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avrg: A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for HOXA2_HOXB1

Z-value: 0.09

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Transcription factors associated with HOXA2_HOXB1

Gene Symbol Gene ID Gene Info
ENSG00000105996.5 HOXA2
ENSG00000120094.6 HOXB1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXA2hg19_v2_chr7_-_27142290_27142430-0.851.5e-01Click!

Activity profile of HOXA2_HOXB1 motif

Sorted Z-values of HOXA2_HOXB1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXA2_HOXB1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr3_+_159481988 0.25 ENST00000472451.1
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr7_-_27170352 0.19 ENST00000428284.2
ENST00000360046.5
HOXA4
homeobox A4
chr21_-_43430440 0.15 ENST00000398505.3
ENST00000310826.5
ENST00000449949.1
ENST00000398499.1
ENST00000398497.2
ENST00000398511.3
ZBTB21
zinc finger and BTB domain containing 21
chrX_+_41583408 0.10 ENST00000302548.4
GPR82
G protein-coupled receptor 82
chr6_+_32006042 0.10 ENST00000418967.2
CYP21A2
cytochrome P450, family 21, subfamily A, polypeptide 2
chr12_+_21679220 0.08 ENST00000256969.2
C12orf39
chromosome 12 open reading frame 39
chr1_-_217804377 0.08 ENST00000366935.3
ENST00000366934.3
GPATCH2
G patch domain containing 2
chrX_-_10645773 0.08 ENST00000453318.2
MID1
midline 1 (Opitz/BBB syndrome)
chr8_+_23386557 0.08 ENST00000523930.1
SLC25A37
solute carrier family 25 (mitochondrial iron transporter), member 37
chr3_+_150264555 0.07 ENST00000406576.3
ENST00000482093.1
ENST00000273435.5
EIF2A
eukaryotic translation initiation factor 2A, 65kDa
chr3_+_150264458 0.07 ENST00000487799.1
ENST00000460851.1
EIF2A
eukaryotic translation initiation factor 2A, 65kDa
chr16_+_85936295 0.07 ENST00000563180.1
ENST00000564617.1
ENST00000564803.1
IRF8
interferon regulatory factor 8
chr5_+_162864575 0.07 ENST00000512163.1
ENST00000393929.1
ENST00000340828.2
ENST00000511683.2
ENST00000510097.1
ENST00000511490.2
ENST00000510664.1
CCNG1
cyclin G1
chr8_+_143530791 0.07 ENST00000517894.1
BAI1
brain-specific angiogenesis inhibitor 1
chr2_+_12857043 0.06 ENST00000381465.2
TRIB2
tribbles pseudokinase 2
chr17_-_57229155 0.06 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr6_-_159065741 0.06 ENST00000367085.3
ENST00000367089.3
DYNLT1
dynein, light chain, Tctex-type 1
chrX_+_95939638 0.06 ENST00000373061.3
ENST00000373054.4
ENST00000355827.4
DIAPH2
diaphanous-related formin 2
chr12_+_10658489 0.06 ENST00000538173.1
EIF2S3L
Putative eukaryotic translation initiation factor 2 subunit 3-like protein
chr1_-_92351666 0.06 ENST00000465892.2
ENST00000417833.2
TGFBR3
transforming growth factor, beta receptor III
chr10_+_24755416 0.05 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217
KIAA1217
chr2_+_135011731 0.05 ENST00000281923.2
MGAT5
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chr2_-_200322723 0.05 ENST00000417098.1
SATB2
SATB homeobox 2
chr6_-_64029879 0.05 ENST00000370658.5
ENST00000485906.2
ENST00000370657.4
LGSN
lengsin, lens protein with glutamine synthetase domain
chr7_-_100881041 0.05 ENST00000412417.1
ENST00000414035.1
CLDN15
claudin 15
chr5_+_98109322 0.05 ENST00000513185.1
RGMB
repulsive guidance molecule family member b
chr10_+_102505468 0.05 ENST00000361791.3
ENST00000355243.3
ENST00000428433.1
ENST00000370296.2
PAX2
paired box 2
chr10_+_89264625 0.05 ENST00000371996.4
ENST00000371994.4
MINPP1
multiple inositol-polyphosphate phosphatase 1
chr11_+_57365150 0.05 ENST00000457869.1
ENST00000340687.6
ENST00000378323.4
ENST00000378324.2
ENST00000403558.1
SERPING1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr5_+_145826867 0.05 ENST00000296702.5
ENST00000394421.2
TCERG1
transcription elongation regulator 1
chr7_-_143956815 0.04 ENST00000493325.1
OR2A7
olfactory receptor, family 2, subfamily A, member 7
chr8_+_23386305 0.04 ENST00000519973.1
SLC25A37
solute carrier family 25 (mitochondrial iron transporter), member 37
chr2_-_200323414 0.04 ENST00000443023.1
SATB2
SATB homeobox 2
chr9_-_15250114 0.04 ENST00000507993.1
TTC39B
tetratricopeptide repeat domain 39B
chr12_+_21168630 0.04 ENST00000421593.2
SLCO1B7
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr1_-_67390474 0.04 ENST00000371023.3
ENST00000371022.3
ENST00000371026.3
ENST00000431318.1
WDR78
WD repeat domain 78
chr16_-_11617444 0.04 ENST00000598234.1
CTD-3088G3.8
Protein LOC388210
chr4_-_90757364 0.04 ENST00000508895.1
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr1_+_52082751 0.04 ENST00000447887.1
ENST00000435686.2
ENST00000428468.1
ENST00000453295.1
OSBPL9
oxysterol binding protein-like 9
chr8_-_101730061 0.03 ENST00000519100.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chr12_+_7022909 0.03 ENST00000537688.1
ENO2
enolase 2 (gamma, neuronal)
chr2_-_190044480 0.03 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr11_-_126174186 0.03 ENST00000524964.1
RP11-712L6.5
Uncharacterized protein
chr3_-_150264272 0.03 ENST00000491660.1
ENST00000487153.1
ENST00000239944.2
SERP1
stress-associated endoplasmic reticulum protein 1
chr19_+_13051206 0.03 ENST00000586760.1
CALR
calreticulin
chr19_-_41356347 0.03 ENST00000301141.5
CYP2A6
cytochrome P450, family 2, subfamily A, polypeptide 6
chr19_-_45735138 0.03 ENST00000252482.3
EXOC3L2
exocyst complex component 3-like 2
chr10_-_79397547 0.03 ENST00000481070.1
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr16_+_21608525 0.03 ENST00000567404.1
METTL9
methyltransferase like 9
chr16_+_85645007 0.03 ENST00000405402.2
GSE1
Gse1 coiled-coil protein
chrX_-_30993201 0.03 ENST00000288422.2
ENST00000378932.2
TAB3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr8_-_79717750 0.03 ENST00000263851.4
ENST00000379113.2
IL7
interleukin 7
chr2_+_176995011 0.03 ENST00000548663.1
ENST00000450510.2
HOXD8
homeobox D8
chr16_+_66429358 0.03 ENST00000539168.1
CDH5
cadherin 5, type 2 (vascular endothelium)
chr7_-_27135591 0.03 ENST00000343060.4
ENST00000355633.5
HOXA1
homeobox A1
chr11_+_133902547 0.03 ENST00000529070.1
RP11-713P17.3
RP11-713P17.3
chr2_+_54684327 0.03 ENST00000389980.3
SPTBN1
spectrin, beta, non-erythrocytic 1
chr1_+_67390578 0.02 ENST00000371018.3
ENST00000355977.6
ENST00000357692.2
ENST00000401041.1
ENST00000371016.1
ENST00000371014.1
ENST00000371012.2
MIER1
mesoderm induction early response 1, transcriptional regulator
chr3_+_239652 0.02 ENST00000435603.1
CHL1
cell adhesion molecule L1-like
chr4_-_90756769 0.02 ENST00000345009.4
ENST00000505199.1
ENST00000502987.1
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr19_-_49944806 0.02 ENST00000221485.3
SLC17A7
solute carrier family 17 (vesicular glutamate transporter), member 7
chr1_-_109584608 0.02 ENST00000400794.3
ENST00000528747.1
ENST00000369962.3
ENST00000361054.3
WDR47
WD repeat domain 47
chr5_-_179045199 0.02 ENST00000523921.1
HNRNPH1
heterogeneous nuclear ribonucleoprotein H1 (H)
chr16_-_49890016 0.02 ENST00000563137.2
ZNF423
zinc finger protein 423
chr9_+_132099158 0.02 ENST00000444125.1
RP11-65J3.1
RP11-65J3.1
chr17_-_42277203 0.02 ENST00000587097.1
ATXN7L3
ataxin 7-like 3
chr20_+_34742650 0.02 ENST00000373945.1
ENST00000338074.2
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr10_-_105615164 0.02 ENST00000355946.2
ENST00000369774.4
SH3PXD2A
SH3 and PX domains 2A
chr20_+_42574317 0.02 ENST00000358131.5
TOX2
TOX high mobility group box family member 2
chr9_+_40028620 0.02 ENST00000426179.1
AL353791.1
AL353791.1
chr2_+_114647504 0.02 ENST00000263238.2
ACTR3
ARP3 actin-related protein 3 homolog (yeast)
chrX_+_95939711 0.02 ENST00000373049.4
ENST00000324765.8
DIAPH2
diaphanous-related formin 2
chr7_-_86595190 0.02 ENST00000398276.2
ENST00000416314.1
ENST00000425689.1
KIAA1324L
KIAA1324-like
chr12_-_86650077 0.02 ENST00000552808.2
ENST00000547225.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr18_+_18943554 0.02 ENST00000580732.2
GREB1L
growth regulation by estrogen in breast cancer-like
chr17_+_79495397 0.02 ENST00000417245.2
ENST00000334850.7
FSCN2
fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus)
chr1_+_68150744 0.02 ENST00000370986.4
ENST00000370985.3
GADD45A
growth arrest and DNA-damage-inducible, alpha
chr1_-_92351769 0.02 ENST00000212355.4
TGFBR3
transforming growth factor, beta receptor III
chr11_-_2162162 0.02 ENST00000381389.1
IGF2
insulin-like growth factor 2 (somatomedin A)
chr3_-_156877997 0.02 ENST00000295926.3
CCNL1
cyclin L1
chr1_+_178062855 0.02 ENST00000448150.3
RASAL2
RAS protein activator like 2
chr12_+_101988627 0.01 ENST00000547405.1
ENST00000452455.2
ENST00000441232.1
ENST00000360610.2
ENST00000392934.3
ENST00000547509.1
ENST00000361685.2
ENST00000549145.1
ENST00000553190.1
MYBPC1
myosin binding protein C, slow type
chr1_-_109584716 0.01 ENST00000531337.1
ENST00000529074.1
ENST00000369965.4
WDR47
WD repeat domain 47
chr6_+_33387868 0.01 ENST00000418600.2
SYNGAP1
synaptic Ras GTPase activating protein 1
chr19_-_12997995 0.01 ENST00000264834.4
KLF1
Kruppel-like factor 1 (erythroid)
chr7_+_86273218 0.01 ENST00000361669.2
GRM3
glutamate receptor, metabotropic 3
chr1_-_109584768 0.01 ENST00000357672.3
WDR47
WD repeat domain 47
chr2_+_242089833 0.01 ENST00000404405.3
ENST00000439916.1
ENST00000406106.3
ENST00000401987.1
PPP1R7
protein phosphatase 1, regulatory subunit 7
chr11_-_126870655 0.01 ENST00000525144.2
KIRREL3
kin of IRRE like 3 (Drosophila)
chr13_+_97928395 0.01 ENST00000445661.2
MBNL2
muscleblind-like splicing regulator 2
chr2_-_145278475 0.01 ENST00000558170.2
ZEB2
zinc finger E-box binding homeobox 2
chr5_+_167181917 0.01 ENST00000519204.1
TENM2
teneurin transmembrane protein 2
chr1_-_223536679 0.01 ENST00000608996.1
SUSD4
sushi domain containing 4
chr17_-_37353950 0.01 ENST00000394310.3
ENST00000394303.3
ENST00000344140.5
CACNB1
calcium channel, voltage-dependent, beta 1 subunit
chr12_+_7282795 0.01 ENST00000266546.6
CLSTN3
calsyntenin 3
chr2_-_197226875 0.01 ENST00000409111.1
HECW2
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr3_-_98619999 0.01 ENST00000449482.1
DCBLD2
discoidin, CUB and LCCL domain containing 2
chr10_-_65028938 0.01 ENST00000402544.1
JMJD1C
jumonji domain containing 1C
chr14_-_54425475 0.01 ENST00000559642.1
BMP4
bone morphogenetic protein 4
chr12_+_101988774 0.01 ENST00000545503.2
ENST00000536007.1
ENST00000541119.1
ENST00000361466.2
ENST00000551300.1
ENST00000550270.1
MYBPC1
myosin binding protein C, slow type
chr15_+_81591757 0.01 ENST00000558332.1
IL16
interleukin 16
chr17_+_1173853 0.01 ENST00000391429.1
BHLHA9
basic helix-loop-helix family, member a9
chr15_-_74501310 0.01 ENST00000423167.2
ENST00000432245.2
STRA6
stimulated by retinoic acid 6
chr6_+_32006159 0.01 ENST00000478281.1
ENST00000471671.1
ENST00000435122.2
CYP21A2
cytochrome P450, family 21, subfamily A, polypeptide 2
chr12_-_118490217 0.01 ENST00000542304.1
WSB2
WD repeat and SOCS box containing 2
chr16_+_15596123 0.01 ENST00000452191.2
C16orf45
chromosome 16 open reading frame 45
chr17_+_58755184 0.01 ENST00000589222.1
ENST00000407086.3
ENST00000390652.5
BCAS3
breast carcinoma amplified sequence 3
chr9_-_73029540 0.01 ENST00000377126.2
KLF9
Kruppel-like factor 9
chr6_-_113754604 0.01 ENST00000421737.1
RP1-124C6.1
RP1-124C6.1
chr7_+_79765071 0.01 ENST00000457358.2
GNAI1
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr12_+_57482877 0.01 ENST00000342556.6
ENST00000357680.4
NAB2
NGFI-A binding protein 2 (EGR1 binding protein 2)
chr1_+_243419306 0.01 ENST00000355875.4
ENST00000391846.1
ENST00000366541.3
ENST00000343783.6
SDCCAG8
serologically defined colon cancer antigen 8
chr19_-_51512804 0.01 ENST00000594211.1
ENST00000376832.4
KLK9
kallikrein-related peptidase 9
chr20_+_30467600 0.01 ENST00000375934.4
ENST00000375922.4
TTLL9
tubulin tyrosine ligase-like family, member 9
chr14_-_24733444 0.00 ENST00000560478.1
ENST00000560443.1
TGM1
transglutaminase 1
chr3_+_191046810 0.00 ENST00000392455.3
ENST00000392456.3
CCDC50
coiled-coil domain containing 50
chr2_-_44588694 0.00 ENST00000409957.1
PREPL
prolyl endopeptidase-like
chr12_+_57610562 0.00 ENST00000349394.5
NXPH4
neurexophilin 4
chr9_-_101471479 0.00 ENST00000259455.2
GABBR2
gamma-aminobutyric acid (GABA) B receptor, 2
chr15_-_64673630 0.00 ENST00000558008.1
ENST00000559519.1
ENST00000380258.2
KIAA0101
KIAA0101
chr2_-_44588679 0.00 ENST00000409411.1
PREPL
prolyl endopeptidase-like
chr13_+_52586517 0.00 ENST00000523764.1
ENST00000521508.1
ALG11
ALG11, alpha-1,2-mannosyltransferase
chr8_+_22250334 0.00 ENST00000520832.1
SLC39A14
solute carrier family 39 (zinc transporter), member 14
chr2_+_26624775 0.00 ENST00000288710.2
DRC1
dynein regulatory complex subunit 1 homolog (Chlamydomonas)
chr11_-_93583697 0.00 ENST00000409977.1
VSTM5
V-set and transmembrane domain containing 5
chr1_-_65533390 0.00 ENST00000448344.1
RP4-535B20.1
RP4-535B20.1
chr10_+_95848824 0.00 ENST00000371385.3
ENST00000371375.1
PLCE1
phospholipase C, epsilon 1
chrX_-_110655306 0.00 ENST00000371993.2
DCX
doublecortin
chr15_+_48009541 0.00 ENST00000536845.2
ENST00000558816.1
SEMA6D
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr15_-_74501360 0.00 ENST00000323940.5
STRA6
stimulated by retinoic acid 6
chr2_-_145277882 0.00 ENST00000465070.1
ENST00000444559.1
ZEB2
zinc finger E-box binding homeobox 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.0 0.0 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
0.0 0.1 GO:0060979 transforming growth factor beta receptor complex assembly(GO:0007181) vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.0 0.0 GO:0045081 negative regulation of interleukin-10 biosynthetic process(GO:0045081)
0.0 0.1 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.1 GO:0051620 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.0 0.0 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.1 GO:0030581 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.0 GO:0005588 collagen type V trimer(GO:0005588)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0070123 transforming growth factor beta receptor activity, type III(GO:0070123)
0.0 0.0 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)
0.0 0.1 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.1 GO:0060961 phospholipase D inhibitor activity(GO:0060961)