Project
A549 cells infected with RSV Analysis Results (GEO series: GSE147507)
Navigation
Downloads
Results for TLX1_NFIC
Z-value: 2.01
Motif logo
Transcription factors associated with TLX1_NFIC
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| NFIC | hg19_v2_chr19_+_3359561_3359681 | -0.75 | 2.5e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of TLX1_NFIC
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 4.5 | GO:0042832 | defense response to protozoan(GO:0042832) |
| 0.3 | 3.3 | GO:0098795 | mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795) |
| 0.0 | 3.2 | GO:0050919 | negative chemotaxis(GO:0050919) |
| 0.5 | 2.7 | GO:0000738 | DNA catabolic process, exonucleolytic(GO:0000738) |
| 0.8 | 2.5 | GO:0046521 | sphingoid catabolic process(GO:0046521) |
| 0.1 | 2.4 | GO:0031639 | plasminogen activation(GO:0031639) |
| 0.2 | 2.3 | GO:1902363 | regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846) |
| 0.1 | 2.1 | GO:0048569 | post-embryonic organ development(GO:0048569) |
| 0.0 | 1.8 | GO:0060445 | branching involved in salivary gland morphogenesis(GO:0060445) |
| 0.1 | 1.7 | GO:0002544 | chronic inflammatory response(GO:0002544) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.5 | GO:0097517 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
| 0.0 | 3.1 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
| 0.0 | 2.8 | GO:0015030 | Cajal body(GO:0015030) |
| 0.2 | 2.3 | GO:0055028 | cortical microtubule(GO:0055028) |
| 0.3 | 1.7 | GO:0043260 | laminin-11 complex(GO:0043260) |
| 0.0 | 1.5 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.0 | 1.2 | GO:1904724 | tertiary granule lumen(GO:1904724) |
| 0.3 | 1.1 | GO:0071062 | alphav-beta3 integrin-vitronectin complex(GO:0071062) |
| 0.1 | 1.1 | GO:0005610 | laminin-5 complex(GO:0005610) |
| 0.0 | 1.1 | GO:0030122 | AP-2 adaptor complex(GO:0030122) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.9 | GO:0005178 | integrin binding(GO:0005178) |
| 0.0 | 3.3 | GO:0008083 | growth factor activity(GO:0008083) |
| 0.1 | 3.2 | GO:0038191 | neuropilin binding(GO:0038191) |
| 0.0 | 3.0 | GO:0004386 | helicase activity(GO:0004386) |
| 0.9 | 2.7 | GO:0008859 | exoribonuclease II activity(GO:0008859) |
| 0.4 | 2.5 | GO:0017050 | sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050) |
| 0.0 | 2.4 | GO:0008201 | heparin binding(GO:0008201) |
| 0.1 | 2.3 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
| 0.0 | 2.1 | GO:0051219 | phosphoprotein binding(GO:0051219) |
| 0.2 | 1.7 | GO:0004459 | L-lactate dehydrogenase activity(GO:0004459) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.2 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 0.0 | 4.2 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.1 | 3.7 | PID S1P S1P1 PATHWAY | S1P1 pathway |
| 0.1 | 2.8 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.0 | 1.7 | PID THROMBIN PAR1 PATHWAY | PAR1-mediated thrombin signaling events |
| 0.0 | 1.6 | PID P75 NTR PATHWAY | p75(NTR)-mediated signaling |
| 0.0 | 1.5 | PID IL27 PATHWAY | IL27-mediated signaling events |
| 0.0 | 1.5 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.0 | 1.5 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.0 | 1.1 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 5.6 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.1 | 3.4 | REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION | Genes involved in Pre-NOTCH Transcription and Translation |
| 0.0 | 2.7 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.0 | 2.5 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.1 | 2.3 | REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES | Genes involved in Recruitment of NuMA to mitotic centrosomes |
| 0.0 | 1.7 | REACTOME PYRUVATE METABOLISM | Genes involved in Pyruvate metabolism |
| 0.0 | 1.7 | REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE | Genes involved in Cell death signalling via NRAGE, NRIF and NADE |
| 0.0 | 1.1 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.0 | 0.7 | REACTOME IL 6 SIGNALING | Genes involved in Interleukin-6 signaling |
| 0.0 | 0.7 | REACTOME INITIAL TRIGGERING OF COMPLEMENT | Genes involved in Initial triggering of complement |