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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)
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Results for TFAP2B
Z-value: 1.16
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Transcription factors associated with TFAP2B
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr19_-_19739321 Show fit | 0.78 |
ENST00000588461.1
|
lysophosphatidic acid receptor 2 |
|
| chr19_-_39832563 Show fit | 0.64 |
ENST00000599274.1
|
CTC-246B18.10 |
|
| chr17_+_36508826 Show fit | 0.42 |
ENST00000580660.1
|
suppressor of cytokine signaling 7 |
|
| chr17_+_7758374 Show fit | 0.41 |
ENST00000301599.6
ENST00000574668.1 |
transmembrane protein 88 |
|
| chr9_-_34523027 Show fit | 0.40 |
ENST00000399775.2
|
energy homeostasis associated |
|
| chr2_-_55459485 Show fit | 0.40 |
ENST00000451916.1
|
clathrin heavy chain linker domain containing 1 |
|
| chr6_-_35888858 Show fit | 0.34 |
ENST00000507909.1
|
SRSF protein kinase 1 |
|
| chr1_+_221054411 Show fit | 0.34 |
ENST00000427693.1
|
H2.0-like homeobox |
|
| chr1_-_42921915 Show fit | 0.32 |
ENST00000372565.3
ENST00000433602.2 |
zinc finger, MYND-type containing 12 |
|
| chr17_-_42767092 Show fit | 0.32 |
ENST00000588687.1
|
coiled-coil domain containing 43 |
Network of associatons between targets according to the STRING database.
First level regulatory network of TFAP2B
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.8 | GO:0006646 | phosphatidylethanolamine biosynthetic process(GO:0006646) |
| 0.0 | 0.8 | GO:0007202 | activation of phospholipase C activity(GO:0007202) |
| 0.1 | 0.4 | GO:0045747 | positive regulation of Notch signaling pathway(GO:0045747) |
| 0.1 | 0.4 | GO:0006546 | glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464) |
| 0.0 | 0.4 | GO:0021942 | radial glia guided migration of Purkinje cell(GO:0021942) |
| 0.0 | 0.3 | GO:0033277 | abortive mitotic cell cycle(GO:0033277) |
| 0.0 | 0.3 | GO:0061086 | negative regulation of histone H3-K27 methylation(GO:0061086) |
| 0.0 | 0.3 | GO:0045627 | positive regulation of T-helper 1 cell differentiation(GO:0045627) negative regulation of T-helper 2 cell differentiation(GO:0045629) |
| 0.0 | 0.3 | GO:0060754 | positive regulation of mast cell chemotaxis(GO:0060754) |
| 0.0 | 0.3 | GO:0033590 | response to cobalamin(GO:0033590) cellular response to erythropoietin(GO:0036018) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.5 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.1 | 0.3 | GO:0044609 | DBIRD complex(GO:0044609) |
| 0.0 | 0.3 | GO:0043196 | varicosity(GO:0043196) |
| 0.0 | 0.3 | GO:0042105 | alpha-beta T cell receptor complex(GO:0042105) |
| 0.0 | 0.3 | GO:0060091 | kinocilium(GO:0060091) |
| 0.0 | 0.2 | GO:0031084 | BLOC-2 complex(GO:0031084) |
| 0.0 | 0.2 | GO:0044194 | cytolytic granule(GO:0044194) |
| 0.0 | 0.2 | GO:0001739 | sex chromatin(GO:0001739) |
| 0.0 | 0.2 | GO:0061574 | ASAP complex(GO:0061574) |
| 0.0 | 0.2 | GO:0030130 | clathrin coat of trans-Golgi network vesicle(GO:0030130) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 0.8 | GO:0004306 | ethanolamine-phosphate cytidylyltransferase activity(GO:0004306) |
| 0.1 | 0.8 | GO:0070915 | lysophosphatidic acid receptor activity(GO:0070915) |
| 0.1 | 0.4 | GO:0004047 | aminomethyltransferase activity(GO:0004047) |
| 0.1 | 0.3 | GO:0004324 | ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731) |
| 0.1 | 0.3 | GO:0043183 | vascular endothelial growth factor receptor 1 binding(GO:0043183) |
| 0.1 | 0.2 | GO:0031859 | platelet activating factor receptor binding(GO:0031859) |
| 0.1 | 0.2 | GO:0003845 | 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845) |
| 0.0 | 0.2 | GO:0004999 | vasoactive intestinal polypeptide receptor activity(GO:0004999) |
| 0.0 | 0.2 | GO:0004137 | deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797) |
| 0.0 | 0.2 | GO:0004957 | prostaglandin E receptor activity(GO:0004957) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
| 0.0 | 0.1 | PID IL2 PI3K PATHWAY | IL2 signaling events mediated by PI3K |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.8 | REACTOME SYNTHESIS OF PE | Genes involved in Synthesis of PE |
| 0.0 | 0.3 | REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
| 0.0 | 0.3 | REACTOME PECAM1 INTERACTIONS | Genes involved in PECAM1 interactions |
| 0.0 | 0.3 | REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
| 0.0 | 0.3 | REACTOME SPRY REGULATION OF FGF SIGNALING | Genes involved in Spry regulation of FGF signaling |
| 0.0 | 0.3 | REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 0.0 | 0.2 | REACTOME PROSTANOID LIGAND RECEPTORS | Genes involved in Prostanoid ligand receptors |
| 0.0 | 0.2 | REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
| 0.0 | 0.2 | REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR | Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor |
| 0.0 | 0.2 | REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY | Genes involved in Adenylate cyclase activating pathway |