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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for CEBPA

Z-value: 1.97

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Transcription factors associated with CEBPA

Gene Symbol Gene ID Gene Info
CEBPA
ENSG00000245848.2 CCAAT enhancer binding protein alpha

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CEBPAhg19_v2_chr19_-_33793430_33793470-0.453.7e-01Click!

Activity profile of CEBPA motif

Sorted Z-values of CEBPA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_72058130 2.84 ENST00000547843.1
THAP2
THAP domain containing, apoptosis associated protein 2
chr4_-_155533787 2.77 ENST00000407946.1
ENST00000405164.1
ENST00000336098.3
ENST00000393846.2
ENST00000404648.3
ENST00000443553.1
FGG
fibrinogen gamma chain
chr3_-_129375556 2.67 ENST00000510323.1
TMCC1
transmembrane and coiled-coil domain family 1
chr20_-_43883197 2.55 ENST00000338380.2
SLPI
secretory leukocyte peptidase inhibitor
chr18_-_61329118 2.55 ENST00000332821.8
ENST00000283752.5
SERPINB3
serpin peptidase inhibitor, clade B (ovalbumin), member 3
chr1_+_196621002 2.46 ENST00000367429.4
ENST00000439155.2
CFH
complement factor H
chr6_+_31895467 2.44 ENST00000556679.1
ENST00000456570.1
CFB
CFB
complement factor B
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr1_+_196621156 2.14 ENST00000359637.2
CFH
complement factor H
chr9_+_130911723 2.03 ENST00000277480.2
ENST00000373013.2
ENST00000540948.1
LCN2
lipocalin 2
chr6_+_31895480 1.93 ENST00000418949.2
ENST00000383177.3
ENST00000477310.1
C2
CFB
complement component 2
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr12_-_10007448 1.91 ENST00000538152.1
CLEC2B
C-type lectin domain family 2, member B
chr10_+_63422695 1.87 ENST00000330194.2
ENST00000389639.3
C10orf107
chromosome 10 open reading frame 107
chr1_-_193075180 1.72 ENST00000367440.3
GLRX2
glutaredoxin 2
chr12_-_8693469 1.67 ENST00000545274.1
ENST00000446457.2
CLEC4E
C-type lectin domain family 4, member E
chr11_+_18287721 1.66 ENST00000356524.4
SAA1
serum amyloid A1
chr12_+_65996599 1.65 ENST00000539116.1
ENST00000541391.1
RP11-221N13.3
RP11-221N13.3
chr3_-_4793274 1.64 ENST00000414938.1
EGOT
eosinophil granule ontogeny transcript (non-protein coding)
chr18_-_61311485 1.54 ENST00000436264.1
ENST00000356424.6
ENST00000341074.5
SERPINB4
serpin peptidase inhibitor, clade B (ovalbumin), member 4
chr21_+_35736302 1.52 ENST00000290310.3
KCNE2
potassium voltage-gated channel, Isk-related family, member 2
chr3_-_148939598 1.48 ENST00000455472.3
CP
ceruloplasmin (ferroxidase)
chr12_-_8693539 1.38 ENST00000299663.3
CLEC4E
C-type lectin domain family 4, member E
chr12_-_86230315 1.36 ENST00000361228.3
RASSF9
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
chr7_-_92777606 1.33 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L
sterile alpha motif domain containing 9-like
chr3_-_148939835 1.32 ENST00000264613.6
CP
ceruloplasmin (ferroxidase)
chr2_-_61389240 1.24 ENST00000606876.1
RP11-493E12.1
RP11-493E12.1
chr2_-_113594279 1.20 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
IL1B
interleukin 1, beta
chr19_-_6720686 1.17 ENST00000245907.6
C3
complement component 3
chr11_+_18287801 1.16 ENST00000532858.1
ENST00000405158.2
SAA1
serum amyloid A1
chr11_+_86667117 1.15 ENST00000531827.1
RP11-736K20.6
RP11-736K20.6
chr2_+_228678550 1.14 ENST00000409189.3
ENST00000358813.4
CCL20
chemokine (C-C motif) ligand 20
chr4_+_74606223 1.12 ENST00000307407.3
ENST00000401931.1
IL8
interleukin 8
chr5_-_145483932 1.09 ENST00000311450.4
PLAC8L1
PLAC8-like 1
chr9_+_130911770 1.09 ENST00000372998.1
LCN2
lipocalin 2
chr1_+_52521797 1.07 ENST00000313334.8
BTF3L4
basic transcription factor 3-like 4
chr4_-_15661474 1.03 ENST00000509314.1
ENST00000503196.1
FBXL5
F-box and leucine-rich repeat protein 5
chr19_+_51897742 1.03 ENST00000600765.1
CTD-2616J11.14
CTD-2616J11.14
chr1_+_207277632 1.03 ENST00000421786.1
C4BPA
complement component 4 binding protein, alpha
chr18_-_68004529 1.01 ENST00000578633.1
RP11-484N16.1
RP11-484N16.1
chr2_-_191885686 1.01 ENST00000432058.1
STAT1
signal transducer and activator of transcription 1, 91kDa
chr6_+_126102292 1.00 ENST00000368357.3
NCOA7
nuclear receptor coactivator 7
chr2_-_18770802 0.99 ENST00000416783.1
NT5C1B
5'-nucleotidase, cytosolic IB
chr6_-_113953705 0.96 ENST00000452675.1
RP11-367G18.1
RP11-367G18.1
chr15_-_80263506 0.94 ENST00000335661.6
BCL2A1
BCL2-related protein A1
chr11_-_96123022 0.94 ENST00000542662.1
CCDC82
coiled-coil domain containing 82
chr1_-_89531041 0.93 ENST00000370473.4
GBP1
guanylate binding protein 1, interferon-inducible
chr7_-_33080506 0.93 ENST00000381626.2
ENST00000409467.1
ENST00000449201.1
NT5C3A
5'-nucleotidase, cytosolic IIIA
chr1_-_186649543 0.93 ENST00000367468.5
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr9_+_134001455 0.92 ENST00000531584.1
NUP214
nucleoporin 214kDa
chr7_-_17598506 0.90 ENST00000451792.1
AC017060.1
AC017060.1
chr11_-_104905840 0.86 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
CASP1
caspase 1, apoptosis-related cysteine peptidase
chr10_+_103986085 0.86 ENST00000370005.3
ELOVL3
ELOVL fatty acid elongase 3
chr12_+_7167980 0.86 ENST00000360817.5
ENST00000402681.3
C1S
complement component 1, s subcomponent
chr15_-_55790515 0.85 ENST00000448430.2
ENST00000457155.2
DYX1C1
dyslexia susceptibility 1 candidate 1
chr6_+_76330355 0.83 ENST00000483859.2
SENP6
SUMO1/sentrin specific peptidase 6
chr14_+_96722539 0.82 ENST00000553356.1
BDKRB1
bradykinin receptor B1
chr11_+_105948216 0.82 ENST00000278618.4
AASDHPPT
aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
chr5_-_39219705 0.81 ENST00000351578.6
FYB
FYN binding protein
chrX_+_49644470 0.80 ENST00000508866.2
USP27X
ubiquitin specific peptidase 27, X-linked
chr12_+_32638897 0.79 ENST00000531134.1
FGD4
FYVE, RhoGEF and PH domain containing 4
chr14_+_61449197 0.78 ENST00000533744.2
SLC38A6
solute carrier family 38, member 6
chr9_-_4859260 0.78 ENST00000599351.1
AL158147.2
HCG2011465; Uncharacterized protein
chr2_-_26864228 0.77 ENST00000288861.4
CIB4
calcium and integrin binding family member 4
chr11_-_102668879 0.77 ENST00000315274.6
MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr5_-_39219641 0.76 ENST00000509072.1
ENST00000504542.1
ENST00000505428.1
ENST00000506557.1
FYB
FYN binding protein
chr17_+_1665253 0.75 ENST00000254722.4
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr15_+_71228826 0.74 ENST00000558456.1
ENST00000560158.2
ENST00000558808.1
ENST00000559806.1
ENST00000559069.1
LRRC49
leucine rich repeat containing 49
chr11_-_18270182 0.73 ENST00000528349.1
ENST00000526900.1
ENST00000529528.1
ENST00000414546.2
ENST00000256733.4
SAA2
serum amyloid A2
chr4_+_75230853 0.73 ENST00000244869.2
EREG
epiregulin
chr16_-_87812735 0.72 ENST00000570159.1
RP4-536B24.4
RP4-536B24.4
chr12_+_28410128 0.71 ENST00000381259.1
ENST00000381256.1
CCDC91
coiled-coil domain containing 91
chr14_-_50319758 0.69 ENST00000298310.5
NEMF
nuclear export mediator factor
chr1_+_245133062 0.69 ENST00000366523.1
EFCAB2
EF-hand calcium binding domain 2
chr5_-_180229791 0.68 ENST00000504671.1
ENST00000507384.1
MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr2_-_225362533 0.68 ENST00000451538.1
CUL3
cullin 3
chr2_+_220306745 0.67 ENST00000431523.1
ENST00000396698.1
ENST00000396695.2
SPEG
SPEG complex locus
chr1_-_108231101 0.66 ENST00000544443.1
ENST00000415432.2
VAV3
vav 3 guanine nucleotide exchange factor
chr3_+_136649311 0.65 ENST00000469404.1
ENST00000467911.1
NCK1
NCK adaptor protein 1
chr3_-_42306248 0.64 ENST00000334681.5
CCK
cholecystokinin
chr22_-_40929812 0.64 ENST00000422851.1
MKL1
megakaryoblastic leukemia (translocation) 1
chr9_+_139871948 0.64 ENST00000224167.2
ENST00000457950.1
ENST00000371625.3
ENST00000371623.3
PTGDS
prostaglandin D2 synthase 21kDa (brain)
chr2_+_46769798 0.64 ENST00000238738.4
RHOQ
ras homolog family member Q
chr10_-_115614127 0.63 ENST00000369305.1
DCLRE1A
DNA cross-link repair 1A
chr9_-_117160738 0.62 ENST00000448674.1
RP11-9M16.2
RP11-9M16.2
chr2_+_234590556 0.62 ENST00000373426.3
UGT1A7
UDP glucuronosyltransferase 1 family, polypeptide A7
chr4_+_159593418 0.59 ENST00000507475.1
ENST00000307738.5
ETFDH
electron-transferring-flavoprotein dehydrogenase
chr6_+_117002339 0.59 ENST00000413340.1
ENST00000368564.1
ENST00000356348.1
KPNA5
karyopherin alpha 5 (importin alpha 6)
chr11_-_111944704 0.59 ENST00000532211.1
PIH1D2
PIH1 domain containing 2
chr14_+_95078714 0.58 ENST00000393078.3
ENST00000393080.4
ENST00000467132.1
SERPINA3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr1_+_94883931 0.57 ENST00000394233.2
ENST00000454898.2
ENST00000536817.1
ABCD3
ATP-binding cassette, sub-family D (ALD), member 3
chr2_+_143635067 0.57 ENST00000264170.4
KYNU
kynureninase
chr1_-_117021430 0.57 ENST00000423907.1
ENST00000434879.1
ENST00000443219.1
RP4-655J12.4
RP4-655J12.4
chr1_-_67142710 0.57 ENST00000502413.2
AL139147.1
Uncharacterized protein
chr19_-_17375541 0.56 ENST00000252597.3
USHBP1
Usher syndrome 1C binding protein 1
chr6_+_30749649 0.56 ENST00000422944.1
HCG20
HLA complex group 20 (non-protein coding)
chr2_+_143635222 0.56 ENST00000375773.2
ENST00000409512.1
ENST00000410015.2
KYNU
kynureninase
chr8_+_107593198 0.56 ENST00000517686.1
OXR1
oxidation resistance 1
chr6_-_86353510 0.56 ENST00000444272.1
SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr14_-_23284675 0.56 ENST00000555959.1
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chrX_-_138914394 0.56 ENST00000327569.3
ENST00000361648.2
ENST00000370543.1
ENST00000359686.2
ATP11C
ATPase, class VI, type 11C
chr3_-_158450231 0.56 ENST00000479756.1
RARRES1
retinoic acid receptor responder (tazarotene induced) 1
chr14_-_50319482 0.56 ENST00000546046.1
ENST00000555970.1
ENST00000554626.1
ENST00000545773.1
ENST00000556672.1
NEMF
nuclear export mediator factor
chr4_+_83956237 0.56 ENST00000264389.2
COPS4
COP9 signalosome subunit 4
chr3_+_157154578 0.55 ENST00000295927.3
PTX3
pentraxin 3, long
chr7_+_135347215 0.55 ENST00000507606.1
C7orf73
chromosome 7 open reading frame 73
chr3_-_158390282 0.54 ENST00000264265.3
LXN
latexin
chr6_+_127898312 0.53 ENST00000329722.7
C6orf58
chromosome 6 open reading frame 58
chr8_+_75262612 0.53 ENST00000220822.7
GDAP1
ganglioside induced differentiation associated protein 1
chr3_-_123339343 0.52 ENST00000578202.1
MYLK
myosin light chain kinase
chr1_+_225140372 0.52 ENST00000366848.1
ENST00000439375.2
DNAH14
dynein, axonemal, heavy chain 14
chr5_-_145562147 0.52 ENST00000545646.1
ENST00000274562.9
ENST00000510191.1
ENST00000394434.2
LARS
leucyl-tRNA synthetase
chr13_+_41635617 0.52 ENST00000542082.1
WBP4
WW domain binding protein 4
chr8_-_25315905 0.52 ENST00000221200.4
KCTD9
potassium channel tetramerization domain containing 9
chr1_+_52521957 0.52 ENST00000472944.2
ENST00000484036.1
BTF3L4
basic transcription factor 3-like 4
chr19_+_852291 0.52 ENST00000263621.1
ELANE
elastase, neutrophil expressed
chr1_+_207277590 0.52 ENST00000367070.3
C4BPA
complement component 4 binding protein, alpha
chr13_-_23490508 0.52 ENST00000577004.1
LINC00621
long intergenic non-protein coding RNA 621
chr15_-_63450192 0.51 ENST00000411926.1
RPS27L
ribosomal protein S27-like
chr12_-_76462713 0.51 ENST00000552056.1
NAP1L1
nucleosome assembly protein 1-like 1
chr1_+_94883991 0.50 ENST00000370214.4
ABCD3
ATP-binding cassette, sub-family D (ALD), member 3
chr4_+_83956312 0.50 ENST00000509317.1
ENST00000503682.1
ENST00000511653.1
COPS4
COP9 signalosome subunit 4
chr19_+_6887571 0.50 ENST00000250572.8
ENST00000381407.5
ENST00000312053.4
ENST00000450315.3
ENST00000381404.4
EMR1
egf-like module containing, mucin-like, hormone receptor-like 1
chr19_-_6670128 0.50 ENST00000245912.3
TNFSF14
tumor necrosis factor (ligand) superfamily, member 14
chr13_+_28813645 0.49 ENST00000282391.5
PAN3
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr15_-_55657428 0.48 ENST00000568543.1
CCPG1
cell cycle progression 1
chr6_+_130339710 0.48 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chr3_-_143567262 0.48 ENST00000474151.1
ENST00000316549.6
SLC9A9
solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
chr9_-_117568365 0.47 ENST00000374045.4
TNFSF15
tumor necrosis factor (ligand) superfamily, member 15
chr12_-_12491608 0.47 ENST00000545735.1
MANSC1
MANSC domain containing 1
chr19_-_37019562 0.47 ENST00000523638.1
ZNF260
zinc finger protein 260
chr2_+_201676908 0.46 ENST00000409226.1
ENST00000452790.2
BZW1
basic leucine zipper and W2 domains 1
chr1_+_97187318 0.46 ENST00000609116.1
ENST00000370198.1
ENST00000370197.1
ENST00000426398.2
ENST00000394184.3
PTBP2
polypyrimidine tract binding protein 2
chr7_-_107968921 0.46 ENST00000442580.1
NRCAM
neuronal cell adhesion molecule
chr12_-_79849240 0.46 ENST00000550268.1
RP1-78O14.1
RP1-78O14.1
chr5_+_169011033 0.46 ENST00000513795.1
SPDL1
spindle apparatus coiled-coil protein 1
chr6_+_126240442 0.46 ENST00000448104.1
ENST00000438495.1
ENST00000444128.1
NCOA7
nuclear receptor coactivator 7
chr11_-_105948040 0.45 ENST00000534815.1
KBTBD3
kelch repeat and BTB (POZ) domain containing 3
chr15_-_63449663 0.45 ENST00000439025.1
RPS27L
ribosomal protein S27-like
chr19_-_36004543 0.45 ENST00000339686.3
ENST00000447113.2
ENST00000440396.1
DMKN
dermokine
chrX_+_108779004 0.45 ENST00000218004.1
NXT2
nuclear transport factor 2-like export factor 2
chr1_-_163172625 0.44 ENST00000527988.1
ENST00000531476.1
ENST00000530507.1
RGS5
regulator of G-protein signaling 5
chrX_-_71525742 0.44 ENST00000450875.1
ENST00000417400.1
ENST00000431381.1
ENST00000445983.1
CITED1
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
chr6_+_149539053 0.44 ENST00000451095.1
RP1-111D6.3
RP1-111D6.3
chr20_+_12989596 0.44 ENST00000434210.1
ENST00000399002.2
SPTLC3
serine palmitoyltransferase, long chain base subunit 3
chr7_-_100239132 0.43 ENST00000223051.3
ENST00000431692.1
TFR2
transferrin receptor 2
chr4_-_184580304 0.43 ENST00000510968.1
ENST00000512740.1
ENST00000327570.9
RWDD4
RWD domain containing 4
chr18_-_29340827 0.43 ENST00000269205.5
SLC25A52
solute carrier family 25, member 52
chr1_+_52521928 0.42 ENST00000489308.2
BTF3L4
basic transcription factor 3-like 4
chr12_+_67663056 0.42 ENST00000545606.1
CAND1
cullin-associated and neddylation-dissociated 1
chr5_-_36152031 0.42 ENST00000296603.4
LMBRD2
LMBR1 domain containing 2
chr12_+_27849378 0.41 ENST00000310791.2
REP15
RAB15 effector protein
chr2_+_11295624 0.41 ENST00000402361.1
ENST00000428481.1
PQLC3
PQ loop repeat containing 3
chr4_+_78079450 0.41 ENST00000395640.1
ENST00000512918.1
CCNG2
cyclin G2
chr10_-_128110441 0.41 ENST00000456514.1
LINC00601
long intergenic non-protein coding RNA 601
chrX_+_591524 0.41 ENST00000554971.1
ENST00000381575.1
SHOX
short stature homeobox
chr13_-_33112899 0.41 ENST00000267068.3
ENST00000357505.6
ENST00000399396.3
N4BP2L2
NEDD4 binding protein 2-like 2
chr12_+_100897130 0.41 ENST00000551379.1
ENST00000188403.7
ENST00000551184.1
NR1H4
nuclear receptor subfamily 1, group H, member 4
chr12_+_11081828 0.40 ENST00000381847.3
ENST00000396400.3
PRH2
proline-rich protein HaeIII subfamily 2
chr4_+_186347388 0.39 ENST00000511138.1
ENST00000511581.1
C4orf47
chromosome 4 open reading frame 47
chr17_-_9939854 0.39 ENST00000584146.2
GAS7
growth arrest-specific 7
chr1_+_93913665 0.39 ENST00000271234.7
ENST00000370256.4
ENST00000260506.8
FNBP1L
formin binding protein 1-like
chr6_+_27782788 0.39 ENST00000359465.4
HIST1H2BM
histone cluster 1, H2bm
chr5_+_49962772 0.39 ENST00000281631.5
ENST00000513738.1
ENST00000503665.1
ENST00000514067.2
ENST00000503046.1
PARP8
poly (ADP-ribose) polymerase family, member 8
chr12_+_7456880 0.39 ENST00000399422.4
ACSM4
acyl-CoA synthetase medium-chain family member 4
chr14_-_23285069 0.38 ENST00000554758.1
ENST00000397528.4
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr13_-_33112956 0.38 ENST00000505213.1
N4BP2L2
NEDD4 binding protein 2-like 2
chr5_-_137878887 0.38 ENST00000507939.1
ENST00000572514.1
ENST00000499810.2
ENST00000360541.5
ETF1
eukaryotic translation termination factor 1
chr19_+_840963 0.38 ENST00000234347.5
PRTN3
proteinase 3
chr17_-_67264947 0.38 ENST00000586811.1
ABCA5
ATP-binding cassette, sub-family A (ABC1), member 5
chr13_+_78109804 0.37 ENST00000535157.1
SCEL
sciellin
chrX_+_16141667 0.37 ENST00000380289.2
GRPR
gastrin-releasing peptide receptor
chr1_+_94884023 0.37 ENST00000315713.5
ABCD3
ATP-binding cassette, sub-family D (ALD), member 3
chr3_+_88188254 0.37 ENST00000309495.5
ZNF654
zinc finger protein 654
chr1_-_54304212 0.37 ENST00000540001.1
NDC1
NDC1 transmembrane nucleoporin
chr1_+_78383813 0.36 ENST00000342754.5
NEXN
nexilin (F actin binding protein)
chr2_-_152146385 0.36 ENST00000414946.1
ENST00000243346.5
NMI
N-myc (and STAT) interactor
chr7_+_26191809 0.35 ENST00000056233.3
NFE2L3
nuclear factor, erythroid 2-like 3
chr11_-_72852320 0.35 ENST00000422375.1
FCHSD2
FCH and double SH3 domains 2
chr12_+_27398584 0.35 ENST00000543246.1
STK38L
serine/threonine kinase 38 like
chr4_+_86699834 0.35 ENST00000395183.2
ARHGAP24
Rho GTPase activating protein 24
chr1_+_244816237 0.35 ENST00000302550.11
DESI2
desumoylating isopeptidase 2
chr1_-_238108575 0.34 ENST00000604646.1
MTRNR2L11
MT-RNR2-like 11 (pseudogene)
chr19_-_42927251 0.34 ENST00000597001.1
LIPE
lipase, hormone-sensitive
chr9_-_125027079 0.34 ENST00000417201.3
RBM18
RNA binding motif protein 18
chr3_+_124303512 0.34 ENST00000454902.1
KALRN
kalirin, RhoGEF kinase
chr1_+_114473350 0.34 ENST00000503968.1
HIPK1
homeodomain interacting protein kinase 1
chr11_-_105948129 0.34 ENST00000526793.1
KBTBD3
kelch repeat and BTB (POZ) domain containing 3
chr9_-_34665983 0.34 ENST00000416454.1
ENST00000544078.2
ENST00000421828.2
ENST00000423809.1
RP11-195F19.5
HCG2040265, isoform CRA_a; Uncharacterized protein; cDNA FLJ50015
chr14_-_23285011 0.33 ENST00000397532.3
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr14_+_39703084 0.33 ENST00000553728.1
RP11-407N17.3
cTAGE family member 5 isoform 4
chr12_-_95510743 0.32 ENST00000551521.1
FGD6
FYVE, RhoGEF and PH domain containing 6
chr2_+_33359687 0.32 ENST00000402934.1
ENST00000404525.1
ENST00000407925.1
LTBP1
latent transforming growth factor beta binding protein 1
chr11_-_33913708 0.32 ENST00000257818.2
LMO2
LIM domain only 2 (rhombotin-like 1)
chr12_+_12966250 0.32 ENST00000352940.4
ENST00000358007.3
ENST00000544400.1
DDX47
DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
chr19_+_17862274 0.32 ENST00000596536.1
ENST00000593870.1
ENST00000598086.1
ENST00000598932.1
ENST00000595023.1
ENST00000594068.1
ENST00000596507.1
ENST00000595033.1
ENST00000597718.1
FCHO1
FCH domain only 1
chr12_+_20963647 0.32 ENST00000381545.3
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr11_+_18433840 0.31 ENST00000541669.1
ENST00000280704.4
LDHC
lactate dehydrogenase C
chr8_+_27184320 0.31 ENST00000522517.1
PTK2B
protein tyrosine kinase 2 beta
chr5_-_75008244 0.31 ENST00000510798.1
ENST00000446329.2
POC5
POC5 centriolar protein
chr1_-_23340400 0.31 ENST00000440767.2
C1orf234
chromosome 1 open reading frame 234
chrX_-_16730688 0.31 ENST00000359276.4
CTPS2
CTP synthase 2

Network of associatons between targets according to the STRING database.

First level regulatory network of CEBPA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.5 GO:0035425 autocrine signaling(GO:0035425)
0.6 3.1 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.6 1.7 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.6 10.1 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.4 1.1 GO:0045362 interleukin-1 biosynthetic process(GO:0042222) regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.4 1.4 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.3 0.9 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.3 1.5 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.3 1.1 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.3 1.0 GO:0072308 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.2 1.5 GO:0030450 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.2 0.7 GO:1903676 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.2 1.1 GO:0001878 response to yeast(GO:0001878)
0.2 1.2 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.2 0.5 GO:0006429 glutaminyl-tRNA aminoacylation(GO:0006425) leucyl-tRNA aminoacylation(GO:0006429)
0.2 1.7 GO:0042262 DNA protection(GO:0042262)
0.2 0.9 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.1 0.7 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.1 1.3 GO:0000821 regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
0.1 0.9 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.1 0.4 GO:0030264 nuclear fragmentation involved in apoptotic nuclear change(GO:0030264)
0.1 0.5 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.1 0.5 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.1 0.4 GO:0071790 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.1 0.8 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.1 3.2 GO:0031639 plasminogen activation(GO:0031639)
0.1 1.2 GO:0051552 flavone metabolic process(GO:0051552)
0.1 2.0 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 0.3 GO:0019516 lactate oxidation(GO:0019516)
0.1 0.7 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.1 0.7 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 0.4 GO:2001248 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.1 0.5 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1 2.8 GO:0006825 copper ion transport(GO:0006825)
0.1 0.4 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745) reverse cholesterol transport(GO:0043691)
0.1 0.8 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.1 0.3 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 2.6 GO:0019731 antibacterial humoral response(GO:0019731)
0.1 0.7 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.1 0.6 GO:0035624 receptor transactivation(GO:0035624)
0.1 0.5 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.6 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.4 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.1 2.8 GO:0050716 positive regulation of interleukin-1 secretion(GO:0050716)
0.1 0.2 GO:1904586 response to putrescine(GO:1904585) cellular response to putrescine(GO:1904586) hepatocyte dedifferentiation(GO:1990828)
0.1 0.3 GO:0046110 xanthine metabolic process(GO:0046110)
0.1 0.4 GO:0036343 psychomotor behavior(GO:0036343)
0.1 0.6 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.1 0.9 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.7 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 0.2 GO:1901340 negative regulation of store-operated calcium channel activity(GO:1901340)
0.1 0.7 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.1 0.6 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 0.9 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 0.3 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 0.6 GO:0032096 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
0.1 0.2 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.1 0.4 GO:0071104 response to interleukin-9(GO:0071104)
0.1 0.2 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.1 0.2 GO:0008057 eye pigment granule organization(GO:0008057)
0.1 1.1 GO:0000338 protein deneddylation(GO:0000338)
0.1 0.3 GO:0010752 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.1 0.6 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 0.6 GO:0002329 pre-B cell differentiation(GO:0002329)
0.1 0.4 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.1 GO:0051866 general adaptation syndrome(GO:0051866)
0.0 0.2 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.0 0.4 GO:0045357 interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357)
0.0 0.3 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0 0.2 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.0 0.1 GO:0010901 regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
0.0 0.8 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 2.2 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.6 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.4 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.0 GO:0046668 regulation of retinal cell programmed cell death(GO:0046668)
0.0 1.0 GO:0006553 lysine metabolic process(GO:0006553)
0.0 0.4 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.6 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.1 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.0 0.2 GO:0015960 diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966)
0.0 0.7 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.4 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 1.0 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.0 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.0 0.2 GO:1903613 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.0 1.3 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.5 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 2.9 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.2 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.1 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.2 GO:0032960 regulation of inositol trisphosphate biosynthetic process(GO:0032960)
0.0 0.1 GO:0006711 estrogen catabolic process(GO:0006711)
0.0 0.6 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.1 GO:0061528 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.0 0.2 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.4 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.4 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.0 0.1 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
0.0 0.2 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.0 0.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.2 GO:0019557 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.1 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.0 0.2 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 0.3 GO:0060235 embryonic retina morphogenesis in camera-type eye(GO:0060059) lens induction in camera-type eye(GO:0060235)
0.0 0.1 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.0 0.2 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.5 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 2.4 GO:0002292 T cell differentiation involved in immune response(GO:0002292)
0.0 0.2 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.0 0.2 GO:0008228 opsonization(GO:0008228)
0.0 0.4 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.0 0.5 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.4 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.5 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.6 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.0 0.4 GO:1903319 positive regulation of protein maturation(GO:1903319)
0.0 0.5 GO:0050961 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.2 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.1 GO:0043387 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.0 0.3 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.7 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.3 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.3 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.8 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.0 0.1 GO:1901297 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.3 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.0 GO:0006670 sphingosine metabolic process(GO:0006670)
0.0 0.2 GO:0097338 response to clozapine(GO:0097338)
0.0 0.2 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.0 0.9 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.1 GO:0097112 gamma-aminobutyric acid receptor clustering(GO:0097112)
0.0 0.1 GO:0060694 regulation of cholesterol transporter activity(GO:0060694) response to metformin(GO:1901558) negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.0 0.3 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.4 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.8 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.2 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 0.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.1 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.2 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.3 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.2 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.2 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.2 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.2 GO:0006105 succinate metabolic process(GO:0006105)
0.0 0.1 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.1 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.4 GO:0006633 fatty acid biosynthetic process(GO:0006633)
0.0 0.4 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.5 GO:0030890 positive regulation of B cell proliferation(GO:0030890)
0.0 0.2 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.3 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.0 0.5 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.1 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.4 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.2 2.8 GO:0005577 fibrinogen complex(GO:0005577)
0.2 0.9 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.1 2.8 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.1 0.5 GO:0031251 PAN complex(GO:0031251)
0.1 0.4 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.1 0.5 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.1 14.9 GO:0072562 blood microparticle(GO:0072562)
0.1 0.3 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.1 0.6 GO:0097452 GAIT complex(GO:0097452)
0.1 1.6 GO:0043203 axon hillock(GO:0043203)
0.1 0.7 GO:0005827 polar microtubule(GO:0005827)
0.1 1.4 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 0.2 GO:0045273 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 1.0 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 4.1 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.1 GO:0005602 complement component C1 complex(GO:0005602)
0.0 0.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.4 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.3 GO:0030891 VCB complex(GO:0030891)
0.0 0.7 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.1 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.0 0.1 GO:0016935 glycine-gated chloride channel complex(GO:0016935)
0.0 0.2 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 0.4 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.5 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.7 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.7 GO:0042101 T cell receptor complex(GO:0042101)
0.0 2.9 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.2 GO:0097486 multivesicular body lumen(GO:0097486)
0.0 0.2 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 0.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.3 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 2.6 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.2 GO:0033263 CORVET complex(GO:0033263)
0.0 0.6 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 1.1 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.4 GO:0043194 axon initial segment(GO:0043194)
0.0 0.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.6 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 0.8 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.6 GO:0001533 cornified envelope(GO:0001533)
0.0 1.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.5 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.4 2.8 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.3 0.8 GO:0004947 bradykinin receptor activity(GO:0004947)
0.2 1.4 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.2 1.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.2 1.7 GO:0030614 oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614)
0.2 4.6 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.2 0.6 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.2 1.1 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.2 0.9 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.2 0.5 GO:0004823 glutamine-tRNA ligase activity(GO:0004819) leucine-tRNA ligase activity(GO:0004823)
0.2 0.6 GO:0032427 GBD domain binding(GO:0032427)
0.1 0.7 GO:0050436 microfibril binding(GO:0050436)
0.1 5.2 GO:0001848 complement binding(GO:0001848)
0.1 0.7 GO:0031208 POZ domain binding(GO:0031208)
0.1 0.7 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 0.4 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.1 0.5 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.1 0.3 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.1 1.5 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.1 0.4 GO:0004998 transferrin receptor activity(GO:0004998)
0.1 0.4 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.1 1.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 0.6 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 0.2 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.1 0.9 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.2 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.1 1.3 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.1 1.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 8.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.2 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.1 0.2 GO:0004397 histidine ammonia-lyase activity(GO:0004397)
0.1 0.3 GO:0003883 CTP synthase activity(GO:0003883)
0.1 0.3 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 3.0 GO:0042056 chemoattractant activity(GO:0042056)
0.1 0.8 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.1 0.7 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 1.5 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.1 0.4 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.1 0.4 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.3 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 0.9 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.5 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.1 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386)
0.0 0.6 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.4 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.9 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0032551 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.0 0.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.5 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.5 GO:0050693 LBD domain binding(GO:0050693)
0.0 1.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.3 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.0 0.2 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.7 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.3 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 1.9 GO:0005501 retinoid binding(GO:0005501)
0.0 0.9 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.1 GO:0003867 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.0 1.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.6 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.2 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.2 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.2 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.3 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.6 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.5 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.6 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 4.1 GO:0005506 iron ion binding(GO:0005506)
0.0 0.1 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.0 0.2 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.3 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.2 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.2 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.6 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.1 GO:0005057 receptor signaling protein activity(GO:0005057)
0.0 1.2 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.2 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.6 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.2 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.3 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.0 0.1 GO:0033691 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828) sialic acid binding(GO:0033691)
0.0 0.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.9 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.3 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.6 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.4 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 0.6 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.2 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.4 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.1 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 4.7 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.8 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.2 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.4 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 1.0 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.1 1.7 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 2.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.5 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 3.5 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.1 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.9 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.8 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 8.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.9 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.9 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 2.6 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.4 PID CD40 PATHWAY CD40/CD40L signaling
0.0 4.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.5 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.6 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.3 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.9 PID BCR 5PATHWAY BCR signaling pathway
0.0 1.8 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.6 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.9 PID INSULIN PATHWAY Insulin Pathway
0.0 1.5 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.6 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.3 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 12.0 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.2 1.0 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 2.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 2.8 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 3.0 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 0.8 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 1.0 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 1.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 1.0 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 1.9 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 1.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.8 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.3 REACTOME OPSINS Genes involved in Opsins
0.0 1.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 1.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.2 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.4 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.7 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 1.4 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.2 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.7 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 1.9 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.5 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.9 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.4 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 1.1 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 1.3 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.2 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.6 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.9 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds