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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)
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Results for UUGGCAA
Z-value: 1.36
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miRNA associated with seed UUGGCAA
| Name | miRBASE accession |
|---|---|
|
hsa-miR-182-5p
|
MIMAT0000259 |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr9_-_4741255 Show fit | 0.97 |
ENST00000381809.3
|
adenylate kinase 3 |
|
| chr9_+_91003271 Show fit | 0.95 |
ENST00000375859.3
ENST00000541629.1 |
spindlin 1 |
|
| chr2_-_44588893 Show fit | 0.82 |
ENST00000409272.1
ENST00000410081.1 ENST00000541738.1 |
prolyl endopeptidase-like |
|
| chr6_-_109703663 Show fit | 0.76 |
ENST00000368961.5
|
CD164 molecule, sialomucin |
|
| chr8_-_103876965 Show fit | 0.75 |
ENST00000337198.5
|
antizyme inhibitor 1 |
|
| chr3_+_187930719 Show fit | 0.72 |
ENST00000312675.4
|
LIM domain containing preferred translocation partner in lipoma |
|
| chr3_-_161090660 Show fit | 0.71 |
ENST00000359175.4
|
serine palmitoyltransferase, small subunit B |
|
| chr7_-_66460563 Show fit | 0.71 |
ENST00000246868.2
|
Shwachman-Bodian-Diamond syndrome |
|
| chr15_-_51058005 Show fit | 0.70 |
ENST00000261854.5
|
signal peptide peptidase like 2A |
|
| chr2_+_103236004 Show fit | 0.69 |
ENST00000233969.2
|
solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
Network of associatons between targets according to the STRING database.
First level regulatory network of UUGGCAA
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 1.0 | GO:0046041 | ITP metabolic process(GO:0046041) |
| 0.1 | 1.0 | GO:0010606 | positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606) |
| 0.0 | 1.0 | GO:0051058 | negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058) |
| 0.0 | 0.9 | GO:0009303 | rRNA transcription(GO:0009303) |
| 0.2 | 0.8 | GO:1902269 | positive regulation of polyamine transmembrane transport(GO:1902269) |
| 0.1 | 0.7 | GO:0048539 | bone marrow development(GO:0048539) |
| 0.1 | 0.7 | GO:1904220 | regulation of serine C-palmitoyltransferase activity(GO:1904220) |
| 0.1 | 0.7 | GO:0010216 | maintenance of DNA methylation(GO:0010216) C-5 methylation of cytosine(GO:0090116) |
| 0.1 | 0.7 | GO:0061088 | regulation of sequestering of zinc ion(GO:0061088) |
| 0.0 | 0.7 | GO:1990118 | sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.5 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.0 | 1.3 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.0 | 1.1 | GO:0070822 | Sin3-type complex(GO:0070822) |
| 0.0 | 0.9 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
| 0.0 | 0.8 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.2 | 0.7 | GO:0071458 | integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) |
| 0.1 | 0.7 | GO:0031211 | serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211) |
| 0.0 | 0.7 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.0 | 0.7 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
| 0.0 | 0.7 | GO:1990752 | microtubule end(GO:1990752) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 1.0 | GO:0046899 | nucleoside triphosphate adenylate kinase activity(GO:0046899) |
| 0.1 | 0.9 | GO:0016813 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813) |
| 0.0 | 0.9 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 0.0 | 0.9 | GO:0005158 | insulin receptor binding(GO:0005158) |
| 0.1 | 0.8 | GO:0042978 | ornithine decarboxylase activator activity(GO:0042978) |
| 0.0 | 0.8 | GO:0070008 | serine-type exopeptidase activity(GO:0070008) |
| 0.1 | 0.7 | GO:0042500 | aspartic endopeptidase activity, intramembrane cleaving(GO:0042500) |
| 0.1 | 0.7 | GO:0004758 | serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454) |
| 0.1 | 0.7 | GO:0003886 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) |
| 0.0 | 0.7 | GO:0015386 | potassium:proton antiporter activity(GO:0015386) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.0 | PID THROMBIN PAR4 PATHWAY | PAR4-mediated thrombin signaling events |
| 0.0 | 0.9 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.0 | 0.9 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.0 | 0.6 | SA G2 AND M PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 0.0 | 0.4 | PID S1P META PATHWAY | Sphingosine 1-phosphate (S1P) pathway |
| 0.0 | 0.4 | PID NFKAPPAB ATYPICAL PATHWAY | Atypical NF-kappaB pathway |
| 0.0 | 0.3 | SA B CELL RECEPTOR COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
| 0.0 | 0.3 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.5 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.0 | 0.9 | REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
| 0.0 | 0.8 | REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC | Genes involved in Regulation of ornithine decarboxylase (ODC) |
| 0.0 | 0.8 | REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION | Genes involved in Transport to the Golgi and subsequent modification |
| 0.0 | 0.7 | REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR | Genes involved in Thromboxane signalling through TP receptor |
| 0.0 | 0.6 | REACTOME RAF MAP KINASE CASCADE | Genes involved in RAF/MAP kinase cascade |
| 0.0 | 0.6 | REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 0.0 | 0.5 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
| 0.0 | 0.5 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.0 | 0.5 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |