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avrg: A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for SOX30

Z-value: 1.47

Motif logo

Transcription factors associated with SOX30

Gene Symbol Gene ID Gene Info
ENSG00000039600.6 SOX30

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX30hg19_v2_chr5_-_157079372_157079395-0.604.0e-01Click!

Activity profile of SOX30 motif

Sorted Z-values of SOX30 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX30

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr7_+_100770328 1.40 ENST00000223095.4
ENST00000445463.2
SERPINE1
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
chr3_-_122283424 0.84 ENST00000477522.2
ENST00000360356.2
PARP9
poly (ADP-ribose) polymerase family, member 9
chr22_-_30970498 0.82 ENST00000431313.1
GAL3ST1
galactose-3-O-sulfotransferase 1
chr22_+_31488433 0.82 ENST00000455608.1
SMTN
smoothelin
chr5_-_146461027 0.79 ENST00000394410.2
ENST00000508267.1
ENST00000504198.1
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr14_+_101299520 0.64 ENST00000455531.1
MEG3
maternally expressed 3 (non-protein coding)
chr4_+_54243798 0.61 ENST00000337488.6
ENST00000358575.5
ENST00000507922.1
FIP1L1
factor interacting with PAPOLA and CPSF1
chr2_-_158182322 0.60 ENST00000420719.2
ENST00000409216.1
ERMN
ermin, ERM-like protein
chr12_-_10588539 0.59 ENST00000381902.2
ENST00000381901.1
ENST00000539033.1
KLRC2
NKG2-E
killer cell lectin-like receptor subfamily C, member 2
Uncharacterized protein
chr22_-_30970560 0.59 ENST00000402369.1
ENST00000406361.1
GAL3ST1
galactose-3-O-sulfotransferase 1
chr1_+_149239529 0.55 ENST00000457216.2
RP11-403I13.4
RP11-403I13.4
chr17_+_67498295 0.52 ENST00000589295.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr2_+_232573208 0.52 ENST00000409115.3
PTMA
prothymosin, alpha
chr6_-_134639180 0.51 ENST00000367858.5
SGK1
serum/glucocorticoid regulated kinase 1
chr1_-_201476274 0.50 ENST00000340006.2
CSRP1
cysteine and glycine-rich protein 1
chr20_-_5426380 0.50 ENST00000609252.1
ENST00000422352.1
LINC00658
long intergenic non-protein coding RNA 658
chr4_-_176733897 0.49 ENST00000393658.2
GPM6A
glycoprotein M6A
chr12_+_93096619 0.49 ENST00000397833.3
C12orf74
chromosome 12 open reading frame 74
chr14_-_36645674 0.48 ENST00000556013.2
PTCSC3
papillary thyroid carcinoma susceptibility candidate 3 (non-protein coding)
chr12_+_9066472 0.47 ENST00000538657.1
PHC1
polyhomeotic homolog 1 (Drosophila)
chr12_+_93096759 0.46 ENST00000544406.2
C12orf74
chromosome 12 open reading frame 74
chr9_-_134145880 0.46 ENST00000372269.3
ENST00000464831.1
FAM78A
family with sequence similarity 78, member A
chr11_+_46402744 0.46 ENST00000533952.1
MDK
midkine (neurite growth-promoting factor 2)
chr22_+_46449674 0.43 ENST00000381051.2
FLJ27365
hsa-mir-4763
chr2_+_143635067 0.40 ENST00000264170.4
KYNU
kynureninase
chr4_+_54243862 0.39 ENST00000306932.6
FIP1L1
factor interacting with PAPOLA and CPSF1
chr5_+_179135246 0.38 ENST00000508787.1
CANX
calnexin
chr2_+_232573222 0.36 ENST00000341369.7
ENST00000409683.1
PTMA
prothymosin, alpha
chr18_+_68002675 0.35 ENST00000584919.1
RP11-41O4.1
Uncharacterized protein
chr12_+_27623565 0.34 ENST00000535986.1
SMCO2
single-pass membrane protein with coiled-coil domains 2
chr15_+_76629064 0.34 ENST00000290759.4
ISL2
ISL LIM homeobox 2
chr6_-_161085291 0.32 ENST00000316300.5
LPA
lipoprotein, Lp(a)
chr1_+_244998602 0.31 ENST00000411948.2
COX20
COX20 cytochrome C oxidase assembly factor
chr11_-_89224638 0.30 ENST00000535633.1
ENST00000263317.4
NOX4
NADPH oxidase 4
chr1_-_21503337 0.30 ENST00000400422.1
ENST00000602326.1
ENST00000411888.1
ENST00000438975.1
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr7_+_870547 0.28 ENST00000457598.1
SUN1
Sad1 and UNC84 domain containing 1
chr12_+_95611536 0.28 ENST00000549002.1
VEZT
vezatin, adherens junctions transmembrane protein
chr2_+_99953816 0.28 ENST00000289371.6
EIF5B
eukaryotic translation initiation factor 5B
chr3_+_19988736 0.27 ENST00000443878.1
RAB5A
RAB5A, member RAS oncogene family
chr2_+_179184955 0.27 ENST00000315022.2
OSBPL6
oxysterol binding protein-like 6
chr1_+_244998918 0.26 ENST00000366528.3
COX20
COX20 cytochrome C oxidase assembly factor
chr10_+_35484793 0.26 ENST00000488741.1
ENST00000474931.1
ENST00000468236.1
ENST00000344351.5
ENST00000490511.1
CREM
cAMP responsive element modulator
chr12_+_11905413 0.25 ENST00000545027.1
ETV6
ets variant 6
chr22_-_43485381 0.25 ENST00000331018.7
ENST00000266254.7
ENST00000445824.1
TTLL1
tubulin tyrosine ligase-like family, member 1
chr4_+_113152978 0.25 ENST00000309703.6
AP1AR
adaptor-related protein complex 1 associated regulatory protein
chr6_+_131958436 0.24 ENST00000357639.3
ENST00000543135.1
ENST00000427148.2
ENST00000358229.5
ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr14_+_52456193 0.23 ENST00000261700.3
C14orf166
chromosome 14 open reading frame 166
chr6_-_49712123 0.23 ENST00000263045.4
CRISP3
cysteine-rich secretory protein 3
chr5_+_140593509 0.23 ENST00000341948.4
PCDHB13
protocadherin beta 13
chr12_-_99288986 0.22 ENST00000552407.1
ENST00000551613.1
ENST00000548447.1
ENST00000546364.3
ENST00000552748.1
ANKS1B
ankyrin repeat and sterile alpha motif domain containing 1B
chr1_+_180897269 0.22 ENST00000367587.1
KIAA1614
KIAA1614
chr2_-_158182410 0.22 ENST00000419116.2
ENST00000410096.1
ERMN
ermin, ERM-like protein
chrX_+_102192200 0.20 ENST00000218249.5
RAB40AL
RAB40A, member RAS oncogene family-like
chr6_+_126240442 0.20 ENST00000448104.1
ENST00000438495.1
ENST00000444128.1
NCOA7
nuclear receptor coactivator 7
chr3_+_140981456 0.19 ENST00000504264.1
ACPL2
acid phosphatase-like 2
chr4_+_54243917 0.19 ENST00000507166.1
FIP1L1
factor interacting with PAPOLA and CPSF1
chr12_-_11036844 0.18 ENST00000428168.2
PRH1
proline-rich protein HaeIII subfamily 1
chr1_+_40942887 0.17 ENST00000372706.1
ZFP69
ZFP69 zinc finger protein
chr11_+_63137251 0.17 ENST00000310969.4
ENST00000279178.3
SLC22A9
solute carrier family 22 (organic anion transporter), member 9
chrX_-_24690771 0.17 ENST00000379145.1
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr16_+_20499024 0.17 ENST00000593357.1
AC137056.1
Uncharacterized protein; cDNA FLJ34659 fis, clone KIDNE2018863
chr8_+_42195972 0.16 ENST00000532157.1
ENST00000265421.4
ENST00000520008.1
POLB
polymerase (DNA directed), beta
chr7_-_122840015 0.16 ENST00000194130.2
SLC13A1
solute carrier family 13 (sodium/sulfate symporter), member 1
chr12_-_10251539 0.16 ENST00000420265.2
CLEC1A
C-type lectin domain family 1, member A
chr8_+_24151620 0.16 ENST00000437154.2
ADAM28
ADAM metallopeptidase domain 28
chr2_-_166060571 0.15 ENST00000360093.3
SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr7_-_82792215 0.15 ENST00000333891.9
ENST00000423517.2
PCLO
piccolo presynaptic cytomatrix protein
chr4_-_69111401 0.15 ENST00000332644.5
TMPRSS11B
transmembrane protease, serine 11B
chr12_+_50898881 0.15 ENST00000301180.5
DIP2B
DIP2 disco-interacting protein 2 homolog B (Drosophila)
chr10_+_35416090 0.15 ENST00000354759.3
CREM
cAMP responsive element modulator
chr1_-_85930246 0.15 ENST00000426972.3
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr12_-_10251603 0.14 ENST00000457018.2
CLEC1A
C-type lectin domain family 1, member A
chr1_+_74701062 0.14 ENST00000326637.3
TNNI3K
TNNI3 interacting kinase
chr12_+_95611516 0.13 ENST00000436874.1
VEZT
vezatin, adherens junctions transmembrane protein
chr11_+_128563652 0.13 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr12_-_10251576 0.13 ENST00000315330.4
CLEC1A
C-type lectin domain family 1, member A
chr1_-_156828810 0.13 ENST00000368195.3
INSRR
insulin receptor-related receptor
chr1_+_47489240 0.13 ENST00000371901.3
CYP4X1
cytochrome P450, family 4, subfamily X, polypeptide 1
chr12_-_10282836 0.12 ENST00000304084.8
ENST00000353231.5
ENST00000525605.1
CLEC7A
C-type lectin domain family 7, member A
chr21_+_30671690 0.12 ENST00000399921.1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr20_-_45981138 0.12 ENST00000446994.2
ZMYND8
zinc finger, MYND-type containing 8
chr12_+_95611569 0.12 ENST00000261219.6
ENST00000551472.1
ENST00000552821.1
VEZT
vezatin, adherens junctions transmembrane protein
chr19_-_17375541 0.12 ENST00000252597.3
USHBP1
Usher syndrome 1C binding protein 1
chr3_-_18466026 0.11 ENST00000417717.2
SATB1
SATB homeobox 1
chr2_-_162931052 0.11 ENST00000360534.3
DPP4
dipeptidyl-peptidase 4
chr1_+_185014496 0.11 ENST00000367510.3
RNF2
ring finger protein 2
chr1_-_167883353 0.10 ENST00000545172.1
ADCY10
adenylate cyclase 10 (soluble)
chr1_-_201476220 0.10 ENST00000526723.1
ENST00000524951.1
CSRP1
cysteine and glycine-rich protein 1
chr4_-_40516560 0.10 ENST00000513473.1
RBM47
RNA binding motif protein 47
chr1_-_243418650 0.09 ENST00000522995.1
CEP170
centrosomal protein 170kDa
chr3_-_57583130 0.09 ENST00000303436.6
ARF4
ADP-ribosylation factor 4
chr1_-_119532127 0.09 ENST00000207157.3
TBX15
T-box 15
chr3_-_19988462 0.08 ENST00000344838.4
EFHB
EF-hand domain family, member B
chr1_+_185703513 0.08 ENST00000271588.4
ENST00000367492.2
HMCN1
hemicentin 1
chr11_+_36317830 0.08 ENST00000530639.1
PRR5L
proline rich 5 like
chr17_+_67498538 0.08 ENST00000589647.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr11_+_128563948 0.08 ENST00000534087.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr11_-_18548426 0.08 ENST00000357193.3
ENST00000536719.1
TSG101
tumor susceptibility 101
chr2_-_166060382 0.07 ENST00000409101.3
SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr10_-_28270795 0.07 ENST00000545014.1
ARMC4
armadillo repeat containing 4
chr9_-_74383302 0.07 ENST00000377066.5
TMEM2
transmembrane protein 2
chr1_+_240255166 0.07 ENST00000319653.9
FMN2
formin 2
chr5_+_66254698 0.07 ENST00000405643.1
ENST00000407621.1
ENST00000432426.1
MAST4
microtubule associated serine/threonine kinase family member 4
chrX_+_41192595 0.07 ENST00000399959.2
DDX3X
DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
chr5_+_140235469 0.07 ENST00000506939.2
ENST00000307360.5
PCDHA10
protocadherin alpha 10
chr6_-_11779174 0.07 ENST00000379413.2
ADTRP
androgen-dependent TFPI-regulating protein
chr7_-_107443652 0.06 ENST00000340010.5
ENST00000422236.2
ENST00000453332.1
SLC26A3
solute carrier family 26 (anion exchanger), member 3
chr12_-_10282742 0.06 ENST00000298523.5
ENST00000396484.2
ENST00000310002.4
CLEC7A
C-type lectin domain family 7, member A
chr11_-_85430356 0.06 ENST00000526999.1
SYTL2
synaptotagmin-like 2
chr4_+_71457970 0.05 ENST00000322937.6
AMBN
ameloblastin (enamel matrix protein)
chr2_+_223536428 0.05 ENST00000446656.3
MOGAT1
monoacylglycerol O-acyltransferase 1
chr11_-_8964580 0.05 ENST00000325884.1
ASCL3
achaete-scute family bHLH transcription factor 3
chr5_+_170288856 0.04 ENST00000523189.1
RANBP17
RAN binding protein 17
chr4_+_71458012 0.04 ENST00000449493.2
AMBN
ameloblastin (enamel matrix protein)
chrY_+_15016013 0.04 ENST00000360160.4
ENST00000454054.1
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr10_+_35415851 0.04 ENST00000374726.3
CREM
cAMP responsive element modulator
chr6_-_11779014 0.03 ENST00000229583.5
ADTRP
androgen-dependent TFPI-regulating protein
chr18_+_7946839 0.03 ENST00000578916.1
PTPRM
protein tyrosine phosphatase, receptor type, M
chr2_-_37899323 0.03 ENST00000295324.3
ENST00000457889.1
CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr4_-_70725856 0.03 ENST00000226444.3
SULT1E1
sulfotransferase family 1E, estrogen-preferring, member 1
chr5_+_38148582 0.02 ENST00000508853.1
CTD-2207A17.1
CTD-2207A17.1
chr4_-_87028478 0.02 ENST00000515400.1
ENST00000395157.3
MAPK10
mitogen-activated protein kinase 10
chr4_+_144303093 0.02 ENST00000505913.1
GAB1
GRB2-associated binding protein 1
chr9_-_85882145 0.02 ENST00000328788.1
FRMD3
FERM domain containing 3
chr1_-_243418621 0.01 ENST00000366544.1
ENST00000366543.1
CEP170
centrosomal protein 170kDa
chr3_+_19988566 0.01 ENST00000273047.4
RAB5A
RAB5A, member RAS oncogene family
chr14_+_52456327 0.01 ENST00000556760.1
C14orf166
chromosome 14 open reading frame 166
chr19_-_17375527 0.01 ENST00000431146.2
ENST00000594190.1
USHBP1
Usher syndrome 1C binding protein 1
chr1_+_228337553 0.00 ENST00000366714.2
GJC2
gap junction protein, gamma 2, 47kDa

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0001300 chronological cell aging(GO:0001300)
0.1 1.4 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 0.5 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 0.4 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.1 0.3 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.1 0.2 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.1 0.2 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 0.8 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 0.5 GO:0030421 defecation(GO:0030421)
0.1 1.2 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 0.2 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.0 0.5 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.8 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.1 GO:0071469 cellular response to alkaline pH(GO:0071469)
0.0 0.3 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.3 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.1 GO:0036343 psychomotor behavior(GO:0036343)
0.0 0.6 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.3 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.1 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.0 0.3 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.1 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.0 0.3 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.0 0.1 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.1 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952)
0.0 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.4 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.2 GO:0015747 urate transport(GO:0015747)
0.0 0.2 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0 0.2 GO:1902358 sulfate transmembrane transport(GO:1902358)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0033269 internode region of axon(GO:0033269)
0.0 1.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.6 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.3 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 0.4 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.5 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.3 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 1.4 GO:0031093 platelet alpha granule lumen(GO:0031093)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.1 1.4 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 0.4 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.1 0.2 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.1 0.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.2 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.3 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.8 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.3 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.7 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.1 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.1 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.5 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.2 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.5 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.1 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.2 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 1.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.5 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.8 PID ATR PATHWAY ATR signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 1.4 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.4 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.5 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation