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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)
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Results for ZNF711_TFAP2A_TFAP2D
Z-value: 3.75
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Transcription factors associated with ZNF711_TFAP2A_TFAP2D
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| TFAP2A | hg19_v2_chr6_-_10415470_10415508 | 0.96 | 3.9e-02 | Click! |
| ZNF711 | hg19_v2_chrX_+_84499038_84499078 | 0.95 | 4.8e-02 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of ZNF711_TFAP2A_TFAP2D
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 13.7 | GO:0006334 | nucleosome assembly(GO:0006334) |
| 0.3 | 10.1 | GO:0061641 | CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641) |
| 0.8 | 7.9 | GO:0046940 | nucleoside monophosphate phosphorylation(GO:0046940) |
| 0.2 | 7.1 | GO:1900153 | regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153) |
| 0.3 | 6.8 | GO:0051383 | kinetochore organization(GO:0051383) |
| 0.1 | 6.6 | GO:0048278 | vesicle docking(GO:0048278) |
| 0.2 | 6.4 | GO:0035268 | protein mannosylation(GO:0035268) |
| 0.2 | 5.4 | GO:0016254 | preassembly of GPI anchor in ER membrane(GO:0016254) |
| 0.5 | 5.3 | GO:0071394 | cellular response to testosterone stimulus(GO:0071394) |
| 0.3 | 4.9 | GO:1901407 | regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 13.7 | GO:0005759 | mitochondrial matrix(GO:0005759) |
| 0.1 | 13.5 | GO:0000775 | chromosome, centromeric region(GO:0000775) |
| 0.1 | 10.8 | GO:0000922 | spindle pole(GO:0000922) |
| 0.0 | 9.4 | GO:0005813 | centrosome(GO:0005813) |
| 0.2 | 9.1 | GO:0035869 | ciliary transition zone(GO:0035869) |
| 0.1 | 8.5 | GO:0005819 | spindle(GO:0005819) |
| 0.0 | 8.4 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.1 | 7.7 | GO:0016328 | lateral plasma membrane(GO:0016328) |
| 0.2 | 7.2 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
| 0.1 | 7.0 | GO:0005801 | cis-Golgi network(GO:0005801) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 10.6 | GO:0005096 | GTPase activator activity(GO:0005096) |
| 0.0 | 8.7 | GO:0042393 | histone binding(GO:0042393) |
| 0.3 | 8.2 | GO:0035173 | histone kinase activity(GO:0035173) |
| 0.2 | 6.2 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
| 0.2 | 6.2 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
| 0.5 | 6.0 | GO:0005007 | fibroblast growth factor-activated receptor activity(GO:0005007) |
| 0.2 | 6.0 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 0.1 | 5.8 | GO:0008565 | protein transporter activity(GO:0008565) |
| 0.1 | 5.7 | GO:0030276 | clathrin binding(GO:0030276) |
| 0.9 | 5.3 | GO:0046899 | nucleoside triphosphate adenylate kinase activity(GO:0046899) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 21.7 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.2 | 16.2 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.1 | 12.8 | PID E2F PATHWAY | E2F transcription factor network |
| 0.2 | 10.9 | PID VEGFR1 PATHWAY | VEGFR1 specific signals |
| 0.1 | 10.2 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.1 | 8.1 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.1 | 8.0 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.1 | 7.2 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.1 | 6.4 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.1 | 5.9 | PID P53 REGULATION PATHWAY | p53 pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 28.7 | REACTOME GENERIC TRANSCRIPTION PATHWAY | Genes involved in Generic Transcription Pathway |
| 0.1 | 13.7 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.2 | 13.3 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.3 | 10.0 | REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
| 0.1 | 9.7 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.2 | 7.3 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.1 | 7.3 | REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION | Genes involved in Transport to the Golgi and subsequent modification |
| 0.3 | 7.0 | REACTOME G2 M DNA DAMAGE CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
| 0.1 | 6.9 | REACTOME PI3K AKT ACTIVATION | Genes involved in PI3K/AKT activation |
| 0.1 | 6.5 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |