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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for CREB5_CREM_JUNB

Z-value: 1.12

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Transcription factors associated with CREB5_CREM_JUNB

Gene Symbol Gene ID Gene Info
CREB5
ENSG00000146592.12 cAMP responsive element binding protein 5
CREM
ENSG00000095794.15 cAMP responsive element modulator
JUNB
ENSG00000171223.4 JunB proto-oncogene, AP-1 transcription factor subunit

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CREMhg19_v2_chr10_+_35464513_354646310.805.7e-02Click!
CREB5hg19_v2_chr7_+_28725585_28725608-0.562.5e-01Click!
JUNBhg19_v2_chr19_+_12902289_12902310-0.295.7e-01Click!

Activity profile of CREB5_CREM_JUNB motif

Sorted Z-values of CREB5_CREM_JUNB motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_100660833 0.98 ENST00000551642.1
ENST00000416321.1
ENST00000550587.1
ENST00000549249.1
DEPDC4
DEP domain containing 4
chr6_+_30749649 0.86 ENST00000422944.1
HCG20
HLA complex group 20 (non-protein coding)
chr4_+_75311019 0.85 ENST00000502307.1
AREG
amphiregulin
chr1_+_168148273 0.73 ENST00000367830.3
TIPRL
TIP41, TOR signaling pathway regulator-like (S. cerevisiae)
chr20_+_5892147 0.72 ENST00000455042.1
CHGB
chromogranin B (secretogranin 1)
chr4_+_75310851 0.72 ENST00000395748.3
ENST00000264487.2
AREG
amphiregulin
chr20_+_33146510 0.68 ENST00000397709.1
MAP1LC3A
microtubule-associated protein 1 light chain 3 alpha
chr16_+_68057179 0.68 ENST00000567100.1
ENST00000432752.1
ENST00000569289.1
ENST00000564781.1
DUS2
dihydrouridine synthase 2
chr4_+_75480629 0.68 ENST00000380846.3
AREGB
amphiregulin B
chr8_+_40010989 0.66 ENST00000315792.3
C8orf4
chromosome 8 open reading frame 4
chr7_-_140624499 0.66 ENST00000288602.6
BRAF
v-raf murine sarcoma viral oncogene homolog B
chr3_+_38206975 0.63 ENST00000446845.1
ENST00000311806.3
OXSR1
oxidative stress responsive 1
chr4_-_146019335 0.63 ENST00000451299.2
ENST00000507656.1
ENST00000309439.5
ANAPC10
anaphase promoting complex subunit 10
chr6_-_26285737 0.63 ENST00000377727.1
ENST00000289352.1
HIST1H4H
histone cluster 1, H4h
chr16_-_4588391 0.62 ENST00000586728.1
CDIP1
cell death-inducing p53 target 1
chr4_-_156297919 0.61 ENST00000450097.1
MAP9
microtubule-associated protein 9
chr16_+_68056844 0.56 ENST00000565263.1
DUS2
dihydrouridine synthase 2
chr6_-_27440460 0.56 ENST00000377419.1
ZNF184
zinc finger protein 184
chr19_+_2841433 0.55 ENST00000334241.4
ENST00000585966.1
ENST00000591539.1
ZNF555
zinc finger protein 555
chr6_-_27440837 0.55 ENST00000211936.6
ZNF184
zinc finger protein 184
chr4_-_146019693 0.54 ENST00000514390.1
ANAPC10
anaphase promoting complex subunit 10
chr19_-_49622348 0.54 ENST00000408991.2
C19orf73
chromosome 19 open reading frame 73
chr15_+_34394257 0.53 ENST00000397766.2
PGBD4
piggyBac transposable element derived 4
chr5_+_112849373 0.51 ENST00000161863.4
ENST00000515883.1
YTHDC2
YTH domain containing 2
chr3_+_170075436 0.50 ENST00000476188.1
ENST00000259119.4
ENST00000426052.2
SKIL
SKI-like oncogene
chr19_+_55795493 0.48 ENST00000309383.1
BRSK1
BR serine/threonine kinase 1
chr8_+_26149274 0.48 ENST00000522535.1
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr6_-_106773291 0.47 ENST00000343245.3
ATG5
autophagy related 5
chr10_+_35484053 0.46 ENST00000487763.1
ENST00000473940.1
ENST00000488328.1
ENST00000356917.5
CREM
cAMP responsive element modulator
chr4_+_170581213 0.45 ENST00000507875.1
CLCN3
chloride channel, voltage-sensitive 3
chr20_+_10199468 0.45 ENST00000254976.2
ENST00000304886.2
SNAP25
synaptosomal-associated protein, 25kDa
chr19_+_18723660 0.44 ENST00000262817.3
TMEM59L
transmembrane protein 59-like
chr20_+_10199566 0.43 ENST00000430336.1
SNAP25
synaptosomal-associated protein, 25kDa
chr4_-_79860506 0.43 ENST00000295462.3
ENST00000380645.4
ENST00000512733.1
PAQR3
progestin and adipoQ receptor family member III
chr12_+_107168418 0.43 ENST00000392839.2
ENST00000548914.1
ENST00000355478.2
ENST00000552619.1
ENST00000549643.1
RIC8B
RIC8 guanine nucleotide exchange factor B
chr9_-_73029540 0.42 ENST00000377126.2
KLF9
Kruppel-like factor 9
chr12_+_19389814 0.42 ENST00000536974.1
PLEKHA5
pleckstrin homology domain containing, family A member 5
chr8_-_94928861 0.42 ENST00000607097.1
MIR378D2
microRNA 378d-2
chr5_-_78809950 0.42 ENST00000334082.6
HOMER1
homer homolog 1 (Drosophila)
chr7_-_45128472 0.41 ENST00000490531.2
NACAD
NAC alpha domain containing
chr17_+_41177220 0.41 ENST00000587250.2
ENST00000544533.1
RND2
Rho family GTPase 2
chr6_-_37225367 0.41 ENST00000336655.2
TMEM217
transmembrane protein 217
chr6_-_106773491 0.41 ENST00000360666.4
ATG5
autophagy related 5
chr12_+_54378923 0.41 ENST00000303460.4
HOXC10
homeobox C10
chrX_-_135056106 0.40 ENST00000433339.2
MMGT1
membrane magnesium transporter 1
chr11_-_18343725 0.40 ENST00000531848.1
HPS5
Hermansky-Pudlak syndrome 5
chr12_-_4754339 0.40 ENST00000228850.1
AKAP3
A kinase (PRKA) anchor protein 3
chr8_-_17104099 0.39 ENST00000524358.1
CNOT7
CCR4-NOT transcription complex, subunit 7
chr22_+_37959647 0.39 ENST00000415670.1
CDC42EP1
CDC42 effector protein (Rho GTPase binding) 1
chr2_+_37571845 0.39 ENST00000537448.1
QPCT
glutaminyl-peptide cyclotransferase
chr4_+_146019421 0.39 ENST00000502586.1
ABCE1
ATP-binding cassette, sub-family E (OABP), member 1
chr2_-_224467002 0.39 ENST00000421386.1
ENST00000433889.1
SCG2
secretogranin II
chr20_-_44420507 0.39 ENST00000243938.4
WFDC3
WAP four-disulfide core domain 3
chr7_+_138915102 0.39 ENST00000486663.1
UBN2
ubinuclein 2
chr6_-_30523865 0.39 ENST00000433809.1
GNL1
guanine nucleotide binding protein-like 1
chr1_-_22109682 0.38 ENST00000400301.1
ENST00000532737.1
USP48
ubiquitin specific peptidase 48
chr5_-_95297534 0.38 ENST00000513343.1
ENST00000431061.2
ELL2
elongation factor, RNA polymerase II, 2
chr3_+_184056614 0.38 ENST00000453072.1
FAM131A
family with sequence similarity 131, member A
chr8_-_67090825 0.38 ENST00000276571.3
CRH
corticotropin releasing hormone
chr12_-_31881944 0.37 ENST00000537562.1
ENST00000537960.1
ENST00000536761.1
ENST00000542781.1
ENST00000457428.2
AMN1
antagonist of mitotic exit network 1 homolog (S. cerevisiae)
chr6_-_37225391 0.37 ENST00000356757.2
TMEM217
transmembrane protein 217
chrX_+_152224766 0.37 ENST00000370265.4
ENST00000447306.1
PNMA3
paraneoplastic Ma antigen 3
chr11_+_4116054 0.37 ENST00000423050.2
RRM1
ribonucleotide reductase M1
chr1_+_66797687 0.37 ENST00000371045.5
ENST00000531025.1
ENST00000526197.1
PDE4B
phosphodiesterase 4B, cAMP-specific
chr1_-_70820357 0.37 ENST00000370944.4
ENST00000262346.6
ANKRD13C
ankyrin repeat domain 13C
chr18_+_77867177 0.37 ENST00000560752.1
ADNP2
ADNP homeobox 2
chr8_-_27115903 0.36 ENST00000350889.4
ENST00000519997.1
ENST00000519614.1
ENST00000522908.1
ENST00000265770.7
STMN4
stathmin-like 4
chr18_+_23806437 0.36 ENST00000578121.1
TAF4B
TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
chr20_-_14318248 0.36 ENST00000378053.3
ENST00000341420.4
FLRT3
fibronectin leucine rich transmembrane protein 3
chr12_+_100661156 0.35 ENST00000360820.2
SCYL2
SCY1-like 2 (S. cerevisiae)
chr6_-_70506963 0.35 ENST00000370577.3
LMBRD1
LMBR1 domain containing 1
chr8_+_26240666 0.35 ENST00000523949.1
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr19_-_10024496 0.35 ENST00000593091.1
OLFM2
olfactomedin 2
chr2_-_190627481 0.35 ENST00000264151.5
ENST00000520350.1
ENST00000521630.1
ENST00000517895.1
OSGEPL1
O-sialoglycoprotein endopeptidase-like 1
chr20_+_55108302 0.35 ENST00000371325.1
FAM209B
family with sequence similarity 209, member B
chr19_-_9649303 0.34 ENST00000253115.2
ZNF426
zinc finger protein 426
chr22_+_31518938 0.34 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
INPP5J
inositol polyphosphate-5-phosphatase J
chr14_+_68086515 0.34 ENST00000261783.3
ARG2
arginase 2
chr8_+_26149007 0.34 ENST00000380737.3
ENST00000524169.1
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr1_+_70820451 0.34 ENST00000361764.4
ENST00000359875.5
ENST00000370940.5
ENST00000531950.1
ENST00000432224.1
HHLA3
HERV-H LTR-associating 3
chrX_-_83757399 0.34 ENST00000373177.2
ENST00000297977.5
ENST00000506585.2
ENST00000449553.2
HDX
highly divergent homeobox
chr16_+_68057153 0.33 ENST00000358896.6
ENST00000568099.2
DUS2
dihydrouridine synthase 2
chr11_+_18416133 0.33 ENST00000227157.4
ENST00000478970.2
ENST00000495052.1
LDHA
lactate dehydrogenase A
chr4_+_170541678 0.33 ENST00000360642.3
ENST00000512813.1
CLCN3
chloride channel, voltage-sensitive 3
chr2_-_216300784 0.33 ENST00000421182.1
ENST00000432072.2
ENST00000323926.6
ENST00000336916.4
ENST00000357867.4
ENST00000359671.1
ENST00000346544.3
ENST00000345488.5
ENST00000357009.2
ENST00000446046.1
ENST00000356005.4
ENST00000443816.1
ENST00000426059.1
ENST00000354785.4
FN1
fibronectin 1
chr1_-_154600421 0.33 ENST00000368471.3
ENST00000292205.5
ADAR
adenosine deaminase, RNA-specific
chr3_-_119182523 0.33 ENST00000319172.5
TMEM39A
transmembrane protein 39A
chr16_+_56225248 0.33 ENST00000262493.6
GNAO1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr3_-_69249863 0.33 ENST00000478263.1
ENST00000462512.1
FRMD4B
FERM domain containing 4B
chr6_-_106773610 0.33 ENST00000369076.3
ENST00000369070.1
ATG5
autophagy related 5
chr6_+_44355257 0.32 ENST00000371477.3
CDC5L
cell division cycle 5-like
chr17_-_7165662 0.32 ENST00000571881.2
ENST00000360325.7
CLDN7
claudin 7
chr6_+_56819773 0.32 ENST00000370750.2
BEND6
BEN domain containing 6
chr4_-_146019287 0.31 ENST00000502847.1
ENST00000513054.1
ANAPC10
anaphase promoting complex subunit 10
chr4_+_170541835 0.31 ENST00000504131.2
CLCN3
chloride channel, voltage-sensitive 3
chr3_-_154042235 0.31 ENST00000308361.6
ENST00000496811.1
ENST00000544526.1
DHX36
DEAH (Asp-Glu-Ala-His) box polypeptide 36
chr1_+_39456895 0.31 ENST00000432648.3
ENST00000446189.2
ENST00000372984.4
AKIRIN1
akirin 1
chr14_+_88852059 0.30 ENST00000045347.7
SPATA7
spermatogenesis associated 7
chr5_-_133706695 0.30 ENST00000521755.1
ENST00000523054.1
ENST00000435240.2
ENST00000609654.1
ENST00000536186.1
ENST00000609383.1
CDKL3
cyclin-dependent kinase-like 3
chr12_+_69004736 0.30 ENST00000545720.2
RAP1B
RAP1B, member of RAS oncogene family
chr14_+_102276209 0.30 ENST00000445439.3
ENST00000334743.5
ENST00000557095.1
PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr12_+_112856690 0.30 ENST00000392597.1
ENST00000351677.2
PTPN11
protein tyrosine phosphatase, non-receptor type 11
chr4_+_57253672 0.29 ENST00000602927.1
RP11-646I6.5
RP11-646I6.5
chrX_-_47863348 0.29 ENST00000376943.3
ENST00000396965.1
ENST00000305127.6
ZNF182
zinc finger protein 182
chr19_-_39402798 0.29 ENST00000571838.1
CTC-360G5.1
coiled-coil glutamate-rich protein 2
chr11_+_118230287 0.29 ENST00000252108.3
ENST00000431736.2
UBE4A
ubiquitination factor E4A
chr6_+_30908747 0.29 ENST00000462446.1
ENST00000304311.2
DPCR1
diffuse panbronchiolitis critical region 1
chr3_+_10068095 0.29 ENST00000287647.3
ENST00000383807.1
ENST00000383806.1
ENST00000419585.1
FANCD2
Fanconi anemia, complementation group D2
chr14_-_24017647 0.29 ENST00000555334.1
ZFHX2
zinc finger homeobox 2
chr8_-_18711866 0.29 ENST00000519851.1
PSD3
pleckstrin and Sec7 domain containing 3
chr8_-_101964231 0.28 ENST00000521309.1
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr20_-_5591626 0.28 ENST00000379019.4
GPCPD1
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr11_+_4116005 0.28 ENST00000300738.5
RRM1
ribonucleotide reductase M1
chr10_+_124134201 0.28 ENST00000368990.3
ENST00000368988.1
ENST00000368989.2
ENST00000463663.2
PLEKHA1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr11_+_66059339 0.28 ENST00000327259.4
TMEM151A
transmembrane protein 151A
chr3_+_113251143 0.28 ENST00000264852.4
ENST00000393830.3
SIDT1
SID1 transmembrane family, member 1
chr11_+_76813886 0.28 ENST00000529803.1
OMP
olfactory marker protein
chr11_+_18416103 0.28 ENST00000543445.1
ENST00000430553.2
ENST00000396222.2
ENST00000535451.1
LDHA
lactate dehydrogenase A
chr3_-_52312337 0.27 ENST00000469000.1
WDR82
WD repeat domain 82
chr12_+_69004805 0.27 ENST00000541216.1
RAP1B
RAP1B, member of RAS oncogene family
chr2_+_114195268 0.27 ENST00000259199.4
ENST00000416503.2
ENST00000433343.2
CBWD2
COBW domain containing 2
chr5_+_138210919 0.27 ENST00000522013.1
ENST00000520260.1
ENST00000523298.1
ENST00000520865.1
ENST00000519634.1
ENST00000517533.1
ENST00000523685.1
ENST00000519768.1
ENST00000517656.1
ENST00000521683.1
ENST00000521640.1
ENST00000519116.1
CTNNA1
catenin (cadherin-associated protein), alpha 1, 102kDa
chrX_+_10126488 0.27 ENST00000380829.1
ENST00000421085.2
ENST00000454850.1
CLCN4
chloride channel, voltage-sensitive 4
chr4_-_39367949 0.26 ENST00000503784.1
ENST00000349703.2
ENST00000381897.1
RFC1
replication factor C (activator 1) 1, 145kDa
chr3_-_154042205 0.26 ENST00000329463.5
DHX36
DEAH (Asp-Glu-Ala-His) box polypeptide 36
chr3_-_195938256 0.26 ENST00000296326.3
ZDHHC19
zinc finger, DHHC-type containing 19
chr5_+_56469843 0.26 ENST00000514387.2
GPBP1
GC-rich promoter binding protein 1
chr7_-_139756791 0.26 ENST00000489809.1
PARP12
poly (ADP-ribose) polymerase family, member 12
chr4_-_76598544 0.26 ENST00000515457.1
ENST00000357854.3
G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr17_+_56769924 0.26 ENST00000461271.1
ENST00000583539.1
ENST00000337432.4
ENST00000421782.2
RAD51C
RAD51 paralog C
chrX_+_155110956 0.26 ENST00000286448.6
ENST00000262640.6
ENST00000460621.1
VAMP7
vesicle-associated membrane protein 7
chr10_-_90967063 0.25 ENST00000371852.2
CH25H
cholesterol 25-hydroxylase
chr15_+_89905705 0.25 ENST00000560008.1
ENST00000561327.1
LINC00925
long intergenic non-protein coding RNA 925
chr10_+_119000604 0.25 ENST00000298472.5
SLC18A2
solute carrier family 18 (vesicular monoamine transporter), member 2
chr2_+_37571717 0.25 ENST00000338415.3
ENST00000404976.1
QPCT
glutaminyl-peptide cyclotransferase
chr8_-_66754172 0.25 ENST00000401827.3
PDE7A
phosphodiesterase 7A
chr14_+_38065052 0.25 ENST00000556845.1
TTC6
tetratricopeptide repeat domain 6
chr2_-_43823119 0.25 ENST00000403856.1
ENST00000404790.1
ENST00000405975.2
ENST00000415080.2
THADA
thyroid adenoma associated
chr5_+_75904918 0.25 ENST00000514001.1
ENST00000396234.3
ENST00000509074.1
IQGAP2
IQ motif containing GTPase activating protein 2
chr3_-_33686925 0.25 ENST00000485378.2
ENST00000313350.6
ENST00000487200.1
CLASP2
cytoplasmic linker associated protein 2
chr4_-_140477910 0.25 ENST00000404104.3
SETD7
SET domain containing (lysine methyltransferase) 7
chr6_+_47445467 0.25 ENST00000359314.5
CD2AP
CD2-associated protein
chr5_-_57756087 0.25 ENST00000274289.3
PLK2
polo-like kinase 2
chr2_-_43823093 0.25 ENST00000405006.4
THADA
thyroid adenoma associated
chr6_-_19804973 0.25 ENST00000457670.1
ENST00000607810.1
ENST00000606628.1
RP4-625H18.2
RP4-625H18.2
chr8_+_42128861 0.24 ENST00000518983.1
IKBKB
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
chr3_-_107941209 0.24 ENST00000492106.1
IFT57
intraflagellar transport 57 homolog (Chlamydomonas)
chr14_+_32030582 0.24 ENST00000550649.1
ENST00000281081.7
NUBPL
nucleotide binding protein-like
chr4_-_76598326 0.24 ENST00000503660.1
G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr12_-_12715266 0.24 ENST00000228862.2
DUSP16
dual specificity phosphatase 16
chr8_+_38243821 0.24 ENST00000519476.2
LETM2
leucine zipper-EF-hand containing transmembrane protein 2
chr11_-_3818688 0.24 ENST00000355260.3
ENST00000397004.4
ENST00000397007.4
ENST00000532475.1
NUP98
nucleoporin 98kDa
chr17_+_29421987 0.24 ENST00000431387.4
NF1
neurofibromin 1
chr14_-_80678512 0.24 ENST00000553968.1
DIO2
deiodinase, iodothyronine, type II
chr14_-_23762777 0.24 ENST00000431326.2
HOMEZ
homeobox and leucine zipper encoding
chr4_-_57253587 0.24 ENST00000513376.1
ENST00000602986.1
ENST00000434343.2
ENST00000451613.1
ENST00000205214.6
ENST00000502617.1
AASDH
aminoadipate-semialdehyde dehydrogenase
chr12_+_108079664 0.23 ENST00000541166.1
PWP1
PWP1 homolog (S. cerevisiae)
chr2_+_232457569 0.23 ENST00000313965.2
C2orf57
chromosome 2 open reading frame 57
chr8_+_134203303 0.23 ENST00000519433.1
ENST00000517423.1
ENST00000377863.2
ENST00000220856.6
WISP1
WNT1 inducible signaling pathway protein 1
chr5_+_56469939 0.23 ENST00000506184.2
GPBP1
GC-rich promoter binding protein 1
chr14_+_35515582 0.23 ENST00000382406.3
FAM177A1
family with sequence similarity 177, member A1
chr4_-_104119488 0.23 ENST00000514974.1
CENPE
centromere protein E, 312kDa
chr20_+_58179582 0.23 ENST00000371015.1
ENST00000395639.4
PHACTR3
phosphatase and actin regulator 3
chr7_+_120591170 0.23 ENST00000431467.1
ING3
inhibitor of growth family, member 3
chr6_-_10694766 0.23 ENST00000460742.2
ENST00000259983.3
ENST00000379586.1
C6orf52
chromosome 6 open reading frame 52
chr1_+_209878182 0.23 ENST00000367027.3
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr10_+_27444268 0.23 ENST00000375940.4
ENST00000342386.6
MASTL
microtubule associated serine/threonine kinase-like
chr9_-_86322831 0.22 ENST00000257468.7
UBQLN1
ubiquilin 1
chr8_+_133787586 0.22 ENST00000395379.1
ENST00000395386.2
ENST00000337920.4
PHF20L1
PHD finger protein 20-like 1
chr4_-_113558014 0.22 ENST00000503172.1
ENST00000505019.1
ENST00000309071.5
C4orf21
chromosome 4 open reading frame 21
chr5_-_95297678 0.22 ENST00000237853.4
ELL2
elongation factor, RNA polymerase II, 2
chr7_+_89975979 0.22 ENST00000257659.8
ENST00000222511.6
ENST00000417207.1
GTPBP10
GTP-binding protein 10 (putative)
chr19_+_44100632 0.22 ENST00000533118.1
ZNF576
zinc finger protein 576
chr2_-_198175495 0.22 ENST00000409153.1
ENST00000409919.1
ENST00000539527.1
ANKRD44
ankyrin repeat domain 44
chr2_-_202645835 0.22 ENST00000264276.6
ALS2
amyotrophic lateral sclerosis 2 (juvenile)
chr11_-_82782952 0.22 ENST00000534141.1
RAB30
RAB30, member RAS oncogene family
chr14_+_23025534 0.22 ENST00000557595.1
AE000662.92
Uncharacterized protein
chr14_+_102276132 0.21 ENST00000350249.3
ENST00000557621.1
ENST00000556946.1
PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr15_+_66797627 0.21 ENST00000565627.1
ENST00000564179.1
ZWILCH
zwilch kinetochore protein
chr1_-_86861660 0.21 ENST00000486215.1
ODF2L
outer dense fiber of sperm tails 2-like
chr22_+_32340481 0.21 ENST00000397492.1
YWHAH
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
chr4_-_156298087 0.21 ENST00000311277.4
MAP9
microtubule-associated protein 9
chr1_+_22379179 0.21 ENST00000315554.8
ENST00000421089.2
CDC42
cell division cycle 42
chr11_+_18343800 0.21 ENST00000453096.2
GTF2H1
general transcription factor IIH, polypeptide 1, 62kDa
chr4_+_128802016 0.21 ENST00000270861.5
ENST00000515069.1
ENST00000513090.1
ENST00000507249.1
PLK4
polo-like kinase 4
chr15_+_42841008 0.21 ENST00000260372.3
ENST00000568876.1
ENST00000568846.2
ENST00000562398.1
HAUS2
HAUS augmin-like complex, subunit 2
chr6_+_135818907 0.21 ENST00000579339.1
ENST00000580741.1
LINC00271
long intergenic non-protein coding RNA 271
chr8_-_101964265 0.21 ENST00000395958.2
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr14_+_96671016 0.21 ENST00000542454.2
ENST00000554311.1
ENST00000306005.3
ENST00000539359.1
ENST00000553811.1
BDKRB2
RP11-404P21.8
bradykinin receptor B2
Uncharacterized protein
chr1_+_166808692 0.21 ENST00000367876.4
POGK
pogo transposable element with KRAB domain
chr19_-_9649253 0.21 ENST00000593003.1
ZNF426
zinc finger protein 426
chr1_-_203274418 0.21 ENST00000457348.1
RP11-134P9.1
long intergenic non-protein coding RNA 1136
chr4_+_145567297 0.21 ENST00000434550.2
HHIP
hedgehog interacting protein
chr18_+_23806382 0.20 ENST00000400466.2
TAF4B
TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
chr17_+_53342311 0.20 ENST00000226067.5
HLF
hepatic leukemia factor
chr11_-_94965667 0.20 ENST00000542176.1
ENST00000278499.2
SESN3
sestrin 3
chr17_+_66508154 0.20 ENST00000358598.2
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha
chr7_-_6388389 0.20 ENST00000578372.1
FAM220A
family with sequence similarity 220, member A
chr4_-_156297949 0.20 ENST00000515654.1
MAP9
microtubule-associated protein 9
chr21_-_40720974 0.20 ENST00000380748.1
HMGN1
high mobility group nucleosome binding domain 1

Network of associatons between targets according to the STRING database.

First level regulatory network of CREB5_CREM_JUNB

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.2 0.6 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.2 0.6 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.2 1.2 GO:0048388 endosomal lumen acidification(GO:0048388)
0.2 1.2 GO:2000619 negative regulation of histone H4-K16 acetylation(GO:2000619)
0.2 0.5 GO:1901895 negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.2 1.6 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.2 1.6 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.1 0.4 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 0.4 GO:1904235 regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237)
0.1 0.4 GO:0071314 cellular response to cocaine(GO:0071314)
0.1 0.3 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.1 0.3 GO:1901340 negative regulation of store-operated calcium channel activity(GO:1901340)
0.1 0.3 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.1 0.7 GO:1900020 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.1 0.7 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 0.4 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.1 0.4 GO:0045208 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.1 0.2 GO:1903722 regulation of centriole elongation(GO:1903722)
0.1 1.1 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.1 0.7 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.1 0.3 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.3 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
0.1 0.3 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) sequestering of neurotransmitter(GO:0042137)
0.1 0.5 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1 0.3 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.1 0.2 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.1 0.3 GO:1990637 response to prolactin(GO:1990637)
0.1 0.4 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.1 0.2 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.1 0.3 GO:0061582 intestinal epithelial cell migration(GO:0061582)
0.1 0.6 GO:1902739 interferon-alpha secretion(GO:0072642) telomerase RNA stabilization(GO:0090669) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.1 0.1 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.1 0.2 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.1 0.7 GO:0010040 response to iron(II) ion(GO:0010040)
0.1 0.2 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.1 0.4 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.1 0.2 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.1 0.2 GO:0070121 pronephric nephron morphogenesis(GO:0039007) pronephric nephron tubule morphogenesis(GO:0039008) pronephric duct development(GO:0039022) pronephric duct morphogenesis(GO:0039023) Kupffer's vesicle development(GO:0070121)
0.1 0.4 GO:0051414 response to cortisol(GO:0051414)
0.1 0.5 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.1 0.2 GO:1990108 protein linear deubiquitination(GO:1990108)
0.1 0.4 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.1 0.5 GO:0060701 negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702)
0.1 0.1 GO:1902232 regulation of positive thymic T cell selection(GO:1902232)
0.1 0.3 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.5 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0006429 glutaminyl-tRNA aminoacylation(GO:0006425) leucyl-tRNA aminoacylation(GO:0006429)
0.0 0.2 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.3 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.1 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.0 0.9 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.1 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.0 0.5 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.0 0.2 GO:0044026 DNA hypermethylation(GO:0044026) hypermethylation of CpG island(GO:0044027)
0.0 0.1 GO:0060164 amygdala development(GO:0021764) regulation of timing of neuron differentiation(GO:0060164)
0.0 0.2 GO:0061083 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.0 0.2 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.0 0.4 GO:0007135 meiosis II(GO:0007135)
0.0 0.2 GO:0010847 regulation of chromatin assembly(GO:0010847) protein auto-ADP-ribosylation(GO:0070213)
0.0 1.1 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.1 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 0.5 GO:0035437 maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0 0.2 GO:0035617 stress granule disassembly(GO:0035617)
0.0 0.6 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.2 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.0 0.4 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.2 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.0 0.5 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.2 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.2 GO:0045829 negative regulation of isotype switching(GO:0045829)
0.0 0.4 GO:0003344 pericardium morphogenesis(GO:0003344)
0.0 0.2 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.5 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.3 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.2 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.0 0.2 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.0 0.1 GO:1904106 protein localization to microvillus(GO:1904106)
0.0 0.4 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.1 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.1 GO:0071684 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.1 GO:0048687 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.0 0.6 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.4 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.6 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.5 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.2 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.1 GO:1990180 mitochondrial tRNA 3'-end processing(GO:1990180)
0.0 0.1 GO:1990502 dense core granule maturation(GO:1990502)
0.0 0.5 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.1 GO:0043605 cellular amide catabolic process(GO:0043605)
0.0 0.2 GO:0030002 cellular anion homeostasis(GO:0030002) cellular monovalent inorganic anion homeostasis(GO:0030320)
0.0 0.1 GO:0002071 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.0 0.0 GO:0055064 chloride ion homeostasis(GO:0055064)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.6 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.4 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.3 GO:0000050 urea cycle(GO:0000050)
0.0 0.2 GO:0048539 bone marrow development(GO:0048539)
0.0 0.6 GO:0006206 pyrimidine nucleobase metabolic process(GO:0006206)
0.0 0.3 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.3 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 0.1 GO:0051664 nuclear pore distribution(GO:0031081) nuclear pore localization(GO:0051664)
0.0 0.3 GO:0001553 luteinization(GO:0001553)
0.0 0.1 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.0 0.2 GO:0045955 negative regulation of calcium ion-dependent exocytosis(GO:0045955)
0.0 0.1 GO:0043335 protein unfolding(GO:0043335)
0.0 0.1 GO:0021569 rhombomere 3 development(GO:0021569)
0.0 0.2 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.0 0.3 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.0 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.1 GO:0032472 Golgi calcium ion transport(GO:0032472)
0.0 0.2 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.2 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.3 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.5 GO:0008211 glucocorticoid metabolic process(GO:0008211)
0.0 0.1 GO:2000182 positive regulation of mitochondrial DNA metabolic process(GO:1901860) regulation of progesterone biosynthetic process(GO:2000182)
0.0 0.1 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 0.2 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.1 GO:0097252 oligodendrocyte apoptotic process(GO:0097252)
0.0 0.8 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.2 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.0 0.3 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.1 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.0 0.1 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.0 0.1 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.4 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.2 GO:0090487 toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487)
0.0 0.0 GO:0021503 neural fold bending(GO:0021503)
0.0 0.1 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.7 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0 0.1 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.0 0.1 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.0 0.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.0 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.1 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.1 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.0 0.2 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.3 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.2 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.1 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.2 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.0 0.0 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.0 0.8 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.1 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.0 0.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.5 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.4 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.0 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.1 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.4 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.2 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.0 0.2 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.2 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.0 0.2 GO:0014066 regulation of phosphatidylinositol 3-kinase signaling(GO:0014066)
0.0 0.0 GO:0070898 RNA polymerase III transcriptional preinitiation complex assembly(GO:0070898)
0.0 0.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.1 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.1 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.1 GO:0031268 pseudopodium organization(GO:0031268)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0075341 host cell PML body(GO:0075341)
0.1 1.2 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.1 0.5 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 0.9 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.1 0.4 GO:0005873 plus-end kinesin complex(GO:0005873)
0.1 0.4 GO:1990423 RZZ complex(GO:1990423)
0.1 0.6 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1 0.8 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 1.1 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
0.1 0.4 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.1 0.4 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.1 0.5 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 0.3 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 0.4 GO:0097452 GAIT complex(GO:0097452)
0.1 0.7 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.1 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.0 0.3 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.3 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.3 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.3 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 1.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.1 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.7 GO:0044754 autolysosome(GO:0044754)
0.0 0.2 GO:0098536 deuterosome(GO:0098536)
0.0 0.4 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.4 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.3 GO:0070083 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.3 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 1.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:0044292 dendrite terminus(GO:0044292)
0.0 0.0 GO:1990742 microvesicle(GO:1990742)
0.0 0.2 GO:0043196 varicosity(GO:0043196)
0.0 0.2 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.4 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.2 GO:0035976 AP1 complex(GO:0035976)
0.0 0.3 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.1 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.1 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.3 GO:0016600 flotillin complex(GO:0016600)
0.0 0.2 GO:0000439 core TFIIH complex(GO:0000439)
0.0 1.3 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.0 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.0 0.5 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.4 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.2 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.1 GO:0000346 transcription export complex(GO:0000346)
0.0 0.2 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.8 GO:0031941 filamentous actin(GO:0031941)
0.0 0.2 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.2 1.2 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.2 1.2 GO:0019776 Atg8 ligase activity(GO:0019776)
0.2 1.6 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 0.4 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.1 0.4 GO:0015235 cobalamin transporter activity(GO:0015235)
0.1 0.3 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.1 0.4 GO:0032427 GBD domain binding(GO:0032427)
0.1 0.3 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 0.6 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 0.2 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.1 0.3 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.1 0.2 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 1.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 0.3 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.2 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.1 0.6 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 0.2 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 0.5 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.1 0.3 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.1 0.2 GO:0031177 phosphopantetheine binding(GO:0031177)
0.0 0.1 GO:0004823 glutamine-tRNA ligase activity(GO:0004819) leucine-tRNA ligase activity(GO:0004823)
0.0 0.1 GO:0051908 double-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0051908)
0.0 0.1 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.0 0.2 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.0 0.3 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 0.4 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.6 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 0.2 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 0.6 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.5 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.2 GO:0016672 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.0 0.8 GO:0048156 tau protein binding(GO:0048156)
0.0 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.2 GO:0050436 microfibril binding(GO:0050436)
0.0 0.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.3 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.2 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.3 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.0 0.2 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.2 GO:0097108 hedgehog family protein binding(GO:0097108)
0.0 0.2 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.7 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.3 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 1.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.5 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.4 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.3 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.0 0.3 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.1 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.7 GO:0005112 Notch binding(GO:0005112)
0.0 0.3 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 1.0 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.1 GO:1904047 histone methyltransferase activity (H3-K9 specific)(GO:0046974) S-adenosyl-L-methionine binding(GO:1904047)
0.0 0.3 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 1.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.7 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.5 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.3 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.1 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.4 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.2 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.4 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.1 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0097677 STAT family protein binding(GO:0097677)
0.0 0.5 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.1 GO:0035473 lipase binding(GO:0035473)
0.0 0.1 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.1 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.0 0.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.0 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.0 0.5 GO:0005521 lamin binding(GO:0005521)
0.0 0.0 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.4 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.4 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.0 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.6 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.8 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.7 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.8 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 1.2 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 1.3 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 1.5 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.6 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 1.2 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.7 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.3 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.5 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.8 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 1.4 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.9 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.3 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 1.1 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.7 REACTOME KINESINS Genes involved in Kinesins
0.0 0.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.8 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.5 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.1 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.0 0.2 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.2 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.6 REACTOME G1 PHASE Genes involved in G1 Phase