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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for BACH1_NFE2_NFE2L2

Z-value: 1.29

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Transcription factors associated with BACH1_NFE2_NFE2L2

Gene Symbol Gene ID Gene Info
ENSG00000156273.11 BTB domain and CNC homolog 1
ENSG00000123405.9 nuclear factor, erythroid 2
ENSG00000116044.11 nuclear factor, erythroid 2 like 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFE2L2hg19_v2_chr2_-_178257401_178257432-0.843.8e-02Click!
BACH1hg19_v2_chr21_+_30671189_30671207-0.777.2e-02Click!
NFE2hg19_v2_chr12_-_54694758_54694805-0.424.0e-01Click!

Activity profile of BACH1_NFE2_NFE2L2 motif

Sorted Z-values of BACH1_NFE2_NFE2L2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_-_1429010 2.75 ENST00000513783.1
unkempt family zinc finger-like
chr4_+_22999152 1.56 ENST00000511453.1
RP11-412P11.1
chr5_+_35852797 1.49 ENST00000508941.1
interleukin 7 receptor
chr11_+_62475130 0.90 ENST00000294117.5
guanine nucleotide binding protein (G protein), gamma 3
chr16_+_83986827 0.83 ENST00000393306.1
ENST00000565123.1
oxidative stress induced growth inhibitor 1
chr16_-_1429627 0.79 ENST00000248104.7
unkempt family zinc finger-like
chr5_+_179247759 0.79 ENST00000389805.4
ENST00000504627.1
ENST00000402874.3
ENST00000510187.1
sequestosome 1
chr16_+_30077098 0.79 ENST00000395240.3
ENST00000566846.1
aldolase A, fructose-bisphosphate
chr4_-_987164 0.75 ENST00000398520.2
solute carrier family 26 (anion exchanger), member 1
chr10_-_71892555 0.72 ENST00000307864.1
apoptosis-inducing factor, mitochondrion-associated, 2
chr17_+_80317121 0.71 ENST00000333437.4
testis expressed 19
chr12_+_10365082 0.69 ENST00000545859.1
GABA(A) receptor-associated protein like 1
chr2_+_54342533 0.65 ENST00000406041.1
acylphosphatase 2, muscle type
chr16_-_1429674 0.64 ENST00000403703.1
ENST00000397464.1
ENST00000402641.2
unkempt family zinc finger-like
chr2_-_220083076 0.62 ENST00000295750.4
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chrX_+_33760127 0.60 ENST00000445233.1
RP11-305F18.1
chr10_-_76868931 0.59 ENST00000372700.3
ENST00000473072.2
ENST00000491677.2
ENST00000607131.1
ENST00000372702.3
dual specificity phosphatase 13
chr1_-_158656488 0.59 ENST00000368147.4
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr5_-_175965008 0.59 ENST00000537487.1
ring finger protein 44
chr19_+_18699599 0.57 ENST00000450195.2
chromosome 19 open reading frame 60
chr16_+_30077055 0.54 ENST00000564595.2
ENST00000569798.1
aldolase A, fructose-bisphosphate
chr17_-_39769005 0.53 ENST00000301653.4
ENST00000593067.1
keratin 16
chr5_-_173173171 0.53 ENST00000517733.1
ENST00000518902.1
CTB-43E15.3
chr22_-_19466643 0.53 ENST00000474226.1
ubiquitin fusion degradation 1 like (yeast)
chr12_+_10365404 0.53 ENST00000266458.5
ENST00000421801.2
ENST00000544284.1
ENST00000545047.1
ENST00000543602.1
ENST00000545887.1
GABA(A) receptor-associated protein like 1
chr19_+_18699535 0.52 ENST00000358607.6
chromosome 19 open reading frame 60
chr2_-_220117867 0.52 ENST00000456818.1
ENST00000447205.1
tubulin, alpha 4a
chr9_+_140083099 0.47 ENST00000322310.5
Sjogren syndrome nuclear autoantigen 1
chr8_+_125283924 0.45 ENST00000517482.1
RP11-383J24.1
chr3_+_183903811 0.44 ENST00000429586.2
ENST00000292808.5
ATP-binding cassette, sub-family F (GCN20), member 3
chr17_-_79881408 0.43 ENST00000392366.3
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
chr16_+_57662596 0.42 ENST00000567397.1
ENST00000568979.1
G protein-coupled receptor 56
chr17_-_3794021 0.42 ENST00000381769.2
calcium/calmodulin-dependent protein kinase kinase 1, alpha
chr22_+_20008646 0.42 ENST00000401833.1
transport and golgi organization 2 homolog (Drosophila)
chr19_-_10613421 0.41 ENST00000393623.2
kelch-like ECH-associated protein 1
chr11_+_60699222 0.41 ENST00000536409.1
transmembrane protein 132A
chr17_+_79935464 0.40 ENST00000581647.1
ENST00000580534.1
ENST00000579684.1
alveolar soft part sarcoma chromosome region, candidate 1
chr10_-_127505167 0.39 ENST00000368786.1
uroporphyrinogen III synthase
chr9_+_141107506 0.38 ENST00000446912.2
family with sequence similarity 157, member B
chr12_-_122238464 0.38 ENST00000546227.1
ras homolog family member F (in filopodia)
chr11_-_111794446 0.38 ENST00000527950.1
crystallin, alpha B
chr7_-_86849836 0.38 ENST00000455575.1
transmembrane protein 243, mitochondrial
chr3_+_69915363 0.38 ENST00000451708.1
microphthalmia-associated transcription factor
chrX_+_153769409 0.37 ENST00000440286.1
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr20_+_24929866 0.35 ENST00000480798.1
ENST00000376835.2
cystatin F (leukocystatin)
chr11_-_67141640 0.35 ENST00000533438.1
cardiotrophin-like cytokine factor 1
chr11_+_72983246 0.34 ENST00000393590.2
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr16_+_57662419 0.34 ENST00000388812.4
ENST00000538815.1
ENST00000456916.1
ENST00000567154.1
ENST00000388813.5
ENST00000562558.1
ENST00000566271.2
G protein-coupled receptor 56
chr6_-_3157760 0.34 ENST00000333628.3
tubulin, beta 2A class IIa
chr19_+_49467232 0.34 ENST00000599784.1
ENST00000594305.1
CTD-2639E6.9
chrX_+_153770421 0.33 ENST00000369609.5
ENST00000369607.1
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr4_-_987217 0.33 ENST00000361661.2
ENST00000398516.2
solute carrier family 26 (anion exchanger), member 1
chr18_+_11857439 0.33 ENST00000602628.1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chrX_-_154563889 0.33 ENST00000369449.2
ENST00000321926.4
chloride intracellular channel 2
chr14_-_103589246 0.33 ENST00000558224.1
ENST00000560742.1
long intergenic non-protein coding RNA 677
chr11_-_2924720 0.33 ENST00000455942.2
solute carrier family 22 (organic cation transporter), member 18 antisense
chr9_-_140082983 0.32 ENST00000323927.2
anaphase promoting complex subunit 2
chr3_+_184016986 0.32 ENST00000417952.1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
chr15_-_51397473 0.32 ENST00000327536.5
tumor necrosis factor, alpha-induced protein 8-like 3
chr6_-_28321827 0.32 ENST00000444081.1
zinc finger and SCAN domain containing 31
chr6_-_56819385 0.31 ENST00000370754.5
ENST00000449297.2
dystonin
chr19_-_10613862 0.31 ENST00000592055.1
kelch-like ECH-associated protein 1
chr12_+_56075330 0.31 ENST00000394252.3
methyltransferase like 7B
chr10_-_76995675 0.31 ENST00000469299.1
catechol-O-methyltransferase domain containing 1
chr9_-_116840728 0.30 ENST00000265132.3
alpha-1-microglobulin/bikunin precursor
chr12_+_79357815 0.30 ENST00000547046.1
synaptotagmin I
chr8_-_144413981 0.30 ENST00000522041.1
topoisomerase (DNA) I, mitochondrial
chr17_-_8301132 0.29 ENST00000399398.2
ring finger protein 222
chr3_-_186262166 0.29 ENST00000307944.5
crystallin, gamma S
chr11_+_67351019 0.29 ENST00000398606.3
glutathione S-transferase pi 1
chr19_-_46285646 0.28 ENST00000458663.2
dystrophia myotonica-protein kinase
chr11_-_119066545 0.28 ENST00000415318.1
coiled-coil domain containing 153
chr5_-_175964366 0.28 ENST00000274811.4
ring finger protein 44
chr3_+_184038234 0.27 ENST00000427607.1
ENST00000457456.1
eukaryotic translation initiation factor 4 gamma, 1
chr6_-_39902185 0.27 ENST00000373195.3
ENST00000308559.7
ENST00000373188.2
molybdenum cofactor synthesis 1
chr19_-_10613361 0.26 ENST00000591039.1
ENST00000591419.1
kelch-like ECH-associated protein 1
chr19_-_39390212 0.26 ENST00000437828.1
sirtuin 2
chr10_-_6019984 0.26 ENST00000525219.2
interleukin 15 receptor, alpha
chr10_-_76995769 0.26 ENST00000372538.3
catechol-O-methyltransferase domain containing 1
chr10_+_127661942 0.25 ENST00000417114.1
ENST00000445510.1
ENST00000368691.1
fibronectin type III and ankyrin repeat domains 1
chr16_+_8736232 0.25 ENST00000562973.1
methyltransferase like 22
chr8_+_94752349 0.25 ENST00000391680.1
RBM12B antisense RNA 1
chr8_-_145025044 0.25 ENST00000322810.4
plectin
chrX_+_56590002 0.25 ENST00000338222.5
ubiquilin 2
chr14_-_95942173 0.24 ENST00000334258.5
ENST00000557275.1
ENST00000553340.1
spectrin repeat containing, nuclear envelope family member 3
chr7_+_101460882 0.24 ENST00000292535.7
ENST00000549414.2
ENST00000550008.2
ENST00000546411.2
ENST00000556210.1
cut-like homeobox 1
chr3_-_46608010 0.24 ENST00000395905.3
leucine rich repeat containing 2
chr7_+_100026406 0.24 ENST00000414441.1
methylphosphate capping enzyme
chr10_-_99531709 0.24 ENST00000266066.3
secreted frizzled-related protein 5
chr20_+_42839600 0.24 ENST00000439943.1
ENST00000437730.1
OSER1 antisense RNA 1 (head to head)
chr22_-_45608237 0.24 ENST00000492273.1
KIAA0930
chr16_+_80574854 0.24 ENST00000305904.6
ENST00000568035.1
dynein, light chain, roadblock-type 2
chr5_+_42756903 0.24 ENST00000361970.5
ENST00000388827.4
coiled-coil domain containing 152
chr7_+_139528952 0.24 ENST00000416849.2
ENST00000436047.2
ENST00000414508.2
ENST00000448866.1
thromboxane A synthase 1 (platelet)
chr8_-_145013711 0.24 ENST00000345136.3
plectin
chr11_+_72281681 0.24 ENST00000450804.3
RP11-169D4.1
chr16_+_30418910 0.24 ENST00000566625.1
zinc finger protein 771
chr6_+_56819895 0.23 ENST00000370748.3
BEN domain containing 6
chr8_+_87111059 0.23 ENST00000285393.3
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
chr2_-_190446738 0.23 ENST00000427419.1
ENST00000455320.1
solute carrier family 40 (iron-regulated transporter), member 1
chr18_-_55253989 0.22 ENST00000262093.5
ferrochelatase
chr10_-_105437909 0.22 ENST00000540321.1
SH3 and PX domains 2A
chr20_+_42839722 0.22 ENST00000442383.1
ENST00000435163.1
OSER1 antisense RNA 1 (head to head)
chr5_-_131879205 0.22 ENST00000231454.1
interleukin 5 (colony-stimulating factor, eosinophil)
chr22_-_39636914 0.22 ENST00000381551.4
platelet-derived growth factor beta polypeptide
chr10_-_13544945 0.22 ENST00000378605.3
ENST00000341083.3
BEN domain containing 7
chr12_-_120687948 0.22 ENST00000458477.2
paxillin
chr3_+_184038073 0.22 ENST00000428387.1
ENST00000434061.2
eukaryotic translation initiation factor 4 gamma, 1
chr1_-_12677714 0.22 ENST00000376223.2
dehydrogenase/reductase (SDR family) member 3
chr7_+_139529040 0.22 ENST00000455353.1
ENST00000458722.1
ENST00000411653.1
thromboxane A synthase 1 (platelet)
chr8_-_30585294 0.21 ENST00000546342.1
ENST00000541648.1
ENST00000537535.1
glutathione reductase
chr20_+_48909240 0.21 ENST00000371639.3
RP11-290F20.1
chr15_-_76304731 0.21 ENST00000394907.3
neuregulin 4
chr6_+_147981838 0.21 ENST00000427015.1
ENST00000432506.1
RP11-307P5.1
chr14_-_81687575 0.21 ENST00000434192.2
general transcription factor IIA, 1, 19/37kDa
chrX_+_22056165 0.21 ENST00000535894.1
phosphate regulating endopeptidase homolog, X-linked
chr10_-_71906342 0.21 ENST00000287078.6
ENST00000335494.5
trypsin domain containing 1
chr19_+_6531010 0.20 ENST00000245817.3
tumor necrosis factor (ligand) superfamily, member 9
chr22_+_42196666 0.20 ENST00000402061.3
ENST00000255784.5
coiled-coil domain containing 134
chr11_-_47447970 0.20 ENST00000298852.3
ENST00000530912.1
proteasome (prosome, macropain) 26S subunit, ATPase, 3
chr2_+_207804278 0.20 ENST00000272852.3
carboxypeptidase O
chr6_-_39902160 0.20 ENST00000340692.5
molybdenum cofactor synthesis 1
chr17_+_21191341 0.20 ENST00000526076.2
ENST00000361818.5
ENST00000316920.6
mitogen-activated protein kinase kinase 3
chr20_-_43280361 0.20 ENST00000372874.4
adenosine deaminase
chr11_+_67351213 0.19 ENST00000398603.1
glutathione S-transferase pi 1
chr22_+_29702572 0.19 ENST00000407647.2
ENST00000416823.1
ENST00000428622.1
growth arrest-specific 2 like 1
chr3_+_126423045 0.19 ENST00000290913.3
ENST00000508789.1
coiled-coil-helix-coiled-coil-helix domain containing 6
chr19_+_50094866 0.19 ENST00000418929.2
proline rich 12
chr20_-_1306351 0.19 ENST00000381812.1
syndecan binding protein (syntenin) 2
chr22_+_45072958 0.19 ENST00000403581.1
proline rich 5 (renal)
chr15_-_83240783 0.19 ENST00000568994.1
cytoplasmic polyadenylation element binding protein 1
chr9_+_116917807 0.19 ENST00000356083.3
collagen, type XXVII, alpha 1
chr6_+_41604747 0.19 ENST00000419164.1
ENST00000373051.2
MyoD family inhibitor
chr18_-_55253900 0.19 ENST00000585747.1
ENST00000592699.1
ferrochelatase
chr16_+_89988259 0.19 ENST00000554444.1
ENST00000556565.1
Tubulin beta-3 chain
chr11_-_102826434 0.19 ENST00000340273.4
ENST00000260302.3
matrix metallopeptidase 13 (collagenase 3)
chr12_+_6644443 0.19 ENST00000396858.1
glyceraldehyde-3-phosphate dehydrogenase
chr11_+_72983450 0.19 ENST00000536225.1
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr16_-_69760409 0.19 ENST00000561500.1
ENST00000439109.2
ENST00000564043.1
ENST00000379046.2
ENST00000379047.3
NAD(P)H dehydrogenase, quinone 1
chr10_-_21786179 0.18 ENST00000377113.5
cancer susceptibility candidate 10
chr17_-_15469590 0.18 ENST00000312127.2
CMT duplicated region transcript 1; Uncharacterized protein
chr9_-_35071960 0.18 ENST00000417448.1
valosin containing protein
chr9_+_116267536 0.18 ENST00000374136.1
regulator of G-protein signaling 3
chr3_+_14474178 0.18 ENST00000452775.1
solute carrier family 6 (neurotransmitter transporter), member 6
chr22_-_19466454 0.18 ENST00000494054.1
ubiquitin fusion degradation 1 like (yeast)
chr16_+_57662527 0.18 ENST00000563374.1
ENST00000568234.1
ENST00000565770.1
ENST00000564338.1
ENST00000566164.1
G protein-coupled receptor 56
chr16_+_12059091 0.18 ENST00000562385.1
tumor necrosis factor receptor superfamily, member 17
chr11_-_47447767 0.18 ENST00000530651.1
ENST00000524447.2
ENST00000531051.2
ENST00000526993.1
ENST00000602866.1
proteasome (prosome, macropain) 26S subunit, ATPase, 3
chr19_-_39390440 0.18 ENST00000249396.7
ENST00000414941.1
ENST00000392081.2
sirtuin 2
chr16_+_67261008 0.18 ENST00000304800.9
ENST00000563953.1
ENST00000565201.1
transmembrane protein 208
chr4_+_87928413 0.18 ENST00000544085.1
AF4/FMR2 family, member 1
chr12_-_58026451 0.18 ENST00000552350.1
ENST00000548888.1
beta-1,4-N-acetyl-galactosaminyl transferase 1
chr19_-_39390350 0.18 ENST00000447739.1
ENST00000358931.5
ENST00000407552.1
sirtuin 2
chr12_+_10366223 0.18 ENST00000545290.1
GABA(A) receptor-associated protein like 1
chr11_-_128894053 0.18 ENST00000392657.3
Rho GTPase activating protein 32
chr12_+_10366016 0.17 ENST00000546017.1
ENST00000535576.1
ENST00000539170.1
GABA(A) receptor-associated protein like 1
chr16_+_66442411 0.17 ENST00000499966.1
long intergenic non-protein coding RNA 920
chr9_+_35538616 0.17 ENST00000455600.1
RUN and SH3 domain containing 2
chr18_+_21452804 0.17 ENST00000269217.6
laminin, alpha 3
chr14_-_24732368 0.17 ENST00000544573.1
transglutaminase 1
chr18_+_21594384 0.17 ENST00000584250.1
tetratricopeptide repeat domain 39C
chr4_+_146402346 0.17 ENST00000514778.1
ENST00000507594.1
SMAD family member 1
chr2_+_71680852 0.17 ENST00000409762.1
ENST00000409582.3
ENST00000429174.2
ENST00000413539.2
ENST00000258104.3
dysferlin
chr18_-_72920372 0.16 ENST00000581620.1
ENST00000582437.1
zinc binding alcohol dehydrogenase domain containing 2
chr1_-_214638146 0.16 ENST00000543945.1
protein tyrosine phosphatase, non-receptor type 14
chr8_+_21914348 0.16 ENST00000520174.1
dematin actin binding protein
chr19_-_10444188 0.16 ENST00000293677.6
ribonucleoprotein, PTB-binding 1
chr14_-_75735986 0.16 ENST00000553510.1
Uncharacterized protein
chrX_+_153769446 0.16 ENST00000422680.1
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr3_+_69915385 0.16 ENST00000314589.5
microphthalmia-associated transcription factor
chr7_+_44040488 0.16 ENST00000258704.3
speedy/RINGO cell cycle regulator family member E1
chr17_-_79604075 0.16 ENST00000374747.5
ENST00000539314.1
ENST00000331134.6
nuclear protein localization 4 homolog (S. cerevisiae)
chr12_+_12510045 0.16 ENST00000314565.4
loss of heterozygosity, 12, chromosomal region 1
chr16_+_57662138 0.16 ENST00000562414.1
ENST00000561969.1
ENST00000562631.1
ENST00000563445.1
ENST00000565338.1
ENST00000567702.1
G protein-coupled receptor 56
chr22_-_45608324 0.16 ENST00000496226.1
ENST00000251993.7
KIAA0930
chr1_+_229440129 0.16 ENST00000366688.3
S-phase response (cyclin related)
chr11_-_9781068 0.16 ENST00000500698.1
RP11-540A21.2
chr7_-_100026280 0.16 ENST00000360951.4
ENST00000398027.2
ENST00000324725.6
ENST00000472716.1
zinc finger, CW type with PWWP domain 1
chr12_-_58026426 0.16 ENST00000418555.2
beta-1,4-N-acetyl-galactosaminyl transferase 1
chr20_-_43280325 0.16 ENST00000537820.1
adenosine deaminase
chr7_+_42971799 0.16 ENST00000223324.2
mitochondrial ribosomal protein L32
chr12_+_12509990 0.16 ENST00000542728.1
loss of heterozygosity, 12, chromosomal region 1
chr11_-_65430251 0.15 ENST00000534283.1
ENST00000527749.1
ENST00000533187.1
ENST00000525693.1
ENST00000534558.1
ENST00000532879.1
ENST00000532999.1
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr20_-_634000 0.15 ENST00000381962.3
sulfiredoxin 1
chr10_-_73611046 0.15 ENST00000394934.1
ENST00000394936.3
prosaposin
chr17_-_39623681 0.15 ENST00000225899.3
keratin 32
chr19_+_38880695 0.15 ENST00000587947.1
ENST00000338502.4
sprouty-related, EVH1 domain containing 3
chr12_-_51611477 0.15 ENST00000389243.4
POU class 6 homeobox 1
chr3_+_197687071 0.15 ENST00000482695.1
ENST00000330198.4
ENST00000419117.1
ENST00000420910.2
ENST00000332636.5
leishmanolysin-like (metallopeptidase M8 family)
chr6_-_33285505 0.15 ENST00000431845.2
zinc finger and BTB domain containing 22
chr7_-_115670792 0.15 ENST00000265440.7
ENST00000393485.1
transcription factor EC
chr17_-_37886752 0.15 ENST00000577810.1
migration and invasion enhancer 1
chr22_-_19466732 0.14 ENST00000263202.10
ENST00000360834.4
ubiquitin fusion degradation 1 like (yeast)
chr11_+_125365110 0.14 ENST00000527818.1
AP000708.1
chr17_+_16284104 0.14 ENST00000577958.1
ENST00000302182.3
ENST00000577640.1
ubiquitin B
chr19_+_18496957 0.14 ENST00000252809.3
growth differentiation factor 15
chr11_-_2906979 0.14 ENST00000380725.1
ENST00000313407.6
ENST00000430149.2
ENST00000440480.2
ENST00000414822.3
cyclin-dependent kinase inhibitor 1C (p57, Kip2)
chr11_+_62649158 0.14 ENST00000539891.1
ENST00000536981.1
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr12_-_57030115 0.14 ENST00000379441.3
ENST00000179765.5
ENST00000551812.1
bromodomain adjacent to zinc finger domain, 2A
chr22_-_39268192 0.14 ENST00000216083.6
chromobox homolog 6

Network of associatons between targets according to the STRING database.

First level regulatory network of BACH1_NFE2_NFE2L2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0061433 cellular response to caloric restriction(GO:0061433) negative regulation of oligodendrocyte progenitor proliferation(GO:0070446)
0.1 0.4 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.1 1.5 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.1 0.5 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.1 0.4 GO:0046103 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
0.1 0.6 GO:0070541 response to platinum ion(GO:0070541)
0.1 1.1 GO:0034036 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.1 0.3 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.1 0.5 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.1 0.3 GO:0090677 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.1 1.3 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 0.2 GO:0060345 spleen trabecula formation(GO:0060345) iron cation export(GO:1903414) ferrous iron export(GO:1903988)
0.1 1.6 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 1.0 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 0.1 GO:1902534 single-organism membrane invagination(GO:1902534)
0.1 0.2 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.1 0.2 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.1 0.2 GO:0090410 malonate catabolic process(GO:0090410)
0.1 0.2 GO:0072387 flavin adenine dinucleotide metabolic process(GO:0072387)
0.1 0.2 GO:0006624 vacuolar protein processing(GO:0006624)
0.1 0.3 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.0 0.8 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.4 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.0 0.2 GO:0030222 eosinophil differentiation(GO:0030222)
0.0 0.5 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.0 0.2 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.0 0.2 GO:0042377 menaquinone catabolic process(GO:0042361) vitamin K catabolic process(GO:0042377)
0.0 0.5 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.0 0.5 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.2 GO:1904383 response to sodium phosphate(GO:1904383)
0.0 0.2 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.0 0.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.5 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.6 GO:0015886 heme transport(GO:0015886)
0.0 0.2 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.3 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.0 0.1 GO:0016488 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488)
0.0 0.3 GO:0070560 protein secretion by platelet(GO:0070560)
0.0 0.1 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.0 0.3 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.1 GO:0046521 sphingoid catabolic process(GO:0046521)
0.0 0.5 GO:0051546 keratinocyte migration(GO:0051546)
0.0 0.5 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.4 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.2 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.0 0.2 GO:2001205 TNFSF11-mediated signaling pathway(GO:0071847) negative regulation of osteoclast development(GO:2001205)
0.0 0.3 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0 0.2 GO:0040031 snRNA modification(GO:0040031)
0.0 0.1 GO:1904977 lymphatic endothelial cell migration(GO:1904977)
0.0 0.1 GO:0006238 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.0 0.8 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.0 0.1 GO:1904387 cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.0 0.5 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.1 GO:0060356 leucine import(GO:0060356)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.1 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.0 0.1 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.1 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 0.1 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499)
0.0 0.4 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107) peptidyl-threonine modification(GO:0018210)
0.0 0.2 GO:0035897 proteolysis in other organism(GO:0035897)
0.0 0.0 GO:0034136 negative regulation of toll-like receptor 2 signaling pathway(GO:0034136)
0.0 0.4 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.1 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.1 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.0 GO:0060981 cell migration involved in coronary angiogenesis(GO:0060981)
0.0 0.3 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.6 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.0 0.3 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.3 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.2 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 0.0 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.0 0.1 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.0 0.5 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.9 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.3 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.9 GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423)
0.0 0.0 GO:1904717 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.0 0.3 GO:0006265 DNA topological change(GO:0006265)
0.0 0.1 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.2 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.1 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.0 0.0 GO:0060167 regulation of adenosine receptor signaling pathway(GO:0060167)
0.0 0.1 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.1 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.2 GO:0003417 growth plate cartilage development(GO:0003417)
0.0 0.2 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0044753 amphisome(GO:0044753)
0.2 0.5 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.2 0.5 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.1 0.3 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.1 0.3 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.1 0.6 GO:0032437 cuticular plate(GO:0032437)
0.1 0.3 GO:0031673 H zone(GO:0031673)
0.1 0.6 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.1 GO:0034515 proteasome storage granule(GO:0034515)
0.0 0.6 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.9 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 1.6 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.1 GO:0097444 spine apparatus(GO:0097444)
0.0 0.3 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.1 GO:0009986 cell surface(GO:0009986)
0.0 0.2 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 0.5 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 1.8 GO:0031430 M band(GO:0031430)
0.0 0.3 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.1 GO:0045160 myosin I complex(GO:0045160)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.2 GO:0097452 GAIT complex(GO:0097452)
0.0 0.1 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.0 0.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.3 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.5 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0097513 myosin II filament(GO:0097513)
0.0 0.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 1.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.2 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.1 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.6 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.2 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.3 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.3 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.0 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.2 0.7 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.2 0.6 GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.2 0.6 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.2 0.9 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.2 0.6 GO:0004325 ferrochelatase activity(GO:0004325)
0.1 0.5 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.1 0.4 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.1 1.3 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.4 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.1 0.3 GO:0019862 IgA binding(GO:0019862)
0.1 1.6 GO:0030957 Tat protein binding(GO:0030957)
0.1 0.5 GO:0070026 nitric oxide binding(GO:0070026)
0.1 0.2 GO:0097689 iron channel activity(GO:0097689)
0.1 1.1 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 0.3 GO:0003947 (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity(GO:0003947)
0.1 0.2 GO:0003955 NAD(P)H dehydrogenase (quinone) activity(GO:0003955)
0.1 0.2 GO:0090409 malonyl-CoA synthetase activity(GO:0090409)
0.1 0.5 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.1 0.2 GO:0031783 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.0 0.2 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.5 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.9 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.2 GO:0098626 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.0 0.3 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.2 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.0 0.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.1 GO:0045550 geranylgeranyl reductase activity(GO:0045550)
0.0 0.3 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.5 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.3 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.2 GO:0045174 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.0 0.4 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.5 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.0 0.2 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0 0.8 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.3 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.0 0.1 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.0 0.1 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.1 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.0 0.1 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.0 0.5 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.6 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.4 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.1 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.1 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.0 0.1 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.1 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.2 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.0 GO:0005019 platelet-derived growth factor beta-receptor activity(GO:0005019)
0.0 0.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.5 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.0 0.2 GO:0017166 vinculin binding(GO:0017166)
0.0 2.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.3 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.1 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.9 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.9 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 2.0 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.2 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.5 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.3 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 1.1 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.1 1.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 1.1 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.9 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 1.1 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.5 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 1.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.5 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.2 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.7 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.3 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.2 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.5 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.8 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.6 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport