ISMARA results: CEBPG

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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for CEBPG

Z-value: 0.90

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Transcription factors associated with CEBPG

Gene Symbol	Gene ID	Gene Info
CEBPG Ensembl NCBI GeneCards UniProt	ENSG00000153879.4	CCAAT enhancer binding protein gamma

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
CEBPG	hg19_v2_chr19_+_33865218_33865254	0.18	7.4e-01	Click!

Activity profile of CEBPG motif

Sorted Z-values of CEBPG motif

Top targets:

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr12_+_72058130 Show fit	1.36	ENST00000547843.1	THAP2 Ensembl NCBI GeneCards UniProt Show fit	THAP domain containing, apoptosis associated protein 2
chr11_+_18287721 Show fit	1.18	ENST00000356524.4	SAA1 Ensembl NCBI GeneCards UniProt Show fit	serum amyloid A1
chr6_+_31895467 Show fit	1.16	ENST00000556679.1 ENST00000456570.1	CFB Ensembl NCBI GeneCards UniProt Show fit CFB Ensembl NCBI GeneCards UniProt Show fit	complement factor B Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr3_-_148939598 Show fit	0.91	ENST00000455472.3	CP Ensembl NCBI GeneCards UniProt Show fit	ceruloplasmin (ferroxidase)
chr6_+_31895480 Show fit	0.90	ENST00000418949.2 ENST00000383177.3 ENST00000477310.1	C2 Ensembl NCBI GeneCards UniProt Show fit CFB Ensembl NCBI GeneCards UniProt Show fit	complement component 2 Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr9_+_130911723 Show fit	0.77	ENST00000277480.2 ENST00000373013.2 ENST00000540948.1	LCN2 Ensembl NCBI GeneCards UniProt Show fit	lipocalin 2
chr11_+_18287801 Show fit	0.75	ENST00000532858.1 ENST00000405158.2	SAA1 Ensembl NCBI GeneCards UniProt Show fit	serum amyloid A1
chr8_-_121824374 Show fit	0.68	ENST00000517992.1	SNTB1 Ensembl NCBI GeneCards UniProt Show fit	syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr1_+_93645314 Show fit	0.67	ENST00000343253.7	CCDC18 Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 18
chr3_-_148939835 Show fit	0.62	ENST00000264613.6	CP Ensembl NCBI GeneCards UniProt Show fit	ceruloplasmin (ferroxidase)

Showing 1 to 10 of 145 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of CEBPG

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.1	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	2.0	GO:0050716	positive regulation of interleukin-1 secretion(GO:0050716)
0.0	1.4	GO:0006825	copper ion transport(GO:0006825)
0.2	1.2	GO:0015688	iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.2	1.1	GO:0001878	response to yeast(GO:0001878)
0.1	0.9	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.2	0.7	GO:1903045	neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.0	0.7	GO:0032731	positive regulation of interleukin-1 beta production(GO:0032731)
0.2	0.6	GO:0046725	negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.1	0.6	GO:0035234	smooth muscle adaptation(GO:0014805) ectopic germ cell programmed cell death(GO:0035234) negative regulation of adiponectin secretion(GO:0070164)

Showing 1 to 10 of 37 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	4.1	GO:0072562	blood microparticle(GO:0072562)
0.1	1.8	GO:0071682	endocytic vesicle lumen(GO:0071682)
0.0	1.4	GO:0035580	specific granule lumen(GO:0035580)
0.0	0.7	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1	0.5	GO:0097452	GAIT complex(GO:0097452)
0.0	0.4	GO:0043203	axon hillock(GO:0043203)
0.0	0.3	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.3	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.0	0.2	GO:0033263	CORVET complex(GO:0033263)
0.0	0.2	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)

Showing 1 to 10 of 10 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.1	GO:0001848	complement binding(GO:0001848)
0.0	2.1	GO:0042056	chemoattractant activity(GO:0042056)
0.2	1.5	GO:0016724	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1	0.9	GO:0102338	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0	0.8	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.7	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	0.6	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.1	0.5	GO:0001849	complement component C1q binding(GO:0001849)
0.0	0.5	GO:1990380	Lys48-specific deubiquitinase activity(GO:1990380)
0.0	0.5	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)

Showing 1 to 10 of 21 entries

Gene overrepresentation in C2:CP category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.1	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	1.9	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	1.5	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.0	1.2	PID IL27 PATHWAY	IL27-mediated signaling events
0.1	0.6	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.0	0.5	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.5	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.

Showing 1 to 7 of 7 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.6	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.1	1.9	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	1.5	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.0	0.9	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	0.7	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.7	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.6	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	0.2	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts

Showing 1 to 8 of 8 entries

Results for CEBPG

Z-value: 0.90

Motif logo

Transcription factors associated with CEBPG

Activity-expression correlation:

Activity profile of CEBPG motif

Sorted Z-values of CEBPG motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of CEBPG

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: