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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)
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Results for ZKSCAN1
Z-value: 2.44
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Transcription factors associated with ZKSCAN1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ZKSCAN1 | hg19_v2_chr7_+_99613195_99613206 | -0.98 | 1.8e-02 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr20_-_62199427 Show fit | 4.83 |
ENST00000427522.2
|
helicase with zinc finger 2, transcriptional coactivator |
|
| chr19_+_10196781 Show fit | 3.00 |
ENST00000253110.11
|
chromosome 19 open reading frame 66 |
|
| chr12_+_113416265 Show fit | 2.69 |
ENST00000449768.2
|
2'-5'-oligoadenylate synthetase 2, 69/71kDa |
|
| chrX_+_150866779 Show fit | 2.50 |
ENST00000370353.3
|
proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane) |
|
| chr5_+_135394840 Show fit | 2.48 |
ENST00000503087.1
|
transforming growth factor, beta-induced, 68kDa |
|
| chr20_-_48770244 Show fit | 2.40 |
ENST00000371650.5
ENST00000371652.4 ENST00000557021.1 |
transmembrane protein 189 |
|
| chr20_-_56265680 Show fit | 2.34 |
ENST00000414037.1
|
prostate transmembrane protein, androgen induced 1 |
|
| chr22_+_21921994 Show fit | 2.30 |
ENST00000545681.1
|
ubiquitin-conjugating enzyme E2L 3 |
|
| chr10_+_106113515 Show fit | 2.27 |
ENST00000369704.3
ENST00000312902.5 |
coiled-coil domain containing 147 |
|
| chr20_+_4152356 Show fit | 2.18 |
ENST00000379460.2
|
spermine oxidase |
Network of associatons between targets according to the STRING database.
First level regulatory network of ZKSCAN1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 3.6 | GO:0018377 | protein myristoylation(GO:0018377) |
| 0.0 | 2.5 | GO:0002062 | chondrocyte differentiation(GO:0002062) |
| 0.2 | 2.4 | GO:0060753 | regulation of mast cell chemotaxis(GO:0060753) |
| 0.2 | 2.3 | GO:0010991 | negative regulation of SMAD protein complex assembly(GO:0010991) |
| 0.0 | 2.3 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 0.7 | 2.2 | GO:1902396 | protein localization to bicellular tight junction(GO:1902396) |
| 0.3 | 2.2 | GO:0046208 | spermine catabolic process(GO:0046208) |
| 0.2 | 1.7 | GO:0051045 | negative regulation of membrane protein ectodomain proteolysis(GO:0051045) |
| 0.1 | 1.7 | GO:0006704 | glucocorticoid biosynthetic process(GO:0006704) |
| 0.2 | 1.6 | GO:0097527 | necroptotic signaling pathway(GO:0097527) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.7 | GO:0005604 | basement membrane(GO:0005604) |
| 0.0 | 2.3 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.1 | 2.2 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.0 | 2.1 | GO:0030670 | phagocytic vesicle membrane(GO:0030670) |
| 0.1 | 1.6 | GO:0097342 | ripoptosome(GO:0097342) |
| 0.0 | 1.4 | GO:0045178 | basal part of cell(GO:0045178) |
| 0.0 | 1.2 | GO:0035580 | specific granule lumen(GO:0035580) |
| 0.2 | 1.1 | GO:0090661 | box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661) |
| 0.3 | 0.9 | GO:0097444 | spine apparatus(GO:0097444) |
| 0.0 | 0.9 | GO:0035102 | PRC1 complex(GO:0035102) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 6.5 | GO:0030374 | ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374) |
| 0.3 | 3.6 | GO:0001730 | 2'-5'-oligoadenylate synthetase activity(GO:0001730) |
| 0.1 | 3.1 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
| 0.0 | 2.5 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.2 | 2.3 | GO:0097027 | ubiquitin-protein transferase activator activity(GO:0097027) |
| 0.0 | 2.3 | GO:0070412 | R-SMAD binding(GO:0070412) |
| 0.7 | 2.2 | GO:0052894 | norspermine:oxygen oxidoreductase activity(GO:0052894) N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity(GO:0052895) |
| 0.6 | 1.7 | GO:0003845 | 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845) |
| 0.1 | 1.6 | GO:0035877 | death effector domain binding(GO:0035877) |
| 0.0 | 1.6 | GO:0005179 | hormone activity(GO:0005179) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.0 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.0 | 2.5 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 0.0 | 2.5 | PID PDGFRB PATHWAY | PDGFR-beta signaling pathway |
| 0.0 | 2.3 | PID BARD1 PATHWAY | BARD1 signaling events |
| 0.0 | 1.9 | PID IL8 CXCR2 PATHWAY | IL8- and CXCR2-mediated signaling events |
| 0.0 | 1.6 | ST TUMOR NECROSIS FACTOR PATHWAY | Tumor Necrosis Factor Pathway. |
| 0.0 | 1.3 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.0 | 1.3 | PID AP1 PATHWAY | AP-1 transcription factor network |
| 0.0 | 0.7 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.0 | 0.4 | PID S1P S1P4 PATHWAY | S1P4 pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.4 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.0 | 2.5 | REACTOME AMYLOIDS | Genes involved in Amyloids |
| 0.0 | 2.4 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.1 | 2.3 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.0 | 2.3 | REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 0.1 | 2.2 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
| 0.0 | 2.2 | REACTOME NEPHRIN INTERACTIONS | Genes involved in Nephrin interactions |
| 0.0 | 1.7 | REACTOME STEROID HORMONES | Genes involved in Steroid hormones |
| 0.1 | 1.6 | REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 | Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 |
| 0.0 | 0.7 | REACTOME CRMPS IN SEMA3A SIGNALING | Genes involved in CRMPs in Sema3A signaling |