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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for TFAP4_MSC

Z-value: 0.80

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Transcription factors associated with TFAP4_MSC

Gene Symbol Gene ID Gene Info
TFAP4
ENSG00000090447.7 transcription factor AP-4
MSC
ENSG00000178860.8 musculin

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TFAP4hg19_v2_chr16_-_4323015_4323076-0.871.3e-01Click!
MSChg19_v2_chr8_-_72756667_727567360.742.6e-01Click!

Activity profile of TFAP4_MSC motif

Sorted Z-values of TFAP4_MSC motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_123706338 1.11 ENST00000521608.1
RP11-973F15.1
long intergenic non-protein coding RNA 1151
chr15_-_40401062 0.99 ENST00000354670.4
ENST00000559701.1
ENST00000557870.1
ENST00000558774.1
BMF
Bcl2 modifying factor
chr2_-_42160486 0.95 ENST00000427054.1
AC104654.2
AC104654.2
chr2_+_33701286 0.66 ENST00000403687.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr22_-_21905120 0.60 ENST00000331505.5
RIMBP3C
RIMS binding protein 3C
chr12_-_56753858 0.47 ENST00000314128.4
ENST00000557235.1
ENST00000418572.2
STAT2
signal transducer and activator of transcription 2, 113kDa
chr17_+_36508111 0.46 ENST00000331159.5
ENST00000577233.1
SOCS7
suppressor of cytokine signaling 7
chr2_-_158295915 0.45 ENST00000418920.1
CYTIP
cytohesin 1 interacting protein
chr8_-_144512576 0.45 ENST00000333480.2
MAFA
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A
chr10_+_91087651 0.42 ENST00000371818.4
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr17_+_58018269 0.42 ENST00000591035.1
RP11-178C3.1
Uncharacterized protein
chr6_-_133055896 0.38 ENST00000367927.5
ENST00000425515.2
ENST00000207771.3
ENST00000392393.3
ENST00000450865.2
ENST00000392394.2
VNN3
vanin 3
chr11_+_64059464 0.36 ENST00000394525.2
KCNK4
potassium channel, subfamily K, member 4
chr2_+_231280954 0.35 ENST00000409824.1
ENST00000409341.1
ENST00000409112.1
ENST00000340126.4
ENST00000341950.4
SP100
SP100 nuclear antigen
chr2_-_158345341 0.34 ENST00000435117.1
CYTIP
cytohesin 1 interacting protein
chr13_-_41635512 0.33 ENST00000405737.2
ELF1
E74-like factor 1 (ets domain transcription factor)
chr12_+_104458235 0.33 ENST00000229330.4
HCFC2
host cell factor C2
chr5_-_141257954 0.32 ENST00000456271.1
ENST00000394536.3
ENST00000503492.1
ENST00000287008.3
PCDH1
protocadherin 1
chr2_+_97203082 0.31 ENST00000454558.2
ARID5A
AT rich interactive domain 5A (MRF1-like)
chr6_-_19804877 0.31 ENST00000447250.1
RP4-625H18.2
RP4-625H18.2
chr17_+_48133459 0.31 ENST00000320031.8
ITGA3
integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
chr17_+_7462103 0.31 ENST00000396545.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr2_+_231280908 0.30 ENST00000427101.2
ENST00000432979.1
SP100
SP100 nuclear antigen
chr17_+_7461849 0.30 ENST00000338784.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr7_+_134832808 0.29 ENST00000275767.3
TMEM140
transmembrane protein 140
chr21_+_30673091 0.29 ENST00000447177.1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chrX_-_108868390 0.28 ENST00000372101.2
KCNE1L
KCNE1-like
chr5_+_102201430 0.27 ENST00000438793.3
ENST00000346918.2
PAM
peptidylglycine alpha-amidating monooxygenase
chrX_+_135279179 0.27 ENST00000370676.3
FHL1
four and a half LIM domains 1
chr17_+_7482785 0.27 ENST00000250092.6
ENST00000380498.6
ENST00000584502.1
CD68
CD68 molecule
chr17_-_15469590 0.27 ENST00000312127.2
CDRT1
CMT duplicated region transcript 1; Uncharacterized protein
chr3_+_188817891 0.27 ENST00000412373.1
TPRG1
tumor protein p63 regulated 1
chr17_+_48133330 0.27 ENST00000544892.1
ITGA3
integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
chr11_+_66742742 0.26 ENST00000308963.4
C11orf86
chromosome 11 open reading frame 86
chr9_+_6757634 0.26 ENST00000543771.1
ENST00000401787.3
ENST00000381306.3
ENST00000381309.3
KDM4C
lysine (K)-specific demethylase 4C
chr5_-_172755056 0.26 ENST00000520648.1
STC2
stanniocalcin 2
chr2_-_158345462 0.26 ENST00000439355.1
ENST00000540637.1
CYTIP
cytohesin 1 interacting protein
chr19_+_35521572 0.26 ENST00000262631.5
SCN1B
sodium channel, voltage-gated, type I, beta subunit
chr14_+_24584508 0.26 ENST00000559354.1
ENST00000560459.1
ENST00000559593.1
ENST00000396941.4
ENST00000396936.1
DCAF11
DDB1 and CUL4 associated factor 11
chr7_+_48128854 0.26 ENST00000436673.1
ENST00000429491.2
UPP1
uridine phosphorylase 1
chr1_-_153585539 0.25 ENST00000368706.4
S100A16
S100 calcium binding protein A16
chr2_-_225811747 0.25 ENST00000409592.3
DOCK10
dedicator of cytokinesis 10
chr19_+_35521699 0.25 ENST00000415950.3
SCN1B
sodium channel, voltage-gated, type I, beta subunit
chr16_-_31105870 0.24 ENST00000394971.3
VKORC1
vitamin K epoxide reductase complex, subunit 1
chr8_-_49833978 0.24 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr11_+_18417948 0.24 ENST00000542179.1
LDHA
lactate dehydrogenase A
chr11_-_1507965 0.24 ENST00000329957.6
MOB2
MOB kinase activator 2
chr15_+_74287035 0.24 ENST00000395132.2
ENST00000268059.6
ENST00000354026.6
ENST00000268058.3
ENST00000565898.1
ENST00000569477.1
ENST00000569965.1
ENST00000567543.1
ENST00000436891.3
ENST00000435786.2
ENST00000564428.1
ENST00000359928.4
PML
promyelocytic leukemia
chr7_+_48128816 0.24 ENST00000395564.4
UPP1
uridine phosphorylase 1
chr5_+_102201722 0.24 ENST00000274392.9
ENST00000455264.2
PAM
peptidylglycine alpha-amidating monooxygenase
chr10_+_82219058 0.24 ENST00000372156.1
TSPAN14
tetraspanin 14
chr19_-_8642289 0.23 ENST00000596675.1
ENST00000338257.8
MYO1F
myosin IF
chr14_-_91282726 0.23 ENST00000328459.6
ENST00000357056.2
TTC7B
tetratricopeptide repeat domain 7B
chr6_-_133055815 0.23 ENST00000509351.1
ENST00000417437.2
ENST00000414302.2
ENST00000423615.2
ENST00000427187.2
ENST00000275223.3
ENST00000519686.2
VNN3
vanin 3
chr22_+_38071615 0.23 ENST00000215909.5
LGALS1
lectin, galactoside-binding, soluble, 1
chr17_+_65027509 0.23 ENST00000375684.1
AC005544.1
Uncharacterized protein
chr22_-_39640756 0.23 ENST00000331163.6
PDGFB
platelet-derived growth factor beta polypeptide
chrX_+_70521584 0.22 ENST00000373829.3
ENST00000538820.1
ITGB1BP2
integrin beta 1 binding protein (melusin) 2
chr3_-_65583561 0.22 ENST00000460329.2
MAGI1
membrane associated guanylate kinase, WW and PDZ domain containing 1
chr7_+_48128194 0.22 ENST00000416681.1
ENST00000331803.4
ENST00000432131.1
UPP1
uridine phosphorylase 1
chr16_-_31106211 0.21 ENST00000532364.1
ENST00000529564.1
ENST00000319788.7
ENST00000354895.4
ENST00000394975.2
RP11-196G11.1
VKORC1
Uncharacterized protein
vitamin K epoxide reductase complex, subunit 1
chr10_-_75676400 0.21 ENST00000412307.2
C10orf55
chromosome 10 open reading frame 55
chr8_+_81397846 0.21 ENST00000379091.4
ZBTB10
zinc finger and BTB domain containing 10
chr16_-_103572 0.21 ENST00000293860.5
POLR3K
polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa
chr7_-_127671674 0.21 ENST00000478726.1
LRRC4
leucine rich repeat containing 4
chr6_+_17281573 0.21 ENST00000379052.5
RBM24
RNA binding motif protein 24
chr7_+_48128316 0.21 ENST00000341253.4
UPP1
uridine phosphorylase 1
chr5_+_135364584 0.21 ENST00000442011.2
ENST00000305126.8
TGFBI
transforming growth factor, beta-induced, 68kDa
chr16_-_31106048 0.21 ENST00000300851.6
VKORC1
vitamin K epoxide reductase complex, subunit 1
chr19_-_39735646 0.20 ENST00000413851.2
IFNL3
interferon, lambda 3
chr2_+_97202480 0.20 ENST00000357485.3
ARID5A
AT rich interactive domain 5A (MRF1-like)
chr12_-_118628315 0.20 ENST00000540561.1
TAOK3
TAO kinase 3
chr5_+_102201687 0.20 ENST00000304400.7
PAM
peptidylglycine alpha-amidating monooxygenase
chr17_-_61778528 0.20 ENST00000584645.1
LIMD2
LIM domain containing 2
chr1_+_155051305 0.20 ENST00000368408.3
EFNA3
ephrin-A3
chr2_-_154335300 0.20 ENST00000325926.3
RPRM
reprimo, TP53 dependent G2 arrest mediator candidate
chr2_+_27505260 0.20 ENST00000380075.2
ENST00000296098.4
TRIM54
tripartite motif containing 54
chr19_+_18699599 0.20 ENST00000450195.2
C19orf60
chromosome 19 open reading frame 60
chr17_-_41132010 0.20 ENST00000409103.1
ENST00000360221.4
PTGES3L-AARSD1
PTGES3L-AARSD1 readthrough
chr8_+_98788057 0.20 ENST00000517924.1
LAPTM4B
lysosomal protein transmembrane 4 beta
chr2_-_231860596 0.20 ENST00000441063.1
ENST00000434094.1
ENST00000418330.1
ENST00000457803.1
ENST00000414876.1
ENST00000446741.1
ENST00000426904.1
AC105344.2
SPATA3 antisense RNA 1 (head to head)
chr19_-_48018203 0.20 ENST00000595227.1
ENST00000593761.1
ENST00000263354.3
NAPA
N-ethylmaleimide-sensitive factor attachment protein, alpha
chr1_-_204135450 0.19 ENST00000272190.8
ENST00000367195.2
REN
renin
chr3_+_193809263 0.19 ENST00000457815.1
RP11-135A1.3
RP11-135A1.3
chr11_-_62323702 0.19 ENST00000530285.1
AHNAK
AHNAK nucleoprotein
chr3_+_32433363 0.19 ENST00000465248.1
CMTM7
CKLF-like MARVEL transmembrane domain containing 7
chr15_+_74287118 0.18 ENST00000563500.1
PML
promyelocytic leukemia
chr19_+_1041187 0.18 ENST00000531467.1
ABCA7
ATP-binding cassette, sub-family A (ABC1), member 7
chr1_+_180165672 0.18 ENST00000443059.1
QSOX1
quiescin Q6 sulfhydryl oxidase 1
chr5_-_139930713 0.18 ENST00000602657.1
SRA1
steroid receptor RNA activator 1
chr11_-_85430356 0.17 ENST00000526999.1
SYTL2
synaptotagmin-like 2
chr8_-_135522425 0.17 ENST00000521673.1
ZFAT
zinc finger and AT hook domain containing
chr9_+_6758024 0.17 ENST00000442236.2
KDM4C
lysine (K)-specific demethylase 4C
chr7_+_55086794 0.17 ENST00000275493.2
ENST00000442591.1
EGFR
epidermal growth factor receptor
chr6_+_30749649 0.17 ENST00000422944.1
HCG20
HLA complex group 20 (non-protein coding)
chr14_-_77495007 0.17 ENST00000238647.3
IRF2BPL
interferon regulatory factor 2 binding protein-like
chr16_+_55522536 0.17 ENST00000570283.1
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr8_-_49834299 0.17 ENST00000396822.1
SNAI2
snail family zinc finger 2
chr19_+_35521616 0.17 ENST00000595652.1
SCN1B
sodium channel, voltage-gated, type I, beta subunit
chr1_+_153600869 0.17 ENST00000292169.1
ENST00000368696.3
ENST00000436839.1
S100A1
S100 calcium binding protein A1
chr7_+_35756186 0.17 ENST00000430518.1
AC018647.3
AC018647.3
chr17_-_54893250 0.17 ENST00000397862.2
C17orf67
chromosome 17 open reading frame 67
chr6_-_117747015 0.17 ENST00000368508.3
ENST00000368507.3
ROS1
c-ros oncogene 1 , receptor tyrosine kinase
chr5_+_102201509 0.16 ENST00000348126.2
ENST00000379787.4
PAM
peptidylglycine alpha-amidating monooxygenase
chr2_+_101437487 0.16 ENST00000427413.1
ENST00000542504.1
NPAS2
neuronal PAS domain protein 2
chr22_+_30792980 0.16 ENST00000403484.1
ENST00000405717.3
ENST00000402592.3
SEC14L2
SEC14-like 2 (S. cerevisiae)
chr7_+_99699280 0.16 ENST00000421755.1
AP4M1
adaptor-related protein complex 4, mu 1 subunit
chr6_-_110736742 0.16 ENST00000368924.3
ENST00000368923.3
DDO
D-aspartate oxidase
chrX_+_135278908 0.16 ENST00000539015.1
ENST00000370683.1
FHL1
four and a half LIM domains 1
chr12_+_104850740 0.16 ENST00000547956.1
ENST00000549260.1
ENST00000303694.5
CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
chr22_+_35695793 0.16 ENST00000456128.1
ENST00000449058.2
ENST00000411850.1
ENST00000425375.1
ENST00000436462.2
ENST00000382034.5
TOM1
target of myb1 (chicken)
chr19_+_18699535 0.16 ENST00000358607.6
C19orf60
chromosome 19 open reading frame 60
chr10_-_69991865 0.16 ENST00000373673.3
ATOH7
atonal homolog 7 (Drosophila)
chr22_+_30792846 0.16 ENST00000312932.9
ENST00000428195.1
SEC14L2
SEC14-like 2 (S. cerevisiae)
chr6_+_46761118 0.15 ENST00000230588.4
MEP1A
meprin A, alpha (PABA peptide hydrolase)
chr10_-_73848531 0.15 ENST00000373109.2
SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr21_+_30672433 0.15 ENST00000451655.1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr9_+_6758109 0.15 ENST00000536108.1
KDM4C
lysine (K)-specific demethylase 4C
chr10_+_81272287 0.15 ENST00000520547.2
EIF5AL1
eukaryotic translation initiation factor 5A-like 1
chr2_+_95537170 0.15 ENST00000295201.4
TEKT4
tektin 4
chr4_-_74864386 0.15 ENST00000296027.4
CXCL5
chemokine (C-X-C motif) ligand 5
chr3_+_13521833 0.15 ENST00000458642.1
ENST00000405478.1
ENST00000405025.1
ENST00000522202.1
ENST00000418189.1
HDAC11
histone deacetylase 11
chr6_-_72129806 0.15 ENST00000413945.1
ENST00000602878.1
ENST00000436803.1
ENST00000421704.1
ENST00000441570.1
LINC00472
long intergenic non-protein coding RNA 472
chr12_+_122150646 0.15 ENST00000449592.2
TMEM120B
transmembrane protein 120B
chr9_+_21440440 0.14 ENST00000276927.1
IFNA1
interferon, alpha 1
chr15_+_65337708 0.14 ENST00000334287.2
SLC51B
solute carrier family 51, beta subunit
chr12_-_54121212 0.14 ENST00000548263.1
ENST00000430117.2
ENST00000550804.1
ENST00000549173.1
ENST00000551900.1
ENST00000546619.1
ENST00000548177.1
ENST00000549349.1
CALCOCO1
calcium binding and coiled-coil domain 1
chr3_+_49058444 0.14 ENST00000326925.6
ENST00000395458.2
NDUFAF3
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr1_-_201346761 0.14 ENST00000455702.1
ENST00000422165.1
ENST00000367318.5
ENST00000367320.2
ENST00000438742.1
ENST00000412633.1
ENST00000458432.2
ENST00000421663.2
ENST00000367322.1
ENST00000509001.1
TNNT2
troponin T type 2 (cardiac)
chr17_+_73028676 0.14 ENST00000581589.1
KCTD2
potassium channel tetramerization domain containing 2
chr3_+_32433154 0.14 ENST00000334983.5
ENST00000349718.4
CMTM7
CKLF-like MARVEL transmembrane domain containing 7
chr5_-_58571935 0.14 ENST00000503258.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr17_-_47755338 0.14 ENST00000508805.1
ENST00000515508.2
ENST00000451526.2
ENST00000507970.1
SPOP
speckle-type POZ protein
chr3_+_3841108 0.14 ENST00000319331.3
LRRN1
leucine rich repeat neuronal 1
chr1_-_209792111 0.14 ENST00000455193.1
LAMB3
laminin, beta 3
chr7_+_99699179 0.14 ENST00000438383.1
ENST00000429084.1
ENST00000359593.4
ENST00000439416.1
AP4M1
adaptor-related protein complex 4, mu 1 subunit
chr11_+_73675873 0.14 ENST00000537753.1
ENST00000542350.1
DNAJB13
DnaJ (Hsp40) homolog, subfamily B, member 13
chr11_-_70507901 0.14 ENST00000449833.2
ENST00000357171.3
ENST00000449116.2
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr9_+_20927764 0.14 ENST00000603044.1
ENST00000604254.1
FOCAD
focadhesin
chr1_+_19967014 0.14 ENST00000428975.1
NBL1
neuroblastoma 1, DAN family BMP antagonist
chr7_-_74867509 0.14 ENST00000426327.3
GATSL2
GATS protein-like 2
chr3_+_49057876 0.14 ENST00000326912.4
NDUFAF3
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr7_-_41742697 0.14 ENST00000242208.4
INHBA
inhibin, beta A
chr6_-_26250835 0.14 ENST00000446824.2
HIST1H3F
histone cluster 1, H3f
chr15_+_63354769 0.14 ENST00000558910.1
TPM1
tropomyosin 1 (alpha)
chr1_+_144989309 0.14 ENST00000596396.1
AL590452.1
Uncharacterized protein
chr20_-_48770244 0.13 ENST00000371650.5
ENST00000371652.4
ENST00000557021.1
TMEM189
transmembrane protein 189
chr19_+_7587555 0.13 ENST00000601003.1
MCOLN1
mucolipin 1
chr10_+_47746929 0.13 ENST00000340243.6
ENST00000374277.5
ENST00000449464.2
ENST00000538825.1
ENST00000335083.5
ANXA8L2
AL603965.1
annexin A8-like 2
Protein LOC100996760
chr19_+_1041212 0.13 ENST00000433129.1
ABCA7
ATP-binding cassette, sub-family A (ABC1), member 7
chr9_-_16705069 0.13 ENST00000471301.2
BNC2
basonuclin 2
chr10_-_73611046 0.13 ENST00000394934.1
ENST00000394936.3
PSAP
prosaposin
chr14_-_38028689 0.13 ENST00000553425.1
RP11-356O9.2
RP11-356O9.2
chr4_-_80994210 0.13 ENST00000403729.2
ANTXR2
anthrax toxin receptor 2
chr10_-_73533255 0.13 ENST00000394957.3
C10orf54
chromosome 10 open reading frame 54
chr10_+_1102303 0.13 ENST00000381329.1
WDR37
WD repeat domain 37
chr6_-_132834184 0.13 ENST00000367941.2
ENST00000367937.4
STX7
syntaxin 7
chr6_-_19804973 0.13 ENST00000457670.1
ENST00000607810.1
ENST00000606628.1
RP4-625H18.2
RP4-625H18.2
chr1_-_154842741 0.13 ENST00000271915.4
KCNN3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr2_-_230786619 0.13 ENST00000389045.3
ENST00000409677.1
TRIP12
thyroid hormone receptor interactor 12
chr16_+_4606347 0.13 ENST00000444310.4
C16orf96
chromosome 16 open reading frame 96
chr15_-_67546963 0.13 ENST00000561452.1
ENST00000261880.5
AAGAB
alpha- and gamma-adaptin binding protein
chr2_+_54198210 0.13 ENST00000607452.1
ENST00000422521.2
ACYP2
acylphosphatase 2, muscle type
chr3_+_107318157 0.13 ENST00000406780.1
BBX
bobby sox homolog (Drosophila)
chr7_-_99698338 0.12 ENST00000354230.3
ENST00000425308.1
MCM7
minichromosome maintenance complex component 7
chr17_-_41174424 0.12 ENST00000355653.3
VAT1
vesicle amine transport 1
chr17_-_73851285 0.12 ENST00000589642.1
ENST00000593002.1
ENST00000590221.1
ENST00000344296.4
ENST00000587374.1
ENST00000585462.1
ENST00000433525.2
ENST00000254806.3
WBP2
WW domain binding protein 2
chr5_+_150040403 0.12 ENST00000517768.1
ENST00000297130.4
MYOZ3
myozenin 3
chr19_-_19051103 0.12 ENST00000542541.2
ENST00000433218.2
HOMER3
homer homolog 3 (Drosophila)
chr15_-_55562479 0.12 ENST00000564609.1
RAB27A
RAB27A, member RAS oncogene family
chr4_-_46391367 0.12 ENST00000503806.1
ENST00000356504.1
ENST00000514090.1
ENST00000506961.1
GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr17_+_7462031 0.12 ENST00000380535.4
TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr15_-_90039805 0.12 ENST00000544600.1
ENST00000268122.4
RHCG
Rh family, C glycoprotein
chr5_+_66124590 0.12 ENST00000490016.2
ENST00000403666.1
ENST00000450827.1
MAST4
microtubule associated serine/threonine kinase family member 4
chr10_-_111683308 0.12 ENST00000502935.1
ENST00000322238.8
ENST00000369680.4
XPNPEP1
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
chr3_+_32148106 0.12 ENST00000425459.1
ENST00000431009.1
GPD1L
glycerol-3-phosphate dehydrogenase 1-like
chr12_-_54121261 0.12 ENST00000549784.1
ENST00000262059.4
CALCOCO1
calcium binding and coiled-coil domain 1
chr6_-_2751146 0.12 ENST00000268446.5
ENST00000274643.7
MYLK4
myosin light chain kinase family, member 4
chr5_-_80689945 0.12 ENST00000307624.3
ACOT12
acyl-CoA thioesterase 12
chr22_+_31090793 0.11 ENST00000332585.6
ENST00000382310.3
ENST00000446658.2
OSBP2
oxysterol binding protein 2
chr2_+_85822857 0.11 ENST00000306368.4
ENST00000414390.1
ENST00000456023.1
RNF181
ring finger protein 181
chr10_+_75545391 0.11 ENST00000604524.1
ENST00000605216.1
ENST00000398706.2
ZSWIM8
zinc finger, SWIM-type containing 8
chr7_-_27187393 0.11 ENST00000222728.3
HOXA6
homeobox A6
chr17_+_9728828 0.11 ENST00000262441.5
GLP2R
glucagon-like peptide 2 receptor
chr1_+_12042015 0.11 ENST00000412236.1
MFN2
mitofusin 2
chr17_+_1959369 0.11 ENST00000576444.1
ENST00000322941.3
HIC1
hypermethylated in cancer 1
chr12_-_118628350 0.11 ENST00000537952.1
ENST00000537822.1
TAOK3
TAO kinase 3
chr22_-_21580582 0.11 ENST00000424627.1
GGT2
gamma-glutamyltransferase 2
chr14_+_53019822 0.11 ENST00000321662.6
GPR137C
G protein-coupled receptor 137C
chr19_-_59070239 0.11 ENST00000595957.1
ENST00000253023.3
UBE2M
ubiquitin-conjugating enzyme E2M
chr8_-_128231299 0.11 ENST00000500112.1
CCAT1
colon cancer associated transcript 1 (non-protein coding)
chr16_-_79634595 0.11 ENST00000326043.4
ENST00000393350.1
MAF
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
chr12_-_53228079 0.11 ENST00000330553.5
KRT79
keratin 79
chr17_+_26989109 0.11 ENST00000314616.6
ENST00000347486.4
SUPT6H
suppressor of Ty 6 homolog (S. cerevisiae)
chr1_-_153931052 0.11 ENST00000368630.3
ENST00000368633.1
CRTC2
CREB regulated transcription coactivator 2
chr22_+_19705928 0.11 ENST00000383045.3
ENST00000438754.2
SEPT5
septin 5
chr1_+_78354330 0.11 ENST00000440324.1
NEXN
nexilin (F actin binding protein)
chr1_-_24741525 0.10 ENST00000374409.1
STPG1
sperm-tail PG-rich repeat containing 1
chr8_+_98788003 0.10 ENST00000521545.2
LAPTM4B
lysosomal protein transmembrane 4 beta
chr17_-_39183452 0.10 ENST00000361883.5
KRTAP1-5
keratin associated protein 1-5

Network of associatons between targets according to the STRING database.

First level regulatory network of TFAP4_MSC

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0006218 uridine catabolic process(GO:0006218)
0.2 0.7 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.1 0.9 GO:0018032 protein amidation(GO:0018032)
0.1 0.4 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.1 0.3 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.1 0.3 GO:1901076 positive regulation of engulfment of apoptotic cell(GO:1901076)
0.1 0.4 GO:0071469 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976) cellular response to alkaline pH(GO:0071469)
0.1 0.6 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.1 0.4 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.1 0.5 GO:0030578 PML body organization(GO:0030578)
0.1 0.2 GO:0033037 polysaccharide localization(GO:0033037)
0.1 0.7 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.1 0.2 GO:1990936 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.1 0.7 GO:0042373 vitamin K metabolic process(GO:0042373)
0.1 0.6 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.1 0.2 GO:1901258 positive regulation of granulocyte colony-stimulating factor production(GO:0071657) positive regulation of macrophage colony-stimulating factor production(GO:1901258)
0.0 0.1 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.0 0.0 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.2 GO:2000273 positive regulation of receptor activity(GO:2000273)
0.0 0.2 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.0 1.0 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.2 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.1 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.0 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.0 0.2 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.0 0.2 GO:0002317 plasma cell differentiation(GO:0002317) response to isolation stress(GO:0035900)
0.0 0.5 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.0 0.6 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.5 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.2 GO:1903438 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.0 0.2 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.0 0.2 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.0 0.1 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.1 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.0 0.1 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.0 0.1 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.1 GO:0006788 heme oxidation(GO:0006788) negative regulation of mast cell cytokine production(GO:0032764) regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.0 0.2 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.1 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.0 0.1 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
0.0 0.1 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.0 0.6 GO:0097205 renal filtration(GO:0097205)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.1 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.1 GO:0090402 senescence-associated heterochromatin focus assembly(GO:0035986) oncogene-induced cell senescence(GO:0090402)
0.0 0.1 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.2 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.0 0.1 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.0 0.1 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.1 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.1 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0 0.1 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.1 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.0 0.2 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.1 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.0 0.2 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.2 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.1 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.0 0.1 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.1 GO:0098704 fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.0 0.0 GO:0035995 detection of muscle stretch(GO:0035995)
0.0 0.1 GO:2000332 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.0 0.2 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.2 GO:1902961 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.0 0.2 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 0.1 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.1 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.0 GO:0070318 myoblast development(GO:0048627) positive regulation of G0 to G1 transition(GO:0070318)
0.0 0.1 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.2 GO:0007320 insemination(GO:0007320)
0.0 0.0 GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
0.0 0.5 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 0.1 GO:0061734 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.0 0.2 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.2 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.0 0.1 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.1 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.0 0.1 GO:2000814 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 0.1 GO:2000845 testosterone secretion(GO:0035936) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845)
0.0 0.1 GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
0.0 0.2 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.0 0.1 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.1 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.0 0.0 GO:1902908 regulation of melanosome transport(GO:1902908)
0.0 0.1 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.0 GO:0060437 lung growth(GO:0060437)
0.0 0.0 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.0 0.1 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.3 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.1 GO:1901314 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.0 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.0 0.1 GO:0070525 tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
0.0 0.3 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.1 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.0 0.1 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.1 0.5 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 0.2 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.1 0.7 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.7 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.2 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.3 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.1 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.0 0.3 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.1 GO:0043614 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993) astrocyte end-foot(GO:0097450)
0.0 0.1 GO:0045160 myosin I complex(GO:0045160)
0.0 0.3 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:1902912 pyruvate kinase complex(GO:1902912)
0.0 0.1 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.3 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.1 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.6 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.1 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.0 0.3 GO:0090543 Flemming body(GO:0090543)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.1 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.0 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.0 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.2 0.7 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.1 0.9 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.1 0.7 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.1 0.4 GO:0098782 mechanically-gated potassium channel activity(GO:0098782)
0.1 0.6 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 0.3 GO:0008431 vitamin E binding(GO:0008431)
0.1 0.3 GO:0090556 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 0.2 GO:0030395 lactose binding(GO:0030395)
0.1 0.7 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.2 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.0 0.2 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.1 GO:0051373 FATZ binding(GO:0051373)
0.0 0.0 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.2 GO:0050659 chondroitin 4-sulfotransferase activity(GO:0047756) N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.0 0.2 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.1 GO:0030172 troponin C binding(GO:0030172)
0.0 0.2 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.5 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.1 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.1 GO:0090541 MIT domain binding(GO:0090541)
0.0 0.5 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.1 GO:0030226 alpha-2 macroglobulin receptor activity(GO:0016964) apolipoprotein receptor activity(GO:0030226)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.1 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.1 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.5 GO:0032183 SUMO binding(GO:0032183)
0.0 0.1 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.1 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.1 GO:0098808 mRNA cap binding(GO:0098808)
0.0 0.1 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.0 0.1 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.4 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.1 GO:0016015 morphogen activity(GO:0016015)
0.0 0.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.0 GO:0031433 telethonin binding(GO:0031433)
0.0 0.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.0 GO:0035240 dopamine binding(GO:0035240)
0.0 0.1 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.9 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.1 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.0 0.4 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.1 GO:0004565 beta-galactosidase activity(GO:0004565)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.6 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.1 PID ATR PATHWAY ATR signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.7 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 1.0 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.4 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.6 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.1 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.4 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection