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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for EPAS1_BCL3

Z-value: 0.94

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Transcription factors associated with EPAS1_BCL3

Gene Symbol Gene ID Gene Info
EPAS1
ENSG00000116016.9 endothelial PAS domain protein 1
BCL3
ENSG00000069399.8 BCL3 transcription coactivator

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
BCL3hg19_v2_chr19_+_45254529_45254578-0.641.7e-01Click!
EPAS1hg19_v2_chr2_+_46524537_465245530.325.4e-01Click!

Activity profile of EPAS1_BCL3 motif

Sorted Z-values of EPAS1_BCL3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_57662596 0.86 ENST00000567397.1
ENST00000568979.1
GPR56
G protein-coupled receptor 56
chr2_+_11273179 0.68 ENST00000381585.3
ENST00000405022.3
C2orf50
chromosome 2 open reading frame 50
chr19_+_45445524 0.62 ENST00000591600.1
APOC4
apolipoprotein C-IV
chr7_-_128001658 0.61 ENST00000489835.2
ENST00000464607.1
ENST00000489517.1
ENST00000446477.2
ENST00000535159.1
ENST00000435512.1
ENST00000495931.1
PRRT4
proline-rich transmembrane protein 4
chr20_+_9049742 0.58 ENST00000437503.1
PLCB4
phospholipase C, beta 4
chr11_+_73675873 0.53 ENST00000537753.1
ENST00000542350.1
DNAJB13
DnaJ (Hsp40) homolog, subfamily B, member 13
chr4_+_183065793 0.49 ENST00000512480.1
TENM3
teneurin transmembrane protein 3
chr19_-_43835582 0.47 ENST00000595748.1
CTC-490G23.2
CTC-490G23.2
chr10_+_89124746 0.47 ENST00000465545.1
NUTM2D
NUT family member 2D
chr6_-_31620095 0.47 ENST00000424176.1
ENST00000456622.1
BAG6
BCL2-associated athanogene 6
chr12_-_66317967 0.47 ENST00000601398.1
AC090673.2
Uncharacterized protein
chr3_-_9291063 0.46 ENST00000383836.3
SRGAP3
SLIT-ROBO Rho GTPase activating protein 3
chr3_+_187957646 0.46 ENST00000457242.1
LPP
LIM domain containing preferred translocation partner in lipoma
chr4_-_175041663 0.43 ENST00000503140.1
RP11-148L24.1
RP11-148L24.1
chr11_+_111808119 0.40 ENST00000531396.1
DIXDC1
DIX domain containing 1
chr15_-_60690932 0.39 ENST00000559818.1
ANXA2
annexin A2
chr14_+_104177607 0.39 ENST00000429169.1
AL049840.1
Uncharacterized protein; cDNA FLJ53535
chr4_-_146859623 0.39 ENST00000379448.4
ENST00000513320.1
ZNF827
zinc finger protein 827
chr20_+_34680595 0.38 ENST00000406771.2
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr20_+_34680698 0.38 ENST00000447825.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr8_+_79428539 0.37 ENST00000352966.5
PKIA
protein kinase (cAMP-dependent, catalytic) inhibitor alpha
chr8_+_27348626 0.36 ENST00000517536.1
EPHX2
epoxide hydrolase 2, cytoplasmic
chr2_+_234294585 0.36 ENST00000447484.1
DGKD
diacylglycerol kinase, delta 130kDa
chr16_+_57662419 0.34 ENST00000388812.4
ENST00000538815.1
ENST00000456916.1
ENST00000567154.1
ENST00000388813.5
ENST00000562558.1
ENST00000566271.2
GPR56
G protein-coupled receptor 56
chr9_+_2017063 0.34 ENST00000457226.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr14_+_105147464 0.33 ENST00000540171.2
RP11-982M15.6
RP11-982M15.6
chr12_+_57157100 0.33 ENST00000322165.1
HSD17B6
hydroxysteroid (17-beta) dehydrogenase 6
chr14_-_91710852 0.33 ENST00000535815.1
ENST00000529102.1
GPR68
G protein-coupled receptor 68
chr18_-_74534232 0.33 ENST00000585258.1
RP11-162A12.2
Uncharacterized protein
chr2_+_102618428 0.32 ENST00000457817.1
IL1R2
interleukin 1 receptor, type II
chr11_-_75062730 0.32 ENST00000420843.2
ENST00000360025.3
ARRB1
arrestin, beta 1
chr19_+_10563567 0.32 ENST00000344979.3
PDE4A
phosphodiesterase 4A, cAMP-specific
chr2_+_220436917 0.32 ENST00000243786.2
INHA
inhibin, alpha
chr15_+_84841242 0.32 ENST00000558195.1
RP11-182J1.16
ubiquitin-conjugating enzyme E2Q family member 2-like
chr6_-_138820624 0.31 ENST00000343505.5
NHSL1
NHS-like 1
chr2_+_33701684 0.31 ENST00000442390.1
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr19_+_44037334 0.31 ENST00000314228.5
ZNF575
zinc finger protein 575
chr17_-_76732928 0.31 ENST00000589768.1
CYTH1
cytohesin 1
chr16_+_72090053 0.31 ENST00000576168.2
ENST00000567185.3
ENST00000567612.2
HP
haptoglobin
chr16_+_4845379 0.31 ENST00000588606.1
ENST00000586005.1
SMIM22
small integral membrane protein 22
chr19_+_56915668 0.30 ENST00000333201.9
ENST00000391778.3
ZNF583
zinc finger protein 583
chr16_-_21289627 0.30 ENST00000396023.2
ENST00000415987.2
CRYM
crystallin, mu
chr16_+_71660052 0.29 ENST00000567566.1
MARVELD3
MARVEL domain containing 3
chr11_+_19798964 0.28 ENST00000527559.2
NAV2
neuron navigator 2
chr19_+_14492217 0.28 ENST00000587606.1
ENST00000586517.1
ENST00000591080.1
CD97
CD97 molecule
chr1_-_21978312 0.28 ENST00000359708.4
ENST00000290101.4
RAP1GAP
RAP1 GTPase activating protein
chr17_+_4618734 0.27 ENST00000571206.1
ARRB2
arrestin, beta 2
chr11_+_19799327 0.27 ENST00000540292.1
NAV2
neuron navigator 2
chr11_+_73676281 0.27 ENST00000543947.1
DNAJB13
DnaJ (Hsp40) homolog, subfamily B, member 13
chr5_+_42423872 0.26 ENST00000230882.4
ENST00000357703.3
GHR
growth hormone receptor
chr22_+_22676808 0.26 ENST00000390290.2
IGLV1-51
immunoglobulin lambda variable 1-51
chr7_+_73442487 0.26 ENST00000380575.4
ENST00000380584.4
ENST00000458204.1
ENST00000357036.5
ENST00000417091.1
ENST00000429192.1
ENST00000442310.1
ENST00000380553.4
ENST00000380576.5
ENST00000428787.1
ENST00000320399.6
ELN
elastin
chr20_+_56964169 0.25 ENST00000475243.1
VAPB
VAMP (vesicle-associated membrane protein)-associated protein B and C
chr17_-_982198 0.25 ENST00000571945.1
ENST00000536794.2
ABR
active BCR-related
chr6_-_16761678 0.25 ENST00000244769.4
ENST00000436367.1
ATXN1
ataxin 1
chr6_-_31620149 0.24 ENST00000435080.1
ENST00000375976.4
ENST00000441054.1
BAG6
BCL2-associated athanogene 6
chr3_-_47484661 0.24 ENST00000495603.2
SCAP
SREBF chaperone
chr17_+_38296576 0.24 ENST00000264645.7
CASC3
cancer susceptibility candidate 3
chr1_+_17914907 0.24 ENST00000375420.3
ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr19_-_52227221 0.24 ENST00000222115.1
ENST00000540069.2
HAS1
hyaluronan synthase 1
chr19_+_40503013 0.23 ENST00000595225.1
ZNF546
zinc finger protein 546
chrX_-_48814810 0.23 ENST00000376488.3
ENST00000396743.3
ENST00000156084.4
OTUD5
OTU domain containing 5
chr17_+_2699697 0.23 ENST00000254695.8
ENST00000366401.4
ENST00000542807.1
RAP1GAP2
RAP1 GTPase activating protein 2
chr17_+_26638667 0.23 ENST00000600595.1
AC061975.10
Uncharacterized protein
chr6_+_153019023 0.23 ENST00000367245.5
ENST00000529453.1
MYCT1
myc target 1
chr1_+_110453462 0.23 ENST00000488198.1
CSF1
colony stimulating factor 1 (macrophage)
chr22_-_29075853 0.23 ENST00000397906.2
TTC28
tetratricopeptide repeat domain 28
chr2_+_74229812 0.22 ENST00000305799.7
TET3
tet methylcytosine dioxygenase 3
chr6_-_90121789 0.22 ENST00000359203.3
RRAGD
Ras-related GTP binding D
chr15_+_66994561 0.22 ENST00000288840.5
SMAD6
SMAD family member 6
chr19_+_14491948 0.22 ENST00000358600.3
CD97
CD97 molecule
chr6_-_90121938 0.22 ENST00000369415.4
RRAGD
Ras-related GTP binding D
chr11_-_414948 0.22 ENST00000530494.1
ENST00000528209.1
ENST00000431843.2
ENST00000528058.1
SIGIRR
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr8_+_21914348 0.22 ENST00000520174.1
DMTN
dematin actin binding protein
chr6_+_116937636 0.22 ENST00000368581.4
ENST00000229554.5
ENST00000368580.4
RSPH4A
radial spoke head 4 homolog A (Chlamydomonas)
chr3_+_52009066 0.22 ENST00000458031.2
ENST00000463937.1
ENST00000273596.3
ACY1
ABHD14A-ACY1
ABHD14A
aminoacylase 1
ABHD14A-ACY1 readthrough (NMD candidate)
abhydrolase domain containing 14A
chr15_+_82380974 0.22 ENST00000559788.1
ENST00000557838.1
RP11-597K23.2
Uncharacterized protein
chr16_-_70719925 0.22 ENST00000338779.6
MTSS1L
metastasis suppressor 1-like
chr17_+_71161140 0.22 ENST00000357585.2
SSTR2
somatostatin receptor 2
chr7_+_114055052 0.22 ENST00000462331.1
ENST00000408937.3
ENST00000403559.4
ENST00000350908.4
ENST00000393498.2
ENST00000393495.3
ENST00000378237.3
ENST00000393489.3
FOXP2
forkhead box P2
chr9_+_44990314 0.21 ENST00000377542.3
FAM27C
family with sequence similarity 27, member C
chr4_-_121993673 0.21 ENST00000379692.4
NDNF
neuron-derived neurotrophic factor
chr17_+_64961026 0.21 ENST00000262138.3
CACNG4
calcium channel, voltage-dependent, gamma subunit 4
chr20_+_51588873 0.21 ENST00000371497.5
TSHZ2
teashirt zinc finger homeobox 2
chr5_-_135701164 0.21 ENST00000355180.3
ENST00000426057.2
ENST00000513104.1
TRPC7
transient receptor potential cation channel, subfamily C, member 7
chr17_+_73089382 0.21 ENST00000538213.2
ENST00000584118.1
SLC16A5
solute carrier family 16 (monocarboxylate transporter), member 5
chr13_+_51913819 0.21 ENST00000419898.2
SERPINE3
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3
chr14_-_107083690 0.21 ENST00000455737.1
ENST00000390629.2
IGHV4-59
immunoglobulin heavy variable 4-59
chr7_-_752577 0.20 ENST00000544935.1
ENST00000430040.1
ENST00000456696.2
ENST00000406797.1
PRKAR1B
protein kinase, cAMP-dependent, regulatory, type I, beta
chrX_+_107068959 0.20 ENST00000451923.1
MID2
midline 2
chr2_+_74881432 0.20 ENST00000453930.1
SEMA4F
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
chr10_+_104154229 0.20 ENST00000428099.1
ENST00000369966.3
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr2_-_220436248 0.20 ENST00000265318.4
OBSL1
obscurin-like 1
chr6_-_31619892 0.20 ENST00000454165.1
ENST00000428326.1
ENST00000452994.1
BAG6
BCL2-associated athanogene 6
chr8_-_145691031 0.20 ENST00000424149.2
ENST00000530637.1
ENST00000306145.5
CYHR1
cysteine/histidine-rich 1
chr1_+_81106951 0.19 ENST00000443565.1
RP5-887A10.1
RP5-887A10.1
chr11_-_75062829 0.19 ENST00000393505.4
ARRB1
arrestin, beta 1
chr12_+_52643077 0.19 ENST00000553310.2
ENST00000544024.1
KRT86
keratin 86
chr6_-_31619697 0.19 ENST00000434444.1
BAG6
BCL2-associated athanogene 6
chr14_+_71108460 0.19 ENST00000256367.2
TTC9
tetratricopeptide repeat domain 9
chr6_-_31619742 0.19 ENST00000433828.1
ENST00000456286.1
BAG6
BCL2-associated athanogene 6
chr17_-_7991021 0.19 ENST00000319144.4
ALOX12B
arachidonate 12-lipoxygenase, 12R type
chr8_-_134309335 0.19 ENST00000522890.1
ENST00000323851.7
ENST00000518176.1
ENST00000354944.5
ENST00000537882.1
ENST00000522476.1
ENST00000518066.1
ENST00000521544.1
ENST00000518480.1
ENST00000523892.1
NDRG1
N-myc downstream regulated 1
chr1_-_24438664 0.19 ENST00000374434.3
ENST00000330966.7
ENST00000329601.7
MYOM3
myomesin 3
chr19_-_43709772 0.19 ENST00000596907.1
ENST00000451895.1
PSG4
pregnancy specific beta-1-glycoprotein 4
chr1_-_21671968 0.19 ENST00000415912.2
ECE1
endothelin converting enzyme 1
chr9_-_67794111 0.19 ENST00000377484.3
FAM27B
family with sequence similarity 27, member B
chr16_-_66959429 0.19 ENST00000420652.1
ENST00000299759.6
RRAD
Ras-related associated with diabetes
chr6_-_31620455 0.18 ENST00000437771.1
ENST00000404765.2
ENST00000375964.6
ENST00000211379.5
BAG6
BCL2-associated athanogene 6
chr13_+_24825824 0.18 ENST00000434675.1
ENST00000494772.1
SPATA13
spermatogenesis associated 13
chr19_+_34287751 0.18 ENST00000590771.1
ENST00000589786.1
ENST00000284006.6
ENST00000588881.1
KCTD15
potassium channel tetramerization domain containing 15
chr16_+_2285817 0.18 ENST00000564065.1
DNASE1L2
deoxyribonuclease I-like 2
chr6_-_31620403 0.18 ENST00000451898.1
ENST00000439687.2
ENST00000362049.6
ENST00000424480.1
BAG6
BCL2-associated athanogene 6
chr20_+_34680620 0.18 ENST00000430276.1
ENST00000373950.2
ENST00000452261.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr8_+_21915368 0.18 ENST00000265800.5
ENST00000517418.1
DMTN
dematin actin binding protein
chr8_-_27336747 0.18 ENST00000240132.2
ENST00000407991.1
CHRNA2
cholinergic receptor, nicotinic, alpha 2 (neuronal)
chr3_-_32022733 0.18 ENST00000438237.2
ENST00000396556.2
OSBPL10
oxysterol binding protein-like 10
chr4_-_146859787 0.18 ENST00000508784.1
ZNF827
zinc finger protein 827
chr17_-_7080227 0.18 ENST00000574330.1
ASGR1
asialoglycoprotein receptor 1
chr8_-_123793048 0.18 ENST00000607710.1
RP11-44N11.2
RP11-44N11.2
chr8_-_130587237 0.18 ENST00000520048.1
CCDC26
coiled-coil domain containing 26
chr6_+_144665237 0.18 ENST00000421035.2
UTRN
utrophin
chr11_-_89224638 0.17 ENST00000535633.1
ENST00000263317.4
NOX4
NADPH oxidase 4
chr22_+_42372970 0.17 ENST00000291236.11
SEPT3
septin 3
chr2_-_37415690 0.17 ENST00000260637.3
ENST00000535679.1
ENST00000379149.2
SULT6B1
sulfotransferase family, cytosolic, 6B, member 1
chr1_+_110453203 0.17 ENST00000357302.4
ENST00000344188.5
ENST00000329608.6
CSF1
colony stimulating factor 1 (macrophage)
chr19_+_38085768 0.17 ENST00000316433.4
ENST00000590588.1
ENST00000586134.1
ENST00000586792.1
ZNF540
zinc finger protein 540
chr12_-_57505121 0.17 ENST00000538913.2
ENST00000537215.2
ENST00000454075.3
ENST00000554825.1
ENST00000553275.1
ENST00000300134.3
STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr22_-_36236265 0.17 ENST00000414461.2
ENST00000416721.2
ENST00000449924.2
ENST00000262829.7
ENST00000397305.3
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr12_-_11036844 0.17 ENST00000428168.2
PRH1
proline-rich protein HaeIII subfamily 1
chr2_+_105760549 0.17 ENST00000436841.1
ENST00000452037.1
ENST00000438148.1
AC104655.3
AC104655.3
chr19_+_57019212 0.17 ENST00000308031.5
ENST00000591537.1
ZNF471
zinc finger protein 471
chr3_+_52009110 0.17 ENST00000491470.1
ABHD14A
abhydrolase domain containing 14A
chr10_+_123923205 0.16 ENST00000369004.3
ENST00000260733.3
TACC2
transforming, acidic coiled-coil containing protein 2
chr22_-_45404819 0.16 ENST00000447824.3
ENST00000404079.2
ENST00000420689.1
ENST00000403565.1
PHF21B
PHD finger protein 21B
chr19_+_35630628 0.16 ENST00000588715.1
ENST00000588607.1
FXYD1
FXYD domain containing ion transport regulator 1
chr19_+_14492247 0.16 ENST00000357355.3
ENST00000592261.2
ENST00000242786.5
CD97
CD97 molecule
chr12_+_26348582 0.16 ENST00000535504.1
SSPN
sarcospan
chr2_-_27341966 0.16 ENST00000402394.1
ENST00000402550.1
ENST00000260595.5
CGREF1
cell growth regulator with EF-hand domain 1
chr12_-_48226897 0.16 ENST00000434070.1
HDAC7
histone deacetylase 7
chr7_-_29234802 0.16 ENST00000449801.1
ENST00000409850.1
CPVL
carboxypeptidase, vitellogenic-like
chr16_-_1031259 0.16 ENST00000563837.1
ENST00000563863.1
ENST00000565069.1
ENST00000570014.1
RP11-161M6.2
LMF1
RP11-161M6.2
lipase maturation factor 1
chr12_-_57504975 0.16 ENST00000553397.1
ENST00000556259.1
STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr4_-_177116772 0.16 ENST00000280191.2
SPATA4
spermatogenesis associated 4
chr22_+_35776828 0.16 ENST00000216117.8
HMOX1
heme oxygenase (decycling) 1
chr19_-_6481776 0.16 ENST00000543576.1
ENST00000590173.1
ENST00000381480.2
DENND1C
DENN/MADD domain containing 1C
chrX_+_49091920 0.15 ENST00000376227.3
CCDC22
coiled-coil domain containing 22
chr19_+_36393367 0.15 ENST00000246551.4
HCST
hematopoietic cell signal transducer
chr12_+_54384370 0.15 ENST00000504315.1
HOXC6
homeobox C6
chr8_+_55370487 0.15 ENST00000297316.4
SOX17
SRY (sex determining region Y)-box 17
chr17_-_7832753 0.15 ENST00000303790.2
KCNAB3
potassium voltage-gated channel, shaker-related subfamily, beta member 3
chr22_-_30722912 0.15 ENST00000215790.7
TBC1D10A
TBC1 domain family, member 10A
chr10_-_99094458 0.15 ENST00000371019.2
FRAT2
frequently rearranged in advanced T-cell lymphomas 2
chr3_-_127542021 0.15 ENST00000434178.2
MGLL
monoglyceride lipase
chr19_+_41725140 0.15 ENST00000359092.3
AXL
AXL receptor tyrosine kinase
chr10_-_30348439 0.15 ENST00000375377.1
KIAA1462
KIAA1462
chr19_+_37960466 0.15 ENST00000589725.1
ZNF570
zinc finger protein 570
chr9_+_129089088 0.15 ENST00000361171.3
ENST00000545391.1
MVB12B
multivesicular body subunit 12B
chr17_-_3496171 0.15 ENST00000399756.4
TRPV1
transient receptor potential cation channel, subfamily V, member 1
chr1_+_153651078 0.15 ENST00000368680.3
NPR1
natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)
chr1_-_72748417 0.15 ENST00000357731.5
NEGR1
neuronal growth regulator 1
chr12_-_7261772 0.15 ENST00000545280.1
ENST00000543933.1
ENST00000545337.1
ENST00000544702.1
ENST00000266542.4
C1RL
complement component 1, r subcomponent-like
chr19_-_47734448 0.14 ENST00000439096.2
BBC3
BCL2 binding component 3
chr6_+_26365443 0.14 ENST00000527422.1
ENST00000356386.2
ENST00000396934.3
ENST00000377708.2
ENST00000396948.1
ENST00000508906.2
BTN3A2
butyrophilin, subfamily 3, member A2
chr22_+_24407642 0.14 ENST00000454754.1
ENST00000263119.5
CABIN1
calcineurin binding protein 1
chr10_+_135204338 0.14 ENST00000468317.2
RP11-108K14.8
Mitochondrial GTPase 1
chr3_+_14444063 0.14 ENST00000454876.2
ENST00000360861.3
ENST00000416216.2
SLC6A6
solute carrier family 6 (neurotransmitter transporter), member 6
chr1_+_41249539 0.14 ENST00000347132.5
ENST00000509682.2
KCNQ4
potassium voltage-gated channel, KQT-like subfamily, member 4
chr19_-_47735918 0.14 ENST00000449228.1
ENST00000300880.7
ENST00000341983.4
BBC3
BCL2 binding component 3
chr19_-_37329254 0.14 ENST00000356725.4
ZNF790
zinc finger protein 790
chr1_-_153588765 0.14 ENST00000368701.1
ENST00000344616.2
S100A14
S100 calcium binding protein A14
chr19_-_1592652 0.14 ENST00000156825.1
ENST00000434436.3
MBD3
methyl-CpG binding domain protein 3
chr17_+_73750699 0.14 ENST00000584939.1
ITGB4
integrin, beta 4
chr1_-_153917700 0.14 ENST00000368646.2
DENND4B
DENN/MADD domain containing 4B
chr17_+_45286706 0.14 ENST00000393450.1
ENST00000572303.1
MYL4
myosin, light chain 4, alkali; atrial, embryonic
chr19_-_1592828 0.14 ENST00000592012.1
MBD3
methyl-CpG binding domain protein 3
chr1_+_174769006 0.14 ENST00000489615.1
RABGAP1L
RAB GTPase activating protein 1-like
chr12_-_58027138 0.14 ENST00000341156.4
B4GALNT1
beta-1,4-N-acetyl-galactosaminyl transferase 1
chr17_+_75462485 0.14 ENST00000593189.2
SEPT9
septin 9
chr1_+_46640750 0.14 ENST00000372003.1
TSPAN1
tetraspanin 1
chr17_-_41623716 0.14 ENST00000319349.5
ETV4
ets variant 4
chr4_-_186732048 0.14 ENST00000448662.2
ENST00000439049.1
ENST00000420158.1
ENST00000431808.1
ENST00000319471.9
SORBS2
sorbin and SH3 domain containing 2
chr20_+_30946106 0.13 ENST00000375687.4
ENST00000542461.1
ASXL1
additional sex combs like 1 (Drosophila)
chr6_+_44095263 0.13 ENST00000532634.1
TMEM63B
transmembrane protein 63B
chr2_+_74881398 0.13 ENST00000339773.5
ENST00000434486.1
SEMA4F
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
chr4_-_48082192 0.13 ENST00000507351.1
TXK
TXK tyrosine kinase
chr11_-_119066545 0.13 ENST00000415318.1
CCDC153
coiled-coil domain containing 153
chr17_-_191188 0.13 ENST00000575634.1
RPH3AL
rabphilin 3A-like (without C2 domains)
chr2_+_27719697 0.13 ENST00000264717.2
ENST00000424318.2
GCKR
glucokinase (hexokinase 4) regulator
chrX_-_11284095 0.13 ENST00000303025.6
ENST00000534860.1
ARHGAP6
Rho GTPase activating protein 6
chr10_-_105421427 0.13 ENST00000538130.1
SH3PXD2A
SH3 and PX domains 2A
chr4_+_671711 0.13 ENST00000400159.2
MYL5
myosin, light chain 5, regulatory
chrX_-_71933888 0.13 ENST00000373542.4
ENST00000339490.3
ENST00000541944.1
ENST00000373539.3
ENST00000373545.3
PHKA1
phosphorylase kinase, alpha 1 (muscle)
chr5_-_158757895 0.13 ENST00000231228.2
IL12B
interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
chr10_+_123923105 0.13 ENST00000368999.1
TACC2
transforming, acidic coiled-coil containing protein 2
chr2_-_220083671 0.13 ENST00000439002.2
ABCB6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr10_+_127661942 0.13 ENST00000417114.1
ENST00000445510.1
ENST00000368691.1
FANK1
fibronectin type III and ankyrin repeat domains 1
chr19_+_9203855 0.13 ENST00000429566.3
OR1M1
olfactory receptor, family 1, subfamily M, member 1
chr22_+_24407776 0.13 ENST00000405822.2
CABIN1
calcineurin binding protein 1
chr3_-_196065374 0.13 ENST00000454715.1
TM4SF19
transmembrane 4 L six family member 19

Network of associatons between targets according to the STRING database.

First level regulatory network of EPAS1_BCL3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.7 GO:1904379 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.2 0.8 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.1 0.8 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.1 0.4 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.1 0.5 GO:0046271 phenylpropanoid catabolic process(GO:0046271)
0.1 0.4 GO:0052362 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.1 0.4 GO:0046882 negative regulation of B cell differentiation(GO:0045578) negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.1 0.3 GO:0032690 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.1 0.7 GO:0070560 protein secretion by platelet(GO:0070560)
0.1 0.2 GO:1900081 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.1 0.4 GO:1903974 mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139) positive regulation of microglial cell migration(GO:1904141)
0.1 0.2 GO:0044727 DNA demethylation of male pronucleus(GO:0044727)
0.1 0.2 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.1 0.3 GO:0003335 corneocyte development(GO:0003335)
0.1 0.3 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.1 0.3 GO:0072299 negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.1 0.2 GO:0006788 heme oxidation(GO:0006788) negative regulation of mast cell cytokine production(GO:0032764)
0.1 0.2 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.6 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
0.1 0.2 GO:0098582 innate vocalization behavior(GO:0098582)
0.1 0.4 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 0.2 GO:0072034 renal vesicle induction(GO:0072034)
0.1 0.2 GO:0042662 endodermal cell fate determination(GO:0007493) negative regulation of mesodermal cell fate specification(GO:0042662) regulation of transcription involved in primary germ layer cell fate commitment(GO:0060796) gall bladder development(GO:0061010)
0.1 0.2 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.2 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.0 0.4 GO:0071233 cellular response to leucine(GO:0071233)
0.0 0.3 GO:0006710 androgen catabolic process(GO:0006710)
0.0 0.4 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.1 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.1 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.3 GO:0046449 allantoin metabolic process(GO:0000255) creatinine metabolic process(GO:0046449)
0.0 0.3 GO:2000295 regulation of hydrogen peroxide catabolic process(GO:2000295)
0.0 0.3 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.2 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.0 0.2 GO:2000669 negative regulation of dendritic cell apoptotic process(GO:2000669)
0.0 0.1 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.1 GO:0001300 chronological cell aging(GO:0001300)
0.0 0.1 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.0 0.1 GO:1901594 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.0 0.1 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.2 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.1 GO:0097195 pilomotor reflex(GO:0097195)
0.0 0.3 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.2 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.2 GO:0010816 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 0.2 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.0 0.1 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.0 0.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.1 GO:0046022 positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.0 0.4 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.4 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.1 GO:0080120 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.0 0.4 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.1 GO:1903028 positive regulation of opsonization(GO:1903028)
0.0 0.1 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.0 0.1 GO:0042351 'de novo' GDP-L-fucose biosynthetic process(GO:0042351)
0.0 0.4 GO:1902414 protein localization to cell junction(GO:1902414)
0.0 0.1 GO:0061183 dermatome development(GO:0061054) regulation of dermatome development(GO:0061183) positive regulation of dermatome development(GO:0061184)
0.0 0.1 GO:2000330 positive regulation of T-helper 17 cell lineage commitment(GO:2000330)
0.0 0.6 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.2 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.1 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.0 0.3 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.1 GO:0052026 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.0 0.1 GO:0033058 directional locomotion(GO:0033058)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.1 GO:0045799 negative regulation of nucleobase-containing compound transport(GO:0032240) positive regulation of chromatin assembly or disassembly(GO:0045799) negative regulation of RNA export from nucleus(GO:0046832)
0.0 0.1 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.3 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.1 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0 0.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.1 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.0 0.1 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.1 GO:1990927 vesicle-mediated cholesterol transport(GO:0090119) calcium ion regulated lysosome exocytosis(GO:1990927)
0.0 0.1 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.1 GO:0019075 virus maturation(GO:0019075)
0.0 0.1 GO:1901895 negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.0 0.1 GO:0009957 epidermal cell fate specification(GO:0009957)
0.0 0.0 GO:0060722 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.0 0.1 GO:0061056 sclerotome development(GO:0061056)
0.0 0.3 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0 0.1 GO:0070272 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0 0.2 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.0 0.5 GO:0006554 lysine catabolic process(GO:0006554)
0.0 0.1 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 0.1 GO:0042494 detection of bacterial lipoprotein(GO:0042494)
0.0 0.1 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.0 0.1 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.1 GO:0040038 polar body extrusion after meiotic divisions(GO:0040038) formin-nucleated actin cable assembly(GO:0070649)
0.0 0.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.1 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.0 0.1 GO:0003409 optic cup structural organization(GO:0003409) oculomotor nerve morphogenesis(GO:0021622) oculomotor nerve formation(GO:0021623)
0.0 0.0 GO:0002309 T cell proliferation involved in immune response(GO:0002309)
0.0 0.1 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.0 0.0 GO:1904378 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.0 0.1 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.0 0.4 GO:0097264 self proteolysis(GO:0097264)
0.0 1.0 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.3 GO:0015886 heme transport(GO:0015886)
0.0 0.1 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.0 0.1 GO:0046643 regulation of gamma-delta T cell activation(GO:0046643)
0.0 0.1 GO:0070846 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.0 0.1 GO:0009956 radial pattern formation(GO:0009956)
0.0 0.1 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.0 0.0 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.0 0.0 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.0 0.1 GO:1903753 negative regulation of respiratory burst involved in inflammatory response(GO:0060266) negative regulation of respiratory burst(GO:0060268) negative regulation of p38MAPK cascade(GO:1903753)
0.0 0.1 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.3 GO:0006751 glutathione catabolic process(GO:0006751)
0.0 0.1 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.0 0.1 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.0 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.1 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.0 0.1 GO:0042441 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0 0.5 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.2 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.0 0.1 GO:0090650 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0 0.0 GO:0045083 negative regulation of interleukin-12 biosynthetic process(GO:0045083)
0.0 0.3 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 0.1 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.1 GO:0030047 actin modification(GO:0030047)
0.0 0.0 GO:0001897 cytolysis by symbiont of host cells(GO:0001897)
0.0 0.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.0 GO:0034970 histone H3-R2 methylation(GO:0034970)
0.0 0.1 GO:1901894 regulation of calcium-transporting ATPase activity(GO:1901894)
0.0 0.1 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.1 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.0 GO:0003357 noradrenergic neuron differentiation(GO:0003357) N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.4 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.2 GO:0033578 protein glycosylation in Golgi(GO:0033578) chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.0 0.2 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.0 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.0 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.0 0.1 GO:0031086 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.1 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.0 0.3 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.1 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.0 0.0 GO:0021551 central nervous system morphogenesis(GO:0021551) cardiac muscle tissue regeneration(GO:0061026)
0.0 0.2 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.1 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.1 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.1 GO:0071313 cellular response to caffeine(GO:0071313)
0.0 0.0 GO:1900175 regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145) regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900175)
0.0 0.1 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0 0.1 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.0 0.1 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
0.0 0.1 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.0 GO:0001188 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.0 0.0 GO:0070839 spleen trabecula formation(GO:0060345) divalent metal ion export(GO:0070839) iron cation export(GO:1903414) ferrous iron export(GO:1903988)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.2 GO:0035358 regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035358) positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0 0.1 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 0.4 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 0.3 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.4 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.1 0.2 GO:0005912 adherens junction(GO:0005912) anchoring junction(GO:0070161)
0.1 0.4 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.2 GO:0001534 radial spoke(GO:0001534)
0.1 0.4 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 0.2 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.2 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.1 GO:0032279 asymmetric synapse(GO:0032279) symmetric synapse(GO:0032280)
0.0 0.1 GO:0002944 cyclin K-CDK12 complex(GO:0002944)
0.0 0.3 GO:1990393 3M complex(GO:1990393)
0.0 0.2 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.0 0.1 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.1 GO:0000152 nuclear ubiquitin ligase complex(GO:0000152)
0.0 0.7 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.6 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.3 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.1 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.0 0.5 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.2 GO:0001940 male pronucleus(GO:0001940)
0.0 0.1 GO:0034385 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 0.1 GO:0031523 Myb complex(GO:0031523)
0.0 0.5 GO:0071564 npBAF complex(GO:0071564)
0.0 0.1 GO:0045298 tubulin complex(GO:0045298)
0.0 0.0 GO:0005940 septin ring(GO:0005940) septin collar(GO:0032173)
0.0 0.5 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:0034753 nuclear aryl hydrocarbon receptor complex(GO:0034753)
0.0 0.2 GO:0071953 elastic fiber(GO:0071953)
0.0 0.1 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.0 GO:0070557 PCNA-p21 complex(GO:0070557)
0.0 0.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 0.1 GO:0070435 Shc-EGFR complex(GO:0070435)
0.0 0.4 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.1 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.1 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
0.0 0.0 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.1 0.4 GO:0033149 FFAT motif binding(GO:0033149)
0.1 2.2 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.3 GO:0030492 hemoglobin binding(GO:0030492)
0.1 0.3 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.1 0.3 GO:0070698 transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity(GO:0030617) type I activin receptor binding(GO:0070698)
0.1 0.3 GO:0031691 alpha-1A adrenergic receptor binding(GO:0031691) follicle-stimulating hormone receptor binding(GO:0031762)
0.1 0.2 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.1 0.3 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.1 0.2 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 0.2 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.1 0.3 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.1 0.2 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 0.2 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 0.4 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 0.3 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.0 0.1 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.0 0.4 GO:0034711 inhibin binding(GO:0034711)
0.0 0.2 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.0 0.3 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.4 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0042356 GDP-4-dehydro-D-rhamnose reductase activity(GO:0042356) GDP-L-fucose synthase activity(GO:0050577)
0.0 0.3 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 0.2 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.3 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.1 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.0 0.1 GO:0003947 (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity(GO:0003947)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.2 GO:0005119 smoothened binding(GO:0005119)
0.0 0.1 GO:0043849 Ras palmitoyltransferase activity(GO:0043849)
0.0 0.1 GO:0016250 N-sulfoglucosamine sulfohydrolase activity(GO:0016250) hydrolase activity, acting on acid sulfur-nitrogen bonds(GO:0016826)
0.0 0.1 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.3 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0 0.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.1 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.0 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.6 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.1 GO:0004074 biliverdin reductase activity(GO:0004074)
0.0 0.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 0.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.1 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 0.2 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.0 0.3 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.6 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.1 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.0 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.0 0.1 GO:0015185 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0 0.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.1 GO:0099609 microtubule lateral binding(GO:0099609)
0.0 0.1 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.4 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.0 GO:0005549 odorant binding(GO:0005549)
0.0 0.5 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.0 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.0 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.0 0.1 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.0 0.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.1 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.1 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.1 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.1 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
0.0 0.0 GO:0032396 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107) HLA-B specific inhibitory MHC class I receptor activity(GO:0030109) inhibitory MHC class I receptor activity(GO:0032396)
0.0 0.1 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 0.1 GO:0035276 ethanol binding(GO:0035276)
0.0 0.1 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.2 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.1 GO:0043426 MRF binding(GO:0043426)
0.0 0.0 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.0 0.2 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.0 GO:0051139 metal ion:proton antiporter activity(GO:0051139)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.0 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.0 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.0 GO:0097689 iron channel activity(GO:0097689)
0.0 0.3 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.1 GO:0071253 connexin binding(GO:0071253)
0.0 0.0 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.1 GO:0042834 peptidoglycan binding(GO:0042834)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.1 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.1 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.8 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.5 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.5 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 1.0 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 0.1 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.0 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.0 0.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.8 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.7 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.8 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins