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avrg: A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for HOXB13

Z-value: 0.78

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Transcription factors associated with HOXB13

Gene Symbol Gene ID Gene Info
ENSG00000159184.7 HOXB13

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOXB13hg19_v2_chr17_-_46806540_46806558-0.928.1e-02Click!

Activity profile of HOXB13 motif

Sorted Z-values of HOXB13 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXB13

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr5_-_126409159 0.68 ENST00000607731.1
ENST00000535381.1
ENST00000296662.5
ENST00000509733.3
C5orf63
chromosome 5 open reading frame 63
chr8_+_86376081 0.64 ENST00000285379.5
CA2
carbonic anhydrase II
chr1_+_23037323 0.47 ENST00000544305.1
ENST00000374630.3
ENST00000400191.3
ENST00000374632.3
EPHB2
EPH receptor B2
chr5_-_145214893 0.47 ENST00000394450.2
PRELID2
PRELI domain containing 2
chr15_+_66994561 0.36 ENST00000288840.5
SMAD6
SMAD family member 6
chr8_+_119294456 0.33 ENST00000366457.2
AC023590.1
Uncharacterized protein
chr3_-_114790179 0.33 ENST00000462705.1
ZBTB20
zinc finger and BTB domain containing 20
chr1_-_155880672 0.30 ENST00000609492.1
ENST00000368322.3
RIT1
Ras-like without CAAX 1
chr19_-_5903714 0.30 ENST00000586349.1
ENST00000585661.1
ENST00000308961.4
ENST00000592634.1
ENST00000418389.2
ENST00000252675.5
AC024592.12
NDUFA11
FUT5
Uncharacterized protein
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa
fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
chrM_+_12331 0.29 ENST00000361567.2
MT-ND5
mitochondrially encoded NADH dehydrogenase 5
chr18_+_68002675 0.25 ENST00000584919.1
RP11-41O4.1
Uncharacterized protein
chrM_+_14741 0.24 ENST00000361789.2
MT-CYB
mitochondrially encoded cytochrome b
chr7_+_35756186 0.24 ENST00000430518.1
AC018647.3
AC018647.3
chr17_-_39646116 0.23 ENST00000328119.6
KRT36
keratin 36
chrM_-_14670 0.21 ENST00000361681.2
MT-ND6
mitochondrially encoded NADH dehydrogenase 6
chr7_-_50860565 0.20 ENST00000403097.1
GRB10
growth factor receptor-bound protein 10
chr17_-_73663245 0.19 ENST00000584999.1
ENST00000317905.5
ENST00000420326.2
ENST00000340830.5
RECQL5
RecQ protein-like 5
chr1_-_36863481 0.19 ENST00000315732.2
LSM10
LSM10, U7 small nuclear RNA associated
chr4_+_169575875 0.18 ENST00000503457.1
PALLD
palladin, cytoskeletal associated protein
chr5_-_145214848 0.18 ENST00000505416.1
ENST00000334744.4
ENST00000358004.2
ENST00000511435.1
PRELID2
PRELI domain containing 2
chr18_+_3252206 0.18 ENST00000578562.2
MYL12A
myosin, light chain 12A, regulatory, non-sarcomeric
chr18_-_52989525 0.18 ENST00000457482.3
TCF4
transcription factor 4
chr18_+_3252265 0.17 ENST00000580887.1
ENST00000536605.1
MYL12A
myosin, light chain 12A, regulatory, non-sarcomeric
chr4_+_110749143 0.16 ENST00000317735.4
RRH
retinal pigment epithelium-derived rhodopsin homolog
chr12_-_52715179 0.16 ENST00000293670.3
KRT83
keratin 83
chr8_+_77593448 0.16 ENST00000521891.2
ZFHX4
zinc finger homeobox 4
chr13_-_103719196 0.15 ENST00000245312.3
SLC10A2
solute carrier family 10 (sodium/bile acid cotransporter), member 2
chr7_+_35756092 0.15 ENST00000458087.3
AC018647.3
AC018647.3
chr15_-_55541227 0.15 ENST00000566877.1
RAB27A
RAB27A, member RAS oncogene family
chr9_+_22646189 0.14 ENST00000436786.1
RP11-399D6.2
RP11-399D6.2
chr22_-_38240316 0.14 ENST00000411961.2
ENST00000434930.1
ANKRD54
ankyrin repeat domain 54
chr16_+_30669720 0.14 ENST00000356166.6
FBRS
fibrosin
chr12_+_70219052 0.14 ENST00000552032.2
ENST00000547771.2
MYRFL
myelin regulatory factor-like
chr5_-_159766528 0.12 ENST00000505287.2
CCNJL
cyclin J-like
chr19_+_1440838 0.11 ENST00000594262.1
AC027307.3
Uncharacterized protein
chr1_-_45956868 0.11 ENST00000451835.2
TESK2
testis-specific kinase 2
chr1_+_52682052 0.11 ENST00000371591.1
ZFYVE9
zinc finger, FYVE domain containing 9
chr16_-_24942411 0.11 ENST00000571843.1
ARHGAP17
Rho GTPase activating protein 17
chr1_-_45956800 0.11 ENST00000538496.1
TESK2
testis-specific kinase 2
chr17_-_10560619 0.10 ENST00000583535.1
MYH3
myosin, heavy chain 3, skeletal muscle, embryonic
chr16_-_24942273 0.10 ENST00000571406.1
ARHGAP17
Rho GTPase activating protein 17
chr4_+_68424434 0.10 ENST00000265404.2
ENST00000396225.1
STAP1
signal transducing adaptor family member 1
chr2_+_173724771 0.10 ENST00000538974.1
ENST00000540783.1
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr14_-_68000442 0.09 ENST00000554278.1
TMEM229B
transmembrane protein 229B
chr17_-_73663168 0.08 ENST00000578201.1
ENST00000423245.2
RECQL5
RecQ protein-like 5
chr9_+_125132803 0.08 ENST00000540753.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr15_+_48483736 0.08 ENST00000417307.2
ENST00000559641.1
CTXN2
SLC12A1
cortexin 2
solute carrier family 12 (sodium/potassium/chloride transporter), member 1
chr1_+_84630574 0.08 ENST00000413538.1
ENST00000417530.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr10_-_94301107 0.07 ENST00000436178.1
IDE
insulin-degrading enzyme
chr6_+_122793058 0.07 ENST00000392491.2
PKIB
protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr21_+_30673091 0.07 ENST00000447177.1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr10_+_104005272 0.07 ENST00000369983.3
GBF1
golgi brefeldin A resistant guanine nucleotide exchange factor 1
chr4_-_69111401 0.06 ENST00000332644.5
TMPRSS11B
transmembrane protease, serine 11B
chr16_+_2205755 0.06 ENST00000326181.6
TRAF7
TNF receptor-associated factor 7, E3 ubiquitin protein ligase
chr1_+_84630352 0.05 ENST00000450730.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr1_+_78769549 0.05 ENST00000370758.1
PTGFR
prostaglandin F receptor (FP)
chr9_+_20927764 0.05 ENST00000603044.1
ENST00000604254.1
FOCAD
focadhesin
chr9_+_123884038 0.04 ENST00000373847.1
CNTRL
centriolin
chr22_-_38240412 0.04 ENST00000215941.4
ANKRD54
ankyrin repeat domain 54
chr7_-_130353553 0.03 ENST00000330992.7
ENST00000445977.2
COPG2
coatomer protein complex, subunit gamma 2
chr3_+_89156799 0.03 ENST00000452448.2
ENST00000494014.1
EPHA3
EPH receptor A3
chr8_-_114449112 0.03 ENST00000455883.2
ENST00000352409.3
ENST00000297405.5
CSMD3
CUB and Sushi multiple domains 3
chr7_+_128784712 0.02 ENST00000289407.4
TSPAN33
tetraspanin 33
chr6_-_27782548 0.02 ENST00000333151.3
HIST1H2AJ
histone cluster 1, H2aj
chr3_-_150690786 0.02 ENST00000327047.1
CLRN1
clarin 1
chr1_-_149783914 0.02 ENST00000369167.1
ENST00000427880.2
ENST00000545683.1
HIST2H2BF
histone cluster 2, H2bf
chr15_+_71839566 0.01 ENST00000357769.4
THSD4
thrombospondin, type I, domain containing 4
chr2_-_176046391 0.01 ENST00000392541.3
ENST00000409194.1
ATP5G3
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
chr3_-_123710199 0.01 ENST00000184183.4
ROPN1
rhophilin associated tail protein 1
chr2_+_74685413 0.01 ENST00000233615.2
WBP1
WW domain binding protein 1
chr21_+_30672433 0.01 ENST00000451655.1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr1_-_45956822 0.00 ENST00000372086.3
ENST00000341771.6
TESK2
testis-specific kinase 2
chr9_-_130829588 0.00 ENST00000373078.4
NAIF1
nuclear apoptosis inducing factor 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0042938 dipeptide transport(GO:0042938)
0.2 0.5 GO:0051389 inactivation of MAPKK activity(GO:0051389)
0.1 0.3 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.1 0.4 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.1 GO:1903980 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973) positive regulation of microglial cell activation(GO:1903980)
0.0 0.3 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.1 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.1 GO:1901143 insulin catabolic process(GO:1901143)
0.0 0.1 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.2 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.2 GO:0046325 negative regulation of glucose import(GO:0046325)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.2 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 0.4 GO:0070698 transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity(GO:0030617) type I activin receptor binding(GO:0070698)
0.1 0.6 GO:0004064 arylesterase activity(GO:0004064)
0.1 0.3 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 0.2 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 0.5 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.3 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.2 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.1 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.1 GO:0031626 beta-endorphin binding(GO:0031626)
0.0 0.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.0 0.1 GO:0017018 myosin phosphatase activity(GO:0017018)
0.0 0.1 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.2 REACTOME OPSINS Genes involved in Opsins
0.0 0.3 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.2 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs