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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)
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Results for VENTX
Z-value: 1.51
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Transcription factors associated with VENTX
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| VENTX | hg19_v2_chr10_+_135050908_135050908 | 0.89 | 1.1e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr9_+_67968793 Show fit | 1.86 |
ENST00000417488.1
|
Protein LOC644249 |
|
| chr4_-_155511887 Show fit | 1.70 |
ENST00000302053.3
ENST00000403106.3 |
fibrinogen alpha chain |
|
| chr8_+_107738240 Show fit | 1.36 |
ENST00000449762.2
ENST00000297447.6 |
oxidation resistance 1 |
|
| chr10_-_33405600 Show fit | 1.26 |
ENST00000414308.1
|
RP11-342D11.3 |
|
| chr13_+_110958124 Show fit | 1.23 |
ENST00000400163.2
|
collagen, type IV, alpha 2 |
|
| chr13_-_67802549 Show fit | 1.09 |
ENST00000328454.5
ENST00000377865.2 |
protocadherin 9 |
|
| chr6_+_43968306 Show fit | 1.04 |
ENST00000442114.2
ENST00000336600.5 ENST00000439969.2 |
chromosome 6 open reading frame 223 |
|
| chr5_-_79950775 Show fit | 1.04 |
ENST00000439211.2
|
dihydrofolate reductase |
|
| chr4_+_119200215 Show fit | 1.01 |
ENST00000602573.1
|
small nucleolar RNA host gene 8 (non-protein coding) |
|
| chr18_+_29171689 Show fit | 0.96 |
ENST00000237014.3
|
transthyretin |
Network of associatons between targets according to the STRING database.
First level regulatory network of VENTX
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.8 | GO:0071447 | cellular response to hydroperoxide(GO:0071447) |
| 0.1 | 1.7 | GO:0043152 | induction of bacterial agglutination(GO:0043152) |
| 0.0 | 1.2 | GO:0038063 | collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) |
| 0.0 | 1.2 | GO:0002230 | positive regulation of defense response to virus by host(GO:0002230) |
| 0.3 | 1.0 | GO:0046452 | dihydrofolate metabolic process(GO:0046452) |
| 0.1 | 1.0 | GO:0070327 | thyroid hormone transport(GO:0070327) |
| 0.0 | 1.0 | GO:0040015 | negative regulation of multicellular organism growth(GO:0040015) |
| 0.0 | 0.9 | GO:0070886 | positive regulation of calcineurin-NFAT signaling cascade(GO:0070886) |
| 0.0 | 0.9 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
| 0.0 | 0.9 | GO:0045736 | negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.7 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.0 | 1.4 | GO:0016328 | lateral plasma membrane(GO:0016328) |
| 0.0 | 1.4 | GO:0035578 | azurophil granule lumen(GO:0035578) |
| 0.1 | 1.2 | GO:0005587 | collagen type IV trimer(GO:0005587) |
| 0.0 | 0.7 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.1 | 0.6 | GO:0048237 | rough endoplasmic reticulum lumen(GO:0048237) |
| 0.0 | 0.6 | GO:0000145 | exocyst(GO:0000145) |
| 0.0 | 0.5 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
| 0.1 | 0.4 | GO:0035101 | FACT complex(GO:0035101) |
| 0.1 | 0.4 | GO:0042720 | mitochondrial inner membrane peptidase complex(GO:0042720) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.4 | GO:0038132 | neuregulin binding(GO:0038132) |
| 0.0 | 1.4 | GO:0005179 | hormone activity(GO:0005179) |
| 0.0 | 1.2 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.1 | 1.1 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
| 0.2 | 1.0 | GO:0051870 | methotrexate binding(GO:0051870) |
| 0.1 | 1.0 | GO:0070324 | thyroid hormone binding(GO:0070324) |
| 0.0 | 0.9 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 0.0 | 0.7 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 0.0 | 0.7 | GO:0001671 | ATPase activator activity(GO:0001671) |
| 0.1 | 0.6 | GO:0031708 | endothelin B receptor binding(GO:0031708) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.0 | PID EPHRINB REV PATHWAY | Ephrin B reverse signaling |
| 0.0 | 1.7 | PID E2F PATHWAY | E2F transcription factor network |
| 0.0 | 1.2 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.0 | 1.2 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 0.9 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
| 0.0 | 0.3 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.7 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 0.0 | 1.6 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
| 0.0 | 1.2 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.0 | 1.0 | REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION | Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation |
| 0.0 | 1.0 | REACTOME AMYLOIDS | Genes involved in Amyloids |
| 0.0 | 0.9 | REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
| 0.0 | 0.9 | REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.0 | 0.7 | REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP | Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) |
| 0.0 | 0.6 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.0 | 0.3 | REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |