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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for ZNF274

Z-value: 1.10

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Transcription factors associated with ZNF274

Gene Symbol Gene ID Gene Info
ZNF274
ENSG00000171606.13 zinc finger protein 274

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF274hg19_v2_chr19_+_58694396_586944850.742.6e-01Click!

Activity profile of ZNF274 motif

Sorted Z-values of ZNF274 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_40195101 1.20 ENST00000360675.3
ENST00000601802.1
LGALS14
lectin, galactoside-binding, soluble, 14
chr2_-_96971259 0.79 ENST00000349783.5
SNRNP200
small nuclear ribonucleoprotein 200kDa (U5)
chr5_+_121465207 0.67 ENST00000296600.4
ZNF474
zinc finger protein 474
chr15_+_89164520 0.67 ENST00000332810.3
AEN
apoptosis enhancing nuclease
chr12_-_49581152 0.62 ENST00000550811.1
TUBA1A
tubulin, alpha 1a
chr2_+_9696028 0.54 ENST00000607241.1
RP11-214N9.1
RP11-214N9.1
chr17_+_73028676 0.53 ENST00000581589.1
KCTD2
potassium channel tetramerization domain containing 2
chr6_+_30687978 0.51 ENST00000327892.8
ENST00000435534.1
TUBB
tubulin, beta class I
chr19_-_56109119 0.50 ENST00000587678.1
FIZ1
FLT3-interacting zinc finger 1
chr11_+_59705928 0.49 ENST00000398992.1
OOSP1
oocyte secreted protein 1
chr3_+_37903432 0.48 ENST00000443503.2
CTDSPL
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr17_-_41132410 0.47 ENST00000409446.3
ENST00000453594.1
ENST00000409399.1
ENST00000421990.2
PTGES3L
PTGES3L-AARSD1
prostaglandin E synthase 3 (cytosolic)-like
PTGES3L-AARSD1 readthrough
chr16_+_29127282 0.46 ENST00000562902.1
RP11-426C22.5
RP11-426C22.5
chr12_-_89919965 0.44 ENST00000548729.1
POC1B-GALNT4
POC1B-GALNT4 readthrough
chr9_+_125512019 0.44 ENST00000373684.1
ENST00000304720.2
OR1L6
olfactory receptor, family 1, subfamily L, member 6
chr1_+_45205478 0.44 ENST00000452259.1
ENST00000372224.4
KIF2C
kinesin family member 2C
chr16_+_29819372 0.38 ENST00000568544.1
ENST00000569978.1
MAZ
MYC-associated zinc finger protein (purine-binding transcription factor)
chr19_+_41949054 0.38 ENST00000378187.2
C19orf69
chromosome 19 open reading frame 69
chrX_+_52920336 0.36 ENST00000452154.2
FAM156B
family with sequence similarity 156, member B
chr5_-_173043591 0.35 ENST00000285908.5
ENST00000480951.1
ENST00000311086.4
BOD1
biorientation of chromosomes in cell division 1
chr1_+_45205498 0.35 ENST00000372218.4
KIF2C
kinesin family member 2C
chr15_+_89164560 0.35 ENST00000379231.3
ENST00000559528.1
AEN
apoptosis enhancing nuclease
chr6_+_31553978 0.33 ENST00000376096.1
ENST00000376099.1
ENST00000376110.3
LST1
leukocyte specific transcript 1
chr16_+_31470179 0.31 ENST00000538189.1
ENST00000268314.4
ARMC5
armadillo repeat containing 5
chr13_-_74993252 0.27 ENST00000325811.1
AL355390.1
Uncharacterized protein
chr5_-_74162605 0.23 ENST00000389156.4
ENST00000510496.1
ENST00000380515.3
FAM169A
family with sequence similarity 169, member A
chr16_+_31470143 0.22 ENST00000457010.2
ENST00000563544.1
ARMC5
armadillo repeat containing 5
chr16_+_29818857 0.22 ENST00000567444.1
MAZ
MYC-associated zinc finger protein (purine-binding transcription factor)
chrX_+_119737806 0.19 ENST00000371317.5
MCTS1
malignant T cell amplified sequence 1
chr7_-_73038822 0.18 ENST00000414749.2
ENST00000429400.2
ENST00000434326.1
MLXIPL
MLX interacting protein-like
chr17_+_41132564 0.18 ENST00000361677.1
ENST00000589705.1
RUNDC1
RUN domain containing 1
chr22_+_39353527 0.17 ENST00000249116.2
APOBEC3A
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A
chr20_+_60174827 0.16 ENST00000543233.1
CDH4
cadherin 4, type 1, R-cadherin (retinal)
chr1_-_114414316 0.15 ENST00000528414.1
ENST00000538253.1
ENST00000460620.1
ENST00000420377.2
ENST00000525799.1
ENST00000359785.5
PTPN22
protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
chr1_-_54355430 0.13 ENST00000371399.1
ENST00000072644.1
ENST00000412288.1
YIPF1
Yip1 domain family, member 1
chr10_-_29811456 0.12 ENST00000535393.1
SVIL
supervillin
chr5_-_74162739 0.12 ENST00000513277.1
FAM169A
family with sequence similarity 169, member A
chr3_-_137893721 0.12 ENST00000505015.2
ENST00000260803.4
DBR1
debranching RNA lariats 1
chr4_+_15704679 0.11 ENST00000382346.3
BST1
bone marrow stromal cell antigen 1
chr1_+_42928945 0.11 ENST00000428554.2
CCDC30
coiled-coil domain containing 30
chr12_-_89920030 0.09 ENST00000413530.1
ENST00000547474.1
GALNT4
POC1B-GALNT4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
POC1B-GALNT4 readthrough
chr11_+_16760161 0.09 ENST00000524439.1
ENST00000422258.2
ENST00000528634.1
ENST00000525684.1
C11orf58
chromosome 11 open reading frame 58
chr7_+_30791743 0.09 ENST00000013222.5
ENST00000409539.1
INMT
indolethylamine N-methyltransferase
chr16_+_29819446 0.08 ENST00000568282.1
MAZ
MYC-associated zinc finger protein (purine-binding transcription factor)
chr14_-_64846033 0.06 ENST00000556556.1
CTD-2555O16.1
CTD-2555O16.1
chr13_+_103459704 0.05 ENST00000602836.1
BIVM-ERCC5
BIVM-ERCC5 readthrough
chr6_-_127780510 0.05 ENST00000487331.2
ENST00000483725.3
KIAA0408
KIAA0408
chr4_+_15704573 0.04 ENST00000265016.4
BST1
bone marrow stromal cell antigen 1
chr2_+_11864458 0.04 ENST00000396098.1
ENST00000396099.1
ENST00000425416.2
LPIN1
lipin 1
chr3_+_50284321 0.03 ENST00000451956.1
GNAI2
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr3_-_38992052 0.03 ENST00000302328.3
ENST00000450244.1
ENST00000444237.2
SCN11A
sodium channel, voltage-gated, type XI, alpha subunit
chr14_-_73997901 0.02 ENST00000557603.1
ENST00000556455.1
HEATR4
HEAT repeat containing 4
chr10_+_5488564 0.02 ENST00000449083.1
ENST00000380359.3
NET1
neuroepithelial cell transforming 1
chr19_+_7584088 0.01 ENST00000394341.2
ZNF358
zinc finger protein 358
chr3_-_38991853 0.00 ENST00000456224.3
SCN11A
sodium channel, voltage-gated, type XI, alpha subunit
chr19_-_19774473 0.00 ENST00000357324.6
ATP13A1
ATPase type 13A1

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF274

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0000354 cis assembly of pre-catalytic spliceosome(GO:0000354)
0.1 1.2 GO:0070234 positive regulation of T cell apoptotic process(GO:0070234)
0.1 0.8 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 0.2 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.1 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.0 0.2 GO:0070383 DNA cytosine deamination(GO:0070383)
0.0 0.2 GO:0090324 negative regulation of oxidative phosphorylation(GO:0090324)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.8 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 0.9 GO:1990752 microtubule end(GO:1990752)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.1 GO:0050135 NAD(P)+ nucleosidase activity(GO:0050135)
0.0 0.2 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.0 0.5 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.5 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.1 GO:0008172 S-methyltransferase activity(GO:0008172)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.0 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME KINESINS Genes involved in Kinesins
0.0 0.6 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.8 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway