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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for EMX2
Z-value: 1.04
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Transcription factors associated with EMX2
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| EMX2 | hg19_v2_chr10_+_119301928_119301955 | -0.26 | 6.2e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr4_+_174818390 Show fit | 1.50 |
ENST00000509968.1
ENST00000512263.1 |
RP11-161D15.1 |
|
| chr15_+_63188009 Show fit | 0.85 |
ENST00000557900.1
|
RP11-1069G10.2 |
|
| chr14_+_20187174 Show fit | 0.76 |
ENST00000557414.1
|
olfactory receptor, family 4, subfamily N, member 2 |
|
| chr8_-_40200903 Show fit | 0.75 |
ENST00000522486.1
|
CTA-392C11.1 |
|
| chr11_+_327171 Show fit | 0.71 |
ENST00000534483.1
ENST00000524824.1 ENST00000531076.1 |
RP11-326C3.12 |
|
| chr2_+_172309634 Show fit | 0.63 |
ENST00000339506.3
|
DDB1 and CUL4 associated factor 17 |
|
| chr1_+_159931002 Show fit | 0.54 |
ENST00000443364.1
ENST00000423943.1 |
long intergenic non-protein coding RNA 1133 |
|
| chr11_+_12308447 Show fit | 0.53 |
ENST00000256186.2
|
MICAL C-terminal like |
|
| chr19_+_23257988 Show fit | 0.48 |
ENST00000594318.1
ENST00000600223.1 ENST00000593635.1 |
CTD-2291D10.4 zinc finger protein 730 |
|
| chr11_-_58378759 Show fit | 0.47 |
ENST00000601906.1
|
Uncharacterized protein |
Network of associatons between targets according to the STRING database.
First level regulatory network of EMX2
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.6 | GO:0010730 | negative regulation of hydrogen peroxide biosynthetic process(GO:0010730) |
| 0.0 | 0.5 | GO:0060287 | epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287) |
| 0.0 | 0.5 | GO:0006491 | N-glycan processing(GO:0006491) |
| 0.0 | 0.4 | GO:0098532 | histone H3-K27 trimethylation(GO:0098532) |
| 0.0 | 0.4 | GO:0046485 | ether lipid metabolic process(GO:0046485) |
| 0.1 | 0.3 | GO:0050717 | positive regulation of interleukin-1 alpha secretion(GO:0050717) |
| 0.1 | 0.3 | GO:0016095 | polyprenol catabolic process(GO:0016095) |
| 0.1 | 0.3 | GO:0015692 | lead ion transport(GO:0015692) |
| 0.0 | 0.3 | GO:0010735 | positive regulation of transcription via serum response element binding(GO:0010735) |
| 0.0 | 0.3 | GO:0035278 | miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.6 | GO:0097179 | protease inhibitor complex(GO:0097179) |
| 0.0 | 0.6 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
| 0.1 | 0.3 | GO:0070826 | paraferritin complex(GO:0070826) |
| 0.0 | 0.2 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
| 0.0 | 0.2 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
| 0.0 | 0.1 | GO:1990075 | kinesin II complex(GO:0016939) periciliary membrane compartment(GO:1990075) |
| 0.0 | 0.1 | GO:0005726 | perichromatin fibrils(GO:0005726) |
| 0.0 | 0.1 | GO:1990131 | Gtr1-Gtr2 GTPase complex(GO:1990131) |
| 0.0 | 0.1 | GO:0005958 | DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) |
| 0.0 | 0.1 | GO:0032584 | growth cone membrane(GO:0032584) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.6 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
| 0.0 | 0.6 | GO:0005527 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 0.1 | 0.5 | GO:0008454 | alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454) |
| 0.0 | 0.5 | GO:0050700 | CARD domain binding(GO:0050700) |
| 0.1 | 0.4 | GO:0052740 | 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740) |
| 0.0 | 0.4 | GO:0015125 | bile acid transmembrane transporter activity(GO:0015125) |
| 0.0 | 0.4 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.1 | 0.3 | GO:0033765 | 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751) |
| 0.1 | 0.3 | GO:0015086 | cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639) |
| 0.1 | 0.2 | GO:0072545 | tyrosine binding(GO:0072545) |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.6 | REACTOME N GLYCAN ANTENNAE ELONGATION | Genes involved in N-Glycan antennae elongation |
| 0.0 | 0.4 | REACTOME ACYL CHAIN REMODELLING OF PS | Genes involved in Acyl chain remodelling of PS |
| 0.0 | 0.4 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
| 0.0 | 0.3 | REACTOME ANDROGEN BIOSYNTHESIS | Genes involved in Androgen biosynthesis |
| 0.0 | 0.2 | REACTOME SEROTONIN RECEPTORS | Genes involved in Serotonin receptors |
| 0.0 | 0.1 | REACTOME HORMONE LIGAND BINDING RECEPTORS | Genes involved in Hormone ligand-binding receptors |