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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for EGR1_EGR4

Z-value: 0.99

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Transcription factors associated with EGR1_EGR4

Gene Symbol Gene ID Gene Info
EGR1
ENSG00000120738.7 early growth response 1
EGR4
ENSG00000135625.6 early growth response 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EGR1hg19_v2_chr5_+_137801160_1378011790.777.2e-02Click!
EGR4hg19_v2_chr2_-_73520667_73520833-0.335.3e-01Click!

Activity profile of EGR1_EGR4 motif

Sorted Z-values of EGR1_EGR4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_12012170 1.23 ENST00000487103.1
HIVEP1
human immunodeficiency virus type I enhancer binding protein 1
chr15_-_80263506 0.81 ENST00000335661.6
BCL2A1
BCL2-related protein A1
chr8_-_145060593 0.79 ENST00000313059.5
ENST00000524918.1
ENST00000313028.7
ENST00000525773.1
PARP10
poly (ADP-ribose) polymerase family, member 10
chr10_+_49514698 0.76 ENST00000432379.1
ENST00000429041.1
ENST00000374189.1
MAPK8
mitogen-activated protein kinase 8
chr15_+_52311398 0.71 ENST00000261845.5
MAPK6
mitogen-activated protein kinase 6
chr2_+_187350883 0.68 ENST00000337859.6
ZC3H15
zinc finger CCCH-type containing 15
chr2_+_220306745 0.64 ENST00000431523.1
ENST00000396698.1
ENST00000396695.2
SPEG
SPEG complex locus
chr1_+_65886326 0.62 ENST00000371059.3
ENST00000371060.3
ENST00000349533.6
ENST00000406510.3
LEPR
leptin receptor
chr3_-_88108192 0.60 ENST00000309534.6
CGGBP1
CGG triplet repeat binding protein 1
chr4_+_17579110 0.57 ENST00000606142.1
LAP3
leucine aminopeptidase 3
chr1_+_65886244 0.57 ENST00000344610.8
LEPR
leptin receptor
chr7_-_44365020 0.57 ENST00000395747.2
ENST00000347193.4
ENST00000346990.4
ENST00000258682.6
ENST00000353625.4
ENST00000421607.1
ENST00000424197.1
ENST00000502837.2
ENST00000350811.3
ENST00000395749.2
CAMK2B
calcium/calmodulin-dependent protein kinase II beta
chr19_-_49371711 0.54 ENST00000355496.5
ENST00000263265.6
PLEKHA4
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4
chrX_-_108976521 0.53 ENST00000469796.2
ENST00000502391.1
ENST00000508092.1
ENST00000340800.2
ENST00000348502.6
ACSL4
acyl-CoA synthetase long-chain family member 4
chr18_+_22006646 0.52 ENST00000585067.1
ENST00000578221.1
IMPACT
impact RWD domain protein
chr3_-_135915401 0.52 ENST00000491050.1
MSL2
male-specific lethal 2 homolog (Drosophila)
chr6_+_99282570 0.52 ENST00000328345.5
POU3F2
POU class 3 homeobox 2
chr2_-_148778323 0.52 ENST00000440042.1
ENST00000535373.1
ENST00000540442.1
ENST00000536575.1
ORC4
origin recognition complex, subunit 4
chr7_-_127032363 0.51 ENST00000393312.1
ZNF800
zinc finger protein 800
chr2_+_191513959 0.50 ENST00000337386.5
ENST00000357215.5
NAB1
NGFI-A binding protein 1 (EGR1 binding protein 1)
chr19_-_49622348 0.49 ENST00000408991.2
C19orf73
chromosome 19 open reading frame 73
chr13_+_41635617 0.47 ENST00000542082.1
WBP4
WW domain binding protein 4
chr2_+_187350973 0.46 ENST00000544130.1
ZC3H15
zinc finger CCCH-type containing 15
chr16_+_75182376 0.46 ENST00000570010.1
ENST00000568079.1
ENST00000464850.1
ENST00000332307.4
ENST00000393430.2
ZFP1
ZFP1 zinc finger protein
chr12_-_96794330 0.45 ENST00000261211.3
CDK17
cyclin-dependent kinase 17
chr8_+_26149274 0.44 ENST00000522535.1
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr18_+_22006580 0.43 ENST00000284202.4
IMPACT
impact RWD domain protein
chr21_+_17102311 0.43 ENST00000285679.6
ENST00000351097.5
ENST00000285681.2
ENST00000400183.2
USP25
ubiquitin specific peptidase 25
chr1_-_197744763 0.42 ENST00000422998.1
DENND1B
DENN/MADD domain containing 1B
chr9_-_15510989 0.41 ENST00000380715.1
ENST00000380716.4
ENST00000380738.4
ENST00000380733.4
PSIP1
PC4 and SFRS1 interacting protein 1
chr19_+_55795493 0.41 ENST00000309383.1
BRSK1
BR serine/threonine kinase 1
chr4_+_184427235 0.41 ENST00000412117.1
ENST00000434682.2
ING2
inhibitor of growth family, member 2
chr1_-_63153944 0.41 ENST00000340370.5
ENST00000404627.2
ENST00000251157.5
DOCK7
dedicator of cytokinesis 7
chr9_+_129987488 0.40 ENST00000446764.1
GARNL3
GTPase activating Rap/RanGAP domain-like 3
chr12_+_77158021 0.40 ENST00000550876.1
ZDHHC17
zinc finger, DHHC-type containing 17
chr1_-_9189144 0.40 ENST00000414642.2
GPR157
G protein-coupled receptor 157
chr1_+_6845497 0.39 ENST00000473578.1
ENST00000557126.1
CAMTA1
calmodulin binding transcription activator 1
chr4_+_17578815 0.39 ENST00000226299.4
LAP3
leucine aminopeptidase 3
chr17_-_15466742 0.39 ENST00000584811.1
ENST00000419890.2
TVP23C
trans-golgi network vesicle protein 23 homolog C (S. cerevisiae)
chr5_+_61602236 0.38 ENST00000514082.1
ENST00000407818.3
KIF2A
kinesin heavy chain member 2A
chr1_+_155051379 0.38 ENST00000418360.2
EFNA3
ephrin-A3
chr2_-_219433014 0.38 ENST00000418019.1
ENST00000454775.1
ENST00000338465.5
ENST00000415516.1
ENST00000258399.3
USP37
ubiquitin specific peptidase 37
chr5_-_145214893 0.38 ENST00000394450.2
PRELID2
PRELI domain containing 2
chr4_+_76649797 0.38 ENST00000538159.1
ENST00000514213.2
USO1
USO1 vesicle transport factor
chr2_+_191513789 0.37 ENST00000409581.1
NAB1
NGFI-A binding protein 1 (EGR1 binding protein 1)
chr2_-_148778258 0.37 ENST00000392857.5
ENST00000457954.1
ENST00000392858.1
ENST00000542387.1
ORC4
origin recognition complex, subunit 4
chr9_+_96928516 0.37 ENST00000602703.1
RP11-2B6.3
RP11-2B6.3
chr1_-_166136187 0.37 ENST00000338353.3
FAM78B
family with sequence similarity 78, member B
chr9_-_86432547 0.37 ENST00000376365.3
ENST00000376371.2
GKAP1
G kinase anchoring protein 1
chr1_+_6845384 0.36 ENST00000303635.7
CAMTA1
calmodulin binding transcription activator 1
chr1_-_93426998 0.36 ENST00000370310.4
FAM69A
family with sequence similarity 69, member A
chr3_-_135916073 0.36 ENST00000481989.1
MSL2
male-specific lethal 2 homolog (Drosophila)
chr16_+_23847339 0.36 ENST00000303531.7
PRKCB
protein kinase C, beta
chr1_+_6845578 0.36 ENST00000467404.2
ENST00000439411.2
CAMTA1
calmodulin binding transcription activator 1
chr5_+_94982435 0.35 ENST00000511684.1
ENST00000380005.4
RFESD
Rieske (Fe-S) domain containing
chr11_-_65363259 0.35 ENST00000342202.4
KCNK7
potassium channel, subfamily K, member 7
chr14_-_45603657 0.35 ENST00000396062.3
FKBP3
FK506 binding protein 3, 25kDa
chr3_-_135915146 0.35 ENST00000473093.1
MSL2
male-specific lethal 2 homolog (Drosophila)
chr15_+_72410629 0.34 ENST00000340912.4
ENST00000544171.1
SENP8
SUMO/sentrin specific peptidase family member 8
chr1_-_111506562 0.34 ENST00000485275.2
ENST00000369763.4
LRIF1
ligand dependent nuclear receptor interacting factor 1
chr6_+_134274354 0.34 ENST00000367869.1
TBPL1
TBP-like 1
chr16_+_23847355 0.34 ENST00000498058.1
PRKCB
protein kinase C, beta
chr13_-_52027134 0.34 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
INTS6
integrator complex subunit 6
chr6_+_138188351 0.33 ENST00000421450.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr14_-_102553371 0.33 ENST00000553585.1
ENST00000216281.8
HSP90AA1
heat shock protein 90kDa alpha (cytosolic), class A member 1
chr11_-_64512273 0.33 ENST00000377497.3
ENST00000377487.1
ENST00000430645.1
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr17_-_4269768 0.33 ENST00000396981.2
UBE2G1
ubiquitin-conjugating enzyme E2G 1
chr6_+_134274322 0.33 ENST00000367871.1
ENST00000237264.4
TBPL1
TBP-like 1
chr2_-_98612379 0.32 ENST00000425805.2
TMEM131
transmembrane protein 131
chr1_-_154600421 0.32 ENST00000368471.3
ENST00000292205.5
ADAR
adenosine deaminase, RNA-specific
chr12_-_46385811 0.31 ENST00000419565.2
SCAF11
SR-related CTD-associated factor 11
chr11_+_95523621 0.31 ENST00000325542.5
ENST00000325486.5
ENST00000544522.1
ENST00000541365.1
CEP57
centrosomal protein 57kDa
chr10_+_27444268 0.31 ENST00000375940.4
ENST00000342386.6
MASTL
microtubule associated serine/threonine kinase-like
chr2_+_149402009 0.31 ENST00000457184.1
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr21_+_38445539 0.31 ENST00000418766.1
ENST00000450533.1
ENST00000438055.1
ENST00000355666.1
ENST00000540756.1
ENST00000399010.1
TTC3
tetratricopeptide repeat domain 3
chr2_+_191513587 0.31 ENST00000416973.1
ENST00000426601.1
NAB1
NGFI-A binding protein 1 (EGR1 binding protein 1)
chr14_+_45553296 0.30 ENST00000355765.6
ENST00000553605.1
PRPF39
pre-mRNA processing factor 39
chr13_-_45915221 0.30 ENST00000309246.5
ENST00000379060.4
ENST00000379055.1
ENST00000527226.1
ENST00000379056.1
TPT1
tumor protein, translationally-controlled 1
chr11_+_124609823 0.30 ENST00000412681.2
NRGN
neurogranin (protein kinase C substrate, RC3)
chr11_-_46142615 0.30 ENST00000529734.1
ENST00000323180.6
PHF21A
PHD finger protein 21A
chr4_+_57774042 0.30 ENST00000309042.7
REST
RE1-silencing transcription factor
chr6_+_64282447 0.30 ENST00000370650.2
ENST00000578299.1
PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr9_+_131451480 0.30 ENST00000322030.8
SET
SET nuclear oncogene
chr21_+_37692481 0.30 ENST00000400485.1
MORC3
MORC family CW-type zinc finger 3
chr18_-_812231 0.29 ENST00000314574.4
YES1
v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
chr15_-_34502197 0.29 ENST00000557877.1
KATNBL1
katanin p80 subunit B-like 1
chr11_+_95523823 0.29 ENST00000538658.1
CEP57
centrosomal protein 57kDa
chr14_-_51027838 0.29 ENST00000555216.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr1_-_85156417 0.28 ENST00000422026.1
SSX2IP
synovial sarcoma, X breakpoint 2 interacting protein
chr5_+_145583156 0.28 ENST00000265271.5
RBM27
RNA binding motif protein 27
chr3_-_88108212 0.28 ENST00000482016.1
CGGBP1
CGG triplet repeat binding protein 1
chr7_-_100493744 0.28 ENST00000428317.1
ENST00000441605.1
ACHE
acetylcholinesterase (Yt blood group)
chr9_-_124976185 0.28 ENST00000464484.2
LHX6
LIM homeobox 6
chr11_+_114310237 0.28 ENST00000539119.1
REXO2
RNA exonuclease 2
chr11_-_64512469 0.28 ENST00000377485.1
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr10_-_112678692 0.28 ENST00000605742.1
BBIP1
BBSome interacting protein 1
chr17_-_36413133 0.27 ENST00000523089.1
ENST00000312412.4
ENST00000520237.1
RP11-1407O15.2
TBC1 domain family member 3
chr1_+_35734562 0.27 ENST00000314607.6
ENST00000373297.2
ZMYM4
zinc finger, MYM-type 4
chr2_-_38829768 0.27 ENST00000378915.3
HNRNPLL
heterogeneous nuclear ribonucleoprotein L-like
chr7_-_100493482 0.27 ENST00000411582.1
ENST00000419336.2
ENST00000241069.5
ENST00000302913.4
ACHE
acetylcholinesterase (Yt blood group)
chrX_-_108976410 0.27 ENST00000504980.1
ACSL4
acyl-CoA synthetase long-chain family member 4
chr5_-_115177247 0.27 ENST00000500945.2
ATG12
autophagy related 12
chr9_+_19230433 0.27 ENST00000434457.2
ENST00000602925.1
DENND4C
DENN/MADD domain containing 4C
chr1_-_166135952 0.27 ENST00000354422.3
FAM78B
family with sequence similarity 78, member B
chr6_-_4135825 0.27 ENST00000380118.3
ENST00000413766.2
ENST00000361538.2
ECI2
enoyl-CoA delta isomerase 2
chr8_-_74791051 0.27 ENST00000453587.2
ENST00000602969.1
ENST00000602593.1
ENST00000419880.3
ENST00000517608.1
UBE2W
ubiquitin-conjugating enzyme E2W (putative)
chr17_-_73179046 0.27 ENST00000314523.7
ENST00000420826.2
SUMO2
small ubiquitin-like modifier 2
chr17_+_11924129 0.27 ENST00000353533.5
ENST00000415385.3
MAP2K4
mitogen-activated protein kinase kinase 4
chr10_-_95462265 0.26 ENST00000536233.1
ENST00000359204.4
ENST00000371430.2
ENST00000394100.2
FRA10AC1
fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1
chr8_-_63951730 0.26 ENST00000260118.6
GGH
gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
chr3_+_113667354 0.26 ENST00000491556.1
ZDHHC23
zinc finger, DHHC-type containing 23
chr12_+_130822606 0.26 ENST00000546060.1
ENST00000539400.1
PIWIL1
piwi-like RNA-mediated gene silencing 1
chr12_+_95867919 0.26 ENST00000261220.9
ENST00000549502.1
ENST00000553151.1
ENST00000550777.1
ENST00000551840.1
METAP2
methionyl aminopeptidase 2
chr6_-_137540477 0.26 ENST00000367735.2
ENST00000367739.4
ENST00000458076.1
ENST00000414770.1
IFNGR1
interferon gamma receptor 1
chr14_-_53619816 0.26 ENST00000323669.5
ENST00000395606.1
ENST00000357758.3
DDHD1
DDHD domain containing 1
chr13_-_52026730 0.26 ENST00000420668.2
INTS6
integrator complex subunit 6
chr18_-_812517 0.26 ENST00000584307.1
YES1
v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1
chr13_-_31039375 0.26 ENST00000399494.1
HMGB1
high mobility group box 1
chr16_+_3014217 0.25 ENST00000572045.1
KREMEN2
kringle containing transmembrane protein 2
chr17_-_73178599 0.25 ENST00000578238.1
SUMO2
small ubiquitin-like modifier 2
chr7_-_105925367 0.25 ENST00000354289.4
NAMPT
nicotinamide phosphoribosyltransferase
chr7_+_26241310 0.25 ENST00000396386.2
CBX3
chromobox homolog 3
chr19_-_36870087 0.25 ENST00000270001.7
ZFP14
ZFP14 zinc finger protein
chr5_-_142784101 0.25 ENST00000503201.1
ENST00000502892.1
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr1_-_86861660 0.25 ENST00000486215.1
ODF2L
outer dense fiber of sperm tails 2-like
chr12_+_105501487 0.25 ENST00000332180.5
KIAA1033
KIAA1033
chr19_-_13617037 0.25 ENST00000360228.5
CACNA1A
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
chr22_-_29137771 0.25 ENST00000439200.1
ENST00000405598.1
ENST00000398017.2
ENST00000425190.2
ENST00000348295.3
ENST00000382578.1
ENST00000382565.1
ENST00000382566.1
ENST00000382580.2
ENST00000328354.6
CHEK2
checkpoint kinase 2
chr5_+_145583107 0.25 ENST00000506502.1
RBM27
RNA binding motif protein 27
chr5_-_38556728 0.25 ENST00000506990.1
ENST00000453190.2
LIFR
leukemia inhibitory factor receptor alpha
chr2_+_61108650 0.24 ENST00000295025.8
REL
v-rel avian reticuloendotheliosis viral oncogene homolog
chr9_+_114659046 0.24 ENST00000374279.3
UGCG
UDP-glucose ceramide glucosyltransferase
chr4_-_103748696 0.24 ENST00000321805.7
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr5_-_137878887 0.24 ENST00000507939.1
ENST00000572514.1
ENST00000499810.2
ENST00000360541.5
ETF1
eukaryotic translation termination factor 1
chr5_+_61601965 0.24 ENST00000401507.3
KIF2A
kinesin heavy chain member 2A
chr4_-_78740511 0.24 ENST00000504123.1
ENST00000264903.4
ENST00000515441.1
CNOT6L
CCR4-NOT transcription complex, subunit 6-like
chr11_-_627143 0.24 ENST00000176195.3
SCT
secretin
chr4_+_184426147 0.24 ENST00000302327.3
ING2
inhibitor of growth family, member 2
chr9_-_15510287 0.24 ENST00000397519.2
PSIP1
PC4 and SFRS1 interacting protein 1
chr11_-_96123022 0.24 ENST00000542662.1
CCDC82
coiled-coil domain containing 82
chr15_-_66084428 0.23 ENST00000443035.3
ENST00000431932.2
DENND4A
DENN/MADD domain containing 4A
chr7_+_116593953 0.23 ENST00000397750.3
ST7-OT4
ST7 overlapping transcript 4
chr1_-_85156216 0.23 ENST00000342203.3
ENST00000370612.4
SSX2IP
synovial sarcoma, X breakpoint 2 interacting protein
chr22_+_46546406 0.23 ENST00000440343.1
ENST00000415785.1
PPARA
peroxisome proliferator-activated receptor alpha
chr1_-_85156090 0.23 ENST00000605755.1
ENST00000437941.2
SSX2IP
synovial sarcoma, X breakpoint 2 interacting protein
chr3_+_170075436 0.23 ENST00000476188.1
ENST00000259119.4
ENST00000426052.2
SKIL
SKI-like oncogene
chr1_-_23694794 0.23 ENST00000374608.3
ZNF436
zinc finger protein 436
chr7_+_33169142 0.23 ENST00000242067.6
ENST00000350941.3
ENST00000396127.2
ENST00000355070.2
ENST00000354265.4
ENST00000425508.2
BBS9
Bardet-Biedl syndrome 9
chr5_+_94982558 0.22 ENST00000311364.4
ENST00000458310.1
RFESD
Rieske (Fe-S) domain containing
chr4_+_120133791 0.22 ENST00000274030.6
USP53
ubiquitin specific peptidase 53
chr8_-_124408652 0.22 ENST00000287394.5
ATAD2
ATPase family, AAA domain containing 2
chr22_+_29138013 0.22 ENST00000216027.3
ENST00000398941.2
HSCB
HscB mitochondrial iron-sulfur cluster co-chaperone
chr19_+_49617609 0.22 ENST00000221459.2
ENST00000486217.2
LIN7B
lin-7 homolog B (C. elegans)
chr14_+_96342729 0.22 ENST00000504119.1
LINC00617
long intergenic non-protein coding RNA 617
chr9_-_103115135 0.22 ENST00000537512.1
TEX10
testis expressed 10
chr2_+_202316392 0.22 ENST00000194530.3
ENST00000392249.2
STRADB
STE20-related kinase adaptor beta
chr17_-_15466850 0.22 ENST00000438826.3
ENST00000225576.3
ENST00000519970.1
ENST00000518321.1
ENST00000428082.2
ENST00000522212.2
TVP23C
TVP23C-CDRT4
trans-golgi network vesicle protein 23 homolog C (S. cerevisiae)
TVP23C-CDRT4 readthrough
chr20_+_21284416 0.22 ENST00000539513.1
XRN2
5'-3' exoribonuclease 2
chr12_-_90102594 0.22 ENST00000428670.3
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr1_-_117113596 0.22 ENST00000457047.2
ENST00000369489.5
ENST00000369487.3
CD58
CD58 molecule
chr4_-_83351294 0.22 ENST00000502762.1
HNRNPDL
heterogeneous nuclear ribonucleoprotein D-like
chr2_+_42396574 0.22 ENST00000401738.3
EML4
echinoderm microtubule associated protein like 4
chr5_+_172484377 0.22 ENST00000523161.1
CREBRF
CREB3 regulatory factor
chr16_+_23847267 0.22 ENST00000321728.7
PRKCB
protein kinase C, beta
chr10_-_32217717 0.22 ENST00000396144.4
ENST00000375245.4
ENST00000344936.2
ENST00000375250.5
ARHGAP12
Rho GTPase activating protein 12
chr7_+_151038785 0.22 ENST00000413040.2
ENST00000568733.1
NUB1
negative regulator of ubiquitin-like proteins 1
chr2_+_86116396 0.22 ENST00000455121.3
AC105053.4
AC105053.4
chr7_-_16685422 0.22 ENST00000306999.2
ANKMY2
ankyrin repeat and MYND domain containing 2
chr17_-_56609302 0.21 ENST00000581607.1
ENST00000317256.6
ENST00000426861.1
ENST00000580809.1
ENST00000577729.1
ENST00000583291.1
SEPT4
septin 4
chr9_+_72873837 0.21 ENST00000361138.5
SMC5
structural maintenance of chromosomes 5
chr13_-_27745936 0.21 ENST00000282344.6
USP12
ubiquitin specific peptidase 12
chr2_+_64068074 0.21 ENST00000394417.2
ENST00000484142.1
ENST00000482668.1
ENST00000467648.2
UGP2
UDP-glucose pyrophosphorylase 2
chr7_+_26241325 0.21 ENST00000456948.1
ENST00000409747.1
CBX3
chromobox homolog 3
chr2_+_99758161 0.21 ENST00000409684.1
C2ORF15
Uncharacterized protein C2orf15
chr11_-_110167331 0.21 ENST00000534683.1
RDX
radixin
chr1_-_202129704 0.21 ENST00000476061.1
ENST00000544762.1
ENST00000467283.1
ENST00000464870.1
ENST00000435759.2
ENST00000486116.1
ENST00000543735.1
ENST00000308986.5
ENST00000477625.1
PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr11_-_102323489 0.21 ENST00000361236.3
TMEM123
transmembrane protein 123
chr2_-_174828892 0.20 ENST00000418194.2
SP3
Sp3 transcription factor
chr21_-_16437126 0.20 ENST00000318948.4
NRIP1
nuclear receptor interacting protein 1
chr9_+_116172958 0.20 ENST00000374165.1
C9orf43
chromosome 9 open reading frame 43
chr2_-_98612350 0.20 ENST00000186436.5
TMEM131
transmembrane protein 131
chrX_-_135056106 0.20 ENST00000433339.2
MMGT1
membrane magnesium transporter 1
chrX_-_128657457 0.20 ENST00000371121.3
ENST00000371123.1
ENST00000371122.4
SMARCA1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr8_+_30013875 0.20 ENST00000520829.1
DCTN6
dynactin 6
chr14_-_55493763 0.20 ENST00000455555.1
ENST00000360586.3
ENST00000421192.1
ENST00000420358.2
WDHD1
WD repeat and HMG-box DNA binding protein 1
chr22_+_27053567 0.20 ENST00000449717.1
ENST00000453023.1
MIAT
myocardial infarction associated transcript (non-protein coding)
chr2_+_122494676 0.20 ENST00000455432.1
TSN
translin
chr5_+_61602055 0.20 ENST00000381103.2
KIF2A
kinesin heavy chain member 2A
chr14_+_64971438 0.20 ENST00000555321.1
ZBTB1
zinc finger and BTB domain containing 1
chr1_+_35734616 0.20 ENST00000441447.1
ZMYM4
zinc finger, MYM-type 4
chr3_-_42845922 0.20 ENST00000452906.2
HIGD1A
HIG1 hypoxia inducible domain family, member 1A
chr11_-_64612041 0.20 ENST00000342711.5
CDC42BPG
CDC42 binding protein kinase gamma (DMPK-like)
chr12_-_104531785 0.20 ENST00000551727.1
NFYB
nuclear transcription factor Y, beta
chr7_-_33102399 0.20 ENST00000242210.7
NT5C3A
5'-nucleotidase, cytosolic IIIA
chr5_+_138609441 0.20 ENST00000509990.1
ENST00000506147.1
ENST00000512107.1
MATR3
matrin 3
chr9_-_111775772 0.20 ENST00000325580.6
ENST00000374593.4
ENST00000374595.4
ENST00000325551.4
CTNNAL1
catenin (cadherin-associated protein), alpha-like 1
chr5_+_137801160 0.20 ENST00000239938.4
EGR1
early growth response 1
chr7_-_33102338 0.19 ENST00000610140.1
NT5C3A
5'-nucleotidase, cytosolic IIIA
chrX_+_23925918 0.19 ENST00000379211.3
CXorf58
chromosome X open reading frame 58
chr20_+_55204351 0.19 ENST00000201031.2
TFAP2C
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)

Network of associatons between targets according to the STRING database.

First level regulatory network of EGR1_EGR4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0071264 regulation of eIF2 alpha phosphorylation by amino acid starvation(GO:0060733) regulation of translational initiation in response to starvation(GO:0071262) positive regulation of translational initiation in response to starvation(GO:0071264)
0.3 0.8 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.2 0.9 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.2 0.6 GO:0034148 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of CD40 signaling pathway(GO:2000349)
0.2 0.6 GO:0045212 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.2 0.8 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.2 0.3 GO:2000705 dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.1 0.1 GO:0019860 uracil metabolic process(GO:0019860)
0.1 0.4 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.1 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.1 0.3 GO:0001543 ovarian follicle rupture(GO:0001543)
0.1 0.4 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) T-helper 1 cell activation(GO:0035711) negative regulation of apoptotic cell clearance(GO:2000426)
0.1 0.3 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.1 1.0 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.9 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.1 0.3 GO:1903410 lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine import into cell(GO:1903410)
0.1 0.4 GO:2000176 regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.1 1.2 GO:0033210 leptin-mediated signaling pathway(GO:0033210)
0.1 0.3 GO:0030279 negative regulation of ossification(GO:0030279)
0.1 0.7 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.1 0.4 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.1 0.2 GO:0006679 glucosylceramide biosynthetic process(GO:0006679)
0.1 0.2 GO:0090274 regulation of somatostatin secretion(GO:0090273) positive regulation of somatostatin secretion(GO:0090274)
0.1 0.2 GO:0000961 negative regulation of mitochondrial RNA catabolic process(GO:0000961)
0.1 0.2 GO:0072361 regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361)
0.1 0.5 GO:0006041 glucosamine metabolic process(GO:0006041)
0.1 0.4 GO:0046086 adenosine biosynthetic process(GO:0046086)
0.1 0.3 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.2 GO:0061183 dermatome development(GO:0061054) regulation of dermatome development(GO:0061183) positive regulation of dermatome development(GO:0061184)
0.1 0.2 GO:2000656 regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657)
0.1 0.3 GO:0043335 protein unfolding(GO:0043335)
0.1 0.3 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.1 0.2 GO:0042222 interleukin-1 biosynthetic process(GO:0042222) regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.1 0.5 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1 0.4 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.1 0.3 GO:0008611 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.1 0.4 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.1 0.1 GO:0060300 regulation of cytokine activity(GO:0060300)
0.1 0.3 GO:2000672 cellular response to sorbitol(GO:0072709) negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 0.2 GO:1904833 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874) positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925) positive regulation of superoxide dismutase activity(GO:1901671) positive regulation of removal of superoxide radicals(GO:1904833)
0.1 0.3 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 0.3 GO:0030421 defecation(GO:0030421)
0.1 0.2 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1 0.6 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.6 GO:0060019 radial glial cell differentiation(GO:0060019)
0.0 0.1 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0 0.1 GO:0042137 sequestering of neurotransmitter(GO:0042137)
0.0 0.2 GO:0060694 regulation of cholesterol transporter activity(GO:0060694) negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.0 0.3 GO:0015692 lead ion transport(GO:0015692)
0.0 0.1 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.0 0.0 GO:0044331 cell-cell adhesion mediated by cadherin(GO:0044331) regulation of cell-cell adhesion mediated by cadherin(GO:2000047) positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0 0.2 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.0 0.2 GO:0030862 regulation of polarized epithelial cell differentiation(GO:0030860) positive regulation of polarized epithelial cell differentiation(GO:0030862)
0.0 0.1 GO:0060827 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827) negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.0 0.0 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423) siRNA loading onto RISC involved in RNA interference(GO:0035087)
0.0 0.2 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.0 0.2 GO:0021769 orbitofrontal cortex development(GO:0021769)
0.0 0.1 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.0 0.2 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.0 GO:0051231 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231)
0.0 0.2 GO:0034184 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.0 0.7 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.0 0.2 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.0 0.5 GO:1902961 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.0 0.1 GO:0009726 detection of endogenous stimulus(GO:0009726)
0.0 0.5 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.2 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.2 GO:0048806 genitalia development(GO:0048806)
0.0 0.2 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0 0.1 GO:0033386 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.0 0.5 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.1 GO:2000588 positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588)
0.0 0.1 GO:0051685 maintenance of ER location(GO:0051685)
0.0 0.4 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.4 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.9 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.3 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.1 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.0 0.5 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.1 GO:0043400 cortisol secretion(GO:0043400) regulation of cortisol secretion(GO:0051462)
0.0 0.1 GO:0008057 eye pigment granule organization(GO:0008057)
0.0 0.2 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.1 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.0 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.1 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518) chemorepulsion of axon(GO:0061643)
0.0 0.3 GO:0007135 meiosis II(GO:0007135)
0.0 0.2 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.0 0.2 GO:0034436 glycoprotein transport(GO:0034436)
0.0 0.2 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.2 GO:1903613 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.0 0.2 GO:0060398 regulation of growth hormone receptor signaling pathway(GO:0060398)
0.0 0.1 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.0 0.4 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.3 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.2 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.2 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.8 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 0.2 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.0 0.1 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.1 GO:0033488 cholesterol biosynthetic process via 24,25-dihydrolanosterol(GO:0033488)
0.0 0.5 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.1 GO:0061101 neuroendocrine cell differentiation(GO:0061101)
0.0 0.2 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.0 0.0 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
0.0 0.1 GO:2000685 mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685)
0.0 0.2 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.5 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.1 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.0 0.1 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.0 0.3 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 1.1 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.7 GO:0016180 snRNA processing(GO:0016180)
0.0 0.1 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.1 GO:0090003 regulation of establishment of protein localization to plasma membrane(GO:0090003)
0.0 0.2 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.0 0.3 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.0 0.3 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 0.1 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.2 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.0 0.2 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.2 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.3 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.0 0.5 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.1 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
0.0 0.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.2 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.0 0.1 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.4 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.1 GO:0035865 cellular response to potassium ion(GO:0035865)
0.0 0.1 GO:0051389 inactivation of MAPKK activity(GO:0051389)
0.0 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.2 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0 0.2 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:0061091 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.0 0.1 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.2 GO:0097113 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.0 0.1 GO:0015770 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0 0.1 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.0 0.0 GO:1900168 glial cell-derived neurotrophic factor secretion(GO:0044467) regulation of glial cell-derived neurotrophic factor secretion(GO:1900166) positive regulation of glial cell-derived neurotrophic factor secretion(GO:1900168)
0.0 0.1 GO:0046292 spermatid nucleus elongation(GO:0007290) formaldehyde metabolic process(GO:0046292)
0.0 0.8 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.2 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.0 0.2 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.1 GO:1990180 mitochondrial tRNA 3'-end processing(GO:1990180)
0.0 0.3 GO:0036484 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.0 0.3 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.1 GO:0030575 nuclear body organization(GO:0030575)
0.0 0.1 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.4 GO:0035745 T-helper 2 cell cytokine production(GO:0035745)
0.0 0.2 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500) protein localization to ciliary membrane(GO:1903441)
0.0 0.1 GO:0021793 chemorepulsion of branchiomotor axon(GO:0021793)
0.0 0.2 GO:0033182 regulation of histone ubiquitination(GO:0033182)
0.0 0.1 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 0.1 GO:1904764 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.0 0.1 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.1 GO:0010520 meiotic gene conversion(GO:0006311) regulation of reciprocal meiotic recombination(GO:0010520)
0.0 0.1 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
0.0 0.1 GO:0002011 morphogenesis of an epithelial sheet(GO:0002011)
0.0 0.1 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.0 0.2 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.5 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.1 GO:0035617 stress granule disassembly(GO:0035617)
0.0 0.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 1.7 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.3 GO:1904293 negative regulation of ERAD pathway(GO:1904293)
0.0 0.1 GO:1902525 regulation of protein monoubiquitination(GO:1902525)
0.0 0.2 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.8 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.0 0.3 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0 0.1 GO:0042636 negative regulation of hair cycle(GO:0042636)
0.0 0.1 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.6 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.3 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.0 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.0 0.8 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.1 GO:0070269 pyroptosis(GO:0070269)
0.0 0.0 GO:0070898 RNA polymerase III transcriptional preinitiation complex assembly(GO:0070898)
0.0 0.1 GO:0032252 secretory granule localization(GO:0032252)
0.0 0.3 GO:1904896 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 0.1 GO:0009912 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.0 0.1 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843)
0.0 0.2 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.1 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.1 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.0 0.2 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.0 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.0 0.4 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 0.1 GO:0090669 telomerase RNA stabilization(GO:0090669)
0.0 0.0 GO:0007388 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.0 0.0 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.1 GO:0009137 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 1.1 GO:0006378 mRNA polyadenylation(GO:0006378)
0.0 0.0 GO:0035281 pre-miRNA export from nucleus(GO:0035281)
0.0 0.1 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.1 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.0 0.1 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.0 0.2 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.2 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.2 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.2 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.1 GO:0072276 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.1 GO:1903748 negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
0.0 0.1 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.0 0.0 GO:0071205 protein localization to juxtaparanode region of axon(GO:0071205)
0.0 0.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.3 GO:0010996 response to auditory stimulus(GO:0010996)
0.0 0.1 GO:0060179 male mating behavior(GO:0060179)
0.0 0.1 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.1 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.0 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.0 0.0 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.0 0.8 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.0 0.0 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0 0.2 GO:2000484 positive regulation of interleukin-8 secretion(GO:2000484)
0.0 0.0 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.0 0.1 GO:0060978 angiogenesis involved in coronary vascular morphogenesis(GO:0060978) occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.0 0.1 GO:0043555 regulation of translation in response to stress(GO:0043555)
0.0 0.2 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:0070458 cellular detoxification of nitrogen compound(GO:0070458)
0.0 0.1 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0 0.5 GO:0043114 regulation of vascular permeability(GO:0043114)
0.0 0.1 GO:0034128 negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.0 0.1 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.1 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 0.2 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.1 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.0 GO:0045210 FasL biosynthetic process(GO:0045210)
0.0 0.1 GO:0051893 regulation of focal adhesion assembly(GO:0051893) regulation of cell-substrate junction assembly(GO:0090109)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 GO:0072487 MSL complex(GO:0072487)
0.1 0.7 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 0.2 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.1 0.6 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 0.2 GO:0031213 RSF complex(GO:0031213)
0.1 0.3 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.1 0.5 GO:0016589 NURF complex(GO:0016589)
0.1 0.3 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.3 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.8 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.7 GO:0032039 integrator complex(GO:0032039)
0.0 0.3 GO:0045298 tubulin complex(GO:0045298)
0.0 0.7 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.4 GO:0051286 cell tip(GO:0051286)
0.0 0.5 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.4 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.3 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.2 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.3 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.6 GO:0097227 sperm annulus(GO:0097227)
0.0 0.5 GO:0097433 dense body(GO:0097433)
0.0 0.1 GO:0032302 MutSbeta complex(GO:0032302)
0.0 0.2 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.3 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.2 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.3 GO:0034464 BBSome(GO:0034464)
0.0 0.1 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.0 0.2 GO:0001740 Barr body(GO:0001740)
0.0 0.3 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.3 GO:0070652 HAUS complex(GO:0070652)
0.0 0.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.4 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.2 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.2 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.4 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.2 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.3 GO:0000243 commitment complex(GO:0000243)
0.0 0.2 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.6 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.1 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.5 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.1 GO:0070552 BRISC complex(GO:0070552)
0.0 0.4 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.2 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.2 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 0.1 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0 0.1 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.4 GO:0019908 nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0 0.7 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.3 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 0.1 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.0 GO:0005602 complement component C1 complex(GO:0005602)
0.0 0.1 GO:0097486 multivesicular body lumen(GO:0097486)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.9 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.0 GO:0042565 RNA nuclear export complex(GO:0042565)
0.0 0.1 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.3 GO:0042995 cell projection(GO:0042995)
0.0 0.5 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.1 GO:0071953 elastic fiber(GO:0071953)
0.0 0.2 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.4 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.3 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.3 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.2 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.4 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.0 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 0.0 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.0 0.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.2 GO:0010369 chromocenter(GO:0010369)
0.0 0.1 GO:0090661 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.2 0.7 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.2 0.9 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.1 0.6 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.1 0.4 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.1 0.4 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.1 0.3 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.1 0.3 GO:0016768 spermine synthase activity(GO:0016768)
0.1 1.4 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 0.5 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 0.4 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.1 1.1 GO:0097100 supercoiled DNA binding(GO:0097100)
0.1 0.3 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.1 0.4 GO:0034584 piRNA binding(GO:0034584)
0.1 0.4 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.1 0.2 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.1 0.3 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.2 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.1 0.3 GO:0005287 high-affinity basic amino acid transmembrane transporter activity(GO:0005287) high-affinity arginine transmembrane transporter activity(GO:0005289) high-affinity lysine transmembrane transporter activity(GO:0005292)
0.1 0.2 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.1 0.7 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.5 GO:0035500 MH2 domain binding(GO:0035500)
0.1 0.3 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.1 0.2 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.3 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.0 0.1 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.0 0.3 GO:0015639 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.0 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.3 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 1.8 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.1 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)
0.0 0.1 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
0.0 0.5 GO:0031386 protein tag(GO:0031386)
0.0 0.9 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.5 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.3 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.0 0.1 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.0 0.1 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.5 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 1.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.7 GO:0051400 BH domain binding(GO:0051400)
0.0 0.8 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0016005 phospholipase A2 activator activity(GO:0016005)
0.0 0.1 GO:0008398 sterol 14-demethylase activity(GO:0008398)
0.0 0.4 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0000406 double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.0 0.2 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.3 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.2 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.0 0.1 GO:0001132 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
0.0 0.2 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.2 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.1 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.0 0.1 GO:0016015 morphogen activity(GO:0016015)
0.0 0.1 GO:0004651 polynucleotide 5'-phosphatase activity(GO:0004651)
0.0 0.3 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.1 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.2 GO:0051022 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.4 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.1 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.0 0.2 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.1 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 0.1 GO:0099609 microtubule lateral binding(GO:0099609)
0.0 1.6 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.1 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.0 0.1 GO:0015154 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.3 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.1 GO:0004905 type I interferon receptor activity(GO:0004905)
0.0 0.2 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.6 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.2 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.2 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.1 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.9 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.4 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.6 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0090541 MIT domain binding(GO:0090541)
0.0 0.2 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.7 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.1 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.0 0.0 GO:0047291 neolactotetraosylceramide alpha-2,3-sialyltransferase activity(GO:0004513) lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0005018 platelet-derived growth factor alpha-receptor activity(GO:0005018)
0.0 0.4 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.4 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.6 GO:0004532 exoribonuclease activity(GO:0004532)
0.0 0.5 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.0 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.0 0.0 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0 0.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 1.3 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.4 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.2 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.1 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 0.2 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.3 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.0 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.0 0.1 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.6 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.4 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.1 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.1 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 0.1 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.0 0.2 GO:0036122 BMP binding(GO:0036122)
0.0 0.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.1 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.1 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.0 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.3 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.3 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.1 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.0 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.0 0.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.1 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.4 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 1.5 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 1.5 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.2 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.8 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.6 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.6 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.1 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.9 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.7 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 0.9 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.8 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.0 0.4 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.5 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.5 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 1.1 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.6 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.5 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 1.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.8 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.5 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.2 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.8 REACTOME KINESINS Genes involved in Kinesins
0.0 0.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.4 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.4 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.1 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.6 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.4 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.3 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.4 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.2 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.2 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants