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avrg: A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for KLF1

Z-value: 0.97

Motif logo

Transcription factors associated with KLF1

Gene Symbol Gene ID Gene Info
ENSG00000105610.4 KLF1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
KLF1hg19_v2_chr19_-_12997995_129980210.693.1e-01Click!

Activity profile of KLF1 motif

Sorted Z-values of KLF1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr14_+_32414059 1.23 ENST00000553330.1
RP11-187E13.1
Uncharacterized protein
chr20_-_52687059 0.75 ENST00000371435.2
ENST00000395961.3
BCAS1
breast carcinoma amplified sequence 1
chr16_-_67427389 0.62 ENST00000562206.1
ENST00000290942.5
ENST00000393957.2
TPPP3
tubulin polymerization-promoting protein family member 3
chr3_+_186330712 0.56 ENST00000411641.2
ENST00000273784.5
AHSG
alpha-2-HS-glycoprotein
chr5_+_162864575 0.53 ENST00000512163.1
ENST00000393929.1
ENST00000340828.2
ENST00000511683.2
ENST00000510097.1
ENST00000511490.2
ENST00000510664.1
CCNG1
cyclin G1
chr1_-_33168336 0.50 ENST00000373484.3
SYNC
syncoilin, intermediate filament protein
chr16_-_31161380 0.49 ENST00000569305.1
ENST00000418068.2
ENST00000268281.4
PRSS36
protease, serine, 36
chr22_-_20138302 0.48 ENST00000540078.1
ENST00000439765.2
AC006547.14
uncharacterized protein LOC388849
chr8_-_101963482 0.45 ENST00000419477.2
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr1_+_6845578 0.45 ENST00000467404.2
ENST00000439411.2
CAMTA1
calmodulin binding transcription activator 1
chr7_-_91875109 0.43 ENST00000412043.2
ENST00000430102.1
ENST00000425073.1
ENST00000394503.2
ENST00000454017.1
ENST00000440209.1
ENST00000413688.1
ENST00000452773.1
ENST00000433016.1
ENST00000394505.2
ENST00000422347.1
ENST00000458493.1
ENST00000425919.1
KRIT1
KRIT1, ankyrin repeat containing
chr8_+_120428546 0.42 ENST00000259526.3
NOV
nephroblastoma overexpressed
chrX_+_47077680 0.42 ENST00000522883.1
CDK16
cyclin-dependent kinase 16
chr2_-_38604398 0.40 ENST00000443098.1
ENST00000449130.1
ENST00000378954.4
ENST00000539122.1
ENST00000419554.2
ENST00000451483.1
ENST00000406122.1
ATL2
atlastin GTPase 2
chr6_+_43968306 0.40 ENST00000442114.2
ENST00000336600.5
ENST00000439969.2
C6orf223
chromosome 6 open reading frame 223
chr5_+_95998673 0.38 ENST00000514845.1
CAST
calpastatin
chr9_-_33264676 0.38 ENST00000472232.3
ENST00000379704.2
BAG1
BCL2-associated athanogene
chr9_-_33264557 0.37 ENST00000473781.1
ENST00000488499.1
BAG1
BCL2-associated athanogene
chr2_+_206950095 0.37 ENST00000435627.1
AC007383.3
AC007383.3
chr18_-_48723690 0.36 ENST00000406189.3
MEX3C
mex-3 RNA binding family member C
chr11_+_62475130 0.35 ENST00000294117.5
GNG3
guanine nucleotide binding protein (G protein), gamma 3
chr20_-_62710832 0.35 ENST00000395042.1
RGS19
regulator of G-protein signaling 19
chr14_+_59951161 0.34 ENST00000261247.9
ENST00000425728.2
ENST00000556985.1
ENST00000554271.1
ENST00000554795.1
JKAMP
JNK1/MAPK8-associated membrane protein
chr17_-_7080227 0.33 ENST00000574330.1
ASGR1
asialoglycoprotein receptor 1
chr8_-_143867946 0.33 ENST00000301263.4
LY6D
lymphocyte antigen 6 complex, locus D
chr8_+_38614754 0.31 ENST00000521642.1
TACC1
transforming, acidic coiled-coil containing protein 1
chr1_-_244615425 0.31 ENST00000366535.3
ADSS
adenylosuccinate synthase
chr12_-_57443886 0.31 ENST00000300119.3
MYO1A
myosin IA
chr19_+_38880695 0.30 ENST00000587947.1
ENST00000338502.4
SPRED3
sprouty-related, EVH1 domain containing 3
chr9_+_74764340 0.30 ENST00000376986.1
ENST00000358399.3
GDA
guanine deaminase
chr1_-_185286461 0.30 ENST00000367498.3
IVNS1ABP
influenza virus NS1A binding protein
chr5_+_95998714 0.29 ENST00000506811.1
ENST00000514055.1
CAST
calpastatin
chr6_-_138428613 0.29 ENST00000421351.3
PERP
PERP, TP53 apoptosis effector
chr17_+_40950797 0.29 ENST00000588408.1
ENST00000585355.1
CNTD1
cyclin N-terminal domain containing 1
chr2_-_55237484 0.29 ENST00000394609.2
RTN4
reticulon 4
chr17_+_46131912 0.28 ENST00000584634.1
ENST00000580050.1
NFE2L1
nuclear factor, erythroid 2-like 1
chr12_+_56477093 0.28 ENST00000549672.1
ENST00000415288.2
ERBB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr19_+_7599792 0.27 ENST00000600942.1
ENST00000593924.1
PNPLA6
patatin-like phospholipase domain containing 6
chr7_+_35840819 0.27 ENST00000399035.3
SEPT7
septin 7
chr2_+_67624430 0.27 ENST00000272342.5
ETAA1
Ewing tumor-associated antigen 1
chr19_-_40440533 0.26 ENST00000221347.6
FCGBP
Fc fragment of IgG binding protein
chr6_-_82462425 0.26 ENST00000369754.3
ENST00000320172.6
ENST00000369756.3
FAM46A
family with sequence similarity 46, member A
chr3_-_113464906 0.26 ENST00000477813.1
NAA50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr17_+_46131843 0.26 ENST00000577411.1
NFE2L1
nuclear factor, erythroid 2-like 1
chr15_+_76352178 0.25 ENST00000388942.3
C15orf27
chromosome 15 open reading frame 27
chr17_-_27405875 0.25 ENST00000359450.6
TIAF1
TGFB1-induced anti-apoptotic factor 1
chr5_+_110074685 0.25 ENST00000355943.3
ENST00000447245.2
SLC25A46
solute carrier family 25, member 46
chr5_-_89770582 0.25 ENST00000316610.6
MBLAC2
metallo-beta-lactamase domain containing 2
chr19_+_1077393 0.25 ENST00000590577.1
HMHA1
histocompatibility (minor) HA-1
chr15_+_90931450 0.25 ENST00000268182.5
ENST00000560738.1
ENST00000560418.1
IQGAP1
IQ motif containing GTPase activating protein 1
chr8_-_21988558 0.25 ENST00000312841.8
HR
hair growth associated
chr5_+_82767583 0.25 ENST00000512590.2
ENST00000513960.1
ENST00000513984.1
ENST00000502527.2
VCAN
versican
chr7_-_91875358 0.24 ENST00000458177.1
ENST00000394507.1
ENST00000340022.2
ENST00000444960.1
KRIT1
KRIT1, ankyrin repeat containing
chr19_-_51523275 0.24 ENST00000309958.3
KLK10
kallikrein-related peptidase 10
chr4_-_103748271 0.24 ENST00000343106.5
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr1_-_59165763 0.24 ENST00000472487.1
MYSM1
Myb-like, SWIRM and MPN domains 1
chr19_+_18451439 0.24 ENST00000597431.2
PGPEP1
pyroglutamyl-peptidase I
chr14_+_21569245 0.24 ENST00000556585.2
TMEM253
transmembrane protein 253
chr5_+_95998070 0.24 ENST00000421689.2
ENST00000510756.1
ENST00000512620.1
CAST
calpastatin
chr1_+_62901968 0.23 ENST00000452143.1
ENST00000442679.1
ENST00000371146.1
USP1
ubiquitin specific peptidase 1
chr6_-_84140757 0.23 ENST00000541327.1
ENST00000369705.3
ENST00000543031.1
ME1
malic enzyme 1, NADP(+)-dependent, cytosolic
chr3_-_101395936 0.23 ENST00000461821.1
ZBTB11
zinc finger and BTB domain containing 11
chr20_-_52687030 0.23 ENST00000411563.1
BCAS1
breast carcinoma amplified sequence 1
chr10_+_17272608 0.23 ENST00000421459.2
VIM
vimentin
chr5_+_95998746 0.23 ENST00000508608.1
CAST
calpastatin
chr6_+_42952237 0.23 ENST00000485511.1
ENST00000394110.3
ENST00000472118.1
ENST00000461010.1
PPP2R5D
protein phosphatase 2, regulatory subunit B', delta
chr2_+_173292301 0.23 ENST00000264106.6
ENST00000375221.2
ENST00000343713.4
ITGA6
integrin, alpha 6
chr3_-_50383096 0.22 ENST00000442887.1
ENST00000360165.3
ZMYND10
zinc finger, MYND-type containing 10
chr5_+_133562095 0.22 ENST00000602919.1
CTD-2410N18.3
CTD-2410N18.3
chr1_+_222885884 0.22 ENST00000340934.5
BROX
BRO1 domain and CAAX motif containing
chr10_+_98592009 0.22 ENST00000540664.1
ENST00000371103.3
LCOR
ligand dependent nuclear receptor corepressor
chr12_+_69004805 0.22 ENST00000541216.1
RAP1B
RAP1B, member of RAS oncogene family
chr12_+_100661156 0.22 ENST00000360820.2
SCYL2
SCY1-like 2 (S. cerevisiae)
chr7_+_17338239 0.21 ENST00000242057.4
AHR
aryl hydrocarbon receptor
chr11_-_71781096 0.21 ENST00000535087.1
ENST00000535838.1
NUMA1
nuclear mitotic apparatus protein 1
chr6_+_74405804 0.21 ENST00000287097.5
CD109
CD109 molecule
chr17_+_34900737 0.21 ENST00000304718.4
ENST00000485685.2
GGNBP2
gametogenetin binding protein 2
chr6_+_74405501 0.21 ENST00000437994.2
ENST00000422508.2
CD109
CD109 molecule
chr4_+_178230985 0.21 ENST00000264596.3
NEIL3
nei endonuclease VIII-like 3 (E. coli)
chr3_+_181429704 0.20 ENST00000431565.2
ENST00000325404.1
SOX2
SRY (sex determining region Y)-box 2
chr1_-_98510843 0.20 ENST00000413670.2
ENST00000538428.1
MIR137HG
MIR137 host gene (non-protein coding)
chr3_-_88108192 0.20 ENST00000309534.6
CGGBP1
CGG triplet repeat binding protein 1
chr7_-_102158157 0.20 ENST00000541662.1
ENST00000306682.6
ENST00000465829.1
RASA4B
RAS p21 protein activator 4B
chr5_+_102595119 0.20 ENST00000510890.1
C5orf30
chromosome 5 open reading frame 30
chr20_-_62168672 0.20 ENST00000217185.2
PTK6
protein tyrosine kinase 6
chr12_+_116997186 0.20 ENST00000306985.4
MAP1LC3B2
microtubule-associated protein 1 light chain 3 beta 2
chr6_+_142623063 0.20 ENST00000296932.8
ENST00000367609.3
GPR126
G protein-coupled receptor 126
chr1_+_6845497 0.20 ENST00000473578.1
ENST00000557126.1
CAMTA1
calmodulin binding transcription activator 1
chr1_+_29213584 0.19 ENST00000343067.4
ENST00000356093.2
ENST00000398863.2
ENST00000373800.3
ENST00000349460.4
EPB41
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr19_-_51523412 0.19 ENST00000391805.1
ENST00000599077.1
KLK10
kallikrein-related peptidase 10
chr16_-_30125177 0.19 ENST00000406256.3
GDPD3
glycerophosphodiester phosphodiesterase domain containing 3
chr19_-_36297348 0.19 ENST00000589835.1
PRODH2
proline dehydrogenase (oxidase) 2
chr4_+_129730947 0.19 ENST00000452328.2
ENST00000504089.1
PHF17
jade family PHD finger 1
chr10_+_94608245 0.19 ENST00000443748.2
ENST00000260762.6
EXOC6
exocyst complex component 6
chr1_+_224803995 0.19 ENST00000272133.3
CNIH3
cornichon family AMPA receptor auxiliary protein 3
chr8_+_38758737 0.19 ENST00000521746.1
ENST00000420274.1
PLEKHA2
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
chr8_-_101963677 0.19 ENST00000395956.3
ENST00000395953.2
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr1_+_97187318 0.19 ENST00000609116.1
ENST00000370198.1
ENST00000370197.1
ENST00000426398.2
ENST00000394184.3
PTBP2
polypyrimidine tract binding protein 2
chr1_+_62902308 0.19 ENST00000339950.4
USP1
ubiquitin specific peptidase 1
chr1_-_205744205 0.18 ENST00000446390.2
RAB7L1
RAB7, member RAS oncogene family-like 1
chr14_-_59950724 0.18 ENST00000481608.1
L3HYPDH
L-3-hydroxyproline dehydratase (trans-)
chr2_+_28974603 0.18 ENST00000441461.1
ENST00000358506.2
PPP1CB
protein phosphatase 1, catalytic subunit, beta isozyme
chr8_+_38758845 0.18 ENST00000519640.1
PLEKHA2
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
chr13_+_88324870 0.18 ENST00000325089.6
SLITRK5
SLIT and NTRK-like family, member 5
chr2_-_148779106 0.18 ENST00000416719.1
ENST00000264169.2
ORC4
origin recognition complex, subunit 4
chr6_-_30710265 0.18 ENST00000438162.1
ENST00000454845.1
FLOT1
flotillin 1
chr1_-_115259337 0.18 ENST00000369535.4
NRAS
neuroblastoma RAS viral (v-ras) oncogene homolog
chr3_+_106959530 0.18 ENST00000466734.1
ENST00000463143.1
ENST00000490441.1
LINC00883
long intergenic non-protein coding RNA 883
chr1_+_111682827 0.18 ENST00000357172.4
CEPT1
choline/ethanolamine phosphotransferase 1
chr14_-_65409438 0.18 ENST00000557049.1
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr1_-_166135952 0.18 ENST00000354422.3
FAM78B
family with sequence similarity 78, member B
chr19_-_36523529 0.18 ENST00000593074.1
CLIP3
CAP-GLY domain containing linker protein 3
chr20_+_43029911 0.18 ENST00000443598.2
ENST00000316099.4
ENST00000415691.2
HNF4A
hepatocyte nuclear factor 4, alpha
chr5_-_37249397 0.18 ENST00000425232.2
ENST00000274258.7
C5orf42
chromosome 5 open reading frame 42
chr1_-_39395165 0.18 ENST00000372985.3
RHBDL2
rhomboid, veinlet-like 2 (Drosophila)
chr15_-_64648273 0.17 ENST00000607537.1
ENST00000303052.7
ENST00000303032.6
CSNK1G1
casein kinase 1, gamma 1
chr7_-_102257139 0.17 ENST00000521076.1
ENST00000462172.1
ENST00000522801.1
ENST00000449970.2
ENST00000262940.7
RASA4
RAS p21 protein activator 4
chr6_+_142622991 0.17 ENST00000230173.6
ENST00000367608.2
GPR126
G protein-coupled receptor 126
chr16_+_30675654 0.17 ENST00000287468.5
ENST00000395073.2
FBRS
fibrosin
chr14_-_65409502 0.17 ENST00000389614.5
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr3_-_186080012 0.17 ENST00000544847.1
ENST00000265022.3
DGKG
diacylglycerol kinase, gamma 90kDa
chr3_-_182817297 0.17 ENST00000539926.1
ENST00000476176.1
MCCC1
methylcrotonoyl-CoA carboxylase 1 (alpha)
chr1_+_154966058 0.17 ENST00000392487.1
LENEP
lens epithelial protein
chr20_+_47662805 0.17 ENST00000262982.2
ENST00000542325.1
CSE1L
CSE1 chromosome segregation 1-like (yeast)
chr9_+_139746792 0.17 ENST00000317446.2
ENST00000445819.1
MAMDC4
MAM domain containing 4
chr12_-_110939870 0.17 ENST00000447578.2
ENST00000546588.1
ENST00000360579.7
ENST00000549970.1
ENST00000549578.1
VPS29
vacuolar protein sorting 29 homolog (S. cerevisiae)
chr3_+_106959552 0.16 ENST00000473550.1
LINC00883
long intergenic non-protein coding RNA 883
chr1_+_173837488 0.16 ENST00000427304.1
ENST00000432989.1
ENST00000367702.1
ZBTB37
zinc finger and BTB domain containing 37
chr1_+_17914907 0.16 ENST00000375420.3
ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr1_+_203765437 0.16 ENST00000550078.1
ZBED6
zinc finger, BED-type containing 6
chr17_-_7166500 0.16 ENST00000575313.1
ENST00000397317.4
CLDN7
claudin 7
chr11_-_1606513 0.16 ENST00000382171.2
KRTAP5-1
keratin associated protein 5-1
chr16_+_46723552 0.16 ENST00000219097.2
ENST00000568364.2
ORC6
origin recognition complex, subunit 6
chr19_-_44008863 0.16 ENST00000601646.1
PHLDB3
pleckstrin homology-like domain, family B, member 3
chr16_+_28996114 0.16 ENST00000395461.3
LAT
linker for activation of T cells
chr14_+_96342729 0.16 ENST00000504119.1
LINC00617
long intergenic non-protein coding RNA 617
chr11_-_34937858 0.16 ENST00000278359.5
APIP
APAF1 interacting protein
chr2_-_55276320 0.16 ENST00000357376.3
RTN4
reticulon 4
chr9_+_110046334 0.16 ENST00000416373.2
RAD23B
RAD23 homolog B (S. cerevisiae)
chr17_-_74023474 0.16 ENST00000301607.3
EVPL
envoplakin
chr5_-_137368708 0.15 ENST00000033079.3
FAM13B
family with sequence similarity 13, member B
chr1_-_205744574 0.15 ENST00000367139.3
ENST00000235932.4
ENST00000437324.2
ENST00000414729.1
RAB7L1
RAB7, member RAS oncogene family-like 1
chr17_-_27188984 0.15 ENST00000582320.2
MIR144
microRNA 451b
chr1_+_67390578 0.15 ENST00000371018.3
ENST00000355977.6
ENST00000357692.2
ENST00000401041.1
ENST00000371016.1
ENST00000371014.1
ENST00000371012.2
MIER1
mesoderm induction early response 1, transcriptional regulator
chr13_-_45010939 0.15 ENST00000261489.2
TSC22D1
TSC22 domain family, member 1
chr2_+_28974531 0.15 ENST00000420282.1
PPP1CB
protein phosphatase 1, catalytic subunit, beta isozyme
chr3_+_49449636 0.15 ENST00000273590.3
TCTA
T-cell leukemia translocation altered
chr12_-_80328949 0.14 ENST00000450142.2
PPP1R12A
protein phosphatase 1, regulatory subunit 12A
chr8_-_103136481 0.14 ENST00000524209.1
ENST00000517822.1
ENST00000523923.1
ENST00000521599.1
ENST00000521964.1
ENST00000311028.3
ENST00000518166.1
NCALD
neurocalcin delta
chr2_-_153574480 0.14 ENST00000410080.1
PRPF40A
PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
chr2_+_74212073 0.14 ENST00000441217.1
AC073046.25
AC073046.25
chr2_-_61765732 0.14 ENST00000443240.1
ENST00000436018.1
XPO1
exportin 1 (CRM1 homolog, yeast)
chr16_+_30969055 0.14 ENST00000452917.1
SETD1A
SET domain containing 1A
chr2_+_173292280 0.14 ENST00000264107.7
ITGA6
integrin, alpha 6
chr3_-_182817367 0.14 ENST00000265594.4
MCCC1
methylcrotonoyl-CoA carboxylase 1 (alpha)
chr2_-_167232484 0.14 ENST00000375387.4
ENST00000303354.6
ENST00000409672.1
SCN9A
sodium channel, voltage-gated, type IX, alpha subunit
chr15_+_63796779 0.14 ENST00000561442.1
ENST00000560070.1
ENST00000540797.1
ENST00000380324.3
ENST00000268049.7
ENST00000536001.1
ENST00000539772.1
USP3
ubiquitin specific peptidase 3
chr16_+_202686 0.14 ENST00000252951.2
HBZ
hemoglobin, zeta
chr12_-_80328700 0.14 ENST00000550107.1
PPP1R12A
protein phosphatase 1, regulatory subunit 12A
chr11_-_124543725 0.14 ENST00000545756.1
ENST00000263593.3
SIAE
sialic acid acetylesterase
chr12_-_112450915 0.14 ENST00000437003.2
ENST00000552374.2
ENST00000550831.3
ENST00000354825.3
ENST00000549537.2
ENST00000355445.3
TMEM116
transmembrane protein 116
chr12_+_8185288 0.14 ENST00000162391.3
FOXJ2
forkhead box J2
chr11_+_71903169 0.14 ENST00000393676.3
FOLR1
folate receptor 1 (adult)
chr6_-_39282221 0.13 ENST00000453413.2
KCNK17
potassium channel, subfamily K, member 17
chr6_-_30709980 0.13 ENST00000416018.1
ENST00000445853.1
ENST00000413165.1
ENST00000418160.1
FLOT1
flotillin 1
chr2_-_174828892 0.13 ENST00000418194.2
SP3
Sp3 transcription factor
chr4_+_129730779 0.13 ENST00000226319.6
PHF17
jade family PHD finger 1
chr6_-_30710447 0.13 ENST00000456573.2
FLOT1
flotillin 1
chr15_+_75074410 0.13 ENST00000439220.2
CSK
c-src tyrosine kinase
chr2_+_172378757 0.13 ENST00000409484.1
ENST00000321348.4
ENST00000375252.3
CYBRD1
cytochrome b reductase 1
chr4_+_129730839 0.13 ENST00000511647.1
PHF17
jade family PHD finger 1
chr5_-_95297534 0.13 ENST00000513343.1
ENST00000431061.2
ELL2
elongation factor, RNA polymerase II, 2
chr20_+_58515417 0.13 ENST00000360816.3
FAM217B
family with sequence similarity 217, member B
chr11_-_6440624 0.13 ENST00000311051.3
APBB1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr19_-_15442701 0.13 ENST00000594841.1
ENST00000601941.1
BRD4
bromodomain containing 4
chr8_-_101962777 0.13 ENST00000395951.3
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr7_+_35840542 0.13 ENST00000435235.1
ENST00000399034.2
ENST00000350320.6
ENST00000469679.2
SEPT7
septin 7
chr4_+_129731074 0.13 ENST00000512960.1
ENST00000503785.1
ENST00000514740.1
PHF17
jade family PHD finger 1
chr6_-_30710510 0.13 ENST00000376389.3
FLOT1
flotillin 1
chr15_-_44069513 0.13 ENST00000433927.1
ELL3
elongation factor RNA polymerase II-like 3
chr4_-_25865159 0.13 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr9_+_71736177 0.13 ENST00000606364.1
ENST00000453658.2
TJP2
tight junction protein 2
chr12_+_69004736 0.12 ENST00000545720.2
RAP1B
RAP1B, member of RAS oncogene family
chr6_+_130339710 0.12 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chr2_+_173292390 0.12 ENST00000442250.1
ENST00000458358.1
ENST00000409080.1
ITGA6
integrin, alpha 6
chr1_-_243326612 0.12 ENST00000492145.1
ENST00000490813.1
ENST00000464936.1
CEP170
centrosomal protein 170kDa
chr4_+_141294628 0.12 ENST00000512749.1
ENST00000608372.1
ENST00000506597.1
ENST00000394201.4
ENST00000510586.1
SCOC
short coiled-coil protein
chr19_+_35607166 0.12 ENST00000604255.1
ENST00000346446.5
ENST00000344013.6
ENST00000603449.1
ENST00000406988.1
ENST00000605550.1
ENST00000604804.1
ENST00000605552.1
FXYD3
FXYD domain containing ion transport regulator 3
chr17_-_7590745 0.12 ENST00000514944.1
ENST00000503591.1
ENST00000455263.2
ENST00000420246.2
ENST00000445888.2
ENST00000509690.1
ENST00000604348.1
ENST00000269305.4
TP53
tumor protein p53
chr5_-_130970723 0.12 ENST00000308008.6
ENST00000296859.6
ENST00000507093.1
ENST00000510071.1
ENST00000509018.1
ENST00000307984.5
RAPGEF6
Rap guanine nucleotide exchange factor (GEF) 6
chr1_+_33231221 0.12 ENST00000294521.3
KIAA1522
KIAA1522
chr1_+_156096336 0.12 ENST00000504687.1
ENST00000473598.2
LMNA
lamin A/C
chr1_-_109940550 0.12 ENST00000256637.6
SORT1
sortilin 1
chr17_-_46716647 0.12 ENST00000608940.1
RP11-357H14.17
RP11-357H14.17
chr7_-_16460863 0.12 ENST00000407010.2
ENST00000399310.3
ISPD
isoprenoid synthase domain containing
chr17_-_74023291 0.12 ENST00000586740.1
EVPL
envoplakin
chr9_-_99329098 0.12 ENST00000452280.1
CDC14B
cell division cycle 14B
chr11_-_6440283 0.12 ENST00000299402.6
ENST00000609360.1
ENST00000389906.2
ENST00000532020.2
APBB1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr13_-_20437772 0.11 ENST00000337963.4
ZMYM5
zinc finger, MYM-type 5
chr19_-_51522955 0.11 ENST00000358789.3
KLK10
kallikrein-related peptidase 10

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0050757 thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758) negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.1 0.3 GO:0006147 guanine catabolic process(GO:0006147)
0.1 0.3 GO:0035508 positive regulation of myosin-light-chain-phosphatase activity(GO:0035508)
0.1 0.4 GO:1990523 bone regeneration(GO:1990523)
0.1 0.6 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.1 0.4 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.1 0.6 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.1 0.3 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.1 0.3 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.1 1.1 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.1 0.2 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.1 0.4 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.1 0.2 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.0 0.2 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.0 0.1 GO:0071231 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713) cellular response to folic acid(GO:0071231)
0.0 0.4 GO:0003415 chondrocyte hypertrophy(GO:0003415)
0.0 0.8 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.8 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:0001300 chronological cell aging(GO:0001300)
0.0 0.4 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.2 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.1 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.0 0.2 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.2 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.0 0.3 GO:0035634 response to stilbenoid(GO:0035634)
0.0 0.1 GO:0010039 response to iron ion(GO:0010039)
0.0 0.3 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.5 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.0 0.1 GO:0051097 negative regulation of helicase activity(GO:0051097) oligodendrocyte apoptotic process(GO:0097252)
0.0 0.1 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.0 0.1 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 0.1 GO:1903179 negative regulation of late endosome to lysosome transport(GO:1902823) regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181) negative regulation of protein catabolic process in the vacuole(GO:1904351) negative regulation of lysosomal protein catabolic process(GO:1905166)
0.0 0.2 GO:0010133 proline catabolic process(GO:0006562) proline catabolic process to glutamate(GO:0010133)
0.0 0.1 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.0 0.6 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.4 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.0 0.2 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.1 GO:0006272 leading strand elongation(GO:0006272)
0.0 0.2 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0 0.4 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.2 GO:0071105 negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003340) response to interleukin-9(GO:0071104) response to interleukin-11(GO:0071105)
0.0 0.2 GO:1900084 regulation of peptidyl-tyrosine autophosphorylation(GO:1900084) positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
0.0 0.1 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.1 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0 0.2 GO:1902846 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.0 0.8 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.1 GO:1902868 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) regulation of amacrine cell differentiation(GO:1902869) positive regulation of amacrine cell differentiation(GO:1902871)
0.0 0.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.2 GO:0021592 fourth ventricle development(GO:0021592)
0.0 0.2 GO:0000821 regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
0.0 0.2 GO:0001714 endodermal cell fate specification(GO:0001714)
0.0 0.1 GO:0048597 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.0 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.1 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.2 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.1 GO:1990936 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.0 0.1 GO:1990641 cellular response to bile acid(GO:1903413) response to iron ion starvation(GO:1990641)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.1 GO:0034287 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) detection of glucose(GO:0051594)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.2 GO:0070269 L-methionine biosynthetic process from methylthioadenosine(GO:0019509) pyroptosis(GO:0070269)
0.0 0.1 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.0 0.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.2 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.1 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.0 0.3 GO:1900016 negative regulation of cytokine production involved in inflammatory response(GO:1900016)
0.0 0.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.1 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.0 0.2 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.3 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.2 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.3 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.0 GO:2000017 positive regulation of determination of dorsal identity(GO:2000017)
0.0 0.3 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.1 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.3 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.1 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.1 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.4 GO:0030033 microvillus assembly(GO:0030033)
0.0 0.1 GO:0034141 positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.0 0.1 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.0 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.0 0.3 GO:0097186 amelogenesis(GO:0097186)
0.0 0.1 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.1 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0034676 integrin alpha6-beta4 complex(GO:0034676)
0.1 0.3 GO:0002169 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.0 0.2 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.8 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.1 GO:0072563 endothelial microparticle(GO:0072563)
0.0 0.2 GO:0034753 nuclear aryl hydrocarbon receptor complex(GO:0034753)
0.0 0.7 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.3 GO:0031415 NatA complex(GO:0031415)
0.0 0.7 GO:0016600 flotillin complex(GO:0016600)
0.0 0.3 GO:1990761 growth cone lamellipodium(GO:1990761)
0.0 0.2 GO:0097513 myosin II filament(GO:0097513)
0.0 0.1 GO:0097232 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.0 0.2 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.4 GO:0097227 sperm annulus(GO:0097227)
0.0 0.3 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.2 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.0 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.6 GO:0030057 desmosome(GO:0030057)
0.0 0.0 GO:0045160 myosin I complex(GO:0045160)
0.0 0.1 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.4 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.5 GO:0035869 ciliary transition zone(GO:0035869)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0008892 guanine deaminase activity(GO:0008892)
0.1 1.1 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 0.3 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.1 0.4 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.1 0.8 GO:0038132 neuregulin binding(GO:0038132)
0.1 0.8 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.2 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.1 0.3 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.0 0.2 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.0 0.1 GO:0061714 folic acid receptor activity(GO:0061714)
0.0 0.2 GO:0004307 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.3 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.2 GO:0043208 glycosphingolipid binding(GO:0043208) ceramide binding(GO:0097001)
0.0 0.2 GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 0.2 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.1 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.0 0.3 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.1 GO:0004974 leukotriene B4 receptor activity(GO:0001632) leukotriene receptor activity(GO:0004974)
0.0 0.1 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.1 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.0 0.1 GO:0052594 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.0 0.1 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.1 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.1 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 0.2 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.4 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.7 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.1 GO:0005534 galactose binding(GO:0005534)
0.0 0.0 GO:0070984 SET domain binding(GO:0070984)
0.0 0.1 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.1 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.2 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.0 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.1 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.0 0.4 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.8 PID AURORA B PATHWAY Aurora B signaling
0.0 1.0 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.3 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 1.3 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.3 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.2 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.4 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.1 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.1 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism