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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)
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Results for ZNF143
Z-value: 3.14
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Transcription factors associated with ZNF143
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ZNF143 | hg19_v2_chr11_+_9482551_9482604 | 0.57 | 4.3e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of ZNF143
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 5.2 | GO:1990001 | inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001) |
| 1.2 | 3.5 | GO:0071790 | spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790) |
| 0.3 | 3.4 | GO:2000582 | positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582) |
| 0.3 | 2.9 | GO:0032226 | positive regulation of synaptic transmission, dopaminergic(GO:0032226) |
| 0.2 | 2.8 | GO:1990416 | cellular response to brain-derived neurotrophic factor stimulus(GO:1990416) |
| 0.2 | 2.6 | GO:0034501 | protein localization to kinetochore(GO:0034501) |
| 0.2 | 2.4 | GO:0018206 | peptidyl-methionine modification(GO:0018206) |
| 0.1 | 2.3 | GO:0043101 | purine-containing compound salvage(GO:0043101) |
| 0.2 | 2.1 | GO:1901098 | positive regulation of autophagosome maturation(GO:1901098) |
| 0.2 | 2.0 | GO:0006207 | 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 5.6 | GO:0032133 | chromosome passenger complex(GO:0032133) |
| 1.2 | 3.5 | GO:0070762 | nuclear pore transmembrane ring(GO:0070762) |
| 0.1 | 3.5 | GO:0035861 | site of double-strand break(GO:0035861) |
| 0.1 | 3.4 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
| 0.1 | 3.1 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
| 0.0 | 2.4 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.0 | 2.4 | GO:0000777 | condensed chromosome kinetochore(GO:0000777) |
| 0.6 | 2.3 | GO:1990423 | RZZ complex(GO:1990423) |
| 0.3 | 2.3 | GO:1902560 | GMP reductase complex(GO:1902560) |
| 0.1 | 2.3 | GO:0016600 | flotillin complex(GO:0016600) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.6 | GO:0008536 | Ran GTPase binding(GO:0008536) |
| 0.1 | 3.5 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
| 0.1 | 3.2 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
| 0.3 | 2.3 | GO:0016657 | GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657) |
| 0.0 | 2.3 | GO:0035255 | ionotropic glutamate receptor binding(GO:0035255) |
| 0.2 | 2.1 | GO:0019237 | centromeric DNA binding(GO:0019237) |
| 0.5 | 2.0 | GO:0009041 | uridylate kinase activity(GO:0009041) |
| 0.1 | 1.9 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.0 | 1.7 | GO:0008235 | metalloexopeptidase activity(GO:0008235) |
| 0.0 | 1.7 | GO:0003684 | damaged DNA binding(GO:0003684) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 9.1 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.1 | 3.9 | PID BARD1 PATHWAY | BARD1 signaling events |
| 0.0 | 2.9 | PID RAC1 PATHWAY | RAC1 signaling pathway |
| 0.0 | 2.1 | SIG PIP3 SIGNALING IN B LYMPHOCYTES | Genes related to PIP3 signaling in B lymphocytes |
| 0.0 | 2.0 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.0 | 1.9 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.0 | 1.3 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.0 | 1.2 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
| 0.0 | 1.2 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.0 | 1.0 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 11.4 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.0 | 4.2 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.1 | 4.0 | REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS | Genes involved in Homologous recombination repair of replication-independent double-strand breaks |
| 0.1 | 2.3 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
| 0.1 | 2.2 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.0 | 1.7 | REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
| 0.0 | 1.7 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.1 | 1.6 | REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND | Genes involved in Processive synthesis on the lagging strand |
| 0.0 | 1.2 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 0.1 | 1.1 | REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX | Genes involved in CDC6 association with the ORC:origin complex |