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avrg: A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for TFEC_MITF_ARNTL_BHLHE41

Z-value: 0.28

Motif logo

Transcription factors associated with TFEC_MITF_ARNTL_BHLHE41

Gene Symbol Gene ID Gene Info
ENSG00000105967.11 TFEC
ENSG00000187098.10 MITF
ENSG00000133794.13 ARNTL
ENSG00000123095.5 BHLHE41

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MITFhg19_v2_chr3_+_69985792_69985874-0.955.3e-02Click!
BHLHE41hg19_v2_chr12_-_26278030_26278060-0.524.8e-01Click!
TFEChg19_v2_chr7_-_115670792_1156707980.336.7e-01Click!
ARNTLhg19_v2_chr11_+_13299186_13299432-0.297.1e-01Click!

Activity profile of TFEC_MITF_ARNTL_BHLHE41 motif

Sorted Z-values of TFEC_MITF_ARNTL_BHLHE41 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of TFEC_MITF_ARNTL_BHLHE41

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr12_-_58145889 1.76 ENST00000547853.1
CDK4
cyclin-dependent kinase 4
chr17_-_6915616 1.06 ENST00000575889.1
AC027763.2
Uncharacterized protein
chr13_+_113951607 0.99 ENST00000397181.3
LAMP1
lysosomal-associated membrane protein 1
chr17_-_7137582 0.91 ENST00000575756.1
ENST00000575458.1
DVL2
dishevelled segment polarity protein 2
chr12_+_123849462 0.90 ENST00000543072.1
hsa-mir-8072
hsa-mir-8072
chr1_-_42921915 0.90 ENST00000372565.3
ENST00000433602.2
ZMYND12
zinc finger, MYND-type containing 12
chr12_+_56109926 0.84 ENST00000547076.1
BLOC1S1
biogenesis of lysosomal organelles complex-1, subunit 1
chrX_-_100662881 0.77 ENST00000218516.3
GLA
galactosidase, alpha
chr17_-_7137857 0.75 ENST00000005340.5
DVL2
dishevelled segment polarity protein 2
chr12_-_58146048 0.74 ENST00000547281.1
ENST00000546489.1
ENST00000552388.1
ENST00000540325.1
ENST00000312990.6
CDK4
cyclin-dependent kinase 4
chr10_-_46089939 0.73 ENST00000453980.3
MARCH8
membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
chr19_+_49458107 0.71 ENST00000539787.1
ENST00000345358.7
ENST00000391871.3
ENST00000415969.2
ENST00000354470.3
ENST00000506183.1
ENST00000293288.8
BAX
BCL2-associated X protein
chr12_+_56110247 0.69 ENST00000551926.1
BLOC1S1
biogenesis of lysosomal organelles complex-1, subunit 1
chr2_-_220042825 0.67 ENST00000409789.1
CNPPD1
cyclin Pas1/PHO80 domain containing 1
chr14_-_81687575 0.65 ENST00000434192.2
GTF2A1
general transcription factor IIA, 1, 19/37kDa
chr12_-_58146128 0.60 ENST00000551800.1
ENST00000549606.1
ENST00000257904.6
CDK4
cyclin-dependent kinase 4
chr1_+_11866270 0.60 ENST00000376497.3
ENST00000376487.3
ENST00000376496.3
CLCN6
chloride channel, voltage-sensitive 6
chr12_+_56110315 0.59 ENST00000548556.1
BLOC1S1
biogenesis of lysosomal organelles complex-1, subunit 1
chr19_+_4402659 0.56 ENST00000301280.5
ENST00000585854.1
CHAF1A
chromatin assembly factor 1, subunit A (p150)
chr16_+_28985542 0.50 ENST00000567771.1
ENST00000568388.1
SPNS1
spinster homolog 1 (Drosophila)
chrX_-_118699325 0.50 ENST00000320339.4
ENST00000371594.4
ENST00000536133.1
CXorf56
chromosome X open reading frame 56
chr1_-_166845515 0.49 ENST00000367874.4
TADA1
transcriptional adaptor 1
chr1_-_154193009 0.49 ENST00000368518.1
ENST00000368519.1
ENST00000368521.5
C1orf43
chromosome 1 open reading frame 43
chr7_-_27205136 0.49 ENST00000396345.1
ENST00000343483.6
HOXA9
homeobox A9
chr19_-_10426663 0.49 ENST00000541276.1
ENST00000393708.3
ENST00000494368.1
FDX1L
ferredoxin 1-like
chr1_+_92414952 0.48 ENST00000449584.1
ENST00000427104.1
ENST00000355011.3
ENST00000448194.1
ENST00000426141.1
ENST00000450792.1
ENST00000548992.1
ENST00000552654.1
ENST00000457265.1
BRDT
bromodomain, testis-specific
chr1_-_154193091 0.48 ENST00000362076.4
ENST00000350592.3
ENST00000368516.1
C1orf43
chromosome 1 open reading frame 43
chr19_+_10764937 0.47 ENST00000449870.1
ENST00000318511.3
ENST00000420083.1
ILF3
interleukin enhancer binding factor 3, 90kDa
chr16_-_28503357 0.47 ENST00000333496.9
ENST00000561505.1
ENST00000567963.1
ENST00000354630.5
ENST00000355477.5
ENST00000357076.5
ENST00000565688.1
ENST00000359984.7
CLN3
ceroid-lipofuscinosis, neuronal 3
chr2_+_220042933 0.46 ENST00000430297.2
FAM134A
family with sequence similarity 134, member A
chr22_-_39268308 0.46 ENST00000407418.3
CBX6
chromobox homolog 6
chr16_-_28503327 0.45 ENST00000535392.1
ENST00000395653.4
CLN3
ceroid-lipofuscinosis, neuronal 3
chr6_-_33385823 0.45 ENST00000494751.1
ENST00000374496.3
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr19_-_40854417 0.44 ENST00000582006.1
ENST00000582783.1
C19orf47
chromosome 19 open reading frame 47
chr1_-_155211065 0.44 ENST00000427500.3
GBA
glucosidase, beta, acid
chr1_-_11866034 0.44 ENST00000376590.3
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr1_-_155211017 0.43 ENST00000536770.1
ENST00000368373.3
GBA
glucosidase, beta, acid
chr2_+_27309605 0.43 ENST00000260599.6
ENST00000260598.5
ENST00000429697.1
KHK
ketohexokinase (fructokinase)
chr3_+_113465866 0.42 ENST00000273398.3
ENST00000538620.1
ENST00000496747.1
ENST00000475322.1
ATP6V1A
ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
chr12_+_56109810 0.42 ENST00000550412.1
ENST00000257899.2
ENST00000548925.1
ENST00000549147.1
RP11-644F5.10
BLOC1S1
Uncharacterized protein
biogenesis of lysosomal organelles complex-1, subunit 1
chr17_+_18218587 0.41 ENST00000406438.3
SMCR8
Smith-Magenis syndrome chromosome region, candidate 8
chr16_-_28503080 0.41 ENST00000565316.1
ENST00000565778.1
ENST00000357857.9
ENST00000568558.1
ENST00000357806.7
CLN3
ceroid-lipofuscinosis, neuronal 3
chr17_-_48450265 0.41 ENST00000507088.1
MRPL27
mitochondrial ribosomal protein L27
chr19_+_10812108 0.40 ENST00000250237.5
ENST00000592254.1
QTRT1
queuine tRNA-ribosyltransferase 1
chr17_-_48450534 0.40 ENST00000503633.1
ENST00000442592.3
ENST00000225969.4
MRPL27
mitochondrial ribosomal protein L27
chr12_-_90103077 0.40 ENST00000551310.1
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr15_+_44084503 0.40 ENST00000409960.2
ENST00000409646.1
ENST00000594896.1
ENST00000339624.5
ENST00000409291.1
ENST00000402131.1
ENST00000403425.1
ENST00000430901.1
SERF2
small EDRK-rich factor 2
chr12_-_122751002 0.39 ENST00000267199.4
VPS33A
vacuolar protein sorting 33 homolog A (S. cerevisiae)
chr7_+_100464760 0.39 ENST00000200457.4
TRIP6
thyroid hormone receptor interactor 6
chr7_+_99746514 0.39 ENST00000341942.5
ENST00000441173.1
LAMTOR4
late endosomal/lysosomal adaptor, MAPK and MTOR activator 4
chr19_+_41305406 0.37 ENST00000406058.2
ENST00000593726.1
EGLN2
egl-9 family hypoxia-inducible factor 2
chr6_+_160390102 0.37 ENST00000356956.1
IGF2R
insulin-like growth factor 2 receptor
chr17_-_6915646 0.36 ENST00000574377.1
ENST00000399541.2
ENST00000399540.2
ENST00000575727.1
ENST00000573939.1
AC027763.2
Uncharacterized protein
chr12_+_51633061 0.35 ENST00000551313.1
DAZAP2
DAZ associated protein 2
chr13_+_113951532 0.35 ENST00000332556.4
LAMP1
lysosomal-associated membrane protein 1
chr9_-_100684845 0.35 ENST00000375119.3
C9orf156
chromosome 9 open reading frame 156
chr22_-_36903069 0.35 ENST00000216187.6
ENST00000423980.1
FOXRED2
FAD-dependent oxidoreductase domain containing 2
chr17_+_1627834 0.35 ENST00000419248.1
ENST00000418841.1
WDR81
WD repeat domain 81
chr15_+_44084040 0.35 ENST00000249786.4
SERF2
small EDRK-rich factor 2
chr19_-_10764509 0.35 ENST00000591501.1
ILF3-AS1
ILF3 antisense RNA 1 (head to head)
chr15_+_75628232 0.34 ENST00000267935.8
ENST00000567195.1
COMMD4
COMM domain containing 4
chr15_+_75628419 0.34 ENST00000567377.1
ENST00000562789.1
ENST00000568301.1
COMMD4
COMM domain containing 4
chr6_-_36953833 0.34 ENST00000538808.1
ENST00000460219.1
ENST00000373616.5
ENST00000373627.5
MTCH1
mitochondrial carrier 1
chr18_-_2982869 0.33 ENST00000584915.1
LPIN2
lipin 2
chr5_-_110074603 0.33 ENST00000515278.2
TMEM232
transmembrane protein 232
chr12_+_54426637 0.33 ENST00000312492.2
HOXC5
homeobox C5
chr20_+_37590942 0.33 ENST00000373325.2
ENST00000252011.3
ENST00000373323.4
DHX35
DEAH (Asp-Glu-Ala-His) box polypeptide 35
chr9_+_131709966 0.32 ENST00000372577.2
NUP188
nucleoporin 188kDa
chr16_-_5083589 0.32 ENST00000563578.1
ENST00000562346.2
NAGPA
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr5_-_176730676 0.31 ENST00000393611.2
ENST00000303251.6
ENST00000303270.6
RAB24
RAB24, member RAS oncogene family
chr5_-_150138246 0.31 ENST00000518015.1
DCTN4
dynactin 4 (p62)
chr16_+_88923494 0.31 ENST00000567895.1
ENST00000301021.3
ENST00000565504.1
ENST00000567312.1
ENST00000568583.1
ENST00000561840.1
TRAPPC2L
trafficking protein particle complex 2-like
chr10_-_25305011 0.31 ENST00000331161.4
ENST00000376363.1
ENKUR
enkurin, TRPC channel interacting protein
chr19_+_5681153 0.31 ENST00000579559.1
ENST00000577222.1
HSD11B1L
RPL36
hydroxysteroid (11-beta) dehydrogenase 1-like
ribosomal protein L36
chr1_+_22778337 0.31 ENST00000404138.1
ENST00000400239.2
ENST00000375647.4
ENST00000374651.4
ZBTB40
zinc finger and BTB domain containing 40
chr19_+_41305085 0.31 ENST00000303961.4
EGLN2
egl-9 family hypoxia-inducible factor 2
chr22_-_39268192 0.30 ENST00000216083.6
CBX6
chromobox homolog 6
chr11_+_118938485 0.30 ENST00000300793.6
VPS11
vacuolar protein sorting 11 homolog (S. cerevisiae)
chr22_-_42342692 0.29 ENST00000404067.1
ENST00000402338.1
CENPM
centromere protein M
chr3_+_184032419 0.29 ENST00000352767.3
ENST00000427141.2
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chrX_+_102883887 0.29 ENST00000372625.3
ENST00000372624.3
TCEAL1
transcription elongation factor A (SII)-like 1
chr19_+_7587555 0.29 ENST00000601003.1
MCOLN1
mucolipin 1
chr2_-_220083671 0.29 ENST00000439002.2
ABCB6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr19_+_41305330 0.29 ENST00000593972.1
EGLN2
egl-9 family hypoxia-inducible factor 2
chr3_-_4508925 0.28 ENST00000534863.1
ENST00000383843.5
ENST00000458465.2
ENST00000405420.2
ENST00000272902.5
SUMF1
sulfatase modifying factor 1
chr22_-_39096981 0.28 ENST00000427389.1
JOSD1
Josephin domain containing 1
chr10_+_51827648 0.28 ENST00000351071.6
ENST00000314664.7
ENST00000282633.5
FAM21A
family with sequence similarity 21, member A
chr19_-_12833361 0.28 ENST00000592287.1
TNPO2
transportin 2
chr6_+_139349903 0.27 ENST00000461027.1
ABRACL
ABRA C-terminal like
chr11_+_18344106 0.27 ENST00000534641.1
ENST00000525831.1
ENST00000265963.4
GTF2H1
general transcription factor IIH, polypeptide 1, 62kDa
chr17_+_46018872 0.27 ENST00000583599.1
ENST00000434554.2
ENST00000225573.4
ENST00000544840.1
ENST00000534893.1
PNPO
pyridoxamine 5'-phosphate oxidase
chr17_+_48450575 0.27 ENST00000338165.4
ENST00000393271.2
ENST00000511519.2
EME1
essential meiotic structure-specific endonuclease 1
chr3_+_51428704 0.27 ENST00000323686.4
RBM15B
RNA binding motif protein 15B
chr9_-_139137648 0.27 ENST00000358701.5
QSOX2
quiescin Q6 sulfhydryl oxidase 2
chr1_-_52831796 0.27 ENST00000284376.3
ENST00000438831.1
ENST00000371586.2
CC2D1B
coiled-coil and C2 domain containing 1B
chr20_+_44519948 0.27 ENST00000354880.5
ENST00000191018.5
CTSA
cathepsin A
chr1_-_156265438 0.26 ENST00000362007.1
C1orf85
chromosome 1 open reading frame 85
chr16_+_31044413 0.26 ENST00000394998.1
STX4
syntaxin 4
chr1_+_44440575 0.26 ENST00000532642.1
ENST00000236067.4
ENST00000471859.2
ATP6V0B
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr1_+_45477819 0.26 ENST00000246337.4
UROD
uroporphyrinogen decarboxylase
chr1_-_154928562 0.26 ENST00000368463.3
ENST00000539880.1
ENST00000542459.1
ENST00000368460.3
ENST00000368465.1
PBXIP1
pre-B-cell leukemia homeobox interacting protein 1
chr16_+_5083950 0.26 ENST00000588623.1
ALG1
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
chr19_+_47634039 0.26 ENST00000597808.1
ENST00000413379.3
ENST00000600706.1
ENST00000540850.1
ENST00000598840.1
ENST00000600753.1
ENST00000270225.7
ENST00000392776.3
SAE1
SUMO1 activating enzyme subunit 1
chrX_+_100663243 0.26 ENST00000316594.5
HNRNPH2
heterogeneous nuclear ribonucleoprotein H2 (H')
chrX_-_101397433 0.25 ENST00000372774.3
TCEAL6
transcription elongation factor A (SII)-like 6
chr12_+_53645870 0.25 ENST00000329548.4
MFSD5
major facilitator superfamily domain containing 5
chr19_+_10765003 0.25 ENST00000407004.3
ENST00000589998.1
ENST00000589600.1
ILF3
interleukin enhancer binding factor 3, 90kDa
chr12_+_54332535 0.25 ENST00000243056.3
HOXC13
homeobox C13
chr2_-_220083692 0.25 ENST00000265316.3
ABCB6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr10_+_99344104 0.25 ENST00000555577.1
ENST00000370649.3
PI4K2A
PI4K2A
phosphatidylinositol 4-kinase type 2 alpha
Phosphatidylinositol 4-kinase type 2-alpha; Uncharacterized protein
chr20_+_44520009 0.25 ENST00000607482.1
ENST00000372459.2
CTSA
cathepsin A
chr1_-_154909329 0.25 ENST00000368467.3
PMVK
phosphomevalonate kinase
chr17_+_7344057 0.25 ENST00000575398.1
ENST00000575082.1
FGF11
fibroblast growth factor 11
chr11_-_71814276 0.25 ENST00000538404.1
ENST00000535107.1
ENST00000545249.1
LAMTOR1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
chr19_+_5681011 0.24 ENST00000581893.1
ENST00000411793.2
ENST00000301382.4
ENST00000581773.1
ENST00000423665.2
ENST00000583928.1
ENST00000342970.2
ENST00000422535.2
ENST00000581521.1
ENST00000339423.2
HSD11B1L
hydroxysteroid (11-beta) dehydrogenase 1-like
chr19_+_8386371 0.24 ENST00000600659.2
RPS28
ribosomal protein S28
chr19_-_15236562 0.24 ENST00000263383.3
ILVBL
ilvB (bacterial acetolactate synthase)-like
chr5_+_150827143 0.24 ENST00000243389.3
ENST00000517945.1
ENST00000521925.1
SLC36A1
solute carrier family 36 (proton/amino acid symporter), member 1
chr15_+_75628394 0.24 ENST00000564815.1
ENST00000338995.6
COMMD4
COMM domain containing 4
chr16_-_70323422 0.24 ENST00000261772.8
AARS
alanyl-tRNA synthetase
chr14_-_94443105 0.24 ENST00000555019.1
ASB2
ankyrin repeat and SOCS box containing 2
chr19_+_12848299 0.23 ENST00000357332.3
ASNA1
arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
chr17_-_30185946 0.23 ENST00000579741.1
COPRS
coordinator of PRMT5, differentiation stimulator
chr19_-_40854281 0.23 ENST00000392035.2
C19orf47
chromosome 19 open reading frame 47
chr6_-_33385655 0.23 ENST00000440279.3
ENST00000607266.1
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr19_+_14544099 0.23 ENST00000242783.6
ENST00000586557.1
ENST00000590097.1
PKN1
protein kinase N1
chr11_+_777562 0.23 ENST00000530083.1
AP006621.5
Protein LOC100506518
chr19_-_19739321 0.23 ENST00000588461.1
LPAR2
lysophosphatidic acid receptor 2
chr16_+_9185450 0.23 ENST00000327827.7
C16orf72
chromosome 16 open reading frame 72
chr17_+_73975292 0.23 ENST00000397640.1
ENST00000416485.1
ENST00000588202.1
ENST00000590676.1
ENST00000586891.1
TEN1
TEN1 CST complex subunit
chr2_+_240323439 0.23 ENST00000428471.1
ENST00000413029.1
AC062017.1
Uncharacterized protein
chr19_+_35810164 0.23 ENST00000598537.1
CD22
CD22 molecule
chr11_+_126081662 0.22 ENST00000528985.1
ENST00000529731.1
ENST00000360194.4
ENST00000530043.1
FAM118B
family with sequence similarity 118, member B
chr16_-_68269971 0.22 ENST00000565858.1
ESRP2
epithelial splicing regulatory protein 2
chr7_+_100271446 0.22 ENST00000419828.1
ENST00000427895.1
GNB2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chrX_-_102319092 0.22 ENST00000372728.3
BEX1
brain expressed, X-linked 1
chr16_+_28986085 0.22 ENST00000565975.1
ENST00000311008.11
ENST00000323081.8
ENST00000334536.8
SPNS1
spinster homolog 1 (Drosophila)
chr16_-_5083917 0.22 ENST00000312251.3
ENST00000381955.3
NAGPA
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr14_-_68283291 0.22 ENST00000555452.1
ENST00000347230.4
ZFYVE26
zinc finger, FYVE domain containing 26
chr3_+_184032313 0.22 ENST00000392537.2
ENST00000444134.1
ENST00000450424.1
ENST00000421110.1
ENST00000382330.3
ENST00000426123.1
ENST00000350481.5
ENST00000455679.1
ENST00000440448.1
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr16_+_29127282 0.22 ENST00000562902.1
RP11-426C22.5
RP11-426C22.5
chr14_-_20929624 0.22 ENST00000398020.4
ENST00000250489.4
TMEM55B
transmembrane protein 55B
chr19_+_6464502 0.22 ENST00000308243.7
CRB3
crumbs homolog 3 (Drosophila)
chr16_+_69796209 0.22 ENST00000359154.2
ENST00000561780.1
ENST00000563659.1
ENST00000448661.1
WWP2
WW domain containing E3 ubiquitin protein ligase 2
chr4_-_100871506 0.21 ENST00000296417.5
H2AFZ
H2A histone family, member Z
chr19_+_6464243 0.21 ENST00000600229.1
ENST00000356762.3
CRB3
crumbs homolog 3 (Drosophila)
chr8_+_98656336 0.21 ENST00000336273.3
MTDH
metadherin
chr10_-_18948208 0.21 ENST00000607346.1
ARL5B-AS1
ARL5B antisense RNA 1
chr4_-_120222076 0.21 ENST00000504110.1
C4orf3
chromosome 4 open reading frame 3
chr1_-_198906528 0.21 ENST00000432296.1
MIR181A1HG
MIR181A1 host gene (non-protein coding)
chr19_+_49990811 0.21 ENST00000391857.4
ENST00000467825.2
RPL13A
ribosomal protein L13a
chr19_-_15236470 0.21 ENST00000533747.1
ENST00000598709.1
ENST00000534378.1
ILVBL
ilvB (bacterial acetolactate synthase)-like
chr22_+_40573921 0.21 ENST00000454349.2
ENST00000335727.9
TNRC6B
trinucleotide repeat containing 6B
chr11_-_36310958 0.21 ENST00000532705.1
ENST00000263401.5
ENST00000452374.2
COMMD9
COMM domain containing 9
chr22_-_50700140 0.20 ENST00000215659.8
MAPK12
mitogen-activated protein kinase 12
chr1_+_45477901 0.20 ENST00000434478.1
UROD
uroporphyrinogen decarboxylase
chr10_+_46222648 0.20 ENST00000336378.4
ENST00000540872.1
ENST00000537517.1
ENST00000374362.2
ENST00000359860.4
ENST00000420848.1
FAM21C
family with sequence similarity 21, member C
chr16_-_70719925 0.20 ENST00000338779.6
MTSS1L
metastasis suppressor 1-like
chr17_+_17876127 0.20 ENST00000582416.1
ENST00000313838.8
ENST00000411504.2
ENST00000581264.1
ENST00000399187.1
ENST00000479684.2
ENST00000584166.1
ENST00000585108.1
ENST00000399182.1
ENST00000579977.1
LRRC48
leucine rich repeat containing 48
chr1_-_11865982 0.20 ENST00000418034.1
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr17_+_78075361 0.20 ENST00000577106.1
ENST00000390015.3
GAA
glucosidase, alpha; acid
chr7_-_99699538 0.20 ENST00000343023.6
ENST00000303887.5
MCM7
minichromosome maintenance complex component 7
chr15_-_72668805 0.20 ENST00000268097.5
HEXA
hexosaminidase A (alpha polypeptide)
chr10_-_82049424 0.20 ENST00000372213.3
MAT1A
methionine adenosyltransferase I, alpha
chr1_-_27226928 0.20 ENST00000361720.5
GPATCH3
G patch domain containing 3
chr12_+_53400176 0.20 ENST00000551002.1
ENST00000420463.3
ENST00000416762.3
ENST00000549481.1
ENST00000552490.1
EIF4B
eukaryotic translation initiation factor 4B
chr3_+_184032283 0.20 ENST00000346169.2
ENST00000414031.1
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr9_-_90589586 0.19 ENST00000325303.8
ENST00000375883.3
CDK20
cyclin-dependent kinase 20
chr7_+_99775366 0.19 ENST00000394018.2
ENST00000416412.1
STAG3
stromal antigen 3
chr20_+_2821366 0.19 ENST00000453689.1
ENST00000417508.1
VPS16
vacuolar protein sorting 16 homolog (S. cerevisiae)
chr16_-_58718611 0.19 ENST00000564100.1
ENST00000570101.1
SLC38A7
solute carrier family 38, member 7
chr12_-_2986107 0.19 ENST00000359843.3
ENST00000342628.2
ENST00000361953.3
FOXM1
forkhead box M1
chr14_+_77564701 0.19 ENST00000557115.1
KIAA1737
CLOCK-interacting pacemaker
chr9_-_131709858 0.19 ENST00000372586.3
DOLK
dolichol kinase
chr17_+_42977062 0.19 ENST00000410006.2
ENST00000357776.2
ENST00000410027.1
CCDC103
coiled-coil domain containing 103
chr16_-_67514982 0.19 ENST00000565835.1
ENST00000540149.1
ENST00000290949.3
ATP6V0D1
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
chr9_+_136325149 0.19 ENST00000542192.1
CACFD1
calcium channel flower domain containing 1
chr7_+_116593568 0.19 ENST00000446490.1
ST7
suppression of tumorigenicity 7
chr19_-_5719860 0.19 ENST00000590729.1
LONP1
lon peptidase 1, mitochondrial
chr10_+_52751010 0.19 ENST00000373985.1
PRKG1
protein kinase, cGMP-dependent, type I
chr12_+_54366894 0.19 ENST00000546378.1
ENST00000243082.4
HOXC11
homeobox C11
chr10_+_99258625 0.19 ENST00000370664.3
UBTD1
ubiquitin domain containing 1
chr22_-_42343117 0.18 ENST00000407253.3
ENST00000215980.5
CENPM
centromere protein M
chr19_-_1237990 0.18 ENST00000382477.2
ENST00000215376.6
ENST00000590083.1
C19orf26
chromosome 19 open reading frame 26
chrX_+_118108571 0.18 ENST00000304778.7
LONRF3
LON peptidase N-terminal domain and ring finger 3
chr2_-_131850951 0.18 ENST00000409185.1
ENST00000389915.3
FAM168B
family with sequence similarity 168, member B
chr17_+_62503073 0.18 ENST00000580188.1
ENST00000581056.1
CEP95
centrosomal protein 95kDa
chr19_-_5340730 0.18 ENST00000372412.4
ENST00000357368.4
ENST00000262963.6
ENST00000348075.2
ENST00000353284.2
PTPRS
protein tyrosine phosphatase, receptor type, S
chr5_-_1799965 0.18 ENST00000508987.1
MRPL36
mitochondrial ribosomal protein L36
chr4_-_110736505 0.18 ENST00000609440.1
RP11-602N24.3
RP11-602N24.3
chr10_-_120840309 0.18 ENST00000369144.3
EIF3A
eukaryotic translation initiation factor 3, subunit A
chr1_-_154531095 0.17 ENST00000292211.4
UBE2Q1
ubiquitin-conjugating enzyme E2Q family member 1
chr17_-_18218237 0.17 ENST00000542570.1
TOP3A
topoisomerase (DNA) III alpha
chr1_+_11866207 0.17 ENST00000312413.6
ENST00000346436.6
CLCN6
chloride channel, voltage-sensitive 6
chr5_+_34656450 0.17 ENST00000514527.1
RAI14
retinoic acid induced 14
chr15_-_72668185 0.17 ENST00000457859.2
ENST00000566304.1
ENST00000567159.1
ENST00000429918.2
HEXA
hexosaminidase A (alpha polypeptide)
chrX_+_129040094 0.17 ENST00000425117.2
UTP14A
UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
chr17_+_42422629 0.17 ENST00000589536.1
ENST00000587109.1
ENST00000587518.1
GRN
granulin
chr9_-_37576226 0.17 ENST00000432825.2
FBXO10
F-box protein 10
chr8_-_107782463 0.17 ENST00000311955.3
ABRA
actin-binding Rho activating protein

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.4 3.3 GO:1904637 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.3 1.3 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.3 1.3 GO:0043323 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.2 0.7 GO:0002352 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597) positive regulation of apoptotic DNA fragmentation(GO:1902512)
0.2 0.9 GO:1901805 beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.2 0.5 GO:0051037 regulation of transcription involved in meiotic cell cycle(GO:0051037)
0.2 2.6 GO:0060155 platelet dense granule organization(GO:0060155)
0.1 0.4 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
0.1 0.6 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.1 0.4 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.1 0.8 GO:0016139 glycoside catabolic process(GO:0016139)
0.1 0.3 GO:0002276 basophil activation involved in immune response(GO:0002276) basophil activation(GO:0045575)
0.1 0.2 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.2 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 0.2 GO:1902568 regulation of eosinophil degranulation(GO:0043309) positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.1 0.4 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1 0.4 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1 0.3 GO:0042823 pyridoxal phosphate biosynthetic process(GO:0042823)
0.1 0.9 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1 0.6 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.1 0.2 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.1 0.2 GO:0090301 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.1 0.2 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.1 0.2 GO:0002188 translation reinitiation(GO:0002188)
0.1 0.2 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.1 0.2 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.1 0.2 GO:1902559 3'-phosphoadenosine 5'-phosphosulfate transport(GO:0046963) 3'-phospho-5'-adenylyl sulfate transmembrane transport(GO:1902559)
0.1 0.2 GO:0060168 positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.1 0.3 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.1 0.2 GO:0043181 vacuolar sequestering(GO:0043181)
0.1 0.8 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.2 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.0 0.2 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.5 GO:0015808 L-alanine transport(GO:0015808)
0.0 1.0 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.4 GO:1990034 cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034)
0.0 0.2 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.5 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process(GO:0046901)
0.0 0.1 GO:0006258 UDP-glucose catabolic process(GO:0006258)
0.0 0.1 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.0 0.1 GO:0043474 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0 0.6 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.1 GO:0021882 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) regulation of amacrine cell differentiation(GO:1902869) positive regulation of amacrine cell differentiation(GO:1902871)
0.0 0.2 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 0.0 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.3 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.0 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.0 0.1 GO:1901207 regulation of heart looping(GO:1901207)
0.0 0.1 GO:0009786 regulation of asymmetric cell division(GO:0009786) mesonephric duct morphogenesis(GO:0072180)
0.0 0.4 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.4 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0 0.2 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.0 0.1 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.0 0.4 GO:0071907 determination of digestive tract left/right asymmetry(GO:0071907)
0.0 0.2 GO:0006489 dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
0.0 0.5 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.1 GO:0006059 hexitol metabolic process(GO:0006059)
0.0 0.0 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.0 0.1 GO:0061433 cellular response to caloric restriction(GO:0061433) negative regulation of oligodendrocyte progenitor proliferation(GO:0070446)
0.0 0.2 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.2 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.2 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
0.0 0.4 GO:0060613 fat pad development(GO:0060613)
0.0 0.1 GO:0070495 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495) negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0 0.2 GO:0045445 myoblast differentiation(GO:0045445)
0.0 0.1 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.1 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.1 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.0 0.1 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.0 0.7 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.0 0.5 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.5 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.5 GO:0015886 heme transport(GO:0015886)
0.0 0.1 GO:0006043 glucosamine catabolic process(GO:0006043)
0.0 0.3 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.1 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.1 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.0 0.0 GO:0048565 digestive tract development(GO:0048565)
0.0 0.3 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.4 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.1 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.0 0.1 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.0 0.3 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.0 0.2 GO:0032490 detection of molecule of bacterial origin(GO:0032490)
0.0 0.2 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.1 GO:0006147 guanine catabolic process(GO:0006147)
0.0 0.1 GO:0046709 IDP metabolic process(GO:0046707) IDP catabolic process(GO:0046709)
0.0 0.1 GO:0032900 viral protein processing(GO:0019082) negative regulation of neurotrophin production(GO:0032900) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.0 0.1 GO:0070309 positive regulation by virus of viral protein levels in host cell(GO:0046726) lens fiber cell morphogenesis(GO:0070309)
0.0 0.2 GO:1990834 response to odorant(GO:1990834)
0.0 0.1 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.1 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.0 0.1 GO:2000775 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775)
0.0 0.1 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.1 GO:0034059 response to anoxia(GO:0034059)
0.0 0.8 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.0 0.1 GO:2000657 regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657)
0.0 0.3 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0 0.1 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.2 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.0 0.1 GO:2000538 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.0 0.2 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.0 0.1 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.1 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
0.0 0.2 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.1 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.9 GO:0034724 DNA replication-independent nucleosome organization(GO:0034724)
0.0 0.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.1 GO:0060620 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0 0.8 GO:0033572 transferrin transport(GO:0033572)
0.0 0.2 GO:0070459 prolactin secretion(GO:0070459)
0.0 0.1 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.1 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.0 0.1 GO:1902683 positive regulation of long-term neuronal synaptic plasticity(GO:0048170) regulation of receptor localization to synapse(GO:1902683)
0.0 0.3 GO:0035878 nail development(GO:0035878)
0.0 0.1 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.3 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.1 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.1 GO:0006788 heme oxidation(GO:0006788) negative regulation of mast cell cytokine production(GO:0032764) regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.0 0.1 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.0 0.1 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
0.0 0.0 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:2000506 negative regulation of energy homeostasis(GO:2000506)
0.0 0.4 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.3 GO:0006265 DNA topological change(GO:0006265)
0.0 0.1 GO:0032053 ciliary basal body organization(GO:0032053) positive regulation of protein localization to cilium(GO:1903566)
0.0 0.2 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.0 0.1 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.0 0.0 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.1 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.3 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.0 0.1 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.2 GO:2000615 regulation of histone H3-K9 acetylation(GO:2000615)
0.0 0.2 GO:0046321 positive regulation of fatty acid oxidation(GO:0046321)
0.0 0.1 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.1 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.2 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.0 GO:0002840 T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840)
0.0 0.0 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.0 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.0 0.1 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:1902904 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.0 0.1 GO:0045900 negative regulation of translational elongation(GO:0045900)
0.0 0.1 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501)
0.0 0.2 GO:0030575 nuclear body organization(GO:0030575)
0.0 0.3 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.1 GO:0036506 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.0 0.1 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.0 GO:0044209 AMP salvage(GO:0044209)
0.0 0.1 GO:1900368 regulation of RNA interference(GO:1900368)
0.0 0.2 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.0 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.0 0.0 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.0 GO:0019516 lactate oxidation(GO:0019516)
0.0 0.0 GO:1902903 regulation of fibril organization(GO:1902903)
0.0 0.0 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.0 0.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.2 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.1 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.2 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 1.3 GO:0044194 cytolytic granule(GO:0044194)
0.1 0.5 GO:0033186 CAF-1 complex(GO:0033186)
0.1 0.3 GO:0043614 multi-eIF complex(GO:0043614)
0.1 0.3 GO:0044279 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.1 0.6 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.1 0.3 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 2.5 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 0.4 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.1 0.6 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 0.3 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.1 0.7 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.3 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.3 GO:0071817 MMXD complex(GO:0071817)
0.0 0.1 GO:0001534 radial spoke(GO:0001534)
0.0 0.5 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.8 GO:0030897 HOPS complex(GO:0030897)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.5 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.3 GO:0097452 GAIT complex(GO:0097452)
0.0 0.9 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.3 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.0 GO:0035101 FACT complex(GO:0035101)
0.0 0.5 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.1 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.4 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.3 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.1 GO:0035838 growing cell tip(GO:0035838)
0.0 0.4 GO:0043219 lateral loop(GO:0043219)
0.0 0.2 GO:0001740 Barr body(GO:0001740)
0.0 0.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.2 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.2 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.5 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 1.6 GO:0016235 aggresome(GO:0016235)
0.0 0.2 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.3 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.2 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.0 GO:0019034 viral replication complex(GO:0019034)
0.0 0.3 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 0.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.1 GO:0033176 proton-transporting V-type ATPase complex(GO:0033176)
0.0 0.3 GO:0042555 MCM complex(GO:0042555)
0.0 0.1 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 0.0 GO:0005595 collagen type XII trimer(GO:0005595)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.1 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.9 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.1 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.0 0.0 GO:0008043 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0 0.4 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 0.2 GO:0000782 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 0.2 GO:0030914 STAGA complex(GO:0030914)
0.0 1.5 GO:0005901 caveola(GO:0005901)
0.0 0.1 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 0.3 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.1 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.2 0.9 GO:0004348 glucosylceramidase activity(GO:0004348)
0.2 0.5 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.1 0.4 GO:0070361 mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.1 0.9 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.1 0.6 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1 0.4 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.1 0.3 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.1 0.8 GO:0016936 galactoside binding(GO:0016936)
0.1 1.0 GO:0019826 oxygen sensor activity(GO:0019826)
0.1 0.3 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.1 0.4 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 0.4 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 0.2 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 0.3 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 2.9 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 0.3 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.1 0.2 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.1 0.7 GO:0051434 BH3 domain binding(GO:0051434)
0.1 0.2 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1 0.2 GO:0030984 kininogen binding(GO:0030984)
0.1 0.6 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.1 0.2 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1 0.3 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.3 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1 0.3 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1 0.2 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.1 0.3 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.4 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.5 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0 0.2 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.1 GO:0008841 tetrahydrofolylpolyglutamate synthase activity(GO:0004326) dihydrofolate synthase activity(GO:0008841)
0.0 1.0 GO:0015929 hexosaminidase activity(GO:0015929)
0.0 0.2 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.2 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.0 0.2 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 1.7 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.8 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.2 GO:0019770 IgG receptor activity(GO:0019770)
0.0 0.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.1 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.0 0.1 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 0.1 GO:0035240 dopamine binding(GO:0035240)
0.0 0.3 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.1 GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0 0.1 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.0 0.1 GO:0015633 zinc transporting ATPase activity(GO:0015633)
0.0 0.0 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 1.0 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.2 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.2 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.2 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.3 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.1 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.0 0.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.2 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.1 GO:0015207 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.0 0.3 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.1 GO:0008892 guanine deaminase activity(GO:0008892)
0.0 0.7 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.2 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.2 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 0.0 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.0 0.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.1 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0 0.1 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.2 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.2 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.1 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.1 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) aspartic-type endopeptidase inhibitor activity(GO:0019828) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.1 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.1 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.1 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.0 0.1 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.1 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.0 GO:0008047 enzyme activator activity(GO:0008047)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.6 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.1 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.1 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.1 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.2 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.1 GO:0004306 ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.0 0.1 GO:0019144 ADP-sugar diphosphatase activity(GO:0019144) adenosine-diphosphatase activity(GO:0043262)
0.0 0.3 GO:0010181 FMN binding(GO:0010181)
0.0 0.9 GO:0050699 WW domain binding(GO:0050699)
0.0 1.5 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.3 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.1 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.3 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.1 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.3 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.0 GO:0016898 D-lactate dehydrogenase (cytochrome) activity(GO:0004458) oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor(GO:0016898)
0.0 0.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.1 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.1 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.0 GO:0001602 peptide YY receptor activity(GO:0001601) pancreatic polypeptide receptor activity(GO:0001602)
0.0 0.1 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.7 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.7 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.6 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.0 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.1 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 2.2 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 1.4 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 1.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 2.3 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.8 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.8 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.6 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.3 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.5 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.4 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.5 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.4 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.7 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.2 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.9 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.6 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 1.2 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.3 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.3 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation