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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for EGR3_EGR2

Z-value: 0.88

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Transcription factors associated with EGR3_EGR2

Gene Symbol Gene ID Gene Info
EGR3
ENSG00000179388.8 early growth response 3
EGR2
ENSG00000122877.9 early growth response 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EGR3hg19_v2_chr8_-_22550815_22550844-0.641.7e-01Click!
EGR2hg19_v2_chr10_-_64576105_64576133-0.118.4e-01Click!

Activity profile of EGR3_EGR2 motif

Sorted Z-values of EGR3_EGR2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_49565254 0.52 ENST00000593537.1
NTF4
neurotrophin 4
chrX_-_16888276 0.52 ENST00000493145.1
RBBP7
retinoblastoma binding protein 7
chr4_-_90758227 0.47 ENST00000506691.1
ENST00000394986.1
ENST00000506244.1
ENST00000394989.2
ENST00000394991.3
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr1_+_23695680 0.47 ENST00000454117.1
ENST00000335648.3
ENST00000518821.1
ENST00000437367.2
C1orf213
chromosome 1 open reading frame 213
chr12_-_57634475 0.44 ENST00000393825.1
NDUFA4L2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr2_-_239149300 0.44 ENST00000436051.1
HES6
hes family bHLH transcription factor 6
chr19_+_49617581 0.42 ENST00000391864.3
LIN7B
lin-7 homolog B (C. elegans)
chr14_+_23352374 0.38 ENST00000267396.4
ENST00000536884.1
REM2
RAS (RAD and GEM)-like GTP binding 2
chr9_-_33264676 0.36 ENST00000472232.3
ENST00000379704.2
BAG1
BCL2-associated athanogene
chr4_+_83351715 0.36 ENST00000273920.3
ENOPH1
enolase-phosphatase 1
chr9_-_130742792 0.35 ENST00000373095.1
FAM102A
family with sequence similarity 102, member A
chr17_+_79008940 0.34 ENST00000392411.3
ENST00000575989.1
ENST00000321280.7
ENST00000428708.2
ENST00000575712.1
ENST00000575245.1
ENST00000435091.3
ENST00000321300.6
BAIAP2
BAI1-associated protein 2
chr1_+_43148059 0.33 ENST00000321358.7
ENST00000332220.6
YBX1
Y box binding protein 1
chr19_+_41860047 0.32 ENST00000604123.1
TMEM91
transmembrane protein 91
chr19_+_10531150 0.32 ENST00000352831.6
PDE4A
phosphodiesterase 4A, cAMP-specific
chr1_+_51434357 0.32 ENST00000396148.1
CDKN2C
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr17_+_47439733 0.32 ENST00000507337.1
RP11-1079K10.3
RP11-1079K10.3
chr19_+_51815102 0.32 ENST00000270642.8
IGLON5
IgLON family member 5
chr1_+_43148625 0.31 ENST00000436427.1
YBX1
Y box binding protein 1
chr20_-_61051026 0.30 ENST00000252997.2
GATA5
GATA binding protein 5
chr9_-_33264557 0.30 ENST00000473781.1
ENST00000488499.1
BAG1
BCL2-associated athanogene
chr17_-_47439437 0.29 ENST00000430262.2
ZNF652
zinc finger protein 652
chr1_+_156698743 0.29 ENST00000524343.1
RRNAD1
ribosomal RNA adenine dimethylase domain containing 1
chr19_-_39264072 0.28 ENST00000599035.1
ENST00000378626.4
LGALS7
lectin, galactoside-binding, soluble, 7
chr2_-_152118276 0.28 ENST00000409092.1
RBM43
RNA binding motif protein 43
chr8_+_145321517 0.27 ENST00000340210.1
SCXB
scleraxis homolog B (mouse)
chr4_+_83351791 0.26 ENST00000509635.1
ENOPH1
enolase-phosphatase 1
chr11_+_118978045 0.26 ENST00000336702.3
C2CD2L
C2CD2-like
chr14_-_23770683 0.26 ENST00000561437.1
ENST00000559942.1
ENST00000560913.1
ENST00000559314.1
ENST00000558058.1
PPP1R3E
protein phosphatase 1, regulatory subunit 3E
chr2_+_177502438 0.25 ENST00000443670.1
AC017048.4
long intergenic non-protein coding RNA 1117
chr17_-_4890649 0.25 ENST00000361571.5
CAMTA2
calmodulin binding transcription activator 2
chr14_+_66975213 0.25 ENST00000543237.1
ENST00000305960.9
GPHN
gephyrin
chr3_+_71803201 0.25 ENST00000304411.2
GPR27
G protein-coupled receptor 27
chr16_-_31021921 0.25 ENST00000215095.5
STX1B
syntaxin 1B
chr19_+_10400615 0.25 ENST00000221980.4
ICAM5
intercellular adhesion molecule 5, telencephalin
chr6_-_112194484 0.25 ENST00000518295.1
ENST00000484067.2
ENST00000229470.5
ENST00000356013.2
ENST00000368678.4
ENST00000523238.1
ENST00000354650.3
FYN
FYN oncogene related to SRC, FGR, YES
chr8_+_144821557 0.24 ENST00000534398.1
FAM83H-AS1
FAM83H antisense RNA 1 (head to head)
chr1_-_161147275 0.24 ENST00000319769.5
ENST00000367998.1
B4GALT3
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3
chr1_-_94312706 0.24 ENST00000370244.1
BCAR3
breast cancer anti-estrogen resistance 3
chr17_-_31404 0.24 ENST00000343572.7
DOC2B
double C2-like domains, beta
chr15_-_72410455 0.23 ENST00000569314.1
MYO9A
myosin IXA
chr11_-_65548265 0.23 ENST00000532090.2
AP5B1
adaptor-related protein complex 5, beta 1 subunit
chr19_+_37341752 0.23 ENST00000586933.1
ENST00000532141.1
ENST00000420450.1
ENST00000526123.1
ZNF345
zinc finger protein 345
chr17_+_75369400 0.23 ENST00000590059.1
SEPT9
septin 9
chr3_-_138048653 0.23 ENST00000460099.1
NME9
NME/NM23 family member 9
chr17_+_59477233 0.22 ENST00000240328.3
TBX2
T-box 2
chr14_-_21566731 0.22 ENST00000360947.3
ZNF219
zinc finger protein 219
chr19_-_14201776 0.22 ENST00000269724.5
SAMD1
sterile alpha motif domain containing 1
chr19_+_41882466 0.22 ENST00000436170.2
TMEM91
transmembrane protein 91
chr16_-_54962625 0.21 ENST00000559432.1
CRNDE
colorectal neoplasia differentially expressed (non-protein coding)
chr3_-_71803917 0.21 ENST00000421769.2
EIF4E3
eukaryotic translation initiation factor 4E family member 3
chr4_+_53525573 0.21 ENST00000503051.1
USP46-AS1
USP46 antisense RNA 1
chr6_+_43739697 0.21 ENST00000230480.6
VEGFA
vascular endothelial growth factor A
chr17_-_4890919 0.21 ENST00000572543.1
ENST00000381311.5
ENST00000348066.3
ENST00000358183.4
CAMTA2
calmodulin binding transcription activator 2
chr2_+_30454390 0.21 ENST00000395323.3
ENST00000406087.1
ENST00000404397.1
LBH
limb bud and heart development
chr16_-_31021717 0.21 ENST00000565419.1
STX1B
syntaxin 1B
chr2_-_74781061 0.21 ENST00000264094.3
ENST00000393937.2
ENST00000409986.1
LOXL3
lysyl oxidase-like 3
chr14_+_100531615 0.20 ENST00000392920.3
EVL
Enah/Vasp-like
chr16_+_29690358 0.20 ENST00000395384.4
ENST00000562473.1
QPRT
quinolinate phosphoribosyltransferase
chr3_-_71803474 0.20 ENST00000448225.1
ENST00000496214.2
EIF4E3
eukaryotic translation initiation factor 4E family member 3
chr7_+_150782945 0.20 ENST00000463381.1
AGAP3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr7_+_28448995 0.20 ENST00000424599.1
CREB5
cAMP responsive element binding protein 5
chr7_-_27213893 0.18 ENST00000283921.4
HOXA10
homeobox A10
chr3_+_149689066 0.18 ENST00000593416.1
AC117395.1
LOC646903 protein; Uncharacterized protein
chr16_+_2285817 0.18 ENST00000564065.1
DNASE1L2
deoxyribonuclease I-like 2
chr1_+_161494036 0.18 ENST00000309758.4
HSPA6
heat shock 70kDa protein 6 (HSP70B')
chr1_+_178994939 0.17 ENST00000440702.1
FAM20B
family with sequence similarity 20, member B
chr13_-_45151259 0.17 ENST00000493016.1
TSC22D1
TSC22 domain family, member 1
chr15_-_72612470 0.17 ENST00000287202.5
CELF6
CUGBP, Elav-like family member 6
chr14_+_91526668 0.17 ENST00000521334.1
C14orf159
chromosome 14 open reading frame 159
chr14_-_69445968 0.17 ENST00000438964.2
ACTN1
actinin, alpha 1
chr14_+_102027688 0.17 ENST00000510508.4
ENST00000359323.3
DIO3
deiodinase, iodothyronine, type III
chrX_-_19905577 0.17 ENST00000379697.3
SH3KBP1
SH3-domain kinase binding protein 1
chr16_+_3070313 0.17 ENST00000326577.4
TNFRSF12A
tumor necrosis factor receptor superfamily, member 12A
chr21_+_35014829 0.17 ENST00000451686.1
ITSN1
intersectin 1 (SH3 domain protein)
chr19_+_49617609 0.17 ENST00000221459.2
ENST00000486217.2
LIN7B
lin-7 homolog B (C. elegans)
chr17_+_72428218 0.17 ENST00000392628.2
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr22_-_30722912 0.17 ENST00000215790.7
TBC1D10A
TBC1 domain family, member 10A
chr16_-_28621298 0.17 ENST00000566189.1
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr14_+_66974845 0.17 ENST00000459628.1
GPHN
gephyrin
chr1_+_156698708 0.16 ENST00000519086.1
RRNAD1
ribosomal RNA adenine dimethylase domain containing 1
chr11_-_64546202 0.16 ENST00000377390.3
ENST00000227503.9
ENST00000377394.3
ENST00000422298.2
ENST00000334944.5
SF1
splicing factor 1
chr14_-_69658127 0.16 ENST00000556182.1
RP11-363J20.1
RP11-363J20.1
chr15_+_91446157 0.16 ENST00000559717.1
MAN2A2
mannosidase, alpha, class 2A, member 2
chr1_-_16302608 0.16 ENST00000375743.4
ENST00000375733.2
ZBTB17
zinc finger and BTB domain containing 17
chr15_-_93199069 0.16 ENST00000327355.5
FAM174B
family with sequence similarity 174, member B
chr4_-_82393052 0.16 ENST00000335927.7
ENST00000504863.1
ENST00000264400.2
RASGEF1B
RasGEF domain family, member 1B
chr16_-_54962704 0.16 ENST00000502066.2
ENST00000560912.1
ENST00000558952.1
CRNDE
colorectal neoplasia differentially expressed (non-protein coding)
chr19_-_10946871 0.16 ENST00000589638.1
TMED1
transmembrane emp24 protein transport domain containing 1
chr15_-_43882140 0.16 ENST00000429176.1
PPIP5K1
diphosphoinositol pentakisphosphate kinase 1
chr15_-_83316254 0.16 ENST00000567678.1
ENST00000450751.2
CPEB1
cytoplasmic polyadenylation element binding protein 1
chr19_+_38879061 0.16 ENST00000587013.1
SPRED3
sprouty-related, EVH1 domain containing 3
chr12_+_70760056 0.16 ENST00000258111.4
KCNMB4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr17_-_72855989 0.15 ENST00000293190.5
GRIN2C
glutamate receptor, ionotropic, N-methyl D-aspartate 2C
chr9_-_14322319 0.15 ENST00000606230.1
NFIB
nuclear factor I/B
chr9_+_96928516 0.15 ENST00000602703.1
RP11-2B6.3
RP11-2B6.3
chr3_+_184279566 0.15 ENST00000330394.2
EPHB3
EPH receptor B3
chr13_+_98795664 0.15 ENST00000376581.5
FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr11_-_3663502 0.15 ENST00000359918.4
ART5
ADP-ribosyltransferase 5
chr20_+_49348081 0.15 ENST00000371610.2
PARD6B
par-6 family cell polarity regulator beta
chr2_+_220306238 0.15 ENST00000435853.1
SPEG
SPEG complex locus
chr1_+_39734131 0.15 ENST00000530262.1
MACF1
microtubule-actin crosslinking factor 1
chr19_+_39574945 0.15 ENST00000331256.5
PAPL
Iron/zinc purple acid phosphatase-like protein
chr6_-_33266687 0.15 ENST00000444031.2
RGL2
ral guanine nucleotide dissociation stimulator-like 2
chr19_-_36523529 0.15 ENST00000593074.1
CLIP3
CAP-GLY domain containing linker protein 3
chr7_-_27153454 0.15 ENST00000522456.1
HOXA3
homeobox A3
chr16_+_3070356 0.14 ENST00000341627.5
ENST00000575124.1
ENST00000575836.1
TNFRSF12A
tumor necrosis factor receptor superfamily, member 12A
chr16_-_402639 0.14 ENST00000262320.3
AXIN1
axin 1
chr19_-_52227221 0.14 ENST00000222115.1
ENST00000540069.2
HAS1
hyaluronan synthase 1
chr19_+_47778119 0.14 ENST00000552360.2
PRR24
proline rich 24
chr17_-_7137857 0.14 ENST00000005340.5
DVL2
dishevelled segment polarity protein 2
chr19_+_3572758 0.14 ENST00000416526.1
HMG20B
high mobility group 20B
chr16_+_57662596 0.14 ENST00000567397.1
ENST00000568979.1
GPR56
G protein-coupled receptor 56
chrX_-_48814278 0.14 ENST00000455452.1
OTUD5
OTU domain containing 5
chr22_+_36784632 0.14 ENST00000424761.1
RP4-633O19__A.1
RP4-633O19__A.1
chr10_-_129924611 0.14 ENST00000368654.3
MKI67
marker of proliferation Ki-67
chr10_-_13043697 0.14 ENST00000378825.3
CCDC3
coiled-coil domain containing 3
chr19_+_44037546 0.14 ENST00000601282.1
ZNF575
zinc finger protein 575
chr3_+_37903432 0.14 ENST00000443503.2
CTDSPL
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chrX_-_47509994 0.13 ENST00000343894.4
ELK1
ELK1, member of ETS oncogene family
chr7_+_86781916 0.13 ENST00000579592.1
ENST00000434534.1
DMTF1
cyclin D binding myb-like transcription factor 1
chr5_-_33892046 0.13 ENST00000352040.3
ADAMTS12
ADAM metallopeptidase with thrombospondin type 1 motif, 12
chr2_-_73460334 0.13 ENST00000258083.2
PRADC1
protease-associated domain containing 1
chr11_+_20044096 0.13 ENST00000533917.1
NAV2
neuron navigator 2
chr16_-_2264779 0.13 ENST00000333503.7
PGP
phosphoglycolate phosphatase
chr22_-_30722866 0.13 ENST00000403477.3
TBC1D10A
TBC1 domain family, member 10A
chr17_+_72772621 0.13 ENST00000335464.5
ENST00000417024.2
ENST00000578764.1
ENST00000582773.1
ENST00000582330.1
TMEM104
transmembrane protein 104
chr19_-_663147 0.13 ENST00000606702.1
RNF126
ring finger protein 126
chrX_-_128788914 0.13 ENST00000429967.1
ENST00000307484.6
APLN
apelin
chr7_-_100026280 0.13 ENST00000360951.4
ENST00000398027.2
ENST00000324725.6
ENST00000472716.1
ZCWPW1
zinc finger, CW type with PWWP domain 1
chr22_+_37956479 0.13 ENST00000430687.1
CDC42EP1
CDC42 effector protein (Rho GTPase binding) 1
chr14_-_69446034 0.13 ENST00000193403.6
ACTN1
actinin, alpha 1
chr20_+_34894247 0.13 ENST00000373913.3
DLGAP4
discs, large (Drosophila) homolog-associated protein 4
chrX_-_154033686 0.13 ENST00000453245.1
ENST00000428488.1
ENST00000369531.1
MPP1
membrane protein, palmitoylated 1, 55kDa
chr11_+_20044600 0.13 ENST00000311043.8
NAV2
neuron navigator 2
chr16_-_2185899 0.13 ENST00000262304.4
ENST00000423118.1
PKD1
polycystic kidney disease 1 (autosomal dominant)
chr4_-_36246060 0.13 ENST00000303965.4
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr9_+_35829208 0.13 ENST00000439587.2
ENST00000377991.4
TMEM8B
transmembrane protein 8B
chr15_+_76352178 0.13 ENST00000388942.3
C15orf27
chromosome 15 open reading frame 27
chr19_-_40724246 0.13 ENST00000311308.6
TTC9B
tetratricopeptide repeat domain 9B
chr19_+_45596398 0.13 ENST00000544069.2
PPP1R37
protein phosphatase 1, regulatory subunit 37
chr17_-_7137582 0.13 ENST00000575756.1
ENST00000575458.1
DVL2
dishevelled segment polarity protein 2
chr7_-_92463210 0.13 ENST00000265734.4
CDK6
cyclin-dependent kinase 6
chr11_+_86748998 0.12 ENST00000525018.1
ENST00000355734.4
TMEM135
transmembrane protein 135
chr19_-_38714847 0.12 ENST00000420980.2
ENST00000355526.4
DPF1
D4, zinc and double PHD fingers family 1
chr19_+_44037334 0.12 ENST00000314228.5
ZNF575
zinc finger protein 575
chr8_-_101734308 0.12 ENST00000519004.1
ENST00000519363.1
ENST00000520142.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chr19_-_46145696 0.12 ENST00000588172.1
EML2
echinoderm microtubule associated protein like 2
chrX_-_49056635 0.12 ENST00000472598.1
ENST00000538567.1
ENST00000479808.1
ENST00000263233.4
SYP
synaptophysin
chr3_-_52273098 0.12 ENST00000499914.2
ENST00000305533.5
ENST00000597542.1
TWF2
TLR9
twinfilin actin-binding protein 2
toll-like receptor 9
chr7_+_100770328 0.12 ENST00000223095.4
ENST00000445463.2
SERPINE1
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
chr1_-_85155939 0.12 ENST00000603677.1
SSX2IP
synovial sarcoma, X breakpoint 2 interacting protein
chr2_-_42721110 0.12 ENST00000394973.4
ENST00000306078.1
KCNG3
potassium voltage-gated channel, subfamily G, member 3
chr17_+_7155343 0.12 ENST00000573513.1
ENST00000354429.2
ENST00000574255.1
ENST00000396627.2
ENST00000356683.2
ELP5
elongator acetyltransferase complex subunit 5
chr2_-_32390801 0.12 ENST00000608489.1
RP11-563N4.1
RP11-563N4.1
chr5_+_172068232 0.12 ENST00000520919.1
ENST00000522853.1
ENST00000369800.5
NEURL1B
neuralized E3 ubiquitin protein ligase 1B
chr17_-_1928621 0.12 ENST00000331238.6
RTN4RL1
reticulon 4 receptor-like 1
chr6_-_33160231 0.12 ENST00000395194.1
ENST00000457788.1
ENST00000341947.2
ENST00000357486.1
ENST00000374714.1
ENST00000374713.1
ENST00000395197.1
ENST00000374712.1
ENST00000361917.1
ENST00000374708.4
COL11A2
collagen, type XI, alpha 2
chr11_+_20044375 0.12 ENST00000525322.1
ENST00000530408.1
NAV2
neuron navigator 2
chr19_+_47523058 0.12 ENST00000602212.1
ENST00000602189.1
NPAS1
neuronal PAS domain protein 1
chr15_+_39873268 0.12 ENST00000397591.2
ENST00000260356.5
THBS1
thrombospondin 1
chrX_+_155227246 0.12 ENST00000244174.5
ENST00000424344.3
IL9R
interleukin 9 receptor
chr19_+_39971505 0.12 ENST00000544017.1
TIMM50
translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
chr11_-_72492878 0.11 ENST00000535054.1
ENST00000545082.1
STARD10
StAR-related lipid transfer (START) domain containing 10
chr2_+_111878483 0.11 ENST00000308659.8
ENST00000357757.2
ENST00000393253.2
ENST00000337565.5
ENST00000393256.3
BCL2L11
BCL2-like 11 (apoptosis facilitator)
chr9_+_130890612 0.11 ENST00000443493.1
AL590708.2
AL590708.2
chr14_-_74417096 0.11 ENST00000286544.3
FAM161B
family with sequence similarity 161, member B
chr19_-_41196534 0.11 ENST00000252891.4
NUMBL
numb homolog (Drosophila)-like
chr10_-_43762329 0.11 ENST00000395810.1
RASGEF1A
RasGEF domain family, member 1A
chr17_-_46691990 0.11 ENST00000576562.1
HOXB8
homeobox B8
chr6_-_37665751 0.11 ENST00000297153.7
ENST00000434837.3
MDGA1
MAM domain containing glycosylphosphatidylinositol anchor 1
chr16_+_25703274 0.11 ENST00000331351.5
HS3ST4
heparan sulfate (glucosamine) 3-O-sulfotransferase 4
chr19_+_7968728 0.11 ENST00000397981.3
ENST00000545011.1
ENST00000397983.3
ENST00000397979.3
MAP2K7
mitogen-activated protein kinase kinase 7
chr19_-_46405861 0.11 ENST00000322217.5
MYPOP
Myb-related transcription factor, partner of profilin
chr15_-_64648273 0.11 ENST00000607537.1
ENST00000303052.7
ENST00000303032.6
CSNK1G1
casein kinase 1, gamma 1
chr14_-_75079294 0.11 ENST00000556359.1
LTBP2
latent transforming growth factor beta binding protein 2
chr11_-_73882249 0.11 ENST00000535954.1
C2CD3
C2 calcium-dependent domain containing 3
chr2_-_61108449 0.11 ENST00000439412.1
ENST00000452343.1
AC010733.4
AC010733.4
chr11_-_64545941 0.11 ENST00000377387.1
SF1
splicing factor 1
chrX_-_53350522 0.11 ENST00000396435.3
ENST00000375368.5
IQSEC2
IQ motif and Sec7 domain 2
chr14_+_77648167 0.11 ENST00000554346.1
ENST00000298351.4
TMEM63C
transmembrane protein 63C
chr13_+_49794474 0.11 ENST00000218721.1
ENST00000398307.1
MLNR
motilin receptor
chr17_-_72772462 0.11 ENST00000582870.1
ENST00000581136.1
ENST00000357814.3
ENST00000579218.1
ENST00000583476.1
ENST00000580301.1
ENST00000583757.1
ENST00000582524.1
NAT9
N-acetyltransferase 9 (GCN5-related, putative)
chr12_-_31479107 0.11 ENST00000542983.1
FAM60A
family with sequence similarity 60, member A
chr2_+_219433588 0.11 ENST00000295701.5
RQCD1
RCD1 required for cell differentiation1 homolog (S. pombe)
chr3_+_88108381 0.11 ENST00000473136.1
RP11-159G9.5
Uncharacterized protein
chr17_-_72869086 0.11 ENST00000581530.1
ENST00000420580.2
ENST00000455107.2
ENST00000413947.2
ENST00000581219.1
ENST00000582944.1
FDXR
ferredoxin reductase
chr1_-_147142557 0.11 ENST00000369238.6
ACP6
acid phosphatase 6, lysophosphatidic
chr15_-_43882353 0.11 ENST00000453080.1
ENST00000360301.4
ENST00000360135.4
ENST00000417085.1
ENST00000431962.1
ENST00000334933.4
ENST00000381879.4
ENST00000420765.1
PPIP5K1
diphosphoinositol pentakisphosphate kinase 1
chr16_-_67969888 0.11 ENST00000574576.2
PSMB10
proteasome (prosome, macropain) subunit, beta type, 10
chr19_-_36523709 0.11 ENST00000592017.1
ENST00000360535.4
CLIP3
CAP-GLY domain containing linker protein 3
chr6_-_33266492 0.11 ENST00000425946.1
RGL2
ral guanine nucleotide dissociation stimulator-like 2
chr8_+_55370487 0.11 ENST00000297316.4
SOX17
SRY (sex determining region Y)-box 17
chrX_+_51075658 0.10 ENST00000356450.2
NUDT10
nudix (nucleoside diphosphate linked moiety X)-type motif 10
chr16_-_74808710 0.10 ENST00000219368.3
ENST00000544337.1
FA2H
fatty acid 2-hydroxylase
chr17_+_7155556 0.10 ENST00000570500.1
ENST00000574993.1
ENST00000396628.2
ENST00000573657.1
ELP5
elongator acetyltransferase complex subunit 5
chr3_-_171177852 0.10 ENST00000284483.8
ENST00000475336.1
ENST00000357327.5
ENST00000460047.1
ENST00000488470.1
ENST00000470834.1
TNIK
TRAF2 and NCK interacting kinase
chr19_-_49568311 0.10 ENST00000595857.1
ENST00000451356.2
NTF4
neurotrophin 4
chr2_+_97426631 0.10 ENST00000377075.2
CNNM4
cyclin M4
chrX_-_154033793 0.10 ENST00000369534.3
ENST00000413259.3
MPP1
membrane protein, palmitoylated 1, 55kDa

Network of associatons between targets according to the STRING database.

First level regulatory network of EGR3_EGR2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0010160 sensory organ boundary specification(GO:0008052) formation of organ boundary(GO:0010160) taste bud development(GO:0061193)
0.1 0.4 GO:0042040 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.1 0.4 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.5 GO:0051585 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.1 0.7 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.1 0.5 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422)
0.1 0.3 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.1 0.2 GO:2001112 negative regulation of hepatocyte growth factor receptor signaling pathway(GO:1902203) regulation of cellular response to hepatocyte growth factor stimulus(GO:2001112) negative regulation of cellular response to hepatocyte growth factor stimulus(GO:2001113)
0.1 0.2 GO:1901207 regulation of heart looping(GO:1901207)
0.1 0.2 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.1 0.3 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.1 0.6 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 0.1 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.1 0.2 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.1 0.6 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.1 0.5 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.1 0.2 GO:0033058 directional locomotion(GO:0033058)
0.0 0.1 GO:0048320 axial mesoderm formation(GO:0048320)
0.0 0.3 GO:0021997 neural plate axis specification(GO:0021997)
0.0 0.3 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.4 GO:0021564 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025) vagus nerve development(GO:0021564)
0.0 0.2 GO:0018057 peptidyl-lysine oxidation(GO:0018057) negative regulation of T-helper 17 cell lineage commitment(GO:2000329)
0.0 0.1 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.0 0.1 GO:1901895 negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.0 0.1 GO:0001300 chronological cell aging(GO:0001300)
0.0 0.2 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.7 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:0002605 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) negative regulation of dendritic cell antigen processing and presentation(GO:0002605) negative regulation of endothelial cell chemotaxis(GO:2001027)
0.0 0.1 GO:0060139 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139) apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.0 0.3 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.0 0.1 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.0 0.1 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.0 0.1 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.0 0.1 GO:0072287 metanephric distal tubule morphogenesis(GO:0072287)
0.0 0.1 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.0 0.3 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.3 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.3 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.1 GO:0046626 regulation of insulin receptor signaling pathway(GO:0046626) regulation of cellular response to insulin stimulus(GO:1900076)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.2 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.0 0.2 GO:0061188 negative regulation of chromatin silencing at rDNA(GO:0061188)
0.0 0.1 GO:1903461 Okazaki fragment processing involved in mitotic DNA replication(GO:1903461)
0.0 0.1 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.0 0.1 GO:0070846 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.0 0.1 GO:0016334 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.0 0.1 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 0.1 GO:1904719 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.0 0.1 GO:0006423 cysteinyl-tRNA aminoacylation(GO:0006423)
0.0 0.1 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.0 0.1 GO:0060381 regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381)
0.0 0.2 GO:0071104 response to interleukin-9(GO:0071104)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.1 GO:0060623 pericentric heterochromatin assembly(GO:0031508) regulation of chromosome condensation(GO:0060623)
0.0 0.3 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.1 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.0 0.1 GO:0060031 mediolateral intercalation(GO:0060031) planar cell polarity pathway involved in gastrula mediolateral intercalation(GO:0060775)
0.0 0.3 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0 0.1 GO:1902824 cleavage furrow ingression(GO:0036090) positive regulation of late endosome to lysosome transport(GO:1902824)
0.0 0.2 GO:0097473 cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.0 0.1 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.1 GO:0003335 corneocyte development(GO:0003335)
0.0 0.1 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 0.1 GO:0008286 insulin receptor signaling pathway(GO:0008286)
0.0 0.1 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.0 0.1 GO:0071529 cementum mineralization(GO:0071529)
0.0 0.1 GO:0072299 posterior mesonephric tubule development(GO:0072166) negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.0 0.0 GO:1990535 neuron projection maintenance(GO:1990535)
0.0 0.1 GO:0061074 regulation of neural retina development(GO:0061074)
0.0 0.1 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.0 0.1 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.0 0.2 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.1 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.0 0.1 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.1 GO:0044691 tooth eruption(GO:0044691)
0.0 0.1 GO:0040009 regulation of growth rate(GO:0040009)
0.0 0.3 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.5 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.2 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.1 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.0 0.2 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.1 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.0 0.3 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.1 GO:0060017 specification of organ position(GO:0010159) parathyroid gland development(GO:0060017)
0.0 0.1 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.1 GO:0090108 positive regulation of high-density lipoprotein particle assembly(GO:0090108) positive regulation of secretion of lysosomal enzymes(GO:0090340)
0.0 0.1 GO:2001302 lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
0.0 0.1 GO:0043308 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil activation(GO:0043307) eosinophil degranulation(GO:0043308)
0.0 0.1 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.0 0.1 GO:0015961 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.1 GO:0021551 central nervous system morphogenesis(GO:0021551) forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.1 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0 0.1 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.1 GO:0071926 endocannabinoid signaling pathway(GO:0071926)
0.0 0.1 GO:0043449 cellular alkene metabolic process(GO:0043449)
0.0 0.2 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.1 GO:1902164 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0 0.2 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.0 GO:0071629 cytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071629)
0.0 0.2 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.1 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.0 0.1 GO:2000691 regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.0 0.1 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.0 0.4 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.0 GO:0043634 polyadenylation-dependent RNA catabolic process(GO:0043633) polyadenylation-dependent ncRNA catabolic process(GO:0043634)
0.0 0.0 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.0 0.1 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.0 0.0 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.0 0.1 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.0 0.0 GO:0042732 D-xylose metabolic process(GO:0042732)
0.0 0.1 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.0 0.1 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.0 0.1 GO:0090650 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0 0.0 GO:0051604 protein maturation(GO:0051604)
0.0 0.3 GO:0003323 type B pancreatic cell development(GO:0003323)
0.0 0.0 GO:1990051 activation of protein kinase C activity(GO:1990051)
0.0 0.1 GO:1902361 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.0 0.2 GO:1901342 regulation of vasculature development(GO:1901342)
0.0 0.0 GO:0033386 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.0 0.1 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.4 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.1 GO:0009137 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.0 0.0 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.0 0.1 GO:0072553 terminal button organization(GO:0072553)
0.0 0.1 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.0 0.1 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.0 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.1 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.0 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.0 0.1 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.0 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
0.0 0.2 GO:0015866 ADP transport(GO:0015866)
0.0 0.1 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 0.1 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.0 0.1 GO:0032782 bile acid secretion(GO:0032782)
0.0 0.1 GO:0006172 ADP biosynthetic process(GO:0006172)
0.0 0.1 GO:1902564 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of neutrophil activation(GO:1902564)
0.0 0.0 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.0 0.3 GO:0009812 flavonoid metabolic process(GO:0009812)
0.0 0.1 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.2 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.1 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 0.0 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.0 0.1 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.0 0.0 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.0 0.2 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.0 GO:1901671 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874) positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925) positive regulation of translational initiation by iron(GO:0045994) positive regulation of superoxide dismutase activity(GO:1901671) positive regulation of removal of superoxide radicals(GO:1904833)
0.0 0.1 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.4 GO:0003299 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.0 0.0 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 0.3 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.1 0.6 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.6 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.4 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.2 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 0.1 GO:0002133 polycystin complex(GO:0002133)
0.0 0.1 GO:0071664 beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664)
0.0 0.0 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.1 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.0 0.1 GO:0000806 Y chromosome(GO:0000806)
0.0 0.2 GO:0031201 SNARE complex(GO:0031201)
0.0 0.2 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 0.1 GO:0042643 actomyosin, actin portion(GO:0042643)
0.0 0.3 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 0.3 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.4 GO:0005916 fascia adherens(GO:0005916)
0.0 0.1 GO:0098855 HCN channel complex(GO:0098855)
0.0 0.1 GO:0000799 nuclear condensin complex(GO:0000799)
0.0 0.4 GO:0005845 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.1 GO:0000801 central element(GO:0000801)
0.0 0.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0033503 HULC complex(GO:0033503)
0.0 0.3 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.5 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.1 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.1 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 0.1 GO:0097443 sorting endosome(GO:0097443)
0.0 0.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.0 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.1 0.6 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.1 0.5 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 0.5 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 0.3 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.1 0.2 GO:0017130 poly(C) RNA binding(GO:0017130)
0.1 0.2 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.1 0.2 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.1 0.3 GO:0043208 glycosphingolipid binding(GO:0043208) ceramide binding(GO:0097001)
0.0 0.7 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.6 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.3 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.0 0.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.0 GO:0016866 intramolecular transferase activity(GO:0016866)
0.0 0.2 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.3 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 0.1 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.1 GO:0004324 ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
0.0 0.2 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.1 GO:0052642 lysophosphatidic acid phosphatase activity(GO:0052642)
0.0 0.1 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.0 0.1 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.0 0.3 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.1 GO:0070546 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 0.1 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.2 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.1 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
0.0 0.2 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.1 GO:0017089 glycolipid transporter activity(GO:0017089)
0.0 0.0 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.1 GO:0004817 cysteine-tRNA ligase activity(GO:0004817)
0.0 0.1 GO:0003978 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.2 GO:0047820 D-glutamate cyclase activity(GO:0047820)
0.0 0.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.1 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.1 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.2 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.1 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.0 0.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.3 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.7 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0001133 RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding(GO:0001133)
0.0 0.1 GO:0047977 linoleate 13S-lipoxygenase activity(GO:0016165) hepoxilin-epoxide hydrolase activity(GO:0047977)
0.0 0.1 GO:0052841 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.1 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.0 0.1 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.1 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.4 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.3 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.0 0.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.1 GO:0005115 receptor tyrosine kinase-like orphan receptor binding(GO:0005115) chemoattractant activity involved in axon guidance(GO:1902379)
0.0 0.5 GO:0017166 vinculin binding(GO:0017166)
0.0 0.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.2 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.2 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.1 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.0 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.0 0.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.1 GO:0005119 smoothened binding(GO:0005119)
0.0 0.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.1 REACTOME SIGNALING BY NOTCH2 Genes involved in Signaling by NOTCH2
0.0 0.4 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.5 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen