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avrg: A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for TP73

Z-value: 0.92

Motif logo

Transcription factors associated with TP73

Gene Symbol Gene ID Gene Info
ENSG00000078900.10 TP73

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TP73hg19_v2_chr1_+_3569129_35691500.653.5e-01Click!

Activity profile of TP73 motif

Sorted Z-values of TP73 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TP73

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr20_-_62203808 1.31 ENST00000467148.1
HELZ2
helicase with zinc finger 2, transcriptional coactivator
chr20_+_35504522 0.89 ENST00000602922.1
ENST00000217320.3
TLDC2
TBC/LysM-associated domain containing 2
chr17_+_73750699 0.69 ENST00000584939.1
ITGB4
integrin, beta 4
chr3_+_136676707 0.57 ENST00000329582.4
IL20RB
interleukin 20 receptor beta
chr20_+_48807351 0.53 ENST00000303004.3
CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr11_+_65154070 0.52 ENST00000317568.5
ENST00000531296.1
ENST00000533782.1
ENST00000355991.5
ENST00000416776.2
ENST00000526201.1
FRMD8
FERM domain containing 8
chr15_+_74466744 0.49 ENST00000560862.1
ENST00000395118.1
ISLR
immunoglobulin superfamily containing leucine-rich repeat
chr3_+_136676851 0.46 ENST00000309741.5
IL20RB
interleukin 20 receptor beta
chr16_+_8891670 0.43 ENST00000268261.4
ENST00000539622.1
ENST00000569958.1
ENST00000537352.1
PMM2
phosphomannomutase 2
chr10_-_99185798 0.38 ENST00000439965.2
AL355490.1
LOC644215 protein; Uncharacterized protein
chr10_-_47173994 0.36 ENST00000414655.2
ENST00000545298.1
ENST00000359178.4
ENST00000358140.4
ENST00000503031.1
ANXA8L1
LINC00842
annexin A8-like 1
long intergenic non-protein coding RNA 842
chr22_-_20255212 0.35 ENST00000416372.1
RTN4R
reticulon 4 receptor
chr15_+_57891609 0.32 ENST00000569089.1
MYZAP
myocardial zonula adherens protein
chr17_-_42452063 0.32 ENST00000588098.1
ITGA2B
integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
chr10_+_47746929 0.32 ENST00000340243.6
ENST00000374277.5
ENST00000449464.2
ENST00000538825.1
ENST00000335083.5
ANXA8L2
AL603965.1
annexin A8-like 2
Protein LOC100996760
chr22_+_39966758 0.31 ENST00000407673.1
ENST00000401624.1
ENST00000404898.1
ENST00000402142.3
ENST00000336649.4
ENST00000400164.3
CACNA1I
calcium channel, voltage-dependent, T type, alpha 1I subunit
chr2_-_26864228 0.29 ENST00000288861.4
CIB4
calcium and integrin binding family member 4
chr7_-_100493482 0.29 ENST00000411582.1
ENST00000419336.2
ENST00000241069.5
ENST00000302913.4
ACHE
acetylcholinesterase (Yt blood group)
chr2_-_230135937 0.29 ENST00000392054.3
ENST00000409462.1
ENST00000392055.3
PID1
phosphotyrosine interaction domain containing 1
chr8_+_145065521 0.23 ENST00000534791.1
GRINA
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr6_-_33256664 0.22 ENST00000444176.1
WDR46
WD repeat domain 46
chr5_+_125758813 0.22 ENST00000285689.3
ENST00000515200.1
GRAMD3
GRAM domain containing 3
chr17_-_40835076 0.22 ENST00000591765.1
CCR10
chemokine (C-C motif) receptor 10
chr5_+_125758865 0.21 ENST00000542322.1
ENST00000544396.1
GRAMD3
GRAM domain containing 3
chr15_-_74043816 0.21 ENST00000379822.4
C15orf59
chromosome 15 open reading frame 59
chr15_+_75498739 0.21 ENST00000565074.1
C15orf39
chromosome 15 open reading frame 39
chr10_-_105238997 0.20 ENST00000369783.4
CALHM3
calcium homeostasis modulator 3
chrX_-_80377162 0.20 ENST00000430960.1
ENST00000447319.1
HMGN5
high mobility group nucleosome binding domain 5
chr7_-_100171270 0.20 ENST00000538735.1
SAP25
Sin3A-associated protein, 25kDa
chr12_-_82752159 0.20 ENST00000552377.1
CCDC59
coiled-coil domain containing 59
chr17_+_43318434 0.20 ENST00000587489.1
FMNL1
formin-like 1
chr1_-_78444776 0.19 ENST00000370767.1
ENST00000421641.1
FUBP1
far upstream element (FUSE) binding protein 1
chr8_+_145065705 0.18 ENST00000533044.1
GRINA
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr1_-_78444738 0.18 ENST00000436586.2
ENST00000370768.2
FUBP1
far upstream element (FUSE) binding protein 1
chr9_+_6758109 0.18 ENST00000536108.1
KDM4C
lysine (K)-specific demethylase 4C
chr3_+_48481658 0.18 ENST00000438607.2
TMA7
translation machinery associated 7 homolog (S. cerevisiae)
chr10_-_97200772 0.18 ENST00000371241.1
ENST00000354106.3
ENST00000371239.1
ENST00000361941.3
ENST00000277982.5
ENST00000371245.3
SORBS1
sorbin and SH3 domain containing 1
chr14_-_75078725 0.18 ENST00000556690.1
LTBP2
latent transforming growth factor beta binding protein 2
chr15_+_75498355 0.18 ENST00000567617.1
C15orf39
chromosome 15 open reading frame 39
chr15_+_41136369 0.17 ENST00000563656.1
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr15_+_41136263 0.17 ENST00000568823.1
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr14_+_103566665 0.17 ENST00000559116.1
EXOC3L4
exocyst complex component 3-like 4
chr9_-_128003606 0.17 ENST00000324460.6
HSPA5
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
chr14_+_105935396 0.16 ENST00000494981.1
MTA1
metastasis associated 1
chr19_+_45254529 0.15 ENST00000444487.1
BCL3
B-cell CLL/lymphoma 3
chr8_+_54764346 0.15 ENST00000297313.3
ENST00000344277.6
RGS20
regulator of G-protein signaling 20
chr2_+_220283091 0.15 ENST00000373960.3
DES
desmin
chr16_+_67197288 0.15 ENST00000264009.8
ENST00000421453.1
HSF4
heat shock transcription factor 4
chr5_+_43120985 0.15 ENST00000515326.1
ZNF131
zinc finger protein 131
chr17_+_37356528 0.14 ENST00000225430.4
RPL19
ribosomal protein L19
chr9_+_6758024 0.14 ENST00000442236.2
KDM4C
lysine (K)-specific demethylase 4C
chr9_+_6757634 0.13 ENST00000543771.1
ENST00000401787.3
ENST00000381306.3
ENST00000381309.3
KDM4C
lysine (K)-specific demethylase 4C
chr16_+_84178874 0.13 ENST00000378553.5
DNAAF1
dynein, axonemal, assembly factor 1
chr1_-_68698222 0.13 ENST00000370976.3
ENST00000354777.2
ENST00000262348.4
ENST00000540432.1
WLS
wntless Wnt ligand secretion mediator
chr15_+_64680003 0.13 ENST00000261884.3
TRIP4
thyroid hormone receptor interactor 4
chr16_-_84178728 0.13 ENST00000562224.1
ENST00000434463.3
ENST00000564998.1
ENST00000219439.4
HSDL1
hydroxysteroid dehydrogenase like 1
chr3_+_100120441 0.12 ENST00000489752.1
LNP1
leukemia NUP98 fusion partner 1
chr17_+_72427477 0.11 ENST00000342648.5
ENST00000481232.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr2_-_232328867 0.11 ENST00000453992.1
ENST00000417652.1
ENST00000454824.1
NCL
nucleolin
chr19_+_49622646 0.11 ENST00000334186.4
PPFIA3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr14_-_25519317 0.10 ENST00000323944.5
STXBP6
syntaxin binding protein 6 (amisyn)
chr20_-_52790512 0.10 ENST00000216862.3
CYP24A1
cytochrome P450, family 24, subfamily A, polypeptide 1
chr6_+_155538093 0.10 ENST00000462408.2
TIAM2
T-cell lymphoma invasion and metastasis 2
chr7_-_2883928 0.10 ENST00000275364.3
GNA12
guanine nucleotide binding protein (G protein) alpha 12
chr8_-_70745575 0.09 ENST00000524945.1
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr6_-_112194484 0.09 ENST00000518295.1
ENST00000484067.2
ENST00000229470.5
ENST00000356013.2
ENST00000368678.4
ENST00000523238.1
ENST00000354650.3
FYN
FYN oncogene related to SRC, FGR, YES
chr8_-_145016692 0.09 ENST00000357649.2
PLEC
plectin
chr7_-_27213893 0.09 ENST00000283921.4
HOXA10
homeobox A10
chr5_+_125759140 0.09 ENST00000543198.1
GRAMD3
GRAM domain containing 3
chr16_+_75032901 0.09 ENST00000335325.4
ENST00000320619.6
ZNRF1
zinc and ring finger 1, E3 ubiquitin protein ligase
chr18_+_77623668 0.09 ENST00000316249.3
KCNG2
potassium voltage-gated channel, subfamily G, member 2
chr14_-_25519095 0.09 ENST00000419632.2
ENST00000358326.2
ENST00000396700.1
ENST00000548724.1
STXBP6
syntaxin binding protein 6 (amisyn)
chr20_-_49253425 0.09 ENST00000045083.2
FAM65C
family with sequence similarity 65, member C
chr4_+_6717842 0.08 ENST00000320776.3
BLOC1S4
biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino
chr2_-_158485387 0.08 ENST00000243349.8
ACVR1C
activin A receptor, type IC
chr16_+_84178850 0.08 ENST00000334315.5
DNAAF1
dynein, axonemal, assembly factor 1
chr1_+_47137544 0.08 ENST00000564373.1
TEX38
testis expressed 38
chr1_+_156785425 0.07 ENST00000392302.2
NTRK1
neurotrophic tyrosine kinase, receptor, type 1
chr17_-_47492236 0.07 ENST00000434917.2
ENST00000300408.3
ENST00000511832.1
ENST00000419140.2
PHB
prohibitin
chr2_-_73511559 0.07 ENST00000521871.1
FBXO41
F-box protein 41
chr20_-_52790055 0.07 ENST00000395955.3
CYP24A1
cytochrome P450, family 24, subfamily A, polypeptide 1
chr12_-_82752565 0.07 ENST00000256151.7
CCDC59
coiled-coil domain containing 59
chr1_+_162467595 0.07 ENST00000538489.1
ENST00000489294.1
UHMK1
U2AF homology motif (UHM) kinase 1
chr17_-_79818354 0.07 ENST00000576541.1
ENST00000576380.1
ENST00000571617.1
ENST00000576052.1
ENST00000576390.1
ENST00000573778.2
ENST00000439918.2
ENST00000574914.1
ENST00000331483.4
P4HB
prolyl 4-hydroxylase, beta polypeptide
chr11_-_17035943 0.06 ENST00000355661.3
ENST00000532079.1
ENST00000448080.2
ENST00000531066.1
PLEKHA7
pleckstrin homology domain containing, family A member 7
chr1_-_52344471 0.06 ENST00000352171.7
ENST00000354831.7
NRD1
nardilysin (N-arginine dibasic convertase)
chr19_-_35981358 0.06 ENST00000484218.2
ENST00000338897.3
KRTDAP
keratinocyte differentiation-associated protein
chr15_+_41136216 0.06 ENST00000562057.1
ENST00000344051.4
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr11_-_31833719 0.06 ENST00000524853.1
PAX6
paired box 6
chr18_-_4455260 0.05 ENST00000581527.1
DLGAP1
discs, large (Drosophila) homolog-associated protein 1
chr12_+_96196875 0.05 ENST00000553095.1
RP11-536G4.1
Uncharacterized protein
chr2_-_27357479 0.05 ENST00000406567.3
ENST00000260643.2
PREB
prolactin regulatory element binding
chr16_+_222846 0.05 ENST00000251595.6
ENST00000397806.1
HBA2
hemoglobin, alpha 2
chr19_-_39226045 0.05 ENST00000597987.1
ENST00000595177.1
CAPN12
calpain 12
chr1_+_47137445 0.05 ENST00000569393.1
ENST00000334122.4
ENST00000415500.1
TEX38
testis expressed 38
chr17_+_37356586 0.05 ENST00000579260.1
ENST00000582193.1
RPL19
ribosomal protein L19
chr17_-_2615031 0.05 ENST00000576885.1
ENST00000574426.2
CLUH
clustered mitochondria (cluA/CLU1) homolog
chr7_-_128045984 0.04 ENST00000470772.1
ENST00000480861.1
ENST00000496200.1
IMPDH1
IMP (inosine 5'-monophosphate) dehydrogenase 1
chr11_+_236959 0.04 ENST00000431206.2
ENST00000528906.1
PSMD13
proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
chr17_+_37356555 0.04 ENST00000579374.1
RPL19
ribosomal protein L19
chr19_+_19627026 0.04 ENST00000608404.1
ENST00000555938.1
ENST00000503283.1
ENST00000512771.3
ENST00000428459.2
YJEFN3
CTC-260F20.3
NDUFA13
YjeF N-terminal domain containing 3
Uncharacterized protein
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
chr17_-_2614927 0.04 ENST00000435359.1
CLUH
clustered mitochondria (cluA/CLU1) homolog
chrX_-_138724994 0.04 ENST00000536274.1
MCF2
MCF.2 cell line derived transforming sequence
chr9_+_87285257 0.04 ENST00000323115.4
NTRK2
neurotrophic tyrosine kinase, receptor, type 2
chr7_-_100493744 0.04 ENST00000428317.1
ENST00000441605.1
ACHE
acetylcholinesterase (Yt blood group)
chr9_-_130517309 0.04 ENST00000414380.1
SH2D3C
SH2 domain containing 3C
chr16_+_67195592 0.04 ENST00000519378.1
FBXL8
F-box and leucine-rich repeat protein 8
chr17_-_47492164 0.04 ENST00000512041.2
ENST00000446735.1
ENST00000504124.1
PHB
prohibitin
chrX_-_80377118 0.03 ENST00000373250.3
HMGN5
high mobility group nucleosome binding domain 5
chrX_-_138724677 0.03 ENST00000370573.4
ENST00000338585.6
ENST00000370576.4
MCF2
MCF.2 cell line derived transforming sequence
chr1_-_236228403 0.03 ENST00000366595.3
NID1
nidogen 1
chr1_-_68698197 0.03 ENST00000370973.2
ENST00000370971.1
WLS
wntless Wnt ligand secretion mediator
chr9_+_133223932 0.03 ENST00000420499.2
HMCN2
hemicentin 2
chr2_+_95940220 0.03 ENST00000542147.1
PROM2
prominin 2
chr16_-_14724057 0.03 ENST00000539279.1
ENST00000420015.2
ENST00000437198.2
PARN
poly(A)-specific ribonuclease
chr15_+_41136586 0.03 ENST00000431806.1
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr16_-_1146244 0.03 ENST00000328449.5
C1QTNF8
C1q and tumor necrosis factor related protein 8
chr17_+_78388959 0.02 ENST00000518137.1
ENST00000520367.1
ENST00000523999.1
ENST00000323854.5
ENST00000522751.1
ENDOV
endonuclease V
chr2_-_26205550 0.02 ENST00000405914.1
KIF3C
kinesin family member 3C
chr18_-_53253000 0.02 ENST00000566514.1
TCF4
transcription factor 4
chr9_+_36169380 0.02 ENST00000335119.2
CCIN
calicin
chr1_+_110082487 0.02 ENST00000527748.1
GPR61
G protein-coupled receptor 61
chr9_-_132383055 0.02 ENST00000372478.4
C9orf50
chromosome 9 open reading frame 50
chr1_-_236228417 0.01 ENST00000264187.6
NID1
nidogen 1
chr6_-_46703069 0.01 ENST00000538237.1
ENST00000274793.7
PLA2G7
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr6_+_31515337 0.01 ENST00000376148.4
ENST00000376145.4
NFKBIL1
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
chrX_+_9880590 0.01 ENST00000452575.1
SHROOM2
shroom family member 2
chr12_+_113495492 0.01 ENST00000257600.3
DTX1
deltex homolog 1 (Drosophila)
chr11_+_66234216 0.01 ENST00000349459.6
ENST00000320740.7
ENST00000524466.1
ENST00000526296.1
PELI3
pellino E3 ubiquitin protein ligase family member 3
chr19_-_19626838 0.01 ENST00000360913.3
TSSK6
testis-specific serine kinase 6
chr18_-_53253323 0.01 ENST00000540999.1
ENST00000563888.2
TCF4
transcription factor 4
chr10_-_105212059 0.01 ENST00000260743.5
CALHM2
calcium homeostasis modulator 2
chr11_-_65686496 0.00 ENST00000449692.3
C11orf68
chromosome 11 open reading frame 68
chr1_-_214724566 0.00 ENST00000366956.5
PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr9_+_138391805 0.00 ENST00000371785.1
MRPS2
mitochondrial ribosomal protein S2
chr17_-_39023462 0.00 ENST00000251643.4
KRT12
keratin 12

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.1 0.3 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.1 0.4 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.1 0.3 GO:0070346 positive regulation of fat cell proliferation(GO:0070346)
0.1 0.2 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.0 0.7 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.2 GO:0042369 vitamin D catabolic process(GO:0042369)
0.0 0.5 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.7 GO:0035878 nail development(GO:0035878)
0.0 0.2 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.0 0.2 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499)
0.0 0.2 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.1 GO:0097360 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.0 0.4 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 0.1 GO:2000259 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.0 0.4 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.3 GO:0051601 exocyst localization(GO:0051601)
0.0 0.2 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.0 0.4 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.2 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.8 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.3 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.1 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 0.5 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.1 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 0.4 GO:0038131 neuregulin receptor activity(GO:0038131)
0.1 0.3 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 0.3 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.1 0.3 GO:0070051 fibrinogen binding(GO:0070051)
0.1 0.2 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.7 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.2 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.0 0.4 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.5 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.5 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.0 1.3 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.0 GO:0052857 NADHX epimerase activity(GO:0052856) NADPHX epimerase activity(GO:0052857)
0.0 0.1 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.2 GO:0031852 mu-type opioid receptor binding(GO:0031852)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.2 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.3 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC