000414584.1
ENST00000455131.1
LINC00152
long intergenic non-protein coding RNA 152
chr14_+_77425972 0.33 ENST00000553613.1
RP11-7F17.7
RP11-7F17.7
chr1_+_156096336 0.33 ENST00000504687.1
ENST00000473598.2
LMNA
lamin A/C
chr17_+_21191341 0.33 ENST00000526076.2
ENST00000361818.5
ENST00000316920.6
MAP2K3
mitogen-activated protein kinase kinase 3
chr3_+_14474178 0.32 ENST00000452775.1
SLC6A6
solute carrier family 6 (neurotransmitter transporter), member 6
chr17_+_75315534 0.32 ENST00000590294.1
ENST00000329047.8
SEPT9
septin 9
chr16_-_1429627 0.32 ENST00000248104.7
UNKL
unkempt family zinc finger-like
chr4_+_22999152 0.31 ENST00000511453.1
RP11-412P11.1
RP11-412P11.1
chr3_-_196065374 0.31 ENST00000454715.1
TM4SF19
transmembrane 4 L six family member 19
chr2_+_102618428 0.30 ENST00000457817.1
IL1R2
interleukin 1 receptor, type II
chr16_+_28875126 0.30 ENST00000359285.5
ENST00000538342.1
SH2B1
SH2B adaptor protein 1
chr4_+_159727222 0.30 ENST00000512986.1
FNIP2
folliculin interacting protein 2
chr11_-_65430251 0.30 ENST00000534283.1
ENST00000527749.1
ENST00000533187.1
ENST00000525693.1
ENST00000534558.1
ENST00000532879.1
ENST00000532999.1
RELA
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr3_+_11267691 0.29 ENST00000413416.1
HRH1
histamine receptor H1
chr19_-_44008863 0.29 ENST00000601646.1
PHLDB3
pleckstrin homology-like domain, family B, member 3
chr16_-_4664860 0.29 ENST00000587615.1
ENST00000587649.1
ENST00000590965.1
ENST00000591401.1
ENST00000283474.7
UBALD1
UBA-like domain containing 1
chr11_+_59522837 0.29 ENST00000437946.2
STX3
syntaxin 3
chr17_+_72426891 0.28 ENST00000392627.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr17_-_18908040 0.27 ENST00000388995.6
FAM83G
family with sequence similarity 83, member G
chr6_-_149806105 0.27 ENST00000389942.5
ENST00000416573.2
ENST00000542614.1
ENST00000409806.3
ZC3H12D
zinc finger CCCH-type containing 12D
chr7_+_55177416 0.27 ENST00000450046.1
ENST00000454757.2
EGFR
epidermal growth factor receptor
chr12_+_53693466 0.27 ENST00000267103.5
ENST00000548632.1
C12orf10
chromosome 12 open reading frame 10
chr11_-_9781068 0.26 ENST00000500698.1
RP11-540A21.2
RP11-540A21.2
chr8_+_87111059 0.26 ENST00000285393.3
ATP6V0D2
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
chr2_-_65593784 0.26 ENST00000443619.2
SPRED2
sprouty-related, EVH1 domain containing 2
chr1_-_24126051 0.25 ENST00000445705.1
GALE
UDP-galactose-4-epimerase
chr15_+_67418047 0.25 ENST00000540846.2
SMAD3
SMAD family member 3
chr7_+_73624276 0.25 ENST00000475494.1
ENST00000398475.1
LAT2
linker for activation of T cells family, member 2
chr1_-_235116495 0.25 ENST00000549744.1
RP11-443B7.3
RP11-443B7.3
chr4_+_3388057 0.25 ENST00000538395.1
RGS12
regulator of G-protein signaling 12
chr17_-_72864739 0.24 ENST00000579893.1
ENST00000544854.1
FDXR
ferredoxin reductase
chr17_-_38721711 0.23 ENST00000578085.1
ENST00000246657.2
CCR7
chemokine (C-C motif) receptor 7
chr3_+_183903811 0.23 ENST00000429586.2
ENST00000292808.5
ABCF3
ATP-binding cassette, sub-family F (GCN20), member 3
chr15_-_76304731 0.23 ENST00000394907.3
NRG4
neuregulin 4
chr22_-_33968239 0.23 ENST00000452586.2
ENST00000421768.1
LARGE
like-glycosyltransferase
chr1_+_223889310 0.23 ENST00000434648.1
CAPN2
calpain 2, (m/II) large subunit
chr2_-_97509729 0.23 ENST00000418232.1
ANKRD23
ankyrin repeat domain 23
chr2_-_97509749 0.23 ENST00000331001.2
ENST00000318357.4
ANKRD23
ankyrin repeat domain 23
chr1_+_156095951 0.23 ENST00000448611.2
ENST00000368297.1
LMNA
lamin A/C
chr18_+_21452964 0.23 ENST00000587184.1
LAMA3
laminin, alpha 3
chr22_+_23487513 0.22 ENST00000263116.2
ENST00000341989.4
RAB36
RAB36, member RAS oncogene family
chr17_+_80317121 0.22 ENST00000333437.4
TEX19
testis expressed 19
chr18_-_74207146 0.22 ENST00000443185.2
ZNF516
zinc finger protein 516
chr5_+_175288631 0.22 ENST00000509837.1
CPLX2
complexin 2
chrX_-_48901012 0.22 ENST00000315869.7
TFE3
transcription factor binding to IGHM enhancer 3
chr19_-_44259136 0.22 ENST00000270066.6
SMG9
SMG9 nonsense mediated mRNA decay factor
chr16_-_67867749 0.22 ENST00000566758.1
ENST00000445712.2
ENST00000219172.3
ENST00000564817.1
CENPT
centromere protein T
chr12_-_120805872 0.22 ENST00000546985.1
MSI1
musashi RNA-binding protein 1
chr1_+_223900034 0.21 ENST00000295006.5
CAPN2
calpain 2, (m/II) large subunit
chr22_-_39151434 0.21 ENST00000439339.1
SUN2
Sad1 and UNC84 domain containing 2
chr3_+_157828152 0.21 ENST00000476899.1
RSRC1
arginine/serine-rich coiled-coil 1
chr10_+_121410882 0.21 ENST00000369085.3
BAG3
BCL2-associated athanogene 3
chr7_+_100728720 0.21 ENST00000306085.6
ENST00000412507.1
TRIM56
tripartite motif containing 56
chr15_+_67458357 0.20 ENST00000537194.2
SMAD3
SMAD family member 3
chr16_+_28875268 0.20 ENST00000395532.4
SH2B1
SH2B adaptor protein 1
chr11_-_47198380 0.20 ENST00000419701.2
ENST00000526342.1
ENST00000528444.1
ENST00000530596.1
ENST00000525398.1
ENST00000319543.6
ENST00000426335.2
ENST00000527927.1
ENST00000525314.1
ARFGAP2
ADP-ribosylation factor GTPase activating protein 2
chr3_-_48632593 0.20 ENST00000454817.1
ENST00000328333.8
COL7A1
collagen, type VII, alpha 1
chr18_+_21693306 0.20 ENST00000540918.2
TTC39C
tetratricopeptide repeat domain 39C
chr7_+_28448995 0.20 ENST00000424599.1
CREB5
cAMP responsive element binding protein 5
chr6_-_127837739 0.20 ENST00000368268.2
SOGA3
SOGA family member 3
chr7_+_150065278 0.20 ENST00000519397.1
ENST00000479668.1
ENST00000540729.1
REPIN1
replication initiator 1
chr20_+_42187608 0.20 ENST00000373100.1
SGK2
serum/glucocorticoid regulated kinase 2
chr22_-_32058166 0.20 ENST00000435900.1
ENST00000336566.4
PISD
phosphatidylserine decarboxylase
chr19_-_44259053 0.20 ENST00000601170.1
SMG9
SMG9 nonsense mediated mRNA decay factor
chr2_+_74741569 0.20 ENST00000233638.7
TLX2
T-cell leukemia homeobox 2
chr3_-_32022733 0.20 ENST00000438237.2
ENST00000396556.2
OSBPL10
oxysterol binding protein-like 10
chr19_-_46285646 0.20 ENST00000458663.2
DMPK
dystrophia myotonica-protein kinase
chr5_+_145316120 0.19 ENST00000359120.4
SH3RF2
SH3 domain containing ring finger 2
chr2_+_220436917 0.19 ENST00000243786.2
INHA
inhibin, alpha
chr1_-_153935791 0.19 ENST00000429040.1
SLC39A1
solute carrier family 39 (zinc transporter), member 1
chr17_-_18161870 0.19 ENST00000579294.1
ENST00000545457.2
ENST00000379450.4
ENST00000578558.1
FLII
flightless I homolog (Drosophila)
chr12_+_7023735 0.19 ENST00000538763.1
ENST00000544774.1
ENST00000545045.2
ENO2
enolase 2 (gamma, neuronal)
chr10_-_29923893 0.19 ENST00000355867.4
SVIL
supervillin
chr6_-_31704282 0.19 ENST00000375784.3
ENST00000375779.2
CLIC1
chloride intracellular channel 1
chr11_+_394196 0.19 ENST00000331563.2
ENST00000531857.1
PKP3
plakophilin 3
chr12_+_58176525 0.18 ENST00000543727.1
ENST00000540550.1
ENST00000323833.8
ENST00000350762.5
ENST00000550559.1
ENST00000548851.1
ENST00000434359.1
ENST00000457189.1
TSFM
Ts translation elongation factor, mitochondrial
chr9_+_131902346 0.18 ENST00000432124.1
ENST00000435305.1
PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chr14_-_23426322 0.18 ENST00000555367.1
HAUS4
HAUS augmin-like complex, subunit 4
chr11_-_75201791 0.18 ENST00000529721.1
GDPD5
glycerophosphodiester phosphodiesterase domain containing 5
chr1_+_156084461 0.18 ENST00000347559.2
ENST00000361308.4
ENST00000368300.4
ENST00000368299.3
LMNA
lamin A/C
chr1_-_160231451 0.18 ENST00000495887.1
DCAF8
DDB1 and CUL4 associated factor 8
chr16_-_67281413 0.18 ENST00000258201.4
FHOD1
formin homology 2 domain containing 1
chr16_+_57662596 0.18 ENST00000567397.1
ENST00000568979.1
GPR56
G protein-coupled receptor 56
chr6_-_169563013 0.18 ENST00000439703.1
RP11-417E7.1
RP11-417E7.1
chr1_+_27189631 0.18 ENST00000339276.4
SFN
stratifin
chr12_-_49351228 0.17 ENST00000541959.1
ENST00000447318.2
ARF3
ADP-ribosylation factor 3
chr15_+_101459420 0.17 ENST00000388948.3
ENST00000284395.5
ENST00000534045.1
ENST00000532029.2
LRRK1
leucine-rich repeat kinase 1
chr19_+_47104493 0.17 ENST00000291295.9
ENST00000597743.1
CALM3
calmodulin 3 (phosphorylase kinase, delta)
chr11_-_47206965 0.17 ENST00000525725.1
PACSIN3
protein kinase C and casein kinase substrate in neurons 3
chr12_-_53625958 0.17 ENST00000327550.3
ENST00000546717.1
ENST00000425354.2
ENST00000394426.1
RARG
retinoic acid receptor, gamma
chr17_-_27405875 0.17 ENST00000359450.6
TIAF1
TGFB1-induced anti-apoptotic factor 1
chr1_-_153935738 0.17 ENST00000417348.1
SLC39A1
solute carrier family 39 (zinc transporter), member 1
chr12_+_10366223 0.17 ENST00000545290.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr17_-_73401728 0.17 ENST00000316804.5
ENST00000316615.5
GRB2
growth factor receptor-bound protein 2
chr19_-_6057282 0.17 ENST00000592281.1
RFX2
regulatory factor X, 2 (influences HLA class II expression)
chr11_+_68671310 0.17 ENST00000255078.3
ENST00000539224.1
IGHMBP2
immunoglobulin mu binding protein 2
chr1_-_24126023 0.17 ENST00000429356.1
GALE
UDP-galactose-4-epimerase
chr2_+_28615669 0.17 ENST00000379619.1
ENST00000264716.4
FOSL2
FOS-like antigen 2
chr14_-_91710852 0.17 ENST00000535815.1
ENST00000529102.1
GPR68
G protein-coupled receptor 68
chr2_-_96926313 0.17 ENST00000435268.1
TMEM127
transmembrane protein 127
chr1_-_9953295 0.16 ENST00000377258.1
CTNNBIP1
catenin, beta interacting protein 1
chr19_+_36630454 0.16 ENST00000246533.3
CAPNS1
calpain, small subunit 1
chr1_-_113247543 0.16 ENST00000414971.1
ENST00000534717.1
RHOC
ras homolog family member C
chr5_-_41794313 0.16 ENST00000512084.1
OXCT1
3-oxoacid CoA transferase 1
chr8_-_133772870 0.16 ENST00000522334.1
ENST00000519016.1
TMEM71
transmembrane protein 71
chr14_+_73525265 0.16 ENST00000525161.1
RBM25
RNA binding motif protein 25
chr9_+_131902283 0.16 ENST00000436883.1
ENST00000414510.1
PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chr11_-_65667884 0.16 ENST00000448083.2
ENST00000531493.1
ENST00000532401.1
FOSL1
FOS-like antigen 1
chr14_-_74226961 0.16 ENST00000286523.5
ENST00000435371.1
ELMSAN1
ELM2 and Myb/SANT-like domain containing 1
chr22_-_32058416 0.15 ENST00000439502.2
PISD
phosphatidylserine decarboxylase
chr8_-_123139423 0.15 ENST00000523792.1
RP11-398G24.2
RP11-398G24.2
chr16_+_89724434 0.15 ENST00000568929.1
SPATA33
spermatogenesis associated 33
chr5_-_139930713 0.15 ENST00000602657.1
SRA1
steroid receptor RNA activator 1
chr15_-_72521017 0.15 ENST00000561609.1
PKM
pyruvate kinase, muscle
chr16_+_57662419 0.15 ENST00000388812.4
ENST00000538815.1
ENST00000456916.1
ENST00000567154.1
ENST00000388813.5
ENST00000562558.1
ENST00000566271.2
GPR56
G protein-coupled receptor 56
chr12_-_118628350 0.15 ENST00000537952.1
ENST00000537822.1
TAOK3
TAO kinase 3
chr5_-_175843524 0.15 ENST00000502877.1
CLTB
clathrin, light chain B
chrX_-_153285251 0.14 ENST00000444230.1
ENST00000393682.1
ENST00000393687.2
ENST00000429936.2
ENST00000369974.2
IRAK1
interleukin-1 receptor-associated kinase 1
chr17_+_37030127 0.14 ENST00000419929.1
LASP1
LIM and SH3 protein 1
chr15_+_69373210 0.14 ENST00000435479.1
ENST00000559870.1
LINC00277
RP11-809H16.5
long intergenic non-protein coding RNA 277
RP11-809H16.5
chr11_-_102826434 0.14 ENST00000340273.4
ENST00000260302.3
MMP13
matrix metallopeptidase 13 (collagenase 3)
chr11_-_2924720 0.14 ENST00000455942.2
SLC22A18AS
solute carrier family 22 (organic cation transporter), member 18 antisense
chr17_-_79881408 0.14 ENST00000392366.3
MAFG
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
chr1_+_165796753 0.14 ENST00000367879.4
UCK2
uridine-cytidine kinase 2
chr16_+_30751953 0.14 ENST00000483578.1
RP11-2C24.4
RP11-2C24.4
chr6_-_30685214 0.14 ENST00000425072.1
MDC1
mediator of DNA-damage checkpoint 1
chr3_+_9958758 0.14 ENST00000383812.4
ENST00000438091.1
ENST00000295981.3
ENST00000436503.1
ENST00000403601.3
ENST00000416074.2
ENST00000455057.1
IL17RC
interleukin 17 receptor C
chr7_+_143078379 0.14 ENST00000449630.1
ENST00000457235.1
ZYX
zyxin
chr17_-_27503770 0.14 ENST00000533112.1
MYO18A
myosin XVIIIA
chr17_-_73401567 0.14 ENST00000392562.1
GRB2
growth factor receptor-bound protein 2
chr2_-_218766698 0.14 ENST00000439083.1
TNS1
tensin 1
chr18_+_268148 0.14 ENST00000581677.1
RP11-705O1.8
RP11-705O1.8
chrX_+_48687283 0.14 ENST00000338270.1
ERAS
ES cell expressed Ras
chr19_+_47104553 0.13 ENST00000598871.1
ENST00000594523.1
CALM3
calmodulin 3 (phosphorylase kinase, delta)
chr14_-_23426337 0.13 ENST00000342454.8
ENST00000555986.1
ENST00000541587.1
ENST00000554516.1
ENST00000347758.2
ENST00000206474.7
ENST00000555040.1
HAUS4
HAUS augmin-like complex, subunit 4
chr15_+_75335604 0.13 ENST00000563393.1
PPCDC
phosphopantothenoylcysteine decarboxylase
chr19_+_38880252 0.13 ENST00000586301.1
SPRED3
sprouty-related, EVH1 domain containing 3
chr12_+_120972606 0.13 ENST00000413266.2
RNF10
ring finger protein 10
chr10_-_47181681 0.13 ENST00000452267.1
FAM25B
family with sequence similarity 25, member B
chr2_+_87754887 0.13 ENST00000409054.1
ENST00000331944.6
ENST00000409139.1
LINC00152
long intergenic non-protein coding RNA 152
chr20_+_42187682 0.13 ENST00000373092.3
ENST00000373077.1
SGK2
serum/glucocorticoid regulated kinase 2
chr3_+_183894737 0.13 ENST00000432591.1
ENST00000431779.1
AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr19_-_36499521 0.13 ENST00000397428.3
ENST00000503121.1
ENST00000340477.5
ENST00000324444.3
ENST00000490730.1
SYNE4
spectrin repeat containing, nuclear envelope family member 4
chr11_+_10477733 0.13 ENST00000528723.1
AMPD3
adenosine monophosphate deaminase 3
chr3_-_131756559 0.12 ENST00000505957.1
CPNE4
copine IV
chr12_-_15114603 0.12 ENST00000228945.4
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr11_-_64527425 0.12 ENST00000377432.3
PYGM
phosphorylase, glycogen, muscle
chr9_+_71820057 0.12 ENST00000539225.1
TJP2
tight junction protein 2
chr1_+_27668505 0.12 ENST00000318074.5
SYTL1
synaptotagmin-like 1
chr6_+_43027595 0.12 ENST00000259708.3
ENST00000472792.1
ENST00000479388.1
ENST00000460283.1
ENST00000394056.2
KLC4
kinesin light chain 4
chr17_+_75446819 0.12 ENST00000541152.2
ENST00000591704.1
SEPT9
septin 9
chr11_-_65150103 0.12 ENST00000294187.6
ENST00000398802.1
ENST00000360662.3
ENST00000377152.2
ENST00000530936.1
SLC25A45
solute carrier family 25, member 45
chr7_-_130597935 0.12 ENST00000447307.1
ENST00000418546.1
MIR29B1
microRNA 29a
chr1_+_247579451 0.12 ENST00000391828.3
ENST00000366497.2
NLRP3
NLR family, pyrin domain containing 3
chr12_+_7023491 0.12 ENST00000541477.1
ENST00000229277.1
ENO2
enolase 2 (gamma, neuronal)
chr14_-_23426270 0.12 ENST00000557591.1
ENST00000397409.4
ENST00000490506.1
ENST00000554406.1
HAUS4
HAUS augmin-like complex, subunit 4
chr3_+_9958870 0.12 ENST00000413608.1
IL17RC
interleukin 17 receptor C
chr17_-_59668550 0.12 ENST00000521764.1
NACA2
nascent polypeptide-associated complex alpha subunit 2
chr10_+_18549645 0.11 ENST00000396576.2
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr5_+_38148582 0.11 ENST00000508853.1
CTD-2207A17.1
CTD-2207A17.1
chr9_+_71819927 0.11 ENST00000535702.1
TJP2
tight junction protein 2
chr12_-_118628315 0.11 ENST00000540561.1
TAOK3
TAO kinase 3
chr19_-_47128294 0.11 ENST00000596260.1
ENST00000597185.1
ENST00000598865.1
ENST00000594275.1
ENST00000291294.2
PTGIR
prostaglandin I2 (prostacyclin) receptor (IP)
chr11_-_8739383 0.11 ENST00000531060.1
ST5
suppression of tumorigenicity 5
chr19_-_46285736 0.11 ENST00000291270.4
ENST00000447742.2
ENST00000354227.5
DMPK
dystrophia myotonica-protein kinase
chr7_+_23286182 0.11 ENST00000258733.4
ENST00000381990.2
ENST00000409458.3
ENST00000539136.1
ENST00000453162.2
GPNMB
glycoprotein (transmembrane) nmb
chr13_-_41768654 0.11 ENST00000379483.3
KBTBD7
kelch repeat and BTB (POZ) domain containing 7
chr19_-_51587502 0.11 ENST00000156499.2
ENST00000391802.1
KLK14
kallikrein-related peptidase 14
chr5_-_141061777 0.11 ENST00000239440.4
ARAP3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr1_+_223889285 0.11 ENST00000433674.2
CAPN2
calpain 2, (m/II) large subunit

Network of associatons between targets according to the STRING database.

First level regulatory network of FOSB

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.1 0.7 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.1 0.3 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734)
0.1 0.3 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.1 0.2 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.1 0.3 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.1 0.5 GO:0032455 nerve growth factor processing(GO:0032455)
0.1 0.3 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.1 0.5 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 0.2 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 0.2 GO:0046882 negative regulation of B cell differentiation(GO:0045578) negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.0 0.6 GO:0021817 nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration(GO:0021817) nuclear migration along microtubule(GO:0030473)
0.0 0.6 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.1 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0 0.5 GO:0060297 regulation of sarcomere organization(GO:0060297)
0.0 0.2 GO:0010481 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.0 0.1 GO:0009224 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.0 0.2 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.0 0.1 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.3 GO:0032962 positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.0 0.6 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.3 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.2 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.3 GO:0035897 proteolysis in other organism(GO:0035897)
0.0 0.3 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.2 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.1 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422)
0.0 0.2 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.0 0.1 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.1 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.0 0.5 GO:0051546 keratinocyte migration(GO:0051546)
0.0 0.1 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.0 0.8 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.3 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0 0.4 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.1 GO:1905045 Schwann cell proliferation involved in axon regeneration(GO:0014011) negative regulation of Schwann cell migration(GO:1900148) regulation of Schwann cell proliferation involved in axon regeneration(GO:1905044) negative regulation of Schwann cell proliferation involved in axon regeneration(GO:1905045)
0.0 0.1 GO:0046521 sphingoid catabolic process(GO:0046521)
0.0 0.2 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.1 GO:0010624 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.0 0.1 GO:1903028 positive regulation of opsonization(GO:1903028)
0.0 0.2 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.2 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.1 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.2 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.0 GO:0060594 mammary gland specification(GO:0060594)
0.0 0.1 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.1 GO:0009608 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
0.0 0.2 GO:0007097 nuclear migration(GO:0007097)
0.0 0.1 GO:0032796 uropod organization(GO:0032796)
0.0 0.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.1 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.0 0.1 GO:2000321 positive regulation of T-helper 17 cell differentiation(GO:2000321)
0.0 0.1 GO:2000273 positive regulation of receptor activity(GO:2000273)
0.0 0.1 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.2 GO:0048484 enteric nervous system development(GO:0048484)
0.0 0.4 GO:1903543 positive regulation of exosomal secretion(GO:1903543)
0.0 0.1 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.1 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.0 0.1 GO:1904879 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.1 GO:1903012 positive regulation of bone development(GO:1903012)
0.0 0.3 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.0 0.3 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.3 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.1 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.1 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.0 0.2 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.1 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.3 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0 0.2 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.0 0.2 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.1 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.0 0.3 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.1 GO:0007320 insemination(GO:0007320)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.1 0.3 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.1 0.7 GO:0005638 lamin filament(GO:0005638)
0.1 0.3 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.1 0.2 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 0.4 GO:0033565 ESCRT-0 complex(GO:0033565)
0.1 0.6 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.3 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.4 GO:0005827 polar microtubule(GO:0005827)
0.0 0.5 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.2 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.1 GO:1902912 pyruvate kinase complex(GO:1902912)
0.0 0.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.4 GO:0070652 HAUS complex(GO:0070652)
0.0 0.8 GO:0044453 nuclear membrane part(GO:0044453)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.3 GO:0030478 actin cap(GO:0030478)
0.0 0.7 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.2 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.8 GO:0031105 septin complex(GO:0031105)
0.0 0.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.2 GO:0097413 Lewy body(GO:0097413)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.3 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.1 GO:0097513 actomyosin contractile ring(GO:0005826) myosin II filament(GO:0097513)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.2 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.2 GO:0032059 bleb(GO:0032059)
0.0 0.4 GO:0042629 mast cell granule(GO:0042629)
0.0 0.2 GO:0032797 SMN complex(GO:0032797)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.6 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.1 0.4 GO:0003978 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.1 0.2 GO:0016731 ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
0.1 0.5 GO:1990254 keratin filament binding(GO:1990254)
0.1 0.5 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.3 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.3 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.1 0.2 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 0.3 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.4 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.0 0.2 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.1 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.0 0.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.3 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.1 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.0 0.3 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.5 GO:0031432 titin binding(GO:0031432)
0.0 0.3 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.8 GO:0005165 neurotrophin receptor binding(GO:0005165)
0.0 0.3 GO:0004969 histamine receptor activity(GO:0004969)
0.0 1.1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.3 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.4 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.2 GO:0034711 inhibin binding(GO:0034711)
0.0 0.7 GO:0043495 protein anchor(GO:0043495)
0.0 0.2 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 0.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.2 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.1 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.0 0.0 GO:0051373 FATZ binding(GO:0051373)
0.0 0.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.3 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.3 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.3 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.0 0.1 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.0 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.0 0.1 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.3 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.1 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.1 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.0 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.1 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.8 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.4 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.4 PID ARF 3PATHWAY Arf1 pathway
0.0 0.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 1.2 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.5 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.8 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.4 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 1.4 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters