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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for TFEC_MITF_ARNTL_BHLHE41

Z-value: 0.94

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Transcription factors associated with TFEC_MITF_ARNTL_BHLHE41

Gene Symbol Gene ID Gene Info
ENSG00000105967.11 transcription factor EC
ENSG00000187098.10 melanocyte inducing transcription factor
ENSG00000133794.13 aryl hydrocarbon receptor nuclear translocator like
ENSG00000123095.5 basic helix-loop-helix family member e41

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MITFhg19_v2_chr3_+_69985792_69985874-0.955.3e-02Click!
BHLHE41hg19_v2_chr12_-_26278030_26278060-0.524.8e-01Click!
TFEChg19_v2_chr7_-_115670792_1156707980.336.7e-01Click!
ARNTLhg19_v2_chr11_+_13299186_13299432-0.297.1e-01Click!

Activity profile of TFEC_MITF_ARNTL_BHLHE41 motif

Sorted Z-values of TFEC_MITF_ARNTL_BHLHE41 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_58145889 1.76 ENST00000547853.1
cyclin-dependent kinase 4
chr17_-_6915616 1.06 ENST00000575889.1
Uncharacterized protein
chr13_+_113951607 0.99 ENST00000397181.3
lysosomal-associated membrane protein 1
chr17_-_7137582 0.91 ENST00000575756.1
ENST00000575458.1
dishevelled segment polarity protein 2
chr12_+_123849462 0.90 ENST00000543072.1
hsa-mir-8072
chr1_-_42921915 0.90 ENST00000372565.3
ENST00000433602.2
zinc finger, MYND-type containing 12
chr12_+_56109926 0.84 ENST00000547076.1
biogenesis of lysosomal organelles complex-1, subunit 1
chrX_-_100662881 0.77 ENST00000218516.3
galactosidase, alpha
chr17_-_7137857 0.75 ENST00000005340.5
dishevelled segment polarity protein 2
chr12_-_58146048 0.74 ENST00000547281.1
ENST00000546489.1
ENST00000552388.1
ENST00000540325.1
ENST00000312990.6
cyclin-dependent kinase 4
chr10_-_46089939 0.73 ENST00000453980.3
membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
chr19_+_49458107 0.71 ENST00000539787.1
ENST00000345358.7
ENST00000391871.3
ENST00000415969.2
ENST00000354470.3
ENST00000506183.1
ENST00000293288.8
BCL2-associated X protein
chr12_+_56110247 0.69 ENST00000551926.1
biogenesis of lysosomal organelles complex-1, subunit 1
chr2_-_220042825 0.67 ENST00000409789.1
cyclin Pas1/PHO80 domain containing 1
chr14_-_81687575 0.65 ENST00000434192.2
general transcription factor IIA, 1, 19/37kDa
chr12_-_58146128 0.60 ENST00000551800.1
ENST00000549606.1
ENST00000257904.6
cyclin-dependent kinase 4
chr1_+_11866270 0.60 ENST00000376497.3
ENST00000376487.3
ENST00000376496.3
chloride channel, voltage-sensitive 6
chr12_+_56110315 0.59 ENST00000548556.1
biogenesis of lysosomal organelles complex-1, subunit 1
chr19_+_4402659 0.56 ENST00000301280.5
ENST00000585854.1
chromatin assembly factor 1, subunit A (p150)
chr16_+_28985542 0.50 ENST00000567771.1
ENST00000568388.1
spinster homolog 1 (Drosophila)
chrX_-_118699325 0.50 ENST00000320339.4
ENST00000371594.4
ENST00000536133.1
chromosome X open reading frame 56
chr1_-_166845515 0.49 ENST00000367874.4
transcriptional adaptor 1
chr1_-_154193009 0.49 ENST00000368518.1
ENST00000368519.1
ENST00000368521.5
chromosome 1 open reading frame 43
chr7_-_27205136 0.49 ENST00000396345.1
ENST00000343483.6
homeobox A9
chr19_-_10426663 0.49 ENST00000541276.1
ENST00000393708.3
ENST00000494368.1
ferredoxin 1-like
chr1_+_92414952 0.48 ENST00000449584.1
ENST00000427104.1
ENST00000355011.3
ENST00000448194.1
ENST00000426141.1
ENST00000450792.1
ENST00000548992.1
ENST00000552654.1
ENST00000457265.1
bromodomain, testis-specific
chr1_-_154193091 0.48 ENST00000362076.4
ENST00000350592.3
ENST00000368516.1
chromosome 1 open reading frame 43
chr19_+_10764937 0.47 ENST00000449870.1
ENST00000318511.3
ENST00000420083.1
interleukin enhancer binding factor 3, 90kDa
chr16_-_28503357 0.47 ENST00000333496.9
ENST00000561505.1
ENST00000567963.1
ENST00000354630.5
ENST00000355477.5
ENST00000357076.5
ENST00000565688.1
ENST00000359984.7
ceroid-lipofuscinosis, neuronal 3
chr2_+_220042933 0.46 ENST00000430297.2
family with sequence similarity 134, member A
chr22_-_39268308 0.46 ENST00000407418.3
chromobox homolog 6
chr16_-_28503327 0.45 ENST00000535392.1
ENST00000395653.4
ceroid-lipofuscinosis, neuronal 3
chr6_-_33385823 0.45 ENST00000494751.1
ENST00000374496.3
cutA divalent cation tolerance homolog (E. coli)
chr19_-_40854417 0.44 ENST00000582006.1
ENST00000582783.1
chromosome 19 open reading frame 47
chr1_-_155211065 0.44 ENST00000427500.3
glucosidase, beta, acid
chr1_-_11866034 0.44 ENST00000376590.3
methylenetetrahydrofolate reductase (NAD(P)H)
chr1_-_155211017 0.43 ENST00000536770.1
ENST00000368373.3
glucosidase, beta, acid
chr2_+_27309605 0.43 ENST00000260599.6
ENST00000260598.5
ENST00000429697.1
ketohexokinase (fructokinase)
chr3_+_113465866 0.42 ENST00000273398.3
ENST00000538620.1
ENST00000496747.1
ENST00000475322.1
ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
chr12_+_56109810 0.42 ENST00000550412.1
ENST00000257899.2
ENST00000548925.1
ENST00000549147.1
Uncharacterized protein
biogenesis of lysosomal organelles complex-1, subunit 1
chr17_+_18218587 0.41 ENST00000406438.3
Smith-Magenis syndrome chromosome region, candidate 8
chr16_-_28503080 0.41 ENST00000565316.1
ENST00000565778.1
ENST00000357857.9
ENST00000568558.1
ENST00000357806.7
ceroid-lipofuscinosis, neuronal 3
chr17_-_48450265 0.41 ENST00000507088.1
mitochondrial ribosomal protein L27
chr19_+_10812108 0.40 ENST00000250237.5
ENST00000592254.1
queuine tRNA-ribosyltransferase 1
chr17_-_48450534 0.40 ENST00000503633.1
ENST00000442592.3
ENST00000225969.4
mitochondrial ribosomal protein L27
chr12_-_90103077 0.40 ENST00000551310.1
ATPase, Ca++ transporting, plasma membrane 1
chr15_+_44084503 0.40 ENST00000409960.2
ENST00000409646.1
ENST00000594896.1
ENST00000339624.5
ENST00000409291.1
ENST00000402131.1
ENST00000403425.1
ENST00000430901.1
small EDRK-rich factor 2
chr12_-_122751002 0.39 ENST00000267199.4
vacuolar protein sorting 33 homolog A (S. cerevisiae)
chr7_+_100464760 0.39 ENST00000200457.4
thyroid hormone receptor interactor 6
chr7_+_99746514 0.39 ENST00000341942.5
ENST00000441173.1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 4
chr19_+_41305406 0.37 ENST00000406058.2
ENST00000593726.1
egl-9 family hypoxia-inducible factor 2
chr6_+_160390102 0.37 ENST00000356956.1
insulin-like growth factor 2 receptor
chr17_-_6915646 0.36 ENST00000574377.1
ENST00000399541.2
ENST00000399540.2
ENST00000575727.1
ENST00000573939.1
Uncharacterized protein
chr12_+_51633061 0.35 ENST00000551313.1
DAZ associated protein 2
chr13_+_113951532 0.35 ENST00000332556.4
lysosomal-associated membrane protein 1
chr9_-_100684845 0.35 ENST00000375119.3
chromosome 9 open reading frame 156
chr22_-_36903069 0.35 ENST00000216187.6
ENST00000423980.1
FAD-dependent oxidoreductase domain containing 2
chr17_+_1627834 0.35 ENST00000419248.1
ENST00000418841.1
WD repeat domain 81
chr15_+_44084040 0.35 ENST00000249786.4
small EDRK-rich factor 2
chr19_-_10764509 0.35 ENST00000591501.1
ILF3 antisense RNA 1 (head to head)
chr15_+_75628232 0.34 ENST00000267935.8
ENST00000567195.1
COMM domain containing 4
chr15_+_75628419 0.34 ENST00000567377.1
ENST00000562789.1
ENST00000568301.1
COMM domain containing 4
chr6_-_36953833 0.34 ENST00000538808.1
ENST00000460219.1
ENST00000373616.5
ENST00000373627.5
mitochondrial carrier 1
chr18_-_2982869 0.33 ENST00000584915.1
lipin 2
chr5_-_110074603 0.33 ENST00000515278.2
transmembrane protein 232
chr12_+_54426637 0.33 ENST00000312492.2
homeobox C5
chr20_+_37590942 0.33 ENST00000373325.2
ENST00000252011.3
ENST00000373323.4
DEAH (Asp-Glu-Ala-His) box polypeptide 35
chr9_+_131709966 0.32 ENST00000372577.2
nucleoporin 188kDa
chr16_-_5083589 0.32 ENST00000563578.1
ENST00000562346.2
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr5_-_176730676 0.31 ENST00000393611.2
ENST00000303251.6
ENST00000303270.6
RAB24, member RAS oncogene family
chr5_-_150138246 0.31 ENST00000518015.1
dynactin 4 (p62)
chr16_+_88923494 0.31 ENST00000567895.1
ENST00000301021.3
ENST00000565504.1
ENST00000567312.1
ENST00000568583.1
ENST00000561840.1
trafficking protein particle complex 2-like
chr10_-_25305011 0.31 ENST00000331161.4
ENST00000376363.1
enkurin, TRPC channel interacting protein
chr19_+_5681153 0.31 ENST00000579559.1
ENST00000577222.1
hydroxysteroid (11-beta) dehydrogenase 1-like
ribosomal protein L36
chr1_+_22778337 0.31 ENST00000404138.1
ENST00000400239.2
ENST00000375647.4
ENST00000374651.4
zinc finger and BTB domain containing 40
chr19_+_41305085 0.31 ENST00000303961.4
egl-9 family hypoxia-inducible factor 2
chr22_-_39268192 0.30 ENST00000216083.6
chromobox homolog 6
chr11_+_118938485 0.30 ENST00000300793.6
vacuolar protein sorting 11 homolog (S. cerevisiae)
chr22_-_42342692 0.29 ENST00000404067.1
ENST00000402338.1
centromere protein M
chr3_+_184032419 0.29 ENST00000352767.3
ENST00000427141.2
eukaryotic translation initiation factor 4 gamma, 1
chrX_+_102883887 0.29 ENST00000372625.3
ENST00000372624.3
transcription elongation factor A (SII)-like 1
chr19_+_7587555 0.29 ENST00000601003.1
mucolipin 1
chr2_-_220083671 0.29 ENST00000439002.2
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr19_+_41305330 0.29 ENST00000593972.1
egl-9 family hypoxia-inducible factor 2
chr3_-_4508925 0.28 ENST00000534863.1
ENST00000383843.5
ENST00000458465.2
ENST00000405420.2
ENST00000272902.5
sulfatase modifying factor 1
chr22_-_39096981 0.28 ENST00000427389.1
Josephin domain containing 1
chr10_+_51827648 0.28 ENST00000351071.6
ENST00000314664.7
ENST00000282633.5
family with sequence similarity 21, member A
chr19_-_12833361 0.28 ENST00000592287.1
transportin 2
chr6_+_139349903 0.27 ENST00000461027.1
ABRA C-terminal like
chr11_+_18344106 0.27 ENST00000534641.1
ENST00000525831.1
ENST00000265963.4
general transcription factor IIH, polypeptide 1, 62kDa
chr17_+_46018872 0.27 ENST00000583599.1
ENST00000434554.2
ENST00000225573.4
ENST00000544840.1
ENST00000534893.1
pyridoxamine 5'-phosphate oxidase
chr17_+_48450575 0.27 ENST00000338165.4
ENST00000393271.2
ENST00000511519.2
essential meiotic structure-specific endonuclease 1
chr3_+_51428704 0.27 ENST00000323686.4
RNA binding motif protein 15B
chr9_-_139137648 0.27 ENST00000358701.5
quiescin Q6 sulfhydryl oxidase 2
chr1_-_52831796 0.27 ENST00000284376.3
ENST00000438831.1
ENST00000371586.2
coiled-coil and C2 domain containing 1B
chr20_+_44519948 0.27 ENST00000354880.5
ENST00000191018.5
cathepsin A
chr1_-_156265438 0.26 ENST00000362007.1
chromosome 1 open reading frame 85
chr16_+_31044413 0.26 ENST00000394998.1
syntaxin 4
chr1_+_44440575 0.26 ENST00000532642.1
ENST00000236067.4
ENST00000471859.2
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr1_+_45477819 0.26 ENST00000246337.4
uroporphyrinogen decarboxylase
chr1_-_154928562 0.26 ENST00000368463.3
ENST00000539880.1
ENST00000542459.1
ENST00000368460.3
ENST00000368465.1
pre-B-cell leukemia homeobox interacting protein 1
chr16_+_5083950 0.26 ENST00000588623.1
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
chr19_+_47634039 0.26 ENST00000597808.1
ENST00000413379.3
ENST00000600706.1
ENST00000540850.1
ENST00000598840.1
ENST00000600753.1
ENST00000270225.7
ENST00000392776.3
SUMO1 activating enzyme subunit 1
chrX_+_100663243 0.26 ENST00000316594.5
heterogeneous nuclear ribonucleoprotein H2 (H')
chrX_-_101397433 0.25 ENST00000372774.3
transcription elongation factor A (SII)-like 6
chr12_+_53645870 0.25 ENST00000329548.4
major facilitator superfamily domain containing 5
chr19_+_10765003 0.25 ENST00000407004.3
ENST00000589998.1
ENST00000589600.1
interleukin enhancer binding factor 3, 90kDa
chr12_+_54332535 0.25 ENST00000243056.3
homeobox C13
chr2_-_220083692 0.25 ENST00000265316.3
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr10_+_99344104 0.25 ENST00000555577.1
ENST00000370649.3
phosphatidylinositol 4-kinase type 2 alpha
Phosphatidylinositol 4-kinase type 2-alpha; Uncharacterized protein
chr20_+_44520009 0.25 ENST00000607482.1
ENST00000372459.2
cathepsin A
chr1_-_154909329 0.25 ENST00000368467.3
phosphomevalonate kinase
chr17_+_7344057 0.25 ENST00000575398.1
ENST00000575082.1
fibroblast growth factor 11
chr11_-_71814276 0.25 ENST00000538404.1
ENST00000535107.1
ENST00000545249.1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
chr19_+_5681011 0.24 ENST00000581893.1
ENST00000411793.2
ENST00000301382.4
ENST00000581773.1
ENST00000423665.2
ENST00000583928.1
ENST00000342970.2
ENST00000422535.2
ENST00000581521.1
ENST00000339423.2
hydroxysteroid (11-beta) dehydrogenase 1-like
chr19_+_8386371 0.24 ENST00000600659.2
ribosomal protein S28
chr19_-_15236562 0.24 ENST00000263383.3
ilvB (bacterial acetolactate synthase)-like
chr5_+_150827143 0.24 ENST00000243389.3
ENST00000517945.1
ENST00000521925.1
solute carrier family 36 (proton/amino acid symporter), member 1
chr15_+_75628394 0.24 ENST00000564815.1
ENST00000338995.6
COMM domain containing 4
chr16_-_70323422 0.24 ENST00000261772.8
alanyl-tRNA synthetase
chr14_-_94443105 0.24 ENST00000555019.1
ankyrin repeat and SOCS box containing 2
chr19_+_12848299 0.23 ENST00000357332.3
arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
chr17_-_30185946 0.23 ENST00000579741.1
coordinator of PRMT5, differentiation stimulator
chr19_-_40854281 0.23 ENST00000392035.2
chromosome 19 open reading frame 47
chr6_-_33385655 0.23 ENST00000440279.3
ENST00000607266.1
cutA divalent cation tolerance homolog (E. coli)
chr19_+_14544099 0.23 ENST00000242783.6
ENST00000586557.1
ENST00000590097.1
protein kinase N1
chr11_+_777562 0.23 ENST00000530083.1
Protein LOC100506518
chr19_-_19739321 0.23 ENST00000588461.1
lysophosphatidic acid receptor 2
chr16_+_9185450 0.23 ENST00000327827.7
chromosome 16 open reading frame 72
chr17_+_73975292 0.23 ENST00000397640.1
ENST00000416485.1
ENST00000588202.1
ENST00000590676.1
ENST00000586891.1
TEN1 CST complex subunit
chr2_+_240323439 0.23 ENST00000428471.1
ENST00000413029.1
Uncharacterized protein
chr19_+_35810164 0.23 ENST00000598537.1
CD22 molecule
chr11_+_126081662 0.22 ENST00000528985.1
ENST00000529731.1
ENST00000360194.4
ENST00000530043.1
family with sequence similarity 118, member B
chr16_-_68269971 0.22 ENST00000565858.1
epithelial splicing regulatory protein 2
chr7_+_100271446 0.22 ENST00000419828.1
ENST00000427895.1
guanine nucleotide binding protein (G protein), beta polypeptide 2
chrX_-_102319092 0.22 ENST00000372728.3
brain expressed, X-linked 1
chr16_+_28986085 0.22 ENST00000565975.1
ENST00000311008.11
ENST00000323081.8
ENST00000334536.8
spinster homolog 1 (Drosophila)
chr16_-_5083917 0.22 ENST00000312251.3
ENST00000381955.3
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr14_-_68283291 0.22 ENST00000555452.1
ENST00000347230.4
zinc finger, FYVE domain containing 26
chr3_+_184032313 0.22 ENST00000392537.2
ENST00000444134.1
ENST00000450424.1
ENST00000421110.1
ENST00000382330.3
ENST00000426123.1
ENST00000350481.5
ENST00000455679.1
ENST00000440448.1
eukaryotic translation initiation factor 4 gamma, 1
chr16_+_29127282 0.22 ENST00000562902.1
RP11-426C22.5
chr14_-_20929624 0.22 ENST00000398020.4
ENST00000250489.4
transmembrane protein 55B
chr19_+_6464502 0.22 ENST00000308243.7
crumbs homolog 3 (Drosophila)
chr16_+_69796209 0.22 ENST00000359154.2
ENST00000561780.1
ENST00000563659.1
ENST00000448661.1
WW domain containing E3 ubiquitin protein ligase 2
chr4_-_100871506 0.21 ENST00000296417.5
H2A histone family, member Z
chr19_+_6464243 0.21 ENST00000600229.1
ENST00000356762.3
crumbs homolog 3 (Drosophila)
chr8_+_98656336 0.21 ENST00000336273.3
metadherin
chr10_-_18948208 0.21 ENST00000607346.1
ARL5B antisense RNA 1
chr4_-_120222076 0.21 ENST00000504110.1
chromosome 4 open reading frame 3
chr1_-_198906528 0.21 ENST00000432296.1
MIR181A1 host gene (non-protein coding)
chr19_+_49990811 0.21 ENST00000391857.4
ENST00000467825.2
ribosomal protein L13a
chr19_-_15236470 0.21 ENST00000533747.1
ENST00000598709.1
ENST00000534378.1
ilvB (bacterial acetolactate synthase)-like
chr22_+_40573921 0.21 ENST00000454349.2
ENST00000335727.9
trinucleotide repeat containing 6B
chr11_-_36310958 0.21 ENST00000532705.1
ENST00000263401.5
ENST00000452374.2
COMM domain containing 9
chr22_-_50700140 0.20 ENST00000215659.8
mitogen-activated protein kinase 12
chr1_+_45477901 0.20 ENST00000434478.1
uroporphyrinogen decarboxylase
chr10_+_46222648 0.20 ENST00000336378.4
ENST00000540872.1
ENST00000537517.1
ENST00000374362.2
ENST00000359860.4
ENST00000420848.1
family with sequence similarity 21, member C
chr16_-_70719925 0.20 ENST00000338779.6
metastasis suppressor 1-like
chr17_+_17876127 0.20 ENST00000582416.1
ENST00000313838.8
ENST00000411504.2
ENST00000581264.1
ENST00000399187.1
ENST00000479684.2
ENST00000584166.1
ENST00000585108.1
ENST00000399182.1
ENST00000579977.1
leucine rich repeat containing 48
chr1_-_11865982 0.20 ENST00000418034.1
methylenetetrahydrofolate reductase (NAD(P)H)
chr17_+_78075361 0.20 ENST00000577106.1
ENST00000390015.3
glucosidase, alpha; acid
chr7_-_99699538 0.20 ENST00000343023.6
ENST00000303887.5
minichromosome maintenance complex component 7
chr15_-_72668805 0.20 ENST00000268097.5
hexosaminidase A (alpha polypeptide)
chr10_-_82049424 0.20 ENST00000372213.3
methionine adenosyltransferase I, alpha
chr1_-_27226928 0.20 ENST00000361720.5
G patch domain containing 3
chr12_+_53400176 0.20 ENST00000551002.1
ENST00000420463.3
ENST00000416762.3
ENST00000549481.1
ENST00000552490.1
eukaryotic translation initiation factor 4B
chr3_+_184032283 0.20 ENST00000346169.2
ENST00000414031.1
eukaryotic translation initiation factor 4 gamma, 1
chr9_-_90589586 0.19 ENST00000325303.8
ENST00000375883.3
cyclin-dependent kinase 20
chr7_+_99775366 0.19 ENST00000394018.2
ENST00000416412.1
stromal antigen 3
chr20_+_2821366 0.19 ENST00000453689.1
ENST00000417508.1
vacuolar protein sorting 16 homolog (S. cerevisiae)
chr16_-_58718611 0.19 ENST00000564100.1
ENST00000570101.1
solute carrier family 38, member 7
chr12_-_2986107 0.19 ENST00000359843.3
ENST00000342628.2
ENST00000361953.3
forkhead box M1
chr14_+_77564701 0.19 ENST00000557115.1
CLOCK-interacting pacemaker
chr9_-_131709858 0.19 ENST00000372586.3
dolichol kinase
chr17_+_42977062 0.19 ENST00000410006.2
ENST00000357776.2
ENST00000410027.1
coiled-coil domain containing 103
chr16_-_67514982 0.19 ENST00000565835.1
ENST00000540149.1
ENST00000290949.3
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
chr9_+_136325149 0.19 ENST00000542192.1
calcium channel flower domain containing 1
chr7_+_116593568 0.19 ENST00000446490.1
suppression of tumorigenicity 7
chr19_-_5719860 0.19 ENST00000590729.1
lon peptidase 1, mitochondrial
chr10_+_52751010 0.19 ENST00000373985.1
protein kinase, cGMP-dependent, type I
chr12_+_54366894 0.19 ENST00000546378.1
ENST00000243082.4
homeobox C11
chr10_+_99258625 0.19 ENST00000370664.3
ubiquitin domain containing 1
chr22_-_42343117 0.18 ENST00000407253.3
ENST00000215980.5
centromere protein M
chr19_-_1237990 0.18 ENST00000382477.2
ENST00000215376.6
ENST00000590083.1
chromosome 19 open reading frame 26
chrX_+_118108571 0.18 ENST00000304778.7
LON peptidase N-terminal domain and ring finger 3
chr2_-_131850951 0.18 ENST00000409185.1
ENST00000389915.3
family with sequence similarity 168, member B
chr17_+_62503073 0.18 ENST00000580188.1
ENST00000581056.1
centrosomal protein 95kDa
chr19_-_5340730 0.18 ENST00000372412.4
ENST00000357368.4
ENST00000262963.6
ENST00000348075.2
ENST00000353284.2
protein tyrosine phosphatase, receptor type, S
chr5_-_1799965 0.18 ENST00000508987.1
mitochondrial ribosomal protein L36
chr4_-_110736505 0.18 ENST00000609440.1
RP11-602N24.3
chr10_-_120840309 0.18 ENST00000369144.3
eukaryotic translation initiation factor 3, subunit A
chr1_-_154531095 0.17 ENST00000292211.4
ubiquitin-conjugating enzyme E2Q family member 1
chr17_-_18218237 0.17 ENST00000542570.1
topoisomerase (DNA) III alpha
chr1_+_11866207 0.17 ENST00000312413.6
ENST00000346436.6
chloride channel, voltage-sensitive 6
chr5_+_34656450 0.17 ENST00000514527.1
retinoic acid induced 14
chr15_-_72668185 0.17 ENST00000457859.2
ENST00000566304.1
ENST00000567159.1
ENST00000429918.2
hexosaminidase A (alpha polypeptide)
chrX_+_129040094 0.17 ENST00000425117.2
UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
chr17_+_42422629 0.17 ENST00000589536.1
ENST00000587109.1
ENST00000587518.1
granulin
chr9_-_37576226 0.17 ENST00000432825.2
F-box protein 10
chr8_-_107782463 0.17 ENST00000311955.3
actin-binding Rho activating protein

Network of associatons between targets according to the STRING database.

First level regulatory network of TFEC_MITF_ARNTL_BHLHE41

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.4 3.3 GO:1904637 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.3 1.3 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.3 1.3 GO:0043323 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.2 0.7 GO:0002352 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597) positive regulation of apoptotic DNA fragmentation(GO:1902512)
0.2 0.9 GO:1901805 beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.2 0.5 GO:0051037 regulation of transcription involved in meiotic cell cycle(GO:0051037)
0.2 2.6 GO:0060155 platelet dense granule organization(GO:0060155)
0.1 0.4 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
0.1 0.6 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.1 0.4 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.1 0.8 GO:0016139 glycoside catabolic process(GO:0016139)
0.1 0.3 GO:0002276 basophil activation involved in immune response(GO:0002276) basophil activation(GO:0045575)
0.1 0.2 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 0.2 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 0.2 GO:1902568 regulation of eosinophil degranulation(GO:0043309) positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.1 0.4 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1 0.4 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1 0.3 GO:0042823 pyridoxal phosphate biosynthetic process(GO:0042823)
0.1 0.9 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1 0.6 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.1 0.2 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.1 0.2 GO:0090301 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.1 0.2 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.1 0.2 GO:0002188 translation reinitiation(GO:0002188)
0.1 0.2 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.1 0.2 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.1 0.2 GO:1902559 3'-phosphoadenosine 5'-phosphosulfate transport(GO:0046963) 3'-phospho-5'-adenylyl sulfate transmembrane transport(GO:1902559)
0.1 0.2 GO:0060168 positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.1 0.3 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.1 0.2 GO:0043181 vacuolar sequestering(GO:0043181)
0.1 0.8 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.2 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.0 0.2 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.5 GO:0015808 L-alanine transport(GO:0015808)
0.0 1.0 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.4 GO:1990034 cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034)
0.0 0.2 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.5 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:0046901 tetrahydrofolylpolyglutamate biosynthetic process(GO:0046901)
0.0 0.1 GO:0006258 UDP-glucose catabolic process(GO:0006258)
0.0 0.1 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.0 0.1 GO:0043474 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0 0.6 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.1 GO:0021882 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) regulation of amacrine cell differentiation(GO:1902869) positive regulation of amacrine cell differentiation(GO:1902871)
0.0 0.2 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 0.0 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.3 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.0 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.0 0.1 GO:1901207 regulation of heart looping(GO:1901207)
0.0 0.1 GO:0009786 regulation of asymmetric cell division(GO:0009786) mesonephric duct morphogenesis(GO:0072180)
0.0 0.4 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.4 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0 0.2 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.0 0.1 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.0 0.4 GO:0071907 determination of digestive tract left/right asymmetry(GO:0071907)
0.0 0.2 GO:0006489 dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
0.0 0.5 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.1 GO:0006059 hexitol metabolic process(GO:0006059)
0.0 0.0 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.0 0.1 GO:0061433 cellular response to caloric restriction(GO:0061433) negative regulation of oligodendrocyte progenitor proliferation(GO:0070446)
0.0 0.2 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.2 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.2 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
0.0 0.4 GO:0060613 fat pad development(GO:0060613)
0.0 0.1 GO:0070495 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495) negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0 0.2 GO:0045445 myoblast differentiation(GO:0045445)
0.0 0.1 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.1 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.1 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.0 0.1 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.0 0.7 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.0 0.5 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.5 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.5 GO:0015886 heme transport(GO:0015886)
0.0 0.1 GO:0006043 glucosamine catabolic process(GO:0006043)
0.0 0.3 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.1 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.1 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.0 0.0 GO:0048565 digestive tract development(GO:0048565)
0.0 0.3 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.4 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.1 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.0 0.1 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.0 0.3 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.0 0.2 GO:0032490 detection of molecule of bacterial origin(GO:0032490)
0.0 0.2 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.1 GO:0006147 guanine catabolic process(GO:0006147)
0.0 0.1 GO:0046709 IDP metabolic process(GO:0046707) IDP catabolic process(GO:0046709)
0.0 0.1 GO:0032900 viral protein processing(GO:0019082) negative regulation of neurotrophin production(GO:0032900) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.0 0.1 GO:0070309 positive regulation by virus of viral protein levels in host cell(GO:0046726) lens fiber cell morphogenesis(GO:0070309)
0.0 0.2 GO:1990834 response to odorant(GO:1990834)
0.0 0.1 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.1 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.0 0.1 GO:2000775 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775)
0.0 0.1 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.1 GO:0034059 response to anoxia(GO:0034059)
0.0 0.8 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.0 0.1 GO:2000657 regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657)
0.0 0.3 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0 0.1 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.2 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.0 0.1 GO:2000538 regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.0 0.2 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.0 0.1 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.1 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
0.0 0.2 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.1 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.9 GO:0034724 DNA replication-independent nucleosome organization(GO:0034724)
0.0 0.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.1 GO:0060620 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0 0.8 GO:0033572 transferrin transport(GO:0033572)
0.0 0.2 GO:0070459 prolactin secretion(GO:0070459)
0.0 0.1 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.1 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.0 0.1 GO:1902683 positive regulation of long-term neuronal synaptic plasticity(GO:0048170) regulation of receptor localization to synapse(GO:1902683)
0.0 0.3 GO:0035878 nail development(GO:0035878)
0.0 0.1 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.3 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.1 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.1 GO:0006788 heme oxidation(GO:0006788) negative regulation of mast cell cytokine production(GO:0032764) regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.0 0.1 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.0 0.1 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
0.0 0.0 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:2000506 negative regulation of energy homeostasis(GO:2000506)
0.0 0.4 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.3 GO:0006265 DNA topological change(GO:0006265)
0.0 0.1 GO:0032053 ciliary basal body organization(GO:0032053) positive regulation of protein localization to cilium(GO:1903566)
0.0 0.2 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.0 0.1 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.0 0.0 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.1 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.3 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.0 0.1 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.2 GO:2000615 regulation of histone H3-K9 acetylation(GO:2000615)
0.0 0.2 GO:0046321 positive regulation of fatty acid oxidation(GO:0046321)
0.0 0.1 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.1 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.2 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.0 GO:0002840 T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840)
0.0 0.0 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.0 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.0 0.1 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:1902904 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.0 0.1 GO:0045900 negative regulation of translational elongation(GO:0045900)
0.0 0.1 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501)
0.0 0.2 GO:0030575 nuclear body organization(GO:0030575)
0.0 0.3 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.1 GO:0036506 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.0 0.1 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.0 GO:0044209 AMP salvage(GO:0044209)
0.0 0.1 GO:1900368 regulation of RNA interference(GO:1900368)
0.0 0.2 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.0 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.0 0.0 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.0 GO:0019516 lactate oxidation(GO:0019516)
0.0 0.0 GO:1902903 regulation of fibril organization(GO:1902903)
0.0 0.0 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.0 0.2 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.2 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.1 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.2 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 1.3 GO:0044194 cytolytic granule(GO:0044194)
0.1 0.5 GO:0033186 CAF-1 complex(GO:0033186)
0.1 0.3 GO:0043614 multi-eIF complex(GO:0043614)
0.1 0.3 GO:0044279 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.1 0.6 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.1 0.3 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 2.5 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 0.4 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.1 0.6 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 0.3 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.1 0.7 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.3 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.3 GO:0071817 MMXD complex(GO:0071817)
0.0 0.1 GO:0001534 radial spoke(GO:0001534)
0.0 0.5 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.8 GO:0030897 HOPS complex(GO:0030897)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.5 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.3 GO:0097452 GAIT complex(GO:0097452)
0.0 0.9 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.3 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.0 GO:0035101 FACT complex(GO:0035101)
0.0 0.5 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.1 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.4 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.3 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.1 GO:0035838 growing cell tip(GO:0035838)
0.0 0.4 GO:0043219 lateral loop(GO:0043219)
0.0 0.2 GO:0001740 Barr body(GO:0001740)
0.0 0.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.2 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.2 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.5 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 1.6 GO:0016235 aggresome(GO:0016235)
0.0 0.2 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.3 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.2 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.0 GO:0019034 viral replication complex(GO:0019034)
0.0 0.3 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 0.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.1 GO:0033176 proton-transporting V-type ATPase complex(GO:0033176)
0.0 0.3 GO:0042555 MCM complex(GO:0042555)
0.0 0.1 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 0.0 GO:0005595 collagen type XII trimer(GO:0005595)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.1 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.9 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.1 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.0 0.0 GO:0008043 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0 0.4 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 0.2 GO:0000782 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 0.2 GO:0030914 STAGA complex(GO:0030914)
0.0 1.5 GO:0005901 caveola(GO:0005901)
0.0 0.1 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 0.3 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.1 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.2 0.9 GO:0004348 glucosylceramidase activity(GO:0004348)
0.2 0.5 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.1 0.4 GO:0070361 mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.1 0.9 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.1 0.6 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1 0.4 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.1 0.3 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.1 0.8 GO:0016936 galactoside binding(GO:0016936)
0.1 1.0 GO:0019826 oxygen sensor activity(GO:0019826)
0.1 0.3 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.1 0.4 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 0.4 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 0.2 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 0.3 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 2.9 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 0.3 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.1 0.2 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.1 0.7 GO:0051434 BH3 domain binding(GO:0051434)
0.1 0.2 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1 0.2 GO:0030984 kininogen binding(GO:0030984)
0.1 0.6 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.1 0.2 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1 0.3 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.3 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1 0.3 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1 0.2 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.1 0.3 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.4 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.5 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0 0.2 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.1 GO:0008841 tetrahydrofolylpolyglutamate synthase activity(GO:0004326) dihydrofolate synthase activity(GO:0008841)
0.0 1.0 GO:0015929 hexosaminidase activity(GO:0015929)
0.0 0.2 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.2 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.0 0.2 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 1.7 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.8 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.2 GO:0019770 IgG receptor activity(GO:0019770)
0.0 0.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.1 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.0 0.1 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 0.1 GO:0035240 dopamine binding(GO:0035240)
0.0 0.3 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.1 GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0 0.1 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.0 0.1 GO:0015633 zinc transporting ATPase activity(GO:0015633)
0.0 0.0 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 1.0 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.2 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.2 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.2 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.3 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.1 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.0 0.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.2 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.1 GO:0015207 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.0 0.3 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.1 GO:0008892 guanine deaminase activity(GO:0008892)
0.0 0.7 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.2 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.2 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 0.0 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.0 0.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.1 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0 0.1 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.2 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.2 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.1 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.1 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) aspartic-type endopeptidase inhibitor activity(GO:0019828) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.1 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.1 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.1 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.0 0.1 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.1 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.0 GO:0008047 enzyme activator activity(GO:0008047)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.6 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.1 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.1 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.1 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.2 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.1 GO:0004306 ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.0 0.1 GO:0019144 ADP-sugar diphosphatase activity(GO:0019144) adenosine-diphosphatase activity(GO:0043262)
0.0 0.3 GO:0010181 FMN binding(GO:0010181)
0.0 0.9 GO:0050699 WW domain binding(GO:0050699)
0.0 1.5 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.3 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.1 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.3 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.1 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.3 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.0 GO:0016898 D-lactate dehydrogenase (cytochrome) activity(GO:0004458) oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor(GO:0016898)
0.0 0.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.1 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.1 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.0 GO:0001602 peptide YY receptor activity(GO:0001601) pancreatic polypeptide receptor activity(GO:0001602)
0.0 0.1 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.7 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.7 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.6 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.0 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.1 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 2.2 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 1.4 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 1.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 2.3 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.8 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.8 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.6 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.3 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.5 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.4 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.5 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.4 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.7 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.2 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.9 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.6 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 1.2 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.3 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.3 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation