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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)
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Results for ZKSCAN3
Z-value: 1.43
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Transcription factors associated with ZKSCAN3
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ZKSCAN3 | hg19_v2_chr6_+_28317685_28317761 | -0.39 | 6.1e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr19_+_39786962 Show fit | 11.72 |
ENST00000333625.2
|
interferon, lambda 1 |
|
| chr19_-_39735646 Show fit | 2.10 |
ENST00000413851.2
|
interferon, lambda 3 |
|
| chr19_+_39759154 Show fit | 1.90 |
ENST00000331982.5
|
interferon, lambda 2 |
|
| chr1_-_935361 Show fit | 1.15 |
ENST00000484667.2
|
hes family bHLH transcription factor 4 |
|
| chr12_-_3982511 Show fit | 0.94 |
ENST00000427057.2
ENST00000228820.4 |
poly (ADP-ribose) polymerase family, member 11 |
|
| chr12_-_3982548 Show fit | 0.68 |
ENST00000397096.2
ENST00000447133.3 ENST00000450737.2 |
poly (ADP-ribose) polymerase family, member 11 |
|
| chr7_+_1084206 Show fit | 0.59 |
ENST00000444847.1
|
G protein-coupled receptor 146 |
|
| chr7_-_155089251 Show fit | 0.56 |
ENST00000609974.1
|
AC144652.1 |
|
| chr19_-_4182530 Show fit | 0.56 |
ENST00000601571.1
ENST00000601488.1 ENST00000305232.6 ENST00000381935.3 ENST00000337491.2 |
sirtuin 6 |
|
| chr9_+_127023704 Show fit | 0.55 |
ENST00000373596.1
ENST00000425237.1 |
NIMA-related kinase 6 |
Network of associatons between targets according to the STRING database.
First level regulatory network of ZKSCAN3
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.9 | 11.7 | GO:0032696 | negative regulation of interleukin-13 production(GO:0032696) |
| 0.0 | 2.1 | GO:0045071 | negative regulation of viral genome replication(GO:0045071) |
| 0.1 | 1.9 | GO:0002385 | mucosal immune response(GO:0002385) |
| 0.3 | 1.0 | GO:0003245 | cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245) histone H3-K9 deacetylation(GO:1990619) |
| 0.1 | 0.7 | GO:0060235 | lens induction in camera-type eye(GO:0060235) |
| 0.0 | 0.6 | GO:2000772 | regulation of cellular senescence(GO:2000772) |
| 0.1 | 0.5 | GO:2000503 | positive regulation of natural killer cell chemotaxis(GO:2000503) |
| 0.1 | 0.5 | GO:0090038 | negative regulation of protein kinase C signaling(GO:0090038) |
| 0.1 | 0.4 | GO:1904207 | regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209) |
| 0.0 | 0.4 | GO:0006049 | UDP-N-acetylglucosamine catabolic process(GO:0006049) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.9 | 11.7 | GO:0032002 | interleukin-28 receptor complex(GO:0032002) |
| 0.0 | 1.6 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.3 | 1.0 | GO:0031933 | telomeric heterochromatin(GO:0031933) |
| 0.0 | 0.4 | GO:0033269 | internode region of axon(GO:0033269) |
| 0.0 | 0.3 | GO:0019774 | proteasome core complex, beta-subunit complex(GO:0019774) |
| 0.0 | 0.2 | GO:0071203 | WASH complex(GO:0071203) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 15.7 | GO:0005125 | cytokine activity(GO:0005125) |
| 0.0 | 1.6 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.3 | 1.0 | GO:0032129 | histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969) |
| 0.0 | 0.6 | GO:0001222 | transcription corepressor binding(GO:0001222) |
| 0.1 | 0.5 | GO:0031726 | CCR1 chemokine receptor binding(GO:0031726) |
| 0.0 | 0.4 | GO:0003827 | alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827) |
| 0.0 | 0.4 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
| 0.0 | 0.3 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
| 0.0 | 0.3 | GO:0070003 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 0.0 | 0.2 | GO:0004345 | glucose-6-phosphate dehydrogenase activity(GO:0004345) |