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avrg: A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for KLF7

Z-value: 0.24

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Transcription factors associated with KLF7

Gene Symbol Gene ID Gene Info
ENSG00000118263.10 KLF7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
KLF7hg19_v2_chr2_-_208030886_2080309170.623.8e-01Click!

Activity profile of KLF7 motif

Sorted Z-values of KLF7 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF7

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr19_-_39390212 0.20 ENST00000437828.1
SIRT2
sirtuin 2
chr12_-_49582593 0.18 ENST00000295766.5
TUBA1A
tubulin, alpha 1a
chr1_-_21948906 0.17 ENST00000374761.2
ENST00000599760.1
RAP1GAP
RAP1 GTPase activating protein
chr12_-_49581152 0.16 ENST00000550811.1
TUBA1A
tubulin, alpha 1a
chr1_-_19229014 0.15 ENST00000538839.1
ENST00000290597.5
ALDH4A1
aldehyde dehydrogenase 4 family, member A1
chr12_-_49582837 0.14 ENST00000547939.1
ENST00000546918.1
ENST00000552924.1
TUBA1A
tubulin, alpha 1a
chr1_-_19229248 0.13 ENST00000375341.3
ALDH4A1
aldehyde dehydrogenase 4 family, member A1
chr2_-_74710078 0.10 ENST00000290418.4
CCDC142
coiled-coil domain containing 142
chr9_-_35812140 0.09 ENST00000497810.1
ENST00000396638.2
ENST00000484764.1
SPAG8
sperm associated antigen 8
chr15_+_96873921 0.09 ENST00000394166.3
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr17_+_18218587 0.09 ENST00000406438.3
SMCR8
Smith-Magenis syndrome chromosome region, candidate 8
chr1_+_28157273 0.08 ENST00000311772.5
ENST00000236412.7
ENST00000373931.4
PPP1R8
protein phosphatase 1, regulatory subunit 8
chr19_-_39390440 0.08 ENST00000249396.7
ENST00000414941.1
ENST00000392081.2
SIRT2
sirtuin 2
chr3_+_186353756 0.07 ENST00000431018.1
ENST00000450521.1
ENST00000539949.1
FETUB
fetuin B
chr18_+_72166564 0.06 ENST00000583216.1
ENST00000581912.1
ENST00000582589.1
CNDP2
CNDP dipeptidase 2 (metallopeptidase M20 family)
chr19_-_39390350 0.06 ENST00000447739.1
ENST00000358931.5
ENST00000407552.1
SIRT2
sirtuin 2
chr3_+_105085734 0.06 ENST00000306107.5
ALCAM
activated leukocyte cell adhesion molecule
chr9_+_130565568 0.06 ENST00000423577.1
FPGS
folylpolyglutamate synthase
chr17_-_18218237 0.06 ENST00000542570.1
TOP3A
topoisomerase (DNA) III alpha
chr6_+_33239787 0.05 ENST00000439602.2
ENST00000474973.1
RPS18
ribosomal protein S18
chr6_-_109703634 0.05 ENST00000324953.5
ENST00000310786.4
ENST00000275080.7
ENST00000413644.2
CD164
CD164 molecule, sialomucin
chr1_+_87380299 0.05 ENST00000370551.4
ENST00000370550.5
HS2ST1
heparan sulfate 2-O-sulfotransferase 1
chr1_-_19229218 0.04 ENST00000432718.1
ALDH4A1
aldehyde dehydrogenase 4 family, member A1
chr6_+_30585486 0.04 ENST00000259873.4
ENST00000506373.2
MRPS18B
mitochondrial ribosomal protein S18B
chr14_+_38660185 0.04 ENST00000555655.1
CTD-2142D14.1
CTD-2142D14.1
chr17_-_18218270 0.04 ENST00000321105.5
TOP3A
topoisomerase (DNA) III alpha
chrX_+_92929192 0.04 ENST00000332647.4
FAM133A
family with sequence similarity 133, member A
chr3_-_33138624 0.03 ENST00000445488.2
ENST00000307377.8
ENST00000440656.1
ENST00000436768.1
ENST00000307363.5
GLB1
galactosidase, beta 1
chr2_+_97779233 0.03 ENST00000461153.2
ENST00000420699.2
ANKRD36
ankyrin repeat domain 36
chr19_+_39390587 0.03 ENST00000572515.1
ENST00000392079.3
ENST00000575359.1
ENST00000313582.5
NFKBIB
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr19_+_7694623 0.03 ENST00000594797.1
ENST00000456958.3
ENST00000601406.1
PET100
PET100 homolog (S. cerevisiae)
chr5_+_176560007 0.03 ENST00000510954.1
ENST00000354179.4
NSD1
nuclear receptor binding SET domain protein 1
chr2_+_74710194 0.03 ENST00000410003.1
ENST00000442235.2
ENST00000233623.5
TTC31
tetratricopeptide repeat domain 31
chr17_+_19282064 0.03 ENST00000603493.1
MAPK7
mitogen-activated protein kinase 7
chr9_+_130565487 0.03 ENST00000373225.3
ENST00000431857.1
FPGS
folylpolyglutamate synthase
chr8_-_17104356 0.03 ENST00000361272.4
ENST00000523917.1
CNOT7
CCR4-NOT transcription complex, subunit 7
chr6_+_43603552 0.02 ENST00000372171.4
MAD2L1BP
MAD2L1 binding protein
chrX_+_102631844 0.02 ENST00000372634.1
ENST00000299872.7
NGFRAP1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr6_-_109703600 0.02 ENST00000512821.1
CD164
CD164 molecule, sialomucin
chr5_+_141348598 0.02 ENST00000394520.2
ENST00000347642.3
RNF14
ring finger protein 14
chr20_-_2821756 0.02 ENST00000356872.3
ENST00000439542.1
PCED1A
PC-esterase domain containing 1A
chr1_-_161102367 0.02 ENST00000464113.1
DEDD
death effector domain containing
chr8_+_72587535 0.01 ENST00000519840.1
ENST00000521131.1
RP11-1144P22.1
RP11-1144P22.1
chr9_+_130565147 0.01 ENST00000373247.2
ENST00000373245.1
ENST00000393706.2
ENST00000373228.1
FPGS
folylpolyglutamate synthase
chr6_+_31865552 0.00 ENST00000469372.1
ENST00000497706.1
C2
complement component 2
chr20_+_2821366 0.00 ENST00000453689.1
ENST00000417508.1
VPS16
vacuolar protein sorting 16 homolog (S. cerevisiae)
chr22_-_30987849 0.00 ENST00000402284.3
ENST00000354694.7
PES1
pescadillo ribosomal biogenesis factor 1
chr17_+_19281787 0.00 ENST00000482850.1
MAPK7
mitogen-activated protein kinase 7

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0061433 cellular response to caloric restriction(GO:0061433) negative regulation of oligodendrocyte progenitor proliferation(GO:0070446)
0.1 0.2 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.1 0.3 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.0 0.1 GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process(GO:0046901)
0.0 0.1 GO:0009956 radial pattern formation(GO:0009956)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0072687 meiotic spindle(GO:0072687)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.1 0.3 GO:0003842 1-pyrroline-5-carboxylate dehydrogenase activity(GO:0003842)
0.0 0.1 GO:0004326 tetrahydrofolylpolyglutamate synthase activity(GO:0004326) dihydrofolate synthase activity(GO:0008841)
0.0 0.1 GO:0102008 cytosolic dipeptidase activity(GO:0102008)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway