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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for ZKSCAN1

Z-value: 2.44

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Transcription factors associated with ZKSCAN1

Gene Symbol Gene ID Gene Info
ZKSCAN1
ENSG00000106261.12 zinc finger with KRAB and SCAN domains 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZKSCAN1hg19_v2_chr7_+_99613195_99613206-0.981.8e-02Click!

Activity profile of ZKSCAN1 motif

Sorted Z-values of ZKSCAN1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr20_-_62199427 4.83 ENST00000427522.2
HELZ2
helicase with zinc finger 2, transcriptional coactivator
chr19_+_10196781 3.00 ENST00000253110.11
C19orf66
chromosome 19 open reading frame 66
chr12_+_113416265 2.69 ENST00000449768.2
OAS2
2'-5'-oligoadenylate synthetase 2, 69/71kDa
chrX_+_150866779 2.50 ENST00000370353.3
PRRG3
proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
chr5_+_135394840 2.48 ENST00000503087.1
TGFBI
transforming growth factor, beta-induced, 68kDa
chr20_-_48770244 2.40 ENST00000371650.5
ENST00000371652.4
ENST00000557021.1
TMEM189
transmembrane protein 189
chr20_-_56265680 2.34 ENST00000414037.1
PMEPA1
prostate transmembrane protein, androgen induced 1
chr22_+_21921994 2.30 ENST00000545681.1
UBE2L3
ubiquitin-conjugating enzyme E2L 3
chr10_+_106113515 2.27 ENST00000369704.3
ENST00000312902.5
CCDC147
coiled-coil domain containing 147
chr20_+_4152356 2.18 ENST00000379460.2
SMOX
spermine oxidase
chr12_+_13197218 1.73 ENST00000197268.8
KIAA1467
KIAA1467
chr1_+_209859510 1.72 ENST00000367028.2
ENST00000261465.1
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr16_-_4665023 1.68 ENST00000591897.1
UBALD1
UBA-like domain containing 1
chr5_-_172756506 1.63 ENST00000265087.4
STC2
stanniocalcin 2
chr20_+_43343517 1.62 ENST00000372865.4
WISP2
WNT1 inducible signaling pathway protein 2
chr11_+_70049269 1.60 ENST00000301838.4
FADD
Fas (TNFRSF6)-associated via death domain
chr20_+_43343476 1.52 ENST00000372868.2
WISP2
WNT1 inducible signaling pathway protein 2
chr19_-_19051993 1.44 ENST00000594794.1
ENST00000355887.6
ENST00000392351.3
ENST00000596482.1
HOMER3
homer homolog 3 (Drosophila)
chr17_-_26220366 1.28 ENST00000460380.2
ENST00000508862.1
ENST00000379102.3
ENST00000582441.1
LYRM9
RP1-66C13.4
LYR motif containing 9
Uncharacterized protein
chr19_+_850985 1.28 ENST00000590230.1
ELANE
elastase, neutrophil expressed
chr22_-_37640456 1.24 ENST00000405484.1
ENST00000441619.1
ENST00000406508.1
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr17_+_16945820 1.22 ENST00000577514.1
MPRIP
myosin phosphatase Rho interacting protein
chr22_-_37640277 1.18 ENST00000401529.3
ENST00000249071.6
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr19_+_39138271 1.18 ENST00000252699.2
ACTN4
actinin, alpha 4
chr15_-_34635314 1.12 ENST00000557912.1
ENST00000328848.4
NOP10
NOP10 ribonucleoprotein
chr16_-_4664860 1.07 ENST00000587615.1
ENST00000587649.1
ENST00000590965.1
ENST00000591401.1
ENST00000283474.7
UBALD1
UBA-like domain containing 1
chr19_+_39138320 1.04 ENST00000424234.2
ENST00000390009.3
ENST00000589528.1
ACTN4
actinin, alpha 4
chrX_+_47441712 1.03 ENST00000218388.4
ENST00000377018.2
ENST00000456754.2
ENST00000377017.1
ENST00000441738.1
TIMP1
TIMP metallopeptidase inhibitor 1
chr3_-_64673289 0.97 ENST00000295903.4
ADAMTS9
ADAM metallopeptidase with thrombospondin type 1 motif, 9
chr12_+_113416340 0.96 ENST00000552756.1
OAS2
2'-5'-oligoadenylate synthetase 2, 69/71kDa
chr2_+_71127699 0.86 ENST00000234392.2
VAX2
ventral anterior homeobox 2
chr2_-_158345341 0.86 ENST00000435117.1
CYTIP
cytohesin 1 interacting protein
chr12_+_9066472 0.85 ENST00000538657.1
PHC1
polyhomeotic homolog 1 (Drosophila)
chr5_+_149980622 0.85 ENST00000394243.1
SYNPO
synaptopodin
chr6_-_30640761 0.84 ENST00000415603.1
DHX16
DEAH (Asp-Glu-Ala-His) box polypeptide 16
chr12_+_8995832 0.84 ENST00000541459.1
A2ML1
alpha-2-macroglobulin-like 1
chr15_+_75494214 0.79 ENST00000394987.4
C15orf39
chromosome 15 open reading frame 39
chr11_+_61197508 0.78 ENST00000541135.1
ENST00000301761.2
RP11-286N22.8
SDHAF2
Uncharacterized protein
succinate dehydrogenase complex assembly factor 2
chr4_-_185395191 0.75 ENST00000510814.1
ENST00000507523.1
ENST00000506230.1
IRF2
interferon regulatory factor 2
chr2_-_200320768 0.72 ENST00000428695.1
SATB2
SATB homeobox 2
chr19_+_6740888 0.71 ENST00000596673.1
TRIP10
thyroid hormone receptor interactor 10
chr9_-_16253112 0.71 ENST00000380683.1
C9orf92
chromosome 9 open reading frame 92
chr4_+_41540160 0.65 ENST00000503057.1
ENST00000511496.1
LIMCH1
LIM and calponin homology domains 1
chr5_+_174151536 0.65 ENST00000239243.6
ENST00000507785.1
MSX2
msh homeobox 2
chr15_+_75498739 0.65 ENST00000565074.1
C15orf39
chromosome 15 open reading frame 39
chr15_-_78112553 0.64 ENST00000562933.1
LINGO1
leucine rich repeat and Ig domain containing 1
chr22_+_20861858 0.64 ENST00000414658.1
ENST00000432052.1
ENST00000425759.2
ENST00000292733.7
ENST00000542773.1
ENST00000263205.7
ENST00000406969.1
ENST00000382974.2
MED15
mediator complex subunit 15
chr17_+_36858694 0.62 ENST00000563897.1
CTB-58E17.1
CTB-58E17.1
chr19_+_8478154 0.62 ENST00000381035.4
ENST00000595142.1
ENST00000601724.1
ENST00000393944.1
ENST00000215555.2
ENST00000601283.1
ENST00000595213.1
MARCH2
membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
chr1_+_46668994 0.60 ENST00000371980.3
LURAP1
leucine rich adaptor protein 1
chr2_+_27071292 0.60 ENST00000431402.1
ENST00000434719.1
DPYSL5
dihydropyrimidinase-like 5
chr11_+_61197572 0.58 ENST00000542074.1
ENST00000534878.1
ENST00000537782.1
ENST00000543265.1
SDHAF2
succinate dehydrogenase complex assembly factor 2
chr14_+_103851712 0.58 ENST00000440884.3
ENST00000416682.2
ENST00000429436.2
ENST00000303622.9
MARK3
MAP/microtubule affinity-regulating kinase 3
chr1_-_53704157 0.58 ENST00000371466.4
ENST00000371470.3
MAGOH
mago-nashi homolog, proliferation-associated (Drosophila)
chr19_+_16830774 0.55 ENST00000524140.2
NWD1
NACHT and WD repeat domain containing 1
chr9_+_126131131 0.53 ENST00000373629.2
CRB2
crumbs homolog 2 (Drosophila)
chr3_-_47023455 0.53 ENST00000446836.1
ENST00000425441.1
CCDC12
coiled-coil domain containing 12
chr5_+_155753745 0.52 ENST00000435422.3
ENST00000337851.4
ENST00000447401.1
SGCD
sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
chr17_+_5031687 0.51 ENST00000250066.6
ENST00000304328.5
USP6
ubiquitin specific peptidase 6 (Tre-2 oncogene)
chr12_+_25055243 0.51 ENST00000599478.1
AC026310.1
Protein 101060047
chr7_-_72439997 0.50 ENST00000285805.3
TRIM74
tripartite motif containing 74
chr19_-_2739992 0.50 ENST00000545664.1
ENST00000589363.1
ENST00000455372.2
SLC39A3
solute carrier family 39 (zinc transporter), member 3
chr1_+_45140360 0.49 ENST00000418644.1
ENST00000458657.2
ENST00000441519.1
ENST00000535358.1
ENST00000445071.1
C1orf228
chromosome 1 open reading frame 228
chr5_-_131562935 0.48 ENST00000379104.2
ENST00000379100.2
ENST00000428369.1
P4HA2
prolyl 4-hydroxylase, alpha polypeptide II
chr7_-_72742085 0.47 ENST00000333149.2
TRIM50
tripartite motif containing 50
chr9_-_112260531 0.47 ENST00000374541.2
ENST00000262539.3
PTPN3
protein tyrosine phosphatase, non-receptor type 3
chr2_-_65659762 0.47 ENST00000440972.1
SPRED2
sprouty-related, EVH1 domain containing 2
chr3_-_48542197 0.46 ENST00000442747.1
ENST00000444115.1
SHISA5
shisa family member 5
chr16_-_46797149 0.45 ENST00000536476.1
MYLK3
myosin light chain kinase 3
chr22_+_30805086 0.45 ENST00000439838.1
ENST00000439023.3
RP4-539M6.19
Uncharacterized protein
chr6_-_30640811 0.44 ENST00000376442.3
DHX16
DEAH (Asp-Glu-Ala-His) box polypeptide 16
chr1_-_36615065 0.43 ENST00000373166.3
ENST00000373159.1
ENST00000373162.1
TRAPPC3
trafficking protein particle complex 3
chr14_+_54976603 0.43 ENST00000557317.1
CGRRF1
cell growth regulator with ring finger domain 1
chr19_+_3178736 0.42 ENST00000246115.3
S1PR4
sphingosine-1-phosphate receptor 4
chr19_+_16830815 0.36 ENST00000549814.1
NWD1
NACHT and WD repeat domain containing 1
chr2_+_27071045 0.35 ENST00000401478.1
DPYSL5
dihydropyrimidinase-like 5
chr10_+_118349920 0.34 ENST00000531984.1
PNLIPRP1
pancreatic lipase-related protein 1
chr11_-_64739542 0.33 ENST00000536065.1
C11orf85
chromosome 11 open reading frame 85
chr16_+_616995 0.33 ENST00000293874.2
ENST00000409527.2
ENST00000424439.2
ENST00000540585.1
PIGQ
NHLRC4
phosphatidylinositol glycan anchor biosynthesis, class Q
NHL repeat containing 4
chr20_-_3644046 0.32 ENST00000290417.2
ENST00000319242.3
GFRA4
GDNF family receptor alpha 4
chr15_-_80215984 0.31 ENST00000485386.1
ENST00000479961.1
ST20
ST20-MTHFS
suppressor of tumorigenicity 20
ST20-MTHFS readthrough
chr6_+_30844192 0.31 ENST00000502955.1
ENST00000505066.1
DDR1
discoidin domain receptor tyrosine kinase 1
chr16_+_8736232 0.31 ENST00000562973.1
METTL22
methyltransferase like 22
chr11_-_61197480 0.30 ENST00000439958.3
ENST00000394888.4
CPSF7
cleavage and polyadenylation specific factor 7, 59kDa
chr19_+_18794470 0.30 ENST00000321949.8
ENST00000338797.6
CRTC1
CREB regulated transcription coactivator 1
chr15_+_89921280 0.30 ENST00000560596.1
ENST00000558692.1
ENST00000538734.2
ENST00000559235.1
LINC00925
long intergenic non-protein coding RNA 925
chr1_+_27648648 0.30 ENST00000374076.4
TMEM222
transmembrane protein 222
chr16_+_56899114 0.30 ENST00000566786.1
ENST00000438926.2
ENST00000563236.1
ENST00000262502.5
SLC12A3
solute carrier family 12 (sodium/chloride transporter), member 3
chr2_-_183387430 0.29 ENST00000410103.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr19_-_344786 0.29 ENST00000264819.4
MIER2
mesoderm induction early response 1, family member 2
chr2_+_101179152 0.28 ENST00000264254.6
PDCL3
phosducin-like 3
chr12_+_52400719 0.28 ENST00000293662.4
GRASP
GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
chr1_+_16083098 0.28 ENST00000496928.2
ENST00000508310.1
FBLIM1
filamin binding LIM protein 1
chr16_+_2076869 0.26 ENST00000424542.2
ENST00000432365.2
SLC9A3R2
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
chr17_-_73150599 0.26 ENST00000392566.2
ENST00000581874.1
HN1
hematological and neurological expressed 1
chr17_-_73150629 0.26 ENST00000356033.4
ENST00000405458.3
ENST00000409753.3
HN1
hematological and neurological expressed 1
chr4_+_41361616 0.25 ENST00000513024.1
LIMCH1
LIM and calponin homology domains 1
chr1_+_27648709 0.25 ENST00000608611.1
ENST00000466759.1
ENST00000464813.1
ENST00000498220.1
TMEM222
transmembrane protein 222
chr1_-_202927388 0.25 ENST00000426229.1
ENST00000367254.3
ADIPOR1
adiponectin receptor 1
chr5_+_127039075 0.24 ENST00000514853.2
CTC-228N24.1
CTC-228N24.1
chr6_+_36922209 0.24 ENST00000373674.3
PI16
peptidase inhibitor 16
chr1_+_16083154 0.21 ENST00000375771.1
FBLIM1
filamin binding LIM protein 1
chr2_-_158345462 0.20 ENST00000439355.1
ENST00000540637.1
CYTIP
cytohesin 1 interacting protein
chr12_+_122326630 0.20 ENST00000541212.1
ENST00000340175.5
PSMD9
proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
chr1_-_151804222 0.19 ENST00000392697.3
RORC
RAR-related orphan receptor C
chr4_-_186732048 0.19 ENST00000448662.2
ENST00000439049.1
ENST00000420158.1
ENST00000431808.1
ENST00000319471.9
SORBS2
sorbin and SH3 domain containing 2
chr16_-_838329 0.18 ENST00000563560.1
ENST00000569601.1
ENST00000565809.1
ENST00000565377.1
ENST00000007264.2
ENST00000567114.1
RPUSD1
RNA pseudouridylate synthase domain containing 1
chr1_-_149908217 0.18 ENST00000369140.3
MTMR11
myotubularin related protein 11
chr13_+_76445187 0.17 ENST00000318245.4
C13orf45
chromosome 13 open reading frame 45
chr12_-_25055177 0.17 ENST00000538118.1
BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr3_+_184081175 0.17 ENST00000452961.1
ENST00000296223.3
POLR2H
polymerase (RNA) II (DNA directed) polypeptide H
chr17_+_26684604 0.16 ENST00000292114.3
ENST00000509083.1
TMEM199
transmembrane protein 199
chr22_+_33197683 0.15 ENST00000266085.6
TIMP3
TIMP metallopeptidase inhibitor 3
chr19_-_55660561 0.15 ENST00000587758.1
ENST00000356783.5
ENST00000291901.8
ENST00000588426.1
ENST00000588147.1
ENST00000536926.1
ENST00000588981.1
TNNT1
troponin T type 1 (skeletal, slow)
chr2_-_37193606 0.15 ENST00000379213.2
ENST00000263918.4
STRN
striatin, calmodulin binding protein
chr18_-_5895954 0.14 ENST00000581347.2
TMEM200C
transmembrane protein 200C
chr11_-_64739358 0.13 ENST00000301896.5
ENST00000530444.1
C11orf85
chromosome 11 open reading frame 85
chr17_-_40170506 0.12 ENST00000589773.1
ENST00000590348.1
DNAJC7
DnaJ (Hsp40) homolog, subfamily C, member 7
chr1_+_16348497 0.12 ENST00000439316.2
CLCNKA
chloride channel, voltage-sensitive Ka
chr7_+_72742178 0.12 ENST00000442793.1
ENST00000413573.2
ENST00000252037.4
FKBP6
FK506 binding protein 6, 36kDa
chr16_+_4364762 0.12 ENST00000262366.3
GLIS2
GLIS family zinc finger 2
chrX_-_40036520 0.11 ENST00000406200.2
ENST00000378455.4
ENST00000342274.4
BCOR
BCL6 corepressor
chr17_-_66597530 0.11 ENST00000592554.1
FAM20A
family with sequence similarity 20, member A
chr10_-_126432821 0.10 ENST00000280780.6
FAM53B
family with sequence similarity 53, member B
chr3_-_58563094 0.10 ENST00000464064.1
FAM107A
family with sequence similarity 107, member A
chr17_-_15370915 0.10 ENST00000312177.6
CDRT4
CMT1A duplicated region transcript 4
chr12_+_122326662 0.09 ENST00000261817.2
ENST00000538613.1
ENST00000542602.1
PSMD9
proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
chr11_+_33563821 0.09 ENST00000321505.4
ENST00000265654.5
ENST00000389726.3
KIAA1549L
KIAA1549-like
chr3_+_184081137 0.09 ENST00000443489.1
POLR2H
polymerase (RNA) II (DNA directed) polypeptide H
chr7_+_72742162 0.09 ENST00000431982.2
FKBP6
FK506 binding protein 6, 36kDa
chr14_+_101361107 0.09 ENST00000553584.1
ENST00000554852.1
MEG8
maternally expressed 8 (non-protein coding)
chr19_+_13135790 0.08 ENST00000358552.3
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr1_-_151804314 0.08 ENST00000318247.6
RORC
RAR-related orphan receptor C
chr6_+_10634158 0.08 ENST00000379591.3
GCNT6
glucosaminyl (N-acetyl) transferase 6
chr12_-_123450986 0.07 ENST00000344275.7
ENST00000442833.2
ENST00000280560.8
ENST00000540285.1
ENST00000346530.5
ABCB9
ATP-binding cassette, sub-family B (MDR/TAP), member 9
chr1_-_36615051 0.07 ENST00000373163.1
TRAPPC3
trafficking protein particle complex 3
chr9_+_132934835 0.06 ENST00000372398.3
NCS1
neuronal calcium sensor 1
chr16_+_19729586 0.06 ENST00000564186.1
ENST00000541926.1
ENST00000433597.2
IQCK
IQ motif containing K
chr14_-_76447336 0.06 ENST00000556285.1
TGFB3
transforming growth factor, beta 3
chr6_+_151815143 0.05 ENST00000239374.7
ENST00000367290.5
CCDC170
coiled-coil domain containing 170
chr10_-_112678976 0.05 ENST00000448814.1
BBIP1
BBSome interacting protein 1
chr22_+_29702572 0.05 ENST00000407647.2
ENST00000416823.1
ENST00000428622.1
GAS2L1
growth arrest-specific 2 like 1
chr17_+_18163848 0.05 ENST00000323019.4
ENST00000578174.1
ENST00000395704.4
ENST00000395703.4
ENST00000578621.1
ENST00000579341.1
MIEF2
mitochondrial elongation factor 2
chr15_-_69113218 0.05 ENST00000560303.1
ENST00000465139.2
ANP32A
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr19_+_13135731 0.04 ENST00000587260.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr1_+_113009163 0.04 ENST00000256640.5
WNT2B
wingless-type MMTV integration site family, member 2B
chr12_-_50298000 0.03 ENST00000550635.2
FAIM2
Fas apoptotic inhibitory molecule 2
chr1_+_16370271 0.03 ENST00000375679.4
CLCNKB
chloride channel, voltage-sensitive Kb
chr9_+_100069933 0.02 ENST00000529487.1
CCDC180
coiled-coil domain containing 180
chr11_-_72070206 0.01 ENST00000544382.1
CLPB
ClpB caseinolytic peptidase B homolog (E. coli)
chr17_-_46716647 0.01 ENST00000608940.1
RP11-357H14.17
RP11-357H14.17

Network of associatons between targets according to the STRING database.

First level regulatory network of ZKSCAN1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.5 1.4 GO:0034552 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.4 1.1 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.3 3.6 GO:0018377 protein myristoylation(GO:0018377)
0.3 2.2 GO:0046208 spermine catabolic process(GO:0046208)
0.2 1.6 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.2 2.4 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.2 0.6 GO:0051795 positive regulation of catagen(GO:0051795)
0.2 1.3 GO:0070945 antimicrobial peptide production(GO:0002775) antibacterial peptide production(GO:0002778) neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.2 2.3 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.2 1.7 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 0.9 GO:0098886 modification of dendritic spine(GO:0098886)
0.1 1.5 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 1.4 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.1 0.4 GO:0060298 regulation of vascular permeability involved in acute inflammatory response(GO:0002528) sarcomerogenesis(GO:0048769) positive regulation of sarcomere organization(GO:0060298)
0.1 0.5 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 0.5 GO:0014028 notochord formation(GO:0014028)
0.1 1.7 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.1 0.3 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.1 0.3 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.1 1.0 GO:1902913 positive regulation of melanocyte differentiation(GO:0045636) positive regulation of neuroepithelial cell differentiation(GO:1902913)
0.1 0.7 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.6 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 2.3 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.1 GO:0044691 tooth eruption(GO:0044691)
0.0 0.9 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.0 0.1 GO:0042704 uterine wall breakdown(GO:0042704)
0.0 0.2 GO:0009098 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.0 0.3 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.5 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.4 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.3 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.2 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.0 0.2 GO:0033210 leptin-mediated signaling pathway(GO:0033210)
0.0 0.2 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.0 0.5 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.1 GO:0060994 regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994)
0.0 0.3 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 2.5 GO:0002062 chondrocyte differentiation(GO:0002062)
0.0 0.3 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.3 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.2 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.0 0.3 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.1 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.0 0.3 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.3 GO:0036315 cellular response to sterol(GO:0036315)
0.0 0.2 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.9 GO:0016574 histone ubiquitination(GO:0016574)
0.0 0.5 GO:0043029 T cell homeostasis(GO:0043029)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0097444 spine apparatus(GO:0097444)
0.2 1.1 GO:0090661 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.1 1.6 GO:0097342 ripoptosome(GO:0097342)
0.1 2.2 GO:0031143 pseudopodium(GO:0031143)
0.1 0.5 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.9 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.5 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.9 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 0.7 GO:0001891 phagocytic cup(GO:0001891)
0.0 3.7 GO:0005604 basement membrane(GO:0005604)
0.0 0.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 2.1 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.6 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 1.4 GO:0045178 basal part of cell(GO:0045178)
0.0 0.3 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.6 GO:0016592 mediator complex(GO:0016592)
0.0 2.3 GO:0031901 early endosome membrane(GO:0031901)
0.0 1.2 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.2 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0052894 norspermine:oxygen oxidoreductase activity(GO:0052894) N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity(GO:0052895)
0.6 1.7 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.3 3.6 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.2 2.3 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.1 1.6 GO:0035877 death effector domain binding(GO:0035877)
0.1 0.5 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.1 0.5 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 1.1 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 0.3 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.1 0.5 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.1 0.2 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.1 0.9 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.1 3.1 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 6.5 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 1.4 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 0.3 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 0.5 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.3 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 1.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.3 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 2.5 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 2.3 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.4 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.2 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.3 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.3 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.3 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 1.3 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.3 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 1.6 GO:0005179 hormone activity(GO:0005179)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.3 GO:0031005 filamin binding(GO:0031005)
0.0 1.3 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.3 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.3 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:0031014 troponin T binding(GO:0031014)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.5 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 2.3 PID BARD1 PATHWAY BARD1 signaling events
0.0 1.9 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 1.6 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 1.3 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.4 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.7 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.3 PID AP1 PATHWAY AP-1 transcription factor network
0.0 2.5 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 3.0 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 2.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 1.6 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 2.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 2.2 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 1.7 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 4.4 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 2.3 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 2.5 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.7 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.7 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.3 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)